{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T13:51:18Z","timestamp":1771509078974,"version":"3.50.1"},"reference-count":39,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,7,1]],"date-time":"2019-07-01T00:00:00Z","timestamp":1561939200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,7,1]],"date-time":"2019-07-01T00:00:00Z","timestamp":1561939200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Blood Cells, Molecules, and Diseases"],"published-print":{"date-parts":[[2019,7]]},"DOI":"10.1016\/j.bcmd.2019.04.002","type":"journal-article","created":{"date-parts":[[2019,4,7]],"date-time":"2019-04-07T01:05:00Z","timestamp":1554599100000},"page":"72-75","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Pagophagia in men with iron-deficiency anemia"],"prefix":"10.1016","volume":"77","author":[{"given":"James C.","family":"Barton","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. Clayborn","family":"Barton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luigi F.","family":"Bertoli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bcmd.2019.04.002_bb0005","first-page":"9","article-title":"Pica associated with iron deficiency or depletion: clinical and laboratory correlates in 262 non-pregnant adult outpatients","volume":"10","author":"Barton","year":"2010","journal-title":"BMC Blood Disord"},{"key":"10.1016\/j.bcmd.2019.04.002_bb0010","doi-asserted-by":"crossref","first-page":"435","DOI":"10.7326\/0003-4819-69-3-435","article-title":"Pagophagia and iron deficiency anemia","volume":"69","author":"Reynolds","year":"1968","journal-title":"Ann. Intern. Med."},{"key":"10.1016\/j.bcmd.2019.04.002_bb0015","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1001\/jama.1969.03150160025005","article-title":"Pagophagia and iron lack","volume":"207","author":"Coltman","year":"1969","journal-title":"JAMA"},{"key":"10.1016\/j.bcmd.2019.04.002_bb0020","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1017\/S0033291700038022","article-title":"Pagophagia, or compulsive ice consumption: a historical perspective","volume":"22","author":"Parry-Jones","year":"1992","journal-title":"Psychol. Med."},{"key":"10.1016\/j.bcmd.2019.04.002_bb0025","first-page":"321","article-title":"Rapid regression of prolonged pagophagia after treatment of iron deficiency","volume":"30","author":"Sontag","year":"2001","journal-title":"Presse Med."},{"key":"10.1016\/j.bcmd.2019.04.002_bb0030","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1002\/2327-6924.12268","article-title":"Ask about ice, then consider iron","volume":"28","author":"Rabel","year":"2016","journal-title":"J. Am. Assoc. Nurse Pract."},{"key":"10.1016\/j.bcmd.2019.04.002_bb0035","unstructured":"L. Riverius, Praxis Medica (1640 (Paris: Olivarii de Varennes)) translated by N. Culpeper, A. Cole, and A. Rowland as: The Practice of Physick, in Seventeen Several Books. Wherein Is Plainly Set Forth the Nature, Cause, Differences, and Several Sorts of Signs: Together With the Cure of all Diseases in the Body of Man. 1658 (London: P. Cole)."},{"key":"10.1016\/j.bcmd.2019.04.002_bb0040","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.bcmd.2011.12.003","article-title":"Common TMPRSS6 mutations and iron, erythrocyte, and pica phenotypes in 48 women with iron deficiency or depletion","volume":"48","author":"Lee","year":"2012","journal-title":"Blood Cells Mol. Dis."},{"key":"10.1016\/j.bcmd.2019.04.002_bb0045","first-page":"1069","article-title":"Pica and food craving in adult patients with iron deficiency in Bloemfontein, South Africa","volume":"97","author":"Louw","year":"2007","journal-title":"S Afr Med J."},{"key":"10.1016\/j.bcmd.2019.04.002_bb0050","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1016\/S0025-6196(11)60774-X","article-title":"Nocturnal pagophagia complicating gastric bypass","volume":"83","author":"Marinella","year":"2008","journal-title":"Mayo Clin. Proc."},{"key":"10.1016\/j.bcmd.2019.04.002_bb0055","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1186\/1752-1947-4-86","article-title":"Pica in iron deficiency: a case series","volume":"4","author":"Khan","year":"2010","journal-title":"J. Med. Case Rep."},{"key":"10.1016\/j.bcmd.2019.04.002_bb0060","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1111\/j.1365-2141.1976.tb00204.x","article-title":"Pica: a compulsion caused by iron deficiency","volume":"34","author":"Crosby","year":"1976","journal-title":"Br. J. Haematol."},{"key":"10.1016\/j.bcmd.2019.04.002_bb0065","doi-asserted-by":"crossref","first-page":"1334","DOI":"10.1126\/science.169.3952.1334","article-title":"Pagophagia in the albino rat","volume":"169","author":"Woods","year":"1970","journal-title":"Science"},{"key":"10.1016\/j.bcmd.2019.04.002_bb0070","series-title":"Wintrobe's Clinical Hematology","first-page":"617","article-title":"Iron deficiency and related disorders","author":"Goodnough","year":"2014"},{"key":"10.1016\/j.bcmd.2019.04.002_bb0075","doi-asserted-by":"crossref","first-page":"150","DOI":"10.3109\/01443615.2011.638093","article-title":"Characteristics of pica practice during pregnancy in a sample of Argentine women","volume":"32","author":"Lopez","year":"2012","journal-title":"J. Obstet. Gynaecol."},{"key":"10.1016\/j.bcmd.2019.04.002_bb0080","first-page":"244","article-title":"Pagophagia and iron lack","volume":"27","author":"Coltman","year":"1969","journal-title":"Nutr. Rev."},{"key":"10.1016\/j.bcmd.2019.04.002_bb0085","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1080\/08880010590896486","article-title":"Craving for ice and iron-deficiency anemia: a case series from Oman","volume":"22","author":"Osman","year":"2005","journal-title":"Pediatr. Hematol. Oncol."},{"key":"10.1016\/j.bcmd.2019.04.002_bb0090","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.appet.2017.08.033","article-title":"Pica is prevalent and strongly associated with iron deficiency among Hispanic pregnant women living in the United States","volume":"120","author":"Roy","year":"2018","journal-title":"Appetite"},{"key":"10.1016\/j.bcmd.2019.04.002_bb0095","doi-asserted-by":"crossref","first-page":"1637","DOI":"10.1111\/trf.12061","article-title":"Ascertainment of iron deficiency and depletion in blood donors through screening questions for pica and restless legs syndrome","volume":"53","author":"Bryant","year":"2013","journal-title":"Transfusion"},{"key":"10.1016\/j.bcmd.2019.04.002_bb0100","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1007\/BF02599550","article-title":"Pica: its frequency and significance in patients with iron-deficiency anemia due to chronic gastrointestinal blood loss","volume":"4","author":"Rector","year":"1989","journal-title":"J. Gen. Intern. Med."},{"key":"10.1016\/j.bcmd.2019.04.002_bb0105","doi-asserted-by":"crossref","first-page":"2191","DOI":"10.1001\/jama.2013.281053","article-title":"Ethical principles for medical research involving human subjects","volume":"310","author":"World Medical Association Declaration of Helsinki","year":"2013","journal-title":"JAMA"},{"key":"10.1016\/j.bcmd.2019.04.002_bb0110","series-title":"Haemoglobin concentrations for the diagnosis of anaemia and assessment of severity. Vitamin and Mineral Nutrition Information System","first-page":"1","author":"WHO","year":"2011"},{"key":"10.1016\/j.bcmd.2019.04.002_bb0115","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1111\/j.1365-2133.1969.tb15958.x","article-title":"Iron deficiency and the oral mucous membrane","volume":"81","author":"Jacobs","year":"1969","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.bcmd.2019.04.002_bb0120","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.1016\/S0140-6736(61)90903-5","article-title":"Iron-containing enzymes in the buccal epithelium","volume":"2","author":"Jacobs","year":"1961","journal-title":"Lancet"},{"key":"10.1016\/j.bcmd.2019.04.002_bb0125","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.amjmed.2004.07.050","article-title":"Pica and food craving in patients with iron-deficiency anemia: a case-control study in France","volume":"118","author":"Kettaneh","year":"2005","journal-title":"Am. J. Med."},{"key":"10.1016\/j.bcmd.2019.04.002_bb0130","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/j.mehy.2014.07.016","article-title":"Pagophagia improves neuropsychological processing speed in iron-deficiency anemia","volume":"83","author":"Hunt","year":"2014","journal-title":"Med. Hypotheses"},{"key":"10.1016\/j.bcmd.2019.04.002_bb0135","doi-asserted-by":"crossref","first-page":"1691","DOI":"10.1056\/NEJM199312023292303","article-title":"Evaluation of the gastrointestinal tract in patients with iron-deficiency anemia","volume":"329","author":"Rockey","year":"1993","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.bcmd.2019.04.002_bb0140","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/S0002-9343(97)00168-X","article-title":"Prospective evaluation of the gastrointestinal tract in patients with iron deficiency and no systemic or gastrointestinal symptoms or signs","volume":"103","author":"Wilcox","year":"1997","journal-title":"Am. J. Med."},{"key":"10.1016\/j.bcmd.2019.04.002_bb0145","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1097\/00005792-198211000-00004","article-title":"Non-hematologic effects of chronic iron deficiency. A study of patients with polycythemia vera treated solely with venesections","volume":"61","author":"Rector","year":"1982","journal-title":"Medicine (Baltimore)"},{"key":"10.1016\/j.bcmd.2019.04.002_bb0150","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1038\/ng.456","article-title":"Common variants in TMPRSS6 are associated with iron status and erythrocyte volume","volume":"41","author":"Benyamin","year":"2009","journal-title":"Nat. Genet."},{"key":"10.1016\/j.bcmd.2019.04.002_bb0155","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.1038\/ng.462","article-title":"Genome-wide association study identifies variants in TMPRSS6 associated with hemoglobin levels","volume":"41","author":"Chambers","year":"2009","journal-title":"Nat. Genet."},{"key":"10.1016\/j.bcmd.2019.04.002_bb0160","series-title":"Iron in drinking-water. Background Document for Development of WHO Guidelines for Drinking-Water Quality","first-page":"1","author":"WHO","year":"2003"},{"key":"10.1016\/j.bcmd.2019.04.002_bb0165","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1007\/s12185-009-0360-z","article-title":"The association of pagophagia with Helicobacter pylori infection in patients with iron-deficiency anemia","volume":"90","author":"Asma","year":"2009","journal-title":"Int. J. Hematol."},{"key":"10.1016\/j.bcmd.2019.04.002_bb0170","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1080\/09537100903137306","article-title":"Platelet counts in adults with iron deficiency anemia","volume":"20","author":"Kuku","year":"2009","journal-title":"Platelets"},{"key":"10.1016\/j.bcmd.2019.04.002_bb0175","first-page":"398","article-title":"Platelet parameters in women with iron deficiency anemia","volume":"98","author":"Kadikoylu","year":"2006","journal-title":"J. Natl. Med. Assoc."},{"key":"10.1016\/j.bcmd.2019.04.002_bb0180","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.annepidem.2005.06.052","article-title":"Platelet counts differ by sex, ethnicity, and age in the United States","volume":"16","author":"Segal","year":"2006","journal-title":"Ann. Epidemiol."},{"key":"10.1016\/j.bcmd.2019.04.002_bb0185","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/S0022-2143(00)70026-6","article-title":"Peripheral blood erythrocyte parameters in hemochromatosis: evidence for increased erythrocyte hemoglobin content","volume":"135","author":"Barton","year":"2000","journal-title":"J. Lab. Clin. Med."},{"key":"10.1016\/j.bcmd.2019.04.002_bb0190","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1046\/j.1365-2141.2003.04215.x","article-title":"Haematological effects of the C282Y HFE mutation in homozygous and heterozygous states among subjects of northern and southern European ancestry","volume":"120","author":"Beutler","year":"2003","journal-title":"Br. J. Haematol."},{"key":"10.1016\/j.bcmd.2019.04.002_bb0195","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1006\/bcmd.1999.0267","article-title":"The effect of transferrin polymorphisms on iron metabolism","volume":"25","author":"Lee","year":"1999","journal-title":"Blood Cells Mol. Dis."}],"container-title":["Blood Cells, Molecules, and Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1079979619301305?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1079979619301305?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T12:34:41Z","timestamp":1761050081000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1079979619301305"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7]]},"references-count":39,"alternative-id":["S1079979619301305"],"URL":"https:\/\/doi.org\/10.1016\/j.bcmd.2019.04.002","relation":{},"ISSN":["1079-9796"],"issn-type":[{"value":"1079-9796","type":"print"}],"subject":[],"published":{"date-parts":[[2019,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Pagophagia in men with iron-deficiency anemia","name":"articletitle","label":"Article Title"},{"value":"Blood Cells, Molecules, and Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bcmd.2019.04.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}