{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T11:17:39Z","timestamp":1788347859575,"version":"build-2803163510"},"reference-count":57,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100017605","name":"Shaanxi University of Chinese Medicine","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100017605","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical Pharmacology"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1016\/j.bcp.2026.118401","type":"journal-article","created":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:55:16Z","timestamp":1787759716000},"page":"118401","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"P1","title":["Integrin \u03b1V\u03b23-mediated focal adhesion signaling promotes fibroblast activation during renal fibrosis"],"prefix":"10.1016","volume":"254","author":[{"given":"Dongdong","family":"Wu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinrui","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuman","family":"Lei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengcheng","family":"Mu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donglin","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting","family":"Ye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0596-5939","authenticated-orcid":false,"given":"Shouzhu","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bcp.2026.118401_b0005","doi-asserted-by":"crossref","first-page":"6141","DOI":"10.1016\/j.apsb.2025.09.012","article-title":"Emerging epigenetic modifications in renal fibrosis: from mechanisms to treatments","volume":"15","author":"Suo","year":"2025","journal-title":"Acta Pharm. Sin. B"},{"key":"10.1016\/j.bcp.2026.118401_b0010","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1038\/s41392-023-01379-7","article-title":"Kidney fibrosis: from mechanisms to therapeutic medicines","volume":"8","author":"Huang","year":"2023","journal-title":"Signal Transduct. Target. Ther."},{"key":"10.1016\/j.bcp.2026.118401_b0015","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.jconrel.2022.04.004","article-title":"Delivery of sorafenib by myofibroblast-targeted nanoparticles for the treatment of renal fibrosis","volume":"346","author":"Cheng","year":"2022","journal-title":"J. Control. Release"},{"key":"10.1016\/j.bcp.2026.118401_b0020","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1016\/j.kint.2023.03.028","article-title":"Another piece in the puzzle of kidney fibrosis","volume":"103","author":"Remuzzi","year":"2023","journal-title":"Kidney Int."},{"key":"10.1016\/j.bcp.2026.118401_b0025","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1038\/s41581-024-00889-z","article-title":"Metabolism at the crossroads of inflammation and fibrosis in chronic kidney disease","volume":"21","author":"Miguel","year":"2025","journal-title":"Nat. Rev. Nephrol."},{"key":"10.1016\/j.bcp.2026.118401_b0030","first-page":"2187","article-title":"Analysis of structural components of decellularized scaffolds in renal fibrosis","volume":"6","author":"Zhang","year":"2021","journal-title":"Bioact. Mater."},{"key":"10.1016\/j.bcp.2026.118401_b0035","article-title":"The role of the vascular niche in regulating kidney tubulointerstitial fibrosis","author":"Sohail","year":"2025","journal-title":"Kidney Int."},{"key":"10.1016\/j.bcp.2026.118401_b0040","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.kint.2021.02.035","article-title":"Inhibition of transforming growth factor beta1 signaling in resident interstitial cells attenuates profibrotic gene expression and preserves erythropoietin production during experimental kidney fibrosis in mice","volume":"100","author":"Fuchs","year":"2021","journal-title":"Kidney Int."},{"key":"10.1016\/j.bcp.2026.118401_b0045","doi-asserted-by":"crossref","first-page":"4641","DOI":"10.1039\/D2FO00204C","article-title":"Rosmarinic acid ameliorates renal interstitial fibrosis by inhibiting the phosphorylated-AKT mediated epithelial-mesenchymal transition in vitro and in vivo","volume":"13","author":"Hsieh","year":"2022","journal-title":"Food Funct."},{"key":"10.1016\/j.bcp.2026.118401_b0050","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1038\/s41586-020-2938-9","article-title":"Fibrosis: from mechanisms to medicines","volume":"587","author":"Henderson","year":"2020","journal-title":"Nature"},{"key":"10.1016\/j.bcp.2026.118401_b0055","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.tem.2023.09.001","article-title":"Mechanisms of kidney fibrosis and routes towards therapy","volume":"35","author":"Yamashita","year":"2024","journal-title":"Trends Endocrinol Metab"},{"key":"10.1016\/j.bcp.2026.118401_b0060","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1146\/annurev-physiol-022516-034227","article-title":"Mechanisms of renal fibrosis","volume":"80","author":"Humphreys","year":"2018","journal-title":"Annu. Rev. Physiol."},{"key":"10.1016\/j.bcp.2026.118401_b0065","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1038\/nrneph.2016.48","article-title":"TGF-\u03b2: the master regulator of fibrosis","volume":"12","author":"Meng","year":"2016","journal-title":"Nat. Rev. Nephrol."},{"key":"10.1016\/j.bcp.2026.118401_b0070","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.cyto.2017.10.015","article-title":"Role of interleukin 17 in TGF-beta signaling-mediated renal interstitial fibrosis","volume":"106","author":"Sun","year":"2018","journal-title":"Cytokine"},{"key":"10.1016\/j.bcp.2026.118401_b0075","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.ncrna.2017.04.001","article-title":"TGF-beta1 signaling in kidney disease: from Smads to long non-coding RNAs","volume":"2","author":"Tang","year":"2017","journal-title":"Noncoding RNA Res"},{"key":"10.1016\/j.bcp.2026.118401_b0080","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1038\/s41580-024-00716-0","article-title":"Fibroblast and myofibroblast activation in normal tissue repair and fibrosis","volume":"25","author":"Younesi","year":"2024","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.bcp.2026.118401_b0085","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1126\/science.285.5430.1028","article-title":"Integrin signaling","volume":"285","author":"Giancotti","year":"1999","journal-title":"Science"},{"key":"10.1016\/j.bcp.2026.118401_b0090","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1038\/s41573-021-00284-4","article-title":"Emerging therapeutic opportunities for integrin inhibitors","volume":"21","author":"Slack","year":"2022","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.bcp.2026.118401_b0095","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/S0092-8674(00)80545-0","article-title":"The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating pulmonary inflammation and fibrosis","volume":"96","author":"Munger","year":"1999","journal-title":"Cell"},{"key":"10.1016\/j.bcp.2026.118401_b0100","doi-asserted-by":"crossref","first-page":"6200","DOI":"10.1016\/j.cell.2024.08.036","article-title":"Dynamic allostery drives autocrine and paracrine TGF-\u03b2 signaling","volume":"187","author":"Jin","year":"2024","journal-title":"Cell"},{"key":"10.1016\/j.bcp.2026.118401_b0105","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1513\/pats.201201-003AW","article-title":"TGF-\u03b2 activation and lung fibrosis","volume":"9","author":"Tatler","year":"2012","journal-title":"Proc. Am. Thorac. Soc."},{"key":"10.1016\/j.bcp.2026.118401_b0110","doi-asserted-by":"crossref","first-page":"5487","DOI":"10.1021\/acs.jcim.0c00254","article-title":"Molecular simulation of \u03b1v\u03b26 Integrin Inhibitors","volume":"60","author":"Guest","year":"2020","journal-title":"J. Chem. Inf. Model."},{"key":"10.1016\/j.bcp.2026.118401_b0115","doi-asserted-by":"crossref","first-page":"e1316","DOI":"10.1002\/ctm2.1316","article-title":"Runx2 activates hepatic stellate cells to promote liver fibrosis via transcriptionally regulating Itgav expression","volume":"13","author":"Zhong","year":"2023","journal-title":"Clin. Transl. Med."},{"key":"10.1016\/j.bcp.2026.118401_b0120","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1016\/j.addr.2010.11.001","article-title":"Focal adhesion kinase and its signaling pathways in cell migration and angiogenesis","volume":"63","author":"Zhao","year":"2011","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.bcp.2026.118401_b0125","doi-asserted-by":"crossref","DOI":"10.4028\/b-XDTcg5","article-title":"Targeting Itga8 mitigates neurogenic bladder fibrosis driven by trem2(+) macrophage-derived Fn1 via FAK\/RhoA\/ROCK Signaling","author":"Wang","year":"2025","journal-title":"Adv. Sci. (weinh)"},{"key":"10.1016\/j.bcp.2026.118401_b0130","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2022.109409","article-title":"Nintedanib alleviates pulmonary fibrosis in vitro and in vivo by inhibiting the FAK\/ERK\/S100A4 signalling pathway","volume":"113","author":"Yang","year":"2022","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.bcp.2026.118401_b0135","doi-asserted-by":"crossref","first-page":"1546","DOI":"10.1681\/ASN.2021101343","article-title":"Complementary Nck1\/2 signaling in podocytes controls \u03b1 actinin-4-mediated actin organization, adhesion, and basement membrane composition","volume":"33","author":"Martin","year":"2022","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.bcp.2026.118401_b0140","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1016\/j.kint.2025.07.025","article-title":"Angiopoietin-like 4 exacerbates renal tubular epithelial cell pyroptosis in acute kidney injury via integrin beta5\/FAK signaling pathway","volume":"108","author":"Shen","year":"2025","journal-title":"Kidney Int."},{"key":"10.1016\/j.bcp.2026.118401_b0145","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1038\/s41580-024-00777-1","article-title":"The role and regulation of integrins in cell migration and invasion","volume":"26","author":"Chastney","year":"2025","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.bcp.2026.118401_b0150","doi-asserted-by":"crossref","first-page":"2449","DOI":"10.1016\/j.jid.2025.03.006","article-title":"Integrin alpha11beta1 as a key collagen receptor in human skin dermis: insight into fibroblast function and skin dermal aging","volume":"145","author":"Quan","year":"2025","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.bcp.2026.118401_b0155","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1186\/s13287-025-04559-0","article-title":"MicroRNA-4516 in extracellular vesicles-derived mesenchymal stem cells suppressed integrin alphaV-mediated lung fibrosis","volume":"16","author":"Sumiyoshi","year":"2025","journal-title":"Stem Cell Res Ther"},{"key":"10.1016\/j.bcp.2026.118401_b0160","doi-asserted-by":"crossref","first-page":"F159","DOI":"10.1152\/ajprenal.00546.2013","article-title":"RhoA\/Rho kinase mediates TGF-\u03b21-induced kidney myofibroblast activation through Poldip2\/Nox4-derived reactive oxygen species","volume":"307","author":"Manickam","year":"2014","journal-title":"Am. J. Physiol. Renal Physiol."},{"key":"10.1016\/j.bcp.2026.118401_b0165","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.kint.2025.08.030","article-title":"Critical role of transcription factor SOX4 in tubular epithelial cell dedifferentiation and fibroblast activation during kidney fibrosis","volume":"109","author":"Du","year":"2026","journal-title":"Kidney Int."},{"key":"10.1016\/j.bcp.2026.118401_b0170","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1038\/s41581-022-00590-z","article-title":"The fibrogenic niche in kidney fibrosis: components and mechanisms","volume":"18","author":"Li","year":"2022","journal-title":"Nat. Rev. Nephrol."},{"key":"10.1016\/j.bcp.2026.118401_b0175","doi-asserted-by":"crossref","first-page":"1474","DOI":"10.1136\/ard-2023-224129","article-title":"Ablation of integrin-mediated cell-collagen communication alleviates fibrosis","volume":"82","author":"Sawant","year":"2023","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.bcp.2026.118401_b0180","doi-asserted-by":"crossref","DOI":"10.1016\/j.bcp.2024.116255","article-title":"Mechanotransduction and the extracellular matrix: key drivers of lung pathologies and drug responsiveness","volume":"228","author":"Burgess","year":"2024","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.bcp.2026.118401_b0185","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1083\/jcb.200312172","article-title":"Integrin alphaVbeta6-mediated activation of latent TGF-beta requires the latent TGF-beta binding protein-1","volume":"165","author":"Annes","year":"2004","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.bcp.2026.118401_b0190","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1038\/s41419-024-06785-5","article-title":"Knockout of integrin alphavbeta6 protects against renal inflammation in chronic kidney disease by reduction of pro-inflammatory macrophages","volume":"15","author":"Zhu","year":"2024","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.bcp.2026.118401_b0195","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2025.147121","article-title":"Activation of transforming growth factor beta 1 through integrin alpha V beta 6 and its molecular insights into cancer progression, and future directions","volume":"324","author":"Deb","year":"2025","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.bcp.2026.118401_b0200","doi-asserted-by":"crossref","first-page":"e1546","DOI":"10.1002\/ctm2.1546","article-title":"Inhibition of TGFbeta1 activation prevents radiation-induced lung fibrosis","volume":"14","author":"Yi","year":"2024","journal-title":"Clin. Transl. Med."},{"key":"10.1016\/j.bcp.2026.118401_b0205","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1038\/s41581-024-00902-5","article-title":"Collagen formation, function and role in kidney disease","volume":"21","author":"De Gregorio","year":"2025","journal-title":"Nat. Rev. Nephrol."},{"key":"10.1016\/j.bcp.2026.118401_b0210","doi-asserted-by":"crossref","DOI":"10.1002\/pmic.202400354","article-title":"Association of Urinary Collagen Type III Degradation Product with Kidney Function and Fibrosis in Chronic Kidney Disease patients","volume":"25","author":"Martin","year":"2025","journal-title":"Proteomics"},{"key":"10.1016\/j.bcp.2026.118401_b0215","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1242\/jcs.188672","article-title":"The integrin-collagen connection\u2013a glue for tissue repair?","volume":"129","author":"Zeltz","year":"2016","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.bcp.2026.118401_b0220","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41392-022-01259-6","article-title":"Targeting integrin pathways: mechanisms and advances in therapy","volume":"8","author":"Pang","year":"2023","journal-title":"Signal Transduct. Target. Ther."},{"key":"10.1016\/j.bcp.2026.118401_b0225","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1083\/jcb.200107107","article-title":"Marching at the front and dragging behind: differential alphaVbeta3-integrin turnover regulates focal adhesion behavior","volume":"155","author":"Ballestrem","year":"2001","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.bcp.2026.118401_b0230","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1083\/jcb.201609037","article-title":"Integrin-mediated mechanotransduction","volume":"215","author":"Sun","year":"2016","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.bcp.2026.118401_b0235","article-title":"Effects of graphene quantum dots on renal fibrosis through alleviating oxidative stress and restoring mitochondrial membrane potential","volume":"12","author":"Kim","year":"2025","journal-title":"Adv. Sci. (Weinh)"},{"key":"10.1016\/j.bcp.2026.118401_b0240","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1186\/s12964-024-01603-z","article-title":"The c-Abl-RACK1-FAK signaling axis promotes renal fibrosis in mice through regulating fibroblast-myofibroblast transition","volume":"22","author":"Bao","year":"2024","journal-title":"Cell Commun. Signal"},{"key":"10.1016\/j.bcp.2026.118401_b0245","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1186\/s40164-023-00446-7","article-title":"Focal adhesion kinase: from biological functions to therapeutic strategies","volume":"12","author":"Tan","year":"2023","journal-title":"Exp. Hematol. Oncol."},{"key":"10.1016\/j.bcp.2026.118401_b0250","doi-asserted-by":"crossref","DOI":"10.1016\/j.bcp.2024.116246","article-title":"Targeting focal adhesion kinase (FAK) for cancer therapy: FAK inhibitors, FAK-based dual-target inhibitors and PROTAC degraders","volume":"224","author":"Yang","year":"2024","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.bcp.2026.118401_b0255","doi-asserted-by":"crossref","DOI":"10.1002\/smll.202505685","article-title":"Cellular responses to nanoscale topography mediated through the RhoA\/ROCK Pathway","volume":"21","author":"Schaumann","year":"2025","journal-title":"Small"},{"key":"10.1016\/j.bcp.2026.118401_b0260","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1016\/j.cels.2022.05.005","article-title":"A molecular clock controls periodically driven cell migration in confined spaces","volume":"13","author":"Lee","year":"2022","journal-title":"Cell Syst."},{"key":"10.1016\/j.bcp.2026.118401_b0265","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1186\/s12929-021-00730-w","article-title":"RhoA: a dubious molecule in cardiac pathophysiology","volume":"28","author":"Kilian","year":"2021","journal-title":"J. Biomed. Sci."},{"key":"10.1016\/j.bcp.2026.118401_b0270","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.154098","article-title":"Ligand-independent integrin beta1 signaling supports lung adenocarcinoma development","volume":"7","author":"Haake","year":"2022","journal-title":"JCI Insight"},{"key":"10.1016\/j.bcp.2026.118401_b0275","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1186\/s11658-025-00787-7","article-title":"The emerging role of human transmembrane RGD-based counter-receptors of integrins in health and disease","volume":"30","author":"Cabanas","year":"2025","journal-title":"Cell. Mol. Biol. Lett."},{"key":"10.1016\/j.bcp.2026.118401_b0280","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1038\/s41580-022-00531-5","article-title":"Organization, dynamics and mechanoregulation of integrin-mediated cell-ECM adhesions","volume":"24","author":"Kanchanawong","year":"2023","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.bcp.2026.118401_b0285","doi-asserted-by":"crossref","DOI":"10.3390\/cells14040266","article-title":"Mechanosignaling via integrins: pivotal players in liver fibrosis progression and therapy","volume":"14","author":"Sharip","year":"2025","journal-title":"Cells"}],"container-title":["Biochemical Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006295226007409?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006295226007409?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T11:00:14Z","timestamp":1788346814000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006295226007409"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,12]]},"references-count":57,"alternative-id":["S0006295226007409"],"URL":"https:\/\/doi.org\/10.1016\/j.bcp.2026.118401","relation":{},"ISSN":["0006-2952"],"issn-type":[{"value":"0006-2952","type":"print"}],"subject":[],"published":{"date-parts":[[2026,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Integrin \u03b1V\u03b23-mediated focal adhesion signaling promotes fibroblast activation during renal fibrosis","name":"articletitle","label":"Article Title"},{"value":"Biochemical Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bcp.2026.118401","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"118401"}}