{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T04:36:38Z","timestamp":1788582998026,"version":"build-2803163510"},"reference-count":130,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2015,12,1]],"date-time":"2015-12-01T00:00:00Z","timestamp":1448928000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"KU Leuven internal funds","award":["StG\/15\/024"],"award-info":[{"award-number":["StG\/15\/024"]}]},{"DOI":"10.13039\/501100003130","name":"Flemish Research Foundation","doi-asserted-by":"publisher","award":["12N7615N"],"award-info":[{"award-number":["12N7615N"]}],"id":[{"id":"10.13039\/501100003130","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003130","name":"Flemish Research Foundation","doi-asserted-by":"publisher","award":["1.5.061.14"],"award-info":[{"award-number":["1.5.061.14"]}],"id":[{"id":"10.13039\/501100003130","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","bprclinrheum.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Best Practice & Research Clinical Rheumatology"],"published-print":{"date-parts":[[2015,12]]},"DOI":"10.1016\/j.berh.2016.02.001","type":"journal-article","created":{"date-parts":[[2016,3,14]],"date-time":"2016-03-14T22:50:56Z","timestamp":1457995856000},"page":"715-740","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"title":["Refine, reduce, replace: Imaging of fibrosis and arthritis in animal models"],"prefix":"10.1016","volume":"29","author":[{"given":"M.","family":"Marenzana","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Vande Velde","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.berh.2016.02.001_bib1","first-page":"47","article-title":"Non-invasive small rodent imaging- significance for the 3R principles","author":"Beckmann","year":"2010","journal-title":"Small Animal Imaging Springer Science & Business Media"},{"key":"10.1016\/j.berh.2016.02.001_bib2","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1186\/1465-9921-8-63","article-title":"Invasive and noninvasive methods for studying pulmonary function in mice","volume":"8","author":"Glaab","year":"2007","journal-title":"Respiratory Research"},{"key":"10.1016\/j.berh.2016.02.001_bib3","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.vascn.2006.04.006","article-title":"Invasive and noninvasive lung function measurements in rodents","volume":"55","author":"Hoymann","year":"2007","journal-title":"Journal of Pharmacological and Toxicological Methods"},{"key":"10.1016\/j.berh.2016.02.001_bib4","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1165\/rcmb.2008-0487OC","article-title":"Noninvasive and invasive pulmonary function in mouse models of obstructive and restrictive respiratory diseases","volume":"42","author":"Vanoirbeek","year":"2010","journal-title":"American Journal of Respiratory Cell and Molecular Biology"},{"key":"10.1016\/j.berh.2016.02.001_bib5","series-title":"Annual statistics of scientific procedures on living animals great Britain 2014","author":"Home Office","year":"2015"},{"key":"10.1016\/j.berh.2016.02.001_bib6","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1038\/nrrheum.2014.46","article-title":"Mouse models of osteoarthritis: modelling risk factors and assessing outcomes","volume":"10","author":"Fang","year":"2014","journal-title":"Nature Reviews Rheumatology"},{"key":"10.1016\/j.berh.2016.02.001_bib7","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1177\/0300985815588612","article-title":"Mouse models of rheumatoid Arthritis","volume":"52","author":"Caplazi","year":"2015","journal-title":"Veterinary Pathology"},{"key":"10.1016\/j.berh.2016.02.001_bib8","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.rdc.2007.11.002","article-title":"Fibrosis in systemic sclerosis","volume":"34","author":"Varga","year":"2008","journal-title":"Rheumatic Disease Clinics of North America"},{"key":"10.1016\/j.berh.2016.02.001_bib9","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.jbspin.2012.06.005","article-title":"Experimental models of dermal fibrosis and systemic sclerosis","volume":"80","author":"Avouac","year":"2013","journal-title":"Joint Bone Spine"},{"key":"10.1016\/j.berh.2016.02.001_bib10","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1111\/j.1346-8138.2009.00764.x","article-title":"Animal model of systemic sclerosis","volume":"37","author":"Yamamoto","year":"2010","journal-title":"The Journal of Dermatology"},{"key":"10.1016\/j.berh.2016.02.001_bib11","doi-asserted-by":"crossref","first-page":"L152","DOI":"10.1152\/ajplung.00313.2007","article-title":"Murine models of pulmonary fibrosis","volume":"294","author":"Moore","year":"2008","journal-title":"American Journal of Physiology - Lung Cellular and Molecular Physiology"},{"key":"10.1016\/j.berh.2016.02.001_bib12","doi-asserted-by":"crossref","first-page":"1537","DOI":"10.1172\/JCI11963","article-title":"TGF-beta is a critical mediator of acute lung injury","volume":"107","author":"Pittet","year":"2001","journal-title":"Journal of Clinical Investigation"},{"key":"10.1016\/j.berh.2016.02.001_bib13","doi-asserted-by":"crossref","first-page":"L439","DOI":"10.1152\/ajplung.00258.2010","article-title":"Bleomycin revisited: towards a more representative model of IPF?","volume":"299","author":"Scotton","year":"2010","journal-title":"American Journal of Physiology - Lung Cellular and Molecular Physiology"},{"key":"10.1016\/j.berh.2016.02.001_bib14","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1165\/rcmb.2005-0062TR","article-title":"Pulmonary fibrosis: searching for model answers","volume":"33","author":"Chua","year":"2005","journal-title":"American Journal of Respiratory Cell and Molecular Biology"},{"key":"10.1016\/j.berh.2016.02.001_bib15","first-page":"1648","article-title":"Bleomycin-induced chronic lung damage does not resemble human idiopathic pulmonary fibrosis","volume":"163","author":"Borzone","year":"2001","journal-title":"American Journal of Physiology - Lung Cellular and Molecular Physiology"},{"key":"10.1016\/j.berh.2016.02.001_bib16","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1016\/j.biocel.2007.08.011","article-title":"The bleomycin animal model: a useful tool to investigate treatment options for idiopathic pulmonary fibrosis?","volume":"40","author":"Moeller","year":"2008","journal-title":"The International Journal of Biochemistry & Cell Biology"},{"key":"10.1016\/j.berh.2016.02.001_bib17","doi-asserted-by":"crossref","first-page":"L442","DOI":"10.1152\/ajplung.00026.2010","article-title":"Repetitive intratracheal bleomycin models several features of idiopathic pulmonary fibrosis","volume":"299","author":"Degryse","year":"2010","journal-title":"American Journal of Physiology - Lung Cellular and Molecular Physiology"},{"key":"10.1016\/j.berh.2016.02.001_bib18","doi-asserted-by":"crossref","first-page":"R125","DOI":"10.1186\/ar4305","article-title":"Effect of sclerostin-neutralising antibody on periarticular and systemic bone in a murine model of rheumatoid arthritis: a microCT study","volume":"15","author":"Marenzana","year":"2013","journal-title":"Arthritis Research & Therapy"},{"key":"10.1016\/j.berh.2016.02.001_bib19","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/rr158","article-title":"A\u00a0new direction in the pathogenesis of idiopathic pulmonary fibrosis?","volume":"3","author":"Gauldie","year":"2002","journal-title":"Respiratory Research"},{"key":"10.1016\/j.berh.2016.02.001_bib20","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.autrev.2003.10.003","article-title":"Transgenic analysis of scleroderma: understanding key pathogenic events in\u00a0vivo","volume":"3","author":"Denton","year":"2004","journal-title":"Autoimmunity Reviews"},{"key":"10.1016\/j.berh.2016.02.001_bib21","doi-asserted-by":"crossref","first-page":"2367","DOI":"10.1161\/CIRCULATIONAHA.109.855114","article-title":"Transcription factor fos-related antigen-2 induces progressive peripheral vasculopathy in mice closely resembling human systemic sclerosis","volume":"120","author":"Maurer","year":"2009","journal-title":"Circulation"},{"key":"10.1016\/j.berh.2016.02.001_bib22","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.vph.2012.12.001","article-title":"The Fra-2 transgenic mouse model of systemic sclerosis","volume":"58","author":"Maurer","year":"2013","journal-title":"Vascular Pharmacology"},{"key":"10.1016\/j.berh.2016.02.001_bib23","doi-asserted-by":"crossref","first-page":"L897","DOI":"10.1152\/ajplung.00007.2014","article-title":"Preclinical anatomical, molecular, and functional imaging of the lung with multiple modalities","volume":"306","author":"Gammon","year":"2014","journal-title":"Am American Journal of Physiology - Lung Cellular and Molecular Physiology"},{"key":"10.1016\/j.berh.2016.02.001_bib24","doi-asserted-by":"crossref","first-page":"e43123","DOI":"10.1371\/journal.pone.0043123","article-title":"Quantification of lung fibrosis and emphysema in mice using automated micro-computed tomography","volume":"7","author":"De Langhe","year":"2012","journal-title":"PloS One"},{"issue":"1","key":"10.1016\/j.berh.2016.02.001_bib25","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1242\/dmm.020321","article-title":"Longitudinal micro-CT provides biomarkers of lung disease that can be used to assess the effect of therapy in preclinical mouse models, and reveal compensatory changes in lung volume","volume":"9","author":"Vande Velde","year":"2016","journal-title":"Disease Models & Mechanisms"},{"key":"10.1016\/j.berh.2016.02.001_bib26","doi-asserted-by":"crossref","first-page":"2600","DOI":"10.1007\/s00330-010-1853-0","article-title":"Longitudinal study of a mouse model of chronic pulmonary inflammation using breath hold gated micro-CT","volume":"20","author":"Artaechevarria","year":"2010","journal-title":"European Radiology"},{"key":"10.1016\/j.berh.2016.02.001_bib27","doi-asserted-by":"crossref","first-page":"3324","DOI":"10.1118\/1.1812604","article-title":"Micro-CT with respiratory and cardiac gating","volume":"31","author":"Badea","year":"2004","journal-title":"Medical Physics"},{"key":"10.1016\/j.berh.2016.02.001_bib28","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1097\/00004728-200311000-00001","article-title":"Magnetic resonance: an introduction to ultrashort TE (UTE) imaging","volume":"27","author":"Robson","year":"2003","journal-title":"Journal of Computer Assisted Tomography"},{"key":"10.1016\/j.berh.2016.02.001_bib29","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1002\/jmri.21100","article-title":"Bleomycin-induced lung injury assessed noninvasively and in spontaneously breathing rats by proton MRI","volume":"26","author":"Karmouty-Quintana","year":"2007","journal-title":"Journal of Magnetic Resonance Imaging"},{"key":"10.1016\/j.berh.2016.02.001_bib30","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1002\/jmri.22476","article-title":"Noninvasive assessment of bleomycin-induced lung injury and the effects of short-term glucocorticosteroid treatment in rats using MRI","volume":"33","author":"Babin","year":"2011","journal-title":"Journal of Magnetic Resonance Imaging"},{"key":"10.1016\/j.berh.2016.02.001_bib31","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1002\/jmri.22166","article-title":"In\u00a0vivo MRI of altered proton signal intensity and T2 relaxation in a bleomycin model of pulmonary inflammation and fibrosis","volume":"31","author":"Jacob","year":"2010","journal-title":"Journal of Magnetic Resonance Imaging"},{"key":"10.1016\/j.berh.2016.02.001_bib32","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1002\/mrm.23009","article-title":"Bleomycin-induced lung injury in mice investigated by MRI: model assessment for target analysis","volume":"67","author":"Babin","year":"2012","journal-title":"Magnetic Resonance in Medicine"},{"key":"10.1016\/j.berh.2016.02.001_bib33","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1097\/RLI.0000000000000071","volume":"49","author":"Vande Velde","year":"2014","journal-title":"Investigative Radiology"},{"key":"10.1016\/j.berh.2016.02.001_bib34","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1148\/radiology.179.3.2027991","article-title":"Lung parenchyma: projection reconstruction MR imaging","volume":"179","author":"Bergin","year":"1991","journal-title":"Radiology"},{"key":"10.1016\/j.berh.2016.02.001_bib35","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1002\/jmri.24232","article-title":"Pulmonary 3 T MRI with ultrashort TEs: influence of ultrashort echo time interval on pulmonary functional and clinical stage assessments of smokers","volume":"39","author":"Ohno","year":"2014","journal-title":"Journal of Magnetic Resonance Imaging"},{"key":"10.1016\/j.berh.2016.02.001_bib36","article-title":"Three-dimensional assessment of lung tissue density using a clinical ultrashort echo time at 3 tesla: a feasibility study in healthy subjects","volume":"40","author":"Lederlin","year":"2013","journal-title":"Journal of Magnetic Resonance Imaging"},{"key":"10.1016\/j.berh.2016.02.001_bib37","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1002\/mrm.22360","article-title":"Validation of simple and robust protocols for high-resolution lung proton MRI in mice","volume":"64","author":"Zurek","year":"2010","journal-title":"Magnetic Resonance in Medicine"},{"key":"10.1016\/j.berh.2016.02.001_bib38","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1002\/jmri.22267","article-title":"Ultra-short echo time (UTE) MR imaging of the lung: comparison between normal and emphysematous lungs in mutant mice","volume":"32","author":"Takahashi","year":"2010","journal-title":"Journal of Magnetic Resonance Imaging"},{"key":"10.1016\/j.berh.2016.02.001_bib39","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1097\/RLI.0b013e3182a53111","article-title":"Assessing lung transplantation ischemia-reperfusion injury by microcomputed tomography and ultrashort echo-time magnetic resonance imaging in a mouse model","volume":"49","author":"Wurnig","year":"2014","journal-title":"Investigative Radiology"},{"key":"10.1016\/j.berh.2016.02.001_bib40","doi-asserted-by":"crossref","first-page":"L1064","DOI":"10.1152\/ajplung.00027.2014","article-title":"Lung volume quantified by MRI reflects extracellular-matrix deposition and altered pulmonary function in bleomycin models of fibrosis: effects of SOM230","volume":"306","author":"Egger","year":"2014","journal-title":"American Journal of Physiology - Lung Cellular and Molecular Physiology"},{"key":"10.1016\/j.berh.2016.02.001_bib41","doi-asserted-by":"crossref","first-page":"18278","DOI":"10.1073\/pnas.0608458103","article-title":"Imaging alveolar-capillary gas transfer using hyperpolarized 129Xe MRI","volume":"103","author":"Driehuys","year":"2006","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"10.1016\/j.berh.2016.02.001_bib42","doi-asserted-by":"crossref","first-page":"1468","DOI":"10.1002\/jbmr.141","article-title":"Guidelines for assessment of bone microstructure in rodents using micro-computed tomography","volume":"25","author":"Bouxsein","year":"2010","journal-title":"Journal of Bone and Mineral Research"},{"key":"10.1016\/j.berh.2016.02.001_bib43","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1002\/art.23277","article-title":"A\u00a0type I collagen defect leads to rapidly progressive osteoarthritis in a mouse model","volume":"58","author":"Blair-Levy","year":"2008","journal-title":"Arthritis & Rheumatology"},{"key":"10.1016\/j.berh.2016.02.001_bib44","first-page":"246","article-title":"Characterization of bleomycin lung injury by nuclear magnetic resonance: correlation between NMR relaxation times and lung water and collagen content","volume":"47","author":"Cutillo","year":"2002","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"10.1016\/j.berh.2016.02.001_bib45","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1097\/00004424-199901000-00003","article-title":"Differentiation of alveolitis and pulmonary fibrosis in rabbits with magnetic resonance imaging after intrabronchial administration of bleomycin","volume":"34","author":"Kersjes","year":"1999","journal-title":"Investigative Radiology"},{"key":"10.1016\/j.berh.2016.02.001_bib46","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1097\/00004424-198708000-00001","article-title":"Proton relaxation times in bleomycin-induced lung injury","volume":"22","author":"Taylor","year":"1987","journal-title":"Investigative Radiology"},{"key":"10.1016\/j.berh.2016.02.001_bib47","first-page":"413","article-title":"Cis-4-[(18)F]fluoro-L-proline PET imaging of pulmonary fibrosis in a rabbit model","volume":"43","author":"Wallace","year":"2002","journal-title":"Journal of Nuclear Medicine"},{"key":"10.1016\/j.berh.2016.02.001_bib48","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/j.taap.2005.02.027","article-title":"Positron emission tomography in the quantification of cellular and biochemical responses to intrapulmonary particulates","volume":"207","author":"Jones","year":"2005","journal-title":"Toxicology and Applied Pharmacology"},{"key":"10.1016\/j.berh.2016.02.001_bib49","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1164\/ajrccm.158.2.9711075","article-title":"Pulmonary fibrosis correlates with duration of tissue neutrophil activation","volume":"158","author":"Jones","year":"1998","journal-title":"American Journal of Respiratory and Critical Care Medicine"},{"key":"10.1016\/j.berh.2016.02.001_bib50","doi-asserted-by":"crossref","first-page":"e33397","DOI":"10.1371\/journal.pone.0033397","article-title":"Altered trabecular bone structure and delayed cartilage degeneration in the knees of collagen VI null mice","volume":"7","author":"Christensen","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.berh.2016.02.001_bib51","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1007\/s004080000051","article-title":"Morphological and biochemical properties of alveolar fibroblasts in interstitial lung diseases","volume":"179","author":"Fireman","year":"2001","journal-title":"Lung"},{"key":"10.1016\/j.berh.2016.02.001_bib52","doi-asserted-by":"crossref","first-page":"538","DOI":"10.2967\/jnumed.108.057901","article-title":"Idiopathic pulmonary fibrosis and diffuse parenchymal lung disease: implications from initial experience with 18F-FDG PET\/CT","volume":"50","author":"Groves","year":"2009","journal-title":"Journal of Nuclear Medicine"},{"key":"10.1016\/j.berh.2016.02.001_bib53","doi-asserted-by":"crossref","first-page":"e107999","DOI":"10.1371\/journal.pone.0107999","article-title":"Comparison of methods to reduce myocardial 18F-FDG uptake in mice: calcium channel blockers versus high-fat diets","volume":"9","author":"Cuss\u00f3","year":"2014","journal-title":"PloS One"},{"key":"10.1016\/j.berh.2016.02.001_bib54","first-page":"145","article-title":"18F-FDG imaging: pitfalls and artifacts","volume":"33","author":"Abouzied","year":"2005","journal-title":"Journal of Nuclear Medicine Technology"},{"key":"10.1016\/j.berh.2016.02.001_bib55","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1165\/rcmb.2015-0032TR","article-title":"Noninvasive imaging of experimental lung fibrosis","volume":"53","author":"Zhou","year":"2015","journal-title":"American Journal of Respiratory Cell and Molecular Biology"},{"key":"10.1016\/j.berh.2016.02.001_bib56","doi-asserted-by":"crossref","first-page":"2237","DOI":"10.1021\/mp300613x","article-title":"Non-invasive monitoring of pulmonary fibrosis by targeting matrix metalloproteinases (MMPs)","volume":"10","author":"Cai","year":"2013","journal-title":"Molecular Pharmaceutics"},{"key":"10.1016\/j.berh.2016.02.001_bib57","doi-asserted-by":"crossref","first-page":"064017","DOI":"10.1117\/1.2400702","article-title":"Time-resolved imaging of optical coefficients through murine chest cavities","volume":"11","author":"Niedre","year":"2006","journal-title":"Journal of Biomedical Optics"},{"key":"10.1016\/j.berh.2016.02.001_bib58","first-page":"556","article-title":"Pre-clinical optical molecular imaging in the lung: technological challenges and future prospects","volume":"4","author":"Dimarzio","year":"2012","journal-title":"Journal of Thoracic Disease"},{"key":"10.1016\/j.berh.2016.02.001_bib59","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1186\/1465-9921-11-181","article-title":"Micro-computed tomography of pulmonary fibrosis in mice induced by adenoviral gene transfer of biologically active transforming growth factor-beta1","volume":"11","author":"Rodt","year":"2010","journal-title":"Respiratory Research"},{"key":"10.1016\/j.berh.2016.02.001_bib60","doi-asserted-by":"crossref","DOI":"10.1002\/nbm.3142","article-title":"In\u00a0vivo MRI for effective non-invasive detection and follow-up of an orthotopic mouse model of lung cancer","volume":"27","author":"Bianchi","year":"2014","journal-title":"NMR in Biomedicine"},{"key":"10.1016\/j.berh.2016.02.001_bib61","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1097\/BOR.0b013e32834518a3","article-title":"Pathophysiology of rheumatoid arthritis","volume":"23","author":"Cooles","year":"2011","journal-title":"Current Opinion in Rheumatology"},{"key":"10.1016\/j.berh.2016.02.001_bib62","doi-asserted-by":"crossref","first-page":"2205","DOI":"10.1056\/NEJMra1004965","article-title":"The pathogenesis of rheumatoid arthritis","volume":"365","author":"McInnes","year":"2011","journal-title":"The New England Journal of Medicine"},{"key":"10.1016\/j.berh.2016.02.001_bib63","doi-asserted-by":"crossref","first-page":"1697","DOI":"10.1002\/art.34453","article-title":"Osteoarthritis: a disease of the joint as an organ","volume":"64","author":"Loeser","year":"2012","journal-title":"Arthritis & Rheumatology"},{"key":"10.1016\/j.berh.2016.02.001_bib64","doi-asserted-by":"crossref","first-page":"1654","DOI":"10.1093\/rheumatology\/keq154","article-title":"In\u00a0vivo high-resolution MRI (7T) of femoro-tibial cartilage changes in the rat anterior cruciate ligament transection model of osteoarthritis: a cross-sectional study","volume":"49","author":"Goebel","year":"2010","journal-title":"Rheumatology (Oxford)"},{"key":"10.1016\/j.berh.2016.02.001_bib65","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1258\/la.2007.06041e","article-title":"In\u00a0vivo magnetic resonance imaging of animal models of knee osteoarthritis","volume":"42","author":"Wang","year":"2008","journal-title":"Laboratory Animals"},{"key":"10.1016\/j.berh.2016.02.001_bib66","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1007\/s00330-004-2486-y","article-title":"Early changes in experimental osteoarthritis using the Pond-Nuki dog model: technical procedure and initial results of in\u00a0vivo MR imaging","volume":"15","author":"Libicher","year":"2005","journal-title":"European Radiology"},{"key":"10.1016\/j.berh.2016.02.001_bib67","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1002\/jmri.22867","article-title":"Quantitative cartilage degeneration associated with spontaneous osteoarthritis in a guinea pig model","volume":"35","author":"Fenty","year":"2011","journal-title":"Journal of Magnetic Resonance Imaging"},{"key":"10.1016\/j.berh.2016.02.001_bib68","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1016\/j.joca.2004.03.002","article-title":"High-resolution MRI and micro-CT in an ex\u00a0vivo rabbit anterior cruciate ligament transection model of osteoarthritis","volume":"12","author":"Batiste","year":"2004","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.berh.2016.02.001_bib69","doi-asserted-by":"crossref","first-page":"1378","DOI":"10.1016\/j.joca.2007.04.012","article-title":"Non-invasive in\u00a0vivo quantification of the medial tibial cartilage thickness progression in an osteoarthritis rabbit model with quantitative 3D high resolution micro-MRI","volume":"15","author":"Boulocher","year":"2007","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.berh.2016.02.001_bib70","doi-asserted-by":"crossref","first-page":"247","DOI":"10.3233\/BME-2008-0533","article-title":"In\u00a0vivo rat knee cartilage volume measurement using quantitative high resolution MRI (7 T): feasibility and reproducibility","volume":"18","author":"Goebel","year":"2008","journal-title":"Bio-Medical Materials and Engineering"},{"key":"10.1016\/j.berh.2016.02.001_bib71","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.jot.2015.06.002","article-title":"In\u00a0vivo three-dimensional magnetic resonance imaging of rat knee osteoarthritis model induced using meniscal transection","author":"Wang","year":"2015","journal-title":"Journal of Orthopaedic Translation"},{"key":"10.1016\/j.berh.2016.02.001_bib72","doi-asserted-by":"crossref","first-page":"4024","DOI":"10.1002\/art.23128","article-title":"Longitudinal assessment of synovial, lymph node, and bone volumes in inflammatory arthritis in mice by in\u00a0vivo magnetic resonance imaging and microfocal computed tomography","volume":"56","author":"Proulx","year":"2007","journal-title":"Arthritis & Rheumatology"},{"key":"10.1016\/j.berh.2016.02.001_bib73","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1002\/jbmr.2392","article-title":"Validation of power Doppler versus contrast-enhanced magnetic resonance imaging quantification of joint inflammation in murine inflammatory arthritis","volume":"30","author":"Bouta","year":"2015","journal-title":"Journal of Bone and Mineral Research"},{"key":"10.1016\/j.berh.2016.02.001_bib74","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1016\/j.mri.2015.06.007","article-title":"Using 7.0T MRI T2 mapping to detect early changes of the cartilage matrix caused by immobilization in a rabbit model of immobilization-induced osteoarthritis","volume":"33","author":"Wei","year":"2015","journal-title":"Magnetic Resonance Imaging"},{"key":"10.1016\/j.berh.2016.02.001_bib75","doi-asserted-by":"crossref","first-page":"e76658","DOI":"10.1371\/journal.pone.0076658","article-title":"Sequential change in T2* values of cartilage, meniscus, and subchondral bone marrow in a rat model of knee osteoarthritis","volume":"8","author":"Tsai","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.berh.2016.02.001_bib76","doi-asserted-by":"crossref","first-page":"R26","DOI":"10.1186\/ar3727","article-title":"An in\u00a0vivo investigation of the initiation and progression of subchondral cysts in a rodent model of secondary osteoarthritis","volume":"14","author":"McErlain","year":"2012","journal-title":"Arthritis Research & Therapy"},{"key":"10.1016\/j.berh.2016.02.001_bib77","doi-asserted-by":"crossref","first-page":"2726","DOI":"10.1002\/art.27595","article-title":"In\u00a0vivo microfocal computed tomography and micro-magnetic resonance imaging evaluation of antiresorptive and antiinflammatory drugs as preventive treatments of osteoarthritis in the rat","volume":"62","author":"Jones","year":"2010","journal-title":"Arthritis & Rheumatology"},{"key":"10.1016\/j.berh.2016.02.001_bib78","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/j.bone.2007.04.184","article-title":"Blockade of beta-adrenergic signaling does not influence the bone mechano-adaptive response in mice","volume":"41","author":"Marenzana","year":"2007","journal-title":"Bone"},{"key":"10.1016\/j.berh.2016.02.001_bib79","first-page":"379","article-title":"Quantification of subchondral bone changes in a murine osteoarthritis model using micro-CT","author":"Botter","year":"2006","journal-title":"Biorheology"},{"key":"10.1016\/j.berh.2016.02.001_bib80","doi-asserted-by":"crossref","first-page":"2690","DOI":"10.1002\/art.30307","article-title":"Osteoarthritis induction leads to early and temporal subchondral plate porosity in the tibial plateau of mice: an in\u00a0vivo microfocal computed tomography study","volume":"63","author":"Botter","year":"2011","journal-title":"Arthritis & Rheumatology"},{"key":"10.1016\/j.berh.2016.02.001_bib81","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/j.bone.2015.07.035","article-title":"Phospho1 deficiency transiently modifies bone architecture yet produces consistent modification in osteocyte differentiation and vascular porosity with ageing","volume":"81","author":"Javaheri","year":"2015","journal-title":"Bone"},{"key":"10.1016\/j.berh.2016.02.001_bib82","doi-asserted-by":"crossref","first-page":"R210","DOI":"10.1186\/ar3543","article-title":"Application of in\u00a0vivo micro-computed tomography in the temporal characterisation of subchondral bone architecture in a rat model of low-dose monosodium iodoacetate-induced osteoarthritis","volume":"13","author":"Mohan","year":"2011","journal-title":"Arthritis Research & Therapy"},{"key":"10.1016\/j.berh.2016.02.001_bib83","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.bone.2014.06.009","article-title":"Inhibited osteoclastic bone resorption through alendronate treatment in rats reduces severe osteoarthritis progression","volume":"66","author":"Siebelt","year":"2014","journal-title":"Bone"},{"key":"10.1016\/j.berh.2016.02.001_bib84","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1016\/j.joca.2014.07.014","article-title":"Rapid, automated imaging of mouse articular cartilage by microCT for early detection of osteoarthritis and finite element modelling of joint mechanics","volume":"22","author":"Das Neves Borges","year":"2014","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.berh.2016.02.001_bib85","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1016\/j.rcl.2009.04.005","article-title":"CT arthrography, MR arthrography, PET, and scintigraphy in osteoarthritis","volume":"47","author":"Omoumi","year":"2009","journal-title":"Radiologic Clinics of North America"},{"key":"10.1016\/j.berh.2016.02.001_bib86","doi-asserted-by":"crossref","first-page":"19255","DOI":"10.1073\/pnas.0606406103","article-title":"Analysis of cartilage matrix fixed charge density and three-dimensional morphology via contrast-enhanced microcomputed tomography","volume":"103","author":"Palmer","year":"2006","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"10.1016\/j.berh.2016.02.001_bib87","doi-asserted-by":"crossref","first-page":"1788","DOI":"10.1002\/jor.21444","article-title":"Quantifying osteoarthritic cartilage changes accurately using in\u00a0vivo microCT arthrography in three etiologically distinct rat models","volume":"29","author":"Siebelt","year":"2011","journal-title":"Journal of Orthopaedic Research"},{"key":"10.1016\/j.berh.2016.02.001_bib88","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1002\/art.37766","article-title":"Quantitative imaging of murine osteoarthritic cartilage by phase-contrast micro-computed tomography","volume":"65","author":"Ruan","year":"2013","journal-title":"Arthritis & Rheumatology"},{"key":"10.1016\/j.berh.2016.02.001_bib89","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1177\/1947603513501175","article-title":"Contrast-enhanced nanofocus X-ray computed tomography allows virtual three-dimensional histopathology and morphometric analysis of osteoarthritis in small animal models","volume":"5","author":"Kerckhofs","year":"2014","journal-title":"Cartilage"},{"key":"10.1016\/j.berh.2016.02.001_bib90","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1016\/j.joca.2011.02.018","article-title":"Summary and recommendations of the OARSI FDA osteoarthritis assessment of structural change working group","volume":"19","author":"Conaghan","year":"2011","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.berh.2016.02.001_bib91","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1016\/j.joca.2013.02.652","article-title":"Spontaneous osteoarthritis in Str\/ort mice is unlikely due to greater vulnerability to mechanical trauma","author":"Poulet","year":"2013","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.berh.2016.02.001_bib92","article-title":"Quantification of cortical bone loss and repair for therapeutic evaluation in collagen-induced arthritis, by micro\u2013computed tomography and automated image analysis","volume":"50","author":"Barck","year":"2004","journal-title":"Arthritis & Rheumatology"},{"key":"10.1016\/j.berh.2016.02.001_bib93","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/j.bone.2007.07.007","article-title":"Automatic segmentation of cortical and trabecular compartments based on a dual threshold technique for in\u00a0vivo micro-CT bone analysis","volume":"41","author":"Buie","year":"2007","journal-title":"Bone"},{"key":"10.1016\/j.berh.2016.02.001_bib94","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.bone.2014.11.014","article-title":"Development and optimization of a high-throughput micro-computed tomography imaging method incorporating a novel analysis technique to evaluate bone mineral density of arthritic joints in a rodent model of collagen induced arthritis","volume":"73","author":"Sevilla","year":"2015","journal-title":"Bone"},{"key":"10.1016\/j.berh.2016.02.001_bib95","doi-asserted-by":"crossref","first-page":"1630","DOI":"10.1038\/ijo.2015.113","article-title":"Fully-automated, high-throughput micro-computed tomography analysis of body composition enables therapeutic efficacy monitoring in preclinical models","volume":"39","author":"Wyatt","year":"2015","journal-title":"International Journal of Obesity"},{"key":"10.1016\/j.berh.2016.02.001_bib96","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1109\/TMI.2009.2024743","article-title":"Automatic segmentation and quantitative analysis of the articular cartilages from magnetic resonance images of the knee","volume":"29","author":"Fripp","year":"2010","journal-title":"IEEE Transactions on Medical Imaging"},{"key":"10.1016\/j.berh.2016.02.001_bib97","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1016\/j.joca.2012.04.012","article-title":"Initial application of EPIC-\u03bcCT to assess mouse articular cartilage morphology and composition: effects of aging and treadmill running","volume":"20","author":"Kotwal","year":"2012","journal-title":"Osteoarthritis and Cartilage"},{"key":"10.1016\/j.berh.2016.02.001_bib98","doi-asserted-by":"crossref","first-page":"8406","DOI":"10.1002\/anie.201404519","article-title":"Tantalum oxide nanoparticles for the imaging of articular cartilage using X-ray computed tomography: visualization of ex\u00a0vivo\/in\u00a0vivo murine tibia","volume":"53","author":"Freedman","year":"2014","journal-title":"Angewandte Chemie International Edition"},{"key":"10.1016\/j.berh.2016.02.001_bib99","doi-asserted-by":"crossref","first-page":"S17","DOI":"10.1016\/j.joca.2010.05.025","article-title":"The OARSI histopathology initiative - recommendations for histological assessments of osteoarthritis in the mouse","volume":"18","author":"Glasson","year":"2010","journal-title":"Osteoarthritis and Cartilage"},{"key":"10.1016\/j.berh.2016.02.001_bib100","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1136\/ard.16.4.494","article-title":"Radiological assessment of osteo-arthrosis","volume":"16","author":"Kellgren","year":"1957","journal-title":"Annals of the Rheumatic Diseases"},{"key":"10.1016\/j.berh.2016.02.001_bib101","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.1109\/TMI.2010.2047653","article-title":"Anatomically corresponded regional analysis of cartilage in asymptomatic and osteoarthritic knees by statistical shape modelling of the bone","volume":"29","author":"Williams","year":"2010","journal-title":"IEEE Transactions on Medical Imaging"},{"key":"10.1016\/j.berh.2016.02.001_bib102","first-page":"1","article-title":"Quantitative 3D analysis of bone in hip osteoarthritis using clinical computed tomography","author":"Turmezei","year":"2015","journal-title":"European Radiology"},{"key":"10.1016\/j.berh.2016.02.001_bib103","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/j.bone.2010.10.007","article-title":"In\u00a0vivo micro-computed tomography allows direct three-dimensional quantification of both bone formation and bone resorption parameters using time-lapsed imaging","volume":"48","author":"Schulte","year":"2011","journal-title":"Bone"},{"key":"10.1016\/j.berh.2016.02.001_bib104","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/j.bone.2015.07.037","article-title":"Quantification of skeletal growth, modeling, and remodeling by in\u00a0vivo micro computed tomography","volume":"81","author":"Altman","year":"2015","journal-title":"Bone"},{"key":"10.1016\/j.berh.2016.02.001_bib105","doi-asserted-by":"crossref","first-page":"S260","DOI":"10.1016\/j.joca.2014.02.493","article-title":"Fast-throughput assessment of osteophyte growth in murine osteoarthritis for cross-sectional or longitudinal microct studies","author":"Borges","year":"2014","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.berh.2016.02.001_bib106","doi-asserted-by":"crossref","first-page":"866","DOI":"10.3109\/02841851.2010.504742","article-title":"Phase-contrast X-ray imaging of breast","volume":"51","author":"Keyrilainen","year":"2010","journal-title":"Acta Radiologica"},{"key":"10.1016\/j.berh.2016.02.001_bib107","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1053\/joca.2001.0496","article-title":"Diffraction-enhanced X-ray imaging of articular cartilage","volume":"10","author":"Mollenhauer","year":"2002","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.berh.2016.02.001_bib108","doi-asserted-by":"crossref","first-page":"7649","DOI":"10.1088\/0031-9155\/55\/24\/017","article-title":"In\u00a0vivo x-ray phase contrast analyzer-based imaging for longitudinal osteoarthritis studies in guinea pigs","volume":"55","author":"Coan","year":"2010","journal-title":"Physics in Medicine and Biology"},{"key":"10.1016\/j.berh.2016.02.001_bib109","doi-asserted-by":"crossref","first-page":"76224O","DOI":"10.1117\/12.843655","article-title":"Bone cartilage imaging with x-ray interferometry using a practical x-ray tube","volume":"7622","author":"Kido","year":"2010","journal-title":"Proceedings of SPIE"},{"key":"10.1016\/j.berh.2016.02.001_bib110","doi-asserted-by":"crossref","first-page":"5697","DOI":"10.1088\/0031-9155\/56\/17\/015","article-title":"Talbot phase-contrast x-ray imaging for the small joints of the hand","volume":"56","author":"Stutman","year":"2011","journal-title":"Physics in Medicine and Biology"},{"key":"10.1016\/j.berh.2016.02.001_bib111","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/j.acra.2009.09.015","article-title":"Articular cartilage imaging by the use of phase-contrast tomography in a collagen-induced arthritis mouse model","volume":"17","author":"Lee","year":"2010","journal-title":"Academic Radiology"},{"key":"10.1016\/j.berh.2016.02.001_bib112","doi-asserted-by":"crossref","first-page":"074106","DOI":"10.1063\/1.2772193","article-title":"A\u00a0coded-aperture technique allowing x-ray phase contrast imaging with conventional sources","volume":"91","author":"Olivo","year":"2007","journal-title":"Applied Physics Letters"},{"key":"10.1016\/j.berh.2016.02.001_bib113","doi-asserted-by":"crossref","first-page":"8173","DOI":"10.1088\/0031-9155\/57\/24\/8173","article-title":"Visualization of small lesions in rat cartilage by means of laboratory-based x-ray phase contrast imaging","volume":"57","author":"Marenzana","year":"2012","journal-title":"Physics in Medicine and Biology"},{"key":"10.1016\/j.berh.2016.02.001_bib114","doi-asserted-by":"crossref","first-page":"20130127","DOI":"10.1098\/rsta.2013.0127","article-title":"Synchrotron- and laboratory-based X-ray phase-contrast imaging for imaging mouse articular cartilage in the absence of radiopaque contrast agents","volume":"372","author":"Marenzana","year":"2014","journal-title":"Philosophical Transactions of the Royal Society A: Mathematical, Physical & Engineering Sciences"},{"key":"10.1016\/j.berh.2016.02.001_bib115","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1007\/s11926-012-0266-2","article-title":"Role of ultrasound in managing rheumatoid arthritis","volume":"14","author":"Hammer","year":"2012","journal-title":"Current Rheumatology Reports"},{"key":"10.1016\/j.berh.2016.02.001_bib116","doi-asserted-by":"crossref","first-page":"e89484","DOI":"10.1371\/journal.pone.0089484","article-title":"Ultrasound can detect macroscopically undetectable changes in osteoarthritis reflecting the superficial histological and biochemical degeneration: ex\u00a0vivo study of rabbit and human cartilage","volume":"9","author":"Nishitani","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.berh.2016.02.001_bib117","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1038\/nrrheum.2012.148","article-title":"Emerging optical and nuclear medicine imaging methods in rheumatoid arthritis","volume":"8","author":"Mountz","year":"2012","journal-title":"Nature Reviews Rheumatology"},{"key":"10.1016\/j.berh.2016.02.001_bib118","doi-asserted-by":"crossref","first-page":"3824","DOI":"10.1002\/art.30628","article-title":"Early diagnosis of arthritis in mice with collagen-induced arthritis, using a fluorogenic matrix metalloproteinase 3-specific polymeric probe","volume":"63","author":"Ryu","year":"2011","journal-title":"Arthritis & Rheumatology"},{"key":"10.1016\/j.berh.2016.02.001_bib119","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1002\/art.38295","article-title":"In\u00a0vivo imaging of matrix metalloproteinase 12 and matrix metalloproteinase 13 activities in the mouse model of collagen-induced arthritis","volume":"66","author":"Lim","year":"2014","journal-title":"Arthritis & Rheumatology"},{"key":"10.1016\/j.berh.2016.02.001_bib120","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/2191-219X-1-11","article-title":"Imaging technologies for preclinical models of bone and joint disorders","volume":"1","author":"Tremoleda","year":"2011","journal-title":"EJNMMI Research"},{"key":"10.1016\/j.berh.2016.02.001_bib121","doi-asserted-by":"crossref","first-page":"R310","DOI":"10.1186\/ar1483","article-title":"Arthritis imaging using a near-infrared fluorescence folate-targeted probe","volume":"7","author":"Chen","year":"2005","journal-title":"Arthritis Research & Therapy"},{"key":"10.1016\/j.berh.2016.02.001_bib122","doi-asserted-by":"crossref","first-page":"R37","DOI":"10.1186\/ar4191","article-title":"Evaluation of the novel folate receptor ligand [18F]fluoro-PEG-folate for macrophage targeting in a rat model of arthritis","volume":"15","author":"Gent","year":"2013","journal-title":"Arthritis Research & Therapy"},{"key":"10.1016\/j.berh.2016.02.001_bib123","doi-asserted-by":"crossref","first-page":"807","DOI":"10.2967\/jnumed.112.111781","article-title":"SPECT imaging of joint inflammation with Nanobodies targeting the macrophage mannose receptor in a mouse model for rheumatoid arthritis","volume":"54","author":"Put","year":"2013","journal-title":"Journal of Nuclear Medicine"},{"key":"10.1016\/j.berh.2016.02.001_bib124","doi-asserted-by":"crossref","first-page":"467","DOI":"10.2967\/jnumed.115.162628","article-title":"Monitoring therapy response of experimental arthritis with radiolabeled tracers targeting fibroblasts, macrophages or integrin alphavbeta3","volume":"57","author":"Terry","year":"2015","journal-title":"Journal of Nuclear Medicine"},{"key":"10.1016\/j.berh.2016.02.001_bib125","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1002\/art.30082","article-title":"In\u00a0vivo fluorescence imaging of E-selectin: quantitative detection of endothelial activation in a mouse model of arthritis","volume":"63","author":"Gompels","year":"2011","journal-title":"Arthritis & Rheumatology"},{"key":"10.1016\/j.berh.2016.02.001_bib126","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1186\/s13075-015-0832-x","article-title":"A\u00a0novel method to detect articular chondrocyte death during early stages of osteoarthritis using a non-invasive ApoPep-1 probe","volume":"17","author":"Che","year":"2015","journal-title":"Arthritis Research & Therapy"},{"key":"10.1016\/j.berh.2016.02.001_bib127","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1186\/s13075-015-0565-x","article-title":"Non-invasive in\u00a0vivo imaging of arthritis in a collagen-induced murine model with phosphatidylserine-binding near-infrared (NIR) dye","volume":"17","author":"Chan","year":"2015","journal-title":"Arthritis Research & Therapy"},{"key":"10.1016\/j.berh.2016.02.001_bib128","doi-asserted-by":"crossref","first-page":"1898","DOI":"10.1002\/art.30363","article-title":"Imaging of activated macrophages in experimental osteoarthritis using folate-targeted animal single-photon-emission computed tomography\/computed tomography","volume":"63","author":"Piscaer","year":"2011","journal-title":"Arthritis & Rheumatology"},{"key":"10.1016\/j.berh.2016.02.001_bib129","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.jim.2009.06.009","article-title":"Use of biofluorescence imaging to compare the distribution of certolizumab pegol, adalimumab, and infliximab in the inflamed paws of mice with collagen-induced arthritis","volume":"348","author":"Palframan","year":"2009","journal-title":"Journal of Immunological Methods"},{"key":"10.1016\/j.berh.2016.02.001_bib130","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1186\/ar4542","article-title":"Molecular imaging of rheumatoid arthritis: emerging markers, tools, and techniques","volume":"16","author":"Put","year":"2014","journal-title":"Arthritis Research & Therapy"}],"container-title":["Best Practice & Research Clinical Rheumatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1521694216000036?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1521694216000036?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,6,15]],"date-time":"2022-06-15T03:52:40Z","timestamp":1655265160000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1521694216000036"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12]]},"references-count":130,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2015,12]]}},"alternative-id":["S1521694216000036"],"URL":"https:\/\/doi.org\/10.1016\/j.berh.2016.02.001","relation":{},"ISSN":["1521-6942"],"issn-type":[{"value":"1521-6942","type":"print"}],"subject":[],"published":{"date-parts":[[2015,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Refine, reduce, replace: Imaging of fibrosis and arthritis in animal models","name":"articletitle","label":"Article Title"},{"value":"Best Practice & Research Clinical Rheumatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.berh.2016.02.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}