{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T14:06:52Z","timestamp":1791986812403,"version":"4.4.0"},"reference-count":37,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical Pharmacology"],"published-print":{"date-parts":[[2024,11]]},"DOI":"10.1016\/j.bcp.2024.116467","type":"journal-article","created":{"date-parts":[[2024,8,5]],"date-time":"2024-08-05T23:34:09Z","timestamp":1722900849000},"page":"116467","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["Synergistic effects of resveratrol and enzyme replacement therapy in the Mucopolysaccharidosis type I"],"prefix":"10.1016","volume":"229","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4941-766X","authenticated-orcid":false,"given":"Estera","family":"Rintz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maja","family":"Ziemian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Kobus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lidia","family":"Gaffke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karolina","family":"Pierzynowska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grzegorz","family":"Wegrzyn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"24","key":"10.1016\/j.bcp.2024.116467_b0005","doi-asserted-by":"crossref","first-page":"476","DOI":"10.21037\/atm.2018.11.39","article-title":"Lysosomal storage disease overview","volume":"6","author":"Sun","year":"2018","journal-title":"Ann. Transl. Med."},{"key":"10.1016\/j.bcp.2024.116467_b0010","article-title":"Glycosaminoglycan Storage Disorders: A Review","author":"Alaniz","year":"2012","journal-title":"Biochem. Res. Int."},{"issue":"1","key":"10.1016\/j.bcp.2024.116467_b0015","doi-asserted-by":"crossref","first-page":"1","DOI":"10.5582\/irdr.2020.01011","article-title":"A basic understanding of mucopolysaccharidosis: Incidence, clinical features, diagnosis, and management","volume":"9","author":"Zhou","year":"2020","journal-title":"Intractable Rare Dis. Res."},{"issue":"10","key":"10.1016\/j.bcp.2024.116467_b0020","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1136\/jmedgenet-2021-108061","article-title":"Novel subtype of mucopolysaccharidosis caused by arylsulfatase K (ARSK) deficiency","volume":"59","author":"Verheyen","year":"2022","journal-title":"J. Med. Genet."},{"issue":"8","key":"10.1016\/j.bcp.2024.116467_b0025","doi-asserted-by":"crossref","first-page":"1838","DOI":"10.3390\/cells9081838","article-title":"Mucopolysaccharidosis type I: a review of the natural history and molecular pathology","volume":"9","author":"Hampe","year":"2020","journal-title":"Cells."},{"issue":"12","key":"10.1016\/j.bcp.2024.116467_b0030","doi-asserted-by":"crossref","first-page":"2425","DOI":"10.1002\/ajmg.a.61378","article-title":"Guffon, N, Growth patterns for untreated individuals with MPS I: report from the international MPS I registry","volume":"179","author":"Viskochil","year":"2019","journal-title":"Am. J. Med. Genet. A"},{"key":"10.1016\/j.bcp.2024.116467_b0035","unstructured":"Clarke, L.A, Mucopolysaccharidosis Type I. 2002 [updated 2021]. In: Adam, M.P., Feldman, J., Mirzaa, G.M., Pagon, R.A., Wallace, S.E., Bean, L.J.H., Gripp, K.W., Amemiya, A., editors, GeneReviews\u00ae [Internet]. Seattle (WA): University of Washington, Seattle; 1993\u20132023. PMID: 20301341."},{"issue":"2","key":"10.1016\/j.bcp.2024.116467_b0040","doi-asserted-by":"crossref","first-page":"209","DOI":"10.3390\/metabo13020209","article-title":"Mucopolysaccharidosis type 1 among children\u2014neuroradiological perspective based on single centre experience and literature review","volume":"13","author":"Machnikowska-Soko\u0142owska","year":"2023","journal-title":"Metabolites"},{"issue":"1","key":"10.1016\/j.bcp.2024.116467_b0045","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1186\/s13023-017-0662-9","article-title":"Open issues in Mucopolysaccharidosis type I-Hurler","volume":"12","author":"Parini","year":"2017","journal-title":"Orphanet J. Rare Dis."},{"issue":"15","key":"10.1016\/j.bcp.2024.116467_b0050","doi-asserted-by":"crossref","first-page":"7888","DOI":"10.3390\/ijms22157888","article-title":"Differences in MPS I and MPS II disease manifestations","volume":"22","author":"Hampe","year":"2021","journal-title":"Int. J. Mol. Sci."},{"issue":"8249","key":"10.1016\/j.bcp.2024.116467_b0055","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1016\/S0140-6736(81)91046-1","article-title":"Reversal of clinical features of Hurler's disease and biochemical improvement after treatment by bone-marrow transplantation","volume":"2","author":"Hobbs","year":"1981","journal-title":"Lancet"},{"issue":"11","key":"10.1016\/j.bcp.2024.116467_b0060","doi-asserted-by":"crossref","first-page":"4894","DOI":"10.1182\/blood.V87.11.4894.bloodjournal87114894","article-title":"Outcome of unrelated donor bone marrow transplantation in 40 children with Hurler syndrome","volume":"87","author":"Peters","year":"1996","journal-title":"Blood"},{"key":"10.1016\/j.bcp.2024.116467_b0065","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2020.173534","article-title":"Has resveratrol a potential for mucopolysaccharidosis treatment?","volume":"888","author":"Rintz","year":"2020","journal-title":"Eur. J. Pharmacol."},{"issue":"Suppl 1","key":"10.1016\/j.bcp.2024.116467_b0070","doi-asserted-by":"crossref","first-page":"S10","DOI":"10.1016\/j.pedneo.2022.10.001","article-title":"Current and new therapies for mucopolysaccharidoses","volume":"64","author":"Penon-Portmann","year":"2023","journal-title":"Pediatr. Neonatol."},{"issue":"1","key":"10.1016\/j.bcp.2024.116467_b0075","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1007\/s13311-022-01323-7","article-title":"Activities of (Poly)phenolic antioxidants and other natural autophagy modulators in the treatment of sanfilippo disease: remarkable efficacy of resveratrol in cellular and animal models","volume":"20","author":"Rintz","year":"2023","journal-title":"Neurotherapeutics"},{"key":"10.1016\/j.bcp.2024.116467_b0080","first-page":"747","article-title":"Therapeutic potential of lithium chloride and valproic acid against neuronopathic types of mucopolysaccharidoses through induction of the autophagy process","volume":"1","author":"Gaffke","year":"2023","journal-title":"Arch. Biochem. Biophys."},{"issue":"2","key":"10.1016\/j.bcp.2024.116467_b0085","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.ymgme.2013.11.009","article-title":"Standardization of \u03b1-L-iduronidase enzyme assay with Michaelis-Menten kinetics","volume":"111","author":"Ou","year":"2014","journal-title":"Mol. Genet. Metab."},{"key":"10.1016\/j.bcp.2024.116467_b0090","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.bbrc.2023.04.093","article-title":"Contribution of vesicle trafficking dysregulation to the pathomechanism of mucopolysaccharidosis","volume":"665","author":"Gaffke","year":"2023","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"1","key":"10.1016\/j.bcp.2024.116467_b0095","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1172\/JCI112262","article-title":"Trafficking of lysosomal enzymes in normal and disease states","volume":"77","author":"Kornfeld","year":"1986","journal-title":"J. Clin. Invest."},{"issue":"5","key":"10.1016\/j.bcp.2024.116467_b0100","doi-asserted-by":"crossref","DOI":"10.1042\/BSR20211856","article-title":"Mechanisms regulating the sorting of soluble lysosomal proteins","volume":"42","author":"Mera\u015f","year":"2022","journal-title":"Biosci. Rep."},{"issue":"1","key":"10.1016\/j.bcp.2024.116467_b0105","doi-asserted-by":"crossref","first-page":"9","DOI":"10.2174\/1872214808666140115111350","article-title":"Treatment of lysosomal storage diseases: recent patents and future strategies","volume":"8","author":"Ortolano","year":"2014","journal-title":"Recent Pat. Endocr. Metab. Immune Drug Discov."},{"issue":"1","key":"10.1016\/j.bcp.2024.116467_b0110","doi-asserted-by":"crossref","first-page":"477","DOI":"10.3390\/ijms24010477","article-title":"Mucopolysaccharidoses: cellular consequences of glycosaminoglycans accumulation and potential targets","volume":"24","author":"Leal","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.bcp.2024.116467_b0115","article-title":"The role of lysosomal membrane proteins in autophagy and related diseases","author":"Xu","year":"2023","journal-title":"FEBS J."},{"key":"10.1016\/j.bcp.2024.116467_b0120","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1038\/s41421-020-0141-7","article-title":"Lysosome biology in autophagy","volume":"6","author":"Yim","year":"2020","journal-title":"Cell Discov."},{"issue":"6","key":"10.1016\/j.bcp.2024.116467_b0125","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1042\/EBC20170055","article-title":"Dysregulation of autophagy as a common mechanism in lysosomal storage diseases","volume":"61","author":"Seranova","year":"2017","journal-title":"Essays Biochem."},{"issue":"1","key":"10.1016\/j.bcp.2024.116467_b0130","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1247\/csf.23.33","article-title":"Bafilomycin A1 prevents maturation of autophagic vacuoles by inhibiting fusion between autophagosomes and lysosomes in rat hepatoma cell line, H-4-II-E cells","volume":"23","author":"Yamamoto","year":"1998","journal-title":"Cell Struct. Funct."},{"issue":"2","key":"10.1016\/j.bcp.2024.116467_b0135","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.3892\/mmr.2014.2281","article-title":"Bafilomycin A1 inhibits autophagy and induces apoptosis in MG63 osteosarcoma cells","volume":"10","author":"Xie","year":"2014","journal-title":"Mol. Med. Rep."},{"issue":"4","key":"10.1016\/j.bcp.2024.116467_b0140","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1083\/jcb.200507002","article-title":"p62\/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death","volume":"171","author":"Bj\u00f8rk\u00f8y","year":"2005","journal-title":"J. Cell Biol."},{"issue":"1","key":"10.1016\/j.bcp.2024.116467_b0145","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/S0002-9440(10)64369-6","article-title":"p62 Is a common component of cytoplasmic inclusions in protein aggregation diseases","volume":"160","author":"Zatloukal","year":"2002","journal-title":"Am. J. Pathol."},{"issue":"1","key":"10.1016\/j.bcp.2024.116467_b0150","first-page":"S10","article-title":"Current and new therapies for mucopolysaccharidoses","volume":"64","author":"Penon-Portmann","year":"2023","journal-title":"PEDN"},{"issue":"1","key":"10.1016\/j.bcp.2024.116467_b0155","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1007\/s12017-019-08559-1","article-title":"Mucopolysaccharidosis and autophagy: controversies on the contribution of the process to the pathogenesis and possible therapeutic applications","volume":"22","author":"Pierzynowska","year":"2020","journal-title":"NeuroMol. Med."},{"issue":"4","key":"10.1016\/j.bcp.2024.116467_b0160","first-page":"383","article-title":"Autofagia \u2013 proces o dw\u00f3ch obliczach","volume":"44","author":"Dere\u0144-Wagemann","year":"2013","journal-title":"AHP"},{"issue":"1","key":"10.1016\/j.bcp.2024.116467_b0165","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/15548627.2020.1797280","article-title":"Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1","volume":"17","author":"Klionsky","year":"2021","journal-title":"Autophagy"},{"issue":"3","key":"10.1016\/j.bcp.2024.116467_b0170","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.3390\/ijms21031156","article-title":"Genetic base of behavioral disorders in mucopolysaccharidoses: transcriptomic studies","volume":"21","author":"Pierzynowska","year":"2020","journal-title":"Int. J. Mol. Sci."},{"issue":"9","key":"10.1016\/j.bcp.2024.116467_b0175","doi-asserted-by":"crossref","first-page":"3194","DOI":"10.3390\/ijms21093194","article-title":"Transcriptomic changes related to cellular processes with particular emphasis on cell activation in lysosomal storage diseases from the group of mucopolysaccharidoses","volume":"21","author":"Rintz","year":"2020","journal-title":"Int. J. Mol. Sci."},{"issue":"4","key":"10.1016\/j.bcp.2024.116467_b0180","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.3390\/ijms21041204","article-title":"Underestimated aspect of mucopolysaccharidosis pathogenesis: global changes in cellular processes revealed by transcriptomic studies","volume":"21","author":"Gaffke","year":"2020","journal-title":"Int. J. Mol. Sci."},{"issue":"12","key":"10.1016\/j.bcp.2024.116467_b0185","doi-asserted-by":"crossref","first-page":"e14192","DOI":"10.1371\/journal.pone.0014192","article-title":"Genistein improves neuropathology and corrects behaviour in a mouse model of neurodegenerative metabolic disease","volume":"5","author":"Malinowska","year":"2010","journal-title":"PLoS One"}],"container-title":["Biochemical Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006295224004507?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006295224004507?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,3,11]],"date-time":"2025-03-11T17:15:07Z","timestamp":1741713307000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006295224004507"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11]]},"references-count":37,"alternative-id":["S0006295224004507"],"URL":"https:\/\/doi.org\/10.1016\/j.bcp.2024.116467","relation":{},"ISSN":["0006-2952"],"issn-type":[{"value":"0006-2952","type":"print"}],"subject":[],"published":{"date-parts":[[2024,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Synergistic effects of resveratrol and enzyme replacement therapy in the Mucopolysaccharidosis type I","name":"articletitle","label":"Article Title"},{"value":"Biochemical Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bcp.2024.116467","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"116467"}}