{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T22:22:19Z","timestamp":1785882139578,"version":"3.56.0"},"reference-count":26,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,7,25]],"date-time":"2025-07-25T00:00:00Z","timestamp":1753401600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100013217","name":"Hormozgan University of Medical Sciences Research Center for Molecular Medicine","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100013217","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemistry and Biophysics Reports"],"published-print":{"date-parts":[[2025,9]]},"DOI":"10.1016\/j.bbrep.2025.102180","type":"journal-article","created":{"date-parts":[[2025,7,28]],"date-time":"2025-07-28T20:32:59Z","timestamp":1753734779000},"page":"102180","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Molecular profiling of rheumatoid Arthritis: Expression dynamics of hsa_circ_0092125 and G6PD in an integrative gene expression study"],"prefix":"10.1016","volume":"43","author":[{"given":"Ahmad","family":"Golestanifar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hengameh","family":"Khedri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6343-8518","authenticated-orcid":false,"given":"Mohammadreza","family":"Saberiyan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arezo","family":"Masroor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrep.2025.102180_bib1","doi-asserted-by":"crossref","first-page":"3879","DOI":"10.2147\/IJGM.S353487","article-title":"Bioinformatics analysis identified the hub genes, mRNA-miRNA-lncRNA Axis, and signaling pathways involved in rheumatoid arthritis pathogenesis","volume":"15","author":"Yang","year":"2022","journal-title":"Int. J. Gen. Med."},{"issue":"8","key":"10.1016\/j.bbrep.2025.102180_bib2","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0160769","article-title":"Relationship between VEGF gene polymorphisms and serum VEGF protein levels in patients with rheumatoid arthritis","volume":"11","author":"Paradowska-Gorycka","year":"2016","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.bbrep.2025.102180_bib3","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1038\/s41598-018-37448-z","article-title":"High percentages and activity of synovial fluid NK cells present in patients with advanced stage active Rheumatoid Arthritis","volume":"9","author":"Yamin","year":"2019","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bbrep.2025.102180_bib4","article-title":"Biomarkers (mRNAs and non-coding RNAs) for the diagnosis and prognosis of rheumatoid arthritis","volume":"14","author":"Jiang","year":"2023","journal-title":"Front. Immunol."},{"issue":"1","key":"10.1016\/j.bbrep.2025.102180_bib5","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1080\/07853890.2023.2172605","article-title":"Long noncoding RNA\/circular RNA regulates competitive endogenous RNA networks in rheumatoid arthritis: molecular mechanisms and traditional Chinese medicine therapeutic significances","volume":"55","author":"Wen","year":"2023","journal-title":"Ann. Med."},{"key":"10.1016\/j.bbrep.2025.102180_bib6","article-title":"Current situation and trend of non-coding RNA in rheumatoid arthritis: a review and bibliometric analysis","volume":"14","author":"Wei","year":"2023","journal-title":"Front. Immunol."},{"issue":"8","key":"10.1016\/j.bbrep.2025.102180_bib7","doi-asserted-by":"crossref","first-page":"1350","DOI":"10.1016\/j.ymthe.2019.07.001","article-title":"Circular RNAs: a novel class of functional RNA molecules with a therapeutic perspective","volume":"27","author":"Santer","year":"2019","journal-title":"Mol. Ther."},{"key":"10.1016\/j.bbrep.2025.102180_bib8","article-title":"Biomarkers (mRNAs and non-coding RNAs) for the diagnosis and prognosis of rheumatoid arthritis","volume":"14","author":"Jiang","year":"2023","journal-title":"Front. Immunol."},{"issue":"3","key":"10.1016\/j.bbrep.2025.102180_bib9","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1016\/j.ijom.2019.07.014","article-title":"Down-regulation of hsa_circ_0092125 is related to the occurrence and development of oral squamous cell carcinoma","volume":"49","author":"Gao","year":"2020","journal-title":"Int. J. Oral Maxillofac. Surg."},{"issue":"1","key":"10.1016\/j.bbrep.2025.102180_bib10","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1093\/nar\/30.1.207","article-title":"Gene Expression Omnibus: NCBI gene expression and hybridization array data repository","volume":"30","author":"Edgar","year":"2002","journal-title":"Nucleic Acids Res."},{"issue":"7","key":"10.1016\/j.bbrep.2025.102180_bib11","doi-asserted-by":"crossref","DOI":"10.1093\/nar\/gkv007","article-title":"Limma powers differential expression analyses for RNA-sequencing and microarray studies","volume":"43","author":"Ritchie","year":"2015","journal-title":"Nucleic Acids Res."},{"issue":"W1","key":"10.1016\/j.bbrep.2025.102180_bib12","doi-asserted-by":"crossref","first-page":"W216","DOI":"10.1093\/nar\/gkac194","article-title":"DAVID: a web server for functional enrichment analysis and functional annotation of gene lists (2021 update)","volume":"50","author":"Sherman","year":"2022","journal-title":"Nucleic Acids Res."},{"issue":"Database issue","key":"10.1016\/j.bbrep.2025.102180_bib13","doi-asserted-by":"crossref","first-page":"D447","DOI":"10.1093\/nar\/gku1003","article-title":"STRING v10: protein-protein interaction networks, integrated over the tree of life","volume":"43","author":"Szklarczyk","year":"2015","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.bbrep.2025.102180_bib14","doi-asserted-by":"crossref","first-page":"S11","DOI":"10.1186\/1752-0509-8-S4-S11","article-title":"cytoHubba: identifying hub objects and sub-networks from complex interactome","volume":"8","author":"Chin","year":"2014","journal-title":"BMC Syst. Biol."},{"issue":"D1","key":"10.1016\/j.bbrep.2025.102180_bib15","doi-asserted-by":"crossref","first-page":"D83","DOI":"10.1093\/nar\/gkab809","article-title":"circMine: a comprehensive database to integrate, analyze and visualize human disease-related circRNA transcriptome","volume":"50","author":"Zhang","year":"2022","journal-title":"Nucleic Acids Res."},{"issue":"D1","key":"10.1016\/j.bbrep.2025.102180_bib16","doi-asserted-by":"crossref","first-page":"D92","DOI":"10.1093\/nar\/gkt1248","article-title":"starBase v2.0: decoding miRNA-ceRNA, miRNA-ncRNA and protein\u2013RNA interaction networks from large-scale CLIP-Seq data","volume":"42","author":"Li","year":"2013","journal-title":"Nucleic Acids Res."},{"issue":"11","key":"10.1016\/j.bbrep.2025.102180_bib17","doi-asserted-by":"crossref","first-page":"2498","DOI":"10.1101\/gr.1239303","article-title":"Cytoscape: a software environment for integrated models of biomolecular interaction networks","volume":"13","author":"Shannon","year":"2003","journal-title":"Genome Res."},{"issue":"11","key":"10.1016\/j.bbrep.2025.102180_bib18","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0294236","article-title":"SRplot: a free online platform for data visualization and graphing","volume":"18","author":"Tang","year":"2023","journal-title":"PLoS One"},{"issue":"10055","key":"10.1016\/j.bbrep.2025.102180_bib19","doi-asserted-by":"crossref","first-page":"2023","DOI":"10.1016\/S0140-6736(16)30173-8","article-title":"Rheumatoid arthritis","volume":"388","author":"Smolen","year":"2016","journal-title":"Lancet"},{"key":"10.1016\/j.bbrep.2025.102180_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2020.110617","article-title":"Dysregulation of non-coding RNAs in Rheumatoid arthritis","volume":"130","author":"Taheri","year":"2020","journal-title":"Biomed. Pharmacother."},{"issue":"1","key":"10.1016\/j.bbrep.2025.102180_bib21","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1007\/s10238-025-01589-z","article-title":"Integrative analysis of lncRNAs in rheumatoid arthritis: from bioinformatics to experimental validation","volume":"25","author":"Golestanifar","year":"2025","journal-title":"Clin. Exp. Med."},{"issue":"1","key":"10.1016\/j.bbrep.2025.102180_bib22","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1111\/imr.12838","article-title":"Immunometabolism in the development of rheumatoid arthritis","volume":"294","author":"Weyand","year":"2020","journal-title":"Immunol. Rev."},{"issue":"65","key":"10.1016\/j.bbrep.2025.102180_bib23","doi-asserted-by":"crossref","first-page":"109043","DOI":"10.18632\/oncotarget.22566","article-title":"G6PD promotes renal cell carcinoma proliferation through positive feedback regulation of p-STAT3","volume":"8","author":"Zhang","year":"2017","journal-title":"Oncotarget"},{"issue":"4","key":"10.1016\/j.bbrep.2025.102180_bib24","doi-asserted-by":"crossref","first-page":"612","DOI":"10.3109\/14397595.2013.851639","article-title":"Subclinical reduced G6PD activity in rheumatoid arthritis and Sj\u00f6gren's Syndrome patients: relation to clinical characteristics, disease activity and metabolic syndrome","volume":"24","author":"Gheita","year":"2014","journal-title":"Mod. Rheumatol."},{"issue":"6","key":"10.1016\/j.bbrep.2025.102180_bib25","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1002\/cai2.50","article-title":"Emerging roles of circular RNAs in the invasion and metastasis of head and neck cancer: possible functions and mechanisms","volume":"2","author":"Tang","year":"2023","journal-title":"Cancer Innov."},{"issue":"1","key":"10.1016\/j.bbrep.2025.102180_bib26","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1186\/s40164-022-00326-6","article-title":"G6PD promotes cell proliferation and dexamethasone resistance in multiple myeloma via increasing anti-oxidant production and activating Wnt\/\u03b2-catenin pathway","volume":"11","author":"Li","year":"2022","journal-title":"Exp. Hematol. Oncol."}],"container-title":["Biochemistry and Biophysics Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405580825002675?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405580825002675?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T14:29:39Z","timestamp":1767191379000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2405580825002675"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9]]},"references-count":26,"alternative-id":["S2405580825002675"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrep.2025.102180","relation":{},"ISSN":["2405-5808"],"issn-type":[{"value":"2405-5808","type":"print"}],"subject":[],"published":{"date-parts":[[2025,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Molecular profiling of rheumatoid Arthritis: Expression dynamics of hsa_circ_0092125 and G6PD in an integrative gene expression study","name":"articletitle","label":"Article Title"},{"value":"Biochemistry and Biophysics Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbrep.2025.102180","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"102180"}}