{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T20:08:03Z","timestamp":1788898083492,"version":"build-2803163510"},"reference-count":65,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2020YFA0803900"],"award-info":[{"award-number":["2020YFA0803900"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012165","name":"Key Technologies Research and Development Program","doi-asserted-by":"publisher","award":["2024ZD0528604"],"award-info":[{"award-number":["2024ZD0528604"]}],"id":[{"id":"10.13039\/501100012165","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82073834"],"award-info":[{"award-number":["82073834"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82373858"],"award-info":[{"award-number":["82373858"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical Pharmacology"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1016\/j.bcp.2026.118413","type":"journal-article","created":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T15:11:01Z","timestamp":1788016261000},"page":"118413","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"P1","title":["Disruption of gut bacteria-derived hydrogen sulfide signaling mediates antibacterial-induced acute anorexia"],"prefix":"10.1016","volume":"254","author":[{"given":"Han","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-6085-9267","authenticated-orcid":false,"given":"Ling-Li","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hua-Jie","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-8955-1389","authenticated-orcid":false,"given":"Pei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian-Guo","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong-Sheng","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5042-3381","authenticated-orcid":false,"given":"Peng-Fei","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.bcp.2026.118413_b0005","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1038\/s42255-025-01301-1","article-title":"A food-sensitive olfactory circuit drives anticipatory satiety","volume":"7","author":"Bulk","year":"2025","journal-title":"Nat Metab"},{"key":"10.1016\/j.bcp.2026.118413_b0010","doi-asserted-by":"crossref","DOI":"10.1016\/j.appet.2025.107936","article-title":"Bidirectional associations between affect and food craving within and between individuals: a mega-analysis","volume":"209","author":"Aulbach","year":"2025","journal-title":"Appetite"},{"issue":"6741","key":"10.1016\/j.bcp.2026.118413_b0015","doi-asserted-by":"crossref","DOI":"10.1126\/science.adt0773","article-title":"Hedonic eating is controlled by dopamine neurons that oppose GLP-1R satiety","volume":"387","author":"Zhu","year":"2025","journal-title":"Science"},{"issue":"7","key":"10.1016\/j.bcp.2026.118413_b0020","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1038\/s41574-019-0210-x","article-title":"The circadian regulation of food intake","volume":"15","author":"Challet","year":"2019","journal-title":"Nat. Rev. Endocrinol."},{"issue":"6","key":"10.1016\/j.bcp.2026.118413_b0025","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.1016\/j.cgh.2021.07.004","article-title":"Food avoidance and restriction in irritable bowel syndrome: relevance for symptoms, quality of life and nutrient intake","volume":"20","author":"Melchior","year":"2022","journal-title":"Clin. Gastroenterol. Hepatol."},{"key":"10.1016\/j.bcp.2026.118413_b0030","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.11190","article-title":"Hippocampus ghrelin signaling mediates appetite through lateral hypothalamic orexin pathways","volume":"4","author":"Hsu","year":"2015","journal-title":"Elife"},{"issue":"5","key":"10.1016\/j.bcp.2026.118413_b0035","doi-asserted-by":"crossref","first-page":"727","DOI":"10.3945\/jn.116.240481","article-title":"Microbiota-gut-brain axis: modulator of host metabolism and appetite","volume":"147","author":"van de Wouw","year":"2017","journal-title":"J. Nutr."},{"issue":"10","key":"10.1016\/j.bcp.2026.118413_b0040","doi-asserted-by":"crossref","DOI":"10.1172\/JCI143772","article-title":"Roles for the gut microbiota in regulating neuronal feeding circuits","volume":"131","author":"Yu","year":"2021","journal-title":"J. Clin. Invest."},{"issue":"6086","key":"10.1016\/j.bcp.2026.118413_b0045","doi-asserted-by":"crossref","first-page":"1262","DOI":"10.1126\/science.1223813","article-title":"Host-gut microbiota metabolic interactions","volume":"336","author":"Nicholson","year":"2012","journal-title":"Science"},{"issue":"7610","key":"10.1016\/j.bcp.2026.118413_b0050","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1038\/nature18846","article-title":"Diet-microbiota interactions as moderators of human metabolism","volume":"535","author":"Sonnenburg","year":"2016","journal-title":"Nature"},{"issue":"6150","key":"10.1016\/j.bcp.2026.118413_b0055","doi-asserted-by":"crossref","DOI":"10.1126\/science.1241214","article-title":"Gut microbiota from twins discordant for obesity modulate metabolism in mice","volume":"341","author":"Ridaura","year":"2013","journal-title":"Science"},{"issue":"7122","key":"10.1016\/j.bcp.2026.118413_b0060","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1038\/nature05414","article-title":"An obesity-associated gut microbiome with increased capacity for energy harvest","volume":"444","author":"Turnbaugh","year":"2006","journal-title":"Nature"},{"issue":"8081","key":"10.1016\/j.bcp.2026.118413_b0065","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1038\/s41586-025-09301-7","article-title":"A gut sense for a microbial pattern regulates feeding","volume":"645","author":"Liu","year":"2025","journal-title":"Nature"},{"issue":"1","key":"10.1016\/j.bcp.2026.118413_b0070","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1152\/physrev.00028.2021","article-title":"Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs","volume":"103","author":"Cirino","year":"2023","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.bcp.2026.118413_b0075","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.bcp.2017.11.019","article-title":"Gasotransmitter hydrogen sulfide signaling in neuronal health and disease","volume":"149","author":"Paul","year":"2018","journal-title":"Biochem. Pharmacol."},{"issue":"5","key":"10.1016\/j.bcp.2026.118413_b0080","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1111\/cns.12228","article-title":"Aggravation of seizure-like events by hydrogen sulfide: involvement of multiple targets that control neuronal excitability","volume":"20","author":"Luo","year":"2014","journal-title":"CNS Neurosci. Ther."},{"issue":"9","key":"10.1016\/j.bcp.2026.118413_b0085","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1111\/cns.12585","article-title":"Hydrogen sulfide promotes surface insertion of hippocampal AMPA receptor GluR1 subunit via phosphorylating at serine-831\/serine-845 sites through a sulfhydration-dependent mechanism","volume":"22","author":"Li","year":"2016","journal-title":"CNS Neurosci. Ther."},{"issue":"7","key":"10.1016\/j.bcp.2026.118413_b0090","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1089\/ars.2016.6936","article-title":"Activity-dependent sulfhydration signal controls N-methyl-D-aspartate subtype glutamate receptor-dependent synaptic plasticity via increasing D-serine availability","volume":"27","author":"Li","year":"2017","journal-title":"Antioxid. Redox Signal."},{"issue":"1","key":"10.1016\/j.bcp.2026.118413_b0095","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1111\/jnc.12961","article-title":"Regulation of emotional memory by hydrogen sulfide: role of GluN2B-containing NMDA receptor in the amygdala","volume":"132","author":"Wang","year":"2015","journal-title":"J. Neurochem."},{"issue":"16","key":"10.1016\/j.bcp.2026.118413_b0100","doi-asserted-by":"crossref","first-page":"1880","DOI":"10.1089\/ars.2018.7503","article-title":"Reactive sulfur species emerge as gliotransmitters to support memory via sulfuration-dependent gating of NR2A-containing N-methyl-D-aspartate subtype glutamate receptor function","volume":"30","author":"Luo","year":"2019","journal-title":"Antioxid. Redox Signal."},{"issue":"8","key":"10.1016\/j.bcp.2026.118413_b0105","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1089\/ars.2016.6737","article-title":"Rapid antidepressant effect of hydrogen sulfide: evidence for activation of mTORC1-TrkB-AMPA receptor pathways","volume":"27","author":"Hou","year":"2017","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.bcp.2026.118413_b0110","doi-asserted-by":"crossref","first-page":"966","DOI":"10.3389\/fphar.2018.00966","article-title":"GYY4137 promotes mice feeding behavior via arcuate nucleus sulfur-sulfhydrylation and AMPK activation","volume":"9","author":"Zhou","year":"2018","journal-title":"Front. Pharmacol."},{"issue":"2","key":"10.1016\/j.bcp.2026.118413_b0115","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1152\/physrev.00017.2011","article-title":"Physiological implications of hydrogen sulfide: a whiff exploration that blossomed","volume":"92","author":"Wang","year":"2012","journal-title":"Physiol. Rev."},{"issue":"22","key":"10.1016\/j.bcp.2026.118413_b0120","doi-asserted-by":"crossref","first-page":"5031","DOI":"10.1111\/bph.15246","article-title":"Hydrogen sulfide signalling in the CNS - comparison with NO","volume":"177","author":"Kimura","year":"2020","journal-title":"Br. J. Pharmacol."},{"issue":"10","key":"10.1016\/j.bcp.2026.118413_b0125","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2022.110479","article-title":"Gut microbiota reinforce host antioxidant capacity via the generation of reactive sulfur species","volume":"38","author":"Uchiyama","year":"2022","journal-title":"Cell Rep."},{"issue":"6","key":"10.1016\/j.bcp.2026.118413_b0130","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1139\/m79-104","article-title":"Thiosulfate formation and associated isotope effects during sulfite reduction by Clostridium pasteurianum","volume":"25","author":"Chambers","year":"1979","journal-title":"Can. J. Microbiol."},{"issue":"6","key":"10.1016\/j.bcp.2026.118413_b0135","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1139\/m78-120","article-title":"Stable isotope fractionation by Clostridium pasteurianum. 2. Regulation of sulfite reductases by sulfur amino acids and their influence on sulfur isotope fractionation during SO32- and SO42- reduction","volume":"24","author":"Laishley","year":"1978","journal-title":"Can. J. Microbiol."},{"issue":"2","key":"10.1016\/j.bcp.2026.118413_b0140","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1099\/00221287-16-2-330","article-title":"The availability of sulphur for Clostridium perfringens and an examination of hydrogen sulphide production","volume":"16","author":"Fuchs","year":"1957","journal-title":"J. Gen. Microbiol."},{"issue":"2","key":"10.1016\/j.bcp.2026.118413_b0145","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1111\/j.1574-6968.2009.01750.x","article-title":"Lactate has the potential to promote hydrogen sulphide formation in the human colon","volume":"299","author":"Marquet","year":"2009","journal-title":"FEMS Microbiol. Lett."},{"issue":"1","key":"10.1016\/j.bcp.2026.118413_b0150","doi-asserted-by":"crossref","DOI":"10.1080\/19490976.2024.2419565","article-title":"Regulatory mechanism of cysteine-dependent methionine biosynthesis in Bifidobacterium longum: insights into sulfur metabolism in gut microbiota","volume":"16","author":"Kim","year":"2024","journal-title":"Gut Microbes"},{"issue":"4","key":"10.1016\/j.bcp.2026.118413_b0155","doi-asserted-by":"crossref","DOI":"10.1093\/femsle\/fnx028","article-title":"Enrichment of sulfidogenic bacteria from the human intestinal tract","volume":"364","author":"Feng","year":"2017","journal-title":"FEMS Microbiol. Lett."},{"issue":"6058","key":"10.1016\/j.bcp.2026.118413_b0160","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1126\/science.1209855","article-title":"H2S: a universal defense against antibiotics in bacteria","volume":"334","author":"Shatalin","year":"2011","journal-title":"Science"},{"issue":"8","key":"10.1016\/j.bcp.2026.118413_b0165","doi-asserted-by":"crossref","first-page":"1601","DOI":"10.1038\/s42255-024-01068-x","article-title":"Hydrogen sulfide produced by the gut microbiota impairs host metabolism via reducing GLP-1 levels in male mice","volume":"6","author":"Qi","year":"2024","journal-title":"Nat Metab"},{"issue":"25","key":"10.1016\/j.bcp.2026.118413_b0170","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2503677122","article-title":"Gut sulfide metabolism modulates behavior and brain bioenergetics","volume":"122","author":"Kumar","year":"2025","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"1","key":"10.1016\/j.bcp.2026.118413_b0175","doi-asserted-by":"crossref","first-page":"1970","DOI":"10.1038\/s41467-021-22097-0","article-title":"Fasting alters the gut microbiome reducing blood pressure and body weight in metabolic syndrome patients","volume":"12","author":"Maifeld","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bcp.2026.118413_b0180","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2022.922727","article-title":"Intermittent fasting positively modulates human gut microbial diversity and ameliorates blood lipid profile","volume":"13","author":"Khan","year":"2022","journal-title":"Front. Microbiol."},{"issue":"5","key":"10.1016\/j.bcp.2026.118413_b0185","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.116.004971","article-title":"Endogenous hydrogen sulfide enhances carotid sinus baroreceptor sensitivity by activating the transient receptor potential cation channel subfamily V member 1 (TRPV1) channel","volume":"6","author":"Yu","year":"2017","journal-title":"J. Am. Heart Assoc."},{"key":"10.1016\/j.bcp.2026.118413_b0190","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2022.102233","article-title":"Overproduction of hydrogen sulfide, generated by cystathionine beta-synthase, disrupts brain wave patterns and contributes to neurobehavioral dysfunction in a rat model of down syndrome","volume":"51","author":"Panagaki","year":"2022","journal-title":"Redox Biol."},{"issue":"6","key":"10.1016\/j.bcp.2026.118413_b0195","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1124\/mol.113.086744","article-title":"Orexin-a activates hypothalamic AMP-activated protein kinase signaling through a Ca2+-dependent mechanism involving voltage-gated L-type calcium channel","volume":"84","author":"Wu","year":"2013","journal-title":"Mol. Pharmacol."},{"issue":"23","key":"10.1016\/j.bcp.2026.118413_b0200","doi-asserted-by":"crossref","first-page":"7944","DOI":"10.1128\/JB.186.23.7944-7950.2004","article-title":"Physiological and gene expression analysis of inhibition of Desulfovibrio vulgaris Hildenborough by nitrite","volume":"186","author":"Haveman","year":"2004","journal-title":"J. Bacteriol."},{"issue":"3","key":"10.1016\/j.bcp.2026.118413_b0205","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.biopsych.2018.09.024","article-title":"Gephyrin palmitoylation in basolateral amygdala mediates the anxiolytic action of benzodiazepine","volume":"85","author":"Shen","year":"2019","journal-title":"Biol. Psychiatry"},{"issue":"2","key":"10.1016\/j.bcp.2026.118413_b0210","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1111\/bph.14519","article-title":"Metformin produces anxiolytic-like effects in rats by facilitating GABA(A) receptor trafficking to membrane","volume":"176","author":"Fan","year":"2019","journal-title":"Br. J. Pharmacol."},{"issue":"17","key":"10.1016\/j.bcp.2026.118413_b0215","doi-asserted-by":"crossref","first-page":"4641","DOI":"10.1002\/anie.201300841","article-title":"Identification of cystathionine beta-synthase inhibitors using a hydrogen sulfide selective probe","volume":"52","author":"Thorson","year":"2013","journal-title":"Angew. Chem. Int. Ed. Engl."},{"issue":"3","key":"10.1016\/j.bcp.2026.118413_b0220","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1039\/C2AN36113B","article-title":"Fluorescent probe for highly selective and sensitive detection of hydrogen sulfide in living cells and cardiac tissues","volume":"138","author":"Chen","year":"2013","journal-title":"Analyst"},{"issue":"1","key":"10.1016\/j.bcp.2026.118413_b0225","doi-asserted-by":"crossref","first-page":"35","DOI":"10.3390\/nu17010035","article-title":"Effects of long-term fasting on gut microbiota, serum metabolome, and their association in male adults","volume":"17","author":"Wu","year":"2025","journal-title":"Nutrients"},{"issue":"9","key":"10.1016\/j.bcp.2026.118413_b0230","doi-asserted-by":"crossref","first-page":"4189","DOI":"10.1128\/AEM.65.9.4189-4196.1999","article-title":"On the occurrence of anoxic microniches, denitrification, and sulfate reduction in aerated activated sludge","volume":"65","author":"Schramm","year":"1999","journal-title":"Appl. Environ. Microbiol."},{"issue":"5","key":"10.1016\/j.bcp.2026.118413_b0235","doi-asserted-by":"crossref","first-page":"2166","DOI":"10.1128\/AEM.66.5.2166-2174.2000","article-title":"Molecular ecological analysis of the succession and diversity of sulfate-reducing bacteria in the mouse gastrointestinal tract","volume":"66","author":"Deplancke","year":"2000","journal-title":"Appl. Environ. Microbiol."},{"issue":"6","key":"10.1016\/j.bcp.2026.118413_b0240","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1089\/ars.2011.4507","article-title":"The neuroprotection of hydrogen sulfide against MPTP-induced dopaminergic neuron degeneration involves uncoupling protein 2 rather than ATP-sensitive potassium channels","volume":"17","author":"Lu","year":"2012","journal-title":"Antioxid. Redox Signal."},{"issue":"2","key":"10.1016\/j.bcp.2026.118413_b0245","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1111\/j.1474-9726.2009.00543.x","article-title":"Neuroprotective effects of hydrogen sulfide on Parkinson's disease rat models","volume":"9","author":"Hu","year":"2010","journal-title":"Aging Cell"},{"issue":"6","key":"10.1016\/j.bcp.2026.118413_b0250","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1038\/nrn3745","article-title":"Neurobiology of food intake in health and disease","volume":"15","author":"Morton","year":"2014","journal-title":"Nat. Rev. Neurosci."},{"issue":"6982","key":"10.1016\/j.bcp.2026.118413_b0255","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1038\/nature02440","article-title":"AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus","volume":"428","author":"Minokoshi","year":"2004","journal-title":"Nature"},{"issue":"6","key":"10.1016\/j.bcp.2026.118413_b0260","doi-asserted-by":"crossref","first-page":"896","DOI":"10.3390\/biom11060896","article-title":"Hydrogen sulfide H2S and polysulfide H2Sn signaling: the first 25 years","volume":"11","author":"Kimura","year":"2021","journal-title":"Biomolecules"},{"issue":"68","key":"10.1016\/j.bcp.2026.118413_b0265","doi-asserted-by":"crossref","first-page":"re2","DOI":"10.1126\/scisignal.268re2","article-title":"Signaling by gasotransmitters","volume":"2","author":"Mustafa","year":"2009","journal-title":"Sci. Signal."},{"issue":"15","key":"10.1016\/j.bcp.2026.118413_b0270","doi-asserted-by":"crossref","first-page":"1906","DOI":"10.1089\/ars.2012.4645","article-title":"Hydrogen sulfide protects against cellular senescence via S-sulfhydration of Keap1 and activation of Nrf2","volume":"18","author":"Yang","year":"2013","journal-title":"Antioxid. Redox Signal."},{"issue":"3","key":"10.1016\/j.bcp.2026.118413_b0275","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.anaerobe.2010.02.002","article-title":"First isolation of Desulfovibrio from the human vaginal flora","volume":"16","author":"Ichiishi","year":"2010","journal-title":"Anaerobe"},{"issue":"2","key":"10.1016\/j.bcp.2026.118413_b0280","doi-asserted-by":"crossref","first-page":"233","DOI":"10.3201\/eid3202.251581","article-title":"Desulfovibrio bacteremia in patients with abdominal infections, Japan, 2020-2025","volume":"32","author":"Watanabe","year":"2026","journal-title":"Emerg. Infect. Dis."},{"issue":"12","key":"10.1016\/j.bcp.2026.118413_b0285","doi-asserted-by":"crossref","first-page":"5308","DOI":"10.1128\/AAC.00630-09","article-title":"Susceptibilities of 23 Desulfovibrio isolates from humans","volume":"53","author":"Nakao","year":"2009","journal-title":"Antimicrob. Agents Chemother."},{"issue":"6","key":"10.1016\/j.bcp.2026.118413_b0290","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1016\/j.cmet.2014.11.008","article-title":"Diet and feeding pattern affect the diurnal dynamics of the gut microbiome","volume":"20","author":"Zarrinpar","year":"2014","journal-title":"Cell Metab."},{"issue":"1","key":"10.1016\/j.bcp.2026.118413_b0295","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.chom.2014.11.010","article-title":"Diet dominates host genotype in shaping the murine gut microbiota","volume":"17","author":"Carmody","year":"2015","journal-title":"Cell Host Microbe"},{"issue":"1","key":"10.1016\/j.bcp.2026.118413_b0300","doi-asserted-by":"crossref","first-page":"2222","DOI":"10.1038\/s41467-025-57574-3","article-title":"Microbiota-derived H2S induces c-kit+ cDC1 autophagic cell death and liver inflammation in metabolic dysfunction-associated steatohepatitis","volume":"16","author":"Song","year":"2025","journal-title":"Nat. Commun."},{"issue":"11","key":"10.1016\/j.bcp.2026.118413_b0305","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/j.tibs.2015.08.007","article-title":"H2S: a novel gasotransmitter that signals by sulfhydration","volume":"40","author":"Paul","year":"2015","journal-title":"Trends Biochem. Sci"},{"issue":"2","key":"10.1016\/j.bcp.2026.118413_b0310","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.mce.2012.06.012","article-title":"AMPK and the neuroendocrine regulation of appetite and energy expenditure","volume":"366","author":"Stark","year":"2013","journal-title":"Mol. Cell. Endocrinol."},{"issue":"7206","key":"10.1016\/j.bcp.2026.118413_b0315","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1038\/nature07181","article-title":"UCP2 mediates ghrelin's action on NPY\/AgRP neurons by lowering free radicals","volume":"454","author":"Andrews","year":"2008","journal-title":"Nature"},{"issue":"5","key":"10.1016\/j.bcp.2026.118413_b0320","first-page":"679","article-title":"Metronidazole","volume":"54","author":"Freeman","year":"1997","journal-title":"A Therapeutic Review and Update, Drugs"},{"key":"10.1016\/j.bcp.2026.118413_b0325","first-page":"60","article-title":"Pharmacokinetics of nitroimidazoles","volume":"26","author":"Andersson","year":"1981","journal-title":"Spectrum of Adverse Reactions, Scand J Infect Dis Suppl"}],"container-title":["Biochemical Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006295226007525?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006295226007525?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T19:49:25Z","timestamp":1788896965000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006295226007525"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,12]]},"references-count":65,"alternative-id":["S0006295226007525"],"URL":"https:\/\/doi.org\/10.1016\/j.bcp.2026.118413","relation":{},"ISSN":["0006-2952"],"issn-type":[{"value":"0006-2952","type":"print"}],"subject":[],"published":{"date-parts":[[2026,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Disruption of gut bacteria-derived hydrogen sulfide signaling mediates antibacterial-induced acute anorexia","name":"articletitle","label":"Article Title"},{"value":"Biochemical Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bcp.2026.118413","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"118413"}}