{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T21:16:17Z","timestamp":1778793377382,"version":"3.51.4"},"reference-count":36,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2006,3,1]],"date-time":"2006-03-01T00:00:00Z","timestamp":1141171200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2006,3,1]],"date-time":"2006-03-01T00:00:00Z","timestamp":1141171200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Blood Cells, Molecules, and Diseases"],"published-print":{"date-parts":[[2006,3]]},"DOI":"10.1016\/j.bcmd.2005.12.003","type":"journal-article","created":{"date-parts":[[2006,2,8]],"date-time":"2006-02-08T13:25:23Z","timestamp":1139405123000},"page":"255-258","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"title":["Prevalence of \u2212\u03b13.7 and \u03b1\u03b1\u03b1anti3.7 alleles in sickle cell trait and \u03b2-thalassemia patients in Mexico"],"prefix":"10.1016","volume":"36","author":[{"given":"Mar\u00eda Paulina","family":"Nava","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bertha","family":"Ibarra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda Teresa","family":"Maga\u00f1a","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda","family":"de la Luz Ch\u00e1vez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F. Javier","family":"Perea","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bcmd.2005.12.003_bib1","series-title":"A Syllabus of Thalassemia Mutations","author":"Huisman","year":"1997"},{"key":"10.1016\/j.bcmd.2005.12.003_bib2","first-page":"4571","article-title":"The hemoglobinopathies","volume":"vol. III","author":"Weatherall","year":"2001"},{"key":"10.1016\/j.bcmd.2005.12.003_bib3","first-page":"53","article-title":"Alpha-thalassaemia","volume":"vol. 11, no. 1","author":"Bernini","year":"1998"},{"key":"10.1016\/j.bcmd.2005.12.003_bib4","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1002\/ajh.20083","article-title":"High frequency of deletional \u03b1-thalassemia in \u03b2-thalassemia trait: implications for genetic counseling","volume":"76","author":"Panigrahi","year":"2004","journal-title":"Am. J. Hematol."},{"key":"10.1016\/j.bcmd.2005.12.003_bib5","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.bcmd.2003.12.005","article-title":"A rare example that coinheritance of a severe form of beta-thalassemia and alpha thalassemia interact in a \u201csynergistic\u201d manner to balance the phenotype of classic thalassemic syndromes","volume":"32","author":"Kanavakis","year":"2004","journal-title":"Blood Cells Mol. Diseases"},{"key":"10.1016\/j.bcmd.2005.12.003_bib6","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1081\/HEM-120035917","article-title":"Thalassemia intermedia due to co-inheritance of beta(0)\/beta(+)-thalassemia and (- - SEA) alpha-thalassemia\/Hb Westmead [alpha 122 (H 5) His\u00a0>\u00a0Gln (alpha2) in a Chinese family","volume":"2","author":"Wong","year":"2004","journal-title":"Hemoglobin"},{"key":"10.1016\/j.bcmd.2005.12.003_bib7","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1038\/nm1022","article-title":"Antisickling effects of an endogenous human alpha-like globin","volume":"4","author":"He","year":"2004","journal-title":"Nat. Med."},{"key":"10.1016\/j.bcmd.2005.12.003_bib8","first-page":"217","article-title":"Abnormal hemoglobins in northwestern Mexico","volume":"6","author":"Ibarra","year":"1982","journal-title":"Acta Anthropog."},{"key":"10.1016\/j.bcmd.2005.12.003_bib9","first-page":"163","article-title":"Hemoglobinas anormales y talasemias en la Rep\u00fablica Mexicana","volume":"50","author":"Ruiz-Reyes","year":"1998","journal-title":"Rev. Invest. Clin."},{"key":"10.1016\/j.bcmd.2005.12.003_bib10","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1006\/bcmd.2002.0498","article-title":"Analysis of beta S and beta A genes in a Mexican population with African roots","volume":"28","author":"Maga\u00f1a","year":"2002","journal-title":"Blood Cell Mol. Dis."},{"key":"10.1016\/j.bcmd.2005.12.003_bib11","first-page":"395","article-title":"Alpha-thalassemia in a selected population of Mexico","volume":"50","author":"Casas-Casta\u00f1eda","year":"1998","journal-title":"Rev. Invest. Clin."},{"key":"10.1016\/j.bcmd.2005.12.003_bib12","doi-asserted-by":"crossref","first-page":"1879","DOI":"10.1182\/blood.V95.5.1879","article-title":"A single tube multiplex PCR method to detect the common \u03b1+ thalassemia alleles","volume":"195","author":"Shaji","year":"2000","journal-title":"Blood"},{"key":"10.1016\/j.bcmd.2005.12.003_bib13","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1002\/(SICI)1096-8652(199611)53:3<202::AID-AJH11>3.0.CO;2-F","article-title":"Detection of alpha-thalassaemia-2 (3.7 kb) anti corresponding triplication (alpha) (alpha) (alpha) (anti3.7 kb) by PCR: an improved technical change","volume":"53","author":"Smetanina","year":"1996","journal-title":"Am. J. Hematol."},{"key":"10.1016\/j.bcmd.2005.12.003_bib14","first-page":"300","article-title":"Detection of common deletional alpha-thalassaemia-2 determinants by PCR","volume":"88","author":"Baysal","year":"1994","journal-title":"Am. J. Hematol."},{"key":"10.1016\/j.bcmd.2005.12.003_bib15","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1159\/000022899","article-title":"\u03b1-Thalassemia in Bantu Population from Congo-Brazzaville: its interaction with sickle cell anemia","volume":"50","author":"Mou\u00e9l\u00e9","year":"2000","journal-title":"Hum. Hered."},{"key":"10.1016\/j.bcmd.2005.12.003_bib16","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1159\/000040863","article-title":"Alpha-thalassemia in the United Arab Emirates","volume":"100","author":"El-Kalla","year":"1998","journal-title":"Acta Haematol."},{"key":"10.1016\/j.bcmd.2005.12.003_bib17","first-page":"273","article-title":"Hemoglobin anomalies at the university hospital center in Lome","volume":"25","author":"Segbena","year":"2001","journal-title":"Togo. Hemoglobin"},{"key":"10.1016\/j.bcmd.2005.12.003_bib18","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1111\/j.1600-0609.1987.tb00013.x","article-title":"Alpha-thalassaemia in Nigeria: its interaction with sickle-cell disease","volume":"38","author":"Falusi","year":"1987","journal-title":"Eur. J. Haematol."},{"key":"10.1016\/j.bcmd.2005.12.003_bib19","first-page":"377","article-title":"Beta S-haplotypes and alpha-thalassemia along the coast belt of Kenya","volume":"66","author":"Ojwang","year":"1989","journal-title":"East Afr. Med. J."},{"key":"10.1016\/j.bcmd.2005.12.003_bib20","doi-asserted-by":"crossref","first-page":"171","DOI":"10.3109\/03630260008997525","article-title":"Hb Bart's levels in cord blood and alpha-thalassemia mutations in Cyprus","volume":"24","author":"Kyriacou","year":"2000","journal-title":"Hemoglobin"},{"key":"10.1016\/j.bcmd.2005.12.003_bib21","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1046\/j.1365-2141.2003.04346.x","article-title":"The molecular basis for the thalassemias in Sri Lanka","volume":"121","author":"Fisher","year":"2003","journal-title":"Br. J. Haematol."},{"key":"10.1016\/j.bcmd.2005.12.003_bib22","doi-asserted-by":"crossref","first-page":"252","DOI":"10.3109\/03630269509005826","article-title":"Molecular basis of alpha-thalassemia in Portugal","volume":"19","author":"Peres","year":"1995","journal-title":"Hemoglobin"},{"key":"10.1016\/j.bcmd.2005.12.003_bib23","first-page":"51","article-title":"Rapid detection of alpha+ thalassaemia deletion and alpha-globin gene triplication by Gap-PCR in Indian subjects","volume":"62","author":"Agarwal","year":"2002","journal-title":"Med. Trop."},{"key":"10.1016\/j.bcmd.2005.12.003_bib24","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1007\/s002770050528","article-title":"Prevalence study and molecular characterization of alpha-thalassemia in Filipinos","volume":"78","author":"Ko","year":"1999","journal-title":"Ann. Hematol."},{"key":"10.1016\/j.bcmd.2005.12.003_bib25","first-page":"121","article-title":"Molecular diagnosis of beta-thalassemia intermedia","volume":"48","author":"Chen","year":"1998","journal-title":"Hum. Hered."},{"key":"10.1016\/j.bcmd.2005.12.003_bib26","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1007\/BF00273068","article-title":"High frequency of triplicated \u03b1-globin loci and absence or low frequency of \u03b1 thalassemia in Polynesian Samoans","volume":"70","author":"Lie-Injo","year":"1985","journal-title":"Hum. Genet."},{"key":"10.1016\/j.bcmd.2005.12.003_bib27","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1002\/ajh.2830220307","article-title":"Sickle cell anemia associated with \u03b1-thalassemia in Malaysian Indians","volume":"22","author":"Lie-Injo","year":"1986","journal-title":"Am. J. Hematol."},{"key":"10.1016\/j.bcmd.2005.12.003_bib28","first-page":"726","article-title":"Association of hemoglobinopathies S and alpha thalassemia. Study of 45 patients","volume":"124","author":"Gonzalez","year":"2005","journal-title":"Med. Clin. (Barcelona)"},{"key":"10.1016\/j.bcmd.2005.12.003_bib29","first-page":"171","article-title":"Clinical phenotype of triplicated alpha-globin genes and heterozygosity for beta0-thalassemia in Chinese subjects","volume":"8","author":"Ma","year":"2001","journal-title":"Int. J. Mol. Med."},{"key":"10.1016\/j.bcmd.2005.12.003_bib30","first-page":"514","article-title":"The prevalence of beta-thalassemia heterozygotes compound alpha-thalassemia in Guangdong district","volume":"22","author":"Han","year":"2001","journal-title":"Zhonghua Xueyexue Zazhi"},{"key":"10.1016\/j.bcmd.2005.12.003_bib31","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1007\/s00277-003-0738-6","article-title":"Triplication (\/\u03b1\u03b1\u03b1anti3.7) or deletion (\/\u2212\u03b13.7) association in Argentinean \u03b2-thalassemic carriers","volume":"11","author":"Bragos","year":"2003","journal-title":"Ann. Hematol."},{"key":"10.1016\/j.bcmd.2005.12.003_bib32","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1590\/S0102-311X2005000400032","article-title":"Clinical, hematological, and molecular characterization of sickle cell anemia pediatric patients from two different cities in Brasil","volume":"21","author":"Menezes Lyra","year":"2005","journal-title":"Cad. Saude Publica"},{"key":"10.1016\/j.bcmd.2005.12.003_bib33","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1111\/j.1365-2141.2005.05704.x","article-title":"The frequency of the sickle allele in Jamaica has no declined over the last 22 years","volume":"130","author":"Hanchard","year":"2005","journal-title":"Br. J. Haematol."},{"key":"10.1016\/j.bcmd.2005.12.003_bib34","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1111\/j.1365-2141.1986.tb04117.x","article-title":"Haemoglobin gene frequencies in the Jamaican population: a study in 100,000 newborns","volume":"64","author":"Serjeant","year":"1986","journal-title":"Br. J. Haematol."},{"key":"10.1016\/j.bcmd.2005.12.003_bib35","first-page":"535","article-title":"Alpha-globin gene haplotypes in South American Indians","volume":"67","author":"Zago","year":"1995","journal-title":"Hum. Biol."},{"key":"10.1016\/j.bcmd.2005.12.003_bib36","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1081\/HEM-100105220","article-title":"The thalassemia syndromes: molecular characterization in the Spanish population","volume":"25","author":"Villegas","year":"2001","journal-title":"Hemoglobin"}],"container-title":["Blood Cells, Molecules, and Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1079979605002147?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1079979605002147?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T12:23:37Z","timestamp":1761049417000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1079979605002147"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,3]]},"references-count":36,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2006,3]]}},"alternative-id":["S1079979605002147"],"URL":"https:\/\/doi.org\/10.1016\/j.bcmd.2005.12.003","relation":{},"ISSN":["1079-9796"],"issn-type":[{"value":"1079-9796","type":"print"}],"subject":[],"published":{"date-parts":[[2006,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prevalence of \u2212\u03b13.7 and \u03b1\u03b1\u03b1anti3.7 alleles in sickle cell trait and \u03b2-thalassemia patients in Mexico","name":"articletitle","label":"Article Title"},{"value":"Blood Cells, Molecules, and Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bcmd.2005.12.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2006 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}