{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T18:40:39Z","timestamp":1790793639365,"version":"4.1.0"},"reference-count":47,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,3,1]],"date-time":"2020-03-01T00:00:00Z","timestamp":1583020800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,3,1]],"date-time":"2020-03-01T00:00:00Z","timestamp":1583020800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2019,12,1]],"date-time":"2019-12-01T00:00:00Z","timestamp":1575158400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemistry and Biophysics Reports"],"published-print":{"date-parts":[[2020,3]]},"DOI":"10.1016\/j.bbrep.2019.100715","type":"journal-article","created":{"date-parts":[[2019,12,8]],"date-time":"2019-12-08T23:18:45Z","timestamp":1575847125000},"page":"100715","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"special_numbering":"C","title":["Pharmacological evidence for the use of Cissus assamica as a medicinal plant in the management of pain and pyrexia"],"prefix":"10.1016","volume":"21","author":[{"given":"Trishala","family":"Dutta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arkajyoti","family":"Paul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohuya","family":"Majumder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramiz Ahmed","family":"Sultan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Talha Bin","family":"Emran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrep.2019.100715_bib1","first-page":"123","volume":"vol. 3","author":"Kulkarni","year":"1999"},{"key":"10.1016\/j.bbrep.2019.100715_bib2","first-page":"558","article-title":"Antipyretic activity of Alstonia macrophylla wall ex A. DC: an ethnomedicine of andaman islands","volume":"8","author":"Chattopadhyay","year":"2005","journal-title":"J. Pharm. Pharmaceutical Sci."},{"key":"10.1016\/j.bbrep.2019.100715_bib3","doi-asserted-by":"crossref","first-page":"1880","DOI":"10.1056\/NEJM199406303302609","article-title":"The neurologic basis of fever","volume":"330","author":"Spacer","year":"1994","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.bbrep.2019.100715_bib4","series-title":"Development of Herbal Medicine (A Seminar Lecture)","author":"Said","year":"1995"},{"key":"10.1016\/j.bbrep.2019.100715_bib5","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1016\/S0041-0101(00)00154-9","article-title":"Plants as source of drugs","volume":"39","author":"Rates","year":"2001","journal-title":"Toxicon"},{"key":"10.1016\/j.bbrep.2019.100715_bib6","series-title":"Trade in Medicinal Plants","first-page":"2","author":"FAO","year":"2004"},{"key":"10.1016\/j.bbrep.2019.100715_bib7","series-title":"Medicinal Plants of Bangladesh (Revised and Enlarged)","first-page":"794","author":"Yusuf","year":"2009"},{"issue":"2","key":"10.1016\/j.bbrep.2019.100715_bib8","first-page":"210","article-title":"Studies on the chemical constituents from Cissus assamica","volume":"32","author":"Xie","year":"2009","journal-title":"Zhong Yao Cai"},{"key":"10.1016\/j.bbrep.2019.100715_bib9","volume":"vol. 5","author":"Ghani","year":"2003"},{"issue":"1","key":"10.1016\/j.bbrep.2019.100715_bib10","first-page":"98","article-title":"Phytochemical screening and Extraction: a review","volume":"1","author":"Tiwari","year":"2011","journal-title":"Int. Pharm. Sci."},{"key":"10.1016\/j.bbrep.2019.100715_bib11","first-page":"412","article-title":"Acetic acid for analgesic screening. Fed","volume":"18","author":"Koster","year":"1959","journal-title":"SAVE Proc."},{"key":"10.1016\/j.bbrep.2019.100715_bib12","first-page":"402","volume":"vols. 370\u20131","author":"Vogel","year":"1997"},{"key":"10.1016\/j.bbrep.2019.100715_bib13","doi-asserted-by":"crossref","first-page":"20e24","DOI":"10.4103\/0976-0105.109404","article-title":"Study of pharmacological activities of methanol extract of Jatropha gossypifolia fruits","volume":"4","author":"Apu","year":"2013","journal-title":"J. Basic Clin. Pharm."},{"key":"10.1016\/j.bbrep.2019.100715_bib14","first-page":"502","article-title":"The inhibitory effect of fentanyl and other morphine-like analgesics on the warm water induced tail withdrawal reflex in rats","volume":"13","author":"Janssen","year":"1963","journal-title":"Arzneimittelforschung"},{"key":"10.1016\/j.bbrep.2019.100715_bib15","first-page":"42","article-title":"Analgesic activity of the aqueous root extracts of Lecaniodiscus cupanioides","volume":"19","author":"Adeyemi","year":"2005","journal-title":"West Afr. J. Pharmacol. Drug Res."},{"key":"10.1016\/j.bbrep.2019.100715_bib16","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/S0022-3565(25)09094-9","article-title":"The evaluation of analgesic action pethidine hydrochloride","volume":"80","author":"Woolfe","year":"1994","journal-title":"J. Pharmacol. Exp. Ther."},{"issue":"3","key":"10.1016\/j.bbrep.2019.100715_bib17","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/j.jep.2006.03.015","article-title":"Analgesic activity of some Indian medicinal plants","volume":"106","author":"Malairajan","year":"2006","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.bbrep.2019.100715_bib18","first-page":"1","article-title":"Evaluation of analgesic activity of the methanol extract from the galls of Quercus infectoria (Olivier) in rats.","author":"Fan","year":"2014","journal-title":"Evid Based Complement. Altern. Med."},{"key":"10.1016\/j.bbrep.2019.100715_bib19","first-page":"1103","article-title":"Evaluation of analgesic activity of various extracts of Sida tiagii Bhandari","volume":"69","author":"Kumawat","year":"2012","journal-title":"Acta Pol. Pharm."},{"key":"10.1016\/j.bbrep.2019.100715_bib20","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/S0378-8741(01)00216-1","article-title":"The anti-inflammatory, analgesic and antipyretic activity of Nigella sativa","volume":"76","author":"Al-Ghamdi","year":"2001","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.bbrep.2019.100715_bib21","doi-asserted-by":"crossref","first-page":"138","DOI":"10.3923\/jpt.2009.138.151","article-title":"An evaluation of the anti-inflammatory, antipyretic and antinociceptive effects of Ficus exasperate (Vahl) leaf extract","volume":"4","author":"Woode","year":"2009","journal-title":"J. Pharmacol. Toxicol."},{"key":"10.1016\/j.bbrep.2019.100715_bib22","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1248\/bpb.29.693","article-title":"Immunomodulatory and anti-inflammatory effects of Semecarpus anacardium Linn. nut milk extract in experimental inflammatory conditions","volume":"29","author":"Vanu","year":"2006","journal-title":"Biol. Pharm. Bull."},{"issue":"4","key":"10.1016\/j.bbrep.2019.100715_bib23","first-page":"99","article-title":"The phytochemical constituents, analgesic and anti-inflammatory effects of methanol extract of Jatropha curcas leaves in mice and Wister albino rats","volume":"12","author":"Uche","year":"2008","journal-title":"J. Appl. Sci. Environ. Manag."},{"issue":"1","key":"10.1016\/j.bbrep.2019.100715_bib24","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/S0378-8741(01)00172-6","article-title":"Antinociceptive and antiedematogenic effects of the aqueous extract of Hyptis pectinata leaves in experimental animals","volume":"76","author":"Obispo","year":"2001","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.bbrep.2019.100715_bib25","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/0014-2999(80)90377-5","article-title":"Release of prostaglandin E and F in an algogenic reaction and its inhibition","volume":"61","author":"Deraedt","year":"1980","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.bbrep.2019.100715_bib26","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0378-8741(00)00166-5","article-title":"Preliminary studies on the anti-inflammatory and analgesic activity of methanolic fraction of the root of Tragia involucrate","volume":"72","author":"Dhara","year":"2000","journal-title":"J. Ethnopharmacol."},{"issue":"4","key":"10.1016\/j.bbrep.2019.100715_bib27","doi-asserted-by":"crossref","first-page":"158","DOI":"10.4103\/0253-7613.56066","article-title":"Analgesic and anti-inflammatory activity of Argyreia speciosa roots","volume":"41","author":"Bachlav","year":"2009","journal-title":"Indian J. Pharmacol."},{"key":"10.1016\/j.bbrep.2019.100715_bib28","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1078\/0944-7113-00084","article-title":"Acute and chronic toxicity of Nigella sativa fixed oil","volume":"9","author":"Zaoui","year":"2002","journal-title":"Phytomedicine"},{"issue":"4","key":"10.1016\/j.bbrep.2019.100715_bib29","first-page":"99","article-title":"The phytochemical constituents, analgesic and anti-inflammatory effects of methanol extract of Jatropha curcas leaves in Mice and Wister albino rats","volume":"12","author":"Uche","year":"2008","journal-title":"Appl. Sci. Environ. Manage."},{"issue":"1","key":"10.1016\/j.bbrep.2019.100715_bib30","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.jneumeth.2005.03.002","article-title":"Baker yeast induced fever in young rats: characterization and validation of an animal model for antipyretics screening","volume":"147","author":"Tomazetti","year":"2005","journal-title":"J. Neurosci. Methods"},{"issue":"3","key":"10.1016\/j.bbrep.2019.100715_bib31","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1007\/s00011-009-0085-8","article-title":"Diacerein decreases TNF-?? and IL-1?? levels in peritoneal fluid and prevents Baker's yeast-induced fever in young rats","volume":"59","author":"Pasin","year":"2010","journal-title":"Inflamm. Res."},{"key":"10.1016\/j.bbrep.2019.100715_bib32","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1111\/j.1749-6632.1998.tb08316.x","article-title":"Cytokines and fever: mechanisms and sites of action","volume":"856","author":"Luheshi","year":"1998","journal-title":"Ann. NY Acad. Sci."},{"issue":"26","key":"10.1016\/j.bbrep.2019.100715_bib33","doi-asserted-by":"crossref","first-page":"1880","DOI":"10.1056\/NEJM199406303302609","article-title":"Theneurologic basis of fever","volume":"330","author":"Saper","year":"1994","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.bbrep.2019.100715_bib34","volume":"vols. 145\u2013167","author":"Veale","year":"1977"},{"issue":"4","key":"10.1016\/j.bbrep.2019.100715_bib35","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1016\/S0002-9343(01)00834-8","article-title":"Antipyretics: mechanisms of action and clinical use in fever suppression","volume":"111","author":"Aronoff","year":"2001","journal-title":"Am. J. Med."},{"key":"10.1016\/j.bbrep.2019.100715_bib36","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1254\/jphs.CRJ04003X","article-title":"Antiinflammatory plant flavonoids and cellular action mechanisms","volume":"96","author":"Kim","year":"2004","journal-title":"J. Pharmacol. Sci."},{"key":"10.1016\/j.bbrep.2019.100715_bib37","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1007\/s10787-009-0010-3","article-title":"Anti-inflammatory, analgesic and antipyretic activity of aqueous extract of fresh leaves of Coccinia indica","volume":"17","author":"Niazi","year":"2009","journal-title":"Inflammopharmacology"},{"issue":"1","key":"10.1016\/j.bbrep.2019.100715_bib38","first-page":"35","article-title":"Antiinflammatory and antipyretic activity of Aleuritis moluccana leaves","volume":"3","author":"Niazi","year":"2010","journal-title":"Asian J. Pharmaceut. Clin. Res."},{"issue":"2","key":"10.1016\/j.bbrep.2019.100715_bib39","first-page":"74","article-title":"Preliminary phytochemical analysis, HPTLC studies and antipyretic activity of alcohol and aqueous extract of Helicteres isora L. Root","volume":"2","author":"Tiwari","year":"2010","journal-title":"Int. J. Pharm. Pharm. Sci."},{"key":"10.1016\/j.bbrep.2019.100715_bib40","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1186\/s12906-015-0658-8","article-title":"Antipyretic, anti-inflammatory and analgesic activity of Acacia hydaspica R. Parker and its phytochemical analysis","volume":"15","author":"Afsar","year":"2015","journal-title":"BMC Complement Altern. Med."},{"issue":"1","key":"10.1016\/j.bbrep.2019.100715_bib41","doi-asserted-by":"crossref","first-page":"S382","DOI":"10.12980\/APJTB.4.2014C1020","article-title":"Antipyretic and antinociceptive activity of Diospyros lotus L. in animals","volume":"4","author":"Rauf","year":"2014","journal-title":"Asian Pac. J. Trop. Biomed."},{"issue":"36","key":"10.1016\/j.bbrep.2019.100715_bib42","first-page":"1","article-title":"In vivo and in vitro pharmacological activities of Tacca integrifolia rhizome and investigation of possible lead compounds against breast cancer through in silico approaches.","volume":"5","author":"Ahmed","year":"2019","journal-title":"Clin. Phytoscience."},{"issue":"2","key":"10.1016\/j.bbrep.2019.100715_bib43","first-page":"1","article-title":"In vivo neuroprotective, antinociceptive, anti-inflammatory potential in Swiss albino mice and in vitro antioxidant and clot lysis activities of fractionated Holigarna longifolia Roxb. bark extract","volume":"17","author":"Uddin","year":"2019","journal-title":"J. Complement. Integ. Med."},{"issue":"1","key":"10.1016\/j.bbrep.2019.100715_bib44","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1515\/jbcpp-2015-0056","article-title":"Evaluation of analgesic, anti-inflammatory, thrombolytic and hepatoprotective activities of roots of Premna esculenta (Roxb)","volume":"27","author":"Al Mahmud","year":"2016","journal-title":"J. Basic Clin. Physiol. Pharmacol."},{"issue":"24","key":"10.1016\/j.bbrep.2019.100715_bib45","first-page":"1","article-title":"Phytochemical investigations and antioxidant potential of leaf of Leea macrophylla (Roxb.)","volume":"10","author":"Al Mahmud","year":"2017","journal-title":"BMC Res. Notes."},{"issue":"1","key":"10.1016\/j.bbrep.2019.100715_bib46","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/S2221-1691(14)60202-1","article-title":"Phytopharmacological evaluation of ethanol extract of Sida cordifolia L. roots","volume":"4","author":"Momin","year":"2014","journal-title":"Asian Pacific J. Trop. Biomed."},{"issue":"5","key":"10.1016\/j.bbrep.2019.100715_bib47","first-page":"2069","article-title":"Sedative, anxiolytic and analgesic effects of Urena sinuata L. leaf extract in animal models","volume":"21","author":"Emran","year":"2014","journal-title":"Int. Food Res. J."}],"container-title":["Biochemistry and Biophysics Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405580819302432?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405580819302432?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T07:42:52Z","timestamp":1762501372000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2405580819302432"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3]]},"references-count":47,"alternative-id":["S2405580819302432"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrep.2019.100715","relation":{},"ISSN":["2405-5808"],"issn-type":[{"value":"2405-5808","type":"print"}],"subject":[],"published":{"date-parts":[[2020,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Pharmacological evidence for the use of Cissus assamica as a medicinal plant in the management of pain and pyrexia","name":"articletitle","label":"Article Title"},{"value":"Biochemistry and Biophysics Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbrep.2019.100715","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"100715"}}