{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T00:42:49Z","timestamp":1761093769920,"version":"build-2065373602"},"reference-count":19,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,6,16]],"date-time":"2023-06-16T00:00:00Z","timestamp":1686873600000},"content-version":"am","delay-in-days":227,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Blood Cells, Molecules, and Diseases"],"published-print":{"date-parts":[[2022,11]]},"DOI":"10.1016\/j.bcmd.2022.102688","type":"journal-article","created":{"date-parts":[[2022,6,11]],"date-time":"2022-06-11T19:21:09Z","timestamp":1654975269000},"page":"102688","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Liver kinase B1 (LKB1) in murine erythroid progenitors modulates erythropoietin setpoint in association with maturation control"],"prefix":"10.1016","volume":"97","author":[{"suffix":"III","given":"Zollie","family":"White","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kamaleldin E.","family":"Elagib","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alejandro A.","family":"Gru","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adam N.","family":"Goldfarb","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bcmd.2022.102688_bb0005","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.01913","article-title":"A critical role for mTORC1 in erythropoiesis and anemia","volume":"3","author":"Knight","year":"2014","journal-title":"elife"},{"issue":"8","key":"10.1016\/j.bcmd.2022.102688_bb0010","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1038\/nrc2676","article-title":"The LKB1\u2013AMPK pathway: metabolism and growth control in tumour suppression","volume":"9","author":"Shackelford","year":"2009","journal-title":"Nat. Rev. Cancer"},{"issue":"7324","key":"10.1016\/j.bcmd.2022.102688_bb0015","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1038\/nature09571","article-title":"Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells","volume":"468","author":"Nakada","year":"2010","journal-title":"Nat"},{"issue":"7324","key":"10.1016\/j.bcmd.2022.102688_bb0020","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1038\/nature09595","article-title":"Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells","volume":"468","author":"Gan","year":"2010","journal-title":"Nature"},{"issue":"7324","key":"10.1016\/j.bcmd.2022.102688_bb0025","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1038\/nature09572","article-title":"The Lkb1 metabolic sensor maintains haematopoietic stem cell survival","volume":"468","author":"Gurumurthy","year":"2010","journal-title":"Nature"},{"issue":"1","key":"10.1016\/j.bcmd.2022.102688_bb0030","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41467-021-21938-2","article-title":"Iron control of erythroid microtubule cytoskeleton as a potential target in treatment of iron-restricted anemia","volume":"12","author":"Goldfarb","year":"2021","journal-title":"Nat. Commun."},{"issue":"2","key":"10.1016\/j.bcmd.2022.102688_bb0035","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1002\/(SICI)1526-968X(200002)26:2<99::AID-GENE1>3.0.CO;2-B","article-title":"Cre recombinase: the universal reagent for genome tailoring","volume":"26","author":"Nagy","year":"2000","journal-title":"Genesis"},{"issue":"3","key":"10.1016\/j.bcmd.2022.102688_bb0040","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1182\/blood-2003-05-1442","article-title":"A mouse model for visualization and conditional mutations in the erythroid lineage","volume":"104","author":"Heinrich","year":"2004","journal-title":"Blood"},{"issue":"20","key":"10.1016\/j.bcmd.2022.102688_bb0045","doi-asserted-by":"crossref","first-page":"2646","DOI":"10.1182\/bloodadvances.2018023515","article-title":"Absolute proteome quantification of highly purified populations of circulating reticulocytes and mature erythrocytes","volume":"2","author":"Gautier","year":"2018","journal-title":"Blood Adv."},{"key":"10.1016\/j.bcmd.2022.102688_bb0050","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.exphem.2016.09.006","article-title":"The AMP-activated protein kinase beta 1 subunit modulates erythrocyte integrity","volume":"45","author":"Cambridge","year":"2017","journal-title":"Exp. Hematol."},{"issue":"4","key":"10.1016\/j.bcmd.2022.102688_bb0055","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1096\/fj.08-121772","article-title":"Regulation of erythrocyte survival by AMP-activated protein kinase","volume":"23","author":"F\u00f6ller","year":"2009","journal-title":"FASEB J."},{"issue":"26","key":"10.1016\/j.bcmd.2022.102688_bb0060","doi-asserted-by":"crossref","first-page":"19976","DOI":"10.1074\/jbc.M110.102467","article-title":"AMPKalpha1 deletion shortens erythrocyte life span in mice: role of oxidative stress","volume":"285","author":"Wang","year":"2010","journal-title":"J. Biol. Chem."},{"issue":"16","key":"10.1016\/j.bcmd.2022.102688_bb0065","doi-asserted-by":"crossref","first-page":"3667","DOI":"10.1016\/j.febslet.2010.07.041","article-title":"Maintenance of red blood cell integrity by AMP-activated protein kinase \u03b11 catalytic subunit","volume":"584","author":"Foretz","year":"2010","journal-title":"FEBS Lett."},{"issue":"1","key":"10.1016\/j.bcmd.2022.102688_bb0070","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1096\/fj.10-169383","article-title":"The AMPKyl subunit plays an essential role in erythrocyte membrane elasticity, and its genetic inactivation induces splenomegaly and anemia","volume":"25","author":"Foretz","year":"2011","journal-title":"FASEB J."},{"issue":"2","key":"10.1016\/j.bcmd.2022.102688_bb0075","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1084\/jem.20170396","article-title":"Iron modulation of erythropoiesis is associated with scribble-mediated control of the erythropoietin receptor","volume":"215","author":"Khalil","year":"2017","journal-title":"J. Exp. Med."},{"issue":"4","key":"10.1016\/j.bcmd.2022.102688_bb0080","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1038\/sj.emboj.7600110","article-title":"LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK\/PAR-1","volume":"23","author":"Lizcano","year":"2004","journal-title":"EMBO J."},{"issue":"23","key":"10.1016\/j.bcmd.2022.102688_bb0085","doi-asserted-by":"crossref","first-page":"8874","DOI":"10.1074\/jbc.RA118.003547","article-title":"AMP-activated protein kinase selectively inhibited by the type II inhibitor SBI-0206965","volume":"293","author":"Dite","year":"2018","journal-title":"J. Biol. Chem."},{"issue":"5","key":"10.1016\/j.bcmd.2022.102688_bb0090","doi-asserted-by":"crossref","first-page":"907","DOI":"10.3324\/haematol.2018.191403","article-title":"Finely-tuned regulation of AMP-activated protein kinase is crucial for human adult erythropoiesis","volume":"104","author":"Ladli","year":"2019","journal-title":"Haematologica"},{"issue":"1","key":"10.1016\/j.bcmd.2022.102688_bb0095","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41467-021-27562-4","article-title":"EpoR stimulates rapid cycling and larger red cells during mouse and human erythropoiesis","volume":"12","author":"Hidalgo","year":"2021","journal-title":"Nat. Commun."}],"container-title":["Blood Cells, Molecules, and Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1079979622000456?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1079979622000456?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T12:36:17Z","timestamp":1761050177000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1079979622000456"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11]]},"references-count":19,"alternative-id":["S1079979622000456"],"URL":"https:\/\/doi.org\/10.1016\/j.bcmd.2022.102688","relation":{},"ISSN":["1079-9796"],"issn-type":[{"type":"print","value":"1079-9796"}],"subject":[],"published":{"date-parts":[[2022,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Liver kinase B1 (LKB1) in murine erythroid progenitors modulates erythropoietin setpoint in association with maturation control","name":"articletitle","label":"Article Title"},{"value":"Blood Cells, Molecules, and Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bcmd.2022.102688","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"102688"}}