{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T08:31:30Z","timestamp":1788251490630,"version":"build-2803163510"},"reference-count":286,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical Pharmacology"],"published-print":{"date-parts":[[2022,8]]},"DOI":"10.1016\/j.bcp.2022.115122","type":"journal-article","created":{"date-parts":[[2022,6,6]],"date-time":"2022-06-06T20:00:12Z","timestamp":1654545612000},"page":"115122","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":54,"special_numbering":"C","title":["NO, CO and H2S: A trinacrium of bioactive gases in the brain"],"prefix":"10.1016","volume":"202","author":[{"given":"Rosalba","family":"Siracusa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanessa A.","family":"Voltarelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela Trovato","family":"Salinaro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio","family":"Modafferi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salvatore","family":"Cuzzocrea","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward J.","family":"Calabrese","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosanna","family":"Di Paola","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leo E.","family":"Otterbein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vittorio","family":"Calabrese","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.bcp.2022.115122_b0005","doi-asserted-by":"crossref","first-page":"1928","DOI":"10.1016\/0016-5085(92)91454-C","article-title":"Role of nitric oxide in gastrointestinal and hepatic function and disease","volume":"103","author":"Stark","year":"1992","journal-title":"Gastroenterology"},{"issue":"2","key":"10.1016\/j.bcp.2022.115122_b0010","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/0016-5085(93)90407-4","article-title":"Nitric oxide mediates inhibitory nerve input in human and canine jejunum","volume":"104","author":"Stark","year":"1993","journal-title":"Gastroenterology"},{"issue":"3","key":"10.1016\/j.bcp.2022.115122_b0015","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1254\/jjp.64.225","article-title":"Involvement of carbon monoxide in long-term potentiation in the dentate gyrus of anesthetized rats","volume":"64","author":"Ikegaya","year":"1994","journal-title":"Jpn. J. Pharmacol."},{"issue":"5093","key":"10.1016\/j.bcp.2022.115122_b0020","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1126\/science.7678352","article-title":"Carbon monoxide: a putative neural messenger","volume":"259","author":"Verma","year":"1993","journal-title":"Science"},{"issue":"14","key":"10.1016\/j.bcp.2022.115122_b0025","doi-asserted-by":"crossref","first-page":"8567","DOI":"10.1073\/pnas.1431233100","article-title":"A major role for carbon monoxide as an endogenous hyperpolarizing factor in the gastrointestinal tract","volume":"100","author":"Farrugia","year":"2003","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"issue":"2","key":"10.1016\/j.bcp.2022.115122_b0030","doi-asserted-by":"crossref","DOI":"10.1152\/ajpgi.00037.2007","article-title":"Membrane potential gradient is carbon monoxide-dependent in mouse and human small intestine","volume":"293","author":"Sha","year":"2007","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"issue":"1","key":"10.1016\/j.bcp.2022.115122_b0035","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1165\/ajrcmb.27.1.4862","article-title":"Heme oxygenase-1: the \u201cemerging molecule\u201d has arrived","volume":"27","author":"Morse","year":"2002","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"issue":"Suppl 1","key":"10.1016\/j.bcp.2022.115122_b0040","doi-asserted-by":"crossref","first-page":"L41","DOI":"10.1186\/2193-1801-4-S1-L41","article-title":"Anti-inflammatory activities of carbon monoxide-releasing molecules (CO-RMs) in the brain","volume":"4","author":"Motterlini","year":"2015","journal-title":"Springerplus"},{"key":"10.1016\/j.bcp.2022.115122_b0045","doi-asserted-by":"crossref","first-page":"19592","DOI":"10.1038\/srep19592","article-title":"Heme oxygenase-1 is dispensable for the anti-inflammatory activity of intravenous immunoglobulin","volume":"6","author":"Galeotti","year":"2016","journal-title":"Sci. Rep."},{"issue":"29","key":"10.1016\/j.bcp.2022.115122_b0050","doi-asserted-by":"crossref","first-page":"24754","DOI":"10.1074\/jbc.M112.357012","article-title":"Carbon monoxide mediates the anti-apoptotic effects of heme oxygenase-1 in medulloblastoma DAOY cells via K+ channel inhibition","volume":"287","author":"Al-Owais","year":"2012","journal-title":"J. Biol. Chem."},{"issue":"2","key":"10.1016\/j.bcp.2022.115122_b0055","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1038\/nm817","article-title":"Carbon monoxide suppresses arteriosclerotic lesions associated with chronic graft rejection and with balloon injury","volume":"9","author":"Otterbein","year":"2003","journal-title":"Nat. Med."},{"issue":"11","key":"10.1016\/j.bcp.2022.115122_b0060","doi-asserted-by":"crossref","first-page":"4926","DOI":"10.1172\/JCI72853","article-title":"Macrophages sense and kill bacteria through carbon monoxide-dependent inflammasome activation","volume":"124","author":"Wegiel","year":"2014","journal-title":"J. Clin. Invest."},{"issue":"1","key":"10.1016\/j.bcp.2022.115122_b0065","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1111\/imm.12124","article-title":"Carbon monoxide exposure improves immune function in lupus-prone mice","volume":"140","author":"Mackern-Oberti","year":"2013","journal-title":"Immunology"},{"key":"10.1016\/j.bcp.2022.115122_b0070","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.3389\/fphar.2020.01059","article-title":"Targeting the heme oxygenase 1\/carbon monoxide pathway to resolve lung hyper-inflammation and restore a regulated immune response in cystic fibrosis","volume":"11","author":"Di Pietro","year":"2020","journal-title":"Front. Pharmacol."},{"issue":"3","key":"10.1016\/j.bcp.2022.115122_b0075","doi-asserted-by":"crossref","first-page":"271","DOI":"10.4161\/viru.20328","article-title":"The potential of nitric oxide releasing therapies as antimicrobial agents","volume":"3","author":"Schairer","year":"2012","journal-title":"Virulence"},{"issue":"2","key":"10.1016\/j.bcp.2022.115122_b0080","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1089\/ars.2010.3678","article-title":"Mitochondria and sulfide: a very old story of poisoning, feeding, and signaling?","volume":"15","author":"Bouillaud","year":"2011","journal-title":"Antioxid. Redox Signal."},{"issue":"7","key":"10.1016\/j.bcp.2022.115122_b0085","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1007\/s00360-012-0654-y","article-title":"Mitochondrial adaptations to utilize hydrogen sulfide for energy and signaling","volume":"182","author":"Olson","year":"2012","journal-title":"J. Comp. Physiol. B."},{"issue":"2","key":"10.1016\/j.bcp.2022.115122_b0090","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.dld.2009.05.016","article-title":"Hydrogen sulphide synthesis in the rat and mouse gastrointestinal tract","volume":"42","author":"Martin","year":"2010","journal-title":"Dig. Liver Dis."},{"issue":"4","key":"10.1016\/j.bcp.2022.115122_b0095","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1097\/SHK.0b013e31802e27a0","article-title":"Suspended animation-like state protects mice from lethal hypoxia","volume":"27","author":"Blackstone","year":"2007","journal-title":"Shock"},{"issue":"1","key":"10.1016\/j.bcp.2022.115122_b0100","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.taap.2007.02.015","article-title":"Biological stress response terminology: Integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework","volume":"222","author":"Calabrese","year":"2007","journal-title":"Toxicol. Appl. Pharmacol."},{"issue":"3","key":"10.1016\/j.bcp.2022.115122_b0105","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.taap.2004.06.023","article-title":"The occurrence of hormetic dose responses in the toxicological literature, the hormesis database: an overview","volume":"202","author":"Calabrese","year":"2005","journal-title":"Toxicol. Appl. Pharmacol."},{"issue":"4","key":"10.1016\/j.bcp.2022.115122_b0110","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1590\/S1413-81232007000400017","article-title":"The importance of hormesis to public health","volume":"12","author":"Cook","year":"2007","journal-title":"Cien Saude Colet"},{"issue":"2","key":"10.1016\/j.bcp.2022.115122_b0115","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1177\/0960327107083417","article-title":"Hormesis and disease resistance: activation of cellular stress response pathways","volume":"27","author":"Mattson","year":"2008","journal-title":"Hum. Exp. Toxicol."},{"issue":"8","key":"10.1016\/j.bcp.2022.115122_b0120","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1016\/S0891-5849(02)01363-1","article-title":"Nitric oxide in cancer and chemoprevention","volume":"34","author":"Hofseth","year":"2003","journal-title":"Free Radic. Biol. Med."},{"issue":"1\u20132","key":"10.1016\/j.bcp.2022.115122_b0125","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.mam.2004.09.004","article-title":"Nitric oxide and neurological disorders","volume":"26","author":"Duncan","year":"2005","journal-title":"Mol. Aspects Med."},{"issue":"3","key":"10.1016\/j.bcp.2022.115122_b0130","doi-asserted-by":"crossref","first-page":"267","DOI":"10.2174\/0929867053363207","article-title":"Role of nitrosative stress and peroxynitrite in the pathogenesis of diabetic complications. Emerging new therapeutical strategies","volume":"12","author":"Pacher","year":"2005","journal-title":"Curr. Med. Chem."},{"issue":"6","key":"10.1016\/j.bcp.2022.115122_b0135","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1101\/lm.5.6.467","article-title":"On the respective roles of nitric oxide and carbon monoxide in long-term potentiation in the hippocampus","volume":"5","author":"Zhuo","year":"1998","journal-title":"Learn Mem."},{"issue":"12","key":"10.1016\/j.bcp.2022.115122_b0140","doi-asserted-by":"crossref","first-page":"1995","DOI":"10.1016\/j.freeradbiomed.2004.09.015","article-title":"Heme oxygenase expression in human central nervous system disorders","volume":"37","author":"Schipper","year":"2004","journal-title":"Free Radic. Biol. Med."},{"issue":"11","key":"10.1016\/j.bcp.2022.115122_b0145","doi-asserted-by":"crossref","first-page":"1763","DOI":"10.1089\/ars.2009.3074","article-title":"Cellular stress responses, the hormesis paradigm, and vitagenes: novel targets for therapeutic intervention in neurodegenerative disorders","volume":"13","author":"Calabrese","year":"2010","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.bcp.2022.115122_b0150","doi-asserted-by":"crossref","unstructured":"E. Dongo, L. Harasztos, G.L. Nadasy, L. Kiss, The effect of hydrogen sulfide on the contractility of cerebral arterioles. A pilot study, Physiol. Int. (2022).","DOI":"10.1556\/2060.2022.00190"},{"issue":"2","key":"10.1016\/j.bcp.2022.115122_b0155","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1124\/jpet.105.092023","article-title":"Role of hydrogen sulfide in the cardioprotection caused by ischemic preconditioning in the rat heart and cardiac myocytes","volume":"316","author":"Bian","year":"2006","journal-title":"J. Pharmacol. Exp. Ther."},{"issue":"2","key":"10.1016\/j.bcp.2022.115122_b0160","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1007\/s00380-003-0743-7","article-title":"The possible role of hydrogen sulfide as a smooth muscle cell proliferation inhibitor in rat cultured cells","volume":"19","author":"Du","year":"2004","journal-title":"Heart Vess."},{"issue":"2","key":"10.1016\/j.bcp.2022.115122_b0165","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1002\/jor.20060","article-title":"Nitric oxide enhances collagen synthesis in cultured human tendon cells","volume":"24","author":"Xia","year":"2006","journal-title":"J. Orthop. Res."},{"issue":"2","key":"10.1016\/j.bcp.2022.115122_b0170","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/j.apsb.2020.08.005","article-title":"Organic carbon monoxide prodrug, BW-CO-111, in protection against chemically-induced gastric mucosal damage","volume":"11","author":"Bakalarz","year":"2021","journal-title":"Acta Pharm. Sin. B"},{"issue":"6","key":"10.1016\/j.bcp.2022.115122_b0175","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1159\/000350097","article-title":"Hydrogen sulfide inhibits abnormal proliferation of lymphocytes via AKT\/GSK3beta signal pathway in systemic lupus erythematosus patients","volume":"31","author":"Han","year":"2013","journal-title":"Cell. Physiol. Biochem."},{"issue":"36","key":"10.1016\/j.bcp.2022.115122_b0180","doi-asserted-by":"crossref","first-page":"58089","DOI":"10.18632\/oncotarget.11166","article-title":"Preconditioning of bone marrow mesenchymal stem cells with hydrogen sulfide improves their therapeutic potential","volume":"7","author":"Zhang","year":"2016","journal-title":"Oncotarget"},{"issue":"3","key":"10.1016\/j.bcp.2022.115122_b0185","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1007\/s10974-010-9227-4","article-title":"Nitric oxide regulates stretch-induced proliferation in C2C12 myoblasts","volume":"31","author":"Soltow","year":"2010","journal-title":"J. Muscle Res. Cell. M."},{"key":"10.1016\/j.bcp.2022.115122_b0190","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.pbb.2013.11.009","article-title":"Hydrogen sulfide promotes proliferation and neuronal differentiation of neural stem cells and protects hypoxia-induced decrease in hippocampal neurogenesis","volume":"116","author":"Liu","year":"2014","journal-title":"Pharmacol. Biochem. Be."},{"issue":"10","key":"10.1016\/j.bcp.2022.115122_b0195","doi-asserted-by":"crossref","first-page":"7071","DOI":"10.1002\/jcp.26630","article-title":"Exogenous H2S exerts biphasic effects on porcine mammary epithelial cells proliferation through PI3K\/Akt-mTOR signaling pathway","volume":"233","author":"Zhang","year":"2018","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.bcp.2022.115122_b0200","doi-asserted-by":"crossref","first-page":"349","DOI":"10.2147\/DDDT.S343734","article-title":"Spray with nitric oxide donor accelerates wound healing: potential off-the-shelf solution for therapy?","volume":"16","author":"Igrunkova","year":"2022","journal-title":"Drug Des. Dev. Ther."},{"issue":"2","key":"10.1016\/j.bcp.2022.115122_b0205","doi-asserted-by":"crossref","first-page":"175","DOI":"10.4062\/biomolther.2018.009","article-title":"Carbon monoxide ameliorates 6-hydroxydopamine-induced cell death in c6 glioma cells","volume":"26","author":"Moon","year":"2018","journal-title":"Biomol. Ther."},{"issue":"1","key":"10.1016\/j.bcp.2022.115122_b0210","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.yrtph.2011.06.003","article-title":"The hormesis database: the occurrence of hormetic dose responses in the toxicological literature","volume":"61","author":"Calabrese","year":"2011","journal-title":"Regul. Toxicol. Pharm."},{"issue":"6","key":"10.1016\/j.bcp.2022.115122_b0215","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1165\/rcmb.2006-0329SM","article-title":"Oxidative-nitrosative stress and post-translational protein modifications: Implications to lung structure-function relations \u2013 arginase modulates NF-kappa B activity via a nitric oxide-dependent mechanism","volume":"36","author":"Ckless","year":"2007","journal-title":"Am. J. Res. Cell Mol."},{"key":"10.1016\/j.bcp.2022.115122_b0220","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2021.105526","article-title":"The hormetic dose-response mechanism: Nrf2 activation","volume":"167","author":"Calabrese","year":"2021","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.bcp.2022.115122_b0225","doi-asserted-by":"crossref","DOI":"10.1016\/j.arr.2021.101262","article-title":"Hydrogen sulfide in longevity and pathologies: inconsistency is malodorous","volume":"67","author":"Sokolov","year":"2021","journal-title":"Age. Res. Rev."},{"issue":"8","key":"10.1016\/j.bcp.2022.115122_b0230","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1007\/s12272-009-1807-8","article-title":"Role of Nrf2-mediated heme oxygenase-1 upregulation in adaptive survival response to nitrosative stress","volume":"32","author":"Surh","year":"2009","journal-title":"Arch. Pharm. Res."},{"key":"10.1016\/j.bcp.2022.115122_b0235","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.niox.2021.04.001","article-title":"A brief history of carbon monoxide and its therapeutic origins","volume":"111\u2013112","author":"Hopper","year":"2021","journal-title":"Nitric Oxide"},{"key":"10.1016\/j.bcp.2022.115122_b0240","series-title":"Carbon Monoxide Toxicity","author":"Hanley","year":"2020"},{"issue":"6","key":"10.1016\/j.bcp.2022.115122_b0245","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1113\/jphysiol.1896.sp000634","article-title":"The oxygen tension of arterial blood","volume":"20","author":"Haldane","year":"1896","journal-title":"J. Physiol."},{"key":"10.1016\/j.bcp.2022.115122_b0250","unstructured":"S. Wilbur, M. Williams, R. Williams, F. Scinicariello, J.M. Klotzbach, G.L. Diamond, M. Citra, Toxicological Profile for Carbon Monoxide, Atlanta (GA), 2012."},{"issue":"6","key":"10.1016\/j.bcp.2022.115122_b0255","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1111\/bph.12729","article-title":"Carbon monoxide and the CNS: challenges and achievements","volume":"172","author":"Queiroga","year":"2015","journal-title":"Br. J. Pharmacol."},{"issue":"8","key":"10.1016\/j.bcp.2022.115122_b0260","doi-asserted-by":"crossref","DOI":"10.3390\/ijms19082381","article-title":"Therapeutic aspects of carbon monoxide in cardiovascular disease","volume":"19","author":"Kim","year":"2018","journal-title":"Int. J. Mol. Sci."},{"issue":"5","key":"10.1016\/j.bcp.2022.115122_b0265","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.tips.2021.02.003","article-title":"Carbon monoxide: from poison to clinical trials","volume":"42","author":"Siracusa","year":"2021","journal-title":"Trends Pharmacol. Sci."},{"issue":"1","key":"10.1016\/j.bcp.2022.115122_b0270","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1081\/CLT-100102878","article-title":"Carbon monoxide cardiotoxicity","volume":"39","author":"Gandini","year":"2001","journal-title":"J. Toxicol. Clin. Toxicol."},{"issue":"7","key":"10.1016\/j.bcp.2022.115122_b0275","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1164\/rccm.201207-1341ED","article-title":"The paradox of carbon monoxide and the heart","volume":"186","author":"Schultz","year":"2012","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.bcp.2022.115122_b0280","doi-asserted-by":"crossref","first-page":"102183","DOI":"10.1016\/j.redox.2021.102183","article-title":"Carbon monoxide and a change of heart","volume":"48","author":"Chu","year":"2021","journal-title":"Redox. Biol."},{"issue":"15","key":"10.1016\/j.bcp.2022.115122_b0285","doi-asserted-by":"crossref","first-page":"2771","DOI":"10.2174\/1381612811319150013","article-title":"Carbon Monoxide and the brain: time to rethink the dogma","volume":"19","author":"Hanafy","year":"2013","journal-title":"Curr. Pharm. Des."},{"key":"10.1016\/j.bcp.2022.115122_b0290","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1172\/JCI104802","article-title":"Endogenous carbon monoxide production in man","volume":"42","author":"Coburn","year":"1963","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.bcp.2022.115122_b0295","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1146\/annurev.pharmtox.37.1.517","article-title":"The heme oxygenase system: a regulator of second messenger gases","volume":"37","author":"Maines","year":"1997","journal-title":"Annu. Rev. Pharmacol. Toxicol."},{"issue":"1","key":"10.1016\/j.bcp.2022.115122_b0300","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/S0021-9258(17)42488-4","article-title":"Characterization of two constitutive forms of rat liver microsomal heme oxygenase. Only one molecular species of the enzyme is inducible","volume":"261","author":"Maines","year":"1986","journal-title":"J. Biol. Chem."},{"issue":"2","key":"10.1016\/j.bcp.2022.115122_b0305","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1073\/pnas.61.2.748","article-title":"The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase","volume":"61","author":"Tenhunen","year":"1968","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"issue":"3","key":"10.1016\/j.bcp.2022.115122_b0310","first-page":"410","article-title":"The enzymatic catabolism of hemoglobin: stimulation of microsomal heme oxygenase by hemin","volume":"75","author":"Tenhunen","year":"1970","journal-title":"J. Lab. Clin. Med."},{"issue":"2","key":"10.1016\/j.bcp.2022.115122_b0315","first-page":"139","article-title":"Desensitization and deactivation of the secretory responsiveness of rabbit neutrophils induced by the chemotactic peptide, formyl-methionyl-leucyl-phenylalanine","volume":"25","author":"Showell","year":"1979","journal-title":"J. Reticuloendothel. Soc."},{"issue":"7","key":"10.1016\/j.bcp.2022.115122_b0320","doi-asserted-by":"crossref","first-page":"2568","DOI":"10.1073\/pnas.92.7.2568","article-title":"Basis of guanylate cyclase activation by carbon monoxide","volume":"92","author":"Kharitonov","year":"1995","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"issue":"30","key":"10.1016\/j.bcp.2022.115122_b0325","doi-asserted-by":"crossref","first-page":"20968","DOI":"10.1074\/jbc.M801501200","article-title":"Allostery in recombinant soluble guanylyl cyclase from Manduca sexta","volume":"283","author":"Hu","year":"2008","journal-title":"J. Biol. Chem."},{"issue":"4","key":"10.1016\/j.bcp.2022.115122_b0330","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1038\/74680","article-title":"Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway","volume":"6","author":"Otterbein","year":"2000","journal-title":"Nat. Med."},{"issue":"7","key":"10.1016\/j.bcp.2022.115122_b0335","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1084\/jem.192.7.1015","article-title":"Carbon monoxide generated by heme oxygenase 1 suppresses endothelial cell apoptosis","volume":"192","author":"Brouard","year":"2000","journal-title":"J. Exp. Med."},{"issue":"12","key":"10.1016\/j.bcp.2022.115122_b0340","doi-asserted-by":"crossref","first-page":"1520","DOI":"10.1016\/j.intimp.2010.08.026","article-title":"Carbon monoxide induces cyclooxygenase-2 expression through MAPKs and PKG in phagocytes","volume":"10","author":"Lin","year":"2010","journal-title":"Int. Immunopharmacol."},{"issue":"2","key":"10.1016\/j.bcp.2022.115122_b0345","doi-asserted-by":"crossref","DOI":"10.1152\/ajplung.2000.278.2.L312","article-title":"Heme oxygenase-1 inhibits TNF-alpha-induced apoptosis in cultured fibroblasts","volume":"278","author":"Petrache","year":"2000","journal-title":"Am. J. Physiol. Lung Cell. Mol. Physiol."},{"issue":"20","key":"10.1016\/j.bcp.2022.115122_b0350","doi-asserted-by":"crossref","first-page":"17950","DOI":"10.1074\/jbc.M108317200","article-title":"Heme oxygenase-1-derived carbon monoxide requires the activation of transcription factor NF-kappa B to protect endothelial cells from tumor necrosis factor-alpha-mediated apoptosis","volume":"277","author":"Brouard","year":"2002","journal-title":"J. Biol. Chem."},{"issue":"24","key":"10.1016\/j.bcp.2022.115122_b0355","doi-asserted-by":"crossref","first-page":"22061","DOI":"10.1074\/jbc.M301858200","article-title":"Carbon monoxide modulates Fas\/Fas ligand, caspases, and Bcl-2 family proteins via the p38alpha mitogen-activated protein kinase pathway during ischemia-reperfusion lung injury","volume":"278","author":"Zhang","year":"2003","journal-title":"J. Biol. Chem."},{"issue":"4","key":"10.1016\/j.bcp.2022.115122_b0360","doi-asserted-by":"crossref","first-page":"2622","DOI":"10.4049\/jimmunol.175.4.2622","article-title":"Heat shock protein-70 mediates the cytoprotective effect of carbon monoxide: involvement of p38 beta MAPK and heat shock factor-1","volume":"175","author":"Kim","year":"2005","journal-title":"J. Immunol."},{"key":"10.1016\/j.bcp.2022.115122_b0365","doi-asserted-by":"crossref","unstructured":"R.O. S, C.S. Queiroga, H.L. Vieira, Mitochondria and carbon monoxide: cytoprotection and control of cell metabolism - a role for Ca(2+)?, J. Physiol. 594(15) (2016) 4131\u20134138.","DOI":"10.1113\/JP270955"},{"issue":"12","key":"10.1016\/j.bcp.2022.115122_b0370","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1089\/ars.2014.6200","article-title":"Regulation of mitochondrial biogenesis and its intersection with inflammatory responses","volume":"22","author":"Cherry","year":"2015","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.bcp.2022.115122_b0375","doi-asserted-by":"crossref","first-page":"33","DOI":"10.3389\/fphys.2015.00033","article-title":"Carbon monoxide and mitochondria-modulation of cell metabolism, redox response and cell death","volume":"6","author":"Almeida","year":"2015","journal-title":"Front. Physiol."},{"key":"10.1016\/j.bcp.2022.115122_b0380","doi-asserted-by":"crossref","first-page":"794237","DOI":"10.1155\/2012\/794237","article-title":"Regulation of ROS production and vascular function by carbon monoxide","volume":"2012","author":"Choi","year":"2012","journal-title":"Oxid Med Cell Longev"},{"issue":"1","key":"10.1016\/j.bcp.2022.115122_b0385","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1007\/s11906-011-0238-3","article-title":"The Nox family of NADPH oxidases: friend or foe of the vascular system?","volume":"14","author":"Takac","year":"2012","journal-title":"Curr. Hypertens. Rep."},{"issue":"3","key":"10.1016\/j.bcp.2022.115122_b0390","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1007\/s00109-007-0276-0","article-title":"Heme oxygenase and carbon monoxide initiate homeostatic signaling","volume":"86","author":"Bilban","year":"2008","journal-title":"J Mol Med (Berl)"},{"issue":"2","key":"10.1016\/j.bcp.2022.115122_b0395","doi-asserted-by":"crossref","DOI":"10.1152\/ajpcell.00272.2010","article-title":"Nox4 NADPH oxidase-derived reactive oxygen species, via endogenous carbon monoxide, promote survival of brain endothelial cells during TNF-alpha-induced apoptosis","volume":"300","author":"Basuroy","year":"2011","journal-title":"Am. J. Physiol. Cell Physiol."},{"issue":"27","key":"10.1016\/j.bcp.2022.115122_b0400","doi-asserted-by":"crossref","first-page":"25350","DOI":"10.1074\/jbc.M503512200","article-title":"Mitochondrial respiratory chain and NAD(P)H oxidase are targets for the antiproliferative effect of carbon monoxide in human airway smooth muscle","volume":"280","author":"Taille","year":"2005","journal-title":"J. Biol. Chem."},{"issue":"1","key":"10.1016\/j.bcp.2022.115122_b0405","doi-asserted-by":"crossref","first-page":"77","DOI":"10.2217\/fnl.16.5","article-title":"Ischemic, traumatic and neurodegenerative brain inflammatory changes","volume":"11","author":"Dugue","year":"2016","journal-title":"Future Neurol."},{"issue":"2","key":"10.1016\/j.bcp.2022.115122_b0410","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1007\/s12640-009-9014-4","article-title":"Low doses of carbon monoxide protect against experimental focal brain ischemia","volume":"15","author":"Zeynalov","year":"2009","journal-title":"Neurotox. Res."},{"issue":"9","key":"10.1016\/j.bcp.2022.115122_b0415","doi-asserted-by":"crossref","first-page":"2605","DOI":"10.1161\/STROKEAHA.110.607101","article-title":"Carbon monoxide-activated Nrf2 pathway leads to protection against permanent focal cerebral ischemia","volume":"42","author":"Wang","year":"2011","journal-title":"Stroke"},{"issue":"14","key":"10.1016\/j.bcp.2022.115122_b0420","doi-asserted-by":"crossref","first-page":"10761","DOI":"10.1074\/jbc.M111.306738","article-title":"Carbon monoxide modulates apoptosis by reinforcing oxidative metabolism in astrocytes: role of Bcl-2","volume":"287","author":"Almeida","year":"2012","journal-title":"J. Biol. Chem."},{"issue":"8","key":"10.1016\/j.bcp.2022.115122_b0425","doi-asserted-by":"crossref","first-page":"e42632","DOI":"10.1371\/journal.pone.0042632","article-title":"Preconditioning triggered by carbon monoxide (CO) provides neuronal protection following perinatal hypoxia-ischemia","volume":"7","author":"Queiroga","year":"2012","journal-title":"PLoS ONE"},{"issue":"1","key":"10.1016\/j.bcp.2022.115122_b0430","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1186\/2045-9912-2-32","article-title":"Neuroprotective, neurotherapeutic, and neurometabolic effects of carbon monoxide","volume":"2","author":"Mahan","year":"2012","journal-title":"Med. Gas Res."},{"issue":"Suppl 1","key":"10.1016\/j.bcp.2022.115122_b0435","article-title":"Neuroprotective effert of carbon monoxide and Nrf2 in cerebral ischemia","volume":"4","author":"Dore","year":"2015","journal-title":"Springerplus"},{"issue":"1","key":"10.1016\/j.bcp.2022.115122_b0440","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1186\/s12974-018-1226-1","article-title":"Carbon monoxide-releasing molecule-3 protects against ischemic stroke by suppressing neuroinflammation and alleviating blood-brain barrier disruption","volume":"15","author":"Wang","year":"2018","journal-title":"J Neuroinflam."},{"issue":"11","key":"10.1016\/j.bcp.2022.115122_b0445","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1038\/nm.4188","article-title":"Dual effects of carbon monoxide on pericytes and neurogenesis in traumatic brain injury","volume":"22","author":"Choi","year":"2016","journal-title":"Nat. Med."},{"key":"10.1016\/j.bcp.2022.115122_b0450","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.pneurobio.2016.04.004","article-title":"Help-me signaling: Non-cell autonomous mechanisms of neuroprotection and neurorecovery","volume":"152","author":"Xing","year":"2017","journal-title":"Prog. Neurobiol."},{"issue":"5","key":"10.1016\/j.bcp.2022.115122_b0455","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1096\/fj.10-173450","article-title":"Carbon monoxide protects against oxidant-induced apoptosis via inhibition of Kv2.1","volume":"25","author":"Dallas","year":"2011","journal-title":"FASEB J."},{"issue":"2","key":"10.1016\/j.bcp.2022.115122_b0460","doi-asserted-by":"crossref","first-page":"93","DOI":"10.4062\/biomolther.2017.144","article-title":"Role of Carbon Monoxide in Neurovascular Repair Processing","volume":"26","author":"Choi","year":"2018","journal-title":"Biomol. Ther. (Seoul)"},{"issue":"2","key":"10.1016\/j.bcp.2022.115122_b0465","doi-asserted-by":"crossref","first-page":"81","DOI":"10.4103\/2045-9912.285561","article-title":"The role of carbon dioxide in acute brain injury","volume":"10","author":"Deng","year":"2020","journal-title":"Med. Gas Res."},{"issue":"1","key":"10.1016\/j.bcp.2022.115122_b0470","doi-asserted-by":"crossref","first-page":"45","DOI":"10.4103\/2045-9912.202909","article-title":"Carbon monoxide as a promising molecule to promote nerve regeneration after traumatic brain injury","volume":"7","author":"Qiao","year":"2017","journal-title":"Med. Gas Res."},{"key":"10.1016\/j.bcp.2022.115122_b0475","doi-asserted-by":"crossref","first-page":"e1569","DOI":"10.1038\/cddis.2014.529","article-title":"Heme oxygenase-1 protects against Alzheimer's amyloid-beta(1\u201342)-induced toxicity via carbon monoxide production","volume":"5","author":"Hettiarachchi","year":"2014","journal-title":"Cell Death Dis."},{"issue":"6","key":"10.1016\/j.bcp.2022.115122_b0480","doi-asserted-by":"crossref","first-page":"e2884","DOI":"10.1038\/cddis.2017.276","article-title":"Heme oxygenase-1 derived carbon monoxide suppresses Abeta1-42 toxicity in astrocytes","volume":"8","author":"Hettiarachchi","year":"2017","journal-title":"Cell Death Dis."},{"issue":"1","key":"10.1016\/j.bcp.2022.115122_b0485","doi-asserted-by":"crossref","first-page":"e0191207","DOI":"10.1371\/journal.pone.0191207","article-title":"Intermittent, low dose carbon monoxide exposure enhances survival and dopaminergic differentiation of human neural stem cells","volume":"13","author":"Dreyer-Andersen","year":"2018","journal-title":"PLoS ONE"},{"issue":"2","key":"10.1016\/j.bcp.2022.115122_b0490","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1172\/JCI28844","article-title":"Heme oxygenase-1 and carbon monoxide suppress autoimmune neuroinflammation","volume":"117","author":"Chora","year":"2007","journal-title":"J. Clin. Invest."},{"issue":"9","key":"10.1016\/j.bcp.2022.115122_b0495","doi-asserted-by":"crossref","first-page":"1841","DOI":"10.1097\/00001756-200107030-00016","article-title":"Heme oxygenase-1 plays an important protective role in experimental autoimmune encephalomyelitis","volume":"12","author":"Liu","year":"2001","journal-title":"NeuroReport"},{"issue":"5","key":"10.1016\/j.bcp.2022.115122_b0500","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1038\/sj.jcbfm.9600412","article-title":"Heme oxygenase-1 stabilizes the blood-spinal cord barrier and limits oxidative stress and white matter damage in the acutely injured murine spinal cord","volume":"27","author":"Lin","year":"2007","journal-title":"J. Cereb. Blood Flow Metab."},{"issue":"3","key":"10.1016\/j.bcp.2022.115122_b0505","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1111\/j.1365-2249.2010.04303.x","article-title":"Prevention of clinical and histological signs of proteolipid protein (PLP)-induced experimental allergic encephalomyelitis (EAE) in mice by the water-soluble carbon monoxide-releasing molecule (CORM)-A1","volume":"163","author":"Fagone","year":"2011","journal-title":"Clin. Exp. Immunol."},{"issue":"12","key":"10.1016\/j.bcp.2022.115122_b0510","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.2174\/1389450111009011517","article-title":"Targeting heme oxygenase-1 for neuroprotection and neuroinflammation in neurodegenerative diseases","volume":"11","author":"Jazwa","year":"2010","journal-title":"Curr. Drug Targets"},{"issue":"8","key":"10.1016\/j.bcp.2022.115122_b0515","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.1111\/j.1476-5381.1995.tb14948.x","article-title":"Conversion of inhaled nitric oxide to nitrate in man","volume":"114","author":"Westfelt","year":"1995","journal-title":"Br. J. Pharmacol."},{"issue":"1","key":"10.1016\/j.bcp.2022.115122_b0520","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1183\/09031936.93.02010056","article-title":"A simultaneous single breath measurement of pulmonary diffusing-capacity with nitric-oxide and carbon-monoxide","volume":"2","author":"Borland","year":"1989","journal-title":"Eur. Respir. J."},{"issue":"2","key":"10.1016\/j.bcp.2022.115122_b0525","doi-asserted-by":"crossref","DOI":"10.1136\/fn.72.2.F127","article-title":"The pharmacology of inhaled nitric-oxide","volume":"72","author":"Edwards","year":"1995","journal-title":"Arch. Disease Childhood-Fetal Neonatal Ed."},{"issue":"3","key":"10.1016\/j.bcp.2022.115122_b0530","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1113\/jphysiol.1957.sp005777","article-title":"The kinetics and equilibria of the reactions of nitric oxide with sheep haemoglobin","volume":"136","author":"Gibson","year":"1957","journal-title":"J. Physiol."},{"issue":"3","key":"10.1016\/j.bcp.2022.115122_b0535","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1001\/jama.1956.02970200001001","article-title":"Silo-filler's disease; a syndrome caused by nitrogen dioxide","volume":"162","author":"Lowry","year":"1956","journal-title":"J. Am. Med. Assoc."},{"issue":"1","key":"10.1016\/j.bcp.2022.115122_b0540","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1136\/thx.28.1.61","article-title":"Pulmonary effects of acute exposure to nitrous fumes","volume":"28","author":"Jones","year":"1973","journal-title":"Thorax"},{"issue":"2","key":"10.1016\/j.bcp.2022.115122_b0545","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1016\/0013-9351(83)90218-9","article-title":"Pulmonary NO2 toxicity in neonate and adult guinea pigs and rats","volume":"30","author":"Azoulay-Dupuis","year":"1983","journal-title":"Environ. Res."},{"issue":"1","key":"10.1016\/j.bcp.2022.115122_b0550","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1097\/00003246-199801000-00011","article-title":"Effects of inhaled nitric oxide in patients with acute respiratory distress syndrome: results of a randomized phase II trial. Inhaled nitric oxide in ARDS study group","volume":"26","author":"Dellinger","year":"1998","journal-title":"Crit. Care Med."},{"issue":"2","key":"10.1016\/j.bcp.2022.115122_b0555","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.cardiores.2006.02.025","article-title":"The role of oxidants and free radicals in reperfusion injury","volume":"70","author":"Zweier","year":"2006","journal-title":"Cardiovasc. Res."},{"issue":"7327","key":"10.1016\/j.bcp.2022.115122_b0560","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1038\/nature09599","article-title":"S-glutathionylation uncouples eNOS and regulates its cellular and vascular function","volume":"468","author":"Chen","year":"2010","journal-title":"Nature"},{"issue":"8","key":"10.1016\/j.bcp.2022.115122_b0565","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1038\/nm0895-804","article-title":"Enzyme-independent formation of nitric oxide in biological tissues","volume":"1","author":"Zweier","year":"1995","journal-title":"Nat. Med."},{"key":"10.1016\/j.bcp.2022.115122_b0570","doi-asserted-by":"crossref","unstructured":"U. Forstermann, W.C. Sessa, Nitric oxide synthases: regulation and function, Eur. Heart J. 33(7) (2012) 829\u2013837, 837a\u2013837d.","DOI":"10.1093\/eurheartj\/ehr304"},{"issue":"6122","key":"10.1016\/j.bcp.2022.115122_b0575","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1038\/327524a0","article-title":"Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor","volume":"327","author":"Palmer","year":"1987","journal-title":"Nature"},{"issue":"6","key":"10.1016\/j.bcp.2022.115122_b0580","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1161\/01.RES.61.6.866","article-title":"Endothelium-derived relaxing factor from pulmonary artery and vein possesses pharmacologic and chemical properties identical to those of nitric oxide radical","volume":"61","author":"Ignarro","year":"1987","journal-title":"Circ. Res."},{"issue":"4 Pt 1","key":"10.1016\/j.bcp.2022.115122_b0585","first-page":"503","article-title":"Nitric oxide as a unique signaling molecule in the vascular system: a historical overview","volume":"53","author":"Ignarro","year":"2002","journal-title":"J. Physiol. Pharmacol."},{"issue":"5","key":"10.1016\/j.bcp.2022.115122_b0590","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1182\/blood.V57.5.946.946","article-title":"Evidence for the inhibitory role of guanosine 3', 5'-monophosphate in ADP-induced human platelet aggregation in the presence of nitric oxide and related vasodilators","volume":"57","author":"Mellion","year":"1981","journal-title":"Blood"},{"issue":"1","key":"10.1016\/j.bcp.2022.115122_b0595","first-page":"147","article-title":"Vascular nitric oxide: formation and function","volume":"2010","author":"Jin","year":"2010","journal-title":"J. Blood Med."},{"issue":"2","key":"10.1016\/j.bcp.2022.115122_b0600","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1172\/JCI115877","article-title":"Bronchodilator action of inhaled nitric oxide in guinea pigs","volume":"90","author":"Dupuy","year":"1992","journal-title":"J. Clin. Invest."},{"issue":"2","key":"10.1016\/j.bcp.2022.115122_b0605","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/0014-2999(92)90676-U","article-title":"Nitric oxide is the endogenous neurotransmitter of bronchodilator nerves in humans","volume":"210","author":"Belvisi","year":"1992","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.bcp.2022.115122_b0610","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1146\/annurev.immunol.15.1.323","article-title":"Nitric oxide and macrophage function","volume":"15","author":"MacMicking","year":"1997","journal-title":"Annu. Rev. Immunol."},{"issue":"10","key":"10.1016\/j.bcp.2022.115122_b0615","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1038\/nrn2214","article-title":"Nitric oxide in the central nervous system: neuroprotection versus neurotoxicity","volume":"8","author":"Calabrese","year":"2007","journal-title":"Nat. Rev. Neurosci."},{"issue":"2","key":"10.1016\/j.bcp.2022.115122_b0620","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.pneurobio.2005.06.001","article-title":"The physiology and pathophysiology of nitric oxide in the brain","volume":"76","author":"Guix","year":"2005","journal-title":"Prog. Neurobiol."},{"issue":"9","key":"10.1016\/j.bcp.2022.115122_b0625","doi-asserted-by":"crossref","first-page":"5147","DOI":"10.1523\/JNEUROSCI.14-09-05147.1994","article-title":"Gases as biological messengers: nitric oxide and carbon monoxide in the brain","volume":"14","author":"Dawson","year":"1994","journal-title":"J. Neurosci."},{"issue":"2","key":"10.1016\/j.bcp.2022.115122_b0630","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1016\/0006-291X(89)91513-1","article-title":"Biosynthesis of endothelium-derived relaxing factor: a cytosolic enzyme in porcine aortic endothelial cells Ca2+-dependently converts L-arginine into an activator of soluble guanylyl cyclase","volume":"164","author":"Mayer","year":"1989","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bcp.2022.115122_b0635","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1146\/annurev.ph.57.030195.003423","article-title":"Nitric oxide synthases: properties and catalytic mechanism","volume":"57","author":"Griffith","year":"1995","journal-title":"Annu. Rev. Physiol."},{"issue":"8","key":"10.1016\/j.bcp.2022.115122_b0640","doi-asserted-by":"crossref","first-page":"1949","DOI":"10.1016\/j.bbadis.2018.11.007","article-title":"Functions and dysfunctions of nitric oxide in brain","volume":"1865","author":"Picon-Pages","year":"2019","journal-title":"Biochim. Biophys. Acta, Mol. Basis Dis."},{"issue":"5","key":"10.1016\/j.bcp.2022.115122_b0645","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1002\/path.1377","article-title":"Expression of nitric oxide synthase isoforms in human liver cirrhosis","volume":"200","author":"Mohammed","year":"2003","journal-title":"J. Pathol."},{"issue":"2","key":"10.1016\/j.bcp.2022.115122_b0650","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1124\/pr.57.2.1","article-title":"Modulation of prostaglandin biosynthesis by nitric oxide and nitric oxide donors","volume":"57","author":"Mollace","year":"2005","journal-title":"Pharmacol. Rev."},{"issue":"4","key":"10.1016\/j.bcp.2022.115122_b0655","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1089\/15230860260220111","article-title":"Regulation of heme oxygenase-1 by redox signals involving nitric oxide","volume":"4","author":"Motterlini","year":"2002","journal-title":"Antioxid. Redox Signal."},{"issue":"6","key":"10.1016\/j.bcp.2022.115122_b0660","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1016\/j.neuint.2004.03.021","article-title":"Role of nitric oxide in the regulation of neuronal proliferation, survival and differentiation","volume":"45","author":"Contestabile","year":"2004","journal-title":"Neurochem. Int."},{"issue":"2","key":"10.1016\/j.bcp.2022.115122_b0665","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/j.molcel.2005.12.006","article-title":"A nitric oxide signaling pathway controls CREB-mediated gene expression in neurons","volume":"21","author":"Riccio","year":"2006","journal-title":"Mol. Cell"},{"issue":"24","key":"10.1016\/j.bcp.2022.115122_b0670","doi-asserted-by":"crossref","first-page":"9265","DOI":"10.1073\/pnas.84.24.9265","article-title":"Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide","volume":"84","author":"Ignarro","year":"1987","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.bcp.2022.115122_b0675","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1146\/annurev.ph.57.030195.003343","article-title":"Nitric oxide signaling in the central nervous system","volume":"57","author":"Garthwaite","year":"1995","journal-title":"Annu. Rev. Physiol."},{"issue":"3 Pt 1","key":"10.1016\/j.bcp.2022.115122_b0680","article-title":"Nitric oxide as a mediator of nonadrenergic noncholinergic neurotransmission","volume":"262","author":"Sanders","year":"1992","journal-title":"Am. J. Physiol."},{"issue":"1","key":"10.1016\/j.bcp.2022.115122_b0685","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1046\/j.1471-4159.1998.71010266.x","article-title":"Nitric oxide-induced release of acetylcholine in the nucleus accumbens: role of cyclic GMP, glutamate, and GABA","volume":"71","author":"Prast","year":"1998","journal-title":"J. Neurochem."},{"issue":"1\u20132","key":"10.1016\/j.bcp.2022.115122_b0690","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/0006-8993(96)00127-8","article-title":"Biphasic modulation of GABA release by nitric oxide in the hippocampus of freely moving rats in vivo","volume":"717","author":"Getting","year":"1996","journal-title":"Brain Res."},{"issue":"2\u20133","key":"10.1016\/j.bcp.2022.115122_b0695","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/0014-2999(92)90759-W","article-title":"Nitric oxide induces neurotransmitter release from hippocampal slices","volume":"220","author":"Lonart","year":"1992","journal-title":"Eur. J. Pharmacol."},{"issue":"1","key":"10.1016\/j.bcp.2022.115122_b0700","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1097\/00001756-199310000-00024","article-title":"Nitric oxide increases dopamine and serotonin release in the medial preoptic area","volume":"5","author":"Lorrain","year":"1993","journal-title":"NeuroReport"},{"key":"10.1016\/j.bcp.2022.115122_b0705","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.expneurol.2014.10.017","article-title":"The role of the nitric oxide pathway in brain injury and its treatment\u2013from bench to bedside","volume":"263","author":"Garry","year":"2015","journal-title":"Exp. Neurol."},{"issue":"1","key":"10.1016\/j.bcp.2022.115122_b0710","doi-asserted-by":"crossref","first-page":"61","DOI":"10.2174\/092986710789957841","article-title":"Pharmacological modulation of nitric oxide release: new pharmacological perspectives, potential benefits and risks","volume":"17","author":"Scatena","year":"2010","journal-title":"Curr. Med. Chem."},{"issue":"2","key":"10.1016\/j.bcp.2022.115122_b0715","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/S0006-8993(00)02095-3","article-title":"Reduction of infarct size by the NO donors sodium nitroprusside and spermine\/NO after transient focal cerebral ischemia in rats","volume":"865","author":"Salom","year":"2000","journal-title":"Brain Res."},{"issue":"4","key":"10.1016\/j.bcp.2022.115122_b0720","doi-asserted-by":"crossref","first-page":"1952","DOI":"10.1111\/j.1471-4159.2008.05531.x","article-title":"Exogenous nitric oxide negatively regulates c-Jun N-terminal kinase activation via inhibiting endogenous NO-induced S-nitrosylation during cerebral ischemia and reperfusion in rat hippocampus","volume":"106","author":"Pei","year":"2008","journal-title":"J. Neurochem."},{"issue":"4","key":"10.1016\/j.bcp.2022.115122_b0725","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1016\/j.neuroscience.2008.03.061","article-title":"Coupling between neuronal nitric oxide synthase and glutamate receptor 6-mediated c-Jun N-terminal kinase signaling pathway via S-nitrosylation contributes to ischemia neuronal death","volume":"155","author":"Yu","year":"2008","journal-title":"Neuroscience"},{"issue":"1","key":"10.1016\/j.bcp.2022.115122_b0730","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/S0006-8993(02)03145-1","article-title":"Concurrent formation of peroxynitrite with the expression of inducible nitric oxide synthase in the brain during middle cerebral artery occlusion and reperfusion in rats","volume":"951","author":"Suzuki","year":"2002","journal-title":"Brain Res."},{"issue":"3","key":"10.1016\/j.bcp.2022.115122_b0735","doi-asserted-by":"crossref","first-page":"194","DOI":"10.4103\/2045-9912.215750","article-title":"The role of nitric oxide in stroke","volume":"7","author":"Chen","year":"2017","journal-title":"Med. Gas Res."},{"key":"10.1016\/j.bcp.2022.115122_b0740","doi-asserted-by":"crossref","first-page":"297357","DOI":"10.1155\/2013\/297357","article-title":"Nitric oxide donors as neuroprotective agents after an ischemic stroke-related inflammatory reaction","volume":"2013","author":"Godinez-Rubi","year":"2013","journal-title":"Oxid Med. Cell Longev."},{"key":"10.1016\/j.bcp.2022.115122_b0745","doi-asserted-by":"crossref","first-page":"154","DOI":"10.3389\/fncel.2017.00154","article-title":"NOSH-NBP, a novel nitric oxide and hydrogen sulfide- releasing hybrid. attenuates ischemic stroke-induced neuroinflammatory injury by modulating microglia polarization","volume":"11","author":"Ji","year":"2017","journal-title":"Front Cell Neurosci."},{"key":"10.1016\/j.bcp.2022.115122_b0750","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1186\/1742-2094-6-32","article-title":"Administration of S-nitrosoglutathione after traumatic brain injury protects the neurovascular unit and reduces secondary injury in a rat model of controlled cortical impact","volume":"6","author":"Khan","year":"2009","journal-title":"J. Neuroinflam."},{"issue":"4","key":"10.1016\/j.bcp.2022.115122_b0755","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1089\/neu.2018.5824","article-title":"Inhaled nitric oxide protects cerebral autoregulation and reduces hippocampal neuronal cell necrosis after traumatic brain injury in newborn and juvenile pigs","volume":"36","author":"Hekierski","year":"2019","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.bcp.2022.115122_b0760","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.brainres.2013.05.032","article-title":"Inhaled nitric oxide improves short term memory and reduces the inflammatory reaction in a mouse model of mild traumatic brain injury","volume":"1522","author":"Liu","year":"2013","journal-title":"Brain Res."},{"issue":"2","key":"10.1016\/j.bcp.2022.115122_b0765","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1038\/jcbfm.2012.176","article-title":"Inhaled nitric oxide reduces secondary brain damage after traumatic brain injury in mice","volume":"33","author":"Terpolilli","year":"2013","journal-title":"J. Cereb. Blood Flow Metab."},{"issue":"25","key":"10.1016\/j.bcp.2022.115122_b0770","doi-asserted-by":"crossref","first-page":"2837","DOI":"10.2174\/138161210793176590","article-title":"Nitric oxide: target for therapeutic strategies in Alzheimer's disease","volume":"16","author":"Fernandez","year":"2010","journal-title":"Curr. Pharm. Des."},{"issue":"2","key":"10.1016\/j.bcp.2022.115122_b0775","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1590\/S0100-879X2009000200001","article-title":"Pharmacological effects and behavioral interventions on memory consolidation and reconsolidation","volume":"42","author":"Baratti","year":"2009","journal-title":"Braz. J. Med. Biol. Res."},{"issue":"17","key":"10.1016\/j.bcp.2022.115122_b0780","doi-asserted-by":"crossref","first-page":"6893","DOI":"10.1523\/JNEUROSCI.4002-14.2015","article-title":"Nitric oxide signaling is recruited as a compensatory mechanism for sustaining synaptic plasticity in Alzheimer's disease mice","volume":"35","author":"Chakroborty","year":"2015","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bcp.2022.115122_b0785","doi-asserted-by":"crossref","first-page":"3806157","DOI":"10.1155\/2016\/3806157","article-title":"Getting to NO Alzheimer's disease: neuroprotection versus neurotoxicity mediated by nitric oxide","volume":"2016","author":"Balez","year":"2016","journal-title":"Oxid Med. Cell Longev."},{"issue":"24","key":"10.1016\/j.bcp.2022.115122_b0790","doi-asserted-by":"crossref","first-page":"2666","DOI":"10.2174\/0929867323666160812151356","article-title":"An update on the role of nitric oxide in the neurodegenerative processes of Parkinson's disease","volume":"23","author":"Jimenez-Jimenez","year":"2016","journal-title":"Curr. Med. Chem."},{"issue":"12","key":"10.1016\/j.bcp.2022.115122_b0795","doi-asserted-by":"crossref","first-page":"1975","DOI":"10.1001\/archneur.58.12.1975","article-title":"Investigating chemokines and chemokine receptors in patients with multiple sclerosis: opportunities and challenges","volume":"58","author":"Trebst","year":"2001","journal-title":"Arch. Neurol."},{"issue":"1\u20132","key":"10.1016\/j.bcp.2022.115122_b0800","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/S0165-5728(97)00180-X","article-title":"Aminoguanidine, a selective inhibitor of the inducible nitric oxide synthase, has different effects on experimental allergic encephalomyelitis in the induction and progression phase","volume":"81","author":"Okuda","year":"1998","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.bcp.2022.115122_b0805","doi-asserted-by":"crossref","first-page":"322","DOI":"10.3389\/fncel.2015.00322","article-title":"Implications of glial nitric oxide in neurodegenerative diseases","volume":"9","author":"Yuste","year":"2015","journal-title":"Front. Cell. Neurosci."},{"issue":"5","key":"10.1016\/j.bcp.2022.115122_b0810","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1016\/j.bcp.2012.10.019","article-title":"Biology and therapeutic potential of hydrogen sulfide and hydrogen sulfide-releasing chimeras","volume":"85","author":"Kashfi","year":"2013","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.bcp.2022.115122_b0815","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1146\/annurev.pa.32.040192.000545","article-title":"Toxicology of hydrogen sulfide","volume":"32","author":"Reiffenstein","year":"1992","journal-title":"Annu. Rev. Pharmacol. Toxicol."},{"issue":"9","key":"10.1016\/j.bcp.2022.115122_b0820","doi-asserted-by":"crossref","first-page":"1380","DOI":"10.2105\/AJPH.91.9.1380","article-title":"De morbis artificum diatriba [diseases of workers]. 1713","volume":"91","author":"Ramazzini","year":"2001","journal-title":"Am. J. Public Health"},{"issue":"12","key":"10.1016\/j.bcp.2022.115122_b0825","article-title":"Hydrogen sulfide and carnosine: modulation of oxidative stress and inflammation in kidney and brain axis","volume":"9","author":"Calabrese","year":"2020","journal-title":"Antioxidants (Basel)"},{"issue":"8","key":"10.1016\/j.bcp.2022.115122_b0830","doi-asserted-by":"crossref","first-page":"2099","DOI":"10.1111\/bph.12369","article-title":"Regulation of mitochondrial bioenergetic function by hydrogen sulfide. Part I. Biochemical and physiological mechanisms","volume":"171","author":"Szabo","year":"2014","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.bcp.2022.115122_b0835","doi-asserted-by":"crossref","first-page":"101772","DOI":"10.1016\/j.redox.2020.101772","article-title":"Effects of hydrogen sulfide on mitochondrial function and cellular bioenergetics","volume":"38","author":"Paul","year":"2021","journal-title":"Redox Biol."},{"issue":"5","key":"10.1016\/j.bcp.2022.115122_b0840","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1093\/occmed\/46.5.367","article-title":"Hydrogen sulphide","volume":"46","author":"Guidotti","year":"1996","journal-title":"Occup Med (Lond)"},{"issue":"6","key":"10.1016\/j.bcp.2022.115122_b0845","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1177\/1091581810384882","article-title":"Hydrogen sulfide: advances in understanding human toxicity","volume":"29","author":"Guidotti","year":"2010","journal-title":"Int J Toxicol"},{"issue":"Suppl 1","key":"10.1016\/j.bcp.2022.115122_b0850","article-title":"Fatal accidental hydrogen sulfide poisoning: a domestic case","volume":"58","author":"Sastre","year":"2013","journal-title":"J. Forensic Sci."},{"issue":"1","key":"10.1016\/j.bcp.2022.115122_b0855","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1093\/toxsci\/65.1.18","article-title":"Cytochrome oxidase inhibition induced by acute hydrogen sulfide inhalation: correlation with tissue sulfide concentrations in the rat brain, liver, lung, and nasal epithelium","volume":"65","author":"Dorman","year":"2002","journal-title":"Toxicol. Sci."},{"issue":"6","key":"10.1016\/j.bcp.2022.115122_b0860","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1016\/0006-2952(89)90288-8","article-title":"Acute hydrogen sulfide poisoning. Demonstration of selective uptake of sulfide by the brainstem by measurement of brain sulfide levels","volume":"38","author":"Warenycia","year":"1989","journal-title":"Biochem. Pharmacol."},{"issue":"4","key":"10.1016\/j.bcp.2022.115122_b0865","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1080\/03602530600959607","article-title":"Molecular mechanisms of hydrogen sulfide toxicity","volume":"38","author":"Truong","year":"2006","journal-title":"Drug Metab. Rev."},{"issue":"5","key":"10.1016\/j.bcp.2022.115122_b0870","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1007\/s12012-018-9451-5","article-title":"Methylene blue counteracts H2S-induced cardiac ion channel dysfunction and ATP reduction","volume":"18","author":"Cheung","year":"2018","journal-title":"Cardiovasc. Toxicol."},{"issue":"11","key":"10.1016\/j.bcp.2022.115122_b0875","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1093\/abbs\/gmv098","article-title":"H2S protects PC12 cells against toxicity of corticosterone by modulation of BDNF-TrkB pathway","volume":"47","author":"Gao","year":"2015","journal-title":"Acta Biochim. Biophys. Sin. (Shanghai)"},{"issue":"2","key":"10.1016\/j.bcp.2022.115122_b0880","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/S0021-9258(19)50824-9","article-title":"Enzymatic desulfuration of beta-mercaptopyruvate to pyruvate","volume":"206","author":"Meister","year":"1954","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bcp.2022.115122_b0885","first-page":"253","article-title":"The mechanism of desulphhydration of cysteine","volume":"24","author":"Cavallini","year":"1962","journal-title":"Enzymologia"},{"issue":"1","key":"10.1016\/j.bcp.2022.115122_b0890","first-page":"247","article-title":"Specificity and some other properties of liver serine sulphhydrase: evidence for its identity with cystathionine -synthase","volume":"242","author":"Braunstein","year":"1971","journal-title":"BBA"},{"issue":"2","key":"10.1016\/j.bcp.2022.115122_b0895","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1093\/jat\/13.2.105","article-title":"Determination of sulfide in brain tissue by gas dialysis\/ion chromatography: postmortem studies and two case reports","volume":"13","author":"Goodwin","year":"1989","journal-title":"J. Anal. Toxicol."},{"issue":"2","key":"10.1016\/j.bcp.2022.115122_b0900","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1089\/ars.2008.2132","article-title":"A source of hydrogen sulfide and a mechanism of its release in the brain","volume":"11","author":"Ishigami","year":"2009","journal-title":"Antioxid. Redox Signal."},{"issue":"4","key":"10.1016\/j.bcp.2022.115122_b0905","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1111\/j.1476-5381.2010.00704.x","article-title":"A monobromobimane-based assay to measure the pharmacokinetic profile of reactive sulphide species in blood","volume":"160","author":"Wintner","year":"2010","journal-title":"Br. J. Pharmacol."},{"issue":"11","key":"10.1016\/j.bcp.2022.115122_b0910","first-page":"1518","article-title":"PLP-dependent H(2)S biogenesis","volume":"1814","author":"Singh","year":"2011","journal-title":"BBA"},{"issue":"4","key":"10.1016\/j.bcp.2022.115122_b0915","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1089\/ars.2008.2253","article-title":"3-Mercaptopyruvate sulfurtransferase produces hydrogen sulfide and bound sulfane sulfur in the brain","volume":"11","author":"Shibuya","year":"2009","journal-title":"Antioxid. Redox Signal."},{"issue":"3","key":"10.1016\/j.bcp.2022.115122_b0920","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1523\/JNEUROSCI.16-03-01066.1996","article-title":"The possible role of hydrogen sulfide as an endogenous neuromodulator","volume":"16","author":"Abe","year":"1996","journal-title":"J. Neurosci."},{"issue":"13","key":"10.1016\/j.bcp.2022.115122_b0925","doi-asserted-by":"crossref","first-page":"1854","DOI":"10.1096\/fj.05-3724fje","article-title":"Cystathionine beta-synthase, a key enzyme for homocysteine metabolism, is preferentially expressed in the radial glia\/astrocyte lineage of developing mouse CNS","volume":"19","author":"Enokido","year":"2005","journal-title":"FASEB J."},{"issue":"10","key":"10.1016\/j.bcp.2022.115122_b0930","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1096\/fj.04-1815fje","article-title":"Hydrogen sulfide protects neurons from oxidative stress","volume":"18","author":"Kimura","year":"2004","journal-title":"FASEB J."},{"issue":"2","key":"10.1016\/j.bcp.2022.115122_b0935","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1002\/glia.20362","article-title":"Hydrogen sulphide regulates calcium homeostasis in microglial cells","volume":"54","author":"Lee","year":"2006","journal-title":"Glia"},{"issue":"5","key":"10.1016\/j.bcp.2022.115122_b0940","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1089\/ars.2013.5339","article-title":"Enzymology of H2S biogenesis, decay and signaling","volume":"20","author":"Kabil","year":"2014","journal-title":"Antioxid. Redox Signal."},{"issue":"5","key":"10.1016\/j.bcp.2022.115122_b0945","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1093\/jb\/mvp111","article-title":"Vascular endothelium expresses 3-mercaptopyruvate sulfurtransferase and produces hydrogen sulfide","volume":"146","author":"Shibuya","year":"2009","journal-title":"J. Biochem."},{"issue":"17","key":"10.1016\/j.bcp.2022.115122_b0950","doi-asserted-by":"crossref","first-page":"11601","DOI":"10.1074\/jbc.M808026200","article-title":"H2S biogenesis by human cystathionine gamma-lyase leads to the novel sulfur metabolites lanthionine and homolanthionine and is responsive to the grade of hyperhomocysteinemia","volume":"284","author":"Chiku","year":"2009","journal-title":"J. Biol. Chem."},{"issue":"5901","key":"10.1016\/j.bcp.2022.115122_b0955","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1126\/science.1162667","article-title":"H2S as a physiologic vasorelaxant: hypertension in mice with deletion of cystathionine gamma-lyase","volume":"322","author":"Yang","year":"2008","journal-title":"Science"},{"key":"10.1016\/j.bcp.2022.115122_b0960","doi-asserted-by":"crossref","first-page":"14774","DOI":"10.1038\/srep14774","article-title":"Identification of H2S3 and H2S produced by 3-mercaptopyruvate sulfurtransferase in the brain","volume":"5","author":"Kimura","year":"2015","journal-title":"Sci. Rep."},{"issue":"1","key":"10.1016\/j.bcp.2022.115122_b0965","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1089\/ars.2011.4345","article-title":"Hydrogen sulfide is a signaling molecule and a cytoprotectant","volume":"17","author":"Kimura","year":"2012","journal-title":"Antioxid. Redox Signal."},{"issue":"10","key":"10.1016\/j.bcp.2022.115122_b0970","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1021\/cn500185g","article-title":"Hydrogen sulfide: a neuromodulator and neuroprotectant in the central nervous system","volume":"5","author":"Zhang","year":"2014","journal-title":"ACS Chem. Neurosci."},{"key":"10.1016\/j.bcp.2022.115122_b0975","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/s40035-018-0108-x","article-title":"Hydrogen sulfide, nitric oxide, and neurodegenerative disorders","volume":"7","author":"Panthi","year":"2018","journal-title":"Transl Neurodegener"},{"issue":"1","key":"10.1016\/j.bcp.2022.115122_b0980","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1089\/ars.2008.2282","article-title":"Hydrogen sulfide increases glutathione production and suppresses oxidative stress in mitochondria","volume":"12","author":"Kimura","year":"2010","journal-title":"Antioxid. Redox Signal."},{"issue":"1","key":"10.1016\/j.bcp.2022.115122_b0985","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1006\/bbrc.1999.1915","article-title":"Hydrogen sulfide induces cyclic AMP and modulates the NMDA receptor","volume":"267","author":"Kimura","year":"2000","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"4","key":"10.1016\/j.bcp.2022.115122_b0990","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1111\/j.1471-4159.2006.04283.x","article-title":"Hydrogen sulfide attenuates lipopolysaccharide-induced inflammation by inhibition of p38 mitogen-activated protein kinase in microglia","volume":"100","author":"Hu","year":"2007","journal-title":"J. Neurochem."},{"key":"10.1016\/j.bcp.2022.115122_b0995","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.niox.2019.05.008","article-title":"Hydrogen sulfide suppresses homocysteine-induced glial activation and inflammatory response","volume":"90","author":"Kumar","year":"2019","journal-title":"Nitric Oxide"},{"key":"10.1016\/j.bcp.2022.115122_b1000","doi-asserted-by":"crossref","first-page":"17","DOI":"10.3389\/fncel.2020.00017","article-title":"Early neurotoxic effects of inorganic arsenic modulate cortical GSH levels associated with the activation of the Nrf2 and NFkappaB pathways. Expression of amino acid transporters and NMDA receptors and the production of hydrogen sulfide","volume":"14","author":"Silva-Adaya","year":"2020","journal-title":"Front Cell Neurosci."},{"issue":"1","key":"10.1016\/j.bcp.2022.115122_b1005","doi-asserted-by":"crossref","DOI":"10.3390\/ijms19010099","article-title":"Cellular and molecular mechanisms underlying non-pharmaceutical ischemic stroke therapy in aged subjects","volume":"19","author":"Sandu","year":"2017","journal-title":"Int. J. Mol. Sci."},{"issue":"18","key":"10.1016\/j.bcp.2022.115122_b1010","doi-asserted-by":"crossref","first-page":"2351","DOI":"10.1161\/CIRCULATIONAHA.107.753467","article-title":"Characterization of a novel, water-soluble hydrogen sulfide-releasing molecule (GYY4137): new insights into the biology of hydrogen sulfide","volume":"117","author":"Li","year":"2008","journal-title":"Circulation"},{"issue":"2","key":"10.1016\/j.bcp.2022.115122_b1015","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1136\/svn-2018-000194","article-title":"H2S-based therapies for ischaemic stroke: opportunities and challenges","volume":"4","author":"Jia","year":"2019","journal-title":"Stroke Vasc. Neurol."},{"issue":"11","key":"10.1016\/j.bcp.2022.115122_b1020","doi-asserted-by":"crossref","DOI":"10.3390\/molecules23112828","article-title":"8e protects against acute cerebral ischemia by inhibition of PI3Kgamma-mediated superoxide generation in microglia","volume":"23","author":"Wang","year":"2018","journal-title":"Molecules"},{"key":"10.1016\/j.bcp.2022.115122_b1025","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.brainres.2010.05.017","article-title":"Dynamic change of hydrogen sulfide during global cerebral ischemia-reperfusion and its effect in rats","volume":"1345","author":"Ren","year":"2010","journal-title":"Brain Res."},{"issue":"6","key":"10.1016\/j.bcp.2022.115122_b1030","doi-asserted-by":"crossref","first-page":"932","DOI":"10.4103\/1673-5374.158353","article-title":"Hydrogen sulfide intervention in focal cerebral ischemia\/reperfusion injury in rats","volume":"10","author":"Li","year":"2015","journal-title":"Neural Regen. Res."},{"issue":"5","key":"10.1016\/j.bcp.2022.115122_b1035","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1111\/jnc.12695","article-title":"Hydrogen sulfide protects blood-brain barrier integrity following cerebral ischemia","volume":"129","author":"Wang","year":"2014","journal-title":"J. Neurochem."},{"issue":"3","key":"10.1016\/j.bcp.2022.115122_b1040","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1007\/s12975-016-0459-5","article-title":"Hydrogen sulfide attenuates tissue plasminogen activator-induced cerebral hemorrhage following experimental stroke","volume":"7","author":"Liu","year":"2016","journal-title":"Transl. Stroke Res."},{"issue":"9","key":"10.1016\/j.bcp.2022.115122_b1045","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1111\/j.1440-1681.2012.05731.x","article-title":"Dual effects of hydrogen sulphide on focal cerebral ischaemic injury via modulation of oxidative stress-induced apoptosis","volume":"39","author":"Li","year":"2012","journal-title":"Clin. Exp. Pharmacol. Physiol."},{"issue":"3","key":"10.1016\/j.bcp.2022.115122_b1050","first-page":"335","article-title":"Hydrogen sulfide plays an important protective role by influencing autophagy in diseases","volume":"68","author":"Wang","year":"2019","journal-title":"Physiol. Res."},{"issue":"12","key":"10.1016\/j.bcp.2022.115122_b1055","doi-asserted-by":"crossref","first-page":"1741","DOI":"10.1089\/ars.2013.5587","article-title":"CaMKKbeta-dependent activation of AMP-activated protein kinase is critical to suppressive effects of hydrogen sulfide on neuroinflammation","volume":"21","author":"Zhou","year":"2014","journal-title":"Antioxid. Redox Signal."},{"issue":"4","key":"10.1016\/j.bcp.2022.115122_b1060","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1159\/000430317","article-title":"ROS-dependent neuroprotective effects of nahs in ischemia brain injury involves the PARP\/AIF pathway","volume":"36","author":"Yu","year":"2015","journal-title":"Cell. Physiol. Biochem."},{"key":"10.1016\/j.bcp.2022.115122_b1065","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.brainresbull.2015.12.007","article-title":"Preconditioning of H2S inhalation protects against cerebral ischemia\/reperfusion injury by induction of HSP70 through PI3K\/Akt\/Nrf2 pathway","volume":"121","author":"Ji","year":"2016","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.bcp.2022.115122_b1070","doi-asserted-by":"crossref","first-page":"349","DOI":"10.3389\/fncel.2019.00349","article-title":"Exogenous hydrogen sulfide offers neuroprotection on intracerebral hemorrhage injury through modulating endogenous H2S metabolism in mice","volume":"13","author":"Shan","year":"2019","journal-title":"Front. Cell. Neurosci."},{"issue":"18","key":"10.1016\/j.bcp.2022.115122_b1075","doi-asserted-by":"crossref","DOI":"10.3390\/ijms221810099","article-title":"Hydrogen sulfide reduces ischemia and reperfusion injury in neuronal cells in a dose- and time-dependent manner","volume":"22","author":"Scheid","year":"2021","journal-title":"Int. J. Mol. Sci."},{"issue":"11","key":"10.1016\/j.bcp.2022.115122_b1080","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1139\/cjpp-2016-0100","article-title":"Exogenous hydrogen sulfide attenuates cerebral ischemia-reperfusion injury by inhibiting autophagy in mice","volume":"94","author":"Shui","year":"2016","journal-title":"Can. J. Physiol. Pharmacol."},{"issue":"2","key":"10.1016\/j.bcp.2022.115122_b1085","doi-asserted-by":"crossref","DOI":"10.1016\/j.jss.2013.03.067","article-title":"Protective effects of hydrogen sulfide in a rat model of traumatic brain injury via activation of mitochondrial adenosine triphosphate-sensitive potassium channels and reduction of oxidative stress","volume":"184","author":"Jiang","year":"2013","journal-title":"J. Surg. Res."},{"key":"10.1016\/j.bcp.2022.115122_b1090","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.neuint.2013.11.002","article-title":"Role of hydrogen sulfide in secondary neuronal injury","volume":"64","author":"Wang","year":"2014","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.bcp.2022.115122_b1095","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.cbi.2018.02.028","article-title":"NaHS restores mitochondrial function and inhibits autophagy by activating the PI3K\/Akt\/mTOR signalling pathway to improve functional recovery after traumatic brain injury","volume":"286","author":"Xu","year":"2018","journal-title":"Chem. Biol. Interact."},{"issue":"5","key":"10.1016\/j.bcp.2022.115122_b1100","doi-asserted-by":"crossref","first-page":"7180","DOI":"10.18632\/aging.202575","article-title":"Neuroprotective effect of hydrogen sulfide against glutamate-induced oxidative stress is mediated via the p53\/glutaminase 2 pathway after traumatic brain injury","volume":"13","author":"Sun","year":"2021","journal-title":"Aging (Albany NY)"},{"key":"10.1016\/j.bcp.2022.115122_b1105","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1186\/s12974-014-0196-1","article-title":"Hydrogen sulfide-releasing cyclooxygenase inhibitor ATB-346 enhances motor function and reduces cortical lesion volume following traumatic brain injury in mice","volume":"11","author":"Campolo","year":"2014","journal-title":"J. Neuroinflam."},{"key":"10.1016\/j.bcp.2022.115122_b1110","doi-asserted-by":"crossref","first-page":"105636","DOI":"10.1016\/j.biocel.2019.105636","article-title":"Hydrogen sulfide protects against cell damage through modulation of PI3K\/Akt\/Nrf2 signaling","volume":"117","author":"Zhang","year":"2019","journal-title":"Int. J. Biochem. Cell Biol."},{"issue":"1","key":"10.1016\/j.bcp.2022.115122_b1115","doi-asserted-by":"crossref","first-page":"e87241","DOI":"10.1371\/journal.pone.0087241","article-title":"Hydrogen sulfide offers neuroprotection on traumatic brain injury in parallel with reduced apoptosis and autophagy in mice","volume":"9","author":"Zhang","year":"2014","journal-title":"PLoS ONE"},{"key":"10.1016\/j.bcp.2022.115122_b1120","doi-asserted-by":"crossref","first-page":"7301615","DOI":"10.1155\/2020\/7301615","article-title":"Biologic effect of hydrogen sulfide and its role in traumatic brain injury","volume":"2020","author":"Zhang","year":"2020","journal-title":"Oxid. Med. Cell Longev."},{"issue":"19","key":"10.1016\/j.bcp.2022.115122_b1125","doi-asserted-by":"crossref","first-page":"2634","DOI":"10.1089\/neu.2021.0053","article-title":"Inhalational gases for neuroprotection in traumatic brain injury","volume":"38","author":"Shin","year":"2021","journal-title":"J. Neurotrauma"},{"issue":"5","key":"10.1016\/j.bcp.2022.115122_b1130","first-page":"3789","article-title":"A new hope for a devastating disease: hydrogen sulfide in Parkinson's disease","volume":"55","author":"Cao","year":"2018","journal-title":"Mol. Neurobiol."},{"issue":"1","key":"10.1016\/j.bcp.2022.115122_b1135","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.yexcr.2016.09.006","article-title":"Hydrogen sulfide inhibits MPP(+)-induced aldehyde stress and endoplasmic reticulum stress in PC12 cells: involving upregulation of BDNF","volume":"348","author":"Xiao","year":"2016","journal-title":"Exp. Cell Res."},{"issue":"1\u20132","key":"10.1016\/j.bcp.2022.115122_b1140","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1007\/s11010-020-03801-y","article-title":"Hydrogen sulfide alleviates oxidative stress injury and reduces apoptosis induced by MPP(+) in Parkinson's disease cell model","volume":"472","author":"Liu","year":"2020","journal-title":"Mol. Cell. Biochem."},{"issue":"4","key":"10.1016\/j.bcp.2022.115122_b1145","doi-asserted-by":"crossref","first-page":"e60200","DOI":"10.1371\/journal.pone.0060200","article-title":"Therapeutic effect of hydrogen sulfide-releasing L-Dopa derivative ACS84 on 6-OHDA-induced Parkinson's disease rat model","volume":"8","author":"Xie","year":"2013","journal-title":"PLoS ONE"},{"issue":"2","key":"10.1016\/j.bcp.2022.115122_b1150","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1089\/ars.2010.3671","article-title":"Inhaled hydrogen sulfide prevents neurodegeneration and movement disorder in a mouse model of Parkinson's disease","volume":"15","author":"Kida","year":"2011","journal-title":"Antioxid. Redox Signal."},{"issue":"6","key":"10.1016\/j.bcp.2022.115122_b1155","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1089\/ars.2011.4507","article-title":"The neuroprotection of hydrogen sulfide against MPTP-induced dopaminergic neuron degeneration involves uncoupling protein 2 rather than ATP-sensitive potassium channels","volume":"17","author":"Lu","year":"2012","journal-title":"Antioxid. Redox Signal."},{"issue":"8","key":"10.1016\/j.bcp.2022.115122_b1160","doi-asserted-by":"crossref","first-page":"3500","DOI":"10.1021\/acschemneuro.9b00120","article-title":"Tacrine-hydrogen sulfide donor hybrid ameliorates cognitive impairment in the aluminum chloride mouse model of Alzheimer's disease","volume":"10","author":"Cheng","year":"2019","journal-title":"ACS Chem. Neurosci."},{"issue":"1\u20132","key":"10.1016\/j.bcp.2022.115122_b1165","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1159\/000494113","article-title":"Mechanisms of hydrogen sulfide against the progression of severe Alzheimer's disease in transgenic mice at different ages","volume":"103","author":"Vandini","year":"2019","journal-title":"Pharmacology"},{"issue":"4","key":"10.1016\/j.bcp.2022.115122_b1170","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1007\/s12640-019-00152-5","article-title":"Hydrogen sulfide attenuates the neurotoxicity in the animal model of fetal alcohol spectrum disorders","volume":"37","author":"Mohseni","year":"2020","journal-title":"Neurotox. Res."},{"key":"10.1016\/j.bcp.2022.115122_b1175","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.neuint.2018.07.010","article-title":"Hydrogen sulfide attenuates homocysteine-induced neurotoxicity by preventing mitochondrial dysfunctions and oxidative damage: In vitro and in vivo studies","volume":"120","author":"Kumar","year":"2018","journal-title":"Neurochem. Int."},{"issue":"1","key":"10.1016\/j.bcp.2022.115122_b1180","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1007\/s12031-018-1218-8","article-title":"Hydrogen sulfide protects hippocampal neurons against methamphetamine neurotoxicity via inhibition of apoptosis and neuroinflammation","volume":"67","author":"Ghanbari","year":"2019","journal-title":"J. Mol. Neurosci."},{"issue":"4","key":"10.1016\/j.bcp.2022.115122_b1185","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2017225118","article-title":"Hydrogen sulfide is neuroprotective in Alzheimer's disease by sulfhydrating GSK3beta and inhibiting Tau hyperphosphorylation","volume":"118","author":"Giovinazzo","year":"2021","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"issue":"4","key":"10.1016\/j.bcp.2022.115122_b1190","doi-asserted-by":"crossref","first-page":"653","DOI":"10.4103\/1673-5374.266911","article-title":"Therapeutic importance of hydrogen sulfide in age-associated neurodegenerative diseases","volume":"15","author":"Tabassum","year":"2020","journal-title":"Neural Regen. Res."},{"issue":"10","key":"10.1016\/j.bcp.2022.115122_b1195","doi-asserted-by":"crossref","first-page":"1386","DOI":"10.7150\/ijms.36516","article-title":"Potential for therapeutic use of hydrogen sulfide in oxidative stress-induced neurodegenerative diseases","volume":"16","author":"Tabassum","year":"2019","journal-title":"Int. J. Med. Sci."},{"issue":"4\u20135","key":"10.1016\/j.bcp.2022.115122_b1200","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1007\/s11064-006-9203-y","article-title":"Redox regulation of cellular stress response in aging and neurodegenerative disorders: role of vitagenes","volume":"32","author":"Calabrese","year":"2007","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.bcp.2022.115122_b1205","doi-asserted-by":"crossref","DOI":"10.3389\/fpsyt.2020.561998","article-title":"Nrf2 activators as dietary phytochemicals against oxidative stress, inflammation, and mitochondrial dysfunction in autism spectrum disorders: a systematic review","volume":"11","author":"Yang","year":"2020","journal-title":"Front. Psychiatry"},{"key":"10.1016\/j.bcp.2022.115122_b1210","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2020.172983","article-title":"The effects of gasotransmitters on bronchopulmonary dysplasia","volume":"873","author":"Lin","year":"2020","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.bcp.2022.115122_b1215","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.coph.2019.07.001","article-title":"Gasotransmitters in health and disease: a mitochondria-centered view","volume":"45","author":"Hendriks","year":"2019","journal-title":"Curr. Opin. Pharmacol."},{"issue":"3","key":"10.1016\/j.bcp.2022.115122_b1220","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/j.mehy.2012.05.016","article-title":"Nrf2 as a converging node for cellular signaling pathways of gasotransmitters","volume":"79","author":"Liu","year":"2012","journal-title":"Med. Hypothes."},{"issue":"1","key":"10.1016\/j.bcp.2022.115122_b1225","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.freeradbiomed.2011.03.039","article-title":"Nitric oxide activates an Nrf2\/sulfiredoxin antioxidant pathway in macrophages","volume":"51","author":"Abbas","year":"2011","journal-title":"Free Radical. Bio. Med."},{"issue":"4","key":"10.1016\/j.bcp.2022.115122_b1230","doi-asserted-by":"crossref","DOI":"10.1152\/ajpcell.00643.2008","article-title":"Nitric oxide-mediated protection of endothelial cells from hydrogen peroxide is mediated by intracellular zinc and glutathione","volume":"296","author":"Cortese-Krott","year":"2009","journal-title":"Am. J. Physiol.-Cell Ph."},{"issue":"2","key":"10.1016\/j.bcp.2022.115122_b1235","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/j.cardiores.2007.03.004","article-title":"Nitric oxide stimulates heme oxygenase-1 gene transcription via the Nrf2\/ARE complex to promote vascular smooth muscle cell survival","volume":"75","author":"Liu","year":"2007","journal-title":"Cardiovasc. Res."},{"issue":"11","key":"10.1016\/j.bcp.2022.115122_b1240","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.1161\/01.RES.0000338597.71702.ad","article-title":"Heme oxygenase-1 regulates cardiac mitochondrial biogenesis via Nrf2-mediated transcriptional control of nuclear respiratory factor-1","volume":"103","author":"Piantadosi","year":"2008","journal-title":"Circ. Res."},{"issue":"7","key":"10.1016\/j.bcp.2022.115122_b1245","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1096\/fj.03-0643fje","article-title":"Carbon monoxide protection against endotoxic shock involves reciprocal effects on iNOS in the lung and liver","volume":"18","author":"Sarady","year":"2004","journal-title":"FASEB J."},{"issue":"11","key":"10.1016\/j.bcp.2022.115122_b1250","doi-asserted-by":"crossref","first-page":"1707","DOI":"10.1084\/jem.20031003","article-title":"Carbon monoxide protects against liver failure through nitric oxide-induced heme oxygenase 1","volume":"198","author":"Zuckerbraun","year":"2003","journal-title":"J. Exp. Med."},{"issue":"2","key":"10.1016\/j.bcp.2022.115122_b1255","doi-asserted-by":"crossref","first-page":"e12686","DOI":"10.1111\/jne.12686","article-title":"Nitric oxide acutely modulates hypothalamic and neurohypophyseal carbon monoxide and hydrogen sulphide production to control vasopressin, oxytocin and atrial natriuretic peptide release in rats","volume":"31","author":"Coletti","year":"2019","journal-title":"J. Neuroendocrinol."},{"issue":"9","key":"10.1016\/j.bcp.2022.115122_b1260","doi-asserted-by":"crossref","first-page":"2109","DOI":"10.1084\/jem.20052267","article-title":"Carbon monoxide reverses established pulmonary hypertension","volume":"203","author":"Zuckerbraun","year":"2006","journal-title":"J. Exp. Med."},{"issue":"4","key":"10.1016\/j.bcp.2022.115122_b1265","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1161\/CIRCULATIONAHA.109.887695","article-title":"Nitric oxide-dependent bone marrow progenitor mobilization by carbon monoxide enhances endothelial repair after vascular injury","volume":"121","author":"Wegiel","year":"2010","journal-title":"Circulation"},{"issue":"7","key":"10.1016\/j.bcp.2022.115122_b1270","doi-asserted-by":"crossref","first-page":"5052","DOI":"10.1002\/jcp.30214","article-title":"Hydrogen sulfide restores sevoflurane postconditioning mediated cardioprotection in diabetic rats: Role of SIRT1\/Nrf2 signaling-modulated mitochondrial dysfunction and oxidative stress","volume":"236","author":"Zhang","year":"2021","journal-title":"J. Cell. Physiol."},{"issue":"5","key":"10.1016\/j.bcp.2022.115122_b1275","doi-asserted-by":"crossref","first-page":"H1723","DOI":"10.1152\/ajpheart.00553.2011","article-title":"Pathophysiology of myocardial reperfusion injury: preconditioning, postconditioning, and translational aspects of protective measures","volume":"301","author":"Sanada","year":"2011","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"issue":"1","key":"10.1016\/j.bcp.2022.115122_b1280","doi-asserted-by":"crossref","DOI":"10.3390\/ijms22010047","article-title":"Therapeutic potential of Carbon Monoxide (CO) and Hydrogen Sulfide (H2S) in hemolytic and hemorrhagic vascular disorders-interaction between the heme oxygenase and H2S-producing systems","volume":"22","author":"Gall","year":"2020","journal-title":"Int. J. Mol. Sci."},{"issue":"5","key":"10.1016\/j.bcp.2022.115122_b1285","doi-asserted-by":"crossref","first-page":"2507","DOI":"10.21873\/invivo.12067","article-title":"Hydrogen sulphide and nitric oxide cooperate in cardioprotection against ischemia\/reperfusion injury in isolated rat heart","volume":"34","author":"Ustunova","year":"2020","journal-title":"In Vivo"},{"issue":"6","key":"10.1016\/j.bcp.2022.115122_b1290","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1124\/mol.117.109645","article-title":"Hydrogen sulfide preserves endothelial nitric oxide synthase function by inhibiting proline-rich kinase 2: implications for cardiomyocyte survival and cardioprotection","volume":"92","author":"Bibli","year":"2017","journal-title":"Mol. Pharmacol."},{"issue":"13","key":"10.1016\/j.bcp.2022.115122_b1295","doi-asserted-by":"crossref","first-page":"1792","DOI":"10.1096\/fj.02-0211hyp","article-title":"Two's company, three's a crowd: can H2S be the third endogenous gaseous transmitter?","volume":"16","author":"Wang","year":"2002","journal-title":"FASEB J."},{"issue":"1","key":"10.1016\/j.bcp.2022.115122_b1300","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1002\/hep.22604","article-title":"Cystathionine beta-synthase as a carbon monoxide-sensitive regulator of bile excretion","volume":"49","author":"Shintani","year":"2009","journal-title":"Hepatology"},{"issue":"4","key":"10.1016\/j.bcp.2022.115122_b1305","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/S0162-0134(01)00335-X","article-title":"Characterization of NO binding to human cystathionine beta-synthase: possible implications of the effects of CO and NO binding to the human enzyme","volume":"87","author":"Taoka","year":"2001","journal-title":"J. Inorg. Biochem."},{"key":"10.1016\/j.bcp.2022.115122_b1310","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/j.freeradbiomed.2016.08.025","article-title":"Cystathionine beta-synthase and PGRMC1 as CO sensors","volume":"99","author":"Kabe","year":"2016","journal-title":"Free Radic. Biol. Med."},{"issue":"7","key":"10.1016\/j.bcp.2022.115122_b1315","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1164\/rccm.201204-0688OC","article-title":"Carbon monoxide induces cardiac arrhythmia via induction of the late Na+ current","volume":"186","author":"Dallas","year":"2012","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.bcp.2022.115122_b1320","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1186\/1744-8069-5-44","article-title":"The endogenous hydrogen sulfide producing enzyme cystathionine-beta synthase contributes to visceral hypersensitivity in a rat model of irritable bowel syndrome","volume":"5","author":"Xu","year":"2009","journal-title":"Mol Pain"},{"issue":"14","key":"10.1016\/j.bcp.2022.115122_b1325","doi-asserted-by":"crossref","first-page":"4070","DOI":"10.1096\/fj.07-8669com","article-title":"Hydrogen sulfide enhances ulcer healing in rats","volume":"21","author":"Wallace","year":"2007","journal-title":"FASEB J."},{"issue":"6","key":"10.1016\/j.bcp.2022.115122_b1330","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1096\/fj.04-3023fje","article-title":"Role of hydrogen sulfide in acute pancreatitis and associated lung injury","volume":"19","author":"Bhatia","year":"2005","journal-title":"FASEB J."},{"issue":"5","key":"10.1016\/j.bcp.2022.115122_b1335","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1113\/jphysiol.2013.266841","article-title":"Effect of endogenous hydrogen sulfide on the transwall gradient of the mouse colon circular smooth muscle","volume":"592","author":"Sha","year":"2014","journal-title":"J. Physiol."},{"key":"10.1016\/j.bcp.2022.115122_b1340","doi-asserted-by":"crossref","first-page":"104","DOI":"10.3389\/fphys.2011.00104","article-title":"Hydrogen sulfide increases nitric oxide production from endothelial cells by an akt-dependent mechanism","volume":"2","author":"Predmore","year":"2011","journal-title":"Front. Physiol.."},{"issue":"Pt 5","key":"10.1016\/j.bcp.2022.115122_b1345","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1042\/BST0351138","article-title":"An overview of the biological significance of endogenous gases: new roles for old molecules","volume":"35","author":"Li","year":"2007","journal-title":"Biochem. Soc. Trans."},{"key":"10.1016\/j.bcp.2022.115122_b1350","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.niox.2013.07.002","article-title":"Hydrogen sulfide chemical biology: pathophysiological roles and detection","volume":"35","author":"Kolluru","year":"2013","journal-title":"Nitric Oxide"},{"issue":"11","key":"10.1016\/j.bcp.2022.115122_b1355","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1042\/CS20110267","article-title":"Emerging role of hydrogen sulfide in health and disease: critical appraisal of biomarkers and pharmacological tools","volume":"121","author":"Whiteman","year":"2011","journal-title":"Clin. Sci. (Lond.)"},{"issue":"11","key":"10.1016\/j.bcp.2022.115122_b1360","doi-asserted-by":"crossref","first-page":"2081","DOI":"10.1089\/ars.2010.3572","article-title":"Regulation of heart function by endogenous gaseous mediators-crosstalk between nitric oxide and hydrogen sulfide","volume":"14","author":"Yong","year":"2011","journal-title":"Antioxid. Redox Signal"},{"issue":"1","key":"10.1016\/j.bcp.2022.115122_b1365","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.bbrc.2006.02.154","article-title":"Evidence for the formation of a novel nitrosothiol from the gaseous mediators nitric oxide and hydrogen sulphide","volume":"343","author":"Whiteman","year":"2006","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"1","key":"10.1016\/j.bcp.2022.115122_b1370","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.bbrc.2004.02.176","article-title":"Impact of hydrogen sulfide on carbon monoxide\/heme oxygenase pathway in the pathogenesis of hypoxic pulmonary hypertension","volume":"317","author":"Qingyou","year":"2004","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"12","key":"10.1016\/j.bcp.2022.115122_b1375","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.1111\/j.1745-7254.2006.00425.x","article-title":"Interaction between hydrogen sulfide\/cystathionine gamma-lyase and carbon monoxide\/heme oxygenase pathways in aortic smooth muscle cells","volume":"27","author":"Jin","year":"2006","journal-title":"Acta Pharmacol. Sin."},{"issue":"2","key":"10.1016\/j.bcp.2022.115122_b1380","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1016\/j.bbrc.2006.04.162","article-title":"Impact of L-arginine on hydrogen sulfide\/cystathionine-gamma-lyase pathway in rats with high blood flow-induced pulmonary hypertension","volume":"345","author":"Yanfei","year":"2006","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"5","key":"10.1016\/j.bcp.2022.115122_b1385","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1038\/bjp.2008.296","article-title":"Biosynthesis of H2S is impaired in non-obese diabetic (NOD) mice","volume":"155","author":"Brancaleone","year":"2008","journal-title":"Br. J. Pharmacol."},{"issue":"3","key":"10.1016\/j.bcp.2022.115122_b1390","doi-asserted-by":"crossref","first-page":"e0121621","DOI":"10.1371\/journal.pone.0121621","article-title":"Interactions of the gasotransmitters contribute to microvascular tone (dys)regulation in the preterm neonate","volume":"10","author":"Dyson","year":"2015","journal-title":"PLoS ONE"},{"issue":"4","key":"10.1016\/j.bcp.2022.115122_b1395","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1161\/HYPERTENSIONAHA.113.01625","article-title":"Gasotransmitters: a solution for the therapeutic dilemma in preeclampsia?","volume":"62","author":"Holwerda","year":"2013","journal-title":"Hypertension"},{"key":"10.1016\/j.bcp.2022.115122_b1400","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1179\/135100006X154978","article-title":"Bilirubin: an endogenous scavenger of nitric oxide and reactive nitrogen species","volume":"11","author":"Mancuso","year":"2006","journal-title":"Redox. Rep."},{"key":"10.1016\/j.bcp.2022.115122_b1405","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1002\/biof.22","article-title":"Vitagenes, cellular stress response and acetylcarnitine: relevance to hormesis","volume":"35","author":"Calabrese","year":"2009","journal-title":"BioFactors"},{"key":"10.1016\/j.bcp.2022.115122_b1410","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.arr.2017.12.004","article-title":"Poor cognitive ageing: vulnerabilities, mechanisms and the impact of nutritional interventions","volume":"42","author":"Miquel","year":"2018","journal-title":"Ageing Res. Rev."},{"issue":"74","key":"10.1016\/j.bcp.2022.115122_b1415","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1002\/jnr.10810","article-title":"Elevation of mitochondrial glutathione by gamma-glutamylcysteine ethyl ester protects mitochondria against peroxynitrite-induced oxidative stress","volume":"15","author":"Drake","year":"2003","journal-title":"J. Neurosci.. Res."},{"key":"10.1016\/j.bcp.2022.115122_b1420","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1007\/s10522-012-9374-7","article-title":"Hormesis: why it is important to biogerontologists","volume":"13","author":"Calabrese","year":"2012","journal-title":"Biogerontology"},{"key":"10.1016\/j.bcp.2022.115122_b1425","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1002\/biof.22","article-title":"Vitagenes, cellular stress response, and acetylcarnitine: relevance to hormesis","volume":"35","author":"Calabrese","year":"2009","journal-title":"BioFactorsVolume"},{"key":"10.1016\/j.bcp.2022.115122_bib1426","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1016\/j.chembiol.2011.09.008","article-title":"HSF1-dependent upregulation of Hsp70 by sulfhydryl-reactive inducers of the KEAP1\/NRF2\/ARE pathway","volume":"18","author":"Zhang","year":"2011","journal-title":". Chem Biol."}],"container-title":["Biochemical Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006295222002167?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006295222002167?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T13:38:35Z","timestamp":1757770715000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006295222002167"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8]]},"references-count":286,"alternative-id":["S0006295222002167"],"URL":"https:\/\/doi.org\/10.1016\/j.bcp.2022.115122","relation":{},"ISSN":["0006-2952"],"issn-type":[{"value":"0006-2952","type":"print"}],"subject":[],"published":{"date-parts":[[2022,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"NO, CO and H2S: A trinacrium of bioactive gases in the brain","name":"articletitle","label":"Article Title"},{"value":"Biochemical Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bcp.2022.115122","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"115122"}}