{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T19:21:23Z","timestamp":1789154483682,"version":"build-2803163510"},"reference-count":305,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,3,1]],"date-time":"2018-03-01T00:00:00Z","timestamp":1519862400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,3,1]],"date-time":"2018-03-01T00:00:00Z","timestamp":1519862400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2019,3,19]],"date-time":"2019-03-19T00:00:00Z","timestamp":1552953600000},"content-version":"am","delay-in-days":383,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100005851","name":"Shahid Beheshti University of Medical Sciences","doi-asserted-by":"publisher","award":["1396\/D\/93065"],"award-info":[{"award-number":["1396\/D\/93065"]}],"id":[{"id":"10.13039\/501100005851","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01GM123508"],"award-info":[{"award-number":["R01GM123508"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R24 DA018055"],"award-info":[{"award-number":["R24 DA018055"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical Pharmacology"],"published-print":{"date-parts":[[2018,3]]},"DOI":"10.1016\/j.bcp.2018.01.017","type":"journal-article","created":{"date-parts":[[2018,1,9]],"date-time":"2018-01-09T15:06:03Z","timestamp":1515510363000},"page":"42-59","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":109,"special_numbering":"C","title":["Regulation of vascular tone homeostasis by NO and H2S: Implications in hypertension"],"prefix":"10.1016","volume":"149","author":[{"given":"Sevda","family":"Gheibi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sajad","family":"Jeddi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khosrow","family":"Kashfi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asghar","family":"Ghasemi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bcp.2018.01.017_b0005","doi-asserted-by":"crossref","first-page":"1416","DOI":"10.2174\/138920111798281117","article-title":"Hydrogen sulfide regulates intracellular Ca2+ concentration in endothelial cells from excised rat aorta","volume":"12","author":"Moccia","year":"2011","journal-title":"Curr. Pharm. Biotechnol."},{"key":"10.1016\/j.bcp.2018.01.017_b0010","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1007\/s00726-004-0072-x","article-title":"Endogenous production of hydrogen sulfide in mammals","volume":"26","author":"Kamoun","year":"2004","journal-title":"Amino Acids"},{"key":"10.1016\/j.bcp.2018.01.017_b0015","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.phrs.2012.12.005","article-title":"Vasorelaxation by hydrogen sulphide involves activation of Kv7 potassium channels","volume":"70","author":"Martelli","year":"2013","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.bcp.2018.01.017_b0020","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.tox.2007.08.087","article-title":"Hydrogen sulfide inhibits activity of three isoforms of recombinant nitric oxide synthase","volume":"241","author":"Kubo","year":"2007","journal-title":"Toxicology"},{"key":"10.1016\/j.bcp.2018.01.017_b0025","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1161\/HYPERTENSIONAHA.116.08964","article-title":"Impaired hydrogen sulfide-mediated vasodilation contributes to microvascular endothelial dysfunction in hypertensive adults","volume":"69","author":"Greaney","year":"2017","journal-title":"Hypertension"},{"key":"10.1016\/j.bcp.2018.01.017_b0030","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1007\/s12031-014-0284-9","article-title":"Hydrogen sulfide protects the brain against ischemic reperfusion injury in a transient model of focal cerebral ischemia","volume":"54","author":"Gheibi","year":"2014","journal-title":"J. Mol. Neurosci."},{"key":"10.1016\/j.bcp.2018.01.017_b0035","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1097\/FJC.0b013e31820eb7a1","article-title":"Hydrogen sulfide: a novel signaling molecule in the vascular system","volume":"58","author":"Liu","year":"2011","journal-title":"J. Cardiovasc. Pharmacol."},{"key":"10.1016\/j.bcp.2018.01.017_b0040","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1126\/science.1162667","article-title":"H2S as a physiologic vasorelaxant: hypertension in mice with deletion of cystathionine gamma-lyase","volume":"322","author":"Yang","year":"2008","journal-title":"Science"},{"key":"10.1016\/j.bcp.2018.01.017_b0045","doi-asserted-by":"crossref","first-page":"6008","DOI":"10.1093\/emboj\/20.21.6008","article-title":"The vasorelaxant effect of H(2)S as a novel endogenous gaseous K(ATP) channel opener","volume":"20","author":"Zhao","year":"2001","journal-title":"EMBO J."},{"key":"10.1016\/j.bcp.2018.01.017_b0050","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1038\/sj.bjp.0706906","article-title":"Regulation of vascular nitric oxide in vitro and in vivo; a new role for endogenous hydrogen sulphide?","volume":"149","author":"Ali","year":"2006","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.bcp.2018.01.017_b0055","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1007\/s00726-010-0510-x","article-title":"Hydrogen sulfide: its production, release and functions","volume":"41","author":"Kimura","year":"2011","journal-title":"Amino Acids"},{"key":"10.1016\/j.bcp.2018.01.017_b0060","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1146\/annurev-pharmtox-010510-100505","article-title":"Hydrogen sulfide and cell signaling","volume":"51","author":"Li","year":"2011","journal-title":"Annu. Rev. Pharmacol. Toxicol."},{"key":"10.1016\/j.bcp.2018.01.017_b0065","doi-asserted-by":"crossref","first-page":"C3","DOI":"10.1152\/ajpcell.00282.2016","article-title":"Hydrogen sulfide, an enhancer of vascular nitric oxide signaling: mechanisms and implications","volume":"312","author":"Szabo","year":"2017","journal-title":"Am. J. Physiol. Cell physiol."},{"key":"10.1016\/j.bcp.2018.01.017_b0070","doi-asserted-by":"crossref","first-page":"59ps4","DOI":"10.1126\/scitranslmed.3000721","article-title":"Gaseotransmitters: new frontiers for translational science","volume":"2","author":"Szabo","year":"2010","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.bcp.2018.01.017_b0075","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1080\/14728222.2017.1310840","article-title":"The potential of stimulating nitric oxide formation in the treatment of hypertension","volume":"21","author":"Pinheiro","year":"2017","journal-title":"Expert Opin. Ther. Targets"},{"key":"10.1016\/j.bcp.2018.01.017_b0080","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/S0140-6736(05)17741-1","article-title":"Global burden of hypertension: analysis of worldwide data","volume":"365","author":"Kearney","year":"2005","journal-title":"Lancet"},{"key":"10.1016\/j.bcp.2018.01.017_b0085","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1038\/hr.2012.138","article-title":"Endothelial dysfunction and hypertension in aging","volume":"35","author":"Higashi","year":"2012","journal-title":"Hypertens. Res."},{"key":"10.1016\/j.bcp.2018.01.017_b0090","doi-asserted-by":"crossref","first-page":"302","DOI":"10.2174\/1874192401004010302","article-title":"The endothelium and its role in regulating vascular tone","volume":"4","author":"Sandoo","year":"2010","journal-title":"Open Cardiovasc. Med. J."},{"key":"10.1016\/j.bcp.2018.01.017_b0095","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1097\/MNH.0000000000000206","article-title":"Hydrogen sulfide in hypertension","volume":"25","author":"van Goor","year":"2016","journal-title":"Curr. Opin. Nephrol. Hypertens."},{"key":"10.1016\/j.bcp.2018.01.017_b0100","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1089\/ars.2007.1989","article-title":"Nitric oxide, tetrahydrobiopterin, oxidative stress, and endothelial dysfunction in hypertension","volume":"10","author":"Schulz","year":"2008","journal-title":"Antioxid. Redox Signaling"},{"key":"10.1016\/j.bcp.2018.01.017_b0105","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1016\/j.tips.2015.05.007","article-title":"The role of H2S bioavailability in endothelial dysfunction","volume":"36","author":"Wang","year":"2015","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.bcp.2018.01.017_b0110","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1038\/333664a0","article-title":"Vascular endothelial cells synthesize nitric oxide from L-arginine","volume":"333","author":"Palmer","year":"1988","journal-title":"Nature"},{"key":"10.1016\/j.bcp.2018.01.017_b0115","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1111\/j.1524-6175.2006.06032.x","article-title":"Nitric oxide in hypertension","volume":"8","author":"Hermann","year":"2006","journal-title":"J. Clin. Hypertens."},{"key":"10.1016\/j.bcp.2018.01.017_b0120","doi-asserted-by":"crossref","first-page":"2112","DOI":"10.1046\/j.1538-7836.2003.00345.x","article-title":"Nitric oxide in vascular biology","volume":"1","author":"Walford","year":"2003","journal-title":"J. Thrombosis Haemostasis"},{"key":"10.1016\/j.bcp.2018.01.017_b0125","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1096\/fasebj.3.1.2642868","article-title":"Endothelium-derived nitric oxide: actions and properties","volume":"3","author":"Ignarro","year":"1989","journal-title":"FASEB J."},{"key":"10.1016\/j.bcp.2018.01.017_b0130","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1161\/01.HYP.25.6.1202","article-title":"Nitric oxide and its putative role in hypertension","volume":"25","author":"Dominiczak","year":"1995","journal-title":"Hypertension"},{"key":"10.1016\/j.bcp.2018.01.017_b0135","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.1097\/HJH.0000000000000587","article-title":"Mechanisms and consequences of endothelial nitric oxide synthase dysfunction in hypertension","volume":"33","author":"Li","year":"2015","journal-title":"J. Hypertens."},{"key":"10.1016\/j.bcp.2018.01.017_b0140","article-title":"Phenotypic consequences of a genetic predisposition to enhanced nitric oxide signaling","author":"Emdin","year":"2017","journal-title":"Circulation"},{"issue":"Suppl. 1","key":"10.1016\/j.bcp.2018.01.017_b0145","doi-asserted-by":"crossref","first-page":"S21","DOI":"10.1038\/sj.jhh.1001889","article-title":"Targeting endothelial dysfunction in hypertensive subjects","volume":"19","author":"Thuillez","year":"2005","journal-title":"J. Hum. Hypertens."},{"key":"10.1016\/j.bcp.2018.01.017_b0150","doi-asserted-by":"crossref","first-page":"1613","DOI":"10.1182\/blood-2010-01-267112","article-title":"The critical roles of platelet activation and reduced NO bioavailability in fatal pulmonary arterial hypertension in a murine hemolysis model","volume":"116","author":"Hu","year":"2010","journal-title":"Blood"},{"key":"10.1016\/j.bcp.2018.01.017_b0155","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1038\/nrd2466","article-title":"The nitrate\u2013nitrite\u2013nitric oxide pathway in physiology and therapeutics","volume":"7","author":"Lundberg","year":"2008","journal-title":"Nat. Rev. Drug Discovery"},{"key":"10.1016\/j.bcp.2018.01.017_b0160","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.freeradbiomed.2013.01.024","article-title":"Effect of dietary nitrate on blood pressure, endothelial function, and insulin sensitivity in type 2 diabetes","volume":"60","author":"Gilchrist","year":"2013","journal-title":"Free Radical Biol. Med."},{"key":"10.1016\/j.bcp.2018.01.017_b0165","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1161\/HYPERTENSIONAHA.114.04675","article-title":"Dietary nitrate provides sustained blood pressure lowering in hypertensive patients: a randomized, phase 2, double-blind, placebo-controlled study","volume":"65","author":"Kapil","year":"2015","journal-title":"Hypertension"},{"key":"10.1016\/j.bcp.2018.01.017_b0170","doi-asserted-by":"crossref","first-page":"H2163","DOI":"10.1152\/ajpheart.00525.2004","article-title":"Nitrite is an alternative source of NO in vivo","volume":"288","author":"Tsuchiya","year":"2005","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.bcp.2018.01.017_b0175","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.freeradbiomed.2011.04.005","article-title":"Sodium nitrite downregulates vascular NADPH oxidase and exerts antihypertensive effects in hypertension","volume":"51","author":"Montenegro","year":"2011","journal-title":"Free Radical Biol. Med."},{"key":"10.1016\/j.bcp.2018.01.017_b0180","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1080\/07315724.1990.10720407","article-title":"Hypothesis: the effect of oral nitrite on blood pressure in the spontaneously hypertensive rat. Does dietary nitrate mitigate hypertension after conversion to nitrite?","volume":"9","author":"Classen","year":"1990","journal-title":"J. Am. Coll. Nutr."},{"key":"10.1016\/j.bcp.2018.01.017_b0185","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/j.redox.2015.06.009","article-title":"Consistent antioxidant and antihypertensive effects of oral sodium nitrite in DOCA-salt hypertension","volume":"5","author":"Amaral","year":"2015","journal-title":"Redox. Biol."},{"key":"10.1016\/j.bcp.2018.01.017_b0190","doi-asserted-by":"crossref","DOI":"10.1161\/HYPERTENSIONAHA.107.103523","article-title":"Acute blood pressure lowering, vasoprotective, and antiplatelet properties of dietary nitrate via bioconversion to nitrite","volume":"51","author":"Webb","year":"2008","journal-title":"Hypertension"},{"key":"10.1016\/j.bcp.2018.01.017_b0195","doi-asserted-by":"crossref","DOI":"10.1152\/ajpregu.00206.2010","article-title":"Acute and chronic effects of dietary nitrate supplementation on blood pressure and the physiological responses to moderate-intensity and incremental exercise","volume":"299","author":"Vanhatalo","year":"2010","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.bcp.2018.01.017_b0200","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1186\/1475-2891-11-106","article-title":"Effect of beetroot juice on lowering blood pressure in free-living, disease-free adults: a randomized, placebo-controlled trial","volume":"11","author":"Coles","year":"2012","journal-title":"Nutr. J."},{"key":"10.1016\/j.bcp.2018.01.017_b0205","article-title":"Blood pressure-lowering effects of beetroot juice and novel beetroot-enriched breads in normotensive male subjects","volume":"14","author":"Hobbs","year":"2012","journal-title":"Br. J. Nutr."},{"key":"10.1016\/j.bcp.2018.01.017_b0210","doi-asserted-by":"crossref","DOI":"10.3945\/jn.112.170233","article-title":"Inorganic nitrate and beetroot juice supplementation reduces blood pressure in adults: a systematic review and meta-analysis","volume":"143","author":"Siervo","year":"2013","journal-title":"J. Nutr."},{"key":"10.1016\/j.bcp.2018.01.017_b0215","doi-asserted-by":"crossref","first-page":"830","DOI":"10.3945\/an.117.016717","article-title":"Nitrate-independent blood pressure lowering effect of beetroot juice: A systematic review and meta-analysis","volume":"8","author":"Bahadoran","year":"2017","journal-title":"Adv. Nutr."},{"key":"10.1016\/j.bcp.2018.01.017_b0220","doi-asserted-by":"crossref","DOI":"10.3390\/nu8120811","article-title":"Association between dietary intakes of nitrate and nitrite and the risk of hypertension and chronic kidney disease: Tehran lipid and glucose study","volume":"8","author":"Bahadoran","year":"2016","journal-title":"Nutrients"},{"key":"10.1016\/j.bcp.2018.01.017_b0225","first-page":"1","article-title":"Consumption of nitrate containing vegetables and the risk of chronic kidney disease: Tehran Lipid and Glucose Study","author":"Mirmiran","year":"2016","journal-title":"Renal failure"},{"key":"10.1016\/j.bcp.2018.01.017_b0230","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.freeradbiomed.2016.07.025","article-title":"Dietary nitrate improves age-related hypertension and metabolic abnormalities in rats via modulation of angiotensin II receptor signaling and inhibition of superoxide generation","volume":"99","author":"Hezel","year":"2016","journal-title":"Free Radical Biol. Med."},{"key":"10.1016\/j.bcp.2018.01.017_b0235","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.bbrc.2003.11.081","article-title":"The possible role of hydrogen sulfide on the pathogenesis of spontaneous hypertension in rats","volume":"313","author":"Yan","year":"2004","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bcp.2018.01.017_b0240","doi-asserted-by":"crossref","first-page":"243","DOI":"10.4103\/0253-7613.157106","article-title":"A critical review of pharmacological significance of Hydrogen Sulfide in hypertension","volume":"47","author":"Ahmad","year":"2015","journal-title":"Indian J. Pharmacol."},{"key":"10.1016\/j.bcp.2018.01.017_b0245","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1097\/00029330-200703010-00008","article-title":"Imbalance of endogenous homocysteine and hydrogen sulfide metabolic pathway in essential hypertensive children","volume":"120","author":"Chen","year":"2007","journal-title":"Chin. Med. J."},{"key":"10.1016\/j.bcp.2018.01.017_b0250","doi-asserted-by":"crossref","first-page":"503","DOI":"10.2119\/molmed.2013.00096","article-title":"Hydrogen sulfide alleviates myocardial collagen remodeling in association with inhibition of TGF-beta\/Smad signaling pathway in spontaneously hypertensive rats","volume":"20","author":"Sun","year":"2015","journal-title":"Mol. Med."},{"key":"10.1016\/j.bcp.2018.01.017_b0255","doi-asserted-by":"crossref","first-page":"1619","DOI":"10.1291\/hypres.31.1619","article-title":"Regulatory effect of hydrogen sulfide on vascular collagen content in spontaneously hypertensive rats","volume":"31","author":"Zhao","year":"2008","journal-title":"Hypertens. Res."},{"key":"10.1016\/j.bcp.2018.01.017_b0260","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.niox.2015.01.004","article-title":"Down-regulated CBS\/H2S pathway is involved in high-salt-induced hypertension in Dahl rats","volume":"46","author":"Huang","year":"2015","journal-title":"Nitric Oxide"},{"key":"10.1016\/j.bcp.2018.01.017_b0265","doi-asserted-by":"crossref","first-page":"1879","DOI":"10.1097\/00004872-200310000-00015","article-title":"The role of hydrogen sulfide generation in the pathogenesis of hypertension in rats induced by inhibition of nitric oxide synthase","volume":"21","author":"Zhong","year":"2003","journal-title":"J. Hypertens."},{"key":"10.1016\/j.bcp.2018.01.017_b0270","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.ejphar.2012.07.022","article-title":"Novel diallyldisulfide analogs ameliorate cardiovascular remodeling in rats with L-NAME-induced hypertension","volume":"691","author":"Sharma","year":"2012","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.bcp.2018.01.017_b0275","doi-asserted-by":"crossref","first-page":"598","DOI":"10.3109\/0886022X.2014.882218","article-title":"Hydrogen sulphide and tempol treatments improve the blood pressure and renal excretory responses in spontaneously hypertensive rats","volume":"36","author":"Ahmad","year":"2014","journal-title":"Renal Failure"},{"key":"10.1016\/j.bcp.2018.01.017_b0280","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/1475-2891-1-4","article-title":"Effect of garlic on cardiovascular disorders: a review","volume":"1","author":"Banerjee","year":"2002","journal-title":"Nutr. J."},{"key":"10.1016\/j.bcp.2018.01.017_b0285","doi-asserted-by":"crossref","first-page":"17977","DOI":"10.1073\/pnas.0705710104","article-title":"Hydrogen sulfide mediates the vasoactivity of garlic","volume":"104","author":"Benavides","year":"2007","journal-title":"PNAS"},{"key":"10.1016\/j.bcp.2018.01.017_b0290","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.jep.2003.06.001","article-title":"Endothelium mediated vasorelaxant response of garlic in isolated rat aorta: role of nitric oxide","volume":"90","author":"Ashraf","year":"2004","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.bcp.2018.01.017_b0295","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.niox.2014.11.010","article-title":"H2S-releasing drugs: anti-inflammatory, cytoprotective and chemopreventative potential","volume":"46","author":"Gemici","year":"2015","journal-title":"Nitric Oxide"},{"key":"10.1016\/j.bcp.2018.01.017_b0300","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/j.bbrc.2012.02.051","article-title":"NOSH-aspirin (NBS-1120), a novel nitric oxide- and hydrogen sulfide-releasing hybrid is a potent inhibitor of colon cancer cell growth in vitro and in a xenograft mouse model","volume":"419","author":"Chattopadhyay","year":"2012","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bcp.2018.01.017_b0305","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1089\/ars.2013.5308","article-title":"Anti-cancer activity of new designer hydrogen sulfide-donating hybrids","volume":"20","author":"Kashfi","year":"2014","journal-title":"Antioxid. Redox Signaling"},{"key":"10.1016\/j.bcp.2018.01.017_b0310","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1089\/ars.2011.4349","article-title":"Role of cystathionine gamma-lyase\/hydrogen sulfide pathway in cardiovascular disease: a novel therapeutic strategy?","volume":"17","author":"Pan","year":"2012","journal-title":"Antioxid. Redox Signaling"},{"key":"10.1016\/j.bcp.2018.01.017_b0315","series-title":"Chemistry Biochemistry and Pharmacology of Hydrogen Sulfide","author":"Moore","year":"2015"},{"key":"10.1016\/j.bcp.2018.01.017_b0320","doi-asserted-by":"crossref","DOI":"10.1152\/ajpcell.00329.2016","article-title":"Vascular biology of hydrogen sulfide","author":"Kanagy","year":"2017","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"10.1016\/j.bcp.2018.01.017_b0325","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1016\/j.bcp.2012.10.019","article-title":"Biology and therapeutic potential of hydrogen sulfide and hydrogen sulfide-releasing chimeras","volume":"85","author":"Kashfi","year":"2013","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.bcp.2018.01.017_b0330","first-page":"187","article-title":"Purification and characterization of cysteine aminotransferase from rat liver cytosol","volume":"36","author":"Akagi","year":"1982","journal-title":"Acta Med. Okayama"},{"key":"10.1016\/j.bcp.2018.01.017_b0335","first-page":"483","article-title":"Purification and characterization of mitochondrial cysteine aminotransferase from rat liver","volume":"10","author":"Ubuka","year":"1978","journal-title":"Physiol. Chem. Phys."},{"key":"10.1016\/j.bcp.2018.01.017_b0340","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1097\/MNH.0b013e3283430651","article-title":"Signaling pathways for the vascular effects of hydrogen sulfide","volume":"20","author":"Wang","year":"2011","journal-title":"Curr. Opin. Nephrol. Hypertens."},{"key":"10.1016\/j.bcp.2018.01.017_b0345","doi-asserted-by":"crossref","first-page":"1439","DOI":"10.1161\/CIRCRESAHA.110.228999","article-title":"Intermittent hypoxia in rats increases myogenic tone through loss of hydrogen sulfide activation of large-conductance Ca(2+)-activated potassium channels","volume":"108","author":"Jackson-Weaver","year":"2011","journal-title":"Circulation Res."},{"key":"10.1016\/j.bcp.2018.01.017_b0350","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1089\/ars.2011.4359","article-title":"Modulation of ion channels by hydrogen sulfide","volume":"17","author":"Peers","year":"2012","journal-title":"Antioxid. Redox Signaling"},{"key":"10.1016\/j.bcp.2018.01.017_b0355","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1007\/s10517-012-1886-2","article-title":"Distribution of H2S synthesis enzymes in the walls of cerebral arteries in rats","volume":"154","author":"Chertok","year":"2012","journal-title":"Bull. Exp. Biol. Med."},{"key":"10.1016\/j.bcp.2018.01.017_b0360","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.niox.2013.07.002","article-title":"Hydrogen sulfide chemical biology: pathophysiological roles and detection","volume":"35","author":"Kolluru","year":"2013","journal-title":"Nitric Oxide"},{"key":"10.1016\/j.bcp.2018.01.017_b0365","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.ab.2005.03.024","article-title":"Polarographic measurement of hydrogen sulfide production and consumption by mammalian tissues","volume":"341","author":"Doeller","year":"2005","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.bcp.2018.01.017_b0370","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1161\/01.RES.73.5.808","article-title":"Negative feedback regulation of endothelial cell function by nitric oxide","volume":"73","author":"Buga","year":"1993","journal-title":"Circulation Res."},{"key":"10.1016\/j.bcp.2018.01.017_b0375","doi-asserted-by":"crossref","first-page":"6876","DOI":"10.1021\/bi010066m","article-title":"Regulation of inducible nitric oxide synthase by self-generated NO","volume":"40","author":"Abu-Soud","year":"2001","journal-title":"Biochemistry"},{"key":"10.1016\/j.bcp.2018.01.017_b0380","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.1093\/jn\/106.9.1272","article-title":"Fractors affecting the rate of gluconeogenesis from L-cysteine in the perfused rat liver","volume":"106","author":"Simpson","year":"1976","journal-title":"J. Nutr."},{"key":"10.1016\/j.bcp.2018.01.017_b0385","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1111\/j.1745-7254.2008.00845.x","article-title":"Endogenously generated sulfur dioxide and its vasorelaxant effect in rats","volume":"29","author":"Du","year":"2008","journal-title":"Acta Pharmacol. Sin."},{"key":"10.1016\/j.bcp.2018.01.017_b0390","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1093\/jb\/mvp111","article-title":"Vascular endothelium expresses 3-mercaptopyruvate sulfurtransferase and produces hydrogen sulfide","volume":"146","author":"Shibuya","year":"2009","journal-title":"J. Biochem."},{"key":"10.1016\/j.bcp.2018.01.017_b0395","doi-asserted-by":"crossref","first-page":"2174","DOI":"10.1097\/HJH.0b013e328330a900","article-title":"Hydrogen sulfide derived from periadventitial adipose tissue is a vasodilator","volume":"27","author":"Fang","year":"2009","journal-title":"J. Hypertens."},{"key":"10.1016\/j.bcp.2018.01.017_b0400","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1139\/cjpp-2013-0001","article-title":"Endogenous hydrogen sulfide in perivascular adipose tissue: role in the regulation of vascular tone in physiology and pathology","volume":"91","author":"Beltowski","year":"2013","journal-title":"Can. J. Physiol. Pharmacol."},{"key":"10.1016\/j.bcp.2018.01.017_b0405","doi-asserted-by":"crossref","first-page":"e41951","DOI":"10.1371\/journal.pone.0041951","article-title":"Differential effects of cystathionine-gamma-lyase-dependent vasodilatory H2S in periadventitial vasoregulation of rat and mouse aortas","volume":"7","author":"Kohn","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.bcp.2018.01.017_b0410","doi-asserted-by":"crossref","first-page":"4747","DOI":"10.1113\/JP271006","article-title":"Perivascular tissue inhibits rho-kinase-dependent smooth muscle Ca(2+) sensitivity and endothelium-dependent H2 S signalling in rat coronary arteries","volume":"593","author":"Aalbaek","year":"2015","journal-title":"J. Physiol."},{"key":"10.1016\/j.bcp.2018.01.017_b0415","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1161\/CIRCRESAHA.111.240242","article-title":"Hydrogen sulfide as endothelium-derived hyperpolarizing factor sulfhydrates potassium channels","volume":"109","author":"Mustafa","year":"2011","journal-title":"Circulation Res."},{"key":"10.1016\/j.bcp.2018.01.017_b0420","doi-asserted-by":"crossref","first-page":"H474","DOI":"10.1152\/ajpheart.00013.2002","article-title":"H(2)S-induced vasorelaxation and underlying cellular and molecular mechanisms","volume":"283","author":"Zhao","year":"2002","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.bcp.2018.01.017_b0425","first-page":"1","article-title":"Serum nitric oxide metabolite levels in groups of patients with various diseases in comparison of healthy control subjects","volume":"10","author":"Higashino","year":"2010","journal-title":"J. Med. Sci."},{"key":"10.1016\/j.bcp.2018.01.017_b0430","first-page":"59","article-title":"Is nitric oxide a hormone?","volume":"15","author":"Ghasemi","year":"2011","journal-title":"Iran. Biomed. J."},{"key":"10.1016\/j.bcp.2018.01.017_b0435","doi-asserted-by":"crossref","first-page":"E1177","DOI":"10.1152\/ajpendo.00284.2012","article-title":"Arginine de novo and nitric oxide production in disease states","volume":"303","author":"Luiking","year":"2012","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"10.1016\/j.bcp.2018.01.017_b0440","doi-asserted-by":"crossref","first-page":"2237","DOI":"10.2741\/4047","article-title":"Regulatory roles for L-arginine in reducing white adipose tissue","volume":"17","author":"Tan","year":"2012","journal-title":"Front. Biosci."},{"key":"10.1016\/j.bcp.2018.01.017_b0445","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.niox.2017.08.003","article-title":"Anti-obesity and anti-diabetic effects of nitrate and nitrite","volume":"70","author":"Ghasemi","year":"2017","journal-title":"Nitric Oxide"},{"key":"10.1016\/j.bcp.2018.01.017_b0450","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1111\/j.1749-6632.1995.tb17477.x","article-title":"S-nitrosylation of m2 muscarinic receptor thiols disrupts receptor-G-protein coupling","volume":"757","author":"Aronstam","year":"1995","journal-title":"Ann. N. Y. Acad. Sci."},{"issue":"Pt. 2","key":"10.1016\/j.bcp.2018.01.017_b0455","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1042\/bj2980249","article-title":"Nitric oxide synthases in mammals","volume":"298","author":"Knowles","year":"1994","journal-title":"Biochem. J."},{"key":"10.1016\/j.bcp.2018.01.017_b0460","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/S0014-5793(97)01397-5","article-title":"Nitric oxide synthase activity in mitochondria","volume":"418","author":"Ghafourifar","year":"1997","journal-title":"FEBS Lett."},{"key":"10.1016\/j.bcp.2018.01.017_b0465","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.niox.2005.05.011","article-title":"Mitochondrial NO and reactive nitrogen species production: does mtNOS exist?","volume":"14","author":"Lacza","year":"2006","journal-title":"Nitric Oxide"},{"key":"10.1016\/j.bcp.2018.01.017_b0470","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1093\/eurheartj\/ehr304","article-title":"Nitric oxide synthases: regulation and function","volume":"33","author":"Forstermann","year":"2012","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.bcp.2018.01.017_b0475","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.niox.2017.01.003","article-title":"Nitrite increases glucose-stimulated insulin secretion and islet insulin content in obese type 2 diabetic male rats","volume":"64","author":"Gheibi","year":"2017","journal-title":"Nitric Oxide"},{"key":"10.1016\/j.bcp.2018.01.017_b0480","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.niox.2016.02.004","article-title":"Added value of total serum nitrate\/nitrite for prediction of cardiovascular disease in middle east caucasian residents in Tehran","volume":"54","author":"Hadaegh","year":"2016","journal-title":"Nitric Oxide"},{"key":"10.1016\/j.bcp.2018.01.017_b0485","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1111\/joim.12441","article-title":"Therapeutic effects of inorganic nitrate and nitrite in cardiovascular and metabolic diseases","volume":"279","author":"Omar","year":"2016","journal-title":"J. Intern. Med."},{"key":"10.1016\/j.bcp.2018.01.017_b0490","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1096\/fj.01-0842com","article-title":"Vascular smooth muscle and nitric oxide synthase","volume":"16","author":"Buchwalow","year":"2002","journal-title":"FASEB J."},{"key":"10.1016\/j.bcp.2018.01.017_b0495","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1002\/biof.3","article-title":"Nitric oxide and vascular insulin resistance","volume":"35","author":"Wu","year":"2009","journal-title":"Biofactors"},{"key":"10.1016\/j.bcp.2018.01.017_b0500","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1016\/0024-3205(93)90063-9","article-title":"Vascular smooth muscle and nitric oxide","volume":"52","author":"Zehetgruber","year":"1993","journal-title":"Life Sci."},{"key":"10.1016\/j.bcp.2018.01.017_b0505","doi-asserted-by":"crossref","first-page":"H991","DOI":"10.1152\/ajpheart.2000.278.3.H991","article-title":"Functional expression of NOS 1 in vascular smooth muscle","volume":"278","author":"Brophy","year":"2000","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.bcp.2018.01.017_b0510","doi-asserted-by":"crossref","first-page":"2584","DOI":"10.1161\/01.ATV.19.11.2584","article-title":"Potential functional significance of brain-type and muscle-type nitric oxide synthase I expressed in adventitia and media of rat aorta","volume":"19","author":"Schwarz","year":"1999","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.bcp.2018.01.017_b0515","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.jphs.2015.09.002","article-title":"Vascular nitric oxide: Beyond eNOS","volume":"129","author":"Zhao","year":"2015","journal-title":"J. Pharmacol. Sci."},{"key":"10.1016\/j.bcp.2018.01.017_b0520","doi-asserted-by":"crossref","first-page":"4229","DOI":"10.1182\/blood-2012-07-442277","article-title":"Human red blood cells at work: identification and visualization of erythrocytic eNOS activity in health and disease","volume":"120","author":"Cortese-Krott","year":"2012","journal-title":"Blood"},{"key":"10.1016\/j.bcp.2018.01.017_b0525","doi-asserted-by":"crossref","first-page":"65","DOI":"10.2174\/1568006053005047","article-title":"Nitric oxide and its antithrombotic action in the cardiovascular system","volume":"5","author":"Reichenbach","year":"2005","journal-title":"Curr. Drug Targets Cardiovasc. Haematol. Disord."},{"key":"10.1016\/j.bcp.2018.01.017_b0530","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1016\/S0895-7061(00)01297-8","article-title":"Decreased nitric oxide levels and increased calcium content in platelets of hypertensive patients","volume":"14","author":"Camilletti","year":"2001","journal-title":"Am. J. Hypertens."},{"key":"10.1016\/j.bcp.2018.01.017_b0535","doi-asserted-by":"crossref","DOI":"10.1161\/ATVBAHA.112.301068","article-title":"Circulating blood eNOS contributes to the regulation of systemic blood pressure and nitrite homeostasis","volume":"33","author":"Wood","year":"2013","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.bcp.2018.01.017_b0540","doi-asserted-by":"crossref","first-page":"8310","DOI":"10.1074\/jbc.M115.639831","article-title":"Sulfide oxidation by a noncanonical pathway in red blood cells generates thiosulfate and polysulfides","volume":"290","author":"Vitvitsky","year":"2015","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bcp.2018.01.017_b0545","doi-asserted-by":"crossref","first-page":"8476","DOI":"10.1021\/jacs.6b03456","article-title":"Hydrogen sulfide oxidation by myoglobin","volume":"138","author":"Bostelaar","year":"2016","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.bcp.2018.01.017_b0550","doi-asserted-by":"crossref","first-page":"17716","DOI":"10.1073\/pnas.1008872107","article-title":"Dietary inorganic nitrate reverses features of metabolic syndrome in endothelial nitric oxide synthase-deficient mice","volume":"107","author":"Carlstrom","year":"2010","journal-title":"PNAS"},{"issue":"Pt. 1","key":"10.1016\/j.bcp.2018.01.017_b0555","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1042\/bj3300527","article-title":"Estimation of total rate of formation of nitric oxide in the rat","volume":"330","author":"Sakinis","year":"1998","journal-title":"Biochem. J."},{"key":"10.1016\/j.bcp.2018.01.017_b0560","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.niox.2003.09.001","article-title":"A technique to estimate the rate of whole body nitric oxide formation in conscious mice","volume":"9","author":"Wickman","year":"2003","journal-title":"Nitric Oxide"},{"key":"10.1016\/j.bcp.2018.01.017_b0565","first-page":"1921","article-title":"Metabolic fate of an oral dose of 15N-labeled nitrate in humans: effect of diet supplementation with ascorbic acid","volume":"43","author":"Wagner","year":"1983","journal-title":"Cancer Res."},{"key":"10.1016\/j.bcp.2018.01.017_b0570","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/S0005-2728(99)00020-1","article-title":"Nitric oxide metabolism and breakdown","volume":"1411","author":"Kelm","year":"1999","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bcp.2018.01.017_b0575","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1002\/clc.4960200412","article-title":"Plasma nitrite\/nitrate level is inversely correlated with plasma low-density lipoprotein cholesterol level","volume":"20","author":"Tanaka","year":"1997","journal-title":"Clin. Cardiol."},{"key":"10.1016\/j.bcp.2018.01.017_b0580","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1002\/j.2040-4603.2017.tb00747.x","article-title":"Smooth muscle ion channels and regulation of vascular tone in resistance arteries and arterioles","volume":"7","author":"Tykocki","year":"2017","journal-title":"Compr. Physiol."},{"key":"10.1016\/j.bcp.2018.01.017_b0585","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1038\/nature04711","article-title":"KATP channels as molecular sensors of cellular metabolism","volume":"440","author":"Nichols","year":"2006","journal-title":"Nature"},{"key":"10.1016\/j.bcp.2018.01.017_b0590","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1161\/CIRCRESAHA.112.300514","article-title":"KATP channels and cardiovascular disease: suddenly a syndrome","volume":"112","author":"Nichols","year":"2013","journal-title":"Circulation Res."},{"key":"10.1016\/j.bcp.2018.01.017_b0595","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1124\/pr.116.012864","article-title":"International union of basic and clinical pharmacology. c. nomenclature and properties of calcium-activated and sodium-activated potassium channels","volume":"69","author":"Kaczmarek","year":"2017","journal-title":"Pharmacol. Rev."},{"key":"10.1016\/j.bcp.2018.01.017_b0600","doi-asserted-by":"crossref","first-page":"442","DOI":"10.4161\/chan.26242","article-title":"A BK (Slo1) channel journey from molecule to physiology","volume":"7","author":"Contreras","year":"2013","journal-title":"Channels"},{"key":"10.1016\/j.bcp.2018.01.017_b0605","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1161\/CIRCRESAHA.109.203620","article-title":"Smooth muscle cell alpha2delta-1 subunits are essential for vasoregulation by CaV1.2 channels","volume":"105","author":"Bannister","year":"2009","journal-title":"Circulation Res."},{"key":"10.1016\/j.bcp.2018.01.017_b0610","first-page":"135249","article-title":"Role of ryanodine receptor subtypes in initiation and formation of calcium sparks in arterial smooth muscle: comparison with striated muscle","volume":"2009","author":"Essin","year":"2009","journal-title":"J. Biomed. Biotechnol."},{"key":"10.1016\/j.bcp.2018.01.017_b0615","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1152\/physrev.00013.2002","article-title":"Ryanodine receptor calcium release channels","volume":"82","author":"Fill","year":"2002","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.bcp.2018.01.017_b0620","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.ceca.2005.06.037","article-title":"Ryanodine receptors","volume":"38","author":"Hamilton","year":"2005","journal-title":"Cell Calcium"},{"key":"10.1016\/j.bcp.2018.01.017_b0625","doi-asserted-by":"crossref","first-page":"H2190","DOI":"10.1152\/ajpheart.01146.2011","article-title":"Inositol trisphosphate receptors in smooth muscle cells","volume":"302","author":"Narayanan","year":"2012","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.bcp.2018.01.017_b0630","doi-asserted-by":"crossref","first-page":"C264","DOI":"10.1152\/ajpcell.00318.2009","article-title":"Subtype identification and functional characterization of ryanodine receptors in rat cerebral artery myocytes","volume":"299","author":"Vaithianathan","year":"2010","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"10.1016\/j.bcp.2018.01.017_b0635","doi-asserted-by":"crossref","first-page":"1849","DOI":"10.1113\/jphysiol.2011.222083","article-title":"Function and expression of ryanodine receptors and inositol 1,4,5-trisphosphate receptors in smooth muscle cells of murine feed arteries and arterioles","volume":"590","author":"Westcott","year":"2012","journal-title":"J. Physiol."},{"key":"10.1016\/j.bcp.2018.01.017_b0640","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1146\/annurev.biochem.76.053105.094237","article-title":"Modulation of the ryanodine receptor and intracellular calcium","volume":"76","author":"Zalk","year":"2007","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.bcp.2018.01.017_b0645","doi-asserted-by":"crossref","first-page":"13765","DOI":"10.1016\/S0021-9258(19)85166-9","article-title":"The ryanodine receptor\/Ca2+ release channel","volume":"268","author":"McPherson","year":"1993","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bcp.2018.01.017_b0650","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1007\/s00540-006-0487-5","article-title":"Cellular and molecular mechanisms regulating vascular tone. Part 1: basic mechanisms controlling cytosolic Ca2+ concentration and the Ca2+-dependent regulation of vascular tone","volume":"21","author":"Akata","year":"2007","journal-title":"J. Anesthesia"},{"key":"10.1016\/j.bcp.2018.01.017_b0655","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1161\/01.RES.72.2.481","article-title":"Anti-ryanodine receptor antibody binding sites in vascular and endocardial endothelium","volume":"72","author":"Lesh","year":"1993","journal-title":"Circulation Res."},{"key":"10.1016\/j.bcp.2018.01.017_b0660","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1161\/01.RES.74.1.151","article-title":"A functional ryanodine-sensitive intracellular Ca2+ store is present in vascular endothelial cells","volume":"74","author":"Ziegelstein","year":"1994","journal-title":"Circulation Res."},{"key":"10.1016\/j.bcp.2018.01.017_b0665","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1111\/j.1476-5381.1995.tb16330.x","article-title":"Caffeine-evoked, calcium-sensitive membrane currents in rabbit aortic endothelial cells","volume":"115","author":"Rusko","year":"1995","journal-title":"Br. J. Pharmacol."},{"issue":"Pt. 1","key":"10.1016\/j.bcp.2018.01.017_b0670","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1111\/j.1469-7793.1998.109bx.x","article-title":"Submaximal stimulation of porcine endothelial cells causes focal Ca2+ elevation beneath the cell membrane","volume":"506","author":"Graier","year":"1998","journal-title":"J. Physiol."},{"key":"10.1016\/j.bcp.2018.01.017_b0675","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/j.ceca.2004.04.005","article-title":"Inositol 1,4,5-trisphosphate receptor subtypes are differentially distributed between smooth muscle and endothelial layers of rat arteries","volume":"36","author":"Grayson","year":"2004","journal-title":"Cell Calcium"},{"key":"10.1016\/j.bcp.2018.01.017_b0680","doi-asserted-by":"crossref","first-page":"707","DOI":"10.3389\/fimmu.2017.00707","article-title":"The role of transient receptor potential channel 6 channels in the pulmonary vasculature","volume":"8","author":"Malczyk","year":"2017","journal-title":"Front. Immunol."},{"key":"10.1016\/j.bcp.2018.01.017_b0685","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1016\/j.bbadis.2007.02.013","article-title":"TRP channels in endothelial function and dysfunction","volume":"1772","author":"Kwan","year":"2007","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bcp.2018.01.017_b0690","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1152\/physrev.00026.2014","article-title":"Transient receptor potential channels in the vasculature","volume":"95","author":"Earley","year":"2015","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.bcp.2018.01.017_b0695","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1161\/01.RES.0000194321.60300.d6","article-title":"TRPV4 forms a novel Ca2+ signaling complex with ryanodine receptors and BKCa channels","volume":"97","author":"Earley","year":"2005","journal-title":"Circulation Res."},{"key":"10.1016\/j.bcp.2018.01.017_b0700","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/S0008-6363(01)00281-4","article-title":"Expression of ryanodine receptor type 3 and TRP channels in endothelial cells: comparison of in situ and cultured human endothelial cells","volume":"51","author":"Kohler","year":"2001","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.bcp.2018.01.017_b0705","doi-asserted-by":"crossref","DOI":"10.3390\/ijms18051024","article-title":"Calcium dynamics mediated by the endoplasmic\/sarcoplasmic reticulum and related diseases","volume":"18","author":"Reddish","year":"2017","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.bcp.2018.01.017_b0710","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/S0165-6147(00)01596-0","article-title":"Rho-Rho-kinase pathway in smooth muscle contraction and cytoskeletal reorganization of non-muscle cells","volume":"22","author":"Fukata","year":"2001","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.bcp.2018.01.017_b0715","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.abb.2011.05.008","article-title":"Intracellular regulation of heterotrimeric G-protein signaling modulates vascular smooth muscle cell contraction","volume":"510","author":"Bastin","year":"2011","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.bcp.2018.01.017_b0720","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1161\/01.RES.84.2.210","article-title":"Mechanism of nitric oxide-induced vasodilatation: refilling of intracellular stores by sarcoplasmic reticulum Ca2+ ATPase and inhibition of store-operated Ca2+ influx","volume":"84","author":"Cohen","year":"1999","journal-title":"Circulation Res."},{"key":"10.1016\/j.bcp.2018.01.017_b0725","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/S0022-2828(03)00045-2","article-title":"Regulation of force in vascular smooth muscle","volume":"35","author":"Ogut","year":"2003","journal-title":"J. Mol. Cell. Cardiol."},{"key":"10.1016\/j.bcp.2018.01.017_b0730","first-page":"201","article-title":"Pharmacomechanical coupling: the role of calcium, G-proteins, kinases and phosphatases","volume":"134","author":"Somlyo","year":"1999","journal-title":"Rev. Physiol. Biochem. Pharmacol."},{"key":"10.1016\/j.bcp.2018.01.017_b0735","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1152\/physrev.00023.2003","article-title":"Ca2+ sensitivity of smooth muscle and nonmuscle myosin II: modulated by G proteins, kinases, and myosin phosphatase","volume":"83","author":"Somlyo","year":"2003","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.bcp.2018.01.017_b0740","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1124\/pr.110.002907","article-title":"cGMP-dependent protein kinases and cGMP phosphodiesterases in nitric oxide and cGMP action","volume":"62","author":"Francis","year":"2010","journal-title":"Pharmacol. Rev."},{"key":"10.1016\/j.bcp.2018.01.017_b0745","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1006\/bbrc.1997.6878","article-title":"The possible role of hydrogen sulfide as an endogenous smooth muscle relaxant in synergy with nitric oxide","volume":"237","author":"Hosoki","year":"1997","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bcp.2018.01.017_b0750","doi-asserted-by":"crossref","first-page":"1875","DOI":"10.1097\/HJH.0b013e32833c20d5","article-title":"Systemic peripheral artery relaxation by KCNQ channel openers and hydrogen sulfide","volume":"28","author":"Schleifenbaum","year":"2010","journal-title":"J. Hypertens."},{"key":"10.1016\/j.bcp.2018.01.017_b0755","doi-asserted-by":"crossref","first-page":"H2316","DOI":"10.1152\/ajpheart.00331.2004","article-title":"Hydrogen sulfide-induced relaxation of resistance mesenteric artery beds of rats","volume":"287","author":"Cheng","year":"2004","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.bcp.2018.01.017_b0760","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1152\/physrev.00017.2011","article-title":"Physiological implications of hydrogen sulfide: a whiff exploration that blossomed","volume":"92","author":"Wang","year":"2012","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.bcp.2018.01.017_b0765","doi-asserted-by":"crossref","first-page":"H1953","DOI":"10.1152\/ajpheart.01193.2006","article-title":"Hydrogen sulfide mediates vasoactivity in an O2-dependent manner","volume":"292","author":"Koenitzer","year":"2007","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.bcp.2018.01.017_b0770","article-title":"The mechanism of action and role of hydrogen sulfide in the control of vascular tone","author":"Dongo","year":"2017","journal-title":"Nitric Oxide"},{"key":"10.1016\/j.bcp.2018.01.017_b0775","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1016\/j.lfs.2008.08.006","article-title":"Hydrogen sulfide decreases adenosine triphosphate levels in aortic rings and leads to vasorelaxation via metabolic inhibition","volume":"83","author":"Kiss","year":"2008","journal-title":"Life Sci."},{"key":"10.1016\/j.bcp.2018.01.017_b0780","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1016\/j.bbrc.2007.05.063","article-title":"Hydrogen sulphide regulates intracellular pH in vascular smooth muscle cells","volume":"358","author":"Lee","year":"2007","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bcp.2018.01.017_b0785","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1007\/s10863-008-9166-6","article-title":"The inhibition of mitochondrial cytochrome oxidase by the gases carbon monoxide, nitric oxide, hydrogen cyanide and hydrogen sulfide: chemical mechanism and physiological significance","volume":"40","author":"Cooper","year":"2008","journal-title":"J. Bioenerg. Biomembr."},{"key":"10.1016\/j.bcp.2018.01.017_b0790","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1111\/j.1440-1681.2010.05351.x","article-title":"Interaction of hydrogen sulfide with ion channels","volume":"37","author":"Tang","year":"2010","journal-title":"Clin. Exp. Pharmacol. Physiol."},{"key":"10.1016\/j.bcp.2018.01.017_b0795","doi-asserted-by":"crossref","DOI":"10.3390\/molecules22010063","article-title":"Hydrogen sulfide in the adipose tissue-physiology, pathology and a target for pharmacotherapy","volume":"22","author":"Beltowski","year":"2016","journal-title":"Molecules"},{"key":"10.1016\/j.bcp.2018.01.017_b0800","doi-asserted-by":"crossref","first-page":"41","DOI":"10.14748\/adipo.v2.259","article-title":"Hydrogen sulfide: synthesis and function in the adipose tissue","volume":"2","author":"Be\u0142towski","year":"2010","journal-title":"Adipobiology"},{"key":"10.1016\/j.bcp.2018.01.017_b0805","doi-asserted-by":"crossref","first-page":"H1446","DOI":"10.1152\/ajpheart.00506.2012","article-title":"Hydrogen sulfide dilates rat mesenteric arteries by activating endothelial large-conductance Ca(2)(+)-activated K(+) channels and smooth muscle Ca(2)(+) sparks","volume":"304","author":"Jackson-Weaver","year":"2013","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.bcp.2018.01.017_b0810","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1023\/B:MCBI.0000041858.78005.d2","article-title":"Mechanisms of action of pH-induced effects on vascular smooth muscle","volume":"263","author":"Wray","year":"2004","journal-title":"Mol. Cell. Biochem."},{"key":"10.1016\/j.bcp.2018.01.017_b0815","doi-asserted-by":"crossref","first-page":"G44","DOI":"10.1152\/ajpgi.00413.2010","article-title":"Hydrogen sulfide preconditioning or neutrophil depletion attenuates ischemia-reperfusion-induced mitochondrial dysfunction in rat small intestine","volume":"302","author":"Liu","year":"2012","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"key":"10.1016\/j.bcp.2018.01.017_b0820","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1007\/s00424-009-0737-0","article-title":"Hydrogen sulfide increases calcium-activated potassium (BK) channel activity of rat pituitary tumor cells","volume":"459","author":"Sitdikova","year":"2010","journal-title":"Pflugers Archiv"},{"key":"10.1016\/j.bcp.2018.01.017_b0825","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1089\/ars.2009.2926","article-title":"A crucial role for hydrogen sulfide in oxygen sensing via modulating large conductance calcium-activated potassium channels","volume":"12","author":"Li","year":"2010","journal-title":"Antioxid. Redox Signaling"},{"key":"10.1016\/j.bcp.2018.01.017_b0830","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1085\/jgp.115.5.653","article-title":"Calcium-induced calcium release in smooth muscle: loose coupling between the action potential and calcium release","volume":"115","author":"Collier","year":"2000","journal-title":"J. Gen. Physiol."},{"key":"10.1016\/j.bcp.2018.01.017_b0835","doi-asserted-by":"crossref","first-page":"2709","DOI":"10.1113\/jphysiol.2011.225128","article-title":"Hydrogen sulfide activates Ca(2)(+) sparks to induce cerebral arteriole dilatation","volume":"590","author":"Liang","year":"2012","journal-title":"J. Physiol."},{"key":"10.1016\/j.bcp.2018.01.017_b0840","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/S0024-3205(98)00393-2","article-title":"Mechanisms involved in the cellular calcium homeostasis in vascular smooth muscle: calcium pumps","volume":"64","author":"Marin","year":"1999","journal-title":"Life Sci."},{"key":"10.1016\/j.bcp.2018.01.017_b0845","doi-asserted-by":"crossref","first-page":"9161","DOI":"10.1073\/pnas.1202916109","article-title":"Hydrogen sulfide and nitric oxide are mutually dependent in the regulation of angiogenesis and endothelium-dependent vasorelaxation","volume":"109","author":"Coletta","year":"2012","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.bcp.2018.01.017_b0850","doi-asserted-by":"crossref","first-page":"e53319","DOI":"10.1371\/journal.pone.0053319","article-title":"cGMP-dependent protein kinase contributes to hydrogen sulfide-stimulated vasorelaxation","volume":"7","author":"Bucci","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.bcp.2018.01.017_b0855","doi-asserted-by":"crossref","first-page":"1998","DOI":"10.1161\/ATVBAHA.110.209783","article-title":"Hydrogen sulfide is an endogenous inhibitor of phosphodiesterase activity","volume":"30","author":"Bucci","year":"2010","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.bcp.2018.01.017_b0860","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1161\/01.RES.0000075601.95738.6D","article-title":"Hypercapnic acidosis activates KATP channels in vascular smooth muscles","volume":"92","author":"Wang","year":"2003","journal-title":"Circulation Res."},{"key":"10.1016\/j.bcp.2018.01.017_b0865","doi-asserted-by":"crossref","first-page":"H2169","DOI":"10.1152\/ajpheart.00603.2002","article-title":"Alkaline pH shifts Ca2+ sparks to Ca2+ waves in smooth muscle cells of pressurized cerebral arteries","volume":"283","author":"Heppner","year":"2002","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.bcp.2018.01.017_b0870","doi-asserted-by":"crossref","first-page":"H2088","DOI":"10.1152\/ajpheart.01290.2010","article-title":"Hydrogen sulfide dilates cerebral arterioles by activating smooth muscle cell plasma membrane K(ATP) channels","volume":"300","author":"Liang","year":"2011","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.bcp.2018.01.017_b0875","doi-asserted-by":"crossref","first-page":"96","DOI":"10.2302\/kjm.55.96","article-title":"Duodenal carbonic anhydrase: mucosal protection, luminal chemosensing, and gastric acid disposal","volume":"55","author":"Kaunitz","year":"2006","journal-title":"Keio J. Med."},{"key":"10.1016\/j.bcp.2018.01.017_b0880","doi-asserted-by":"crossref","DOI":"10.1152\/physrev.00052.2003","article-title":"Ion transport pathology in the mechanism of sickle cell dehydration","volume":"85","author":"Lew","year":"2005","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.bcp.2018.01.017_b0885","doi-asserted-by":"crossref","first-page":"4995","DOI":"10.1113\/jphysiol.2010.197392","article-title":"Hydrogen ion dynamics in human red blood cells","volume":"588","author":"Swietach","year":"2010","journal-title":"J. Phssiol."},{"key":"10.1016\/j.bcp.2018.01.017_b0890","doi-asserted-by":"crossref","first-page":"C941","DOI":"10.1152\/ajpcell.00178.2013","article-title":"Transport of H(2)S and HS(\u2212) across the human red blood cell membrane: rapid H(2)S diffusion and AE1-mediated Cl(\u2212)\/HS(\u2212) exchange","volume":"305","author":"Jennings","year":"2013","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"10.1016\/j.bcp.2018.01.017_b0895","doi-asserted-by":"crossref","first-page":"e34562","DOI":"10.1371\/journal.pone.0034562","article-title":"Solubility and permeation of hydrogen sulfide in lipid membranes","volume":"7","author":"Cuevasanta","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.bcp.2018.01.017_b0900","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1016\/0041-008X(90)90321-K","article-title":"Effects of hydrogen sulfide exposure on lung mitochondrial respiratory chain enzymes in rats","volume":"103","author":"Khan","year":"1990","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.bcp.2018.01.017_b0905","doi-asserted-by":"crossref","first-page":"H1554","DOI":"10.1152\/ajpheart.01229.2009","article-title":"Antecedent hydrogen sulfide elicits an anti-inflammatory phenotype in postischemic murine small intestine: role of BK channels","volume":"299","author":"Zuidema","year":"2010","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.bcp.2018.01.017_b0910","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1152\/physiol.00040.2005","article-title":"Calcium-activated potassium channels and the regulation of vascular tone","volume":"21","author":"Ledoux","year":"2006","journal-title":"Physiology"},{"key":"10.1016\/j.bcp.2018.01.017_b0915","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1111\/apha.12630","article-title":"Vascular hyperpolarization in human physiology and cardiovascular risk conditions and disease","volume":"219","author":"Schinzari","year":"2017","journal-title":"Acta Physiol."},{"key":"10.1016\/j.bcp.2018.01.017_b0920","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1111\/j.1440-1681.2004.04071.x","article-title":"Vascular gap junctions and implications for hypertension","volume":"31","author":"Rummery","year":"2004","journal-title":"Clin. Exp. Pharmacol. Physiol."},{"key":"10.1016\/j.bcp.2018.01.017_b0925","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.1161\/01.RES.0000019756.88731.83","article-title":"Involvement of myoendothelial gap junctions in the actions of endothelium-derived hyperpolarizing factor","volume":"90","author":"Sandow","year":"2002","journal-title":"Circulation Res."},{"key":"10.1016\/j.bcp.2018.01.017_b0930","doi-asserted-by":"crossref","first-page":"C1261","DOI":"10.1152\/ajpcell.00195.2008","article-title":"Vasoconstrictive effect of hydrogen sulfide involves downregulation of cAMP in vascular smooth muscle cells","volume":"295","author":"Lim","year":"2008","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"10.1016\/j.bcp.2018.01.017_b0935","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.tox.2006.12.023","article-title":"Direct inhibition of endothelial nitric oxide synthase by hydrogen sulfide: contribution to dual modulation of vascular tension","volume":"232","author":"Kubo","year":"2007","journal-title":"Toxicology"},{"key":"10.1016\/j.bcp.2018.01.017_b0940","doi-asserted-by":"crossref","first-page":"C866","DOI":"10.1152\/ajpcell.00105.2010","article-title":"Bicarbonate-dependent effect of hydrogen sulfide on vascular contractility in rat aortic rings","volume":"299","author":"Liu","year":"2010","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"10.1016\/j.bcp.2018.01.017_b0945","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.ejps.2012.11.001","article-title":"Hydrogen sulfide increases nitric oxide production with calcium-dependent activation of endothelial nitric oxide synthase in endothelial cells","volume":"48","author":"Kida","year":"2013","journal-title":"Eur. J. Pharm. Sci."},{"key":"10.1016\/j.bcp.2018.01.017_b0950","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1016\/j.bcp.2008.12.006","article-title":"Nitric oxide inhibits insulin-degrading enzyme activity and function through S-nitrosylation","volume":"77","author":"Cordes","year":"2009","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.bcp.2018.01.017_b0955","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1440-1681.2006.04316.x","article-title":"Amino acids, arginase and nitric oxide in vascular health","volume":"33","author":"Huynh","year":"2006","journal-title":"Clin. Exp. Pharmacol. Physiol."},{"key":"10.1016\/j.bcp.2018.01.017_b0960","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1152\/physrev.00029.2006","article-title":"Nitric oxide and peroxynitrite in health and disease","volume":"87","author":"Pacher","year":"2007","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.bcp.2018.01.017_b0965","doi-asserted-by":"crossref","first-page":"2003","DOI":"10.1056\/NEJMsa063904","article-title":"Shattuck Lecture. Nitric oxide and cyclic GMP in cell signaling and drug development","volume":"355","author":"Murad","year":"2006","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.bcp.2018.01.017_b0970","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.ccm.2006.12.002","article-title":"The nitric oxide\/cGMP signaling pathway in pulmonary hypertension","volume":"28","author":"Klinger","year":"2007","journal-title":"Clin. Chest. Med."},{"key":"10.1016\/j.bcp.2018.01.017_b0975","series-title":"Cell Signalling Biology","author":"Berridge","year":"2014"},{"key":"10.1016\/j.bcp.2018.01.017_b0980","doi-asserted-by":"crossref","first-page":"31888","DOI":"10.18632\/oncotarget.16649","article-title":"Sulfhydration-associated phosphodiesterase 5A dimerization mediates vasorelaxant effect of hydrogen sulfide","volume":"8","author":"Sun","year":"2017","journal-title":"Oncotarget"},{"key":"10.1016\/j.bcp.2018.01.017_b0985","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.1096\/fj.12-221580","article-title":"Increased cGMP promotes healthy expansion and browning of white adipose tissue","volume":"27","author":"Mitschke","year":"2013","journal-title":"FASEB J."},{"key":"10.1016\/j.bcp.2018.01.017_b0990","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/S0008-6363(02)00327-9","article-title":"Vasoprotection by nitric oxide: mechanisms and therapeutic potential","volume":"55","author":"Gewaltig","year":"2002","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.bcp.2018.01.017_b0995","doi-asserted-by":"crossref","first-page":"19770","DOI":"10.1074\/jbc.M006266200","article-title":"Phosphorylation and regulation of G-protein-activated phospholipase C-beta 3 by cGMP-dependent protein kinases","volume":"276","author":"Xia","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bcp.2018.01.017_b1000","doi-asserted-by":"crossref","first-page":"4222","DOI":"10.1038\/sj.emboj.7600440","article-title":"IRAG is essential for relaxation of receptor-triggered smooth muscle contraction by cGMP kinase","volume":"23","author":"Geiselhoringer","year":"2004","journal-title":"EMBO J."},{"key":"10.1016\/j.bcp.2018.01.017_b1005","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1042\/bj2520269","article-title":"Cyclic GMP-dependent protein kinase phosphorylates phospholamban in isolated sarcoplasmic reticulum from cardiac and smooth muscle","volume":"252","author":"Raeymaekers","year":"1988","journal-title":"Biochem. J."},{"key":"10.1016\/j.bcp.2018.01.017_b1010","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1124\/jpet.105.096115","article-title":"Kv channels contribute to nitric oxide- and atrial natriuretic peptide-induced relaxation of a rat conduit artery","volume":"317","author":"Tanaka","year":"2006","journal-title":"J. Pharmacol. Exp. Ther."},{"issue":"Pt. 1","key":"10.1016\/j.bcp.2018.01.017_b1015","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1113\/jphysiol.1995.sp020789","article-title":"Nitric oxide hyperpolarizes rabbit mesenteric arteries via ATP-sensitive potassium channels","volume":"486","author":"Murphy","year":"1995","journal-title":"J. Physiol."},{"key":"10.1016\/j.bcp.2018.01.017_b1020","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1161\/01.HYP.0000121882.42731.6b","article-title":"Nitric oxide donor sodium nitroprusside dilates rat small arteries by activation of inward rectifier potassium channels","volume":"43","author":"Schubert","year":"2004","journal-title":"Hypertension"},{"key":"10.1016\/j.bcp.2018.01.017_b1025","doi-asserted-by":"crossref","first-page":"C299","DOI":"10.1152\/ajpcell.1993.265.1.C299","article-title":"cGMP-dependent protein kinase activates Ca-activated K channels in cerebral artery smooth muscle cells","volume":"265","author":"Robertson","year":"1993","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.bcp.2018.01.017_b1030","doi-asserted-by":"crossref","first-page":"9360","DOI":"10.1073\/pnas.85.23.9360","article-title":"Guanosine 5'-monophosphate modulates gating of high-conductance Ca2+-activated K+ channels in vascular smooth muscle cells","volume":"85","author":"Williams","year":"1988","journal-title":"PNAS"},{"key":"10.1016\/j.bcp.2018.01.017_b1035","doi-asserted-by":"crossref","first-page":"H417","DOI":"10.1152\/ajpheart.01130.2008","article-title":"Inhibition of TRPC1\/TRPC3 by PKG contributes to NO-mediated vasorelaxation","volume":"297","author":"Chen","year":"2009","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.bcp.2018.01.017_b1040","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1007\/s00424-002-0825-x","article-title":"ATP and nitric oxide modulate a Ca(2+)-activated non-selective cation current in macrovascular endothelial cells","volume":"444","author":"Suh","year":"2002","journal-title":"Pflugers Archiv"},{"key":"10.1016\/j.bcp.2018.01.017_b1045","doi-asserted-by":"crossref","first-page":"C1743","DOI":"10.1152\/ajpcell.2001.281.6.C1743","article-title":"Regulation of cardiac and smooth muscle Ca(2+) channels (Ca(V)1.2a, b) by protein kinases.","volume":"281","author":"Keef","year":"2001","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"10.1016\/j.bcp.2018.01.017_b1050","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1007\/s004240050281","article-title":"Sodium nitroprusside and cGMP decrease Ca2+ channel availability in basilar artery smooth muscle cells","volume":"433","author":"Tewari","year":"1997","journal-title":"Pflugers Archiv"},{"key":"10.1016\/j.bcp.2018.01.017_b1055","doi-asserted-by":"crossref","first-page":"4209","DOI":"10.1113\/jphysiol.2008.156083","article-title":"Nitric oxide-cGMP-protein kinase G pathway negatively regulates vascular transient receptor potential channel TRPC6","volume":"586","author":"Takahashi","year":"2008","journal-title":"J. Physiol."},{"key":"10.1016\/j.bcp.2018.01.017_b1060","doi-asserted-by":"crossref","first-page":"324","DOI":"10.3389\/fphys.2012.00324","article-title":"TRP channels: sensors and transducers of gasotransmitter signals","volume":"3","author":"Takahashi","year":"2012","journal-title":"Front. Physiol."},{"key":"10.1016\/j.bcp.2018.01.017_b1065","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1161\/CIRCRESAHA.107.153981","article-title":"cGMP-dependent relaxation of smooth muscle is coupled with the change in the phosphorylation of myosin phosphatase","volume":"101","author":"Nakamura","year":"2007","journal-title":"Circ. Res."},{"key":"10.1016\/j.bcp.2018.01.017_b1070","doi-asserted-by":"crossref","first-page":"L1306","DOI":"10.1152\/ajplung.00189.2007","article-title":"Rho kinase and Ca2+ entry mediate increased pulmonary and systemic vascular resistance in L-NAME-treated rats","volume":"293","author":"Dhaliwal","year":"2007","journal-title":"Am. J. Physiol. Lung Cell. Mol. Physiol."},{"key":"10.1016\/j.bcp.2018.01.017_b1075","doi-asserted-by":"crossref","first-page":"G1006","DOI":"10.1152\/ajpgi.00465.2002","article-title":"Inhibition of sustained smooth muscle contraction by PKA and PKG preferentially mediated by phosphorylation of RhoA","volume":"284","author":"Murthy","year":"2003","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"key":"10.1016\/j.bcp.2018.01.017_b1080","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1038\/nm1119","article-title":"S-Glutathiolation by peroxynitrite activates SERCA during arterial relaxation by nitric oxide","volume":"10","author":"Adachi","year":"2004","journal-title":"Nat. Med."},{"key":"10.1016\/j.bcp.2018.01.017_b1085","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1038\/368850a0","article-title":"Nitric oxide directly activates calcium-dependent potassium channels in vascular smooth muscle","volume":"368","author":"Bolotina","year":"1994","journal-title":"Nature"},{"key":"10.1016\/j.bcp.2018.01.017_b1090","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.niox.2006.06.007","article-title":"Effect of endogenous and exogenous nitric oxide on calcium sparks as targets for vasodilation in rat cerebral artery","volume":"16","author":"Mandala","year":"2007","journal-title":"Nitric Oxide"},{"key":"10.1016\/j.bcp.2018.01.017_b1095","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/S1063-5823(10)66005-X","article-title":"Regulation of ryanodine receptor ion channels through posttranslational modifications","volume":"66","author":"Meissner","year":"2010","journal-title":"Curr. Top. Membr."},{"key":"10.1016\/j.bcp.2018.01.017_b1100","doi-asserted-by":"crossref","first-page":"6904327","DOI":"10.1155\/2016\/6904327","article-title":"Interaction of hydrogen sulfide with nitric oxide in the cardiovascular system","volume":"2016","author":"Nagpure","year":"2016","journal-title":"Oxid. Med. Cell. Longevity"},{"key":"10.1016\/j.bcp.2018.01.017_b1105","doi-asserted-by":"crossref","DOI":"10.3892\/mmr.2017.7328","article-title":"Hydrogen sulfide facilities production of nitric oxide via the Akt\/endothelial nitric oxide synthases signaling pathway to protect human umbilical vein endothelial cells from injury by angiotensin II","author":"Cui","year":"2017","journal-title":"Mol. Med. Rep."},{"key":"10.1016\/j.bcp.2018.01.017_b1110","doi-asserted-by":"crossref","first-page":"104","DOI":"10.3389\/fphys.2011.00104","article-title":"Hydrogen sulfide increases nitric oxide production from endothelial cells by an akt-dependent mechanism","volume":"2","author":"Predmore","year":"2011","journal-title":"Front. Physiol."},{"key":"10.1016\/j.bcp.2018.01.017_b1115","doi-asserted-by":"crossref","first-page":"9161","DOI":"10.1073\/pnas.1202916109","article-title":"Hydrogen sulfide and nitric oxide are mutually dependent in the regulation of angiogenesis and endothelium-dependent vasorelaxation","volume":"109","author":"Ciro Coletta","year":"2012","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.bcp.2018.01.017_b1120","doi-asserted-by":"crossref","DOI":"10.1111\/bph.13815","article-title":"Nitric oxide and hydrogen sulfide: the gasotransmitter paradigm of the vascular system","author":"Cirino","year":"2017","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.bcp.2018.01.017_b1125","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1016\/j.atherosclerosis.2009.10.004","article-title":"Modulation of Ca(2+) signalling in human vascular endothelial cells by hydrogen sulfide","volume":"209","author":"Bauer","year":"2010","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.bcp.2018.01.017_b1130","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.ceca.2014.07.010","article-title":"Hydrogen sulphide triggers VEGF-induced intracellular Ca(2)(+) signals in human endothelial cells but not in their immature progenitors","volume":"56","author":"Potenza","year":"2014","journal-title":"Cell Calcium"},{"issue":"Suppl. 1","key":"10.1016\/j.bcp.2018.01.017_b1135","first-page":"S42","article-title":"Diallyl disulfide and diallyl trisulfide protect endothelial nitric oxide synthase against damage by oxidized low-density lipoprotein","volume":"54","author":"Lei","year":"2010","journal-title":"Mol. Nutr. Food Res."},{"key":"10.1016\/j.bcp.2018.01.017_b1140","doi-asserted-by":"crossref","first-page":"ra87","DOI":"10.1126\/scisignal.2005478","article-title":"The coordination of S-sulfhydration, S-nitrosylation, and phosphorylation of endothelial nitric oxide synthase by hydrogen sulfide","volume":"7","author":"Altaany","year":"2014","journal-title":"Sci. Signal."},{"key":"10.1016\/j.bcp.2018.01.017_b1145","doi-asserted-by":"crossref","first-page":"10","DOI":"10.4161\/chan.2.1.6053","article-title":"Ca2+ signaling in smooth muscle: TRPC6 NCX and LNats in nanodomains","volume":"2","author":"Poburko","year":"2008","journal-title":"Channels"},{"key":"10.1016\/j.bcp.2018.01.017_b1150","article-title":"Hydrogen sulfide improves endothelial dysfunction in hypertension by activating peroxisome proliferator-activated receptor delta\/endothelial nitric oxide synthase signaling","author":"Xiao","year":"2017","journal-title":"J. Hypertens."},{"key":"10.1016\/j.bcp.2018.01.017_b1155","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1007\/s00424-014-1526-y","article-title":"Hydrogen sulfide impairs shear stress-induced vasodilation in mouse coronary arteries","volume":"467","author":"Chai","year":"2015","journal-title":"Pflugers Archiv"},{"key":"10.1016\/j.bcp.2018.01.017_b1160","first-page":"e657","article-title":"Nitric oxide and insulin resistance","volume":"2","author":"Kobayashi","year":"2015","journal-title":"Immunoendocrinology"},{"key":"10.1016\/j.bcp.2018.01.017_b1165","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.bbrc.2010.02.136","article-title":"NO-synthase independent NO generation in mammals","volume":"396","author":"Lundberg","year":"2010","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bcp.2018.01.017_b1170","doi-asserted-by":"crossref","first-page":"12231","DOI":"10.1016\/S0021-9258(18)31375-9","article-title":"Nitric oxide synthase structure and mechanism","volume":"268","author":"Marletta","year":"1993","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bcp.2018.01.017_b1175","doi-asserted-by":"crossref","first-page":"R1608","DOI":"10.1152\/ajpregu.00207.2006","article-title":"Hydrogen sulfide downregulates the aortic L-arginine\/nitric oxide pathway in rats","volume":"293","author":"Geng","year":"2007","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.bcp.2018.01.017_b1180","doi-asserted-by":"crossref","first-page":"7075682","DOI":"10.1155\/2016\/7075682","article-title":"Vasorelaxant effect of a new hydrogen sulfide-nitric oxide conjugated donor in isolated rat aortic rings through cGMP pathway","volume":"2016","author":"Wu","year":"2016","journal-title":"Oxid. Med. Cell. Longevity"},{"key":"10.1016\/j.bcp.2018.01.017_b1185","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1139\/y03-077","article-title":"Modulation of endogenous production of H2S in rat tissues","volume":"81","author":"Zhao","year":"2003","journal-title":"Can. J. Physiol. Pharmacol."},{"key":"10.1016\/j.bcp.2018.01.017_b1190","first-page":"8","article-title":"Hydrogen sulfide increases nitric oxide production and subsequent s-nitrosylation in endothelial cells","volume":"2014","author":"Chen","year":"2014","journal-title":"Sci. World J."},{"key":"10.1016\/j.bcp.2018.01.017_b1195","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.niox.2014.05.014","article-title":"Hydrogen sulfide and nitric oxide interactions in inflammation","volume":"41","author":"Lo Faro","year":"2014","journal-title":"Nitric Oxide"},{"key":"10.1016\/j.bcp.2018.01.017_b1200","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.redox.2013.05.001","article-title":"A tale of two gases: NO and H2S, foes or friends for life?","volume":"1","author":"Kolluru","year":"2013","journal-title":"Redox. Biol."},{"key":"10.1016\/j.bcp.2018.01.017_b1205","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.freeradbiomed.2012.11.005","article-title":"Potential biological chemistry of hydrogen sulfide (H(2)S) with the nitrogen oxides","volume":"55","author":"King","year":"2013","journal-title":"Free Radical Biol. Med."},{"key":"10.1016\/j.bcp.2018.01.017_b1210","doi-asserted-by":"crossref","first-page":"E4651","DOI":"10.1073\/pnas.1509277112","article-title":"Key bioactive reaction products of the NO\/H(2)S interaction are S\/N-hybrid species, polysulfides, and nitroxyl","volume":"112","author":"Cortese-Krott","year":"2015","journal-title":"PNAS"},{"key":"10.1016\/j.bcp.2018.01.017_b1215","doi-asserted-by":"crossref","first-page":"45995","DOI":"10.1038\/srep45995","article-title":"Polysulfides (H2Sn) produced from the interaction of hydrogen sulfide (H2S) and nitric oxide (NO) activate TRPA1 channels","volume":"7","author":"Miyamoto","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bcp.2018.01.017_b1220","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1007\/978-3-319-18144-8_2","article-title":"Persulfidation (S-sulfhydration) and H2S","volume":"230","author":"Filipovic","year":"2015","journal-title":"Handb. Exp. Pharmacol."},{"key":"10.1016\/j.bcp.2018.01.017_b1225","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.niox.2014.12.008","article-title":"The reaction products of sulfide and S-nitrosoglutathione are potent vasorelaxants","volume":"46","author":"Berenyiova","year":"2015","journal-title":"Nitric Oxide"},{"key":"10.1016\/j.bcp.2018.01.017_b1230","doi-asserted-by":"crossref","first-page":"12016","DOI":"10.1021\/ja3009693","article-title":"Chemical characterization of the smallest S-nitrosothiol, HSNO; cellular cross-talk of H2S and S-nitrosothiols","volume":"134","author":"Filipovic","year":"2012","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.bcp.2018.01.017_b1235","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/j.cardiores.2006.11.018","article-title":"The nitroxyl anion (HNO) is a potent dilator of rat coronary vasculature","volume":"73","author":"Favaloro","year":"2007","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.bcp.2018.01.017_b1240","doi-asserted-by":"crossref","first-page":"4381","DOI":"10.1038\/ncomms5381","article-title":"H2S and NO cooperatively regulate vascular tone by activating a neuroendocrine HNO-TRPA1-CGRP signalling pathway","volume":"5","author":"Eberhardt","year":"2014","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bcp.2018.01.017_b1245","doi-asserted-by":"crossref","first-page":"1779","DOI":"10.1007\/s00726-015-1986-1","article-title":"A review and discussion of platelet nitric oxide and nitric oxide synthase: do blood platelets produce nitric oxide from L-arginine or nitrite?","volume":"47","author":"Gambaryan","year":"2015","journal-title":"Amino Acids"},{"key":"10.1016\/j.bcp.2018.01.017_b1250","doi-asserted-by":"crossref","first-page":"C236","DOI":"10.1152\/ajpcell.1994.267.1.C236","article-title":"Regulation of calcium mobilization and entry in human platelets by endothelium-derived factors","volume":"267","author":"Geiger","year":"1994","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.bcp.2018.01.017_b1255","doi-asserted-by":"crossref","first-page":"1574","DOI":"10.1111\/jth.12271","article-title":"Phosphorylation of CalDAG-GEFI by protein kinase A prevents Rap1b activation","volume":"11","author":"Subramanian","year":"2013","journal-title":"J. Thrombosis Haemostasis"},{"key":"10.1016\/j.bcp.2018.01.017_b1260","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1111\/j.1538-7836.2011.04576.x","article-title":"Novel roles of cAMP\/cGMP-dependent signaling in platelets","volume":"10","author":"Smolenski","year":"2012","journal-title":"J. Thrombosis Haemostasis"},{"key":"10.1016\/j.bcp.2018.01.017_b1265","doi-asserted-by":"crossref","first-page":"H637","DOI":"10.1152\/ajpheart.00622.2002","article-title":"Inhaled NO inhibits platelet aggregation and elevates plasma but not intraplatelet cGMP in healthy human volunteers","volume":"285","author":"Beghetti","year":"2003","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.bcp.2018.01.017_b1270","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/S0014-5793(98)01633-0","article-title":"Inhibition of platelet aggregation by S-nitroso-cysteine via cGMP-independent mechanisms: evidence of inhibition of thromboxane A2 synthesis in human blood platelets","volume":"442","author":"Tsikas","year":"1999","journal-title":"FEBS Lett."},{"key":"10.1016\/j.bcp.2018.01.017_b1275","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1161\/01.CIR.97.3.263","article-title":"Cell-free and erythrocytic S-nitrosohemoglobin inhibits human platelet aggregation","volume":"97","author":"Pawloski","year":"1998","journal-title":"Circulation"},{"key":"10.1016\/j.bcp.2018.01.017_b1280","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1016\/0003-9861(90)90493-I","article-title":"Properties of a novel nitric oxide-stimulated ADP-ribosyltransferase","volume":"279","author":"Brune","year":"1990","journal-title":"Arch. Biochem. Biophy."},{"key":"10.1016\/j.bcp.2018.01.017_b1285","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1006\/bbrc.1996.0821","article-title":"Nitric oxide inhibits ATP-dependent Ca2+ uptake into platelet membrane vesicles","volume":"222","author":"Pernollet","year":"1996","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bcp.2018.01.017_b1290","doi-asserted-by":"crossref","first-page":"15812","DOI":"10.1073\/pnas.1309049110","article-title":"Hydrogen sulphide pathway contributes to the enhanced human platelet aggregation in hyperhomocysteinemia","volume":"110","author":"di Villa","year":"2013","journal-title":"PNAS"},{"key":"10.1016\/j.bcp.2018.01.017_b1295","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.yexcr.2017.06.013","article-title":"Calcium sensing receptor initiating cystathionine-gamma-lyase\/hydrogen sulfide pathway to inhibit platelet activation in hyperhomocysteinemia rat","volume":"358","author":"Wang","year":"2017","journal-title":"Exp. Cell. Res."},{"key":"10.1016\/j.bcp.2018.01.017_b1300","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.ejphar.2006.12.011","article-title":"Hydrogen sulfide inhibits human platelet aggregation","volume":"559","author":"Zagli","year":"2007","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.bcp.2018.01.017_b1305","doi-asserted-by":"crossref","first-page":"e112","DOI":"10.1016\/j.thromres.2013.07.010","article-title":"The anti-thrombotic effect of hydrogen sulfide is partly mediated by an upregulation of nitric oxide synthases","volume":"132","author":"Kram","year":"2013","journal-title":"Thromb. Res."},{"key":"10.1016\/j.bcp.2018.01.017_b1310","first-page":"15607","article-title":"Hydrogen sulfide exerts antithrombotic effects and inhibits deep vein thrombosis through NOS-PECAM-1 signaling pathway","volume":"9","author":"Gang Li","year":"2016","journal-title":"Int. J. Clin. Exp. Med."},{"key":"10.1016\/j.bcp.2018.01.017_b1315","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.hlc.2014.05.019","article-title":"Hydrogen sulfide inhibits human platelet aggregation in vitro in part by interfering gap junction channels: effects of ACS14, a hydrogen sulfide-releasing aspirin","volume":"24","author":"Gao","year":"2015","journal-title":"Heart Lung Circ."},{"key":"10.1016\/j.bcp.2018.01.017_b1320","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1248\/bpb.b13-00018","article-title":"Inhibition by hydrogen sulfide of rabbit platelet aggregation and calcium mobilization","volume":"36","author":"Nishikawa","year":"2013","journal-title":"Biol. Pharm. Bull."},{"key":"10.1016\/j.bcp.2018.01.017_b1325","doi-asserted-by":"crossref","first-page":"1678","DOI":"10.1016\/j.clinbiochem.2012.08.025","article-title":"Antioxidative properties of hydrogen sulfide may involve in its antiadhesive action on blood platelets","volume":"45","author":"Morel","year":"2012","journal-title":"Clin. Biochem."},{"key":"10.1016\/j.bcp.2018.01.017_b1330","doi-asserted-by":"crossref","first-page":"166","DOI":"10.3109\/09537104.2013.786823","article-title":"Effect of the hydrogen sulfide donor GYY4137 on platelet activation and microvascular thrombus formation in mice","volume":"25","author":"Grambow","year":"2014","journal-title":"Platelets"},{"key":"10.1016\/j.bcp.2018.01.017_b1335","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1016\/S1567-5769(01)00086-8","article-title":"Nitric oxide in immunity and inflammation","volume":"1","author":"Coleman","year":"2001","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.bcp.2018.01.017_b1340","first-page":"469","article-title":"Nitric oxide and superoxide in inflammation and immune regulation","volume":"54","author":"Guzik","year":"2003","journal-title":"J. Physiol. Pharmacol."},{"key":"10.1016\/j.bcp.2018.01.017_b1345","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1515\/BC.2003.152","article-title":"Regulation of the expression of inducible nitric oxide synthase","volume":"384","author":"Kleinert","year":"2003","journal-title":"Biol. Chem."},{"key":"10.1016\/j.bcp.2018.01.017_b1350","doi-asserted-by":"crossref","first-page":"I45","DOI":"10.1161\/01.HYP.23.1_Suppl.I45","article-title":"Expression of nitric oxide synthase by cytokines in vascular smooth muscle cells","volume":"23","author":"Koide","year":"1994","journal-title":"Hypertension"},{"key":"10.1016\/j.bcp.2018.01.017_b1355","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1016\/S0008-6363(99)00171-6","article-title":"Nitric oxide and the proliferation of vascular smooth muscle cells","volume":"43","author":"Jeremy","year":"1999","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.bcp.2018.01.017_b1360","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1016\/j.yjmcc.2005.06.012","article-title":"A negative feedback mechanism involving nitric oxide and nuclear factor kappa-B modulates endothelial nitric oxide synthase transcription","volume":"39","author":"Grumbach","year":"2005","journal-title":"J. Mol. Cell. Cardiol."},{"key":"10.1016\/j.bcp.2018.01.017_b1365","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1093\/jnen\/60.9.893","article-title":"Inhibitory action of nitric oxide on circulating tumor necrosis factor-induced NF-kappaB activity and COX-2 transcription in the endothelium of the brain capillaries","volume":"60","author":"Blais","year":"2001","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1016\/j.bcp.2018.01.017_b1370","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1161\/hs0202.102363","article-title":"Combined endothelial nitric oxide synthase upregulation and caveolin-1 downregulation decrease leukocyte adhesion in pial venules of ovariectomized female rats","volume":"33","author":"Santizo","year":"2002","journal-title":"Stroke"},{"key":"10.1016\/j.bcp.2018.01.017_b1375","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1186\/1476-9255-9-28","article-title":"Inhibition of nitric oxide synthesis enhances leukocyte rolling and adhesion in human microvasculature","volume":"9","author":"Hossain","year":"2012","journal-title":"J. Inflamm."},{"key":"10.1016\/j.bcp.2018.01.017_b1380","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1189\/jlb.1011513","article-title":"Neuronal nitric oxide synthase regulates endothelial inflammation","volume":"91","author":"Chakrabarti","year":"2012","journal-title":"J. Leukoc. Biol."},{"key":"10.1016\/j.bcp.2018.01.017_b1385","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1089\/ars.2009.2899","article-title":"The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages","volume":"12","author":"Whiteman","year":"2010","journal-title":"Antioxid. Redox Signaling"},{"key":"10.1016\/j.bcp.2018.01.017_b1390","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1089\/ars.2009.2956","article-title":"Low levels of hydrogen sulfide in the blood of diabetes patients and streptozotocin-treated rats causes vascular inflammation?","volume":"12","author":"Jain","year":"2010","journal-title":"Antioxid. Redox Signaling"},{"key":"10.1016\/j.bcp.2018.01.017_b1395","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1016\/j.phrs.2016.09.017","article-title":"H2S dependent and independent anti-inflammatory activity of zofenoprilat in cells of the vascular wall","volume":"113","author":"Monti","year":"2016","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.bcp.2018.01.017_b1400","doi-asserted-by":"crossref","first-page":"2118","DOI":"10.1096\/fj.06-6270fje","article-title":"Hydrogen sulfide is an endogenous modulator of leukocyte-mediated inflammation","volume":"20","author":"Zanardo","year":"2006","journal-title":"FASEB J."},{"key":"10.1016\/j.bcp.2018.01.017_b1405","doi-asserted-by":"crossref","first-page":"1210","DOI":"10.1053\/j.gastro.2005.07.060","article-title":"Inhibition of hydrogen sulfide generation contributes to gastric injury caused by anti-inflammatory nonsteroidal drugs","volume":"129","author":"Fiorucci","year":"2005","journal-title":"Gastroenterology"},{"key":"10.1016\/j.bcp.2018.01.017_b1410","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.freeradbiomed.2006.03.021","article-title":"Hydrogen sulfide inhibits nitric oxide production and nuclear factor-kappaB via heme oxygenase-1 expression in RAW264.7 macrophages stimulated with lipopolysaccharide","volume":"41","author":"Oh","year":"2006","journal-title":"Free Radical Biol. Med."},{"key":"10.1016\/j.bcp.2018.01.017_b1415","doi-asserted-by":"crossref","first-page":"2255","DOI":"10.1016\/j.cellsig.2013.07.010","article-title":"Dysregulation of cystathionine gamma-lyase (CSE)\/hydrogen sulfide pathway contributes to ox-LDL-induced inflammation in macrophage","volume":"25","author":"Wang","year":"2013","journal-title":"Cell. Signal."},{"key":"10.1016\/j.bcp.2018.01.017_b1420","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1258\/ebm.2010.010308","article-title":"Hydrogen sulfide inhibits macrophage-derived foam cell formation","volume":"236","author":"Zhao","year":"2011","journal-title":"Exp. Biol. Med."},{"key":"10.1016\/j.bcp.2018.01.017_b1425","doi-asserted-by":"crossref","first-page":"e19766","DOI":"10.1371\/journal.pone.0019766","article-title":"Hydrogen sulfide attenuated tumor necrosis factor-alpha-induced inflammatory signaling and dysfunction in vascular endothelial cells","volume":"6","author":"Pan","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.bcp.2018.01.017_b1430","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.ijcard.2011.12.059","article-title":"S-propargyl-cysteine, a novel hydrogen sulfide-modulated agent, attenuated tumor necrosis factor-alpha-induced inflammatory signaling and dysfunction in endothelial cells","volume":"155","author":"Pan","year":"2012","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.bcp.2018.01.017_b1435","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1073\/pnas.89.1.444","article-title":"S-nitrosylation of proteins with nitric oxide: synthesis and characterization of biologically active compounds","volume":"89","author":"Stamler","year":"1992","journal-title":"PNAS"},{"key":"10.1016\/j.bcp.2018.01.017_b1440","doi-asserted-by":"crossref","first-page":"303","DOI":"10.2174\/157339912800840514","article-title":"The good and bad effects of cysteine S-nitrosylation and tyrosine nitration upon insulin exocytosis: a balancing act","volume":"8","author":"Wiseman","year":"2012","journal-title":"Curr. Diabetes Rev."},{"key":"10.1016\/j.bcp.2018.01.017_b1445","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4137\/BCI.S36141","article-title":"Protein modifications as manifestations of hyperglycemic glucotoxicity in diabetes and its complications","volume":"9","author":"Zheng","year":"2016","journal-title":"Biochem. Insights"},{"key":"10.1016\/j.bcp.2018.01.017_b1450","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1016\/S0092-8674(01)00495-0","article-title":"Nitrosylation. the prototypic redox-based signaling mechanism","volume":"106","author":"Stamler","year":"2001","journal-title":"Cell"},{"key":"10.1016\/j.bcp.2018.01.017_b1455","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0003-9861(02)00490-3","article-title":"Nitrosylation: the next phosphorylation?","volume":"408","author":"Mannick","year":"2002","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.bcp.2018.01.017_b1460","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1124\/mol.63.5.1148","article-title":"Role of S-nitrosation of cysteine residues in long-lasting inhibitory effect of nitric oxide on arterial tone","volume":"63","author":"Alencar","year":"2003","journal-title":"Mol. Pharmacol."},{"key":"10.1016\/j.bcp.2018.01.017_b1465","first-page":"S_415","article-title":"Abstract 3379: cGMP specific phosphodiesterase type 5A activity is regulated by s-nitrosylation at Cys 181","volume":"118","author":"Murray","year":"2016","journal-title":"Circulation"},{"key":"10.1016\/j.bcp.2018.01.017_b1470","doi-asserted-by":"crossref","first-page":"12312","DOI":"10.1073\/pnas.0703944104","article-title":"Desensitization of soluble guanylyl cyclase, the NO receptor, by S-nitrosylation","volume":"104","author":"Sayed","year":"2007","journal-title":"PNAS"},{"key":"10.1016\/j.bcp.2018.01.017_b1475","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1097\/FJC.0b013e3181fef9cb","article-title":"S-nitrosylation Inhibits protein kinase C-mediated contraction in mouse aorta","volume":"57","author":"Choi","year":"2011","journal-title":"J. Cardiovasc. Pharmacol."},{"key":"10.1016\/j.bcp.2018.01.017_b1480","doi-asserted-by":"crossref","first-page":"L136","DOI":"10.1152\/ajplung.00230.2005","article-title":"S-nitrosoglutathione inhibits alpha1-adrenergic receptor-mediated vasoconstriction and ligand binding in pulmonary artery","volume":"290","author":"Nozik-Grayck","year":"2006","journal-title":"Am. J. Physiol. Lung Cell. Mol. Physiol."},{"key":"10.1016\/j.bcp.2018.01.017_b1485","doi-asserted-by":"crossref","first-page":"19601","DOI":"10.1074\/jbc.272.31.19601","article-title":"Modulation of bradykinin receptor ligand binding affinity and its coupled G-proteins by nitric oxide","volume":"272","author":"Miyamoto","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bcp.2018.01.017_b1490","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1038\/sj.bjp.0706725","article-title":"S-nitrosylation of cysteine 289 of the AT1 receptor decreases its binding affinity for angiotensin II","volume":"148","author":"Leclerc","year":"2006","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.bcp.2018.01.017_b1495","doi-asserted-by":"crossref","first-page":"14797","DOI":"10.1074\/jbc.M008244200","article-title":"S-nitrosation controls gating and conductance of the alpha 1 subunit of class C L-type Ca(2+) channels","volume":"276","author":"Poteser","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bcp.2018.01.017_b1500","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1161\/ATVBAHA.110.215939","article-title":"Compartmentalized connexin 43 s-nitrosylation\/denitrosylation regulates heterocellular communication in the vessel wall","volume":"31","author":"Straub","year":"2011","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.bcp.2018.01.017_b1505","doi-asserted-by":"crossref","DOI":"10.1002\/prp2.343","article-title":"Inhibition of RhoA\/Rho kinase pathway and smooth muscle contraction by hydrogen sulfide","volume":"5","author":"Nalli","year":"2017","journal-title":"Pharmacol. Res. Perspect."},{"key":"10.1016\/j.bcp.2018.01.017_b1510","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1038\/sj.bjp.0705698","article-title":"Endothelium-dependent smooth muscle hyperpolarization: do gap junctions provide a unifying hypothesis?","volume":"141","author":"Griffith","year":"2004","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.bcp.2018.01.017_b1515","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1111\/1755-5922.12128","article-title":"A novel hydrogen sulfide prodrug, SG1002, promotes hydrogen sulfide and nitric oxide bioavailability in heart failure patients","volume":"33","author":"Polhemus","year":"2015","journal-title":"Cardiovasc. Ther."},{"key":"10.1016\/j.bcp.2018.01.017_b1520","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1161\/HYPERTENSIONAHA.115.06624","article-title":"Taurine supplementation lowers blood pressure and improves vascular function in prehypertension: randomized, double-blind placebo-controlled study","volume":"67","author":"Sun","year":"2016","journal-title":"Hypertension"},{"key":"10.1016\/j.bcp.2018.01.017_b1525","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1089\/ars.2017.7076","article-title":"Hydrogen sulfide and polysulfide signaling","volume":"27","author":"Kimura","year":"2017","journal-title":"Antioxid. Redox Signaling"}],"container-title":["Biochemical Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006295218300170?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006295218300170?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T13:01:05Z","timestamp":1757768465000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006295218300170"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3]]},"references-count":305,"alternative-id":["S0006295218300170"],"URL":"https:\/\/doi.org\/10.1016\/j.bcp.2018.01.017","relation":{},"ISSN":["0006-2952"],"issn-type":[{"value":"0006-2952","type":"print"}],"subject":[],"published":{"date-parts":[[2018,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Regulation of vascular tone homeostasis by NO and H2S: Implications in hypertension","name":"articletitle","label":"Article Title"},{"value":"Biochemical Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bcp.2018.01.017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}