{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T17:06:04Z","timestamp":1790355964931,"version":"4.1.0"},"reference-count":52,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82001642"],"award-info":[{"award-number":["82001642"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003819","name":"Natural Science Foundation of Hubei Province","doi-asserted-by":"publisher","award":["2020CFB228"],"award-info":[{"award-number":["2020CFB228"]}],"id":[{"id":"10.13039\/501100003819","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical Pharmacology"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1016\/j.bcp.2026.118493","type":"journal-article","created":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T00:07:12Z","timestamp":1790035632000},"page":"118493","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"P2","title":["Metabolic reprogramming of decidual macrophages impairs maternal\u2013fetal interface homeostasis and contributes to recurrent spontaneous abortion"],"prefix":"10.1016","volume":"254","author":[{"given":"Shujuan","family":"Wu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huifan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liangfei","family":"Ao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gengxiang","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhuoni","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4943-1859","authenticated-orcid":false,"given":"Hong","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7378-8140","authenticated-orcid":false,"given":"Jiao","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.bcp.2026.118493_b0005","doi-asserted-by":"crossref","DOI":"10.1111\/aji.13052","article-title":"Genome-wide identification of microRNAs in decidual natural killer cells from patients with unexplained recurrent spontaneous abortion","volume":"80","author":"Li","year":"2018","journal-title":"Am. J. Reprod. Immunol."},{"issue":"21","key":"10.1016\/j.bcp.2026.118493_b0010","doi-asserted-by":"crossref","DOI":"10.3390\/ijms20215332","article-title":"Endometrial immune dysfunction in recurrent pregnancy loss","volume":"20","author":"Ticconi","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.bcp.2026.118493_b0015","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.jri.2017.10.045","article-title":"The role of decidual immune cells on human pregnancy","volume":"124","author":"Liu","year":"2017","journal-title":"J. Reprod. Immunol."},{"key":"10.1016\/j.bcp.2026.118493_b0020","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.994888","article-title":"Decidual macrophages in recurrent spontaneous abortion","volume":"13","author":"Zhao","year":"2022","journal-title":"Front. Immunol."},{"issue":"Pt A","key":"10.1016\/j.bcp.2026.118493_b0025","article-title":"CTRP6 regulates M1 macrophage polarization via the PPAR-\u03b3\/NF-\u03baB pathway and reprogramming glycolysis in recurrent spontaneous abortion","volume":"124","author":"Yan","year":"2023","journal-title":"Int. Immunopharmacol."},{"issue":"1","key":"10.1016\/j.bcp.2026.118493_b0030","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1186\/s13045-023-01478-6","article-title":"Metabolism, metabolites, and macrophages in cancer","volume":"16","author":"Li","year":"2023","journal-title":"J. Hematol. Oncol."},{"issue":"14","key":"10.1016\/j.bcp.2026.118493_b0035","article-title":"Inflammatory fibroblast-like synoviocyte-derived exosomes aggravate osteoarthritis via enhancing macrophage glycolysis","volume":"11","author":"Liu","year":"2024","journal-title":"Adv. Sci. (Weinh)."},{"issue":"6","key":"10.1016\/j.bcp.2026.118493_b0040","doi-asserted-by":"crossref","DOI":"10.1136\/jitc-2021-002548","article-title":"S100A4 enhances protumor macrophage polarization by control of PPAR-\u03b3-dependent induction of fatty acid oxidation","volume":"9","author":"Liu","year":"2021","journal-title":"J. Immunother. Cancer"},{"issue":"5","key":"10.1016\/j.bcp.2026.118493_b0045","doi-asserted-by":"crossref","DOI":"10.1002\/ctm2.70340","article-title":"VSIG4 promotes tumour-associated macrophage M2 polarization and immune escape in colorectal cancer via fatty acid oxidation pathway","volume":"15","author":"Liu","year":"2025","journal-title":"Clin. Transl. Med."},{"issue":"17","key":"10.1016\/j.bcp.2026.118493_b0050","doi-asserted-by":"crossref","first-page":"7216","DOI":"10.7150\/thno.78467","article-title":"Decorin promotes decidual M1-like macrophage polarization via mitochondrial dysfunction resulting in recurrent pregnancy loss","volume":"12","author":"Wang","year":"2022","journal-title":"Theranostics."},{"issue":"1","key":"10.1016\/j.bcp.2026.118493_b0055","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1186\/s12951-025-03260-x","article-title":"Astragaloside IV- loaded biomimetic nanoparticles target I\u03baB\u03b1 to regulate neutrophil extracellular trap formation for sepsis therapy","volume":"23","author":"Wu","year":"2025","journal-title":"J Nanobiotechnology."},{"issue":"6","key":"10.1016\/j.bcp.2026.118493_b0060","first-page":"2376","article-title":"FasL on decidual macrophages mediates trophoblast apoptosis: A potential cause of recurrent miscarriage","volume":"43","author":"Ding","year":"2019","journal-title":"Int. J. Mol. Med."},{"issue":"1","key":"10.1016\/j.bcp.2026.118493_b0065","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1093\/humrep\/dey347","article-title":"The role of the PD-1\/PD-L1 axis in macrophage differentiation and function during pregnancy","volume":"34","author":"Zhang","year":"2019","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.bcp.2026.118493_b0070","doi-asserted-by":"crossref","DOI":"10.1016\/j.jri.2022.103647","article-title":"The miR-410-5p \/ITGA6 axis participates in the pathogenesis of recurrent abortion by regulating the biological function of trophoblast","volume":"152","author":"Wu","year":"2022","journal-title":"J. Reprod. Immunol."},{"issue":"1","key":"10.1016\/j.bcp.2026.118493_b0075","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1186\/s12964-020-00579-w","article-title":"Autophagy suppression of trophoblast cells induces pregnancy loss by activating decidual NK cytotoxicity and inhibiting trophoblast invasion","volume":"18","author":"Tan","year":"2020","journal-title":"Cell Commun. Signal"},{"issue":"11","key":"10.1016\/j.bcp.2026.118493_b0080","doi-asserted-by":"crossref","DOI":"10.1111\/cpr.13125","article-title":"Single-cell transcriptome analysis reveals defective decidua stromal niche attributes to recurrent spontaneous abortion","volume":"54","author":"Du","year":"2021","journal-title":"Cell Prolif."},{"issue":"5","key":"10.1016\/j.bcp.2026.118493_b0085","doi-asserted-by":"crossref","DOI":"10.1111\/cpr.12802","article-title":"Placental endovascular extravillous trophoblasts (enEVTs) educate maternal T-cell differentiation along the maternal-placental circulation","volume":"53","author":"Ma","year":"2020","journal-title":"Cell Prolif."},{"issue":"3","key":"10.1016\/j.bcp.2026.118493_b0090","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1006236","article-title":"Alternate splicing of transcripts shape macrophage response to Mycobacterium tuberculosis infection","volume":"13","author":"Kalam","year":"2017","journal-title":"PLoS Pathog."},{"issue":"1","key":"10.1016\/j.bcp.2026.118493_b0095","doi-asserted-by":"crossref","first-page":"7991","DOI":"10.1038\/s41467-023-43599-z","article-title":"Structural insights into the role of GTPBP10 in the RNA maturation of the mitoribosome","volume":"14","author":"Nguyen","year":"2023","journal-title":"Nat. Commun."},{"issue":"16","key":"10.1016\/j.bcp.2026.118493_b0100","doi-asserted-by":"crossref","first-page":"8471","DOI":"10.1093\/nar\/gky701","article-title":"The human Obg protein GTPBP10 is involved in mitoribosomal biogenesis","volume":"46","author":"Lavdovskaia","year":"2018","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.bcp.2026.118493_b0105","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2022.109473","article-title":"Deletion of insulin-like growth factor II mRNA-binding protein 3 participates in the pathogenesis of recurrent spontaneous abortion by inhibiting IL-10 secretion and inducing M1 polarization","volume":"114","author":"Zhang","year":"2023","journal-title":"Int. Immunopharmacol."},{"issue":"10","key":"10.1016\/j.bcp.2026.118493_b0110","doi-asserted-by":"crossref","first-page":"2820","DOI":"10.1007\/s43032-021-00790-1","article-title":"Downregulation of EZH2 in trophoblasts induces decidual M1 macrophage polarization: a potential cause of recurrent spontaneous abortion","volume":"29","author":"Shang","year":"2022","journal-title":"Reprod. Sci."},{"issue":"11","key":"10.1016\/j.bcp.2026.118493_b0115","doi-asserted-by":"crossref","DOI":"10.1016\/j.immuni.2021.09.010","article-title":"IL-33-induced metabolic reprogramming controls the differentiation of alternatively activated macrophages and the resolution of inflammation","volume":"54","author":"Faas","year":"2021","journal-title":"Immunity"},{"issue":"9","key":"10.1016\/j.bcp.2026.118493_b0120","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1038\/ni.3796","article-title":"\u03b1-ketoglutarate orchestrates macrophage activation through metabolic and epigenetic reprogramming","volume":"18","author":"Liu","year":"2017","journal-title":"Nat. Immunol."},{"issue":"10","key":"10.1016\/j.bcp.2026.118493_b0125","doi-asserted-by":"crossref","first-page":"3699","DOI":"10.1172\/JCI84431","article-title":"HIF1\u03b1 and metabolic reprogramming in inflammation","volume":"126","author":"Corcoran","year":"2016","journal-title":"J. Clin. Invest."},{"issue":"4","key":"10.1016\/j.bcp.2026.118493_b0135","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1038\/s41419-020-2426-z","article-title":"MSC-induced lncRNA HCP5 drove fatty acid oxidation through miR-3619-5p\/AMPK\/PGC1\u03b1\/CEBPB axis to promote stemness and chemo-resistance of gastric cancer","volume":"11","author":"Wu","year":"2020","journal-title":"Cell Death Dis."},{"issue":"2","key":"10.1016\/j.bcp.2026.118493_b0140","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1158\/0008-5472.CAN-23-0184","article-title":"Metabolomic rewiring promotes endocrine therapy resistance in breast cancer","volume":"84","author":"Ahn","year":"2024","journal-title":"Cancer Res."},{"key":"10.1016\/j.bcp.2026.118493_b0145","doi-asserted-by":"crossref","DOI":"10.1016\/j.canlet.2024.217177","article-title":"6-Phosphogluconate dehydrogenase promotes glycolysis and fatty acid synthesis by inhibiting the AMPK pathway in lung adenocarcinoma cells","volume":"601","author":"Wu","year":"2024","journal-title":"Cancer Lett."},{"key":"10.1016\/j.bcp.2026.118493_b0150","article-title":"The mechanism of insulin-like growth factor II mRNA-binging protein 3 induce decidualization and maternal-fetal interface cross talk by TGF-\u03b21 in recurrent spontaneous abortion","volume":"10","author":"Zhu","year":"2022","journal-title":"Front. Cell Dev. Biol."},{"issue":"4","key":"10.1016\/j.bcp.2026.118493_b0155","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1007\/s00418-018-1699-0","article-title":"Human trophoblast invasion: new and unexpected routes and functions","volume":"150","author":"Moser","year":"2018","journal-title":"Histochem. Cell Biol."},{"issue":"1","key":"10.1016\/j.bcp.2026.118493_b0160","first-page":"65","article-title":"Comparing the frequency of CD4+T cells in recurrent spontaneous abortion women with and without anti-thyroid peroxidase (TPO)","volume":"19","author":"Basimi","year":"2020","journal-title":"Iran. J. Allergy Asthma Immunol."},{"key":"10.1016\/j.bcp.2026.118493_b0165","doi-asserted-by":"crossref","first-page":"2025","DOI":"10.3389\/fimmu.2020.02025","article-title":"T helper (Th) cell profiles in pregnancy and recurrent pregnancy losses: Th1\/Th2\/Th9\/Th17\/Th22\/Tfh cells","volume":"11","author":"Wang","year":"2020","journal-title":"Front. Immunol."},{"issue":"12","key":"10.1016\/j.bcp.2026.118493_b0170","doi-asserted-by":"crossref","first-page":"3303","DOI":"10.1007\/s43032-021-00599-y","article-title":"The role of immune cells in recurrent spontaneous abortion","volume":"28","author":"Li","year":"2021","journal-title":"Reprod. Sci."},{"issue":"1","key":"10.1016\/j.bcp.2026.118493_b0175","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1111\/imr.13080","article-title":"Monocytes and macrophages in pregnancy: the good, the bad, and the ugly","volume":"308","author":"True","year":"2022","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.bcp.2026.118493_b0180","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2022.108930","article-title":"miR-146a-5p enhances embryo survival in unexplained recurrent spontaneous abortion by promoting M2 polarization of decidual macrophages","volume":"110","author":"Ye","year":"2022","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.bcp.2026.118493_b0185","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2022.891748","article-title":"SEC5 is involved in M2 polarization of macrophages via the STAT6 pathway, and its dysfunction in decidual macrophages is associated with recurrent spontaneous abortion","volume":"10","author":"Yang","year":"2022","journal-title":"Front. Cell Dev. Biol."},{"key":"10.1016\/j.bcp.2026.118493_b0190","article-title":"Deletion of ACLY disrupts histone acetylation and IL-10 secretion in trophoblasts, which inhibits M2 polarization of macrophages: a possible role in recurrent spontaneous abortion","volume":"2022","author":"Chen","year":"2022","journal-title":"Oxid Med Cell Longev."},{"key":"10.1016\/j.bcp.2026.118493_b0195","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.canlet.2019.03.015","article-title":"Metabolic reprogramming of macrophages during infections and cancer","volume":"452","author":"Wang","year":"2019","journal-title":"Cancer Lett."},{"issue":"Pt B","key":"10.1016\/j.bcp.2026.118493_b0200","article-title":"LncRNA AOC4P recruits TRAF6 to regulate EZH2 ubiquitination and participates in trophoblast glycolysis and M2 macrophage polarization which is associated with recurrent spontaneous abortion","volume":"125","author":"Wu","year":"2023","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.bcp.2026.118493_b0205","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2024.156178","article-title":"Key role of PPAR-\u03b3-mediated suppression of the NF\u03baB signaling pathway in rutin's antidepressant effect","volume":"135","author":"Yin","year":"2024","journal-title":"Phytomedicine"},{"key":"10.1016\/j.bcp.2026.118493_b0210","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2025.115068","article-title":"Lovastatin alleviates DSS-induced colitis by modulating macrophage polarization via the PPAR\u03b3-NF-\u03baB pathway","volume":"161","author":"Zhu","year":"2025","journal-title":"Int. Immunopharmacol."},{"issue":"2","key":"10.1016\/j.bcp.2026.118493_b0215","doi-asserted-by":"crossref","first-page":"895","DOI":"10.7150\/ijbs.121947","article-title":"Excessive kynurenine metabolism impairs lysosomal acidification and triggers mtDNA release via the AHR\/CISH\/ATP6V1A axis in decidual macrophages associated with unexplained recurrent pregnancy loss","volume":"22","author":"Song","year":"2026","journal-title":"Int J Biol Sci."},{"issue":"5","key":"10.1016\/j.bcp.2026.118493_b0220","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1093\/biolre\/ioaf040","article-title":"Therapeutic targeting of the Tryptophan-Kynurenine Axis for HTR-8\/SVneo trophoblast proliferation and migration in unexplained recurrent spontaneous abortion\u2020","volume":"112","author":"Jin","year":"2025","journal-title":"Biol. Reprod."},{"issue":"1","key":"10.1016\/j.bcp.2026.118493_b0225","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1186\/s12967-023-04772-6","article-title":"The role of AMPK in macrophage metabolism, function and polarisation","volume":"21","author":"Cui","year":"2023","journal-title":"J. Transl. Med."},{"key":"10.1016\/j.bcp.2026.118493_b0230","doi-asserted-by":"crossref","DOI":"10.1016\/j.matdes.2024.113291","article-title":"Ginsenoside Rb1-loaded bionic nanoparticles alleviate sepsis-induced acute lung injury by reducing mitochondrial oxidative stress to inhibit macrophage PANoptosis","volume":"245","author":"Wu","year":"2024","journal-title":"Mater. Des."},{"issue":"4","key":"10.1016\/j.bcp.2026.118493_b0235","doi-asserted-by":"crossref","DOI":"10.3390\/cancers12040862","article-title":"Metabolic heterogeneity of cancer cells: an interplay between HIF-1, GLUTs, and AMPK","volume":"12","author":"Moldogazieva","year":"2020","journal-title":"Cancers (Basel)"},{"issue":"2","key":"10.1016\/j.bcp.2026.118493_b0240","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1007\/s00441-022-03579-z","article-title":"MAX deficiency impairs human endometrial decidualization through down-regulating OSR2 in women with recurrent spontaneous abortion","volume":"388","author":"Ma","year":"2022","journal-title":"Cell Tissue Res."},{"issue":"2","key":"10.1016\/j.bcp.2026.118493_b0245","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1093\/biolre\/ioad053","article-title":"Ubiquitin-specific protease 7 prevents recurrent spontaneous abortion by targeting enhancer of zeste homolog 2 to regulate trophoblast proliferation, apoptosis, migration, and invasion through the Wnt\/\u03b2-catenin pathway\u2020","volume":"109","author":"Zhou","year":"2023","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.bcp.2026.118493_b0250","article-title":"Crosstalk between trophoblasts and decidual immune cells: the cornerstone of maternal-fetal immunotolerance","volume":"12","author":"Xu","year":"2021","journal-title":"Front. Immunol."},{"issue":"4","key":"10.1016\/j.bcp.2026.118493_b0255","doi-asserted-by":"crossref","first-page":"2136","DOI":"10.1111\/jcmm.16191","article-title":"M2 macrophage-derived G-CSF promotes trophoblasts EMT, invasion and migration via activating PI3K\/Akt\/Erk1\/2 pathway to mediate normal pregnancy","volume":"25","author":"Ding","year":"2021","journal-title":"J. Cell Mol. Med."},{"issue":"7970","key":"10.1016\/j.bcp.2026.118493_b0260","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1038\/s41586-023-06298-9","article-title":"A spatially resolved timeline of the human maternal-fetal interface","volume":"619","author":"Greenbaum","year":"2023","journal-title":"Nature"},{"key":"10.1016\/j.bcp.2026.118493_b0265","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2024.1379537","article-title":"Decidual macrophages and Hofbauer cells in fetal growth restriction","volume":"15","author":"Bezemer","year":"2024","journal-title":"Front. Immunol."}],"container-title":["Biochemical Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000629522600835X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000629522600835X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T16:20:56Z","timestamp":1790353256000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S000629522600835X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,12]]},"references-count":52,"alternative-id":["S000629522600835X"],"URL":"https:\/\/doi.org\/10.1016\/j.bcp.2026.118493","relation":{},"ISSN":["0006-2952"],"issn-type":[{"value":"0006-2952","type":"print"}],"subject":[],"published":{"date-parts":[[2026,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Metabolic reprogramming of decidual macrophages impairs maternal\u2013fetal interface homeostasis and contributes to recurrent spontaneous abortion","name":"articletitle","label":"Article Title"},{"value":"Biochemical Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bcp.2026.118493","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"118493"}}