{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T16:44:28Z","timestamp":1786985068432,"version":"build-2736575974"},"reference-count":20,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2004,1,1]],"date-time":"2004-01-01T00:00:00Z","timestamp":1072915200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2004,1,1]],"date-time":"2004-01-01T00:00:00Z","timestamp":1072915200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Blood Cells, Molecules, and Diseases"],"published-print":{"date-parts":[[2004,1]]},"DOI":"10.1016\/j.bcmd.2003.11.001","type":"journal-article","created":{"date-parts":[[2003,12,17]],"date-time":"2003-12-17T05:43:04Z","timestamp":1071639784000},"page":"124-130","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"title":["A novel mutation in the glucose-6-phosphate dehydrogenase gene in a subject with chronic nonspherocytic hemolytic anemia\u2014characterization of enzyme using yeast expression system and molecular modeling"],"prefix":"10.1016","volume":"32","author":[{"given":"Dorota","family":"Grabowska","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ewa","family":"Jablonska-Skwiecinska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danuta","family":"Plochocka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Chelstowska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irmina","family":"Lewandowska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iwona","family":"Witos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zofia","family":"Majewska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roma","family":"Rokicka-Milewska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beata","family":"Burzynska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bcmd.2003.11.001_BIB1","doi-asserted-by":"crossref","first-page":"3613","DOI":"10.1182\/blood.V84.11.3613.bloodjournal84113613","article-title":"G6PD deficiency","volume":"11","author":"Beutler","year":"1994","journal-title":"Blood"},{"key":"10.1016\/j.bcmd.2003.11.001_BIB2","first-page":"137","article-title":"The genetics of glucose-6-phosphate dehydrogenase deficiency","volume":"27","author":"Beutler","year":"1990","journal-title":"Semin. Hematol."},{"key":"10.1016\/j.bcmd.2003.11.001_BIB3","doi-asserted-by":"crossref","first-page":"2810","DOI":"10.1073\/pnas.77.5.2810","article-title":"Localization of loci for hypoxanthine phosphoribosyltransferase and glucose-6-phosphate dehydrogenase and biochemical evidence of nonrandom X chromosome expression from studies of a human X-autosome translocation","volume":"77","author":"Pai","year":"1980","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.bcmd.2003.11.001_BIB4","unstructured":"Online Mendelian Inheritance in Man, OMIM (TM). McKusick-Nathans Institute for Genetic Medicine, Johns Hopkins University (Baltimore, MD) and National Center for Biotechnology Information, National Library of Medicine (Bethesda, MD) (2000) World Wide Web URL: http:\/\/www.ncbi.nlm.nih.gov\/omim\/."},{"key":"10.1016\/j.bcmd.2003.11.001_BIB5","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1128\/jb.95.4.1267-1271.1968","article-title":"Selection of Escherichia coli mutants lacking glucose-6-phosphate dehydrogenase or gluconate-6-phosphate dehydrogenase","volume":"95","author":"Fraenkel","year":"1968","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.bcmd.2003.11.001_BIB6","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/0378-1119(90)90248-P","article-title":"Isolation and characterization of the ZWF1 gene of Saccharomyces cerevisiae, encoding glucose-6-phosphate dehydrogenase","volume":"96","author":"Nogae","year":"1990","journal-title":"Gene"},{"key":"10.1016\/j.bcmd.2003.11.001_BIB7","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1002\/j.1460-2075.1991.tb07981.x","article-title":"Identification of the structural gene for glucose-6-phosphate dehydrogenase in yeast. Inactivation leads to a nutritional requirement for organic sulphur","volume":"10","author":"Thomas","year":"1991","journal-title":"EMBO J."},{"key":"10.1016\/j.bcmd.2003.11.001_BIB8","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/S0969-2126(00)00104-0","article-title":"Human glucose-6-phosphate dehydrogenase: the crystal structure reveals a structural NADP+ molecule and provides insights into enzyme deficiency","volume":"8","author":"Au","year":"2000","journal-title":"Structure"},{"key":"10.1016\/j.bcmd.2003.11.001_BIB9","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1016\/S0969-2126(94)00110-3","article-title":"The three-dimensional structure of glucose 6-phosphate dehydrogenase from Leuconostoc mesenteroides refined at 2.0 \u00c5","volume":"2","author":"Rowland","year":"1994","journal-title":"Structure"},{"key":"10.1016\/j.bcmd.2003.11.001_BIB10","doi-asserted-by":"crossref","first-page":"13984","DOI":"10.1074\/jbc.M210076200","article-title":"The ALD6 gene product is indispensable for providing NADPH in yeast cells lacking glucose-6-phosphate dehydrogenase activity","volume":"278","author":"Grabowska","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bcmd.2003.11.001_BIB11","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/S0076-6879(02)50957-5","article-title":"Transformation of yeast by lithium acetate\/single-stranded carrier DNA\/polyethylene glycol method","volume":"350","author":"Gietz","year":"2002","journal-title":"Methods Enzymol."},{"key":"10.1016\/j.bcmd.2003.11.001_BIB12","doi-asserted-by":"crossref","first-page":"4705","DOI":"10.1002\/j.1460-2075.1992.tb05575.x","article-title":"Isolation and characterization of a sucrose carrier cDNA from spinach by functional expression in yeast","volume":"11","author":"Riesmeier","year":"1992","journal-title":"EMBO J."},{"key":"10.1016\/j.bcmd.2003.11.001_BIB13","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/0378-1119(89)90358-2","article-title":"Site-directed mutagenesis by overlap extension using the polymerase chain reaction","volume":"77","author":"Ho","year":"1989","journal-title":"Gene"},{"key":"10.1016\/j.bcmd.2003.11.001_BIB14","first-page":"62","article-title":"Red cell metabolism\u2014A manual of biochemical methods","author":"Beutler","year":"1971"},{"key":"10.1016\/j.bcmd.2003.11.001_BIB15","first-page":"177","article-title":"Heterogeneity of glucose-6-phosphate dehydrogenase enzymopathies in the GDR","volume":"46","author":"Jacobash","year":"1987","journal-title":"Biomed. Biochim. Acta"},{"key":"10.1016\/j.bcmd.2003.11.001_BIB16","doi-asserted-by":"crossref","first-page":"10015","DOI":"10.1073\/pnas.86.24.10015","article-title":"Identification of the binding domain for NADP+ of human glucose-6-phosphate dehydrogenase by sequence analysis of mutants","volume":"86","author":"Hirono","year":"1989","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.bcmd.2003.11.001_BIB17","doi-asserted-by":"crossref","first-page":"1436","DOI":"10.1182\/blood.V83.5.1436.1436","article-title":"Expression and biochemical characterization of human glucose-6-phosphate dehydrogenase in Escherichia coli: a system to analyze normal and mutant enzymes","volume":"83","author":"Tang","year":"1994","journal-title":"Blood"},{"key":"10.1016\/j.bcmd.2003.11.001_BIB18","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/0378-1119(89)90239-4","article-title":"Functional expression of human glucose-6-phosphate dehydrogenase in Escherichia coli","volume":"78","author":"Persico","year":"1989","journal-title":"Gene"},{"key":"10.1016\/j.bcmd.2003.11.001_BIB19","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/0167-4838(92)90237-8","article-title":"Purification and properties of human glucose-6-phosphate dehydrogenase made in E. coli","volume":"1119","author":"Bautista","year":"1992","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bcmd.2003.11.001_BIB20","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1111\/j.1432-1033.1988.tb14435.x","article-title":"The production of normal and variant human glucose-6-phosphate dehydrogenase in cos cells","volume":"178","author":"Mason","year":"1988","journal-title":"Eur. J. Biochem."}],"container-title":["Blood Cells, Molecules, and Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1079979603002833?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1079979603002833?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T12:21:10Z","timestamp":1761049270000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1079979603002833"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,1]]},"references-count":20,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2004,1]]}},"alternative-id":["S1079979603002833"],"URL":"https:\/\/doi.org\/10.1016\/j.bcmd.2003.11.001","relation":{},"ISSN":["1079-9796"],"issn-type":[{"value":"1079-9796","type":"print"}],"subject":[],"published":{"date-parts":[[2004,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A novel mutation in the glucose-6-phosphate dehydrogenase gene in a subject with chronic nonspherocytic hemolytic anemia\u2014characterization of enzyme using yeast expression system and molecular modeling","name":"articletitle","label":"Article Title"},{"value":"Blood Cells, Molecules, and Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bcmd.2003.11.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"converted-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2003 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}