{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T20:16:04Z","timestamp":1793823364707,"version":"4.6.1"},"reference-count":25,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T00:00:00Z","timestamp":1775606400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002336","name":"Daiichi Sankyo Company","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002336","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemistry and Biophysics Reports"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.bbrep.2026.102587","type":"journal-article","created":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T08:16:59Z","timestamp":1776241019000},"page":"102587","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Integrated transcriptomic and proteomic validation identifies SLC35D3 as a tumor-selective surface antigen for colorectal and neuroendocrine carcinomas"],"prefix":"10.1016","volume":"46","author":[{"given":"Shunsuke","family":"Someya","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatsuya","family":"Inoue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reimi","family":"Kawaida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiaki","family":"Ohtsuka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keisuke","family":"Fukuchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrep.2026.102587_bib1","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2023.1113882","article-title":"The current landscape of CAR T-cell therapy for solid tumors: mechanisms, research progress, challenges, and counterstrategies","volume":"14","author":"Daei Sorkhabi","year":"2023","journal-title":"Front. Immunol."},{"key":"10.1016\/j.bbrep.2026.102587_bib2","doi-asserted-by":"crossref","first-page":"2824","DOI":"10.3390\/cancers15102824","article-title":"T-Cell engagers in solid cancers\u2014current landscape and future directions","volume":"15","author":"Shanshal","year":"2023","journal-title":"Cancers"},{"key":"10.1016\/j.bbrep.2026.102587_bib3","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1038\/s41571-021-00470-8","article-title":"Unlocking the potential of antibody\u2013drug conjugates for cancer therapy","volume":"18","author":"Drago","year":"2021","journal-title":"Nat. Rev. Clin. Oncol."},{"key":"10.1016\/j.bbrep.2026.102587_bib4","first-page":"85","article-title":"Dermatologic toxicity occurring during Anti-EGFR monoclonal inhibitor therapy in patients with metastatic colorectal cancer: a systematic review","volume":"17","author":"Lacouture","year":"2018","journal-title":"Clin. Colorectal Cancer"},{"key":"10.1016\/j.bbrep.2026.102587_bib5","doi-asserted-by":"crossref","first-page":"19","DOI":"10.3390\/cancers10010019","article-title":"EpCAM immunotherapy versus specific targeted delivery of drugs","volume":"10","author":"Macdonald","year":"2018","journal-title":"Cancers"},{"key":"10.1016\/j.bbrep.2026.102587_bib6","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1038\/mt.2010.24","article-title":"Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2","volume":"18","author":"Morgan","year":"2010","journal-title":"Mol. Ther."},{"key":"10.1016\/j.bbrep.2026.102587_bib7","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1038\/nature24277","article-title":"Genetic effects on gene expression across human tissues","volume":"550","year":"2017","journal-title":"Nature"},{"key":"10.1016\/j.bbrep.2026.102587_bib8","first-page":"68","article-title":"Review<br>The cancer genome atlas (TCGA): an immeasurable source of knowledge","volume":"2015","author":"Tomczak","year":"2015","journal-title":"Contemp. Oncol."},{"key":"10.1016\/j.bbrep.2026.102587_bib9","first-page":"233","article-title":"Colorectal cancer statistics, 2023","volume":"73","author":"Siegel","year":"2023","journal-title":"CA Cancer J. Clin."},{"key":"10.1016\/j.bbrep.2026.102587_bib10","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1158\/1535-7163.MCT-21-0599","article-title":"Novel Anti-LY6G6D\/CD3 T-Cell\u2013Dependent bispecific antibody for the treatment of colorectal cancer","volume":"21","author":"Wang","year":"2022","journal-title":"Mol. Cancer Therapeut."},{"key":"10.1016\/j.bbrep.2026.102587_bib11","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1004124","article-title":"Mutation of SLC35D3 causes metabolic syndrome by impairing dopamine signaling in striatal D1 neurons","volume":"10","author":"Zhang","year":"2014","journal-title":"PLoS Genet."},{"key":"10.1016\/j.bbrep.2026.102587_bib12","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.65417","article-title":"Localization, proteomics, and metabolite profiling reveal a putative vesicular transporter for UDP-Glucose","volume":"10","author":"Qian","year":"2021","journal-title":"eLife"},{"key":"10.1016\/j.bbrep.2026.102587_bib13","doi-asserted-by":"crossref","first-page":"7643","DOI":"10.1038\/s41467-023-43418-5","article-title":"SLC35D3 promotes white adipose tissue browning to ameliorate obesity by NOTCH signaling","volume":"14","author":"Wang","year":"2023","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bbrep.2026.102587_bib14","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1182\/blood-2006-08-040196","article-title":"The Slc35d3 gene, encoding an orphan nucleotide sugar transporter, regulates platelet-dense granules","volume":"109","author":"Chintala","year":"2006","journal-title":"Blood"},{"key":"10.1016\/j.bbrep.2026.102587_bib15","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1182\/blood-2011-11-389551","article-title":"SLC35D3 delivery from megakaryocyte early endosomes is required for platelet dense granule biogenesis and is differentially defective in hermansky-pudlak syndrome models","volume":"120","author":"Meng","year":"2012","journal-title":"Blood"},{"key":"10.1016\/j.bbrep.2026.102587_bib16","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1016\/j.csbj.2019.08.002","article-title":"Nucleotide sugar transporter SLC35 family structure and function","volume":"17","author":"Hadley","year":"2019","journal-title":"Comput. Struct. Biotechnol. J."},{"key":"10.1016\/j.bbrep.2026.102587_bib17","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1007\/s13402-022-00749-7","article-title":"Nucleotide sugar transporter SLC35A2 is involved in promoting hepatocellular carcinoma metastasis by regulating cellular glycosylation","volume":"46","author":"Cheng","year":"2023","journal-title":"Cell. Oncol."},{"key":"10.1016\/j.bbrep.2026.102587_bib18","doi-asserted-by":"crossref","first-page":"3295","DOI":"10.7150\/jca.84652","article-title":"Ablation of the GDP-Fucose transporter suppresses lung cancer cell proliferation and migration by reducing expression of PD-L1","volume":"14","author":"Zhang","year":"2023","journal-title":"J. Cancer"},{"key":"10.1016\/j.bbrep.2026.102587_bib19","doi-asserted-by":"crossref","first-page":"242","DOI":"10.3390\/biologics4030017","article-title":"Solute carrier family 35 (SLC35)\u2014An overview and recent progress","volume":"4","author":"Kamiyama","year":"2024","journal-title":"Biologics"},{"key":"10.1016\/j.bbrep.2026.102587_bib20","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1038\/s41392-024-01886-1","article-title":"Glycosylation: mechanisms, biological functions and clinical implications","volume":"9","author":"He","year":"2024","journal-title":"Signal Transduct. Targeted Ther."},{"key":"10.1016\/j.bbrep.2026.102587_bib21","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1016\/j.tcb.2024.09.006","article-title":"Sugar symphony: glycosylation in cancer metabolism and stemness","volume":"35","author":"Varadharaj","year":"2025","journal-title":"Trends Cell Biol."},{"key":"10.1016\/j.bbrep.2026.102587_bib22","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1002\/ijc.34718","article-title":"qRT-PCR analysis of CEACAM5, KLK6, SLC35D3, MUC2 and POSTN in colon cancer lymph nodes\u2014An improved method for assessment of tumor stage and prognosis","volume":"154","author":"Lindmark","year":"2024","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.bbrep.2026.102587_bib23","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1002\/prm2.12108","article-title":"Solute carrier family 35 member D3 promotes colorectal cancer progression through AMPK signaling pathway","volume":"12","author":"Wang","year":"2023","journal-title":"Precision Medical Sciences"},{"key":"10.1016\/j.bbrep.2026.102587_bib24","doi-asserted-by":"crossref","first-page":"2662","DOI":"10.1038\/npp.2014.121","article-title":"Cellular and behavioral outcomes of dorsal striatonigral neuron ablation: new insights into striatal functions","volume":"39","author":"R\u00e9vy","year":"2014","journal-title":"Neuropsychopharmacol"},{"key":"10.1016\/j.bbrep.2026.102587_bib25","doi-asserted-by":"crossref","DOI":"10.1200\/OA.0000000000000001","article-title":"Small cell lung cancer: new hope, new challenges","author":"Desai","year":"2024","journal-title":"JCO Oncol Adv"}],"container-title":["Biochemistry and Biophysics Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405580826001470?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405580826001470?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T23:38:46Z","timestamp":1781739526000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2405580826001470"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":25,"alternative-id":["S2405580826001470"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrep.2026.102587","relation":{},"ISSN":["2405-5808"],"issn-type":[{"value":"2405-5808","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Integrated transcriptomic and proteomic validation identifies SLC35D3 as a tumor-selective surface antigen for colorectal and neuroendocrine carcinomas","name":"articletitle","label":"Article Title"},{"value":"Biochemistry and Biophysics Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbrep.2026.102587","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"102587"}}