{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T03:15:08Z","timestamp":1789010108860,"version":"build-2803163510"},"reference-count":53,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,4,1]],"date-time":"2018-04-01T00:00:00Z","timestamp":1522540800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico (CNPq)"},{"name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior (CAPES)"},{"name":"Federal University of Santa Maria (UFSM)"},{"name":"Fundo de Incentivo \u00e0 Pesquisa (FIPE\/UFSM)"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Behavioural Processes"],"published-print":{"date-parts":[[2018,4]]},"DOI":"10.1016\/j.beproc.2018.01.020","type":"journal-article","created":{"date-parts":[[2018,2,2]],"date-time":"2018-02-02T03:33:53Z","timestamp":1517542433000},"page":"35-42","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":66,"special_numbering":"C","title":["Extending the analysis of zebrafish behavioral endophenotypes for modeling psychiatric disorders: Fear conditioning to conspecific alarm response"],"prefix":"10.1016","volume":"149","author":[{"given":"Caio","family":"Maximino","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniele L.","family":"Meinerz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara D.","family":"Fontana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathana J.","family":"Mezzomo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flavia V.","family":"Stefanello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"de S. Prestes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cibele B.","family":"Batista","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maribel A.","family":"Rubin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nilda V.","family":"Barbosa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo\u00e3o Batista T.","family":"Rocha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monica G.","family":"Lima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denis B.","family":"Rosemberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.beproc.2018.01.020_bib0005","first-page":"191","article-title":"Diagnostic and statistical manual of mental disorders (DSM)","volume":"25","author":"Battle","year":"2013","journal-title":"Codas"},{"key":"10.1016\/j.beproc.2018.01.020_bib0010","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/j.nlm.2009.07.001","article-title":"A one-trial inhibitory avoidance task to zebrafish: rapid acquisition of an NMDA-dependent long-term memory","volume":"92","author":"Blank","year":"2009","journal-title":"Neurobiol. Learn. Mem."},{"key":"10.1016\/j.beproc.2018.01.020_bib0015","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1037\/h0029561","article-title":"Effects of conditioned appetitive stimuli on the acquisition and extinction of a runway response","volume":"85","author":"Bolles","year":"1970","journal-title":"J. Exp. Psychol."},{"key":"10.1016\/j.beproc.2018.01.020_bib0020","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1192\/bjp.bp.111.096552","article-title":"Trajectories of trauma symptoms and resilience in deployed U.S. military service members: prospective cohort study","volume":"200","author":"Bonanno","year":"2012","journal-title":"Br. J. Psychiatry"},{"issue":"Suppl. 2","key":"10.1016\/j.beproc.2018.01.020_bib0025","doi-asserted-by":"crossref","first-page":"S101","DOI":"10.1590\/1516-4446-2013-1139","article-title":"Animal models of anxiety disorders and stress","volume":"35","author":"Campos","year":"2013","journal-title":"Rev. Bras. Psiquiatr."},{"key":"10.1016\/j.beproc.2018.01.020_bib0030","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.bbr.2016.12.018","article-title":"Conspecific alarm substance differently alters group behavior of zebrafish populations: putative involvement of cholinergic and purinergic signaling in anxiety- and fear-like responses","volume":"320","author":"Canzian","year":"2017","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.beproc.2018.01.020_bib0035","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.bbr.2014.05.005","article-title":"Modeling PTSD in the zebrafish: are we there yet?","volume":"276","author":"Caramillo","year":"2015","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.beproc.2018.01.020_bib0040","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1101\/lm.1676610","article-title":"The role of amygdala nuclei in the expression of auditory signaled two-way active avoidance in rats","volume":"17","author":"Choi","year":"2010","journal-title":"Learn. Mem."},{"key":"10.1016\/j.beproc.2018.01.020_bib0045","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.pnpbp.2014.05.014","article-title":"Zebrafish and conditioned place preference: a translational model of drug reward","volume":"55","author":"Collier","year":"2014","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.beproc.2018.01.020_bib0050","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1016\/j.pnpbp.2010.10.003","article-title":"Cross-species behavioural genetics: A starting point for unravelling the neurobiology of human psychiatric disorders","volume":"35","author":"de Mooij-van Malsen","year":"2011","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.beproc.2018.01.020_bib0055","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1901\/jeab.1977.28-83","article-title":"Escape, avoidance, punishment: where do we stand?","volume":"28","author":"Dinsmoor","year":"1977","journal-title":"J. Exp. Anal. Behav."},{"key":"10.1016\/j.beproc.2018.01.020_bib0060","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1901\/jeab.2001.75-311","article-title":"Stimuli inevitably generated by behavior that avoids electric shock are inherently reinforcing","volume":"75","author":"Dinsmoor","year":"2001","journal-title":"J. Exp. Anal. Behav."},{"key":"10.1016\/j.beproc.2018.01.020_bib0065","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1111\/j.1749-6632.2009.04111.x","article-title":"The alarm reaction in fishes--odorants, modulations of responses, neural pathways","volume":"1170","author":"Doving","year":"2009","journal-title":"Ann. N. Y. Acad. Sci."},{"issue":"1","key":"10.1016\/j.beproc.2018.01.020_bib0070","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.bbr.2009.06.022","article-title":"Understanding behavioral and physiological phenotypes of stress and anxiety in zebrafish","volume":"205","author":"Egan","year":"2009","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.beproc.2018.01.020_bib0075","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1101\/lm.034603.114","article-title":"Safety signals as instrumental reinforcers during free-operant avoidance","volume":"21","author":"Fernando","year":"2014","journal-title":"Learn. Mem."},{"key":"10.1016\/j.beproc.2018.01.020_bib0080","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1080\/10705510802339080","article-title":"Incorporating measurement non-equivalence in a cross-study latent growth curve analysis","volume":"15","author":"Flora","year":"2008","journal-title":"Struct. Equ. Model."},{"key":"10.1016\/j.beproc.2018.01.020_bib0085","doi-asserted-by":"crossref","first-page":"55","DOI":"10.3389\/fnbeh.2013.00055","article-title":"Heterogeneity in threat extinction learning: substantive and methodological considerations for identifying individual difference in response to stress","volume":"7","author":"Galatzer-Levy","year":"2013","journal-title":"Front. Behav. Neurosci."},{"key":"10.1016\/j.beproc.2018.01.020_bib0090","doi-asserted-by":"crossref","first-page":"179","DOI":"10.3389\/fnsys.2014.00179","article-title":"Heterogeneity in signaled active avoidance learning: substantive and methodological relevance of diversity in instrumental defensive responses to threat cues","volume":"8","author":"Galatzer-Levy","year":"2014","journal-title":"Front. Syst. Neurosci."},{"key":"10.1016\/j.beproc.2018.01.020_bib0095","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1037\/0735-7036.109.1.76","article-title":"Sensory preconditioning and second-order conditioning of alarm reactions in zebra danio fish (Brachydanio rerio)","volume":"109","author":"Hall","year":"1995","journal-title":"J. Comp. Psychol."},{"key":"10.1016\/j.beproc.2018.01.020_bib0100","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1006\/nlme.1995.1027","article-title":"Visual and olfactory stimuli in learned release of alarm reactions by zebra danio fish (Brachydanio rerio)","volume":"63","author":"Hall","year":"1995","journal-title":"Neurobiol. Learn. Mem."},{"key":"10.1016\/j.beproc.2018.01.020_bib0105","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1016\/j.neuropharm.2011.02.023","article-title":"Impaired safety signal learning may be a biomarker of PTSD","volume":"62","author":"Jovanovic","year":"2012","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.beproc.2018.01.020_bib0110","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1002\/da.20663","article-title":"Impaired fear inhibition is a biomarker of PTSD but not depression","volume":"27","author":"Jovanovic","year":"2010","journal-title":"Depress. Anxiety"},{"key":"10.1016\/j.beproc.2018.01.020_bib0115","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.psychres.2007.12.014","article-title":"Posttraumatic stress disorder may be associated with impaired fear inhibition: relation to symptom severity","volume":"167","author":"Jovanovic","year":"2009","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.beproc.2018.01.020_bib0120","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1089\/zeb.2012.0861","article-title":"Towards a comprehensive catalog of zebrafish behavior 1.0 and beyond","volume":"10","author":"Kalueff","year":"2013","journal-title":"Zebrafish"},{"key":"10.1016\/j.beproc.2018.01.020_bib0125","doi-asserted-by":"crossref","first-page":"189","DOI":"10.3389\/fnbeh.2015.00189","article-title":"Avoidance learning: a review of theoretical models and recent developments","volume":"9","author":"Krypotos","year":"2015","journal-title":"Front. Behav. Neurosci."},{"key":"10.1016\/j.beproc.2018.01.020_bib0130","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.aquaculture.2007.04.077","article-title":"The husbandry of zebrafish (Danio rerio): A review","volume":"269","author":"Lawrence","year":"2007","journal-title":"Aquaculture"},{"key":"10.1016\/j.beproc.2018.01.020_bib0135","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1038\/mp.2016.166","article-title":"The birth, death and resurrection of avoidance: a reconceptualization of a troubled paradigm","volume":"22","author":"LeDoux","year":"2017","journal-title":"Mol. Psychiatry"},{"issue":"Pt B","key":"10.1016\/j.beproc.2018.01.020_bib0140","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.pbb.2015.11.007","article-title":"Perspectives on zebrafish neurobehavioral pharmacology","volume":"139","author":"Levin","year":"2015","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.beproc.2018.01.020_bib0145","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.beproc.2016.04.009","article-title":"Time-dependent sensitization of stress responses in zebrafish: A putative model for post-traumatic stress disorder","volume":"128","author":"Lima","year":"2016","journal-title":"Behav. Processes"},{"issue":"Pt B","key":"10.1016\/j.beproc.2018.01.020_bib0150","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.pbb.2015.08.005","article-title":"Putative involvement of the nitrergic system on the consolidation, but not initiation, of behavioral sensitization after conspecific alarm substance in zebrafish","volume":"139","author":"Lima","year":"2015","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.beproc.2018.01.020_bib0155","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1089\/zeb.2013.0970","article-title":"Inhibitory avoidance learning in zebrafish (Danio rerio): effects of shock intensity and unraveling differences in task performance","volume":"11","author":"Manuel","year":"2014","journal-title":"Zebrafish"},{"key":"10.1016\/j.beproc.2018.01.020_bib0160","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1016\/j.cub.2012.01.061","article-title":"Chondroitin fragments are odorants that trigger fear behavior in fish","volume":"22","author":"Mathuru","year":"2012","journal-title":"Curr. Biol."},{"key":"10.1016\/j.beproc.2018.01.020_bib0165","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jchemneu.2012.10.001","article-title":"\"Limbic associative\" and \"autonomic\" amygdala in teleosts: a review of the evidence","volume":"48\u201349","author":"Maximino","year":"2013","journal-title":"J. Chem. Neuroanat."},{"key":"10.1016\/j.beproc.2018.01.020_bib0170","doi-asserted-by":"crossref","first-page":"233","DOI":"10.3389\/fnbeh.2015.00233","article-title":"Non-mammalian models in behavioral neuroscience: consequences for biological psychiatry","volume":"9","author":"Maximino","year":"2015","journal-title":"Front. Behav. Neurosci."},{"key":"10.1016\/j.beproc.2018.01.020_bib0175","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.neulet.2015.12.037","article-title":"The role of taurine on anxiety-like behaviors in zebrafish: A comparative study using the novel tank and the light-dark tasks","volume":"613","author":"Mezzomo","year":"2016","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.beproc.2018.01.020_bib0180","series-title":"Latent variable Analysis: Growth Mixture Modeling and Related Techniques for Longitudinal Data","article-title":"SAGE publications ltd.","author":"Muth\u00e9n","year":"2004"},{"key":"10.1016\/j.beproc.2018.01.020_bib0185","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1111\/jnc.13105","article-title":"Kisspeptin1 modulates odorant-evoked fear response via two serotonin receptor subtypes (5-HT1A and 5-HT2) in zebrafish","volume":"133","author":"Nathan","year":"2015","journal-title":"J. Neurochem."},{"key":"10.1016\/j.beproc.2018.01.020_bib0190","doi-asserted-by":"crossref","first-page":"3841","DOI":"10.1073\/pnas.1314184111","article-title":"Habenular kisspeptin modulates fear in the zebrafish","volume":"111","author":"Ogawa","year":"2014","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"2","key":"10.1016\/j.beproc.2018.01.020_bib0195","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1016\/j.bbr.2009.06.037","article-title":"The synthetic substance hypoxanthine3-N-oxide elicits alarm reactions in zebrafish (Danio rerio)","volume":"205","author":"Parra","year":"2009","journal-title":"Behav. Brain Res."},{"issue":"2","key":"10.1016\/j.beproc.2018.01.020_bib0200","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/j.pnpbp.2010.12.018","article-title":"Unpredictable chronic stress model in zebrafish (Danio rerio): behavioral and physiological responses","volume":"35","author":"Piato","year":"2011","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.beproc.2018.01.020_bib0205","doi-asserted-by":"crossref","first-page":"2335","DOI":"10.1523\/JNEUROSCI.4930-03.2004","article-title":"Avoidance response in goldfish: emotional and temporal involvement of medial and lateral telencephalic pallium","volume":"24","author":"Portavella","year":"2004","journal-title":"J. Neurosci."},{"key":"10.1016\/j.beproc.2018.01.020_bib0210","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.neulet.2004.01.083","article-title":"Lesions of the medial pallium, but not of the lateral pallium, disrupt spaced-trial avoidance learning in goldfish (Carassius auratus)","volume":"362","author":"Portavella","year":"2004","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.beproc.2018.01.020_bib0215","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1002\/sim.6731","article-title":"Joint modeling of repeated multivariate cognitive measures and competing risks of dementia and death: a latent process and latent class approach","volume":"35","author":"Proust-Lima","year":"2016","journal-title":"Stat. Med."},{"key":"10.1016\/j.beproc.2018.01.020_bib0220","series-title":"Methods of Behavior Analysis in Neuroscience","article-title":"Conditioned place preference","author":"Prus","year":"2009"},{"key":"10.1016\/j.beproc.2018.01.020_bib0225","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.beproc.2015.10.014","article-title":"Strain- and context-dependent behavioural responses of acute alarm substance exposure in zebrafish","volume":"122","author":"Quadros","year":"2016","journal-title":"Behav. Processes"},{"key":"10.1016\/j.beproc.2018.01.020_bib0230","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.pbb.2016.12.005","article-title":"Cannabinoid modulation of zebrafish fear learning and its functional analysis investigated by c-Fos expression","volume":"153","author":"Ruhl","year":"2017","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.beproc.2018.01.020_bib0235","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/j.psc.2009.06.001","article-title":"Posttraumatic stress disorder and stress-related disorders","volume":"32","author":"Shalev","year":"2009","journal-title":"Psychiatr. Clin. North Am."},{"key":"10.1016\/j.beproc.2018.01.020_bib0240","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1016\/j.pnpbp.2017.08.021","article-title":"Modeling consequences of prolonged strong unpredictable stress in zebrafish: complex effects on behavior and physiology","volume":"81","author":"Song","year":"2018","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.beproc.2018.01.020_bib0245","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.bbr.2007.10.031","article-title":"Alarm substance induced behavioral responses in zebrafish (Danio rerio)","volume":"188","author":"Speedie","year":"2008","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.beproc.2018.01.020_bib0250","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1038\/mp.2014.128","article-title":"Molecular psychiatry of zebrafish","volume":"20","author":"Stewart","year":"2015","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.beproc.2018.01.020_bib0255","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.pnpbp.2014.08.003","article-title":"Developing zebrafish models relevant to PTSD and other trauma- and stressor-related disorders","volume":"55","author":"Stewart","year":"2014","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.beproc.2018.01.020_bib0260","series-title":"Amygdala and Emotional Learning in Vertebrates \u2013 A Comparative Perspective","author":"Vargas","year":"2012"},{"key":"10.1016\/j.beproc.2018.01.020_bib0265","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1007\/BF01590598","article-title":"Zur psychologie des Fische-Schwarmes","volume":"26","author":"von Frisch","year":"1938","journal-title":"Naturwissenschaften"}],"container-title":["Behavioural Processes"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0376635717304801?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0376635717304801?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,8,24]],"date-time":"2018-08-24T08:56:16Z","timestamp":1535100976000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0376635717304801"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4]]},"references-count":53,"alternative-id":["S0376635717304801"],"URL":"https:\/\/doi.org\/10.1016\/j.beproc.2018.01.020","relation":{},"ISSN":["0376-6357"],"issn-type":[{"value":"0376-6357","type":"print"}],"subject":[],"published":{"date-parts":[[2018,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Extending the analysis of zebrafish behavioral endophenotypes for modeling psychiatric disorders: Fear conditioning to conspecific alarm response","name":"articletitle","label":"Article Title"},{"value":"Behavioural Processes","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.beproc.2018.01.020","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}