{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T00:12:08Z","timestamp":1791331928982,"version":"4.3.1"},"reference-count":84,"publisher":"Elsevier BV","issue":"2-3","content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Blood Cells, Molecules, and Diseases"],"published-print":{"date-parts":[[2014,2]]},"DOI":"10.1016\/j.bcmd.2013.09.004","type":"journal-article","created":{"date-parts":[[2013,10,10]],"date-time":"2013-10-10T06:03:10Z","timestamp":1381384990000},"page":"126-133","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":70,"title":["Interleukin-6 directly impairs the erythroid development of human TF-1 erythroleukemic cells"],"prefix":"10.1016","volume":"52","author":[{"given":"Bryan J.","family":"McCranor","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min Jung","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole M.","family":"Cruz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian-Li","family":"Xue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan E.","family":"Berger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeremy D.","family":"Walston","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Curt I.","family":"Civin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cindy N.","family":"Roy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bcmd.2013.09.004_bb0005","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1056\/NEJMra041809","article-title":"Anemia of chronic disease","volume":"352","author":"Weiss","year":"2005","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0010","doi-asserted-by":"crossref","first-page":"2263","DOI":"10.1182\/blood-2004-05-1812","article-title":"Prevalence of anemia in persons 65years and older in the United States: evidence for a high rate of unexplained anemia","volume":"104","author":"Guralnik","year":"2004","journal-title":"Blood"},{"key":"10.1016\/j.bcmd.2013.09.004_bb0015","doi-asserted-by":"crossref","first-page":"1714","DOI":"10.1001\/jama.281.18.1714","article-title":"The definition of anemia in older persons","volume":"281","author":"Izaks","year":"1999","journal-title":"JAMA"},{"key":"10.1016\/j.bcmd.2013.09.004_bb0020","doi-asserted-by":"crossref","first-page":"1400","DOI":"10.1001\/archinte.163.12.1400","article-title":"Anemia: not just an innocent bystander?","volume":"163","author":"Nissenson","year":"2003","journal-title":"JAMA Intern. Med."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0025","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/S0093-7754(01)90214-3","article-title":"Prevalence of anemia in cancer patients undergoing radiation therapy","volume":"28","author":"Harrison","year":"2001","journal-title":"Semin. Oncol."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0030","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1007\/s40265-013-0018-2","article-title":"Targeting interleukin-6 in rheumatoid arthritis","volume":"73","author":"Md Yusof","year":"2013","journal-title":"Drugs"},{"key":"10.1016\/j.bcmd.2013.09.004_bb0035","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1038\/nrrheum.2012.183","article-title":"Anaemia in inflammatory rheumatic diseases","volume":"9","author":"Weiss","year":"2013","journal-title":"Nat. Rev. Rheumatol."},{"issue":"Suppl. 8","key":"10.1016\/j.bcmd.2013.09.004_bb0040","first-page":"viii17","article-title":"Anaemia and inflammation: what are the implications for the nephrologist?","volume":"18","author":"Stenvinkel","year":"2003","journal-title":"Nephrol. Dial. Transplant."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0045","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1159\/000328037","article-title":"Renal anemia of inflammation: the name is self-explanatory","volume":"32","author":"Yilmaz","year":"2011","journal-title":"Blood Purif."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0050","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1182\/blood.V91.1.301","article-title":"Epidemiology of anemia in human immunodeficiency virus (HIV)-infected persons: results from the multistate adult and adolescent spectrum of HIV disease surveillance project","volume":"91","author":"Sullivan","year":"1998","journal-title":"Blood"},{"key":"10.1016\/j.bcmd.2013.09.004_bb0055","doi-asserted-by":"crossref","first-page":"2214","DOI":"10.1001\/archinte.165.19.2214","article-title":"A prospective study of anemia status, hemoglobin concentration, and mortality in an elderly cohort: the Cardiovascular Health Study","volume":"165","author":"Zakai","year":"2005","journal-title":"Arch. Intern. Med."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0060","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1007\/BF03324741","article-title":"Hemoglobin concentrations in 358 apparently healthy 80-year-old Danish men and women. Should the reference interval be adjusted for age?","volume":"20","author":"Milman","year":"2008","journal-title":"Aging Clin. Exp. Res."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0065","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1093\/gerona\/59.3.M249","article-title":"Hemoglobin levels and skeletal muscle: results from the InCHIANTI study","volume":"59","author":"Cesari","year":"2004","journal-title":"J. Gerontol. A Biol. Sci. Med. Sci."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0070","doi-asserted-by":"crossref","first-page":"3841","DOI":"10.1182\/blood-2005-10-4308","article-title":"Impact of anemia on hospitalization and mortality in older adults","volume":"107","author":"Culleton","year":"2006","journal-title":"Blood"},{"key":"10.1016\/j.bcmd.2013.09.004_bb0075","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1093\/gerona\/61.5.474","article-title":"Anemia in old age is associated with increased mortality and hospitalization","volume":"61","author":"Penninx","year":"2006","journal-title":"J. Gerontol. A Biol. Sci. Med. Sci."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0080","doi-asserted-by":"crossref","first-page":"2009","DOI":"10.1016\/j.jacc.2004.01.038","article-title":"Hemoglobin level is an independent predictor for adverse cardiovascular outcomes in women undergoing evaluation for chest pain: results from the National Heart, Lung, and Blood Institute Women's Ischemia Syndrome Evaluation Study","volume":"43","author":"Arant","year":"2004","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0085","doi-asserted-by":"crossref","first-page":"2713","DOI":"10.1161\/CIRCULATIONAHA.105.577577","article-title":"Hemoglobin level, chronic kidney disease, and the risks of death and hospitalization in adults with chronic heart failure","volume":"113","author":"Go","year":"2006","journal-title":"Circulation"},{"key":"10.1016\/j.bcmd.2013.09.004_bb0090","doi-asserted-by":"crossref","first-page":"2214","DOI":"10.1002\/1097-0142(20010615)91:12<2214::AID-CNCR1251>3.0.CO;2-P","article-title":"Anemia as an independent prognostic factor for survival in patients with cancer","volume":"91","author":"Caro","year":"2001","journal-title":"Cancer"},{"key":"10.1016\/j.bcmd.2013.09.004_bb0095","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1046\/j.1532-5415.2002.50313.x","article-title":"Looking at the relationship between hemoglobin concentration and prevalent mobility difficulty in older women. Should the criteria currently used to define anemia in older people be reevaluated?","volume":"50","author":"Chaves","year":"2002","journal-title":"J. Am. Geriatr. Soc."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0100","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.1111\/j.1532-5415.2006.00863.x","article-title":"Association between mild anemia and executive function impairment in community-dwelling older women: the Women's Health and Aging Study II","volume":"54","author":"Chaves","year":"2006","journal-title":"J. Am. Geriatr. Soc."},{"issue":"9","key":"10.1016\/j.bcmd.2013.09.004_bb0425","doi-asserted-by":"crossref","first-page":"1604","DOI":"10.1111\/j.1532-5415.2009.02400.x","article-title":"Anemia and 9-year domain-specific cognitive decline in community-dwelling older women: the Women's Health and Aging Study II","volume":"57","author":"Deal","year":"2009","journal-title":"J. Am. Geriatr. Soc."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0110","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1093\/annonc\/mdg167","article-title":"Control of cancer-related anemia with erythropoietic agents: a review of evidence for improved quality of life and clinical outcomes","volume":"14","author":"Cella","year":"2003","journal-title":"Ann. Oncol."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0115","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1634\/theoncologist.5-suppl_2-19","article-title":"The relationship between anemia and quality of life in cancer patients","volume":"5","author":"Sabbatini","year":"2000","journal-title":"Oncologist"},{"key":"10.1016\/j.bcmd.2013.09.004_bb0120","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.amjmed.2003.12.008","article-title":"Prevalence and outcomes of anemia in cancer: a systematic review of the literature","volume":"116","author":"Knight","year":"2004","journal-title":"Am. J. Med."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0125","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.bcmd.2008.04.005","article-title":"Aging and erythropoiesis: current state of knowledge","volume":"41","author":"Price","year":"2008","journal-title":"Blood Cells Mol. Dis."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0130","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1093\/gerona\/glr090","article-title":"Unexplained anemia predominates despite an intensive evaluation in a racially diverse cohort of older adults from a referral anemia clinic","volume":"66","author":"Artz","year":"2011","journal-title":"J. Gerontol. A Biol. Sci. Med. Sci."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0135","doi-asserted-by":"crossref","first-page":"1849","DOI":"10.3324\/haematol.2010.023101","article-title":"Prevalence, incidence and types of mild anemia in the elderly: the \u201cHealth and Anemia\u201d population-based study","volume":"95","author":"Tettamanti","year":"2010","journal-title":"Haematologica"},{"key":"10.1016\/j.bcmd.2013.09.004_bb0140","doi-asserted-by":"crossref","first-page":"4757","DOI":"10.1038\/sj.onc.1209606","article-title":"Mitochondria in hematopoiesis and hematological diseases","volume":"25","author":"Fontenay","year":"2006","journal-title":"Oncogene"},{"key":"10.1016\/j.bcmd.2013.09.004_bb0145","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/j.cbpa.2013.01.010","article-title":"Heme transport and erythropoiesis","volume":"17","author":"Yaun","year":"2013","journal-title":"Curr. Opin. Chem. Biol."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0150","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1097\/MOH.0b013e328351c48b","article-title":"Heme metabolism and erythropoiesis","volume":"19","author":"Chung","year":"2012","journal-title":"Curr. Opin. Hematol."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0430","article-title":"Evidence of mitochondrial dysfunction and impaired ROS detoxifying machinery in Fanconi anemia cells","author":"Kumari","year":"2013","journal-title":"Oncogene"},{"key":"10.1016\/j.bcmd.2013.09.004_bb0160","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.freeradbiomed.2013.01.015","article-title":"From clinical description, to in vitro and animal studies, and backward to patients: oxidative stress and mitochondrial dysfunction in Fanconi anemia","volume":"58","author":"Pagano","year":"2013","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0165","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1007\/s12185-010-0688-4","article-title":"Hereditary sideroblastic anemia: pathophysiology and gene mutations","volume":"92","author":"Harigae","year":"2010","journal-title":"Int. J. Hematol."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0170","doi-asserted-by":"crossref","first-page":"4045","DOI":"10.1182\/blood-2008-08-169474","article-title":"Erythriod dysplasia, megaloblastic anemia, and impaired lymphopoiesis arising from mitochondrial dysfunction","volume":"114","author":"Chen","year":"2009","journal-title":"Blood"},{"key":"10.1016\/j.bcmd.2013.09.004_bb0175","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1007\/s10863-012-9465-9","article-title":"Mitochondrial dysfunction and cancer metastasis","volume":"44","author":"Chen","year":"2012","journal-title":"J. Bioenerg. Biomembr."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0180","doi-asserted-by":"crossref","first-page":"1396","DOI":"10.1016\/j.clinbiochem.2008.08.072","article-title":"Mitochondrial depolarisation and oxidative stress in rheumatoid arthritis patients","volume":"41","author":"Moodley","year":"2008","journal-title":"Clin. Biochem."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0435","doi-asserted-by":"crossref","DOI":"10.1186\/1471-2164-10-388","article-title":"Mitochondrial dysregulation and oxidative stress in patients with chronic kidney disease","volume":"10","author":"Granata","year":"2009","journal-title":"BMC Genomics"},{"key":"10.1016\/j.bcmd.2013.09.004_bb0190","doi-asserted-by":"crossref","first-page":"192","DOI":"10.18632\/aging.100546","article-title":"A novel diagnostic tool reveals mitochondrial pathology in human diseases and aging","volume":"5","author":"Scheibye-Knudsen","year":"2013","journal-title":"Aging (Albany NY)"},{"key":"10.1016\/j.bcmd.2013.09.004_bb0195","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1172\/JCI64125","article-title":"The role of mitochondria in aging","volume":"123","author":"Bratic","year":"2013","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0440","doi-asserted-by":"crossref","DOI":"10.1016\/j.joca.2006.03.008","article-title":"Mitochondrial activity is modulated by TNF\u03b1 and IL-1\u03b2 in normal human chondrocyte cells","volume":"14","author":"Lopez-Armada","year":"2006","journal-title":"Osteoarthr. Cartil."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0205","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1097\/00000658-199211000-00003","article-title":"Tumor necrosis factor alpha inhibits hepatocyte mitochondrial respiration","volume":"216","author":"Stadler","year":"1992","journal-title":"Ann. Surg."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0210","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1023\/A:1006896832582","article-title":"TNF\u03b1 and IL-1\u03b1 inhibit both pyruvate dehydrogenase activity and mitochondrial function in cardiomyocytes: evidence for primary impairment of mitochondrial function","volume":"177","author":"Zell","year":"1997","journal-title":"Mol. Cell. Biochem."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0215","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/j.ejphar.2011.08.033","article-title":"Epigallocatechin-3-gallate protects pro-inflammatory cytokine induced injuries in insulin-producing cells through the mitochondrial pathway","volume":"670","author":"Zhang","year":"2011","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0220","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1007\/s10863-011-9361-8","article-title":"IL-6 induces lipolysis and mitochondrial dysfunction, but does not affect insulin-mediated glucose transport in 3T3-L1 adipocytes","volume":"43","author":"Ji","year":"2011","journal-title":"J. Bioenerg. Biomembr."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0225","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.1002\/eji.201141436","article-title":"Mitochondria: sovereign of inflammation?","volume":"41","author":"Tschopp","year":"2011","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0230","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.mito.2013.01.003","article-title":"Mitochondrial dysfunction and the inflammatory response","volume":"13","author":"Lopez-Armada","year":"2013","journal-title":"Mitochondrion"},{"key":"10.1016\/j.bcmd.2013.09.004_bb0235","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1042\/CS20110340","article-title":"IL-6\/IL-6 receptor system and its role in physiological and pathological conditions","volume":"122","author":"Mihara","year":"2012","journal-title":"Clin. Sci. (Lond.)"},{"issue":"Suppl. 2","key":"10.1016\/j.bcmd.2013.09.004_bb0445","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1186\/ar1917","article-title":"Interleukin-6 and chronic inflammation","volume":"8","author":"Gabay","year":"2006","journal-title":"Arthritis Res. Ther."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0245","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/S1471-4906(02)00013-3","article-title":"IL-6: a regulator of the transition from neutrophil to monocyte recruitment during inflammation","volume":"24","author":"Kaplanski","year":"2003","journal-title":"Trends Immunol."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0250","first-page":"380","article-title":"Anemia in early rheumatoid arthritis is associated with interleukin 6-mediated bone marrow suppression, but has no effect on disease course or mortality","volume":"35","author":"Nikolaisen","year":"2008","journal-title":"J. Rheumatol."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0255","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1136\/ard.2004.022681","article-title":"Raised levels of interleukin 6 in systemic lupus erythematosus correlate with anaemia","volume":"64","author":"Ripley","year":"2005","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0260","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1007\/BF01714900","article-title":"Serum levels of interleukin-6 in multiple myeloma and other hematological disorders: correlation with disease activity and other prognostic parameters","volume":"62","author":"Nachbaur","year":"1991","journal-title":"Ann. Hematol."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0265","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1182\/blood-2005-01-0160","article-title":"Hemoglobin levels correlate with interleukin-6 levels in patients with advanced untreated epithelial ovarian cancer: role of inflammation in cancer-related anemia","volume":"106","author":"Maccio","year":"2005","journal-title":"Blood"},{"key":"10.1016\/j.bcmd.2013.09.004_bb0270","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.1046\/j.1532-5415.2002.50315.x","article-title":"Serum interleukin-6 and hemoglobin as physiological correlates in the geriatric syndrome of frailty: a pilot study","volume":"50","author":"Leng","year":"2002","journal-title":"J. Am. Geriatr. Soc."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0275","doi-asserted-by":"crossref","first-page":"2461","DOI":"10.1182\/blood-2002-10-3235","article-title":"Hepcidin, a putative mediator of anemia of inflammation, is a type II acute-phase protein","volume":"101","author":"Nemeth","year":"2003","journal-title":"Blood"},{"key":"10.1016\/j.bcmd.2013.09.004_bb0280","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1172\/JCI200420945","article-title":"IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin","volume":"113","author":"Nemeth","year":"2004","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0285","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1182\/asheducation-2010.1.276","article-title":"Anemia of inflammation","volume":"2010","author":"Roy","year":"2010","journal-title":"Hematol. Am. Soc. Hematol. Educ. Progr."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0290","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1182\/blood.V86.3.900.900","article-title":"Recombinant human interleukin-6 induces a rapid and reversible anemia in cancer patients","volume":"86","author":"Nieken","year":"1995","journal-title":"Blood"},{"key":"10.1016\/j.bcmd.2013.09.004_bb0295","doi-asserted-by":"crossref","first-page":"1288","DOI":"10.1182\/blood.V86.4.1288.bloodjournal8641288","article-title":"Interleukin-6-associated anemia: determination of the underlying mechanism","volume":"86","author":"Atkins","year":"1995","journal-title":"Blood"},{"key":"10.1016\/j.bcmd.2013.09.004_bb0300","doi-asserted-by":"crossref","first-page":"20030","DOI":"10.1074\/jbc.272.32.20030","article-title":"Globin gene silencing in primary erythroid cultures. An inhibitory role for interleukin-6","volume":"272","author":"Ferry","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0305","doi-asserted-by":"crossref","first-page":"1648","DOI":"10.3324\/haematol.2011.053397","article-title":"Late stage erythroid precursor production is impaired in mice with chronic inflammation","volume":"97","author":"Prince","year":"2012","journal-title":"Haematologica"},{"key":"10.1016\/j.bcmd.2013.09.004_bb0310","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1002\/jcp.1041400219","article-title":"Establishment and characterization of a unique human cell line that proliferates dependently on GM-CSF, IL-3, or erythropoietin","volume":"140","author":"Kitamura","year":"1989","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0315","doi-asserted-by":"crossref","first-page":"17413","DOI":"10.1073\/pnas.0909296106","article-title":"Resolving the distinct stages in erythroid differentiation based on dynamic changes in membrane protein expression during erythropoiesis","volume":"106","author":"Chen","year":"2009","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0320","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1186\/1471-2105-7-85","article-title":"Statistical analysis of real-time PCR data","volume":"7","author":"Yuan","year":"2006","journal-title":"BMC Bioinforma."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0325","doi-asserted-by":"crossref","first-page":"3261","DOI":"10.1182\/blood.V98.12.3261","article-title":"Ineffective erythropoiesis in Stat5a(\u2212\/\u2212)5b(\u2212\/\u2212) mice due to decreased survival of early erythroblasts","volume":"98","author":"Socolovsky","year":"2001","journal-title":"Blood"},{"key":"10.1016\/j.bcmd.2013.09.004_bb0330","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1139\/O10-146","article-title":"Anion exchanger 1 in red blood cells and kidney: band 3's in a pod","volume":"89","author":"Wu","year":"2011","journal-title":"Biochem. Cell Biol."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0335","doi-asserted-by":"crossref","first-page":"4425","DOI":"10.1182\/blood.V93.12.4425","article-title":"The expression of human blood group antigens during erythropoiesis in a cell culture system","volume":"93","author":"Southcott","year":"1999","journal-title":"Blood"},{"key":"10.1016\/j.bcmd.2013.09.004_bb0340","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1002\/cyto.a.20033","article-title":"Efficacy of MitoTracker Green and CMXrosamine to measure changes in mitochondrial membrane potentials in living cells and tissues","volume":"61","author":"Pendergrass","year":"2004","journal-title":"Cytometry A"},{"key":"10.1016\/j.bcmd.2013.09.004_bb0345","doi-asserted-by":"crossref","first-page":"S96","DOI":"10.2337\/diabetes.53.2007.S96","article-title":"Roles of mitochondria in health and disease","volume":"53","author":"Duchen","year":"2004","journal-title":"Diabetes"},{"key":"10.1016\/j.bcmd.2013.09.004_bb0350","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/S0006-3495(88)83158-8","article-title":"Membrane potential can be determined in individual cells from the nernstian distribution of cationic dyes","volume":"53","author":"Ehrenberg","year":"1988","journal-title":"Biophys. J."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0355","doi-asserted-by":"crossref","first-page":"12579","DOI":"10.1073\/pnas.91.26.12579","article-title":"Physiological cytosolic Ca2+ transients evoke concurrent mitochondrial depolarizations","volume":"91","author":"Loew","year":"1994","journal-title":"PNAS"},{"issue":"9","key":"10.1016\/j.bcmd.2013.09.004_bb0450","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1016\/j.jcma.2013.05.004","article-title":"Plasma levels in sepsis patients of annexin A1, lipoxin A4, macrophage inflammatory protein-3a, and neutrophil gelatinase-associated lipocalin","volume":"76","author":"Tsai","year":"2013","journal-title":"J. Clin. Med. Assoc."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0365","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1007\/s005920050147","article-title":"Circulating levels of interleukin-6, its soluble receptor and interleukin-6\/interleukin-6 receptor complexes in patients with type 2 diabetes mellitus","volume":"36","author":"Kado","year":"1999","journal-title":"Acta Diabetol."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0370","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1007\/s12032-012-0363-0","article-title":"Lack of correlation between angiogenic cytokines and serum insulin-like growth factor-1 in patients with multiple myeloma","volume":"30","author":"Pappa","year":"2013","journal-title":"Med. Oncol."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0375","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1007\/s00277-012-1470-x","article-title":"B cell-activating factor: its clinical significance in multiple myeloma patients","volume":"91","author":"Fraqioudaki","year":"2012","journal-title":"Ann. Hematol."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0380","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1007\/s10156-008-0608-1","article-title":"Usefulness of procalcitonin serum level for the discrimination of severe sepsis from sepsis: a multicenter prospective study","volume":"14","author":"Endo","year":"2008","journal-title":"J. Infect. Chemother."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0385","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1111\/j.1348-0421.2012.00488.x","article-title":"Plasma leukocyte cell-derived chemotaxin 2 is associated with the severity of systemic inflammation in patients with sepsis","volume":"56","author":"Ando","year":"2012","journal-title":"Microbiol. Immunol."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0390","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.cyto.2004.10.010","article-title":"Sequential measurement of IL-6 blood levels in patients with systemic inflammatory response syndrome (SIRS)\/sepsis","volume":"29","author":"Oda","year":"2005","journal-title":"Cytokine"},{"key":"10.1016\/j.bcmd.2013.09.004_bb0395","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1038\/ng1137","article-title":"Cell-specific mitotic defect and dyserythropoiesis associated with erythriod band 3 deficiency","volume":"34","author":"Paw","year":"2003","journal-title":"Nat. Genet."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0400","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1083\/jcb.200809125","article-title":"Parkin is recruited selectively to impaired mitochondria and promotes their autophagy","volume":"183","author":"Narendra","year":"2008","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0405","doi-asserted-by":"crossref","first-page":"18989","DOI":"10.1074\/jbc.274.27.18989","article-title":"Mechanism of iron transport to the site of heme synthesis inside yeast mitochondria","volume":"274","author":"Lange","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0410","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/S0014-2999(01)01291-2","article-title":"The iron chelator pyridoxal isonicotinoyl hydrazone inhibits mitochondrial lipid peroxidation induced by Fe(II)-citrate","volume":"428","author":"Santos","year":"2001","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.bcmd.2013.09.004_bb0415","doi-asserted-by":"crossref","first-page":"1644","DOI":"10.1002\/hep.22498","article-title":"Translocation or iron from lysosomes into mitochondria is a key event during oxidative stress-induced hepatocellular injury","volume":"48","author":"Uchiyama","year":"2008","journal-title":"Hepatology"},{"key":"10.1016\/j.bcmd.2013.09.004_bb0420","doi-asserted-by":"crossref","first-page":"1802","DOI":"10.1046\/j.1471-4159.1999.0721802.x","article-title":"Mitochondrial iron sequestration in dopamine-challenged astroglia: role of heme oxygenase-1 and the permeability transition pore","volume":"72","author":"Schipper","year":"1999","journal-title":"J. Neurochem."}],"updated-by":[{"DOI":"10.1016\/j.bcmd.2014.02.001","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2014,4,1]],"date-time":"2014-04-01T00:00:00Z","timestamp":1396310400000}}],"container-title":["Blood Cells, Molecules, and Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1079979613002088?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1079979613002088?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,8,5]],"date-time":"2020-08-05T16:37:45Z","timestamp":1596645465000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1079979613002088"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,2]]},"references-count":84,"journal-issue":{"issue":"2-3","published-print":{"date-parts":[[2014,2]]}},"alternative-id":["S1079979613002088"],"URL":"https:\/\/doi.org\/10.1016\/j.bcmd.2013.09.004","relation":{"erratum":[{"id-type":"doi","id":"10.1016\/j.bcmd.2014.02.001","asserted-by":"object"}]},"ISSN":["1079-9796"],"issn-type":[{"value":"1079-9796","type":"print"}],"subject":[],"published":{"date-parts":[[2014,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Interleukin-6 directly impairs the erythroid development of human TF-1 erythroleukemic cells","name":"articletitle","label":"Article Title"},{"value":"Blood Cells, Molecules, and Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bcmd.2013.09.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}