{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T07:53:43Z","timestamp":1762502023934,"version":"build-2065373602"},"reference-count":35,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T00:00:00Z","timestamp":1698710400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002951","name":"Dokkyo Medical University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002951","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemistry and Biophysics Reports"],"published-print":{"date-parts":[[2023,12]]},"DOI":"10.1016\/j.bbrep.2023.101575","type":"journal-article","created":{"date-parts":[[2023,11,8]],"date-time":"2023-11-08T06:22:35Z","timestamp":1699424555000},"page":"101575","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Utility of ultrasonography in a mouse model of non-alcoholic steatohepatitis induced by a choline-deficient, high-fat diet and dextran sulfate sodium"],"prefix":"10.1016","volume":"36","author":[{"given":"Fuki","family":"Hayakawa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2916-2268","authenticated-orcid":false,"given":"Koichi","family":"Soga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junko","family":"Fujino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takahiro","family":"Ota","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mayumi","family":"Yamaguchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5595-2330","authenticated-orcid":false,"given":"Masaya","family":"Tamano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrep.2023.101575_bib1","doi-asserted-by":"crossref","first-page":"1877","DOI":"10.1002\/hep.22848","article-title":"Increased intestinal permeability and tight junction alterations in nonalcoholic fatty liver disease","volume":"49","author":"Miele","year":"2009","journal-title":"Hepatology (Baltimore, Md"},{"key":"10.1016\/j.bbrep.2023.101575_bib2","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1002\/hep.28431","article-title":"Global epidemiology of nonalcoholic fatty liver disease-Meta-analytic assessment of prevalence, incidence, and outcomes","volume":"64","author":"Younossi","year":"2016","journal-title":"Hepatology (Baltimore, Md"},{"key":"10.1016\/j.bbrep.2023.101575_bib3","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1007\/s12072-021-10143-4","article-title":"The epidemiology of NAFLD and lean NAFLD in Japan: a meta-analysis with individual and forecasting analysis, 1995-2040","volume":"15","author":"Ito","year":"2021","journal-title":"Hepatology Int."},{"key":"10.1016\/j.bbrep.2023.101575_bib4","first-page":"521","article-title":"Clinical characteristics, surveillance, treatment allocation, and outcomes of non-alcoholic fatty liver disease-related hepatocellular carcinoma: a systematic review and meta-analysis, the Lancet","volume":"23","author":"Tan","year":"2022","journal-title":"Oncology"},{"key":"10.1016\/j.bbrep.2023.101575_bib5","doi-asserted-by":"crossref","first-page":"64","DOI":"10.4254\/wjh.v9.i1.64","article-title":"Shear wave elastography in hepatitis C patients before and after antiviral therapy","volume":"9","author":"Suda","year":"2017","journal-title":"World J. Hepatol."},{"key":"10.1016\/j.bbrep.2023.101575_bib6","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1111\/j.1872-034X.2011.00846.x","article-title":"Liver stiffness measured by transient elastography is a predictor of hepatocellular carcinoma development in viral hepatitis","volume":"41","author":"Akima","year":"2011","journal-title":"Hepatol. Res."},{"key":"10.1016\/j.bbrep.2023.101575_bib7","doi-asserted-by":"crossref","first-page":"1330","DOI":"10.1136\/gut.2007.126417","article-title":"Transient elastography in patients with non-alcoholic fatty liver disease (NAFLD)","volume":"56","author":"Yoneda","year":"2007","journal-title":"Gut"},{"key":"10.1016\/j.bbrep.2023.101575_bib8","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.bbrc.2015.12.012","article-title":"DSS colitis promotes tumorigenesis and fibrogenesis in a choline-deficient high-fat diet-induced NASH mouse model","volume":"470","author":"Achiwa","year":"2016","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbrep.2023.101575_bib9","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1136\/gut.2009.197822","article-title":"Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome","volume":"59","author":"Bauer","year":"2010","journal-title":"Gut"},{"key":"10.1016\/j.bbrep.2023.101575_bib10","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1016\/S0016-5085(98)70599-2","article-title":"Steatohepatitis: a tale of two \"hits\"?","volume":"114","author":"Day","year":"1998","journal-title":"Gastroenterology"},{"key":"10.1016\/j.bbrep.2023.101575_bib11","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1126\/science.1204265","article-title":"Human fatty liver disease: old questions and new insights","volume":"332","author":"Cohen","year":"2011","journal-title":"Science (New York, N.Y.)"},{"key":"10.1016\/j.bbrep.2023.101575_bib12","first-page":"459","article-title":"Histological and immunohistochemical assessment of liver biopsies in morbidly obese patients","volume":"27","author":"Caballero","year":"2012","journal-title":"Histol. Histopathol."},{"key":"10.1016\/j.bbrep.2023.101575_bib13","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1016\/j.jhep.2008.12.016","article-title":"Enhanced free cholesterol, SREBP-2 and StAR expression in human NASH","volume":"50","author":"Caballero","year":"2009","journal-title":"J. Hepatol."},{"key":"10.1016\/j.bbrep.2023.101575_bib14","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1038\/nrgastro.2010.191","article-title":"Animal models of nonalcoholic fatty liver disease","volume":"8","author":"Hebbard","year":"2011","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"10.1016\/j.bbrep.2023.101575_bib15","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/j.ccell.2014.09.003","article-title":"Metabolic activation of intrahepatic CD8+ T cells and NKT cells causes nonalcoholic steatohepatitis and liver cancer via cross-talk with hepatocytes","volume":"26","author":"Wolf","year":"2014","journal-title":"Cancer Cell"},{"key":"10.1016\/j.bbrep.2023.101575_bib16","doi-asserted-by":"crossref","first-page":"G518","DOI":"10.1152\/ajpgi.00024.2006","article-title":"Increased intestinal permeability in obese mice: new evidence in the pathogenesis of nonalcoholic steatohepatitis","volume":"292","author":"Brun","year":"2007","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"key":"10.1016\/j.bbrep.2023.101575_bib17","doi-asserted-by":"crossref","first-page":"1932","DOI":"10.1007\/s10620-012-2112-9","article-title":"Nutrition, intestinal permeability, and blood ethanol levels are altered in patients with nonalcoholic fatty liver disease (NAFLD)","volume":"57","author":"Volynets","year":"2012","journal-title":"Dig. Dis. Sci."},{"key":"10.1016\/j.bbrep.2023.101575_bib18","doi-asserted-by":"crossref","first-page":"1518","DOI":"10.1002\/hep.25500","article-title":"Toll-like receptor 4-dependent Kupffer cell activation and liver injury in a novel mouse model of parenteral nutrition and intestinal injury","volume":"55","author":"El Kasmi","year":"2012","journal-title":"Hepatology (Baltimore, Md"},{"key":"10.1016\/j.bbrep.2023.101575_bib19","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1016\/j.ccr.2012.02.007","article-title":"Promotion of hepatocellular carcinoma by the intestinal microbiota and TLR4","volume":"21","author":"Dapito","year":"2012","journal-title":"Cancer Cell"},{"key":"10.1016\/j.bbrep.2023.101575_bib20","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.cell.2009.12.052","article-title":"Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression","volume":"140","author":"Park","year":"2010","journal-title":"Cell"},{"key":"10.1016\/j.bbrep.2023.101575_bib21","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1053\/j.gastro.2005.06.061","article-title":"CpG motifs of bacterial DNA essentially contribute to the perpetuation of chronic intestinal inflammation","volume":"129","author":"Obermeier","year":"2005","journal-title":"Gastroenterology"},{"key":"10.1016\/j.bbrep.2023.101575_bib22","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1016\/0016-5085(90)90290-H","article-title":"A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in mice","volume":"98","author":"Okayasu","year":"1990","journal-title":"Gastroenterology"},{"key":"10.1016\/j.bbrep.2023.101575_bib23","doi-asserted-by":"crossref","first-page":"G1328","DOI":"10.1152\/ajpgi.00467.2004","article-title":"Acute colitis induced by dextran sulfate sodium progresses to chronicity in C57BL\/6 but not in BALB\/c mice: correlation between symptoms and inflammation","volume":"288","author":"Melgar","year":"2005","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"key":"10.1016\/j.bbrep.2023.101575_bib24","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1136\/gut.2007.147595","article-title":"Reduced mucin sulfonation and impaired intestinal barrier function in the hyposulfataemic NaS1 null mouse","volume":"58","author":"Dawson","year":"2009","journal-title":"Gut"},{"key":"10.1016\/j.bbrep.2023.101575_bib25","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1016\/j.jhep.2011.02.035","article-title":"DSS induced colitis increases portal LPS levels and enhances hepatic inflammation and fibrogenesis in experimental NASH","volume":"55","author":"G\u00e4bele","year":"2011","journal-title":"J. Hepatol."},{"key":"10.1016\/j.bbrep.2023.101575_bib26","doi-asserted-by":"crossref","first-page":"847","DOI":"10.14218\/JCTH.2021.00315","article-title":"Premorbid steatohepatitis increases the seriousness of dextran sulfate sodium-induced ulcerative colitis in mice","volume":"10","author":"Wang","year":"2022","journal-title":"J. Clin. Translation. Hepatol."},{"key":"10.1016\/j.bbrep.2023.101575_bib27","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1259\/0007-1285-52-615-184","article-title":"Ultrasound in the detection of chronic liver disease (the \"bright liver\")","volume":"52","author":"Joseph","year":"1979","journal-title":"Br. J. Radiol."},{"key":"10.1016\/j.bbrep.2023.101575_bib28","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1620\/tjem.139.43","article-title":"Ultrasonographical diagnosis of fatty liver: significance of the liver-kidney contrast","volume":"139","author":"Yajima","year":"1983","journal-title":"Tohoku J. Exp. Med."},{"key":"10.1016\/j.bbrep.2023.101575_bib29","doi-asserted-by":"crossref","first-page":"2708","DOI":"10.1111\/j.1572-0241.2007.01526.x","article-title":"The severity of ultrasonographic findings in nonalcoholic fatty liver disease reflects the metabolic syndrome and visceral fat accumulation","volume":"102","author":"Hamaguchi","year":"2007","journal-title":"Am. J. Gastroenterol."},{"key":"10.1016\/j.bbrep.2023.101575_bib30","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1053\/gast.2002.35354","article-title":"The utility of radiological imaging in nonalcoholic fatty liver disease","volume":"123","author":"Saadeh","year":"2002","journal-title":"Gastroenterology"},{"key":"10.1016\/j.bbrep.2023.101575_bib31","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.2214\/AJR.07.4047","article-title":"B-mode ultrasound with algorithm based on statistical analysis of signals: evaluation of liver fibrosis in patients with chronic hepatitis C","volume":"193","author":"Toyoda","year":"2009","journal-title":"Ajr. Am. J. Roentgenol."},{"issue":"2022","key":"10.1016\/j.bbrep.2023.101575_bib32","first-page":"253","article-title":"Role of liver stiffness measurements in patients who develop hepatocellular carcinoma after clearance of the hepatitis C virus","volume":"49","author":"Gyotoku","year":"2001","journal-title":"J. Med. Ultrason."},{"key":"10.1016\/j.bbrep.2023.101575_bib33","article-title":"Application of ultrasound and shear wave elastography imaging in a rat model of NAFLD\/NASH","volume":"170","author":"Morin","year":"2021","journal-title":"J. Vis. Exp."},{"key":"10.1016\/j.bbrep.2023.101575_bib34","doi-asserted-by":"crossref","first-page":"153","DOI":"10.3390\/gidisord4030015","article-title":"Shear-wave elastography using commercially available ultrasound in a mouse model of chronic liver disease","volume":"4","author":"Y","year":"2022","journal-title":"Gastroontest. Disord."},{"key":"10.1016\/j.bbrep.2023.101575_bib35","first-page":"8694","article-title":"A nude mouse model of orthotopic liver transplantation of human hepatocellular carcinoma HCCLM3 cell xenografts and the use of imaging to evaluate tumor progression","volume":"25","author":"Xu","year":"2019","journal-title":"Med. Sci. Mon. Int. Med. J. Exp. Clin. Res. : Int. Med. J. Exp. Clin. Res."}],"container-title":["Biochemistry and Biophysics Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405580823001565?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405580823001565?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T07:49:01Z","timestamp":1762501741000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2405580823001565"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12]]},"references-count":35,"alternative-id":["S2405580823001565"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrep.2023.101575","relation":{},"ISSN":["2405-5808"],"issn-type":[{"type":"print","value":"2405-5808"}],"subject":[],"published":{"date-parts":[[2023,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Utility of ultrasonography in a mouse model of non-alcoholic steatohepatitis induced by a choline-deficient, high-fat diet and dextran sulfate sodium","name":"articletitle","label":"Article Title"},{"value":"Biochemistry and Biophysics Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbrep.2023.101575","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"101575"}}