{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T11:43:15Z","timestamp":1784547795203,"version":"3.55.0"},"reference-count":45,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100011645","name":"Kaohsiung Medical University Chung Ho Memorial Hospital","doi-asserted-by":"publisher","award":["KMUH112-2R47"],"award-info":[{"award-number":["KMUH112-2R47"]}],"id":[{"id":"10.13039\/501100011645","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011645","name":"Kaohsiung Medical University Chung Ho Memorial Hospital","doi-asserted-by":"publisher","award":["KMUH 114-4R48"],"award-info":[{"award-number":["KMUH 114-4R48"]}],"id":[{"id":"10.13039\/501100011645","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011645","name":"Kaohsiung Medical University Chung Ho Memorial Hospital","doi-asserted-by":"publisher","award":["KMUH111-1R42"],"award-info":[{"award-number":["KMUH111-1R42"]}],"id":[{"id":"10.13039\/501100011645","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004694","name":"Kaohsiung Medical University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004694","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["108-2314-B-037 -072 -MY3"],"award-info":[{"award-number":["108-2314-B-037 -072 -MY3"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100020595","name":"National Science and Technology Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100020595","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical Pharmacology"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.bcp.2026.117840","type":"journal-article","created":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T16:16:13Z","timestamp":1771604173000},"page":"117840","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Calcitonin gene-related peptide\/protein kinase A: A novel pathway to regulate patency of ductus arteriosus"],"prefix":"10.1016","volume":"248","author":[{"given":"Yen-Hsien","family":"Wu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi-Ching","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ren-Long","family":"Jan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siao-Ping","family":"Tsai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shang-En","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin-Nan","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shih-Hsing","family":"Lo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I-Chen","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zen-Kong","family":"Dai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiunn-Ren","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Hsin","family":"Tseng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jwu-Lai","family":"Yeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2690-7247","authenticated-orcid":false,"given":"Jong-Hau","family":"Hsu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.bcp.2026.117840_b0005","doi-asserted-by":"crossref","DOI":"10.3390\/jcdd11040113","article-title":"Ductus Arteriosus in Fetal and Perinatal Life","volume":"11","author":"Pugnaloni","year":"2024","journal-title":"Journal of Cardiovascular Development and Disease"},{"issue":"2","key":"10.1016\/j.bcp.2026.117840_b0010","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1053\/j.semperi.2011.09.018","article-title":"Mechanisms for ductus arteriosus closure","volume":"36","author":"Coceani","year":"2012","journal-title":"Semin. Perinatol."},{"issue":"1","key":"10.1016\/j.bcp.2026.117840_b0015","doi-asserted-by":"crossref","first-page":"R199","DOI":"10.1152\/ajpregu.00298.2001","article-title":"VEGF regulates remodeling during permanent anatomic closure of the ductus arteriosus","volume":"282","author":"Clyman","year":"2002","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.bcp.2026.117840_b0020","article-title":"Management of Patent Ductus Arteriosus in Premature infants in 2020","volume":"8","author":"Parkerson","year":"2020","journal-title":"Front. Pediatr."},{"issue":"2","key":"10.1016\/j.bcp.2026.117840_b0025","doi-asserted-by":"crossref","first-page":"114","DOI":"10.21037\/tp.2019.04.06","article-title":"Acute therapy of newborns with critical congenital heart disease","volume":"8","author":"Khalil","year":"2019","journal-title":"Translational Pediatrics."},{"issue":"4","key":"10.1016\/j.bcp.2026.117840_b0030","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1515\/jccm-2016-0031","article-title":"Congenital Heart Disease Requiring Maintenance of Ductus Arteriosus in Critically Ill Newborns Admitted at a Tertiary Neonatal Intensive Care Unit","volume":"2","author":"Cucerea","year":"2016","journal-title":"J. Crit. Care Med. (Targu Mures)."},{"issue":"2","key":"10.1016\/j.bcp.2026.117840_b0035","article-title":"Prostaglandin E1 for maintaining ductal patency in neonates with ductal-dependent cardiac lesions","volume":"2","author":"Akkinapally","year":"2018","journal-title":"Cochrane Database Syst. Rev."},{"issue":"6","key":"10.1016\/j.bcp.2026.117840_b0040","doi-asserted-by":"crossref","first-page":"2088","DOI":"10.1016\/j.athoracsur.2020.02.053","article-title":"Effect of long-term Administration of Prostaglandin E(1) on Morphologic changes in Ductus Arteriosus","volume":"110","author":"Iwaki","year":"2020","journal-title":"Ann. Thorac. Surg."},{"issue":"4","key":"10.1016\/j.bcp.2026.117840_b0045","doi-asserted-by":"crossref","first-page":"F608","DOI":"10.1152\/ajprenal.00554.2020","article-title":"The novel STING antagonist H151 ameliorates cisplatin-induced acute kidney injury and mitochondrial dysfunction","volume":"320","author":"Gong","year":"2021","journal-title":"Am. J. Physiol. Renal Physiol."},{"issue":"1","key":"10.1016\/j.bcp.2026.117840_b0050","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1186\/s10194-018-0927-2","article-title":"Migraine induction with calcitonin gene-related peptide in patients from erenumab trials","volume":"19","author":"Christensen","year":"2018","journal-title":"J. Headache Pain"},{"key":"10.1016\/j.bcp.2026.117840_b0055","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.3389\/fphys.2018.01249","article-title":"The Role of Calcitonin Gene Related Peptide (CGRP) in Neurogenic Vasodilation and its Cardioprotective Effects","volume":"9","author":"Kee","year":"2018","journal-title":"Front. Physiol."},{"issue":"9","key":"10.1016\/j.bcp.2026.117840_b0060","article-title":"Efficacy and Safety of Anti-calcitonin Gene-Related Peptide (CGRP) Monoclonal Antibodies in Preventing Migraines: a Systematic Review","volume":"15","author":"Muddam","year":"2023","journal-title":"Cureus"},{"issue":"1","key":"10.1016\/j.bcp.2026.117840_b0065","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1186\/s10194-019-0979-y","article-title":"CGRP and migraine from a cardiovascular point of view: what do we expect from blocking CGRP?","volume":"20","author":"Favoni","year":"2019","journal-title":"J. Headache Pain"},{"issue":"5","key":"10.1016\/j.bcp.2026.117840_b0070","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1536\/ihj.46.867","article-title":"Increased circulating calcitonin gene-related peptide in congestive heart failure caused by congenital heart disease","volume":"46","author":"Hsu","year":"2005","journal-title":"Int. Heart J."},{"issue":"4","key":"10.1016\/j.bcp.2026.117840_b0075","first-page":"5168","article-title":"Involvement of TRPV1 in the expression and release of calcitonin gene-related peptide induced by rutaecarpine","volume":"17","author":"Yang","year":"2018","journal-title":"Mol. Med. Rep."},{"key":"10.1016\/j.bcp.2026.117840_b0080","doi-asserted-by":"crossref","DOI":"10.1016\/j.bcp.2024.116093","article-title":"CGRP attenuates pulmonary vascular remodeling by inhibiting the cGAS-STING-NF\u03baB pathway in pulmonary arterial hypertension","volume":"222","author":"Yan","year":"2024","journal-title":"Biochem. Pharmacol."},{"issue":"2","key":"10.1016\/j.bcp.2026.117840_b0085","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.bbrc.2019.10.064","article-title":"Calcitonin gene-related peptide attenuates angiotensin II-induced ROS-dependent apoptosis in vascular smooth muscle cells by inhibiting the CaMKII\/CREB signalling pathway","volume":"521","author":"Luo","year":"2020","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"1","key":"10.1016\/j.bcp.2026.117840_b0090","doi-asserted-by":"crossref","first-page":"L202","DOI":"10.1152\/ajplung.00064.2004","article-title":"Antiproliferative effects of calcitonin gene-related peptide in aortic and pulmonary artery smooth muscle cells, American journal of physiology","volume":"288","author":"Chattergoon","year":"2005","journal-title":"Lung Cellular and Molecular Physiology."},{"key":"10.1016\/j.bcp.2026.117840_b0095","unstructured":"A.V.M. Association, AVMA Guidelines for the Euthanasia of Animals: 2020 Edition, Schaumburg, IL, 2020."},{"key":"10.1016\/j.bcp.2026.117840_b0100","doi-asserted-by":"crossref","unstructured":"J.L. Yeh, J.R. Wu, B.N. Wu, S.F. Yang, Z.K. Dai, S.F. Liou, et al., B-type natriuretic peptide prevents postnatal closure of ductus arteriosus by both vasodilation and anti-remodeling in neonatal rats, Clinical science (London, England : 1979). 132(18) (2018) 2045-2058.","DOI":"10.1042\/CS20180201"},{"issue":"2","key":"10.1016\/j.bcp.2026.117840_b0105","doi-asserted-by":"crossref","DOI":"10.1016\/j.semperi.2023.151715","article-title":"Using omics to breathe new life into our understanding of the ductus arteriosus oxygen response","volume":"47","author":"Bentley","year":"2023","journal-title":"Semin. Perinatol."},{"issue":"2","key":"10.1016\/j.bcp.2026.117840_b0110","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1203\/PDR.0b013e31815ed059","article-title":"Developmental absence of the O2 sensitivity of L-type calcium channels in preterm ductus arteriosus smooth muscle cells impairs O2 constriction contributing to patent ductus arteriosus","volume":"63","author":"Th\u00e9baud","year":"2008","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.bcp.2026.117840_b0115","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2024.177106","article-title":"Exendin-4, a glucagon-like peptide-1 receptor agonist, regulates ductus arteriosus by vasodilation and anti-remodeling through the PKA pathway","volume":"985","author":"Liu","year":"2024","journal-title":"Eur. J. Pharmacol."},{"issue":"9","key":"10.1016\/j.bcp.2026.117840_b0120","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.7150\/ijbs.16430","article-title":"Gamma-secretase Inhibitor Prevents Proliferation and Migration of Ductus Arteriosus Smooth Muscle Cells through the Notch3-HES1\/2\/5 Pathway","volume":"12","author":"Wu","year":"2016","journal-title":"Int. J. Biol. Sci."},{"key":"10.1016\/j.bcp.2026.117840_b0125","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2021.661171","article-title":"Cinaciguat Prevents Postnatal Closure of Ductus Arteriosus by Vasodilation and Anti-remodeling in Neonatal Rats","volume":"12","author":"Hung","year":"2021","journal-title":"Front. Physiol."},{"issue":"7","key":"10.1016\/j.bcp.2026.117840_b0130","doi-asserted-by":"crossref","first-page":"1861","DOI":"10.3390\/ijms19071861","article-title":"Molecular Mechanisms for Regulating Postnatal Ductus Arteriosus Closure","volume":"19","author":"Hung","year":"2018","journal-title":"Int. J. Mol. Sci."},{"issue":"1","key":"10.1016\/j.bcp.2026.117840_b0135","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1186\/s10194-023-01644-8","article-title":"Mode and site of action of therapies targeting CGRP signaling","volume":"24","author":"Labastida-Ram\u00edrez","year":"2023","journal-title":"J. Headache Pain"},{"issue":"6","key":"10.1016\/j.bcp.2026.117840_b0140","doi-asserted-by":"crossref","DOI":"10.3390\/ijms22063238","article-title":"Molecular Mechanisms Underlying Remodeling of Ductus Arteriosus: Looking beyond the Prostaglandin Pathway","volume":"22","author":"Hsu","year":"2021","journal-title":"International Journal of Molecular Sciences."},{"issue":"6","key":"10.1016\/j.bcp.2026.117840_b0145","doi-asserted-by":"crossref","first-page":"835","DOI":"10.21037\/tp-20-121","article-title":"Patent ductus arteriosus and oxidative stress in preterm infants: a narrative review","volume":"9","author":"Dani","year":"2020","journal-title":"Translational Pediatrics."},{"issue":"4","key":"10.1016\/j.bcp.2026.117840_b0150","doi-asserted-by":"crossref","DOI":"10.3390\/ijms24043483","article-title":"Mitochondrial Homeostasis in VSMCs as a Central Hub in Vascular Remodeling","volume":"24","author":"Xia","year":"2023","journal-title":"International Journal of Molecular Sciences"},{"issue":"36","key":"10.1016\/j.bcp.2026.117840_b0155","doi-asserted-by":"crossref","first-page":"24025","DOI":"10.1074\/jbc.M109.017061","article-title":"T-type Ca2+ channels promote oxygenation-induced closure of the rat ductus arteriosus not only by vasoconstriction but also by neointima formation","volume":"284","author":"Akaike","year":"2009","journal-title":"J. Biol. Chem."},{"issue":"4","key":"10.1016\/j.bcp.2026.117840_b0160","doi-asserted-by":"crossref","first-page":"H1660","DOI":"10.1152\/ajpheart.00100.2004","article-title":"Multiple transcripts of Ca2+ channel alpha1-subunits and a novel spliced variant of the alpha1C-subunit in rat ductus arteriosus, American journal of physiology","volume":"290","author":"Yokoyama","year":"2006","journal-title":"Heart and Circulatory Physiology"},{"issue":"1","key":"10.1016\/j.bcp.2026.117840_b0165","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1007\/s11033-020-06065-3","article-title":"Calcium-sensing receptor in the development and treatment of pulmonary hypertension","volume":"48","author":"Zhou","year":"2021","journal-title":"Mol. Biol. Rep."},{"issue":"1","key":"10.1016\/j.bcp.2026.117840_b0170","first-page":"1007","article-title":"Calcitonin Gene-Related Peptide Regulates Cardiomyocyte Survival through Regulation of Oxidative stress by PI3K\/Akt and MAPK Signaling Pathways","volume":"2","author":"Umoh","year":"2014","journal-title":"Annals of Clinical and Experimental Hypertension."},{"key":"10.1016\/j.bcp.2026.117840_b0175","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.lfs.2015.11.015","article-title":"Calcitonin gene-related peptide mediates an inflammatory response in Schwann cells via cAMP-dependent ERK signaling cascade","volume":"144","author":"Permpoonputtana","year":"2016","journal-title":"Life Sci."},{"issue":"11","key":"10.1016\/j.bcp.2026.117840_b0180","doi-asserted-by":"crossref","first-page":"2306","DOI":"10.1097\/j.pain.0000000000001337","article-title":"Peripherally administered calcitonin gene-related peptide induces spontaneous pain in mice: implications for migraine","volume":"159","author":"Rea","year":"2018","journal-title":"Pain"},{"issue":"1","key":"10.1016\/j.bcp.2026.117840_b0185","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1038\/s41467-022-28204-z","article-title":"Schwann cell endosome CGRP signals elicit periorbital mechanical allodynia in mice","volume":"13","author":"De Logu","year":"2022","journal-title":"Nat. Commun."},{"issue":"1","key":"10.1016\/j.bcp.2026.117840_b0190","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/S0022-3565(25)20050-7","article-title":"Cardiovascular effects of rat calcitonin gene-related peptide in the conscious rat","volume":"247","author":"Sir\u00e9n","year":"1988","journal-title":"J. Pharmacol. Exp. Ther."},{"issue":"2","key":"10.1016\/j.bcp.2026.117840_b0195","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1161\/01.RES.0000152969.42117.ca","article-title":"Calcitonin gene-related peptide in vivo positive inotropy is attributable to regional sympatho-stimulation and is blunted in congestive heart failure","volume":"96","author":"Katori","year":"2005","journal-title":"Circ. Res."},{"issue":"3","key":"10.1016\/j.bcp.2026.117840_b0200","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1111\/j.1476-5381.1995.tb17179.x","article-title":"Regional haemodynamic effects of human and rat adrenomedullin in conscious rats","volume":"114","author":"Gardiner","year":"1995","journal-title":"Br. J. Pharmacol."},{"issue":"1","key":"10.1016\/j.bcp.2026.117840_b0205","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1080\/10717544.2021.1902021","article-title":"The PLGA nanoparticles for sustainable release of CGRP to ameliorate the inflammatory and vascular disorders in the lung of CGRP-deficient rats","volume":"28","author":"Wang","year":"2021","journal-title":"Drug Deliv."},{"issue":"5","key":"10.1016\/j.bcp.2026.117840_b0210","doi-asserted-by":"crossref","DOI":"10.3390\/biom13050838","article-title":"Research Progress in Calcitonin Gene-Related Peptide and Bone Repair","volume":"13","author":"Wang","year":"2023","journal-title":"Biomolecules"},{"issue":"Pt 11","key":"10.1016\/j.bcp.2026.117840_b0215","doi-asserted-by":"crossref","first-page":"3134","DOI":"10.1093\/brain\/awp168","article-title":"Calcitonin gene-related peptide receptor antagonist olcegepant acts in the spinal trigeminal nucleus","volume":"132","author":"Sixt","year":"2009","journal-title":"Brain J. Neurol."},{"issue":"13","key":"10.1016\/j.bcp.2026.117840_b0220","doi-asserted-by":"crossref","first-page":"2001","DOI":"10.1111\/bph.13799","article-title":"Olcegepant blocks neurogenic and non-neurogenic CGRPergic vasodepressor responses and facilitates noradrenergic vasopressor responses in pithed rats","volume":"174","author":"Avil\u00e9s-Rosas","year":"2017","journal-title":"Br. J. Pharmacol."},{"issue":"1","key":"10.1016\/j.bcp.2026.117840_b0225","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1677\/joe.0.1650133","article-title":"Desensitisation of calcitonin gene-related peptide responsiveness but not adrenomedullin responsiveness in vascular smooth muscle cells","volume":"165","author":"Drake","year":"2000","journal-title":"J. Endocrinol."}],"container-title":["Biochemical Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006295226001711?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006295226001711?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T05:17:49Z","timestamp":1777439869000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006295226001711"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":45,"alternative-id":["S0006295226001711"],"URL":"https:\/\/doi.org\/10.1016\/j.bcp.2026.117840","relation":{},"ISSN":["0006-2952"],"issn-type":[{"value":"0006-2952","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Calcitonin gene-related peptide\/protein kinase A: A novel pathway to regulate patency of ductus arteriosus","name":"articletitle","label":"Article Title"},{"value":"Biochemical Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bcp.2026.117840","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"117840"}}