{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T16:58:45Z","timestamp":1791305925689,"version":"4.3.1"},"reference-count":59,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2013,2,1]],"date-time":"2013-02-01T00:00:00Z","timestamp":1359676800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,2,1]],"date-time":"2013-02-01T00:00:00Z","timestamp":1359676800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Best Practice & Research Clinical Endocrinology & Metabolism"],"published-print":{"date-parts":[[2013,2]]},"DOI":"10.1016\/j.beem.2012.11.003","type":"journal-article","created":{"date-parts":[[2012,12,22]],"date-time":"2012-12-22T02:02:34Z","timestamp":1356141754000},"page":"35-45","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":77,"title":["Hormonal contraceptives and arterial disease: An epidemiological update"],"prefix":"10.1016","volume":"27","author":[{"given":"Genevi\u00e8ve","family":"Plu-Bureau","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justine","family":"Hugon-Rodin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorraine","family":"Maitrot-Mantelet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marianne","family":"Canonico","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.beem.2012.11.003_bib1","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1093\/humupd\/5.6.721","article-title":"Cardiovascular disease and combined oral contraceptives: reviewing the evidence and balancing the risks","volume":"5","author":"Farley","year":"1999","journal-title":"Human Reproduction Update"},{"key":"10.1016\/j.beem.2012.11.003_bib2","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1016\/j.contraception.2011.02.013","article-title":"Current issues and available options in combined hormonal contraception","volume":"84","author":"Bitzer","year":"2011","journal-title":"Contraception"},{"key":"10.1016\/j.beem.2012.11.003_bib3","doi-asserted-by":"crossref","first-page":"3863","DOI":"10.1210\/jc.2004-1958","article-title":"Association between the current use of low-dose oral contraceptives and cardiovascular arterial disease: a meta-analysis","volume":"90","author":"Baillargeon","year":"2005","journal-title":"Journal of Clinical Endocrinology and Metabolism"},{"key":"10.1016\/j.beem.2012.11.003_bib4","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/S0010-7824(03)00073-8","article-title":"Oral contraceptives use and the risk of myocardial infarction: a meta-analysis","volume":"68","author":"Khader","year":"2003","journal-title":"Contraception"},{"key":"10.1016\/j.beem.2012.11.003_bib5","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1001\/archinte.164.7.741","article-title":"Risk of stroke in women exposed to low-dose oral contraceptives: a critical evaluation of the evidence","volume":"164","author":"Chan","year":"2004","journal-title":"Archives Internal Medicine"},{"key":"10.1016\/j.beem.2012.11.003_bib6","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1001\/jama.284.1.72","article-title":"Ischemic stroke risk with oral contraceptives: a meta-analysis","volume":"284","author":"Gillum","year":"2000","journal-title":"Journal of American Medical Association"},{"key":"10.1016\/j.beem.2012.11.003_bib7","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.1345\/aph.1Q216","article-title":"Estradiol valerate\/dienogest: a novel oral contraceptive","volume":"45","author":"Kl","year":"2011","journal-title":"Annals of Pharmacotherapy"},{"key":"10.1016\/j.beem.2012.11.003_bib8","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/j.steroids.2011.02.002","article-title":"Nomegestrol acetate, a novel progestogen for oral contraception","volume":"76","author":"Mueck","year":"2011","journal-title":"Steroids"},{"key":"10.1016\/j.beem.2012.11.003_bib9","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1016\/j.contraception.2010.04.004","article-title":"The use of newer progestins for contraception","volume":"82","author":"Sitruk-Ware","year":"2010","journal-title":"Contraception"},{"key":"10.1016\/j.beem.2012.11.003_bib10","doi-asserted-by":"crossref","first-page":"76","DOI":"10.3109\/13625187.2011.554923","article-title":"Inhibition of ovulation by NOMAC\/E2, a novel monophasic oral contraceptive combining nomegestrol acetate and 17\u03b2-oestradiol: a double-blind, randomised, dose-finding pilot study","volume":"16","author":"Chabbert-Buffet","year":"2011","journal-title":"European Journal of Contraception Reproductive Health Care"},{"key":"10.1016\/j.beem.2012.11.003_bib11","series-title":"Evidence-guided prescribing of the pill","article-title":"The pill: an historical overview","author":"Gillmer","year":"1996"},{"key":"10.1016\/j.beem.2012.11.003_bib12","doi-asserted-by":"crossref","first-page":"2257","DOI":"10.1056\/NEJMoa1111840","article-title":"Thrombotic stroke and myocardial infarction with hormonal contraception","volume":"366","author":"Lidegaard","year":"2012","journal-title":"New England Journal of Medicine"},{"key":"10.1016\/j.beem.2012.11.003_bib13","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1136\/jech.48.3.324","article-title":"Oral contraceptive use and risk of myocardial infarction: an Italian case-control study","volume":"48","author":"D'Avanzo","year":"1994","journal-title":"Journal of Epidemiology and Community Health"},{"key":"10.1016\/j.beem.2012.11.003_bib14","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/S0010-7824(97)00118-2","article-title":"The use of oral contraceptives and the occurrence of acute myocardial infarction in young women. Results from the transnational study on oral contraceptives and the health of young women","volume":"56","author":"Lewis","year":"1997","journal-title":"Contraception"},{"key":"10.1016\/j.beem.2012.11.003_bib15","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1016\/S0140-6736(97)02358-1","article-title":"Acute myocardial infarction and combined oral contraceptives: results of an international multicentre case-control study. WHO collaborative study of cardiovascular disease and steroid hormone contraception","volume":"349","author":"Anonymous","year":"1997","journal-title":"Lancet"},{"key":"10.1016\/j.beem.2012.11.003_bib16","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1161\/01.CIR.98.11.1058","article-title":"Myocardial infarction and use of low-dose oral contraceptives: a pooled analysis of 2 US studies","volume":"98","author":"Sidney","year":"1998","journal-title":"Circulation"},{"key":"10.1016\/j.beem.2012.11.003_bib17","doi-asserted-by":"crossref","first-page":"S357","DOI":"10.1016\/S0002-9378(99)70696-4","article-title":"Smoking and use of oral contraceptives: impact on thrombotic diseases","volume":"180","author":"Lidegaard","year":"1999","journal-title":"American Journal of Obstetrics and Gynecology"},{"key":"10.1016\/j.beem.2012.11.003_bib18","doi-asserted-by":"crossref","first-page":"1579","DOI":"10.1136\/bmj.318.7198.1579","article-title":"Oral contraceptives and myocardial infarction: results of the MICA case-control study","volume":"318","author":"Dunn","year":"1999","journal-title":"British Medical Journal"},{"key":"10.1016\/j.beem.2012.11.003_bib19","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1001\/archinte.161.8.1065","article-title":"Low-dose oral contraceptive use and the risk of myocardial infarction","volume":"161","author":"Rosenberg","year":"2001","journal-title":"Archives Internal Medicine"},{"key":"10.1016\/j.beem.2012.11.003_bib20","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1136\/jech.52.7.420","article-title":"Effects of changes in smoking status on risk estimates for myocardial infarction among women recruited for the Royal College of General Practitioners' Oral Contraception Study in the UK","volume":"52","author":"Owen-Smith","year":"1998","journal-title":"Journal of Epidemiology and Community Health"},{"key":"10.1016\/j.beem.2012.11.003_bib21","doi-asserted-by":"crossref","first-page":"1787","DOI":"10.1056\/NEJMoa003216","article-title":"Oral contraceptives and the risk of myocardial infarction","volume":"345","author":"Tanis","year":"2001","journal-title":"New England Journal of Medicine"},{"key":"10.1016\/j.beem.2012.11.003_bib22","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/j.fertnstert.2006.11.206","article-title":"A prospective study of oral contraceptive use and risk of myocardial infarction among Swedish women","volume":"88","author":"Margolis","year":"2007","journal-title":"Fertility and Sterility"},{"key":"10.1016\/j.beem.2012.11.003_bib23","doi-asserted-by":"crossref","first-page":"1510","DOI":"10.1093\/ije\/dyr134","article-title":"Reproductive history and mortality from cardiovascular disease among women textile workers in Shanghai, China","volume":"40","author":"Gallagher","year":"2011","journal-title":"International Journal of Epidemiology"},{"key":"10.1016\/j.beem.2012.11.003_bib24","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1136\/bmj.39555.441944.BE","article-title":"Hormone replacement therapy and risk of venous thromboembolism in postmenopausal women: systematic review and meta-analysis","volume":"336","author":"Canonico","year":"2008","journal-title":"British Medical Journal"},{"key":"10.1016\/j.beem.2012.11.003_bib25","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/S0010-7824(01)00172-X","article-title":"The relationship between use of oral contraceptives and myocardial infarction in young women with fatal outcome, compared to those who survive: results from the MICA case-control study","volume":"63","author":"Dunn","year":"2001","journal-title":"Contraception"},{"key":"10.1016\/j.beem.2012.11.003_bib26","unstructured":"FDA: combined hormonal contraceptives (chcs) and the risk of cardiovascular disease endpoints final report 111022v2. Available at: http:\/\/www.fda.gov\/downloads\/Drugs\/DrugSafety\/UCM277384.pdf"},{"key":"10.1016\/j.beem.2012.11.003_bib27","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1097\/01.AOG.0000250968.82370.04","article-title":"Venous thromboembolism, myocardial infarction, and stroke among transdermal contraceptive system users","volume":"109","author":"Cole","year":"2007","journal-title":"Obstetrics and Gynecology"},{"key":"10.1016\/j.beem.2012.11.003_bib28","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1210\/jc.2010-2065","article-title":"Progestogen-only contraceptives and the risk of acute myocardial infarction: a meta-analysis","volume":"96","author":"Chakhtoura","year":"2011","journal-title":"Journal of Clinical Endocrinology and Metabolism"},{"key":"10.1016\/j.beem.2012.11.003_bib29","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1016\/S1474-4422(08)70193-5","article-title":"Sex differences in stroke: epidemiology, clinical presentation, medical care, and outcomes","volume":"7","author":"Reeves","year":"2008","journal-title":"Lancet Neurology"},{"key":"10.1016\/j.beem.2012.11.003_bib30","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1136\/bmj.2.5313.1191-a","article-title":"Parietal lesion and enovid","volume":"2","author":"Lorentz","year":"1962","journal-title":"British Medical Journal"},{"key":"10.1016\/j.beem.2012.11.003_bib31","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1136\/bmj.2.5599.193","article-title":"Investigation of deaths from pulmonary, coronary, and cerebral thrombosis and embolism in women of child-bearing age","volume":"2","author":"Inman","year":"1968","journal-title":"British Medical Journal"},{"key":"10.1016\/j.beem.2012.11.003_bib32","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1161\/01.STR.25.5.935","article-title":"Oral contraception and stroke. Evidence from the Royal College of General Practitioners' oral contraception study","volume":"25","author":"Hannaford","year":"1994","journal-title":"Stroke"},{"key":"10.1016\/j.beem.2012.11.003_bib33","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1136\/bmj.306.6883.956","article-title":"Oral contraception and risk of a cerebral thromboembolic attack: results of a case-control study","volume":"306","author":"Lidegaard","year":"1993","journal-title":"British Medical Journal"},{"key":"10.1016\/j.beem.2012.11.003_bib34","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/0020-7292(86)90032-9","article-title":"Oral contraceptives and stroke: a preliminary report on an epidemiologic study in Taiwan, China","volume":"24","author":"Chang","year":"1986","journal-title":"International Journal of Gynecology and Obstetrics"},{"key":"10.1016\/j.beem.2012.11.003_bib35","doi-asserted-by":"crossref","first-page":"1468","DOI":"10.1136\/bmj.2.6203.1468","article-title":"Oral contraceptives and fatal subarachnoid haemorrhage","volume":"2","author":"Inman","year":"1979","journal-title":"British Medical Journal"},{"key":"10.1016\/j.beem.2012.11.003_bib36","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1016\/S0140-6736(95)12393-8","article-title":"Ischaemic stroke and combined oral contraceptives: results of an international, multicentre, case-control study. WHO collaborative study of cardiovascular disease and steroid hormone contraception","volume":"348","author":"Anonymous","year":"1996","journal-title":"Lancet"},{"key":"10.1016\/j.beem.2012.11.003_bib37","doi-asserted-by":"crossref","first-page":"1502","DOI":"10.1136\/bmj.315.7121.1502","article-title":"Case-control study of oral contraceptives and risk of thromboembolic stroke: results from international study on oral contraceptives and health of young women","volume":"315","author":"Heinemann","year":"1997","journal-title":"British Medical Journal"},{"key":"10.1016\/j.beem.2012.11.003_bib38","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1056\/NEJM199607043350102","article-title":"Stroke in users of low-dose oral contraceptives","volume":"335","author":"Petitti","year":"1996","journal-title":"New England Journal of Medicine"},{"key":"10.1016\/j.beem.2012.11.003_bib39","doi-asserted-by":"crossref","first-page":"2277","DOI":"10.1161\/01.STR.29.11.2277","article-title":"Stroke and use of low-dose oral contraceptives in young women: a pooled analysis of two US studies","volume":"29","author":"Schwartz","year":"1998","journal-title":"Stroke"},{"key":"10.1016\/j.beem.2012.11.003_bib40","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1161\/01.STR.28.1.26","article-title":"Lifestyle-associated risk factors for acute brain infarction among persons of working age","volume":"28","author":"Haapaniemi","year":"1997","journal-title":"Stroke"},{"key":"10.1016\/j.beem.2012.11.003_bib41","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S0010-7824(01)00306-7","article-title":"Contraceptives and cerebral thrombosis: a five-year national case-control study","volume":"65","author":"Lidegaard","year":"2002","journal-title":"Contraception"},{"key":"10.1016\/j.beem.2012.11.003_bib42","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1136\/bmj.310.6983.830","article-title":"Case-control study of migraine and risk of ischaemic stroke in young women","volume":"310","author":"Tzourio","year":"1995","journal-title":"British Medical Journal"},{"key":"10.1016\/j.beem.2012.11.003_bib43","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1161\/01.STR.0000015345.61324.3F","article-title":"Risk of Arterial Thrombosis in Relation to Oral Contraceptives (RATIO) study: oral contraceptives and the risk of ischemic stroke","volume":"33","author":"Kemmeren","year":"2002","journal-title":"Stroke"},{"key":"10.1016\/j.beem.2012.11.003_bib44","doi-asserted-by":"crossref","first-page":"1575","DOI":"10.1161\/01.STR.0000077925.16041.6B","article-title":"Risk of ischemic stroke among users of the oral contraceptive pill: the Melbourne Risk Factor Study (MERFS) Group","volume":"34","author":"Siritho","year":"2003","journal-title":"Stroke"},{"key":"10.1016\/j.beem.2012.11.003_bib45","doi-asserted-by":"crossref","first-page":"1574","DOI":"10.1161\/01.STR.0000129789.58837.e4","article-title":"Ischemic stroke in young women: a nested case-control study using the UK general practice research database","volume":"35","author":"Nightingale","year":"2004","journal-title":"Stroke"},{"key":"10.1016\/j.beem.2012.11.003_bib46","first-page":"844","article-title":"Oral contraceptive use, thrombophilia and their interaction in young women with ischemic stroke","volume":"91","author":"Martinelli","year":"2006","journal-title":"Haematologica"},{"key":"10.1016\/j.beem.2012.11.003_bib47","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1136\/jnnp.2006.101675","article-title":"Inherited thrombophilia and stratification of ischaemic stroke risk among users of oral contraceptives","volume":"78","author":"Pezzini","year":"2007","journal-title":"Journal of Neurology Neurosurgery and Psychiatry"},{"key":"10.1016\/j.beem.2012.11.003_bib48","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1161\/STROKEAHA.108.531913","article-title":"Reproductive history, oral contraceptive use, and the risk of ischemic and hemorrhagic stroke in a cohort study of middle-aged Swedish women","volume":"40","author":"Yang","year":"2009","journal-title":"Stroke"},{"key":"10.1016\/j.beem.2012.11.003_bib49","doi-asserted-by":"crossref","first-page":"E1319","DOI":"10.1503\/cmaj.110463","article-title":"Higher risk of venous thrombosis associated with drospirenone-containing oral contraceptives: a population-based cohort study","volume":"183","author":"Gronich","year":"2011","journal-title":"Canadian Medical Association Journal"},{"key":"10.1016\/j.beem.2012.11.003_bib50","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1016\/j.contraception.2009.12.009","article-title":"Extended case-control study results on thromboembolic outcomes among transdermal contraceptive users","volume":"81","author":"Dore","year":"2010","journal-title":"Contraception"},{"key":"10.1016\/j.beem.2012.11.003_bib51","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1783\/147118907781004750","article-title":"Migraine and use of combined hormonal contraceptives: a clinical review","volume":"33","author":"MacGregor","year":"2007","journal-title":"Journal of Family Planning and Reproductive Health Care"},{"key":"10.1016\/j.beem.2012.11.003_bib52","doi-asserted-by":"crossref","first-page":"b3914","DOI":"10.1136\/bmj.b3914","article-title":"Migraine and cardiovascular disease: systematic review and meta-analysis","volume":"339","author":"Sch\u00fcrks","year":"2009","journal-title":"British Medical Journal"},{"key":"10.1016\/j.beem.2012.11.003_bib53","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1046\/j.1468-2982.2000.00040.x","article-title":"Oral contraceptives and stroke","volume":"20","author":"Bousser","year":"2000","journal-title":"Cephalalgia"},{"key":"10.1016\/j.beem.2012.11.003_bib54","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1046\/j.1468-2982.2000.00035.x","volume":"20","author":"Bousser","year":"2000","journal-title":"Cephalalgia"},{"key":"10.1016\/j.beem.2012.11.003_bib55","series-title":"Multidisciplinary management of migraine","article-title":"Management specificities in female migraineurs","author":"Massiou","year":"2013"},{"key":"10.1016\/j.beem.2012.11.003_bib56","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1161\/STROKEAHA.108.538405","article-title":"Progestogen-only contraceptives and the risk of stroke","volume":"40","author":"Chakhtoura","year":"2009","journal-title":"Stroke"},{"key":"10.1016\/j.beem.2012.11.003_bib57","doi-asserted-by":"crossref","first-page":"2773","DOI":"10.1161\/01.STR.0000190838.02954.e8","article-title":"Risk factors for subarachnoid hemorrhage: an updated systematic review of epidemiological studies","volume":"36","author":"Feigin","year":"2005","journal-title":"Stroke"},{"key":"10.1016\/j.beem.2012.11.003_bib58","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/S0140-6736(95)12394-6","article-title":"Haemorrhagic stroke, overall stroke risk, and combined oral contraceptives: results of an international, multicentre, case-control study. WHO collaborative study of cardiovascular disease and steroid hormone contraception","volume":"348","author":"Anonymous","year":"1996","journal-title":"Lancet"},{"key":"10.1016\/j.beem.2012.11.003_bib59","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1002\/pds.1266","article-title":"Prospective cohort study of the association between use of low-dose oral contraceptives and stroke in Chinese women","volume":"15","author":"Li","year":"2006","journal-title":"Pharmacoepidemiol Drug Safety"}],"container-title":["Best Practice & Research Clinical Endocrinology & Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1521690X12001157?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1521690X12001157?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T16:45:49Z","timestamp":1761497149000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1521690X12001157"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,2]]},"references-count":59,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,2]]}},"alternative-id":["S1521690X12001157"],"URL":"https:\/\/doi.org\/10.1016\/j.beem.2012.11.003","relation":{},"ISSN":["1521-690X"],"issn-type":[{"value":"1521-690X","type":"print"}],"subject":[],"published":{"date-parts":[[2013,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hormonal contraceptives and arterial disease: An epidemiological update","name":"articletitle","label":"Article Title"},{"value":"Best Practice & Research Clinical Endocrinology & Metabolism","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.beem.2012.11.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}