{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T19:21:45Z","timestamp":1784661705792,"version":"3.55.0"},"reference-count":56,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100003392","name":"Natural Science Foundation of Fujian Province","doi-asserted-by":"publisher","award":["2022J011050"],"award-info":[{"award-number":["2022J011050"]}],"id":[{"id":"10.13039\/501100003392","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical Pharmacology"],"published-print":{"date-parts":[[2025,10]]},"DOI":"10.1016\/j.bcp.2025.117106","type":"journal-article","created":{"date-parts":[[2025,7,4]],"date-time":"2025-07-04T12:49:47Z","timestamp":1751633387000},"page":"117106","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["CircCHAF1A induced cellular senescence by enhancing the stability of p21 to suppress gastric cancer progression"],"prefix":"10.1016","volume":"240","author":[{"given":"Jingfu","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xianren","family":"Ye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.bcp.2025.117106_b0005","first-page":"229","article-title":"Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"74","author":"Bray","year":"2024","journal-title":"CA Cancer J. Clin."},{"issue":"1","key":"10.1016\/j.bcp.2025.117106_b0010","doi-asserted-by":"crossref","first-page":"1763","DOI":"10.1186\/s12889-024-19104-6","article-title":"Global incidence and mortality trends of gastric cancer and predicted mortality of gastric cancer by 2035","volume":"24","author":"Lin","year":"2024","journal-title":"BMC Public Health"},{"issue":"1","key":"10.1016\/j.bcp.2025.117106_b0015","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1186\/s10020-025-01075-y","article-title":"Targeted therapy and immunotherapy for gastric cancer: rational strategies, novel advancements, challenges, and future perspectives","volume":"31","author":"Luo","year":"2025","journal-title":"Mol. Med."},{"key":"10.1016\/j.bcp.2025.117106_b0020","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.semcancer.2025.02.002","article-title":"Reshaping the immune microenvironment and reversing immunosenescence by natural products: prospects for immunotherapy in gastric cancer","volume":"110","author":"Cao","year":"2025","journal-title":"Semin. Cancer Biol."},{"key":"10.1016\/j.bcp.2025.117106_b0025","doi-asserted-by":"crossref","first-page":"45","DOI":"10.2147\/CLEP.S442152","article-title":"Cancer survival trends in Southeastern China, 2011-2021: a population-based study","volume":"16","author":"Zhou","year":"2024","journal-title":"Clin. Epidemiol."},{"issue":"4","key":"10.1016\/j.bcp.2025.117106_b0030","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1124\/pharmrev.122.000622","article-title":"Cellular senescence: from mechanisms to current biomarkers and senotherapies","volume":"75","author":"Lucas","year":"2023","journal-title":"Pharmacol. Rev."},{"issue":"2","key":"10.1016\/j.bcp.2025.117106_b0035","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1038\/s41580-020-00314-w","article-title":"Cellular senescence in ageing: from mechanisms to therapeutic opportunities","volume":"22","author":"Di Micco","year":"2021","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"2","key":"10.1016\/j.bcp.2025.117106_b0040","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1158\/2159-8290.CD-22-0523","article-title":"Cellular senescence is immunogenic and promotes antitumor immunity","volume":"13","author":"Marin","year":"2023","journal-title":"Cancer Discov."},{"issue":"1","key":"10.1016\/j.bcp.2025.117106_b0045","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1186\/s12943-024-02096-7","article-title":"Cellular senescence and SASP in tumor progression and therapeutic opportunities","volume":"23","author":"Dong","year":"2024","journal-title":"Mol. Cancer"},{"issue":"6","key":"10.1016\/j.bcp.2025.117106_b0050","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1111\/acel.12138","article-title":"Chemokine receptor CXCR2 is transactivated by p53 and induces p38-mediated cellular senescence in response to DNA damage","volume":"12","author":"Guo","year":"2013","journal-title":"Aging Cell"},{"issue":"7","key":"10.1016\/j.bcp.2025.117106_b0055","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1016\/j.ccell.2023.05.006","article-title":"Senescent alveolar macrophages promote early-stage lung tumorigenesis","volume":"41","author":"Prieto","year":"2023","journal-title":"Cancer Cell"},{"issue":"1","key":"10.1016\/j.bcp.2025.117106_b0060","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1186\/s12967-025-06115-z","article-title":"A novel peptide encoded by circSRCAP confers resistance to enzalutamide by inhibiting the ubiquitin-dependent degradation of AR-V7 in castration-resistant prostate cancer","volume":"23","author":"Meng","year":"2025","journal-title":"J. Transl. Med."},{"key":"10.1016\/j.bcp.2025.117106_b0065","doi-asserted-by":"crossref","DOI":"10.1016\/j.canlet.2025.217470","article-title":"circCCNY enhances lenvatinib sensitivity and suppresses immune evasion in hepatocellular carcinoma by serving as a scaffold for SMURF1 mediated HSP60 degradation","volume":"612","author":"Yang","year":"2025","journal-title":"Cancer Lett."},{"issue":"1","key":"10.1016\/j.bcp.2025.117106_b0070","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1186\/s12885-022-10200-7","article-title":"EIF4A3-induced circBRWD3 promotes tumorigenesis of breast cancer through miR-142-3p_mir-142-5p\/RAC1\/PAK1 signaling","volume":"22","author":"Meng","year":"2022","journal-title":"BMC Cancer"},{"issue":"8","key":"10.1016\/j.bcp.2025.117106_b0075","doi-asserted-by":"crossref","DOI":"10.1111\/jcmm.18217","article-title":"Exosomal circSTRBP from cancer cells facilitates gastric cancer progression via regulating miR-1294\/miR-593-3p\/E2F2 axis","volume":"28","author":"Wang","year":"2024","journal-title":"J. Cell Mol. Med."},{"issue":"1","key":"10.1016\/j.bcp.2025.117106_b0080","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1186\/s12943-024-01966-4","article-title":"Exosome circATP8A1 induces macrophage M2 polarization by regulating the miR-1-3p\/STAT6 axis to promote gastric cancer progression","volume":"23","author":"Deng","year":"2024","journal-title":"Mol. Cancer"},{"issue":"6","key":"10.1016\/j.bcp.2025.117106_b0085","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.1016\/j.jhep.2018.01.012","article-title":"Circular RNA cSMARCA5 inhibits growth and metastasis in hepatocellular carcinoma","volume":"68","author":"Yu","year":"2018","journal-title":"J. Hepatol."},{"key":"10.1016\/j.bcp.2025.117106_b0090","doi-asserted-by":"crossref","DOI":"10.1016\/j.canlet.2023.216247","article-title":"Non-coding RNAs in enzalutamide resistance of castration-resistant prostate cancer","volume":"566","author":"Gao","year":"2023","journal-title":"Cancer Lett."},{"issue":"1","key":"10.1016\/j.bcp.2025.117106_b0095","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1186\/s12935-024-03423-0","article-title":"CircUBA2 promotes the cancer stem cell-like properties of gastric cancer through upregulating STC1 via sponging miR-144-5p","volume":"24","author":"Wang","year":"2024","journal-title":"Cancer Cell Int."},{"key":"10.1016\/j.bcp.2025.117106_b0100","doi-asserted-by":"crossref","DOI":"10.1111\/jipb.13824","article-title":"CircZmMED16 delays plant flowering by negatively regulating starch content through its binding to ZmAPS1","author":"Tang","year":"2025","journal-title":"J. Integr. Plant Biol."},{"key":"10.1016\/j.bcp.2025.117106_b0105","article-title":"A Novel 167-Amino Acid Protein Encoded by CircPCSK6 Inhibits Intrahepatic Cholangiocarcinoma Progression via IKBalpha Ubiquitination","author":"Guan","year":"2025","journal-title":"Adv. Sci. (Weinh.)"},{"issue":"33","key":"10.1016\/j.bcp.2025.117106_b0110","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2012881118","article-title":"CircURI1 interacts with hnRNPM to inhibit metastasis by modulating alternative splicing in gastric cancer","volume":"118","author":"Wang","year":"2021","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"10","key":"10.1016\/j.bcp.2025.117106_b0115","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1038\/s41419-021-04216-3","article-title":"Circular RNA UBE2Q2 promotes malignant progression of gastric cancer by regulating signal transducer and activator of transcription 3-mediated autophagy and glycolysis","volume":"12","author":"Yang","year":"2021","journal-title":"Cell Death Dis."},{"issue":"11","key":"10.1016\/j.bcp.2025.117106_b0120","doi-asserted-by":"crossref","first-page":"4590","DOI":"10.1002\/jcb.29673","article-title":"Identification of downregulated circRNAs from tissue and plasma of patients with gastric cancer and construction of a circRNA-miRNA-mRNA network","volume":"121","author":"Liu","year":"2020","journal-title":"J. Cell. Biochem."},{"issue":"7441","key":"10.1016\/j.bcp.2025.117106_b0125","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1038\/nature11993","article-title":"Natural RNA circles function as efficient microRNA sponges","volume":"495","author":"Hansen","year":"2013","journal-title":"Nature"},{"issue":"1","key":"10.1016\/j.bcp.2025.117106_b0130","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1080\/15476286.2015.1128065","article-title":"CircInteractome: a web tool for exploring circular RNAs and their interacting proteins and microRNAs","volume":"13","author":"Dudekula","year":"2016","journal-title":"RNA Biol."},{"issue":"1","key":"10.1016\/j.bcp.2025.117106_b0135","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1186\/s12951-024-02760-6","article-title":"Circ_0008315 promotes tumorigenesis and cisplatin resistance and acts as a nanotherapeutic target in gastric cancer","volume":"22","author":"Fei","year":"2024","journal-title":"J. Nanobiotechnol."},{"issue":"1","key":"10.1016\/j.bcp.2025.117106_b0140","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1186\/s12967-024-05498-9","article-title":"CircRHBDD1 promotes immune escape via IGF2BP2\/PD-L1 signaling and acts as a nanotherapeutic target in gastric cancer","volume":"22","author":"Li","year":"2024","journal-title":"J. Transl. Med."},{"issue":"18","key":"10.1016\/j.bcp.2025.117106_b0145","doi-asserted-by":"crossref","first-page":"2003","DOI":"10.1080\/15384101.2023.2271341","article-title":"Tumor-derived CircRNA_102191 promotes gastric cancer and facilitates M2 macrophage polarization","volume":"22","author":"Yao","year":"2023","journal-title":"Cell Cycle"},{"issue":"4","key":"10.1016\/j.bcp.2025.117106_b0150","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2024.114111","article-title":"Targeting high circDNA2v levels in colorectal cancer induces cellular senescence and elicits an anti-tumor secretome","volume":"43","author":"Wu","year":"2024","journal-title":"Cell Rep."},{"issue":"1","key":"10.1016\/j.bcp.2025.117106_b0155","doi-asserted-by":"crossref","DOI":"10.1016\/j.yexcr.2024.114390","article-title":"Circular RNA circPFKP suppress gastric cancer progression through targeting miR-346\/CAMD3 axis","volume":"445","author":"Song","year":"2025","journal-title":"Exp. Cell Res."},{"issue":"1","key":"10.1016\/j.bcp.2025.117106_b0160","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1038\/s42003-024-06274-7","article-title":"ALKBH5-mediated m6A modification of circFOXP1 promotes gastric cancer progression by regulating SOX4 expression and sponging miR-338-3p","volume":"7","author":"Wang","year":"2024","journal-title":"Commun. Biol."},{"key":"10.1016\/j.bcp.2025.117106_b0165","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2024.107206","article-title":"CircUGGT2 downregulation by METTL14-dependent m(6)A modification suppresses gastric cancer progression and cisplatin resistance through interaction with miR-186-3p\/MAP3K9 axis","volume":"204","author":"Chen","year":"2024","journal-title":"Pharmacol. Res."},{"issue":"6","key":"10.1016\/j.bcp.2025.117106_b0170","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1111\/odi.12046","article-title":"miR-370 modulates insulin receptor substrate-1 expression and inhibits the tumor phenotypes of oral carcinoma","volume":"19","author":"Chang","year":"2013","journal-title":"Oral Dis."},{"issue":"12","key":"10.1016\/j.bcp.2025.117106_b0175","first-page":"2755","article-title":"Alpinumisoflavone induces apoptosis in esophageal squamous cell carcinoma by modulating miR-370\/PIM1 signaling","volume":"6","author":"Han","year":"2016","journal-title":"Am. J. Cancer Res."},{"issue":"10","key":"10.1016\/j.bcp.2025.117106_b0180","first-page":"2011","article-title":"MiR-370 promotes cell death of liver cancer cells by Akt\/FoxO3a signalling pathway","volume":"20","author":"Sun","year":"2016","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"issue":"3","key":"10.1016\/j.bcp.2025.117106_b0185","doi-asserted-by":"crossref","first-page":"453","DOI":"10.3233\/CBM-171075","article-title":"miR-370 regulates ISG15 expression and influences IFN-alpha sensitivity in hepatocellular carcinoma cells","volume":"22","author":"Liu","year":"2018","journal-title":"Cancer Biomark."},{"key":"10.1016\/j.bcp.2025.117106_b0190","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.omtn.2018.08.010","article-title":"hsa_circ_0061140 knockdown reverses FOXM1-mediated cell growth and metastasis in ovarian cancer through miR-370 sponge activity","volume":"13","author":"Chen","year":"2018","journal-title":"Mol. Ther. Nucleic Acids"},{"issue":"17","key":"10.1016\/j.bcp.2025.117106_b0195","doi-asserted-by":"crossref","first-page":"5042","DOI":"10.7150\/jca.45553","article-title":"The miR-370\/UQCRC2 axis facilitates tumorigenesis by regulating epithelial-mesenchymal transition in Gastric Cancer","volume":"11","author":"Wang","year":"2020","journal-title":"J. Cancer"},{"issue":"2","key":"10.1016\/j.bcp.2025.117106_b0200","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1038\/onc.2011.226","article-title":"Overexpression of miR-370 and downregulation of its novel target TGFbeta-RII contribute to the progression of gastric carcinoma","volume":"31","author":"Lo","year":"2012","journal-title":"Oncogene"},{"key":"10.1016\/j.bcp.2025.117106_b0205","doi-asserted-by":"crossref","first-page":"13211","DOI":"10.2147\/OTT.S285153","article-title":"Knockdown of circular RNA hsa_circ_0000714 can regulate RAB17 by sponging miR-370-3p to reduce paclitaxel resistance of ovarian cancer through CDK6\/RB pathway","volume":"13","author":"Guo","year":"2020","journal-title":"Oncol. Targets Ther."},{"key":"10.1016\/j.bcp.2025.117106_b0210","doi-asserted-by":"crossref","DOI":"10.1155\/2021\/9394563","article-title":"lncRNA SNHG15 promotes ovarian cancer progression through regulated CDK6 via sponging miR-370-3p","volume":"2021","author":"Wang","year":"2021","journal-title":"Biomed. Res. Int."},{"issue":"2","key":"10.1016\/j.bcp.2025.117106_b0215","doi-asserted-by":"crossref","first-page":"98","DOI":"10.3904\/kjim.2003.18.2.98","article-title":"Prognostic significance of p21 and p53 expression in gastric cancer","volume":"18","author":"Seo","year":"2003","journal-title":"Korean J. Intern. Med."},{"issue":"9","key":"10.1016\/j.bcp.2025.117106_b0220","first-page":"3100","article-title":"Differential expression of metallothionein and p21 in gastric cancer and some precursor lesions","volume":"26","author":"Helal","year":"2022","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"issue":"1","key":"10.1016\/j.bcp.2025.117106_b0225","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1038\/s41388-021-02067-y","article-title":"Complete loss of miR-200 family induces EMT associated cellular senescence in gastric cancer","volume":"41","author":"Yu","year":"2022","journal-title":"Oncogene"},{"key":"10.1016\/j.bcp.2025.117106_b0230","article-title":"Drug-induced senescence by aurora kinase inhibitors attenuates innate immune response of macrophages on gastric cancer organoids","volume":"598","author":"Yang","year":"2024","journal-title":"Cancer Lett."},{"issue":"1","key":"10.1016\/j.bcp.2025.117106_b0235","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1186\/s13046-024-03103-x","article-title":"lncRNA FGD5-AS1 is required for gastric cancer proliferation by inhibiting cell senescence and ROS production via stabilizing YBX1","volume":"43","author":"Qin","year":"2024","journal-title":"J. Exp. Clin. Cancer Res."},{"issue":"11","key":"10.1016\/j.bcp.2025.117106_b0240","doi-asserted-by":"crossref","DOI":"10.1016\/j.tranon.2021.101199","article-title":"Oncosuppressive role of MicroRNA-205-3p in gastric cancer through inhibition of proliferation and induction of senescence: oncosuppressive role of MicroRNA-205 in gastric cancer","volume":"14","author":"Ma","year":"2021","journal-title":"Transl. Oncol."},{"key":"10.1016\/j.bcp.2025.117106_b0245","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2024.1494364","article-title":"AMBRA1 drives gastric cancer progression through regulation of tumor plasticity","volume":"15","author":"Ye","year":"2024","journal-title":"Front. Immunol."},{"issue":"1","key":"10.1016\/j.bcp.2025.117106_b0250","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1038\/s41419-025-07617-w","article-title":"Temozolomide promotes glioblastoma stemness expression through senescence-associated reprogramming via HIF1alpha\/HIF2alpha regulation","volume":"16","author":"Wang","year":"2025","journal-title":"Cell Death Dis."},{"issue":"1","key":"10.1016\/j.bcp.2025.117106_b0255","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1038\/s41421-023-00602-7","article-title":"SGF29 nuclear condensates reinforce cellular aging","volume":"9","author":"Yan","year":"2023","journal-title":"Cell Discov."},{"issue":"7051","key":"10.1016\/j.bcp.2025.117106_b0260","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1038\/nature03890","article-title":"BRAFE600-associated senescence-like cell cycle arrest of human naevi","volume":"436","author":"Michaloglou","year":"2005","journal-title":"Nature"},{"issue":"7051","key":"10.1016\/j.bcp.2025.117106_b0265","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1038\/nature03918","article-title":"Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis","volume":"436","author":"Chen","year":"2005","journal-title":"Nature"},{"issue":"6","key":"10.1016\/j.bcp.2025.117106_b0270","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1038\/s41568-022-00450-9","article-title":"Exploiting senescence for the treatment of cancer","volume":"22","author":"Wang","year":"2022","journal-title":"Nat. Rev. Cancer"},{"issue":"1","key":"10.1016\/j.bcp.2025.117106_b0275","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1038\/s41392-025-02191-1","article-title":"Intranasal prime-boost RNA vaccination elicits potent T cell response for lung cancer therapy","volume":"10","author":"Li","year":"2025","journal-title":"Signal Transduct. Target. Ther."},{"issue":"2","key":"10.1016\/j.bcp.2025.117106_b0280","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1038\/s41551-025-01344-5","article-title":"Small circular RNAs as vaccines for cancer immunotherapy","volume":"9","author":"Zhang","year":"2025","journal-title":"Nat. Biomed. Eng."}],"container-title":["Biochemical Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006295225003715?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006295225003715?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T15:23:33Z","timestamp":1762097013000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006295225003715"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":56,"alternative-id":["S0006295225003715"],"URL":"https:\/\/doi.org\/10.1016\/j.bcp.2025.117106","relation":{},"ISSN":["0006-2952"],"issn-type":[{"value":"0006-2952","type":"print"}],"subject":[],"published":{"date-parts":[[2025,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"CircCHAF1A induced cellular senescence by enhancing the stability of p21 to suppress gastric cancer progression","name":"articletitle","label":"Article Title"},{"value":"Biochemical Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bcp.2025.117106","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"117106"}}