{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T00:57:55Z","timestamp":1791075475604,"version":"4.1.0"},"reference-count":23,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2007,3,1]],"date-time":"2007-03-01T00:00:00Z","timestamp":1172707200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Best Practice & Research Clinical Haematology"],"published-print":{"date-parts":[[2007,3]]},"DOI":"10.1016\/j.beha.2006.10.006","type":"journal-article","created":{"date-parts":[[2007,3,1]],"date-time":"2007-03-01T21:29:55Z","timestamp":1172784595000},"page":"29-37","source":"Crossref","is-referenced-by-count":72,"title":["Is secondary leukemia an independent poor prognostic factor in acute myeloid leukemia?"],"prefix":"10.1016","volume":"20","author":[{"given":"Richard A.","family":"Larson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.beha.2006.10.006_bib1","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1007\/978-1-4615-1463-3_11","article-title":"Evolution of secondary hematologic disorders: preMDS-->MDS-->sAML","volume":"108","author":"Preisler","year":"2001","journal-title":"Cancer Treatment and Research"},{"key":"10.1016\/j.beha.2006.10.006_bib2","first-page":"937","article-title":"The incidence of secondary leukemias","volume":"84","author":"Leone","year":"1999","journal-title":"Haematologica"},{"key":"10.1016\/j.beha.2006.10.006_bib3","doi-asserted-by":"crossref","first-page":"3835","DOI":"10.1200\/JCO.1999.17.12.3835","article-title":"World Health Organization classification of neoplastic diseases of the hematopoietic and lymphoid tissues: report of the Clinical Advisory Committee meeting-Airlie House, Virginia, November 1997","volume":"17","author":"Harris","year":"1999","journal-title":"Journal of Clinical Oncology"},{"key":"10.1016\/j.beha.2006.10.006_bib4","series-title":"World Health Organization Classification of Tumours: Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues","first-page":"88","article-title":"Acute myeloid leukemia","author":"Brunning","year":"2001"},{"key":"10.1016\/j.beha.2006.10.006_bib5","series-title":"Hematologic Complications of Cancer","first-page":"293","article-title":"Therapy-related myeloid leukemia","volume":"10","author":"Thirman","year":"1996"},{"key":"10.1016\/j.beha.2006.10.006_bib6","series-title":"The Myelodysplastic Syndromes. Pathobiology and Clinical Management","first-page":"139","article-title":"The syndrome of therapy-related myelodysplasia and myeloid leukemia","author":"Godley","year":"2002"},{"key":"10.1016\/j.beha.2006.10.006_bib7","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1182\/blood-2003-11-3938","article-title":"Defective DNA mismatch repair in acute myeloid leukemia\/myelodysplastic syndrome after organ transplantation","volume":"104","author":"Offman","year":"2004","journal-title":"Blood"},{"key":"10.1016\/j.beha.2006.10.006_bib8","doi-asserted-by":"crossref","first-page":"1774","DOI":"10.1126\/science.1102443","article-title":"Hematotoxicity in workers exposed to low levels of benzene","volume":"306","author":"Lan","year":"2004","journal-title":"Science"},{"key":"10.1016\/j.beha.2006.10.006_bib9","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1056\/NEJM198704233161702","article-title":"Benzene and leukemia. An epidemiologic risk assessment","volume":"316","author":"Rinsky","year":"1987","journal-title":"The New England Journal of Medicine"},{"key":"10.1016\/j.beha.2006.10.006_bib10","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1016\/0140-6736(90)91071-H","article-title":"Radon as a causative factor in induction of myeloid leukaemia and other cancers","volume":"335","author":"Henshaw","year":"1990","journal-title":"Lancet"},{"key":"10.1016\/j.beha.2006.10.006_bib11","first-page":"639","article-title":"Correlation between selected environmental exposures and karyotype in acute myelocytic leukemia","volume":"5","author":"Crane","year":"1996","journal-title":"Cancer Epidemiology, Biomarkers and Prevention"},{"key":"10.1016\/j.beha.2006.10.006_bib12","doi-asserted-by":"crossref","first-page":"1637","DOI":"10.1200\/JCO.1989.7.11.1637","article-title":"Efficacy of intensive chemotherapy for acute myelogenous leukemia associated with a preleukemic syndrome","volume":"7","author":"Gajewski","year":"1989","journal-title":"Journal of Clinical Oncology"},{"key":"10.1016\/j.beha.2006.10.006_bib13","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1200\/JCO.2003.08.005","volume":"21","author":"Haferlach","year":"2003","journal-title":"Journal of Clinical Oncology"},{"key":"10.1016\/j.beha.2006.10.006_bib14","first-page":"520","article-title":"Evaluation of the dysmyelopoiesis in 336 patients with de novo acute myeloid leukemia: major importance of dysgranulopoiesis for remission and survival","volume":"6","author":"Goasguen","year":"1992","journal-title":"Leukemia"},{"key":"10.1016\/j.beha.2006.10.006_bib15","doi-asserted-by":"crossref","first-page":"3004","DOI":"10.1200\/JCO.2003.99.040","article-title":"Morphologic dysplasia in acute myeloid leukemia: importance of granulocytic dysplasia","volume":"21","author":"Bennett","year":"2003","journal-title":"Journal of Clinical Oncology"},{"key":"10.1016\/j.beha.2006.10.006_bib16","doi-asserted-by":"crossref","first-page":"3004","DOI":"10.1200\/JCO.2003.99.091","article-title":"Morphologic dysplasia in acute myeloid leukemia: importance of garnulcytic dysplasia","volume":"21","author":"Haferlach","year":"2003","journal-title":"Journal of Clinical Oncology"},{"key":"10.1016\/j.beha.2006.10.006_bib17","doi-asserted-by":"crossref","first-page":"2322","DOI":"10.1182\/blood.V92.7.2322","article-title":"The importance of diagnostic cytogenetics on outcome in AML: analysis of 1612 patients entered into the MRC AML10 trial","volume":"92","author":"Grimwade","year":"1998","journal-title":"Blood"},{"key":"10.1016\/j.beha.2006.10.006_bib18","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1182\/blood.V98.5.1312","article-title":"The predictive value of hierarchical cytogenetic classification in older adults with acute myeloid leukemia (AML): analysis of 1065 patients entered into the United Kingdom Medical Research Council AML11 trial","volume":"98","author":"Grimwade","year":"2001","journal-title":"Blood"},{"key":"10.1016\/j.beha.2006.10.006_bib19","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1182\/blood-2002-11-3343","article-title":"Clinical-cytogenetic associations in 306 patients with therapy-related myelodysplasia and myeloid leukemia: the University of Chicago series","volume":"102","author":"Smith","year":"2003","journal-title":"Blood"},{"key":"10.1016\/j.beha.2006.10.006_bib20","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1038\/sj.leu.2403187","article-title":"Karyotype is an independent prognostic parameter in therapy-related acute myeloid leukemia (t-AML): an analysis of 93 patients with t-AML in comparison to 1091 patients with de novo AML","volume":"18","author":"Schoch","year":"2004","journal-title":"Leukemia"},{"key":"10.1016\/j.beha.2006.10.006_bib21","doi-asserted-by":"crossref","first-page":"2510","DOI":"10.1200\/JCO.2004.99.301","article-title":"Prognosis in therapy-related acute myeloid leukemia and impact of karyotype","volume":"22","author":"Kern","year":"2004","journal-title":"Journal of Clinical Oncology"},{"key":"10.1016\/j.beha.2006.10.006_bib22","doi-asserted-by":"crossref","first-page":"1928","DOI":"10.1182\/blood-2002-03-0962","article-title":"Therapy-related MDS and AML in acute promyelocytic leukemia","volume":"100","author":"Andersen","year":"2002","journal-title":"Blood"},{"key":"10.1016\/j.beha.2006.10.006_bib23","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1002\/gcc.10043","article-title":"Balanced chromosome abnormalities inv(16) and t(15;17) in therapy-related myelodysplastic syndromes and acute leukemia: report from an international workshop","volume":"33","author":"Andersen","year":"2002","journal-title":"Genes Chromosomes Cancer"}],"container-title":["Best Practice & Research Clinical Haematology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1521692606000752?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1521692606000752?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,4,20]],"date-time":"2020-04-20T08:38:20Z","timestamp":1587371900000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1521692606000752"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,3]]},"references-count":23,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2007,3]]}},"alternative-id":["S1521692606000752"],"URL":"https:\/\/doi.org\/10.1016\/j.beha.2006.10.006","relation":{},"ISSN":["1521-6926"],"issn-type":[{"value":"1521-6926","type":"print"}],"subject":[],"published":{"date-parts":[[2007,3]]}}}