{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T12:44:31Z","timestamp":1790685871945,"version":"4.1.0"},"reference-count":71,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100004396","name":"Thailand Research Fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004396","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004704","name":"National Research Council of Thailand","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004704","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002842","name":"Chiang Mai University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002842","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100017170","name":"Thailand Science Research and Innovation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100017170","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004192","name":"National Science and Technology Development Agency","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004192","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical Pharmacology"],"published-print":{"date-parts":[[2020,12]]},"DOI":"10.1016\/j.bcp.2020.114295","type":"journal-article","created":{"date-parts":[[2020,10,17]],"date-time":"2020-10-17T19:24:39Z","timestamp":1602962679000},"page":"114295","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":40,"special_numbering":"C","title":["Pharmacological inhibition of mitochondrial fission attenuates cardiac ischemia-reperfusion injury in pre-diabetic rats"],"prefix":"10.1016","volume":"182","author":[{"given":"Chayodom","family":"Maneechote","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siripong","family":"Palee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sasiwan","family":"Kerdphoo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thidarat","family":"Jaiwongkam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siriporn C.","family":"Chattipakorn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nipon","family":"Chattipakorn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"7","key":"10.1016\/j.bcp.2020.114295_b0005","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1007\/s40273-014-0243-x","article-title":"The epidemiology of obesity: a big picture","volume":"33","author":"Hruby","year":"2015","journal-title":"Pharmacoeconomics"},{"key":"10.1016\/j.bcp.2020.114295_b0010","first-page":"15","article-title":"Pathogenesis of coronary artery disease: focus on genetic risk factors and identification of genetic variants","volume":"7","author":"Sayols-Baixeras","year":"2014","journal-title":"Appl. Clin. Genet."},{"issue":"16","key":"10.1016\/j.bcp.2020.114295_b0015","doi-asserted-by":"crossref","DOI":"10.3390\/ijms20163972","article-title":"Targeting mitochondrial fission using Mdivi-1 in a clinically relevant large animal model of acute myocardial infarction: a pilot study","volume":"20","author":"Ong","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.bcp.2020.114295_b0020","doi-asserted-by":"crossref","first-page":"08","DOI":"10.12703\/P7-08","article-title":"Pathophysiology of coronary artery disease leading to acute coronary syndromes","volume":"7","author":"Ambrose","year":"2015","journal-title":"F1000Prime Rep"},{"issue":"24","key":"10.1016\/j.bcp.2020.114295_b0025","doi-asserted-by":"crossref","first-page":"2431","DOI":"10.1042\/CS20190960","article-title":"Mitochondrial dynamic modulation exerts cardiometabolic protection in obese insulin-resistant rats","volume":"133","author":"Maneechote","year":"2019","journal-title":"Clin. Sci. (Lond.)"},{"issue":"13","key":"10.1016\/j.bcp.2020.114295_b0030","first-page":"935","article-title":"Targeting reperfusion injury in patients with ST-segment elevation myocardial infarction: trials and tribulations","volume":"38","author":"Hausenloy","year":"2017","journal-title":"Eur. Heart J."},{"issue":"6","key":"10.1016\/j.bcp.2020.114295_b0035","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1007\/s00395-016-0588-8","article-title":"Ischaemic conditioning and targeting reperfusion injury: a 30 year voyage of discovery","volume":"111","author":"Hausenloy","year":"2016","journal-title":"Basic Res. Cardiol."},{"issue":"1","key":"10.1016\/j.bcp.2020.114295_b0040","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.jacc.2018.09.086","article-title":"Multitarget strategies to reduce myocardial ischemia\/reperfusion injury: JACC review topic of the week","volume":"73","author":"Davidson","year":"2019","journal-title":"J. Am. Coll. Cardiol."},{"issue":"11","key":"10.1016\/j.bcp.2020.114295_b0045","doi-asserted-by":"crossref","first-page":"2643","DOI":"10.1111\/jcmm.13330","article-title":"Roles of mitochondrial dynamics modulators in cardiac ischaemia\/reperfusion injury","volume":"21","author":"Maneechote","year":"2017","journal-title":"J. Cell Mol. Med."},{"key":"10.1016\/j.bcp.2020.114295_b0050","doi-asserted-by":"crossref","DOI":"10.1016\/j.mito.2019.06.002","article-title":"Mitochondrial dynamics and their potential as a therapeutic target","author":"Whitley","year":"2019","journal-title":"Mitochondrion"},{"key":"10.1016\/j.bcp.2020.114295_b0055","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1007\/978-1-4614-3573-0_2","article-title":"Mitochondrial dynamics: the intersection of form and function","volume":"748","author":"Ferree","year":"2012","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.bcp.2020.114295_b0060","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.41351","article-title":"Mitochondrial fusion supports increased oxidative phosphorylation during cell proliferation","volume":"8","author":"Yao","year":"2019","journal-title":"Elife"},{"issue":"8","key":"10.1016\/j.bcp.2020.114295_b0065","doi-asserted-by":"crossref","first-page":"1890","DOI":"10.1111\/bph.12516","article-title":"Mitochondrial fusion and fission proteins: novel therapeutic targets for combating cardiovascular disease","volume":"171","author":"Hall","year":"2014","journal-title":"Br. J. Pharmacol."},{"issue":"15","key":"10.1016\/j.bcp.2020.114295_b0070","doi-asserted-by":"crossref","first-page":"1669","DOI":"10.1042\/CS20180510","article-title":"Differential temporal inhibition of mitochondrial fission by Mdivi-1 exerts effective cardioprotection in cardiac ischemia\/reperfusion injury","volume":"132","author":"Maneechote","year":"2018","journal-title":"Clin. Sci. (Lond.)"},{"issue":"18","key":"10.1016\/j.bcp.2020.114295_b0075","doi-asserted-by":"crossref","first-page":"2012","DOI":"10.1161\/CIRCULATIONAHA.109.906610","article-title":"Inhibiting mitochondrial fission protects the heart against ischemia\/reperfusion injury","volume":"121","author":"Ong","year":"2010","journal-title":"Circulation"},{"key":"10.1016\/j.bcp.2020.114295_b0080","doi-asserted-by":"crossref","first-page":"570","DOI":"10.3389\/fendo.2019.00570","article-title":"Dysregulated mitochondrial dynamics and metabolism in obesity, diabetes, and cancer","volume":"10","author":"Dai","year":"2019","journal-title":"Front. Endocrinol. (Lausanne)"},{"issue":"1","key":"10.1016\/j.bcp.2020.114295_b0085","article-title":"Reactive oxygen species and mitochondrial dynamics: the yin and yang of mitochondrial dysfunction and cancer progression","volume":"7","author":"Je\u017eek","year":"2018","journal-title":"Antioxidants (Basel)"},{"issue":"1","key":"10.1016\/j.bcp.2020.114295_b0090","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1186\/s12933-017-0501-2","article-title":"Inhibition of dynamin-related protein 1 protects against myocardial ischemia-reperfusion injury in diabetic mice","volume":"16","author":"Ding","year":"2017","journal-title":"Cardiovasc. Diabetol."},{"key":"10.1016\/j.bcp.2020.114295_b0095","doi-asserted-by":"crossref","first-page":"7514383","DOI":"10.1155\/2018\/7514383","article-title":"The causal role of mitochondrial dynamics in regulating insulin resistance in diabetes: link through mitochondrial reactive oxygen species","volume":"2018","author":"Lin","year":"2018","journal-title":"Oxid. Med. Cell. Longev."},{"issue":"2","key":"10.1016\/j.bcp.2020.114295_b0100","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1128\/MCB.05603-11","article-title":"Mitochondrial fission contributes to mitochondrial dysfunction and insulin resistance in skeletal muscle","volume":"32","author":"Jheng","year":"2012","journal-title":"Mol. Cell. Biol."},{"issue":"10","key":"10.1016\/j.bcp.2020.114295_b0105","doi-asserted-by":"crossref","first-page":"2301","DOI":"10.1016\/j.celrep.2017.02.035","article-title":"Dynamin-related protein 1-dependent mitochondrial fission changes in the dorsal vagal complex regulate insulin action","volume":"18","author":"Filippi","year":"2017","journal-title":"Cell Rep."},{"issue":"2","key":"10.1016\/j.bcp.2020.114295_b0110","doi-asserted-by":"crossref","DOI":"10.1111\/jpi.12491","article-title":"Melatonin prevents Drp1-mediated mitochondrial fission in diabetic hearts through SIRT1-PGC1alpha pathway","volume":"65","author":"Ding","year":"2018","journal-title":"J. Pineal Res."},{"issue":"2","key":"10.1016\/j.bcp.2020.114295_b0115","doi-asserted-by":"crossref","first-page":"e38","DOI":"10.1097\/CCM.0000000000000817","article-title":"Inhibition of the mitochondrial fission protein dynamin-related protein 1 improves survival in a murine cardiac arrest model","volume":"43","author":"Sharp","year":"2015","journal-title":"Crit. Care Med."},{"issue":"1","key":"10.1016\/j.bcp.2020.114295_b0120","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1096\/fj.12-226225","article-title":"Dynamin-related protein 1 (Drp1)-mediated diastolic dysfunction in myocardial ischemia-reperfusion injury: therapeutic benefits of Drp1 inhibition to reduce mitochondrial fission","volume":"28","author":"Sharp","year":"2014","journal-title":"FASEB J."},{"issue":"5","key":"10.1016\/j.bcp.2020.114295_b0125","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.113.000461","article-title":"Acute inhibition of excessive mitochondrial fission after myocardial infarction prevents long-term cardiac dysfunction","volume":"2","author":"Disatnik","year":"2013","journal-title":"J. Am. Heart Assoc."},{"issue":"5","key":"10.1016\/j.bcp.2020.114295_b0130","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1007\/s00395-016-0578-x","article-title":"Inhibition of mitochondrial fission as a molecular target for cardioprotection: critical importance of the timing of treatment","volume":"111","author":"Dong","year":"2016","journal-title":"Basic Res. Cardiol."},{"issue":"1","key":"10.1016\/j.bcp.2020.114295_b0135","doi-asserted-by":"crossref","first-page":"193","DOI":"10.2337\/db16-0915","article-title":"Metformin suppresses diabetes-accelerated atherosclerosis via the inhibition of Drp1-mediated mitochondrial fission","volume":"66","author":"Wang","year":"2017","journal-title":"Diabetes"},{"issue":"3","key":"10.1016\/j.bcp.2020.114295_b0140","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0032388","article-title":"Mitochondrial division\/mitophagy inhibitor (Mdivi) ameliorates pressure overload induced heart failure","volume":"7","author":"Givvimani","year":"2012","journal-title":"PLoS One"},{"issue":"15","key":"10.1016\/j.bcp.2020.114295_b0145","doi-asserted-by":"crossref","first-page":"5969","DOI":"10.1073\/pnas.1213294110","article-title":"Pim-1 preserves mitochondrial morphology by inhibiting dynamin-related protein 1 translocation","volume":"110","author":"Din","year":"2013","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"issue":"3","key":"10.1016\/j.bcp.2020.114295_b0150","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1042\/CS20190014","article-title":"Balancing mitochondrial dynamics via increasing mitochondrial fusion attenuates infarct size and left ventricular dysfunction in rats with cardiac ischemia\/reperfusion injury","volume":"133","author":"Maneechote","year":"2019","journal-title":"Clin. Sci. (Lond.)"},{"issue":"1","key":"10.1016\/j.bcp.2020.114295_b0155","doi-asserted-by":"crossref","first-page":"R11","DOI":"10.1530\/JME-12-0203","article-title":"The emerging role of the mitochondrial-derived peptide humanin in stress resistance","volume":"50","author":"Yen","year":"2013","journal-title":"J. Mol. Endocrinol."},{"issue":"2","key":"10.1016\/j.bcp.2020.114295_b0160","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1007\/s11357-015-9766-0","article-title":"Obese-insulin resistance accelerates and aggravates cardiometabolic disorders and cardiac mitochondrial dysfunction in estrogen-deprived female rats","volume":"37","author":"Sivasinprasasn","year":"2015","journal-title":"Age (Dordrecht, Netherlands)"},{"issue":"19\u201320","key":"10.1016\/j.bcp.2020.114295_b0165","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1016\/j.lfs.2011.08.011","article-title":"Effects of estrogen in preventing neuronal insulin resistance in hippocampus of obese rats are different between genders","volume":"89","author":"Pratchayasakul","year":"2011","journal-title":"Life Sci."},{"key":"10.1016\/j.bcp.2020.114295_b0170","article-title":"Chronic treatment with prebiotics, probiotics and synbiotics attenuated cardiac dysfunction by improving cardiac mitochondrial dysfunction in male obese insulin-resistant rats","author":"Tunapong","year":"2017","journal-title":"Eur. J. Nutr."},{"issue":"8","key":"10.1016\/j.bcp.2020.114295_b0175","doi-asserted-by":"crossref","first-page":"1847","DOI":"10.1111\/jcmm.12556","article-title":"High-fat diet induces cardiac remodelling and dysfunction: assessment of the role played by SIRT3 loss","volume":"19","author":"Zeng","year":"2015","journal-title":"J. Cell Mol. Med."},{"key":"10.1016\/j.bcp.2020.114295_b0180","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.mad.2016.12.005","article-title":"Mitochondrial activity and dynamics changes regarding metabolism in ageing and obesity","volume":"162","author":"L\u00f3pez-Lluch","year":"2017","journal-title":"Mech. Ageing Dev."},{"issue":"6","key":"10.1016\/j.bcp.2020.114295_b0185","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1161\/01.CIR.0000083716.82622.FD","article-title":"Disruption of leptin signaling contributes to cardiac hypertrophy independently of body weight in mice","volume":"108","author":"Barouch Lili","year":"2003","journal-title":"Circulation"},{"issue":"5","key":"10.1016\/j.bcp.2020.114295_b0190","first-page":"479","article-title":"High-fat diet promotes cardiac remodeling in an experimental model of obesity","volume":"105","author":"Martins","year":"2015","journal-title":"Arq. Bras. Cardiol."},{"issue":"12","key":"10.1016\/j.bcp.2020.114295_b0195","doi-asserted-by":"crossref","first-page":"1384","DOI":"10.1038\/nm1137","article-title":"Adiponectin-mediated modulation of hypertrophic signals in the heart","volume":"10","author":"Shibata","year":"2004","journal-title":"Nat. Med."},{"issue":"1","key":"10.1016\/j.bcp.2020.114295_b0200","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1161\/01.HYP.0000151325.83008.b4","article-title":"Obesity-associated hypertension","volume":"45","author":"Rahmouni","year":"2005","journal-title":"Hypertension"},{"key":"10.1016\/j.bcp.2020.114295_b0205","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1016\/j.redox.2017.01.013","article-title":"Mitochondrial dynamics in type 2 diabetes: pathophysiological implications","volume":"11","author":"Rovira-Llopis","year":"2017","journal-title":"Redox Biol."},{"issue":"3","key":"10.1016\/j.bcp.2020.114295_b0210","first-page":"151","article-title":"Mitochondrial dynamics and mitochondrial dysfunction in diabetes","volume":"70","author":"Wada","year":"2016","journal-title":"Acta Med. Okayama"},{"issue":"10","key":"10.1016\/j.bcp.2020.114295_b0215","doi-asserted-by":"crossref","first-page":"1846","DOI":"10.1016\/j.biocel.2009.02.004","article-title":"Role of mitochondrial dynamics proteins in the pathophysiology of obesity and type 2 diabetes","volume":"41","author":"Zorzano","year":"2009","journal-title":"Int. J. Biochem. Cell Biol."},{"issue":"5","key":"10.1016\/j.bcp.2020.114295_b0220","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1172\/JCI37829","article-title":"Regulation of mitochondrial dynamics in acute kidney injury in cell culture and rodent models","volume":"119","author":"Brooks","year":"2009","journal-title":"J. Clin. Invest."},{"issue":"9","key":"10.1016\/j.bcp.2020.114295_b0225","doi-asserted-by":"crossref","first-page":"2733","DOI":"10.1681\/ASN.2015101096","article-title":"Dynamin-related protein 1 deficiency improves mitochondrial fitness and protects against progression of diabetic nephropathy","volume":"27","author":"Ayanga","year":"2016","journal-title":"J. Am. Soc. Nephrol."},{"issue":"6","key":"10.1016\/j.bcp.2020.114295_b0230","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1016\/j.jstrokecerebrovasdis.2013.12.021","article-title":"Mdivi-1 prevents apoptosis induced by ischemia-reperfusion injury in primary hippocampal cells via inhibition of reactive oxygen species-activated mitochondrial pathway","volume":"23","author":"Wang","year":"2014","journal-title":"J. Stroke Cerebrovasc. Dis."},{"issue":"10","key":"10.1016\/j.bcp.2020.114295_b0235","doi-asserted-by":"crossref","first-page":"1665","DOI":"10.1111\/bph.13468","article-title":"Drp-1, a potential therapeutic target for brain ischaemic stroke","volume":"173","author":"Zuo","year":"2016","journal-title":"Br. J. Pharmacol."},{"issue":"6","key":"10.1016\/j.bcp.2020.114295_b0240","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1111\/cns.12266","article-title":"Amelioration of ischemic mitochondrial injury and Bax-dependent outer membrane permeabilization by Mdivi-1","volume":"20","author":"Zhao","year":"2014","journal-title":"CNS Neurosci. Ther."},{"key":"10.1016\/j.bcp.2020.114295_b0245","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.brainres.2019.01.018","article-title":"Dephosphorylation by calcineurin regulates translocation of dynamin-related protein 1 to mitochondria in hepatic ischemia reperfusion induced hippocampus injury in young mice","volume":"1711","author":"Yu","year":"2019","journal-title":"Brain Res."},{"key":"10.1016\/j.bcp.2020.114295_b0250","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.cbi.2019.03.013","article-title":"Inhibition of Drp1 after traumatic brain injury provides brain protection and improves behavioral performance in rats","volume":"304","author":"Song","year":"2019","journal-title":"Chem. Biol. Interact."},{"issue":"6","key":"10.1016\/j.bcp.2020.114295_b0255","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1038\/s41418-018-0086-7","article-title":"Pathogenesis of cardiac ischemia reperfusion injury is associated with CK2alpha-disturbed mitochondrial homeostasis via suppression of FUNDC1-related mitophagy","volume":"25","author":"Zhou","year":"2018","journal-title":"Cell Death Differ."},{"issue":"10","key":"10.1016\/j.bcp.2020.114295_b0260","doi-asserted-by":"crossref","first-page":"1528","DOI":"10.1007\/PL00000793","article-title":"Effects of myocardial ischemia and reperfusion on mitochondrial function and susceptibility to oxidative stress","volume":"58","author":"Venditti","year":"2001","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.bcp.2020.114295_b0265","doi-asserted-by":"crossref","first-page":"109","DOI":"10.3389\/fphys.2015.00109","article-title":"Diet impact on mitochondrial bioenergetics and dynamics","volume":"6","author":"Putti","year":"2015","journal-title":"Front. Physiol."},{"issue":"1","key":"10.1016\/j.bcp.2020.114295_b0270","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.molcel.2014.10.028","article-title":"Mitochondrial shape governs BAX-induced membrane permeabilization and apoptosis","volume":"57","author":"Renault","year":"2015","journal-title":"Mol. Cell"},{"issue":"2","key":"10.1016\/j.bcp.2020.114295_b0275","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.ymeth.2013.03.030","article-title":"BAK\/BAX activation and cytochrome c release assays using isolated mitochondria","volume":"61","author":"Renault","year":"2013","journal-title":"Methods"},{"issue":"4","key":"10.1016\/j.bcp.2020.114295_b0280","first-page":"540","article-title":"Mitochondrial outer membrane permeabilization during apoptosis: the role of mitochondrial fission","volume":"1813","author":"Landes","year":"2011","journal-title":"BBA"},{"issue":"3","key":"10.1016\/j.bcp.2020.114295_b0285","first-page":"1125","article-title":"Hypoxiainduced mitochondrial translocation of DNM1L increases mitochondrial fission and triggers mPTP opening in HCC cells via activation of HK2","volume":"42","author":"Cai","year":"2019","journal-title":"Oncol. Rep."},{"key":"10.1016\/j.bcp.2020.114295_b0290","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.abb.2019.03.016","article-title":"Dynamics of the mitochondrial permeability transition pore: transient and permanent opening events","volume":"666","author":"Boyman","year":"2019","journal-title":"Arch. Biochem. Biophys."},{"issue":"7","key":"10.1016\/j.bcp.2020.114295_b0295","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1083\/jcb.149.7.1503","article-title":"Phosphorylation of connexin43 on serine368 by protein kinase C regulates gap junctional communication","volume":"149","author":"Lampe","year":"2000","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.bcp.2020.114295_b0300","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1007\/978-0-387-09794-7_8","article-title":"Mitochondrial oscillations in physiology and pathophysiology","volume":"641","author":"Aon","year":"2008","journal-title":"Adv. Exp. Med. Biol."},{"issue":"5","key":"10.1016\/j.bcp.2020.114295_b0305","doi-asserted-by":"crossref","first-page":"H1907","DOI":"10.1152\/ajpheart.01242.2010","article-title":"Cholesterol diet leads to attenuation of ischemic preconditioning-induced cardiac protection: the role of connexin 43","volume":"300","author":"Gorbe","year":"2011","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"issue":"1","key":"10.1016\/j.bcp.2020.114295_b0310","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1007\/s12035-014-9002-4","article-title":"Mdivi-1 protects against ischemic brain injury via elevating extracellular adenosine in a cAMP\/CREB-CD39-dependent manner","volume":"53","author":"Cui","year":"2016","journal-title":"Mol. Neurobiol."},{"issue":"1\u20133","key":"10.1016\/j.bcp.2020.114295_b0315","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ejphar.2012.02.012","article-title":"The actions of mdivi-1, an inhibitor of mitochondrial fission, on rapidly activating delayed-rectifier K+ current and membrane potential in HL-1 murine atrial cardiomyocytes","volume":"683","author":"So","year":"2012","journal-title":"Eur. J. Pharmacol."},{"issue":"11","key":"10.1016\/j.bcp.2020.114295_b0320","doi-asserted-by":"crossref","first-page":"7310","DOI":"10.1111\/jcmm.14586","article-title":"PCSK9 inhibitor improves cardiac function and reduces infarct size in rats with ischaemia\/reperfusion injury: benefits beyond lipid-lowering effects","volume":"23","author":"Palee","year":"2019","journal-title":"J. Cell Mol. Med."},{"issue":"6","key":"10.1016\/j.bcp.2020.114295_b0325","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1111\/1755-5922.12210","article-title":"Humanin exerts cardioprotection against cardiac ischemia\/reperfusion injury through attenuation of mitochondrial dysfunction","volume":"34","author":"Thummasorn","year":"2016","journal-title":"Cardiovasc. Ther."},{"issue":"1","key":"10.1016\/j.bcp.2020.114295_b0330","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1093\/cvr\/cvq237","article-title":"Mitochondrial morphology and cardiovascular disease","volume":"88","author":"Ong","year":"2010","journal-title":"Cardiovasc. Res."},{"issue":"2","key":"10.1016\/j.bcp.2020.114295_b0335","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1093\/cvr\/cvr312","article-title":"New roles for mitochondria in cell death in the reperfused myocardium","volume":"94","author":"Ong","year":"2012","journal-title":"Cardiovasc. Res."},{"issue":"5\u20136","key":"10.1016\/j.bcp.2020.114295_b0340","first-page":"518","article-title":"Effect of oxidative stress on dynamics of mitochondrial reticulum","volume":"1757","author":"Pletjushkina","year":"2006","journal-title":"BBA"},{"issue":"6","key":"10.1016\/j.bcp.2020.114295_b0345","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1016\/j.devcel.2017.02.020","article-title":"The putative Drp1 inhibitor mdivi-1 is a reversible mitochondrial complex I inhibitor that modulates reactive oxygen species","volume":"40","author":"Bordt","year":"2017","journal-title":"Dev. Cell"},{"issue":"2","key":"10.1016\/j.bcp.2020.114295_b0350","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/j.expneurol.2009.05.010","article-title":"Drp1 levels constitutively regulate mitochondrial dynamics and cell survival in cortical neurons","volume":"218","author":"Uo","year":"2009","journal-title":"Exp. Neurol."},{"issue":"4","key":"10.1016\/j.bcp.2020.114295_b0355","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1083\/jcb.201110034","article-title":"Mitochondrial division ensures the survival of postmitotic neurons by suppressing oxidative damage","volume":"197","author":"Kageyama","year":"2012","journal-title":"J. Cell Biol."}],"container-title":["Biochemical Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006295220305311?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006295220305311?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T15:05:59Z","timestamp":1762095959000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006295220305311"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12]]},"references-count":71,"alternative-id":["S0006295220305311"],"URL":"https:\/\/doi.org\/10.1016\/j.bcp.2020.114295","relation":{},"ISSN":["0006-2952"],"issn-type":[{"value":"0006-2952","type":"print"}],"subject":[],"published":{"date-parts":[[2020,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Pharmacological inhibition of mitochondrial fission attenuates cardiac ischemia-reperfusion injury in pre-diabetic rats","name":"articletitle","label":"Article Title"},{"value":"Biochemical Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bcp.2020.114295","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"114295"}}