{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T08:01:59Z","timestamp":1777536119460,"version":"3.51.4"},"reference-count":57,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,6,1]],"date-time":"2020-06-01T00:00:00Z","timestamp":1590969600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,6,1]],"date-time":"2020-06-01T00:00:00Z","timestamp":1590969600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical Pharmacology"],"published-print":{"date-parts":[[2020,6]]},"DOI":"10.1016\/j.bcp.2020.113857","type":"journal-article","created":{"date-parts":[[2020,2,13]],"date-time":"2020-02-13T21:17:49Z","timestamp":1581628669000},"page":"113857","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"special_numbering":"C","title":["NOSH-aspirin (NBS-1120) inhibits pancreatic cancer cell growth in a xenograft mouse model: Modulation of FoxM1, p53, NF-\u03baB, iNOS, caspase-3 and ROS"],"prefix":"10.1016","volume":"176","author":[{"given":"Mitali","family":"Chattopadhyay","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ravinder","family":"Kodela","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriela","family":"Santiago","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thuy Tien C.","family":"Le","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Niharika","family":"Nath","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4060-7283","authenticated-orcid":false,"given":"Khosrow","family":"Kashfi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.bcp.2020.113857_b0005","first-page":"7","article-title":"Cancer statistics","volume":"67","author":"Siegel","year":"2017","journal-title":"CA: Cancer J. Clinicians"},{"issue":"11","key":"10.1016\/j.bcp.2020.113857_b0010","doi-asserted-by":"crossref","first-page":"2913","DOI":"10.1158\/0008-5472.CAN-14-0155","article-title":"Projecting cancer incidence and deaths to 2030: the unexpected burden of thyroid, liver, and pancreas cancers in the United States","volume":"74","author":"Rahib","year":"2014","journal-title":"Cancer Res."},{"issue":"2","key":"10.1016\/j.bcp.2020.113857_b0015","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/j.bpg.2005.11.009","article-title":"What's new in pancreatic cancer treatment pipeline?","volume":"20","author":"Von Hoff","year":"2006","journal-title":"Best Pract. Res. Clin. Gastroenterol."},{"issue":"6","key":"10.1016\/j.bcp.2020.113857_b0020","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1038\/nrclinonc.2015.53","article-title":"Pancreatic cancer: from state-of-the-art treatments to promising novel therapies","volume":"12","author":"Garrido-Laguna","year":"2015","journal-title":"Nat. Rev. Clin. Oncol."},{"issue":"8","key":"10.1016\/j.bcp.2020.113857_b0025","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1038\/nm1087","article-title":"Cancer genes and the pathways they control","volume":"10","author":"Vogelstein","year":"2004","journal-title":"Nat. Med."},{"issue":"2","key":"10.1016\/j.bcp.2020.113857_b0030","first-page":"104","article-title":"FOXM1 and its oncogenic signaling in pancreatic cancer pathogenesis","volume":"1845","author":"Huang","year":"2014","journal-title":"BBA"},{"issue":"12","key":"10.1016\/j.bcp.2020.113857_b0035","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1515\/BC.2007.159","article-title":"FOXM1, a typical proliferation-associated transcription factor","volume":"388","author":"Wierstra","year":"2007","journal-title":"Biol. Chem."},{"key":"10.1016\/j.bcp.2020.113857_b0040","doi-asserted-by":"crossref","unstructured":"B. Pandit, M. Halasi, A.L. Gartel, p53 negatively regulates expression of FoxM1, Cell cycle (Georgetown, Tex.) 8(20) (2009) 3425\u20133427.","DOI":"10.4161\/cc.8.20.9628"},{"issue":"1","key":"10.1016\/j.bcp.2020.113857_b0045","first-page":"119","article-title":"The nuclear factor-kappa B RelA transcription factor is constitutively activated in human pancreatic adenocarcinoma cells","volume":"5","author":"Wang","year":"1999","journal-title":"Clin. Cancer Res. : Off. J. Am. Assoc. Cancer Res."},{"issue":"1","key":"10.1016\/j.bcp.2020.113857_b0050","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/S0022-4804(03)00354-8","article-title":"Increased expression of NF-kappa B subunits in human pancreatic cancer cells","volume":"118","author":"Chandler","year":"2004","journal-title":"J. Surg. Res."},{"key":"10.1016\/j.bcp.2020.113857_b0055","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.ceb.2014.09.010","article-title":"ROS-dependent signal transduction","volume":"33","author":"Reczek","year":"2015","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1016\/j.bcp.2020.113857_b0060","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1146\/annurev-cancerbio-041916-065808","article-title":"The two faces of reactive oxygen species in Cancer","volume":"1","author":"Reczek","year":"2017","journal-title":"Ann. Rev. Cancer Biol."},{"issue":"2","key":"10.1016\/j.bcp.2020.113857_b0065","first-page":"273","article-title":"Intracellular zinc increase inhibits p53(-\/-) pancreatic adenocarcinoma cell growth by ROS\/AIF-mediated apoptosis","volume":"1793","author":"Donadelli","year":"2009","journal-title":"BBA"},{"key":"10.1016\/j.bcp.2020.113857_b0070","doi-asserted-by":"crossref","first-page":"1616781","DOI":"10.1155\/2016\/1616781","article-title":"Reactive oxygen species and targeted therapy for pancreatic cancer","volume":"2016","author":"Zhang","year":"2016","journal-title":"Oxid. Med. Cell. Longevity"},{"key":"10.1016\/j.bcp.2020.113857_b0075","doi-asserted-by":"crossref","DOI":"10.1038\/cddis.2011.36","article-title":"Gemcitabine\/cannabinoid combination triggers autophagy in pancreatic cancer cells through a ROS-mediated mechanism","volume":"2","author":"Donadelli","year":"2011","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.bcp.2020.113857_b0080","first-page":"31","article-title":"Anti-inflammatory agents as cancer therapeutics","volume":"57","author":"Kashfi","year":"2009","journal-title":"Adv. Pharmacol. (San Diego Calif.)"},{"issue":"2","key":"10.1016\/j.bcp.2020.113857_b0085","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1053\/gast.2000.9304","article-title":"Nitric oxide in mucosal defense: a little goes a long way","volume":"119","author":"Wallace","year":"2000","journal-title":"Gastroenterology"},{"issue":"2","key":"10.1016\/j.bcp.2020.113857_b0090","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/j.gtc.2009.03.001","article-title":"Prevention of nonsteroidal anti-inflammatory drug-induced ulcer: looking to the future","volume":"38","author":"Fiorucci","year":"2009","journal-title":"Gastroenterol. Clin. North Am."},{"issue":"3","key":"10.1016\/j.bcp.2020.113857_b0095","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1021\/ml300002m","article-title":"NOSH-aspirin: a novel nitric oxide-hydrogen sulfide-releasing hybrid: a new class of anti-inflammatory pharmaceuticals","volume":"3","author":"Kodela","year":"2012","journal-title":"ACS Med. Chem. Lett."},{"issue":"3","key":"10.1016\/j.bcp.2020.113857_b0100","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/j.bbrc.2012.02.051","article-title":"NOSH-aspirin (NBS-1120), a novel nitric oxide- and hydrogen sulfide-releasing hybrid is a potent inhibitor of colon cancer cell growth in vitro and in a xenograft mouse model","volume":"419","author":"Chattopadhyay","year":"2012","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"4","key":"10.1016\/j.bcp.2020.113857_b0105","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1016\/j.bcp.2015.09.014","article-title":"NOSH-aspirin (NBS-1120), a novel nitric oxide- and hydrogen sulfide-releasing hybrid has enhanced chemo-preventive properties compared to aspirin, is gastrointestinal safe with all the classic therapeutic indications","volume":"98","author":"Kodela","year":"2015","journal-title":"Biochem. Pharmacol."},{"issue":"6","key":"10.1016\/j.bcp.2020.113857_b0110","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1016\/j.bcp.2011.12.018","article-title":"Hydrogen sulfide-releasing NSAIDs inhibit the growth of human cancer cells: a general property and evidence of a tissue type-independent effect","volume":"83","author":"Chattopadhyay","year":"2012","journal-title":"Biochem. Pharmacol."},{"issue":"6","key":"10.1016\/j.bcp.2020.113857_b0115","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1016\/j.bcp.2011.12.019","article-title":"Hydrogen sulfide-releasing aspirin suppresses NF-kappaB signaling in estrogen receptor negative breast cancer cells in vitro and in vivo","volume":"83","author":"Chattopadhyay","year":"2012","journal-title":"Biochem. Pharmacol."},{"issue":"5234","key":"10.1016\/j.bcp.2020.113857_b0120","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1126\/science.270.5234.296","article-title":"Requirement for generation of H2O2 for platelet-derived growth factor signal transduction","volume":"270","author":"Sundaresan","year":"1995","journal-title":"Science"},{"issue":"41","key":"10.1016\/j.bcp.2020.113857_b0125","doi-asserted-by":"crossref","first-page":"15038","DOI":"10.1073\/pnas.0601945103","article-title":"Selective fluorescent imaging of superoxide in vivo using ethidium-based probes","volume":"103","author":"Robinson","year":"2006","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"issue":"8","key":"10.1016\/j.bcp.2020.113857_b0130","doi-asserted-by":"crossref","first-page":"4503","DOI":"10.1158\/0008-5472.CAN-05-3118","article-title":"Nitric oxide-donating aspirin prevents pancreatic cancer in a hamster tumor model","volume":"66","author":"Ouyang","year":"2006","journal-title":"Cancer Res."},{"issue":"3","key":"10.1016\/j.bcp.2020.113857_b0135","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1124\/jpet.102.042754","article-title":"Nitric oxide-donating nonsteroidal anti-inflammatory drugs inhibit the growth of various cultured human cancer cells: evidence of a tissue type-independent effect","volume":"303","author":"Kashfi","year":"2002","journal-title":"J. Pharmacol. Exp. Ther."},{"issue":"4","key":"10.1016\/j.bcp.2020.113857_b0140","doi-asserted-by":"crossref","first-page":"1910","DOI":"10.4049\/jimmunol.130.4.1910","article-title":"Flow cytometric studies of oxidative product formation by neutrophils: a graded response to membrane stimulation","volume":"130","author":"Bass","year":"1983","journal-title":"J. Immunol."},{"issue":"2","key":"10.1016\/j.bcp.2020.113857_b0145","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1021\/tx00026a012","article-title":"Evaluation of the probe 2',7'-dichlorofluorescin as an indicator of reactive oxygen species formation and oxidative stress","volume":"5","author":"LeBel","year":"1992","journal-title":"Chem. Res. Toxicol."},{"issue":"6 Pt 2","key":"10.1016\/j.bcp.2020.113857_b0150","article-title":"Generation of superoxide in cardiomyocytes during ischemia before reperfusion","volume":"277","author":"Becker","year":"1999","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.bcp.2020.113857_b0155","doi-asserted-by":"crossref","first-page":"5165","DOI":"10.1038\/ncomms6165","article-title":"Suppression of the FOXM1 transcriptional programme via novel small molecule inhibition","volume":"5","author":"Gormally","year":"2014","journal-title":"Nat. Commun."},{"issue":"12","key":"10.1016\/j.bcp.2020.113857_b0160","doi-asserted-by":"crossref","first-page":"5181","DOI":"10.1158\/0008-5472.CAN-04-4059","article-title":"Loss of the forkhead transcription factor FoxM1 causes centrosome amplification and mitotic catastrophe","volume":"65","author":"Wonsey","year":"2005","journal-title":"Cancer Res."},{"issue":"2","key":"10.1016\/j.bcp.2020.113857_b0165","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1038\/ncb0205-108","article-title":"FoxM1 dances with mitosis","volume":"7","author":"Costa","year":"2005","journal-title":"Nat. Cell Biol."},{"issue":"1","key":"10.1016\/j.bcp.2020.113857_b0170","first-page":"28","article-title":"FOXM1: from cancer initiation to progression and treatment","volume":"1819","author":"Koo","year":"2012","journal-title":"BBA"},{"issue":"2","key":"10.1016\/j.bcp.2020.113857_b0175","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1038\/ncb1217","article-title":"FoxM1 is required for execution of the mitotic programme and chromosome stability","volume":"7","author":"Laoukili","year":"2005","journal-title":"Nat. Cell Biol."},{"issue":"1","key":"10.1016\/j.bcp.2020.113857_b0180","first-page":"92","article-title":"FoxM1: at the crossroads of ageing and cancer","volume":"1775","author":"Laoukili","year":"2007","journal-title":"BBA"},{"issue":"1","key":"10.1016\/j.bcp.2020.113857_b0185","doi-asserted-by":"crossref","first-page":"13","DOI":"10.4132\/jptm.2014.12.26","article-title":"Genomic landscapes of pancreatic neoplasia","volume":"49","author":"Wood","year":"2015","journal-title":"J. Pathol. Transl. Med."},{"issue":"5","key":"10.1016\/j.bcp.2020.113857_b0190","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1007\/s00428-003-0784-4","article-title":"A comprehensive characterization of pancreatic ductal carcinoma cell lines: towards the establishment of an in vitro research platform","volume":"442","author":"Sipos","year":"2003","journal-title":"Virchows Archiv: Int. J. Pathol."},{"issue":"1","key":"10.1016\/j.bcp.2020.113857_b0195","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.bbrc.2004.11.009","article-title":"NO-donating aspirin inhibits the growth of leukemic Jurkat cells and modulates beta-catenin expression","volume":"326","author":"Nath","year":"2005","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"10","key":"10.1016\/j.bcp.2020.113857_b0200","doi-asserted-by":"crossref","first-page":"1302","DOI":"10.1016\/j.leukres.2013.07.004","article-title":"Hydrogen sulfide-releasing aspirin inhibits the growth of leukemic Jurkat cells and modulates beta-catenin expression","volume":"37","author":"Chattopadhyay","year":"2013","journal-title":"Leuk. Res."},{"key":"10.1016\/j.bcp.2020.113857_b0205","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.ejps.2013.11.009","article-title":"ROS and RNS induced apoptosis through p53 and iNOS mediated pathway by a dibasic hydroxamic acid molecule in leukemia cells","volume":"52","author":"Banerjee","year":"2014","journal-title":"Eur. J. Pharmaceutical Sci.: Off. J. Eur. Feder. Pharmaceutical Sci."},{"issue":"1","key":"10.1016\/j.bcp.2020.113857_b0210","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1385\/IJGC:29:1:37","article-title":"A novel, clinically relevant animal model of metastatic pancreatic adenocarcinoma biology and therapy","volume":"29","author":"Wang","year":"2001","journal-title":"Int. J. Pancreatol.: Off. J. Int. Assoc. Pancreatol."},{"issue":"33","key":"10.1016\/j.bcp.2020.113857_b0215","doi-asserted-by":"crossref","first-page":"52993","DOI":"10.18632\/oncotarget.10323","article-title":"Inducible nitric oxide synthase enhances disease aggressiveness in pancreatic cancer","volume":"7","author":"Wang","year":"2016","journal-title":"Oncotarget"},{"issue":"8","key":"10.1016\/j.bcp.2020.113857_b0220","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.1158\/1541-7786.MCR-09-0472","article-title":"Nitric oxide inhibits the proliferation and invasion of pancreatic cancer cells through degradation of insulin receptor substrate-1 protein","volume":"8","author":"Sugita","year":"2010","journal-title":"Mol. Cancer research : MCR"},{"issue":"4","key":"10.1016\/j.bcp.2020.113857_b0225","doi-asserted-by":"crossref","first-page":"421","DOI":"10.2174\/138161210790232194","article-title":"Nitric oxide and pancreatic cancer pathogenesis, prevention, and treatment","volume":"16","author":"Wang","year":"2010","journal-title":"Curr. Pharm. Des."},{"key":"10.1016\/j.bcp.2020.113857_b0230","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/j.redox.2015.08.009","article-title":"The dual role of iNOS in cancer","volume":"6","author":"Vannini","year":"2015","journal-title":"Redox Biol."},{"issue":"6","key":"10.1016\/j.bcp.2020.113857_b0235","doi-asserted-by":"crossref","first-page":"9354","DOI":"10.18632\/oncotarget.14069","article-title":"Prognostic value and clinicopathological features of PD-1\/PD-L1 expression with mismatch repair status and desmoplastic stroma in Chinese patients with pancreatic cancer","volume":"8","author":"Wang","year":"2017","journal-title":"Oncotarget"},{"issue":"17","key":"10.1016\/j.bcp.2020.113857_b0245","doi-asserted-by":"crossref","first-page":"8293","DOI":"10.1158\/0008-5472.CAN-07-1265","article-title":"Down-regulation of Forkhead Box M1 transcription factor leads to the inhibition of invasion and angiogenesis of pancreatic cancer cells","volume":"67","author":"Wang","year":"2007","journal-title":"Cancer Res."},{"issue":"48","key":"10.1016\/j.bcp.2020.113857_b0250","doi-asserted-by":"crossref","first-page":"4295","DOI":"10.1038\/onc.2009.282","article-title":"Pro-proliferative FoxM1 is a target of p53-mediated repression","volume":"28","author":"Barsotti","year":"2009","journal-title":"Oncogene"},{"issue":"35","key":"10.1016\/j.bcp.2020.113857_b0255","doi-asserted-by":"crossref","first-page":"25134","DOI":"10.1074\/jbc.M513901200","article-title":"Identification of cell cycle regulatory genes as principal targets of p53-mediated transcriptional repression","volume":"281","author":"Spurgers","year":"2006","journal-title":"J. Biol. Chem."},{"issue":"3","key":"10.1016\/j.bcp.2020.113857_b0260","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/j.ccr.2012.08.001","article-title":"EGF receptor signaling is essential for k-ras oncogene-driven pancreatic ductal adenocarcinoma","volume":"22","author":"Navas","year":"2012","journal-title":"Cancer Cell"},{"issue":"6","key":"10.1016\/j.bcp.2020.113857_b0265","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.1083\/jcb.141.6.1423","article-title":"The regulation of reactive oxygen species production during programmed cell death","volume":"141","author":"Tan","year":"1998","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.bcp.2020.113857_b0270","doi-asserted-by":"crossref","unstructured":"D.E. Nesbitt, M. Chattopadhyay, F. Vannini, T.-T. LeCao, C., R. Kodela, N. Nath, K. Kashfi, NOSH-aspirin inhibits breast cancer cell growth: an effect modulated through reactive oxygen species and independent of the ER status., Proceedings of the 104th Annual Meeting of the American Association for Cancer Research; 2013 Apr 6-10; Washington, DC. Philadelphia (PA): AACR; Cancer Res 2013;73 (8 Suppl):Abstract nr 4793. doi:10.1158\/1538-7445.AM2013-4793, Washington, DC, 2013, Apr 6\u201310.","DOI":"10.1158\/1538-7445.AM2013-4793"},{"issue":"7","key":"10.1016\/j.bcp.2020.113857_b0275","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1016\/j.bcp.2005.05.004","article-title":"Non-COX-2 targets and cancer: expanding the molecular target repertoire of chemoprevention","volume":"70","author":"Kashfi","year":"2005","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.bcp.2020.113857_b0280","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.niox.2014.12.009","article-title":"On the chemical biology of the nitrite\/sulfide interaction","volume":"46","author":"Cortese-Krott","year":"2015","journal-title":"Nitric Oxide: Biol. Chem."},{"issue":"29","key":"10.1016\/j.bcp.2020.113857_b0285","doi-asserted-by":"crossref","first-page":"12016","DOI":"10.1021\/ja3009693","article-title":"Chemical characterization of the smallest S-nitrosothiol, HSNO; cellular cross-talk of H2S and S-nitrosothiols","volume":"134","author":"Filipovic","year":"2012","journal-title":"J. Am. Chem. Soc."},{"issue":"34","key":"10.1016\/j.bcp.2020.113857_b0290","doi-asserted-by":"crossref","first-page":"E4651","DOI":"10.1073\/pnas.1509277112","article-title":"Key bioactive reaction products of the NO\/H2S interaction are S\/N-hybrid species, polysulfides, and nitroxyl","volume":"112","author":"Cortese-Krott","year":"2015","journal-title":"Proc. Natl. Acad. Sci. U.S.A"}],"container-title":["Biochemical Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000629522030085X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000629522030085X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T13:11:44Z","timestamp":1757769104000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S000629522030085X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6]]},"references-count":57,"alternative-id":["S000629522030085X"],"URL":"https:\/\/doi.org\/10.1016\/j.bcp.2020.113857","relation":{},"ISSN":["0006-2952"],"issn-type":[{"value":"0006-2952","type":"print"}],"subject":[],"published":{"date-parts":[[2020,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"NOSH-aspirin (NBS-1120) inhibits pancreatic cancer cell growth in a xenograft mouse model: Modulation of FoxM1, p53, NF-\u03baB, iNOS, caspase-3 and ROS","name":"articletitle","label":"Article Title"},{"value":"Biochemical Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bcp.2020.113857","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"113857"}}