{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T17:59:09Z","timestamp":1790099949895,"version":"4.0.1"},"reference-count":21,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2012,2,1]],"date-time":"2012-02-01T00:00:00Z","timestamp":1328054400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,2,1]],"date-time":"2012-02-01T00:00:00Z","timestamp":1328054400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Blood Cells, Molecules, and Diseases"],"published-print":{"date-parts":[[2012,2]]},"DOI":"10.1016\/j.bcmd.2011.12.001","type":"journal-article","created":{"date-parts":[[2011,12,24]],"date-time":"2011-12-24T00:35:45Z","timestamp":1324686945000},"page":"86-90","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":40,"title":["Development and evaluation of a reverse dot blot assay for the simultaneous detection of common alpha and beta thalassemia in Chinese"],"prefix":"10.1016","volume":"48","author":[{"given":"Min","family":"Lin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan-Juan","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Long-Xu","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun-Li","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun-Fang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tian-Yu","family":"Zhong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei-Chen","family":"Pan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiao-Ren","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying-Fang","family":"Wen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gui-Rong","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-Fen","family":"Zhan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fen","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li-Ye","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bcmd.2011.12.001_bb0005","first-page":"5","article-title":"Alpha-thalassaemia","volume":"28","author":"Harteveld","year":"2010","journal-title":"Orphanet J. Rare Dis."},{"key":"10.1016\/j.bcmd.2011.12.001_bb0010","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1136\/jmg.24.10.578","article-title":"Disorders of haemoglobin in China","volume":"24","author":"Zeng","year":"1987","journal-title":"J. Med. Genet."},{"key":"10.1016\/j.bcmd.2011.12.001_bb0015","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1111\/j.1399-0004.2007.00791.x","article-title":"Current status of thalassemia in minority populations in Guangxi, China","volume":"71","author":"Pan","year":"2007","journal-title":"Clin. Genet."},{"key":"10.1016\/j.bcmd.2011.12.001_bb0020","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1136\/jcp.2003.014456","article-title":"The prevalence and spectrum of alpha and beta thalassaemia in Guangdong Province: implications for the future health burden and population screening","volume":"57","author":"Xu","year":"2004","journal-title":"J. Clin. Pathol."},{"key":"10.1016\/j.bcmd.2011.12.001_bb0025","first-page":"659","article-title":"Detection of deletional determinants of alpha-thalassemia in Li people in Hainan province by a single tube multiplex polymerase chain reaction method","volume":"84","author":"Liu","year":"2004","journal-title":"Zhonghua Ya Yi Xue Hui Za Zhi"},{"key":"10.1016\/j.bcmd.2011.12.001_bb0030","first-page":"104","article-title":"Biochemical screening and genetic diagnosis of thalassemia in children from Kunming","volume":"13","author":"Wen","year":"2011","journal-title":"Zhongguo Dang Dai Er Ke Za Zhi"},{"key":"10.1016\/j.bcmd.2011.12.001_bb0035","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1182\/blood.V95.1.360","article-title":"Single-tube multiplex-PCR screen for common deletional determinants of alpha-thalassemia","volume":"95","author":"Chong","year":"2000","journal-title":"Blood"},{"key":"10.1016\/j.bcmd.2011.12.001_bb0040","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1046\/j.1365-2141.1999.01221.x","article-title":"A reverse dot-blot method for rapid detection of non-deletion alpha thalassaemia","volume":"104","author":"Chan","year":"1999","journal-title":"Br. J. Haematol."},{"key":"10.1016\/j.bcmd.2011.12.001_bb0045","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1002\/humu.1380030110","article-title":"Reverse dot blot probes for the screening of beta-thalassemia mutations in Asians and American blacks","volume":"3","author":"Cai","year":"1994","journal-title":"Hum. Mutat."},{"key":"10.1016\/j.bcmd.2011.12.001_bb0050","doi-asserted-by":"crossref","first-page":"2503","DOI":"10.1093\/nar\/17.7.2503","article-title":"Analysis of any point mutation in DNA. The amplification refractory mutation system (ARMS)","volume":"17","author":"Newton","year":"1989","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.bcmd.2011.12.001_bb0055","first-page":"6","article-title":"Restriction fragment length polymorphism of the human beta-globin gene cluster: analysis of a beta-thalassemic family in Taiwan","volume":"10","author":"Ma","year":"1986","journal-title":"Proc. Natl. Sci. Counc. Repub. China B."},{"key":"10.1016\/j.bcmd.2011.12.001_bb0060","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1002\/humu.20036","article-title":"PAP: detection of ultra rare mutations depends on P* oligonucleotides: \u201csleeping beauties\u201d awakened by the kiss of pyrophosphorolysis","volume":"23","author":"Liu","year":"2004","journal-title":"Hum. Mutat."},{"key":"10.1016\/j.bcmd.2011.12.001_bb0065","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/j.clinbiochem.2008.02.008","article-title":"Rapid genotyping of known mutations and polymorphisms in beta-globin gene based on the DHPLC profile patterns of homoduplexes and heteroduplexes","volume":"41","author":"Li","year":"2008","journal-title":"Clin. Biochem."},{"key":"10.1016\/j.bcmd.2011.12.001_bb0070","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1128\/JCM.00989-09","article-title":"Evaluation of a newly developed GenoArray human papillomavirus (HPV) genotyping assay and comparison with the Roche Linear Array HPV genotyping assay","volume":"48","author":"Liu","year":"2010","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.bcmd.2011.12.001_bb0075","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.bcmd.2008.09.005","article-title":"Hb G-Waimanalo: occurrence in combination with alpha-thalassemia-1 Southeast Asian deletion","volume":"42","author":"Lin","year":"2009","journal-title":"Blood Cells Mol. Dis."},{"key":"10.1016\/j.bcmd.2011.12.001_bb0080","article-title":"Prevalence and molecular characterization of abnormal hemoglobin in eastern Guangdong of southern China","author":"Lin","year":"2011","journal-title":"Clin. Genet."},{"key":"10.1016\/j.bcmd.2011.12.001_bb0085","doi-asserted-by":"crossref","first-page":"1667","DOI":"10.1016\/j.clinbiochem.2009.07.017","article-title":"Rapid identification of HBB gene mutations by high-resolution melting analysis","volume":"42","author":"Shih","year":"2009","journal-title":"Clin. Biochem."},{"key":"10.1016\/j.bcmd.2011.12.001_bb0090","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/j.jmoldx.2011.03.005","article-title":"A melting curve analysis-based PCR assay for one-step genotyping of \u03b2-thalassemia mutations a multicenter validation","volume":"13","author":"Xiong","year":"2011","journal-title":"J. Mol. Diagn."},{"key":"10.1016\/j.bcmd.2011.12.001_bb0095","first-page":"1010","article-title":"Simultaneous detection of alpha-thalassemia and beta-thalassemia by oligonucleotide microarray","volume":"89","author":"Ye","year":"2004","journal-title":"Haematologica"},{"key":"10.1016\/j.bcmd.2011.12.001_bb0100","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jbiotec.2004.07.016","article-title":"Oligonucleotide array for detection of common severe determinants of alpha thalassemia","volume":"115","author":"Ye","year":"2005","journal-title":"J. Biotechnol."},{"key":"10.1016\/j.bcmd.2011.12.001_bb0105","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1111\/j.1479-828X.2008.00844.x","article-title":"Genital human papillomavirus screening by gene chip in Chinese women of Guangdong province","volume":"48","author":"Lin","year":"2008","journal-title":"Aust. N. Z. J. Obstet. Gynaecol."}],"container-title":["Blood Cells, Molecules, and Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1079979611002361?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1079979611002361?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T12:28:19Z","timestamp":1761049699000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1079979611002361"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,2]]},"references-count":21,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2012,2]]}},"alternative-id":["S1079979611002361"],"URL":"https:\/\/doi.org\/10.1016\/j.bcmd.2011.12.001","relation":{},"ISSN":["1079-9796"],"issn-type":[{"value":"1079-9796","type":"print"}],"subject":[],"published":{"date-parts":[[2012,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Development and evaluation of a reverse dot blot assay for the simultaneous detection of common alpha and beta thalassemia in Chinese","name":"articletitle","label":"Article Title"},{"value":"Blood Cells, Molecules, and Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bcmd.2011.12.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}