{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T15:13:25Z","timestamp":1767280405470,"version":"build-2065373602"},"reference-count":11,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2014,9,1]],"date-time":"2014-09-01T00:00:00Z","timestamp":1409529600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,9,1]],"date-time":"2014-09-01T00:00:00Z","timestamp":1409529600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Blood Cells, Molecules, and Diseases"],"published-print":{"date-parts":[[2014,9]]},"DOI":"10.1016\/j.bcmd.2014.05.002","type":"journal-article","created":{"date-parts":[[2014,5,28]],"date-time":"2014-05-28T10:34:33Z","timestamp":1401273273000},"page":"133-137","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Molecular diagnostics of the HBB gene in an Omani cohort using bench-top DNA Ion Torrent PGM technology"],"prefix":"10.1016","volume":"53","author":[{"given":"S.M.","family":"Hassan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.H.A.M.","family":"Vossen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Chessa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.T.","family":"den Dunnen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Bakker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.C.","family":"Giordano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.L.","family":"Harteveld","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bcmd.2014.05.002_bb0005","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1038\/nrg2626","article-title":"Sequencing technologies\u2014the next generation","volume":"11","author":"Metzker","year":"2010","journal-title":"Nat. Rev. Genet."},{"key":"10.1016\/j.bcmd.2014.05.002_bb0010","doi-asserted-by":"crossref","first-page":"6466","DOI":"10.1073\/pnas.0601184103","article-title":"Direct electrical detection of DNA synthesis","volume":"103","author":"Pourmand","year":"2006","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.bcmd.2014.05.002_bb0015","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1038\/nature10242","article-title":"An integrated semiconductor device enabling non-optical genome sequencing","volume":"475","author":"Rothberg","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.bcmd.2014.05.002_bb0020","doi-asserted-by":"crossref","first-page":"24","DOI":"10.7171\/jbt.12-2301-003","article-title":"Rapid detection of the ACMG\/ACOG-recommended 23 CFTR disease-causing mutations using Ion Torrent semiconductor sequencing","volume":"23","author":"Elliott","year":"2012","journal-title":"J. Biomol. Tech."},{"key":"10.1016\/j.bcmd.2014.05.002_bb0025","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1007\/978-1-61779-516-9_19","article-title":"Generating barcoded libraries for multiplex high-throughput sequencing","volume":"840","author":"Knapp","year":"2012","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.bcmd.2014.05.002_bb0030","doi-asserted-by":"crossref","first-page":"9387","DOI":"10.1073\/pnas.0702165104","article-title":"Multigene amplification and massively parallel sequencing for cancer mutation discovery","volume":"104","author":"Dahl","year":"2007","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.bcmd.2014.05.002_bb0035","first-page":"365","article-title":"Primer3 on the WWW for general users and for biologist programmers","volume":"132","author":"Rozen","year":"2000","journal-title":"Methods Mol. Biol."},{"issue":"5","key":"10.1016\/j.bcmd.2014.05.002_bb0040","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1038\/nbt.2198","article-title":"Performance comparison of benchtop high-throughput sequencing platforms","volume":"30","author":"Loman","year":"2012","journal-title":"Nat. Biotechnol."},{"issue":"11","key":"10.1016\/j.bcmd.2014.05.002_bb0045","doi-asserted-by":"crossref","first-page":"3073","DOI":"10.1002\/eji.201242517","article-title":"Next generation sequencing for TCR repertoire profiling: platform-specific features and correction algorithms","volume":"42","author":"Bolotin","year":"2012","journal-title":"Eur. J. Immunol."},{"issue":"9","key":"10.1016\/j.bcmd.2014.05.002_bb0050","doi-asserted-by":"crossref","first-page":"2526","DOI":"10.1111\/j.1462-2920.2012.02791.x","article-title":"Towards quantitative metagenomics of wild viruses and other ultra-low concentration DNA samples: a rigorous assessment and optimization of the linker amplification method. Society for Applied Microbiology and Blackwell Publishing","volume":"14","author":"Duhaime","year":"2012","journal-title":"Environ. Microbiol."},{"issue":"2","key":"10.1016\/j.bcmd.2014.05.002_bb0055","doi-asserted-by":"crossref","first-page":"127","DOI":"10.3109\/03630261003673147","article-title":"Extended molecular spectrum of beta- and alpha-thalassemia in Oman","volume":"34","author":"Hassan","year":"2010","journal-title":"Hemoglobin"}],"container-title":["Blood Cells, Molecules, and Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1079979614000527?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1079979614000527?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T12:30:15Z","timestamp":1761049815000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1079979614000527"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,9]]},"references-count":11,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2014,9]]}},"alternative-id":["S1079979614000527"],"URL":"https:\/\/doi.org\/10.1016\/j.bcmd.2014.05.002","relation":{},"ISSN":["1079-9796"],"issn-type":[{"type":"print","value":"1079-9796"}],"subject":[],"published":{"date-parts":[[2014,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Molecular diagnostics of the HBB gene in an Omani cohort using bench-top DNA Ion Torrent PGM technology","name":"articletitle","label":"Article Title"},{"value":"Blood Cells, Molecules, and Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bcmd.2014.05.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}