{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T08:28:34Z","timestamp":1790497714504,"version":"4.1.0"},"reference-count":25,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,7,1]],"date-time":"2017-07-01T00:00:00Z","timestamp":1498867200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,2,28]],"date-time":"2017-02-28T00:00:00Z","timestamp":1488240000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemistry and Biophysics Reports"],"published-print":{"date-parts":[[2017,7]]},"DOI":"10.1016\/j.bbrep.2017.02.011","type":"journal-article","created":{"date-parts":[[2017,3,8]],"date-time":"2017-03-08T18:30:18Z","timestamp":1488997818000},"page":"70-75","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["Cyp3a11 is not essential for the formation of murine bile acids"],"prefix":"10.1016","volume":"10","author":[{"given":"Annika","family":"Wahlstr\u00f6m","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samer","family":"Al-Dury","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcus","family":"St\u00e5hlman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fredrik","family":"B\u00e4ckhed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanns-Ulrich","family":"Marschall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrep.2017.02.011_bib1","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1152\/physrev.00010.2008","article-title":"Role of bile acids and bile acid receptors in metabolic regulation","volume":"89","author":"Lefebvre","year":"2009","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.bbrep.2017.02.011_bib2","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/j.bpg.2014.07.004","article-title":"Bile acids, obesity, and the metabolic syndrome","volume":"28","author":"Ma","year":"2014","journal-title":"Best. Pract. Res. Clin. Gastroenterol."},{"key":"10.1016\/j.bbrep.2017.02.011_bib3","doi-asserted-by":"crossref","first-page":"1831","DOI":"10.1021\/jm7015864","article-title":"Novel potent and selective bile acid derivatives as TGR5 agonists: biological screening, structure-activity relationships, and molecular modeling studies","volume":"51","author":"Sato","year":"2008","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bbrep.2017.02.011_bib4","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.cmet.2016.05.005","article-title":"Intestinal crosstalk between bile acids and microbiota and its impact on host metabolism","volume":"24","author":"Wahlstrom","year":"2016","journal-title":"Cell Metab."},{"key":"10.1016\/j.bbrep.2017.02.011_bib5","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1038\/nrendo.2014.60","article-title":"Beyond intestinal soap--bile acids in metabolic control","volume":"10","author":"Kuipers","year":"2014","journal-title":"Nat. Rev. Endocrinol."},{"key":"10.1016\/j.bbrep.2017.02.011_bib6","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.cmet.2013.01.003","article-title":"Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist","volume":"17","author":"Sayin","year":"2013","journal-title":"Cell Metab."},{"key":"10.1016\/j.bbrep.2017.02.011_bib7","doi-asserted-by":"crossref","first-page":"2384","DOI":"10.1038\/ncomms3384","article-title":"Microbiome remodelling leads to inhibition of intestinal farnesoid X receptor signalling and decreased obesity","volume":"4","author":"Li","year":"2013","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bbrep.2017.02.011_bib8","first-page":"667","article-title":"Bile acids. VI. The structure and synthesis of acid II","volume":"226","author":"Hsla","year":"1957","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrep.2017.02.011_bib9","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1016\/S0021-9258(18)64877-X","article-title":"Bile acids. II. metabolism of deoxycholic acid-24-C14 and chenodeoxycholic acid-24-C14 in the rat","volume":"225","author":"Mahowald","year":"1957","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrep.2017.02.011_bib10","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1111\/j.1432-1033.1983.tb07550.x","article-title":"The metabolism of chenodeoxycholic acid to beta-muricholic acid in rat liver","volume":"134","author":"Botham","year":"1983","journal-title":"Eur. J. Biochem."},{"key":"10.1016\/j.bbrep.2017.02.011_bib11","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1194\/jlr.M500427-JLR200","article-title":"Fxr(-\/-) mice adapt to biliary obstruction by enhanced phase I detoxification and renal elimination of bile acids","volume":"47","author":"Marschall","year":"2006","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.bbrep.2017.02.011_bib12","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1194\/jlr.M700034-JLR200","article-title":"Ontogenic development-associated changes in the expression of genes involved in rat bile acid homeostasis","volume":"48","author":"Cuesta","year":"2007","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.bbrep.2017.02.011_bib13","doi-asserted-by":"crossref","first-page":"145","DOI":"10.3109\/03602532.2012.740048","article-title":"Nuclear receptors in bile acid metabolism","volume":"45","author":"Li","year":"2013","journal-title":"Drug Metab. Rev."},{"key":"10.1016\/j.bbrep.2017.02.011_bib14","doi-asserted-by":"crossref","first-page":"e37103","DOI":"10.1371\/journal.pone.0037103","article-title":"PCB 126 and other dioxin-like PCBs specifically suppress hepatic PEPCK expression via the aryl hydrocarbon receptor","volume":"7","author":"Zhang","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.bbrep.2017.02.011_bib15","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.cmet.2015.07.009","article-title":"Roux-en-Y gastric bypass and vertical banded gastroplasty induce long-term changes on the human gut microbiome contributing to fat mass regulation","volume":"22","author":"Tremaroli","year":"2015","journal-title":"Cell Metab."},{"key":"10.1016\/j.bbrep.2017.02.011_bib16","doi-asserted-by":"crossref","first-page":"2461","DOI":"10.1007\/s00018-008-7568-6","article-title":"Bile acids: chemistry, pathochemistry, biology, pathobiology, and therapeutics","volume":"65","author":"Hofmann","year":"2008","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.bbrep.2017.02.011_bib17","doi-asserted-by":"crossref","DOI":"10.1194\/jlr.M071183","article-title":"Cyp2c70 is responsible for the species difference in bile acid metabolism between mice and humans","author":"Takahashi","year":"2016","journal-title":"J. Lipid Res"},{"key":"10.1016\/j.bbrep.2017.02.011_bib18","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1136\/gutjnl-2011-301104","article-title":"Analysis of gut microbial regulation of host gene expression along the length of the gut and regulation of gut microbial ecology through MyD88","volume":"61","author":"Larsson","year":"2012","journal-title":"Gut"},{"key":"10.1016\/j.bbrep.2017.02.011_bib19","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1016\/S0022-2275(20)40663-7","article-title":"Epimerization of the 7-hydroxy group of bile acids by the combination of two kinds of microorganisms with 7 alpha- and 7 beta-hydroxysteroid dehydrogenase activity, respectively","volume":"22","author":"Hirano","year":"1981","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.bbrep.2017.02.011_bib20","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1128\/AEM.44.5.1187-1195.1982","article-title":"Formation of ursodeoxycholic acid from chenodeoxycholic acid by a 7 beta-hydroxysteroid dehydrogenase-elaborating Eubacterium aerofaciens strain cocultured with 7 alpha-hydroxysteroid dehydrogenase-elaborating organisms","volume":"44","author":"MacDonald","year":"1982","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.bbrep.2017.02.011_bib21","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1016\/S0022-2275(20)37929-3","article-title":"Formation of ursodeoxycholic acid from chenodeoxycholic acid in the human colon: studies of the role of 7-ketolithocholic acid as an intermediate","volume":"24","author":"Fromm","year":"1983","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.bbrep.2017.02.011_bib22","first-page":"G161","article-title":"Metabolism in man of 7-ketolithocholic acid: precursor of cheno- and ursodeoxycholic acids","volume":"239","author":"Fromm","year":"1980","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.bbrep.2017.02.011_bib23","first-page":"G67","article-title":"Reduction of 7-ketolithocholic acid by human liver enzyme preparations in vitro","volume":"256","author":"Amuro","year":"1989","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.bbrep.2017.02.011_bib24","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1042\/BJ20110022","article-title":"Hepatic reduction of the secondary bile acid 7-oxolithocholic acid is mediated by 11beta-hydroxysteroid dehydrogenase 1","volume":"436","author":"Odermatt","year":"2011","journal-title":"Biochem. J."},{"key":"10.1016\/j.bbrep.2017.02.011_bib25","doi-asserted-by":"crossref","first-page":"2874","DOI":"10.1194\/jlr.M042499","article-title":"Impaired oxidoreduction by 11beta-hydroxysteroid dehydrogenase 1 results in the accumulation of 7-oxolithocholic acid","volume":"54","author":"Penno","year":"2013","journal-title":"J. Lipid Res."}],"container-title":["Biochemistry and Biophysics Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S240558081730002X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S240558081730002X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,7,25]],"date-time":"2022-07-25T17:44:04Z","timestamp":1658771044000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S240558081730002X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,7]]},"references-count":25,"alternative-id":["S240558081730002X"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrep.2017.02.011","relation":{},"ISSN":["2405-5808"],"issn-type":[{"value":"2405-5808","type":"print"}],"subject":[],"published":{"date-parts":[[2017,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cyp3a11 is not essential for the formation of murine bile acids","name":"articletitle","label":"Article Title"},{"value":"Biochemistry and Biophysics Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbrep.2017.02.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}