{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T07:53:59Z","timestamp":1762502039285,"version":"build-2065373602"},"reference-count":27,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,2,21]],"date-time":"2023-02-21T00:00:00Z","timestamp":1676937600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100008771","name":"Animal and Plant Quarantine Agency","doi-asserted-by":"publisher","award":["B-1543085-22-24-01"],"award-info":[{"award-number":["B-1543085-22-24-01"]}],"id":[{"id":"10.13039\/501100008771","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100018749","name":"Korea Brain Research Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100018749","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003621","name":"Ministry of Science, ICT and Future Planning","doi-asserted-by":"publisher","award":["20-BR-02-19"],"award-info":[{"award-number":["20-BR-02-19"]}],"id":[{"id":"10.13039\/501100003621","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemistry and Biophysics Reports"],"published-print":{"date-parts":[[2023,7]]},"DOI":"10.1016\/j.bbrep.2023.101446","type":"journal-article","created":{"date-parts":[[2023,3,2]],"date-time":"2023-03-02T23:41:25Z","timestamp":1677800485000},"page":"101446","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Autoclave treatment fails to completely inactivate DLB alpha-synuclein seeding activity"],"prefix":"10.1016","volume":"34","author":[{"given":"Jung-Youn","family":"Han","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyung-Je","family":"Park","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hoo-Chang","family":"Park","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu-Ran","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roger A.","family":"Moore","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyun-Joo","family":"Sohn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9302-8664","authenticated-orcid":false,"given":"Young Pyo","family":"Choi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.bbrep.2023.101446_bib1","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1038\/nrneurol.2012.242","article-title":"100 years of Lewy pathology","volume":"9","author":"Goedert","year":"2013","journal-title":"Nat. Rev. Neurol."},{"issue":"1","key":"10.1016\/j.bbrep.2023.101446_bib2","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1007\/s00441-018-2814-1","article-title":"The concept of alpha-synuclein as a prion-like protein: ten years after","volume":"373","author":"Steiner","year":"2018","journal-title":"Cell Tissue Res."},{"issue":"23","key":"10.1016\/j.bbrep.2023.101446_bib3","doi-asserted-by":"crossref","first-page":"13363","DOI":"10.1073\/pnas.95.23.13363","article-title":"Prions","volume":"95","author":"Prusiner","year":"1998","journal-title":"Proc. Nat. Acad. Sci. USA."},{"issue":"21","key":"10.1016\/j.bbrep.2023.101446_bib4","doi-asserted-by":"crossref","first-page":"19213","DOI":"10.1074\/jbc.M110551200","article-title":"Biochemical characterization of the core structure of alpha-synuclein filaments","volume":"277","author":"Miake","year":"2002","journal-title":"J. Biol. Chem."},{"issue":"Suppl","key":"10.1016\/j.bbrep.2023.101446_bib5","doi-asserted-by":"crossref","first-page":"S69","DOI":"10.1016\/S0195-6701(99)90067-1","article-title":"Inactivation of prions by physical and chemical means","volume":"43","author":"Taylor","year":"1999","journal-title":"J. Hosp. Infect."},{"issue":"1","key":"10.1016\/j.bbrep.2023.101446_bib6","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1186\/s40478-018-0532-2","article-title":"Potent prion-like behaviors of pathogenic \u03b1-synuclein and evaluation of inactivation methods","volume":"6","author":"Tarutani","year":"2018","journal-title":"Acta Neuropathol. Commun."},{"issue":"1","key":"10.1016\/j.bbrep.2023.101446_bib7","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1007\/s00401-017-1762-2","article-title":"MSA prions exhibit remarkable stability and resistance to inactivation","volume":"135","author":"Woerman","year":"2018","journal-title":"Acta Neuropathol."},{"issue":"12","key":"10.1016\/j.bbrep.2023.101446_bib8","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1001217","article-title":"Rapid end-point quantitation of prion seeding activity with sensitivity comparable to bioassays","volume":"6","author":"Wilham","year":"2010","journal-title":"PLoS Pathog."},{"issue":"10","key":"10.1016\/j.bbrep.2023.101446_bib9","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1002\/acn3.338","article-title":"Alpha-synuclein RT-QuIC in the CSF of patients with alpha-synucleinopathies","volume":"3","author":"Fairfoul","year":"2016","journal-title":"Ann. Clin. Transl. Neurol."},{"issue":"1","key":"10.1016\/j.bbrep.2023.101446_bib10","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/s40478-018-0508-2","article-title":"Rapid and ultra-sensitive quantitation of disease-associated alpha-synuclein seeds in brain and cerebrospinal fluid by alphaSyn RT-QuIC","volume":"6","author":"Groveman","year":"2018","journal-title":"Acta Neuropathol. Commun."},{"issue":"1","key":"10.1016\/j.bbrep.2023.101446_bib11","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1080\/19336896.2020.1724608","article-title":"RT-QuIC-based detection of alpha-synuclein seeding activity in brains of dementia with Lewy Body patients and of a transgenic mouse model of synucleinopathy","volume":"14","author":"Han","year":"2020","journal-title":"Prion"},{"issue":"1","key":"10.1016\/j.bbrep.2023.101446_bib12","doi-asserted-by":"crossref","first-page":"7702","DOI":"10.1038\/s41598-021-87295-8","article-title":"Detection of chronic wasting disease in mule and white-tailed deer by RT-QuIC analysis of outer ear","volume":"11","author":"Ferreira","year":"2021","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bbrep.2023.101446_bib13","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.jhin.2020.10.018","article-title":"Alpha-synuclein seeds of Parkinson's disease show high prion-exceeding resistance to steam sterilization","volume":"108","author":"Pinder","year":"2021","journal-title":"J. Hosp. Infect."},{"issue":"6","key":"10.1016\/j.bbrep.2023.101446_bib14","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2113489119","article-title":"Different \u03b1-synuclein prion strains cause dementia with Lewy bodies and multiple system atrophy","volume":"119","author":"Ayers","year":"2022","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"issue":"1","key":"10.1016\/j.bbrep.2023.101446_bib15","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1038\/s41593-019-0541-x","article-title":"\u03b1-Synuclein strains target distinct brain regions and cell types","volume":"23","author":"Lau","year":"2020","journal-title":"Nat. Neurosci."},{"issue":"38","key":"10.1016\/j.bbrep.2023.101446_bib16","doi-asserted-by":"crossref","first-page":"E5308","DOI":"10.1073\/pnas.1514475112","article-title":"Evidence for \u03b1-synuclein prions causing multiple system atrophy in humans with parkinsonism","volume":"112","author":"Prusiner","year":"2015","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"issue":"7794","key":"10.1016\/j.bbrep.2023.101446_bib17","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1038\/s41586-020-1984-7","article-title":"Discriminating \u03b1-synuclein strains in Parkinson's disease and multiple system atrophy","volume":"578","author":"Shahnawaz","year":"2020","journal-title":"Nature"},{"issue":"1","key":"10.1016\/j.bbrep.2023.101446_bib18","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.mpdhp.2018.11.002","article-title":"Transmissible human proteopathies: an expanding field","volume":"25","author":"Jaunmuktane","year":"2019","journal-title":"Diagn. Histopathol."},{"issue":"2","key":"10.1016\/j.bbrep.2023.101446_bib19","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1097\/WCO.0000000000000672","article-title":"The prion-like propagation hypothesis in Alzheimer's and Parkinson's disease","volume":"32","author":"Duyckaerts","year":"2019","journal-title":"Curr. Opin. Neurol."},{"issue":"11","key":"10.1016\/j.bbrep.2023.101446_bib20","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1093\/jnen\/nlaa109","article-title":"Risk of transmissibility from neurodegenerative disease-associated proteins: experimental knowns and unknowns","volume":"79","author":"Asher","year":"2020","journal-title":"J. Neuropathol. Exp. Neurol."},{"issue":"9","key":"10.1016\/j.bbrep.2023.101446_bib21","doi-asserted-by":"crossref","first-page":"2469","DOI":"10.1007\/s11064-022-03566-4","article-title":"Transmission of cerebral \u03b2-amyloidosis among individuals","volume":"47","author":"Hamaguchi","year":"2022","journal-title":"Neurochem. Res."},{"issue":"10","key":"10.1016\/j.bbrep.2023.101446_bib22","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1016\/S1474-4422(20)30238-6","article-title":"Potential human transmission of amyloid \u03b2 pathology: surveillance and risks","volume":"19","author":"Lauwers","year":"2020","journal-title":"Lancet Neurol."},{"issue":"1","key":"10.1016\/j.bbrep.2023.101446_bib23","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1053\/tvjl.1999.0406","article-title":"Inactivation of transmissible degenerative encephalopathy agents: a review","volume":"159","author":"Taylor","year":"1997","journal-title":"Vet. J. (London, England"},{"issue":"9433","key":"10.1016\/j.bbrep.2023.101446_bib24","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/S0140-6736(04)16810-4","article-title":"Novel methods for disinfection of prion-contaminated medical devices","volume":"364","author":"Fichet","year":"2004","journal-title":"Lancet"},{"issue":"1","key":"10.1016\/j.bbrep.2023.101446_bib25","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1128\/JVI.80.1.322-331.2006","article-title":"Inactivation of prions by acidic sodium dodecyl sulfate","volume":"80","author":"Peretz","year":"2006","journal-title":"J. Virol."},{"issue":"11","key":"10.1016\/j.bbrep.2023.101446_bib26","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1000206","article-title":"Resistance of bovine spongiform encephalopathy (BSE) prions to inactivation","volume":"4","author":"Giles","year":"2008","journal-title":"PLoS Pathog."},{"issue":"9","key":"10.1016\/j.bbrep.2023.101446_bib27","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1005914","article-title":"Inactivation of prions and amyloid seeds with hypochlorous acid","volume":"12","author":"Hughson","year":"2016","journal-title":"PLoS Pathog."}],"container-title":["Biochemistry and Biophysics Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405580823000274?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405580823000274?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T07:49:33Z","timestamp":1762501773000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2405580823000274"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7]]},"references-count":27,"alternative-id":["S2405580823000274"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrep.2023.101446","relation":{},"ISSN":["2405-5808"],"issn-type":[{"type":"print","value":"2405-5808"}],"subject":[],"published":{"date-parts":[[2023,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Autoclave treatment fails to completely inactivate DLB alpha-synuclein seeding activity","name":"articletitle","label":"Article Title"},{"value":"Biochemistry and Biophysics Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbrep.2023.101446","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Korea Brain Research Institute, Animal and Plant Quarantine Agency. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"101446"}}