{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T06:16:17Z","timestamp":1792044977502,"version":"4.4.0"},"reference-count":225,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,3,1]],"date-time":"2018-03-01T00:00:00Z","timestamp":1519862400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01GM107846"],"award-info":[{"award-number":["R01GM107846"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01GMCA175803"],"award-info":[{"award-number":["R01GMCA175803"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004917","name":"Cancer Prevention Research Institute of Texas","doi-asserted-by":"publisher","award":["DP150074"],"award-info":[{"award-number":["DP150074"]}],"id":[{"id":"10.13039\/100004917","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical Pharmacology"],"published-print":{"date-parts":[[2018,3]]},"DOI":"10.1016\/j.bcp.2017.09.010","type":"journal-article","created":{"date-parts":[[2017,9,23]],"date-time":"2017-09-23T08:50:05Z","timestamp":1506156605000},"page":"5-19","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":262,"special_numbering":"C","title":["A timeline of hydrogen sulfide (H2S) research: From environmental toxin to biological mediator"],"prefix":"10.1016","volume":"149","author":[{"given":"Csaba","family":"Szabo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bcp.2017.09.010_b0005","unstructured":"Ramazzini B. De Morbis Artificum Diatriba. Mutinae (Modena). Antonii Capponi, 1700."},{"key":"10.1016\/j.bcp.2017.09.010_b0010","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1093\/occmed\/47.3.167","article-title":"JS. The heritage of Bernardino Ramazzini","volume":"47","author":"Felton","year":"1997","journal-title":"Occup Med"},{"key":"10.1016\/j.bcp.2017.09.010_b0015","series-title":"The Latin text of 1713, rev. with translation and notes by W. C. Wright","first-page":"151","author":"De Morbis Anificum Diatriba","year":"1940"},{"key":"10.1016\/j.bcp.2017.09.010_b0020","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1016\/0005-2728(81)90170-5","article-title":"Oxidation of sulphide by cytochrome aa3","volume":"637","author":"Nicholls","year":"1981","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bcp.2017.09.010_b0025","doi-asserted-by":"crossref","first-page":"3492","DOI":"10.1073\/pnas.1111297109","article-title":"Crucial role of copper in detection of metal-coordinating odorants","volume":"109","author":"Duan","year":"2012","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bcp.2017.09.010_b0030","first-page":"187","article-title":"Rapport sur une esp\u00e9ce de mephitisme des fosses d'aisance, produite par le gas azote","volume":"IX","author":"Dupuyturen","year":"1806","journal-title":"J. Med."},{"key":"10.1016\/j.bcp.2017.09.010_b0035","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2307\/4577000","article-title":"Hydrogen sulphide literature","volume":"39","author":"Mitchell","year":"1924","journal-title":"Public Health Rep."},{"key":"10.1016\/j.bcp.2017.09.010_b0040","first-page":"19","article-title":"Pr\u00e9cis d'experiences faites sur les animaux avec le gaz hydrog\u00e9ne sulfur\u00e9","volume":"15","author":"Chaussier","year":"1908","journal-title":"J. Gen. de Med., Chir. et Pharm. Paris"},{"key":"10.1016\/j.bcp.2017.09.010_b0045","doi-asserted-by":"crossref","first-page":"25","DOI":"10.3109\/10408448409029321","article-title":"A critical review of the literature on hydrogen sulfide toxicity","volume":"13","author":"Beauchamp","year":"1984","journal-title":"CRC Crit. Rev. Toxicol."},{"key":"10.1016\/j.bcp.2017.09.010_b0050","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1146\/annurev.pa.32.040192.000545","article-title":"Toxicology of hydrogen sulfide","volume":"32","author":"Reiffenstein","year":"1992","journal-title":"Ann. Rev. Pharmacol. Toxicol."},{"key":"10.1016\/j.bcp.2017.09.010_b0055","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1002\/(SICI)1097-0274(199902)35:2<192::AID-AJIM11>3.0.CO;2-C","article-title":"Hydrogen sulfide poisoning: clarification of some controversial issues","volume":"35","author":"Milby","year":"1999","journal-title":"Am. J. Ind. Med."},{"key":"10.1016\/j.bcp.2017.09.010_b0060","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1097\/01.paf.0000163834.87968.08","article-title":"Death by sewer gas: case report of a double fatality and review of the literature","volume":"26","author":"Knight","year":"2005","journal-title":"Am. J. Forensic Med. Pathol."},{"key":"10.1016\/j.bcp.2017.09.010_b0065","unstructured":"Toxicological Review of Hydrogen Sulfide. (CAS No. 7783-06-4) In Support of Summary Information on the Integrated Risk Information System (IRIS). U.S. Environmental Protection Agency Washington, DC. June 2003."},{"key":"10.1016\/j.bcp.2017.09.010_b0070","series-title":"Handbook of Clinical Neurology","doi-asserted-by":"crossref","DOI":"10.1016\/B978-0-444-62627-1.00008-1","article-title":"Hydrogen sulfide intoxication","author":"Guidotti","year":"2015"},{"key":"10.1016\/j.bcp.2017.09.010_b0075","unstructured":"Toxicological Profile for Hydrogen Sulfide and Carbonyl Sulfide. US Department of Health and Human Services Public Health Service - Agency for Toxic Substances and Disease Registry. November 2016."},{"key":"10.1016\/j.bcp.2017.09.010_b0080","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1158\/1541-7786.MCR-05-0126","article-title":"Evidence that hydrogen sulfide is a genotoxic agent","volume":"4","author":"Attene-Ramos","year":"2006","journal-title":"Mol. Cancer Res."},{"key":"10.1016\/j.bcp.2017.09.010_b0085","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1080\/009841098158773","article-title":"Inhibition of respiratory and bioenergetic mechanisms by hydrogen sulfide in mammalian brain","volume":"54","author":"Nicholson","year":"1998","journal-title":"J. Toxicol. Environ. Health"},{"key":"10.1016\/j.bcp.2017.09.010_b0090","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1016\/0041-008X(90)90321-K","article-title":"Effects of hydrogen sulfide exposure on lung mitochondrial respiratory chain enzymes in rats","volume":"103","author":"Khan","year":"1990","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.bcp.2017.09.010_b0095","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1093\/toxsci\/65.1.18","article-title":"Cytochrome oxidase inhibition induced by acute hydrogen sulfide inhalation: correlation with tissue sulfide concentrations in the rat brain, liver, lung, and nasal epithelium","volume":"65","author":"Dorman","year":"2002","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.bcp.2017.09.010_b0100","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.taap.2004.03.010","article-title":"Respiratory tract toxicity of inhaled hydrogen sulfide in Fischer-344 rats, Sprague-Dawley rats, and B6C3F1 mice following subchronic (90-day) exposure","volume":"198","author":"Dorman","year":"2004","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.bcp.2017.09.010_b0105","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1177\/0192623308317422","article-title":"Gene expression changes following acute hydrogen sulfide (H2S)-induced nasal respiratory epithelial injury","volume":"36","author":"Roberts","year":"2008","journal-title":"Toxicol. Pathol."},{"key":"10.1016\/j.bcp.2017.09.010_b0110","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/0304-3894(86)85008-7","article-title":"A new look at physiologic respiratory response to hydrogen sulfide poisoning","volume":"13","author":"Ammann","year":"1986","journal-title":"J. Hazardous Mater."},{"key":"10.1016\/j.bcp.2017.09.010_b0115","unstructured":"Kaufmann S, Rosenthal J. \u00dcber die Wirkungen der Schwefelwasserstoffs auf den Tierischen Organismus. Arch. f. Anat. Physiol. u. Wissensch. Med. Leipz. 1895;659\u2013675."},{"key":"10.1016\/j.bcp.2017.09.010_b0120","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1085\/jgp.24.5.597","article-title":"Studies on cell metabolism and cell division: V. Cytochrome oxidase activity in the eggs of Arbacia Punctulata","volume":"24","author":"Krahl","year":"1941","journal-title":"Gen. Physiol."},{"key":"10.1016\/j.bcp.2017.09.010_b0125","doi-asserted-by":"crossref","first-page":"4567","DOI":"10.1016\/S0021-9258(18)99687-0","article-title":"Schoener B High and low energy states of cytochromes I. In mitochondria","volume":"241","author":"Chance","year":"1965","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bcp.2017.09.010_b0130","first-page":"24","article-title":"The effect of sulphide on cytochrome aa3. Isoteric and allosteric shifts of the reduced a-peak","volume":"396","author":"Nicholls","year":"1975","journal-title":"Biochm. Biophys. Acta"},{"key":"10.1016\/j.bcp.2017.09.010_b0135","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1042\/BST20130070","article-title":"Sulfide inhibition of and metabolism by cytochrome c oxidase","volume":"41","author":"Nicholls","year":"2013","journal-title":"Biochem. Soc. Trans."},{"key":"10.1016\/j.bcp.2017.09.010_b0140","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1126\/science.1108581","article-title":"H2S induces a suspended animation-like state in mice","volume":"308","author":"Blackstone","year":"2005","journal-title":"Science"},{"key":"10.1016\/j.bcp.2017.09.010_b0145","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1097\/ALN.0b013e318167af0d","article-title":"Inhaled hydrogen sulfide: a rapidly reversible inhibitor of cardiac and metabolic function in the mouse","volume":"108","author":"Volpato","year":"2008","journal-title":"Anesthesiology"},{"key":"10.1016\/j.bcp.2017.09.010_b0150","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1097\/SHK.0b013e31823f19a0","article-title":"Inhaled hydrogen sulfide induces suspended animation, but does not alter the inflammatory response after blunt chest trauma","volume":"37","author":"Seitz","year":"2012","journal-title":"Shock"},{"key":"10.1016\/j.bcp.2017.09.010_b0155","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1124\/jpet.111.187237","article-title":"Is hydrogen sulfide-induced suspended animation general anesthesia?","volume":"341","author":"Li","year":"2012","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.bcp.2017.09.010_b0160","unstructured":"Gayon MU. Note presentee par M. Pasteur. Sur les alterations des oeufs, a l'occasion d'une Note de MM. A. Bechamp et G.Eustache. Ann Ecole Normale Super S\u00e9r.2. 1877;IV:205."},{"key":"10.1016\/j.bcp.2017.09.010_b0165","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1002\/jsfa.2740240103","article-title":"Hydrogen sulphide production in eggs and egg products as a result of heating","volume":"24","author":"Germs","year":"1973","journal-title":"J. Sci Food Agric."},{"key":"10.1016\/j.bcp.2017.09.010_b0170","doi-asserted-by":"crossref","first-page":"21972","DOI":"10.1073\/pnas.0908047106","article-title":"Hydrogen sulfide is an endogenous stimulator of angiogenesis","volume":"106","author":"Papapetropoulos","year":"2009","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bcp.2017.09.010_b0175","first-page":"104","article-title":"\u00dcber Spirillum Desulfuricans als Ursache von Sulfatreduction","volume":"21","author":"Beijerinck","year":"1895","journal-title":"Zentralbl. Bakteriol. Parasitenk. Infektionskr. Hyg Abt Orig"},{"key":"10.1016\/j.bcp.2017.09.010_b0180","first-page":"833","article-title":"Beitrag zur hygieneschen Beurteilung des Trinkwassers","volume":"16","author":"Schardinger","year":"1984","journal-title":"Zentralbl Bakteriol Parasitenk Infektionskr Hyg Abt Orig"},{"key":"10.1016\/j.bcp.2017.09.010_b0185","doi-asserted-by":"crossref","DOI":"10.1136\/bmj.1.1952.1387","article-title":"A simple method for demonstrating the production of gas by bacteria","author":"Durham","year":"1898","journal-title":"Brit. Med. J."},{"key":"10.1016\/j.bcp.2017.09.010_b0190","unstructured":"M.A. Orlowski, Hydrogene sulfure comme produit des certaines bacteries. J med milit Russe, cited in: Jber Fortschr path Microorg 1897;11:528."},{"key":"10.1016\/j.bcp.2017.09.010_b0195","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1128\/JB.5.3.231-252.1920","article-title":"The production of hydrogen sulphide by bacteria","volume":"5","author":"Myers","year":"1920","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.bcp.2017.09.010_b0200","first-page":"117","article-title":"Ability to form H2S in various bacteria","volume":"206","author":"Rodler","year":"1968","journal-title":"Zentralbl Bakteriol Orig"},{"key":"10.1016\/j.bcp.2017.09.010_b0205","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1099\/00221287-8-3-397","article-title":"Hydrogen sulphide production by bacteria","volume":"8","author":"Clarke","year":"1953","journal-title":"J. Gen. Microbiol."},{"key":"10.1016\/j.bcp.2017.09.010_b0210","first-page":"424","article-title":"Production of H2S in Brucella","volume":"15","author":"Massidda","year":"1964","journal-title":"Nuovi. Ann. Ig Microbiol."},{"key":"10.1016\/j.bcp.2017.09.010_b0215","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1128\/AEM.13.4.570-574.1965","article-title":"Sensitivity of mixed populations of Staphylococcus aureus and Eschericia coli to mercurials","volume":"13","author":"Stutzenberger","year":"1965","journal-title":"Appl. Microbiol."},{"key":"10.1016\/j.bcp.2017.09.010_b0220","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1146\/annurev.mi.26.100172.001015","article-title":"Production of volatile sulfur compounds by microorganisms","volume":"26","author":"Kadota","year":"1972","journal-title":"Ann. Rev. Microbiol."},{"key":"10.1016\/j.bcp.2017.09.010_b0225","doi-asserted-by":"crossref","first-page":"28166","DOI":"10.3402\/jom.v7.28166","article-title":"Estimation of bacterial hydrogen sulfide production in vitro","volume":"7","author":"Basic","year":"2015","journal-title":"J. Oral Microbiol."},{"key":"10.1016\/j.bcp.2017.09.010_b0230","doi-asserted-by":"crossref","first-page":"2389","DOI":"10.1128\/IAI.00121-16","article-title":"Control of Clostridium difficile physiopathology in response to cysteine availability","volume":"84","author":"Dubois","year":"2016","journal-title":"Infect. Immun."},{"key":"10.1016\/j.bcp.2017.09.010_b0235","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1099\/00221287-14-2-315","article-title":"The production of hydrogen sulphide from thiosulphate by Escherichia coli","volume":"14","author":"Artman","year":"1956","journal-title":"J. Gen. Microbiol."},{"key":"10.1016\/j.bcp.2017.09.010_b0240","doi-asserted-by":"crossref","first-page":"5762","DOI":"10.1128\/JB.00347-06","article-title":"Two transsulfurylation pathways in Klebsiella pneumoniae","volume":"188","author":"Seiflein","year":"2006","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.bcp.2017.09.010_b0245","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1126\/science.1209855","article-title":"H2S: a universal defense against antibiotics in bacteria","volume":"334","author":"Shatalin","year":"2011","journal-title":"Science"},{"key":"10.1016\/j.bcp.2017.09.010_b0250","doi-asserted-by":"crossref","first-page":"6022","DOI":"10.1073\/pnas.1703576114","article-title":"Mechanism of H2S-mediated protection against oxidative stress in Escherichia coli","volume":"114","author":"Mironov","year":"2017","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bcp.2017.09.010_b0255","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1002\/pro.3123","article-title":"Crystallographic and mutational analyses of cystathionine \u03b2-synthase in the H2S-synthetic gene cluster in Lactobacillus plantarum","volume":"26","author":"Matoba","year":"2017","journal-title":"Protein Sci."},{"key":"10.1016\/j.bcp.2017.09.010_b0260","doi-asserted-by":"crossref","first-page":"R592","DOI":"10.1152\/ajpregu.00421.2012","article-title":"Thiosulfate: a readily accessible source of hydrogen sulfide in oxygen sensing","volume":"305","author":"Olson","year":"2013","journal-title":"Am J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.bcp.2017.09.010_b0265","doi-asserted-by":"crossref","first-page":"1494","DOI":"10.1111\/bph.12825","article-title":"Exogenous administration of thiosulfate, a donor of hydrogen sulfide, attenuates angiotensin II-induced hypertensive heart disease in rats","volume":"172","author":"Snijder","year":"2015","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.bcp.2017.09.010_b0270","first-page":"233","article-title":"The possible role of hydrogen sulfide in human periodontal disease. I. Hydrogen sulfide production in periodontal pockets","volume":"5","author":"Rizzo","year":"1967","journal-title":"Periodontics"},{"key":"10.1016\/j.bcp.2017.09.010_b0275","first-page":"59","article-title":"Hydrogen sulfide and periodontal disease","volume":"20","author":"Horowitz","year":"1972","journal-title":"Periodontal. Abstr."},{"key":"10.1016\/j.bcp.2017.09.010_b0280","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1016\/0003-9969(81)90104-7","article-title":"Characterization of volatile sulphur production by pathogenic and non-pathogenic strains of oral Bacteroides","volume":"26","author":"Tonzetich","year":"1981","journal-title":"Arch. Oral Biol."},{"key":"10.1016\/j.bcp.2017.09.010_b0285","first-page":"CD006701","article-title":"Mouthrinses for the treatment of halitosis","volume":"8","author":"Fedorowicz","year":"2008","journal-title":"Cochrane Database Syst. Rev."},{"key":"10.1016\/j.bcp.2017.09.010_b0290","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1016\/S0003-9969(99)00056-4","article-title":"Negative correlation between oral malodour and numbers and activities of sulphate-reducing bacteria in the human mouth","volume":"44","author":"Willis","year":"1999","journal-title":"Arch. Oral Biol."},{"key":"10.1016\/j.bcp.2017.09.010_b0295","doi-asserted-by":"crossref","first-page":"427","DOI":"10.4103\/0972-0707.168794","article-title":"Enamel surface changes caused by hydrogen sulfide","volume":"18","author":"Yamaguchi","year":"2015","journal-title":"J. Conserv. Dent."},{"key":"10.1016\/j.bcp.2017.09.010_b0300","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1111\/j.1476-5381.2009.00248.x","article-title":"Detection of exhaled hydrogen sulphide gas in rats exposed to intravenous sodium sulphide","volume":"157","author":"Insko","year":"2009","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.bcp.2017.09.010_b0305","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1111\/j.1365-2125.2010.03636.x","article-title":"Detection of exhaled hydrogen sulphide gas in healthy human volunteers during intravenous administration of sodium sulphide","volume":"69","author":"Toombs","year":"2010","journal-title":"Br. J. Clin. Pharmacol."},{"key":"10.1016\/j.bcp.2017.09.010_b0310","first-page":"G1028","article-title":"Insights into human colonic physiology obtained from the study of flatus composition","volume":"272","author":"Suarez","year":"1997","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.bcp.2017.09.010_b0315","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1111\/j.1572-0241.1998.083_c.x","article-title":"Fecal hydrogen sulfide pro- duction in ulcerative colitis","volume":"93","author":"Levine","year":"1998","journal-title":"Am. J. Gastroenterol."},{"key":"10.1016\/j.bcp.2017.09.010_b0320","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1038\/nrgastro.2012.85","article-title":"Contributions of the microbial hydrogen economy to colonic homeostasis","volume":"9","author":"Carbonero","year":"2012","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"10.1016\/j.bcp.2017.09.010_b0325","doi-asserted-by":"crossref","DOI":"10.1136\/gutjnl-2016-313321","article-title":"Race-dependent association of sulfidogenic bacteria with colorectal cancer","author":"Yazici","year":"2017","journal-title":"Gut"},{"key":"10.1016\/j.bcp.2017.09.010_b0330","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1016\/j.ajpath.2016.11.015","article-title":"Changes in the luminal environment of the colonic epithelial cells and physiopathological consequences","volume":"187","author":"Blachier","year":"2017","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.bcp.2017.09.010_b0335","doi-asserted-by":"crossref","first-page":"2099","DOI":"10.1111\/bph.12369","article-title":"Regulation of mitochondrial bioenergetic function by hydrogen sulfide. Part I. Biochemical and physiological mechanisms","volume":"171","author":"Szabo","year":"2014","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.bcp.2017.09.010_b0340","doi-asserted-by":"crossref","first-page":"E1558","DOI":"10.3390\/molecules21111558","article-title":"Gut bacteria and hydrogen sulfide: the new old players in circulatory system homeostasis","volume":"21","author":"Tomasova","year":"2016","journal-title":"Molecules"},{"key":"10.1016\/j.bcp.2017.09.010_b0345","doi-asserted-by":"crossref","first-page":"S46","DOI":"10.1016\/j.niox.2015.02.112","article-title":"Systemic infection and combined burn and infection: Contribution of host-derived and bacteria-derived hydrogen sulfide production to bacterial clearance","volume":"47","author":"Toliver-Kinsky","year":"2015","journal-title":"Nitric Oxide"},{"key":"10.1016\/j.bcp.2017.09.010_b0350","first-page":"683","article-title":"Release of hydrogen sulfide into an atmosphere containing sulfur dioxide","volume":"266","author":"De Cormis","year":"1968","journal-title":"CR Acad. Sci."},{"key":"10.1016\/j.bcp.2017.09.010_b0355","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.niox.2016.04.002","article-title":"Biological consilience of hydrogen sulfide and nitric oxide in plants: Gases of primordial earth linking plant, microbial and animal physiologies","volume":"55\u201356","author":"Yamasaki","year":"2016","journal-title":"Nitric Oxide"},{"key":"10.1016\/j.bcp.2017.09.010_b0360","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1007\/BF00367496","article-title":"The sulfide system: a new biotic community underneath the oxidized layer of marine sand bottoms","volume":"7","author":"Fenchel","year":"1970","journal-title":"Mar. Biol."},{"key":"10.1016\/j.bcp.2017.09.010_b0365","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1128\/AEM.41.2.528-538.1981","article-title":"Morphological survey of microbial mats near deep-sea thermal vents","volume":"41","author":"Jannasch","year":"1981","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.bcp.2017.09.010_b0370","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1126\/science.229.4715.717","article-title":"Geomicrobiology of deep-sea hydrothermal vents","volume":"229","author":"Jannasch","year":"1985","journal-title":"Science"},{"key":"10.1016\/j.bcp.2017.09.010_b0375","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1096\/fasebj.7.6.8472894","article-title":"Aspects of life development at deep sea hydrothermal vents","volume":"7","author":"Gaill","year":"1993","journal-title":"FASEB J."},{"key":"10.1016\/j.bcp.2017.09.010_b0380","doi-asserted-by":"crossref","first-page":"e00279","DOI":"10.1128\/mBio.00279-11","article-title":"Life and death of deep-sea vents: bacterial diversity and ecosystem succession on inactive hydrothermal sulfides","volume":"3","author":"Sylvan","year":"2012","journal-title":"MBio"},{"key":"10.1016\/j.bcp.2017.09.010_b0385","doi-asserted-by":"crossref","first-page":"2609","DOI":"10.1242\/jeb.200.20.2609","article-title":"Sulfide acquisition by the vent worm Riftia pachyptila appears to be via uptake of HS\u2212, rather than H2S","volume":"200","author":"Goffredi","year":"1997","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.bcp.2017.09.010_b0390","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1007\/s11084-010-9217-y","article-title":"A suggested pioneer organism for the W\u00e4chtersh\u00e4user origin of life hypothesis","volume":"41","author":"Kundell","year":"2011","journal-title":"Orig. Life Evol. Biosph."},{"key":"10.1016\/j.bcp.2017.09.010_b0395","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1007\/s11084-012-9315-0","article-title":"Open questions on the origin of life at anoxic geothermal fields","volume":"42","author":"Mulkidjanian","year":"2012","journal-title":"Orig. Life Evol. Biosph."},{"key":"10.1016\/j.bcp.2017.09.010_b0400","doi-asserted-by":"crossref","first-page":"20618","DOI":"10.1073\/pnas.0710191104","article-title":"Hydrogen sulfide increases thermotolerance and lifespan in Caenorhabditis elegans","volume":"104","author":"Miller","year":"2007","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bcp.2017.09.010_b0405","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1042\/BJ20111478","article-title":"Novel structural arrangement of nematode cystathionine \u03b2-synthases: characterization of Caenorhabditis elegans CBS-1","volume":"443","author":"Vozdek","year":"2012","journal-title":"Biochem. J."},{"key":"10.1016\/j.bcp.2017.09.010_b0410","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1016\/j.neuron.2011.12.037","article-title":"CYSL-1 interacts with the O2-sensing hydroxylase EGL-9 to promote H2S-modulated hypoxia-induced behavioral plasticity in C. elegans","volume":"73","author":"Ma","year":"2012","journal-title":"Neuron"},{"key":"10.1016\/j.bcp.2017.09.010_b0415","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4149\/gpb_2013001","article-title":"Hydrogen sulfide in cell signaling, signal transduction, cellular bioenergetics and physiology in C. elegans","volume":"32","author":"M\u00f3dis","year":"2013","journal-title":"Gen. Physiol. Biophys."},{"key":"10.1016\/j.bcp.2017.09.010_b0420","doi-asserted-by":"crossref","first-page":"2621","DOI":"10.1089\/ars.2013.5448","article-title":"Hydrogen sulfide is an endogenous regulator of aging in Caenorhabditis elegans","volume":"20","author":"Qabazard","year":"2014","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.bcp.2017.09.010_b0425","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.cell.2014.11.048","article-title":"Endogenous hydrogen sulfide production is essential for dietary restriction benefits","volume":"160","author":"Hine","year":"2015","journal-title":"Cell"},{"key":"10.1016\/j.bcp.2017.09.010_b0430","doi-asserted-by":"crossref","first-page":"E2832","DOI":"10.1073\/pnas.1524727113","article-title":"Roles for ROS and hydrogen sulfide in the longevity response to germline loss in Caenorhabditis elegans","volume":"113","author":"Wei","year":"2016","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bcp.2017.09.010_b0435","unstructured":"Klaus Hofmann: Vincent du Vigneaud (1901-1978): A Biographical Memoir. National Academy of Sciences."},{"key":"10.1016\/j.bcp.2017.09.010_b0440","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/S0021-9258(18)75518-X","article-title":"The oxidation of the sulfur of homocystine, methionine, and S-methylcysteine in the animal body","volume":"105","author":"du Vigneaud","year":"1934","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bcp.2017.09.010_b0445","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S0021-9258(18)72659-8","article-title":"The synthesis of ll-S-(\u03b2-amino-\u03b2carboxyethyl) homocysteine and the replacement by it of cystine in the diet","volume":"143","author":"du Vigneaud","year":"1942","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bcp.2017.09.010_b0450","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/S0021-9258(18)72535-0","article-title":"The formation of cysteine from homocysteine and serine by liver tissue of rats","volume":"144","author":"Binkley","year":"1942","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bcp.2017.09.010_b0455","first-page":"801","article-title":"Intermediary sulfur metabolism. III. Formation of hydrogen sulfide from cystine and cysteine by the liver","volume":"7","author":"Hanson","year":"1952","journal-title":"Z Gesamte Inn. Med."},{"key":"10.1016\/j.bcp.2017.09.010_b0460","first-page":"415","article-title":"Role of transamination and pyridoxal phosphate in the enzymatic formation of hydrogen sulfide from cysteine by the rat liver under anaerobiosis","volume":"38","author":"Chatagner","year":"1956","journal-title":"Bull. Soc. Chim. Biol. (Paris)"},{"key":"10.1016\/j.bcp.2017.09.010_b0465","doi-asserted-by":"crossref","first-page":"2141","DOI":"10.1016\/S0021-9258(18)69881-3","article-title":"Enzymatic formation of polysulfides from mercaptopyruvate","volume":"234","author":"Hylin","year":"1959","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bcp.2017.09.010_b0470","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/0005-2744(69)90173-9","article-title":"Reactions catalysed by serine sulfhydrase from chicken liver","volume":"171","author":"Braunstein","year":"1971","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bcp.2017.09.010_b0475","first-page":"271","article-title":"Cleavage of cystine by cystathionase","volume":"43","author":"Costa","year":"1972","journal-title":"Enzymologia"},{"key":"10.1016\/j.bcp.2017.09.010_b0480","first-page":"401","article-title":"Effects of several unusual sulfur-containing amino acids on rat liver cystathionine-gamma-lyase","volume":"7","author":"Yao","year":"1975","journal-title":"Physiol. Chem. Phys."},{"key":"10.1016\/j.bcp.2017.09.010_b0485","doi-asserted-by":"crossref","first-page":"1617","DOI":"10.1073\/pnas.72.4.1617","article-title":"Beta-cyanoalanine synthase: purification and characterization","volume":"72","author":"Akopyan","year":"1975","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bcp.2017.09.010_b0490","first-page":"509","article-title":"Methionine adenosyltransferase, cystathionine beta-synthase and cystathionine gamma-lyase activity of rat liver subcellular particles, human blood cells and mixed white cells from rat bone marrow","volume":"48","author":"Allsop","year":"1975","journal-title":"Clin. Sci. Mol. Med. Suppl."},{"key":"10.1016\/j.bcp.2017.09.010_b0495","first-page":"241","article-title":"Desulfuration of l-cysteine through transamination and transsulfuration in rat liver","volume":"9","author":"Ubuka","year":"1977","journal-title":"Physiol. Chem. Phys."},{"key":"10.1016\/j.bcp.2017.09.010_b0500","doi-asserted-by":"crossref","unstructured":"Kimura H. Hydrogen sulfide and polysulfide signaling. Antioxid Redox Signal. in press, 2017.","DOI":"10.1089\/ars.2017.7076"},{"key":"10.1016\/j.bcp.2017.09.010_b0505","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1042\/bj2060267","article-title":"Characterization of the enzymic capacity for cysteine desulphhydration in liver and kidney of the rat","volume":"206","author":"Stipanuk","year":"1982","journal-title":"Biochem. J."},{"key":"10.1016\/j.bcp.2017.09.010_b0510","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1159\/000241634","article-title":"Developmental pattern, tissue distribution, and subcellular distribution of cysteine: alpha-ketoglutarate aminotransferase and 3-mercaptopyruvate sulfurtransferase activities in the rat","volume":"43","author":"Kuo","year":"1983","journal-title":"Biol. Neonate"},{"key":"10.1016\/j.bcp.2017.09.010_b0515","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1016\/0006-2952(89)90288-8","article-title":"Acute hydrogen sulfide poisoning. Demonstration of selective uptake of sulfide by the brainstem by measurement of brain sulfide levels","volume":"38","author":"Warenycia","year":"1989","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.bcp.2017.09.010_b0520","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1093\/jat\/13.2.105","article-title":"Determination of sulfide in brain tissue by gas dialysis\/ion chromatography: postmortem studies and two case reports","volume":"13","author":"Goodwin","year":"1989","journal-title":"J. Anal. Toxicol."},{"key":"10.1016\/j.bcp.2017.09.010_b0525","doi-asserted-by":"crossref","DOI":"10.1016\/S0378-4347(00)82537-2","article-title":"Determination of sulfides in brain tissue and rumen fluid by ion-interaction reversed-phase high-performance liquid chromatography","volume":"526","author":"Savage","year":"1990","journal-title":"J. Chromatogr."},{"key":"10.1016\/j.bcp.2017.09.010_b0530","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1523\/JNEUROSCI.16-03-01066.1996","article-title":"The possible role of hydrogen sulfide as an endogenous neuromodulator","volume":"16","author":"Abe","year":"1996","journal-title":"J Neurosci"},{"key":"10.1016\/j.bcp.2017.09.010_b0535","first-page":"116","article-title":"The rotten smell of memory: it's a gas","volume":"149","author":"Snyder","year":"1996","journal-title":"Sci. News"},{"key":"10.1016\/j.bcp.2017.09.010_b0540","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1006\/bbrc.1997.6878","article-title":"The possible role of hydrogen sulfide as an endogenous smooth muscle relaxant in synergy with nitric oxide","volume":"237","author":"Hosoki","year":"1997","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bcp.2017.09.010_b0545","doi-asserted-by":"crossref","first-page":"6008","DOI":"10.1093\/emboj\/20.21.6008","article-title":"The vasorelaxant effect of H2S as a novel endogenous gaseous KATP channel opener","volume":"20","author":"Zhao","year":"2001","journal-title":"EMBO J."},{"key":"10.1016\/j.bcp.2017.09.010_b0550","doi-asserted-by":"crossref","first-page":"H474","DOI":"10.1152\/ajpheart.00013.2002","article-title":"H2S-induced vasorelaxation and underlying cellular and molecular mechanisms","volume":"283","author":"Zhao","year":"2002","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.bcp.2017.09.010_b0555","doi-asserted-by":"crossref","first-page":"1757","DOI":"10.1124\/mol.105.017467","article-title":"Direct stimulation of KATP channels by exogenous and endogenous hydrogen sulfide in vascular smooth muscle cells","volume":"68","author":"Tang","year":"2005","journal-title":"Mol. Pharmacol."},{"key":"10.1016\/j.bcp.2017.09.010_b0560","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1126\/science.1162667","article-title":"H2S as a physiologic vasorelaxant: hypertension in mice with deletion of cystathionine gamma-lyase","volume":"322","author":"Yang","year":"2008","journal-title":"Science"},{"key":"10.1016\/j.bcp.2017.09.010_b0565","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1161\/CIRCRESAHA.111.240242","article-title":"Hydrogen sulfide as endothelium-derived hyperpolarizing factor sulfhydrates potassium channels","volume":"109","author":"Mustafa","year":"2011","journal-title":"Circ. Res."},{"key":"10.1016\/j.bcp.2017.09.010_b0570","doi-asserted-by":"crossref","first-page":"1792","DOI":"10.1096\/fj.02-0211hyp","article-title":"Two's company, three's a crowd: can H2S be the third endogenous gaseous transmitter?","volume":"16","author":"Wang","year":"2002","journal-title":"FASEB J."},{"key":"10.1016\/j.bcp.2017.09.010_b0575","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1089\/152308603768295249","article-title":"The gasotransmitter role of hydrogen sulfide","volume":"5","author":"Wang","year":"2003","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.bcp.2017.09.010_b0580","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1097\/MNH.0b013e3283430651","article-title":"Signaling pathways for the vascular effects of hydrogen sulfide","volume":"20","author":"Wang","year":"2011","journal-title":"Curr. Opin. Nephrol. Hypertens."},{"key":"10.1016\/j.bcp.2017.09.010_b0585","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1152\/physrev.00017.2011","article-title":"Physiological implications of hydrogen sulfide: a whiff exploration that blossomed","volume":"92","author":"Wang","year":"2012","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.bcp.2017.09.010_b0590","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1016\/j.bbrc.2004.04.094","article-title":"Endogenous hydrogen sulfide regulation of myocardial injury induced by isoproterenol","volume":"318","author":"Geng","year":"2004","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bcp.2017.09.010_b0595","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1096\/fj.04-1815fje","article-title":"Hydrogen sulfide protects neurons from oxidative stress","volume":"18","author":"Kimura","year":"2004","journal-title":"FASEB J."},{"key":"10.1016\/j.bcp.2017.09.010_b0600","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1111\/j.1471-4159.2004.02617.x","article-title":"The novel neuromodulator hydrogen sulfide: an endogenous peroxynitrite 'scavenger'?","volume":"90","author":"Whiteman","year":"2004","journal-title":"J. Neurochem."},{"key":"10.1016\/j.bcp.2017.09.010_b0605","doi-asserted-by":"crossref","first-page":"H2316","DOI":"10.1152\/ajpheart.00331.2004","article-title":"Hydrogen sulfide-induced relaxation of resistance mesenteric artery beds of rats","volume":"287","author":"Cheng","year":"2004","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.bcp.2017.09.010_b0610","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.1096\/fj.04-3583fje","article-title":"Hydrogen sulfide is a novel mediator of lipopolysaccharide-induced inflammation in the mouse","volume":"19","author":"Li","year":"2005","journal-title":"FASEB J."},{"key":"10.1016\/j.bcp.2017.09.010_b0615","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1002\/hep.20817","article-title":"The third gas: H2S regulates perfusion pressure in both the isolated and perfused normal rat liver and in cirrhosis","volume":"42","author":"Fiorucci","year":"2005","journal-title":"Hepatology"},{"key":"10.1016\/j.bcp.2017.09.010_b0620","doi-asserted-by":"crossref","first-page":"1210","DOI":"10.1053\/j.gastro.2005.07.060","article-title":"Inhibition of hydrogen sulfide generation contributes to gastric injury caused by anti-inflammatory nonsteroidal drugs","volume":"129","author":"Fiorucci","year":"2005","journal-title":"Gastroenterology"},{"key":"10.1016\/j.bcp.2017.09.010_b0625","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.freeradbiomed.2006.03.021","article-title":"Hydrogen sulfide inhibits nitric oxide production and nuclear factor-kappaB via heme oxygenase-1 expression in RAW264.7 macrophages stimulated with lipopolysaccharide","volume":"41","author":"Oh","year":"2006","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.bcp.2017.09.010_b0630","doi-asserted-by":"crossref","first-page":"2118","DOI":"10.1096\/fj.06-6270fje","article-title":"Hydrogen sulfide is an endogenous modulator of leukocyte-mediated inflammation","volume":"20","author":"Zanardo","year":"2006","journal-title":"FASEB J."},{"key":"10.1016\/j.bcp.2017.09.010_b0635","doi-asserted-by":"crossref","first-page":"15560","DOI":"10.1073\/pnas.0705891104","article-title":"Hydrogen sulfide attenuates myocardial ischemia-reperfusion injury by preservation of mitochondrial function","volume":"104","author":"Elrod","year":"2007","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bcp.2017.09.010_b0640","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.cardiores.2007.05.026","article-title":"The novel proangiogenic effect of hydrogen sulfide is dependent on Akt phosphorylation","volume":"76","author":"Cai","year":"2007","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.bcp.2017.09.010_b0645","doi-asserted-by":"crossref","first-page":"17977","DOI":"10.1073\/pnas.0705710104","article-title":"Hydrogen sulfide mediates the vasoactivity of garlic","volume":"104","author":"Benavides","year":"2007","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bcp.2017.09.010_b0650","doi-asserted-by":"crossref","first-page":"2351","DOI":"10.1161\/CIRCULATIONAHA.107.753467","article-title":"Characterization of a novel, water-soluble hydrogen sulfide-releasing molecule (GYY4137): new insights into the biology of hydrogen sulfide","volume":"117","author":"Li","year":"2008","journal-title":"Circulation"},{"key":"10.1016\/j.bcp.2017.09.010_b0655","doi-asserted-by":"crossref","first-page":"R1479","DOI":"10.1152\/ajpregu.90566.2008","article-title":"Whole tissue hydrogen sulfide concentrations are orders of magnitude lower than presently accepted values","volume":"295","author":"Furne","year":"2008","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.bcp.2017.09.010_b0660","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1089\/ars.2008.2132","article-title":"A source of hydrogen sulfide and a mechanism of its release in the brain","volume":"11","author":"Ishigami","year":"2009","journal-title":"Antioxid. Redox. Signal."},{"key":"10.1016\/j.bcp.2017.09.010_b0665","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1161\/ATVBAHA.108.179333","article-title":"Role of H2S in the development of atherosclerotic lesions in apolipoprotein E knockout mice","volume":"29","author":"Wang","year":"2009","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.bcp.2017.09.010_b0670","doi-asserted-by":"crossref","first-page":"11601","DOI":"10.1074\/jbc.M808026200","article-title":"H2S biogenesis by human cystathionine gamma-lyase leads to the novel sulfur metabolites lanthionine and homolanthionine and is responsive to the grade of hyperhomocysteinemia","volume":"284","author":"Chiku","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bcp.2017.09.010_b0675","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1089\/ars.2008.2253","article-title":"3-Mercaptopyruvate sulfurtransferase produces hydrogen sulfide and bound sulfane sulfur in the brain","volume":"11","author":"Shibuya","year":"2009","journal-title":"Antioxid. Redox. Signal."},{"key":"10.1016\/j.bcp.2017.09.010_b0680","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1161\/CIRCRESAHA.109.199919","article-title":"Hydrogen sulfide mediates cardioprotection through Nrf2 signaling","volume":"105","author":"Calvert","year":"2009","journal-title":"Circ. Res."},{"key":"10.1016\/j.bcp.2017.09.010_b0685","doi-asserted-by":"crossref","first-page":"22457","DOI":"10.1074\/jbc.M109.010868","article-title":"Relative contributions of cystathionine beta-synthase and gamma-cystathionase to H2S biogenesis via alternative trans-sulfuration reactions","volume":"284","author":"Singh","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bcp.2017.09.010_b0690","doi-asserted-by":"crossref","DOI":"10.1126\/scisignal.2000464","article-title":"H2S signals through protein S-sulfhydration","volume":"2","author":"Mustafa","year":"2009","journal-title":"Sci. Signal."},{"key":"10.1016\/j.bcp.2017.09.010_b0695","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1093\/jb\/mvp111","article-title":"Vascular endothelium expresses 3-mercaptopyruvate sulfurtransferase and produces hydrogen sulfide","volume":"146","author":"Shibuya","year":"2009","journal-title":"J. Biochem."},{"key":"10.1016\/j.bcp.2017.09.010_b0700","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1089\/ars.2008.2282","article-title":"Hydrogen sulfide increases glutathione production and suppresses oxidative stress in mitochondria","volume":"12","author":"Kimura","year":"2010","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.bcp.2017.09.010_b0705","doi-asserted-by":"crossref","first-page":"10719","DOI":"10.1073\/pnas.1005866107","article-title":"H2S mediates O2 sensing in the carotid body","volume":"107","author":"Peng","year":"2010","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bcp.2017.09.010_b0710","doi-asserted-by":"crossref","DOI":"10.1126\/scisignal.2002329","article-title":"H2S-Induced sulfhydration of the phosphatase PTP1B and its role in the endoplasmic reticulum stress response","volume":"4","author":"Krishnan","year":"2011","journal-title":"Sci. Signal."},{"key":"10.1016\/j.bcp.2017.09.010_b0715","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.molcel.2011.10.021","article-title":"Hydrogen sulfide-linked sulfhydration of NF-\u03baB mediates its antiapoptotic actions","volume":"45","author":"Sen","year":"2012","journal-title":"Mol. Cell"},{"key":"10.1016\/j.bcp.2017.09.010_b0720","doi-asserted-by":"crossref","first-page":"2943","DOI":"10.1073\/pnas.1115634109","article-title":"Hydrogen sulfide (H2S) metabolism in mitochondria and its regulatory role in energy production","volume":"109","author":"Fu","year":"2012","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bcp.2017.09.010_b0725","doi-asserted-by":"crossref","first-page":"9161","DOI":"10.1073\/pnas.1202916109","article-title":"Hydrogen sulfide and nitric oxide are mutually dependent in the regulation of angiogenesis and endothelium-dependent vasorelaxation","volume":"109","author":"Coletta","year":"2012","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bcp.2017.09.010_b0730","doi-asserted-by":"crossref","first-page":"12016","DOI":"10.1021\/ja3009693","article-title":"Chemical characterization of the smallest S-nitrosothiol, HSNO; cellular cross-talk of H2S and S-nitrosothiols","volume":"134","author":"Filipovic","year":"2012","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.bcp.2017.09.010_b0735","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1096\/fj.12-216507","article-title":"Intramitochondrial H2S production by 3-mercaptopyruvate sulfurtransferase maintains mitochondrial electron flow and supports cellular bioenergetics","volume":"27","author":"M\u00f3dis","year":"2013","journal-title":"FASEB J."},{"key":"10.1016\/j.bcp.2017.09.010_b0740","doi-asserted-by":"crossref","first-page":"2451","DOI":"10.1096\/fj.12-226415","article-title":"Polysulfides are possible H2S-derived signaling molecules in rat brain","volume":"27","author":"Kimura","year":"2013","journal-title":"FASEB J."},{"key":"10.1016\/j.bcp.2017.09.010_b0745","doi-asserted-by":"crossref","first-page":"922","DOI":"10.1111\/bph.12171","article-title":"Selectivity of commonly used pharmacological inhibitors for cystathionine \u03b2 synthase (CBS) and cystathionine \u03b3 lyase (CSE)","volume":"169","author":"Asimakopoulou","year":"2013","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.bcp.2017.09.010_b0750","doi-asserted-by":"crossref","first-page":"12474","DOI":"10.1073\/pnas.1306241110","article-title":"Tumor-derived hydrogen sulfide, produced by cystathionine-\u03b2-synthase, stimulates bioenergetics, cell proliferation, and angiogenesis in colon cancer","volume":"110","author":"Szabo","year":"2013","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bcp.2017.09.010_b0755","doi-asserted-by":"crossref","first-page":"1366","DOI":"10.1038\/ncomms2371","article-title":"A novel pathway for the production of H2S from D-cysteine in mammalian cells","volume":"4","author":"Shibuya","year":"2013","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bcp.2017.09.010_b0760","doi-asserted-by":"crossref","first-page":"3182","DOI":"10.1073\/pnas.1321871111","article-title":"H2S cytoprotective signaling is endothelial nitric oxide synthase-nitric oxide dependent","volume":"111","author":"King","year":"2014","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bcp.2017.09.010_b0765","doi-asserted-by":"crossref","first-page":"4381","DOI":"10.1038\/ncomms5381","article-title":"H2S and NO cooperatively regulate vascular tone by activating a neuroendocrine HNO-TRPA1-CGRP signalling pathway","volume":"5","author":"Eberhardt","year":"2014","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bcp.2017.09.010_b0770","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.bbrc.2006.02.154","article-title":"Evidence for the formation of a novel nitrosothiol from the gaseous mediators nitric oxide and hydrogen sulphide","volume":"343","author":"Whiteman","year":"2006","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bcp.2017.09.010_b0775","doi-asserted-by":"crossref","first-page":"E4651","DOI":"10.1073\/pnas.1509277112","article-title":"Key bioactive reaction products of the NO\/H2S interaction are S\/N-hybrid species, polysulfides, and nitroxyl","volume":"112","author":"Cortese-Krott","year":"2015","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bcp.2017.09.010_b0780","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.niox.2014.04.008","article-title":"AP39, a novel mitochondria-targeted hydrogen sulfide donor, stimulates cellular bioenergetics, exerts cytoprotective effects and protects against the loss of mitochondrial DNA integrity in oxidatively stressed endothelial cells in vitro","volume":"41","author":"Szczesny","year":"2014","journal-title":"Nitric Oxide"},{"key":"10.1016\/j.bcp.2017.09.010_b0785","doi-asserted-by":"crossref","first-page":"36125","DOI":"10.1038\/srep36125","article-title":"Inhibition of hydrogen sulfide biosynthesis sensitizes lung adenocarcinoma to chemotherapeutic drugs by inhibiting mitochondrial DNA repair and suppressing cellular bioenergetics","volume":"6","author":"Szczesny","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bcp.2017.09.010_b0790","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/S1096-4959(01)00309-8","article-title":"Sulfide oxidation coupled to ATP synthesis in chicken liver mitochondria","volume":"129","author":"Yong","year":"2011","journal-title":"Comp. Biochem. Physiol. B Biochem. Mol. Biol."},{"key":"10.1016\/j.bcp.2017.09.010_b0795","doi-asserted-by":"crossref","first-page":"1699","DOI":"10.1096\/fj.06-7407com","article-title":"Sulfide, the first inorganic substrate for human cells","volume":"21","author":"Goubern","year":"2007","journal-title":"FASEB J."},{"key":"10.1016\/j.bcp.2017.09.010_b0800","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1038\/162770a0","article-title":"Structure of dinitrososulphite ion","volume":"162","author":"Cox","year":"1948","journal-title":"Nature"},{"key":"10.1016\/j.bcp.2017.09.010_b0805","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1002\/zaac.19562850305","article-title":"Zur Kenntnis der Salze der Nitrosohydroxylaminsulfons\u00e4ure. I. Chemischer Konstitutionsbeweis der Nitrosohydroxylaminsulfonate","volume":"285","author":"Degener","year":"1956","journal-title":"Z. Anorg. Allg. Chem."},{"key":"10.1016\/j.bcp.2017.09.010_b0810","first-page":"497","article-title":"The effect of hydrogen sulfide baths on the circulation and the processes of functional adaptation in dogs with experimental atherosclerosis","volume":"31","author":"Chepikova","year":"1966","journal-title":"Vopr Kurortol Fizioter Lech Fiz Kult"},{"key":"10.1016\/j.bcp.2017.09.010_b0815","first-page":"313","article-title":"The effect of Matsesta hydrogen sulfide baths on the status of the myocardium and coronary arteries in experimental atherosclerosis","volume":"33","author":"Lavrov","year":"1968","journal-title":"Vopr Kurortol Fizioter Lech Fiz Kult"},{"key":"10.1016\/j.bcp.2017.09.010_b0820","first-page":"315","article-title":"Effect of hydrogen sulfide baths on the activity of tissue cytochrome oxidase in rabbits with experimental arteriosclerosis","volume":"35","author":"Kubli","year":"1970","journal-title":"Vopr Kurortol Fizioter Lech Fiz Kult"},{"key":"10.1016\/j.bcp.2017.09.010_b0825","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1039\/C3MD00323J","article-title":"The synthesis and functional evaluation of a mitochondria-targeted hydrogen sulfide donor, (10-oxo-10-(4-(3-thioxo-3H-1,2-dithiol-5-yl)phenoxy)decyl) triphenylphosphonium bromide (AP39)","volume":"5","author":"Le Trionnaire","year":"2014","journal-title":"J. Med. Chem. Comm."},{"key":"10.1016\/j.bcp.2017.09.010_b0830","article-title":"Hydrogen sulfide-releasing therapeutics: translation to the clinic","author":"Wallace","year":"2017","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.bcp.2017.09.010_b0835","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1038\/nrd2425","article-title":"Hydrogen sulphide and its therapeutic potential","volume":"6","author":"Szabo","year":"2017","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.bcp.2017.09.010_b0840","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1146\/annurev-pharmtox-010510-100505","article-title":"Hydrogen sulfide and cell signaling","volume":"51","author":"Li","year":"2011","journal-title":"Ann. Rev. Pharmacol. Toxicol."},{"key":"10.1016\/j.bcp.2017.09.010_b0845","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1042\/CS20110267","article-title":"Emerging role of hydrogen sulfide in health and disease: critical appraisal of biomarkers and pharmacological tools","volume":"121","author":"Whiteman","year":"2011","journal-title":"Clin. Sci. (Lond)"},{"key":"10.1016\/j.bcp.2017.09.010_b0850","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1089\/ars.2011.4401","article-title":"A practical look at the chemistry and biology of hydrogen sulfide","volume":"17","author":"Olson","year":"2012","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.bcp.2017.09.010_b0855","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.niox.2014.05.012","article-title":"Controversies and conundrums in hydrogen sulfide biology","volume":"41","author":"Olson","year":"2014","journal-title":"Nitric Oxide"},{"key":"10.1016\/j.bcp.2017.09.010_b0860","doi-asserted-by":"crossref","first-page":"1633","DOI":"10.1111\/bph.12806","article-title":"Pharmacological tools for hydrogen sulphide research: a brief, introductory guide for beginners","volume":"172","author":"Papapetropoulos","year":"2015","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.bcp.2017.09.010_b0865","series-title":"Chemistry, Biochemistry and Pharmacology of Hydrogen Sulfide (Handbook of Experimental Pharmacology)","year":"2016"},{"key":"10.1016\/j.bcp.2017.09.010_b0870","first-page":"60","article-title":"The role of hydrogen sulfide in evolution and the evolution of hydrogen sulfide in metabolism and signaling","volume":"31","author":"Olson","year":"2016","journal-title":"Physiol. (Bethesda)"},{"key":"10.1016\/j.bcp.2017.09.010_b0875","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.neuint.2009.08.008","article-title":"Hydrogen sulfide: a novel signaling molecule in the central nervous system","volume":"56","author":"Tan","year":"2010","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.bcp.2017.09.010_b0880","doi-asserted-by":"crossref","first-page":"109","DOI":"10.2174\/187152811794776295","article-title":"The neurophysiology of hydrogen sulfide","volume":"10","author":"Rong","year":"2011","journal-title":"Inflamm. Allergy Drug Targets"},{"key":"10.1016\/j.bcp.2017.09.010_b0885","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1021\/cn500185g","article-title":"Hydrogen sulfide: a neuromodulator and neuroprotectant in the central nervous system","volume":"5","author":"Zhang","year":"2014","journal-title":"ACS Chem. Neurosci."},{"key":"10.1016\/j.bcp.2017.09.010_b0890","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1007\/978-3-319-18144-8_9","article-title":"Hydrogen sulfide and neuroinflammation","volume":"230","author":"Kida","year":"2015","journal-title":"Handb. Exp. Pharmacol."},{"key":"10.1016\/j.bcp.2017.09.010_b0895","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1089\/ars.2014.5917","article-title":"Modes of physiologic H2S signaling in the brain and peripheral tissues","volume":"22","author":"Paul","year":"2015","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.bcp.2017.09.010_b0900","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1161\/CIRCRESAHA.114.300505","article-title":"Emergence of hydrogen sulfide as an endogenous gaseous signaling molecule in cardiovascular disease","volume":"114","author":"Polhemus","year":"2014","journal-title":"Circ. Res."},{"key":"10.1016\/j.bcp.2017.09.010_b0905","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1016\/j.tips.2015.05.007","article-title":"The role of H2S bioavailability in endothelial dysfunction","volume":"36","author":"Wang","year":"2015","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.bcp.2017.09.010_b0910","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1007\/978-3-319-18144-8_4","article-title":"H2S and blood vessels: an overview","volume":"230","author":"Yang","year":"2015","journal-title":"Handb. Exp. Pharmacol."},{"key":"10.1016\/j.bcp.2017.09.010_b0915","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1097\/MNH.0000000000000206","article-title":"Hydrogen sulfide in hypertension","volume":"25","author":"van Goor","year":"2016","journal-title":"Curr. Opin. Nephrol. Hypertens."},{"key":"10.1016\/j.bcp.2017.09.010_b0920","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.phrs.2016.08.026","article-title":"Regulation and role of endogenously produced hydrogen sulfide in angiogenesis","volume":"113","author":"Katsouda","year":"2016","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.bcp.2017.09.010_b0925","doi-asserted-by":"crossref","first-page":"C537","DOI":"10.1152\/ajpcell.00329.2016","article-title":"Vascular biology of hydrogen sulfide","volume":"312","author":"Kanagy","year":"2017","journal-title":"Am. J. Physiol. Cell. Physiol."},{"key":"10.1016\/j.bcp.2017.09.010_b0930","article-title":"Protein S-sulfhydration by hydrogen sulfide in cardiovascular system","author":"Meng","year":"2017","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.bcp.2017.09.010_b0935","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1053\/j.gastro.2006.02.033","article-title":"The emerging roles of hydrogen sulfide in the gastrointestinal tract and liver","volume":"131","author":"Fiorucci","year":"2006","journal-title":"Gastroenterology"},{"key":"10.1016\/j.bcp.2017.09.010_b0940","doi-asserted-by":"crossref","first-page":"9099","DOI":"10.3390\/molecules20059099","article-title":"Gaseous mediators nitric oxide and hydrogen sulfide in the mechanism of gastrointestinal integrity, protection and ulcer healing","volume":"20","author":"Magierowski","year":"2015","journal-title":"Molecules"},{"key":"10.1016\/j.bcp.2017.09.010_b0945","doi-asserted-by":"crossref","first-page":"866","DOI":"10.3390\/microorganisms3040866","article-title":"Hydrogen sulfide in physiology and diseases of the digestive tract","volume":"3","author":"Singh","year":"2015","journal-title":"Microorganisms"},{"key":"10.1016\/j.bcp.2017.09.010_b0950","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.niox.2015.01.005","article-title":"Hydrogen sulfide in renal physiology, disease and transplantation\u2013the smell of renal protection","volume":"46","author":"Koning","year":"2015","journal-title":"Nitric Oxide"},{"key":"10.1016\/j.bcp.2017.09.010_b0955","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1089\/ars.2015.6596","article-title":"Hydrogen sulfide in renal physiology and disease","volume":"25","author":"Feliers","year":"2016","journal-title":"Antioxid Redox Signal."},{"key":"10.1016\/j.bcp.2017.09.010_b0960","doi-asserted-by":"crossref","first-page":"385","DOI":"10.3389\/fphar.2016.00385","article-title":"The role of hydrogen sulfide in renal system","volume":"7","author":"Cao","year":"2016","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.bcp.2017.09.010_b0965","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1007\/s00360-012-0654-y","article-title":"Mitochondrial adaptations to utilize hydrogen sulfide for energy and signaling","volume":"182","author":"Olson","year":"2012","journal-title":"J. Comp. Physiol. B"},{"key":"10.1016\/j.bcp.2017.09.010_b0970","doi-asserted-by":"crossref","first-page":"2123","DOI":"10.1111\/bph.12368","article-title":"Regulation of mitochondrial bioenergetic function by hydrogen sulfide. Part II. Pathophysiological and therapeutic aspects","volume":"171","author":"M\u00f3dis","year":"2014","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.bcp.2017.09.010_b0975","doi-asserted-by":"crossref","first-page":"5653","DOI":"10.2174\/1381612820666140306095717","article-title":"Mitochondrial biogenesis: regulation by endogenous gases during inflammation and organ stress","volume":"20","author":"Suliman","year":"2014","journal-title":"Curr. Pharm. Des."},{"key":"10.1016\/j.bcp.2017.09.010_b0980","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1016\/j.bbapap.2014.01.002","article-title":"H2S and its role in redox signaling","volume":"1844","author":"Kabil","year":"2014","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bcp.2017.09.010_b0985","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1089\/ars.2014.5869","article-title":"Signaling molecules: hydrogen sulfide and polysulfide","volume":"22","author":"Kimura","year":"2015","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.bcp.2017.09.010_b0990","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1007\/978-3-319-18144-8_3","article-title":"Physiological roles of hydrogen sulfide and polysulfides","volume":"230","author":"Kimura","year":"2015","journal-title":"Handb. Exp. Pharmacol."},{"key":"10.1016\/j.bcp.2017.09.010_b0995","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/j.tibs.2015.08.007","article-title":"H2S: a novel gasotransmitter that signals by sulfhydration","volume":"40","author":"Paul","year":"2015","journal-title":"Trends Biochem. Sci."},{"key":"10.1016\/j.bcp.2017.09.010_b1000","doi-asserted-by":"crossref","first-page":"E1334","DOI":"10.3390\/molecules22081334","article-title":"H\u2082S-mediated protein S-sulfhydration: a prediction for its formation and regulation","volume":"22","author":"Ju","year":"2017","journal-title":"Molecules"},{"key":"10.1016\/j.bcp.2017.09.010_b1005","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1016\/j.jmb.2016.12.015","article-title":"Functional and molecular insights of hydrogen sulfide signaling and protein sulfhydration","volume":"429","author":"Sen","year":"2017","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.bcp.2017.09.010_b1010","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1089\/ars.2013.5339","article-title":"Enzymology of H2S biogenesis, decay and signaling","volume":"20","author":"Kabil","year":"2014","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.bcp.2017.09.010_b1015","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1007\/s00018-016-2406-8","article-title":"H2S biosynthesis and catabolism: new insights from molecular studies","volume":"74","author":"Rose","year":"2017","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.bcp.2017.09.010_b1020","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.cbpa.2017.02.021","article-title":"Catalytic promiscuity and heme-dependent redox regulation of H2S synthesis","volume":"37","author":"Banerjee","year":"2017","journal-title":"Curr. Opin. Chem. Biol."},{"key":"10.1016\/j.bcp.2017.09.010_b1025","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.niox.2013.07.001","article-title":"Chemical foundations of hydrogen sulfide biology","volume":"35","author":"Li","year":"2013","journal-title":"Nitric Oxide"},{"key":"10.1016\/j.bcp.2017.09.010_b1030","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.freeradbiomed.2014.09.007","article-title":"Redox chemistry and chemical biology of H2S, hydropersulfides, and derived species: implications of their possible biological activity and utility","volume":"77","author":"Ono","year":"2014","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.bcp.2017.09.010_b1035","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/bs.mie.2014.11.036","article-title":"Mechanistic chemical perspective of hydrogen sulfide signaling","volume":"554","author":"Nagy","year":"2015","journal-title":"Methods Enzymol."},{"key":"10.1016\/j.bcp.2017.09.010_b1040","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.abb.2016.09.018","article-title":"Biological chemistry of hydrogen sulfide and persulfides","volume":"617","author":"Cuevasanta","year":"2017","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.bcp.2017.09.010_b1045","doi-asserted-by":"crossref","first-page":"C3","DOI":"10.1152\/ajpcell.00282.2016","article-title":"Hydrogen sulfide, an enhancer of vascular nitric oxide signaling: mechanisms and implications","volume":"312","author":"Szabo","year":"2017","journal-title":"Am. J. Physiol. Cell. Physiol."},{"key":"10.1016\/j.bcp.2017.09.010_b1050","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/bs.acc.2016.07.005","article-title":"Hydrogen sulfide as a \u201cdouble-faced\u201d compound: one with pro- and antioxidant effect","volume":"78","author":"Olas","year":"2017","journal-title":"Adv. Clin. Chem."},{"key":"10.1016\/j.bcp.2017.09.010_b1055","doi-asserted-by":"crossref","DOI":"10.1111\/bph.13815","article-title":"Nitric oxide and hydrogen sulfide: the gasotransmitter paradigm of the vascular system","author":"Cirino","year":"2017","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.bcp.2017.09.010_b1060","doi-asserted-by":"crossref","first-page":"5908","DOI":"10.1039\/C5DT05034K","article-title":"Inorganic sulfur-nitrogen compounds: from gunpowder chemistry to the forefront of biological signaling","volume":"45","author":"Cortese-Krott","year":"2016","journal-title":"Dalton Trans."},{"key":"10.1016\/j.bcp.2017.09.010_b1065","doi-asserted-by":"crossref","unstructured":"C. Kevil, N.N. Cortese-Krott, P. Nagy, A. Papapetropoulos, M. Feelisch, C. Szabo, Cooperative interactions between NO and H2S: Chemistry, biology, physiology, pathophysiology, in: Ignarro L., Freeman B. (eds.), Nitric Oxide, Elsevier, 2017, pp. 57\u201384.","DOI":"10.1016\/B978-0-12-804273-1.00005-3"},{"key":"10.1016\/j.bcp.2017.09.010_b1070","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1089\/ars.2017.7083","article-title":"The reactive species interactome: evolutionary emergence, biological significance, and opportunities for redox metabolomics and personalized medicine","volume":"27","author":"Cortese-Krott","year":"2017","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.bcp.2017.09.010_b1075","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1016\/j.bcp.2012.10.019","article-title":"Biology and therapeutic potential of hydrogen sulfide and hydrogen sulfide-releasing chimeras","volume":"85","author":"Kashfi","year":"2013","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.bcp.2017.09.010_b1080","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1089\/ars.2013.5308","article-title":"Anti-cancer activity of new designer hydrogen sulfide-donating hybrids","volume":"20","author":"Kashfi","year":"2014","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.bcp.2017.09.010_b1085","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1007\/978-3-319-18144-8_17","article-title":"Phosphinodithioate and phosphoramidodithioate hydrogen sulfide donors","volume":"230","author":"Whiteman","year":"2015","journal-title":"Handb. Exp. Pharmacol."},{"key":"10.1016\/j.bcp.2017.09.010_b1090","doi-asserted-by":"crossref","DOI":"10.1124\/pr.117.014050","article-title":"International union of basic and clinical pharmacology. CII: pharmacological modulation of H2S levels: H2S donors and H2S biosynthesis inhibitors","author":"Szabo","year":"2017","journal-title":"Pharmacol. Rev."},{"key":"10.1016\/j.bcp.2017.09.010_b1095","doi-asserted-by":"crossref","first-page":"G467","DOI":"10.1152\/ajpgi.00169.2013","article-title":"Hydrogen sulfide-based therapeutics and gastrointestinal diseases: translating physiology to treatments","volume":"305","author":"Chan","year":"2013","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"key":"10.1016\/j.bcp.2017.09.010_b1100","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1038\/nrd4433","article-title":"Hydrogen sulfide-based therapeutics: exploiting a unique but ubiquitous gasotransmitter","volume":"14","author":"Wallace","year":"2015","journal-title":"Nat. Rev. Drug. Discov."},{"key":"10.1016\/j.bcp.2017.09.010_b1105","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.pharmthera.2015.04.004","article-title":"Hydrogen sulfide and cardioprotection\u2013Mechanistic insights and clinical translatability","volume":"152","author":"Salloum","year":"2015","journal-title":"Pharmacol. Ther."},{"key":"10.1016\/j.bcp.2017.09.010_b1110","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1038\/nrd.2015.1","article-title":"Gasotransmitters in cancer: from pathophysiology to experimental therapy","volume":"15","author":"Szabo","year":"2016","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.bcp.2017.09.010_b1115","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1016\/j.phrs.2016.07.041","article-title":"Hydrogen sulfide-releasing anti-inflammatory drugs for chemoprevention and treatment of cancer","volume":"111","author":"Ianaro","year":"2016","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.bcp.2017.09.010_b1120","doi-asserted-by":"crossref","first-page":"113","DOI":"10.4103\/2045-9912.208517","article-title":"Hydrogen sulfide therapy in brain diseases: from bench to bedside","volume":"7","author":"Zhang","year":"2017","journal-title":"Med. Gas Res."},{"key":"10.1016\/j.bcp.2017.09.010_b1125","article-title":"Toward hydrogen sulfide based therapeutics: critical drug delivery and developability issues","author":"Zheng","year":"2017","journal-title":"Med. Res. Rev."}],"container-title":["Biochemical Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006295217306068?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006295217306068?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,8,3]],"date-time":"2022-08-03T08:05:49Z","timestamp":1659513949000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006295217306068"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3]]},"references-count":225,"alternative-id":["S0006295217306068"],"URL":"https:\/\/doi.org\/10.1016\/j.bcp.2017.09.010","relation":{},"ISSN":["0006-2952"],"issn-type":[{"value":"0006-2952","type":"print"}],"subject":[],"published":{"date-parts":[[2018,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A timeline of hydrogen sulfide (H2S) research: From environmental toxin to biological mediator","name":"articletitle","label":"Article Title"},{"value":"Biochemical Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bcp.2017.09.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}