{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,10]],"date-time":"2026-11-10T17:34:55Z","timestamp":1794332095731,"version":"4.9.0"},"reference-count":147,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2017,12,1]],"date-time":"2017-12-01T00:00:00Z","timestamp":1512086400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["ZO1-AR041184"],"award-info":[{"award-number":["ZO1-AR041184"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.fr","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Best Practice &amp; Research Clinical Rheumatology"],"published-print":{"date-parts":[[2017,12]]},"DOI":"10.1016\/j.berh.2018.07.012","type":"journal-article","created":{"date-parts":[[2018,8,23]],"date-time":"2018-08-23T01:22:28Z","timestamp":1534987348000},"page":"797-815","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":54,"title":["The role of HLA-B*27 in spondyloarthritis"],"prefix":"10.1016","volume":"31","author":[{"given":"Robert A.","family":"Colbert","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatemeh","family":"Navid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tejpal","family":"Gill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5393","key":"10.1016\/j.berh.2018.07.012_bib1","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1038\/242121a0","article-title":"Human lymphocyte antigen association in ankylosing spondylitis","volume":"242","author":"Caffrey","year":"1973","journal-title":"Nature"},{"key":"10.1016\/j.berh.2018.07.012_bib2","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1056\/NEJM197304052881403","article-title":"High association of an HL-A antigen, W27, with ankylosing spondylitis","volume":"288","author":"Schlosstein","year":"1973","journal-title":"N\u00a0Engl J Med"},{"issue":"5","key":"10.1016\/j.berh.2018.07.012_bib3","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1038\/ng.3528","article-title":"Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci","volume":"48","author":"Ellinghaus","year":"2016","journal-title":"Nat Genet"},{"issue":"2","key":"10.1016\/j.berh.2018.07.012_bib4","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/j.immuni.2017.02.007","article-title":"Mass spectrometry profiling of hla-associated peptidomes in mono-allelic cells enables more accurate epitope prediction","volume":"46","author":"Abelin","year":"2017","journal-title":"Immunity"},{"issue":"2","key":"10.1016\/j.berh.2018.07.012_bib5","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1002\/art.27257","article-title":"The HLA-B*2705 peptidome","volume":"62","author":"Ben Dror","year":"2010","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.berh.2018.07.012_bib6","doi-asserted-by":"crossref","first-page":"6879","DOI":"10.1073\/pnas.90.14.6879","article-title":"Allele-specific B pocket transplant in class I major histocompatibility complex protein changes requirement for anchor residue at P2 of peptide","volume":"90","author":"Colbert","year":"1993","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.berh.2018.07.012_bib7","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1002\/eji.1830270205","article-title":"Susceptibility to ankylosing spondylitis correlates with the C-terminal residue of peptides presented by various HLA-B27 subtypes","volume":"27","author":"Fiorillo","year":"1997","journal-title":"Eur J Immunol"},{"key":"10.1016\/j.berh.2018.07.012_bib8","article-title":"The peptide repertoire of HLA-B27 may include ligands with lysine at P2 anchor position","volume":"8","author":"Yair-Sabag","year":"2018","journal-title":"Proteomics"},{"key":"10.1016\/j.berh.2018.07.012_bib9","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1146\/annurev.iy.13.040195.003103","article-title":"The three-dimensional structure of peptide-MHC complexes","volume":"13","author":"Madden","year":"1995","journal-title":"Annu Rev Immunol"},{"issue":"2","key":"10.1016\/j.berh.2018.07.012_bib10","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1038\/nm0297-212","article-title":"Late escape from an immunodominant cytotoxic T-lymphocyte response associated with progression to AIDS","volume":"3","author":"Goulder","year":"1997","journal-title":"Nat Med"},{"issue":"6844","key":"10.1016\/j.berh.2018.07.012_bib11","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1038\/35085576","article-title":"Evolution and transmission of stable CTL escape mutations in HIV infection","volume":"412","author":"Goulder","year":"2001","journal-title":"Nature"},{"issue":"2","key":"10.1016\/j.berh.2018.07.012_bib12","first-page":"89","article-title":"Progression of HIV to AIDS: a protective role for HLA-B27?","volume":"6","author":"den Uyl","year":"2004","journal-title":"AIDS Rev"},{"issue":"2","key":"10.1016\/j.berh.2018.07.012_bib13","first-page":"376","article-title":"Loss of viral fitness and cross-recognition by CD8+ T cells limit HCV escape from a protective HLA-B27-restricted human immune response","volume":"119","author":"Dazert","year":"2009","journal-title":"J\u00a0Clin Invest"},{"issue":"4","key":"10.1016\/j.berh.2018.07.012_bib14","doi-asserted-by":"crossref","first-page":"1585","DOI":"10.1084\/jem.184.4.1585","article-title":"A\u00a0p70 killer cell inhibitory receptor specific for several HLA-B allotypes discriminates among peptides bound to HLA-B*2705","volume":"184","author":"Peruzzi","year":"1996","journal-title":"J\u00a0Exp Med"},{"issue":"5200","key":"10.1016\/j.berh.2018.07.012_bib15","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1126\/science.7863326","article-title":"Peptide specificity in the recognition of MHC class I by natural killer cell clones","volume":"267","author":"Malnati","year":"1995","journal-title":"Science"},{"issue":"2","key":"10.1016\/j.berh.2018.07.012_bib16","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1002\/eji.200425724","article-title":"Crystal structures and KIR3DL1 recognition of three immunodominant viral peptides complexed to HLA-B*2705","volume":"35","author":"Stewart-Jones","year":"2005","journal-title":"Eur J Immunol"},{"key":"10.1016\/j.berh.2018.07.012_bib17","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1146\/annurev-immunol-032414-112110","article-title":"HLA-B27","volume":"33","author":"Bowness","year":"2015","journal-title":"Annu Rev Immunol"},{"issue":"7","key":"10.1016\/j.berh.2018.07.012_bib18","doi-asserted-by":"crossref","first-page":"3096","DOI":"10.4049\/jimmunol.160.7.3096","article-title":"Human myelomonocytic cells express an inhibitory receptor for classical and nonclassical MHC class I molecules","volume":"160","author":"Colonna","year":"1998","journal-title":"J\u00a0Immunol"},{"issue":"2","key":"10.1016\/j.berh.2018.07.012_bib19","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/s11926-017-0640-1","article-title":"An update on the genetic polymorphism of HLA-B*27 with 213 alleles encompassing 160 subtypes (and still counting)","volume":"19","author":"Khan","year":"2017","journal-title":"Curr Rheumatol Rep"},{"key":"10.1016\/j.berh.2018.07.012_bib20","first-page":"1111","article-title":"HLA-B27 subtypes positively and negatively associated with spondyloarthropathy","volume":"24","author":"Nasution","year":"1997","journal-title":"J\u00a0Rheumatol"},{"key":"10.1016\/j.berh.2018.07.012_bib21","doi-asserted-by":"crossref","first-page":"3199","DOI":"10.1002\/eji.1830251133","article-title":"Relevance of residue 116 of HLA-B27 in determining susceptibility to ankylosing spondylitis","volume":"25","author":"D'Amato","year":"1995","journal-title":"Eur J Immunol"},{"key":"10.1016\/j.berh.2018.07.012_bib22","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1136\/ard.59.8.654a","article-title":"The HLA-B*2709 subtype in a patient with undifferentiated spondarthritis","volume":"59","author":"Olivieri","year":"2000","journal-title":"Ann Rheum Dis"},{"issue":"2","key":"10.1016\/j.berh.2018.07.012_bib23","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1002\/art.10127","article-title":"The HLA-B*2709 subtype confers susceptibility to spondylarthropathy","volume":"46","author":"Olivieri","year":"2002","journal-title":"Arthritis Rheum"},{"issue":"8","key":"10.1016\/j.berh.2018.07.012_bib24","doi-asserted-by":"crossref","first-page":"2805","DOI":"10.1002\/art.22821","article-title":"The HLA-B*2709 subtype in a woman with early ankylosing spondylitis","volume":"56","author":"Olivieri","year":"2007","journal-title":"Arthritis Rheum"},{"issue":"10","key":"10.1016\/j.berh.2018.07.012_bib25","doi-asserted-by":"crossref","first-page":"3319","DOI":"10.1002\/art.21308","article-title":"Distribution of HLA-B27 subtypes in Sardinia and continental Italy and their association with spondylarthropathies","volume":"52","author":"Paladini","year":"2005","journal-title":"Arthritis Rheum"},{"issue":"1","key":"10.1016\/j.berh.2018.07.012_bib26","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1111\/j.0105-2896.2009.00865.x","article-title":"From HLA-B27 to spondyloarthritis: a journey through the ER","volume":"233","author":"Colbert","year":"2010","journal-title":"Immunol Rev"},{"issue":"8","key":"10.1016\/j.berh.2018.07.012_bib27","doi-asserted-by":"crossref","first-page":"E1006","DOI":"10.1073\/pnas.1519894113","article-title":"Interaction of TAPBPR, a tapasin homolog, with MHC-I molecules promotes peptide editing","volume":"113","author":"Morozov","year":"2016","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"6366","key":"10.1016\/j.berh.2018.07.012_bib28","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1126\/science.aao6001","article-title":"Structure of the TAPBPR-MHC I complex defines the mechanism of peptide loading and editing","volume":"358","author":"Thomas","year":"2017","journal-title":"Science"},{"issue":"6366","key":"10.1016\/j.berh.2018.07.012_bib29","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1126\/science.aao5154","article-title":"Crystal structure of a TAPBPR-MHC I complex reveals the mechanism of peptide editing in antigen presentation","volume":"358","author":"Jiang","year":"2017","journal-title":"Science"},{"key":"10.1016\/j.berh.2018.07.012_bib30","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.coi.2017.04.008","article-title":"Properties of the tapasin homologue TAPBPR","volume":"46","author":"Neerincx","year":"2017","journal-title":"Curr Opin Immunol"},{"key":"10.1016\/j.berh.2018.07.012_bib31","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.coi.2017.03.015","article-title":"The ongoing saga of the mechanism(s) of MHC class I-restricted cross-presentation","volume":"46","author":"Grotzke","year":"2017","journal-title":"Curr Opin Immunol"},{"issue":"8","key":"10.1016\/j.berh.2018.07.012_bib32","doi-asserted-by":"crossref","first-page":"4178","DOI":"10.4049\/jimmunol.170.8.4178","article-title":"Regulation of MHC class I transport in human dendritic cells and the dendritic-like cell line KG-1","volume":"170","author":"Ackerman","year":"2003","journal-title":"J\u00a0Immunol"},{"issue":"6956","key":"10.1016\/j.berh.2018.07.012_bib33","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1038\/nature01912","article-title":"Phagosomes are competent organelles for antigen cross-presentation","volume":"425","author":"Houde","year":"2003","journal-title":"Nature"},{"issue":"6956","key":"10.1016\/j.berh.2018.07.012_bib34","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1038\/nature01911","article-title":"ER-phagosome fusion defines an MHC class I cross-presentation compartment in dendritic cells","volume":"425","author":"Guermonprez","year":"2003","journal-title":"Nature"},{"issue":"6","key":"10.1016\/j.berh.2018.07.012_bib35","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1016\/j.cell.2011.11.021","article-title":"Sec22b regulates phagosomal maturation and antigen crosspresentation by dendritic cells","volume":"147","author":"Cebrian","year":"2011","journal-title":"Cell"},{"issue":"5195","key":"10.1016\/j.berh.2018.07.012_bib36","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1126\/science.7809629","article-title":"A\u00a0phagosome-to-cytosol pathway for exogenous antigens presented on MHC class I molecules","volume":"267","author":"Kovacsovics-Bankowski","year":"1995","journal-title":"Science"},{"issue":"2","key":"10.1016\/j.berh.2018.07.012_bib37","doi-asserted-by":"crossref","first-page":"983","DOI":"10.4049\/jimmunol.177.2.983","article-title":"Role of immunoproteasomes in cross-presentation","volume":"177","author":"Palmowski","year":"2006","journal-title":"J\u00a0Immunol"},{"issue":"4","key":"10.1016\/j.berh.2018.07.012_bib38","doi-asserted-by":"crossref","first-page":"2241","DOI":"10.4049\/jimmunol.178.4.2241","article-title":"The role of endoplasmic reticulum-associated aminopeptidase 1 in immunity to infection and in cross-presentation","volume":"178","author":"Firat","year":"2007","journal-title":"J\u00a0Immunol"},{"issue":"24","key":"10.1016\/j.berh.2018.07.012_bib39","doi-asserted-by":"crossref","first-page":"21906","DOI":"10.1074\/jbc.M111.239111","article-title":"Secretion of endoplasmic reticulum aminopeptidase 1 is involved in the activation of macrophages induced by lipopolysaccharide and interferon-gamma","volume":"286","author":"Goto","year":"2011","journal-title":"J\u00a0Biol Chem"},{"issue":"9","key":"10.1016\/j.berh.2018.07.012_bib40","doi-asserted-by":"crossref","first-page":"4443","DOI":"10.4049\/jimmunol.1300935","article-title":"TLR-mediated secretion of endoplasmic reticulum aminopeptidase 1 from macrophages","volume":"192","author":"Goto","year":"2014","journal-title":"J\u00a0Immunol"},{"issue":"6","key":"10.1016\/j.berh.2018.07.012_bib41","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1093\/jb\/mvv001","article-title":"Substrate-dependent nitric oxide synthesis by secreted endoplasmic reticulum aminopeptidase 1 in macrophages","volume":"157","author":"Goto","year":"2015","journal-title":"J\u00a0Biochem"},{"issue":"6","key":"10.1016\/j.berh.2018.07.012_bib42","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1016\/j.bbamcr.2018.03.009","article-title":"Contribution of the exosome-associated form of secreted endoplasmic reticulum aminopeptidase 1 to exosome-mediated macrophage activation","volume":"1865","author":"Goto","year":"2018","journal-title":"Biochim Biophys Acta"},{"issue":"2","key":"10.1016\/j.berh.2018.07.012_bib43","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.immuni.2004.07.004","article-title":"Important role of cathepsin S in generating peptides for TAP-independent MHC class I crosspresentation in\u00a0vivo","volume":"21","author":"Shen","year":"2004","journal-title":"Immunity"},{"issue":"5937","key":"10.1016\/j.berh.2018.07.012_bib44","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1126\/science.1172845","article-title":"IRAP identifies an endosomal compartment required for MHC class I cross-presentation","volume":"325","author":"Saveanu","year":"2009","journal-title":"Science"},{"issue":"1","key":"10.1016\/j.berh.2018.07.012_bib45","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.molimm.2013.07.013","article-title":"HLA-B27 misfolding and ankylosing spondylitis","volume":"57","author":"Colbert","year":"2014","journal-title":"Mol Immunol"},{"key":"10.1016\/j.berh.2018.07.012_bib46","doi-asserted-by":"crossref","first-page":"23459","DOI":"10.1074\/jbc.M110336200","article-title":"HLA-B27 misfolding is associated with aberrant intermolecular disulfide bond formation (dimerization) in the endoplasmic reticulum","volume":"277","author":"Dangoria","year":"2002","journal-title":"J\u00a0Biol Chem"},{"issue":"8","key":"10.1016\/j.berh.2018.07.012_bib47","doi-asserted-by":"crossref","first-page":"5110","DOI":"10.4049\/jimmunol.172.8.5110","article-title":"HLA-B27 in transgenic rats forms disulfide-linked heavy chain oligomers and multimers that bind to the chaperone BiP","volume":"172","author":"Tran","year":"2004","journal-title":"J\u00a0Immunol"},{"issue":"5","key":"10.1016\/j.berh.2018.07.012_bib48","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1002\/art.40414","article-title":"The role of autophagy in the degradation of misfolded HLA-B27 heavy chains","volume":"70","author":"Navid","year":"2018","journal-title":"Arthritis Rheum"},{"issue":"1","key":"10.1016\/j.berh.2018.07.012_bib49","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1089\/ars.2010.3693","article-title":"The MHC Class I heavy chain structurally conserved cysteines 101 and 164 participate in HLA-B27 dimer formation","volume":"16","author":"Lenart","year":"2012","journal-title":"Antioxidants Redox Signal"},{"issue":"4","key":"10.1016\/j.berh.2018.07.012_bib50","doi-asserted-by":"crossref","first-page":"2438","DOI":"10.4049\/jimmunol.175.4.2438","article-title":"HLA-B27 misfolding in transgenic rats is associated with activation of the unfolded protein response","volume":"175","author":"Turner","year":"2005","journal-title":"J\u00a0Immunol"},{"issue":"1","key":"10.1016\/j.berh.2018.07.012_bib51","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1002\/art.22295","article-title":"HLA-B27 up-regulation causes accumulation of misfolded heavy chains and correlates with the magnitude of the unfolded protein response in transgenic rats: implications for the pathogenesis of spondylarthritis-like disease","volume":"56","author":"Turner","year":"2007","journal-title":"Arthritis Rheum"},{"issue":"3\u20134","key":"10.1016\/j.berh.2018.07.012_bib52","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1007\/s002510050596","article-title":"The role of HLA-B27 in spondyloarthritis","volume":"50","author":"Allen","year":"1999","journal-title":"Immunogenetics"},{"key":"10.1016\/j.berh.2018.07.012_bib53","doi-asserted-by":"crossref","first-page":"2972","DOI":"10.1002\/art.10605","article-title":"Cell surface expression and immune receptor recognition of HLA-B27 homodimers","volume":"46","author":"Kollnberger","year":"2002","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.berh.2018.07.012_bib54","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1002\/eji.200323678","article-title":"Lymphoblastoid cells express HLA-B27 homodimers both intracellularly and at the cell surface following endosomal recycling","volume":"33","author":"Bird","year":"2003","journal-title":"Eur J Immunol"},{"issue":"1","key":"10.1016\/j.berh.2018.07.012_bib55","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1038\/nrrheum.2016.192","article-title":"Causes and consequences of endoplasmic reticulum stress in rheumatic disease","volume":"13","author":"Navid","year":"2017","journal-title":"Nat Rev Rheumatol"},{"issue":"1","key":"10.1016\/j.berh.2018.07.012_bib56","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1111\/jnc.12493","article-title":"Mutant SOD1 inhibits ER-Golgi transport in amyotrophic lateral sclerosis","volume":"129","author":"Atkin","year":"2014","journal-title":"J\u00a0Neurochem"},{"issue":"12","key":"10.1016\/j.berh.2018.07.012_bib57","doi-asserted-by":"crossref","first-page":"e1006450","DOI":"10.1371\/journal.pgen.1006450","article-title":"A\u00a0bystander mechanism explains the specific phenotype of a broadly expressed misfolded protein","volume":"12","author":"Klabonski","year":"2016","journal-title":"PLoS Genet"},{"key":"10.1016\/j.berh.2018.07.012_bib58","doi-asserted-by":"crossref","first-page":"6665","DOI":"10.4049\/jimmunol.163.12.6665","article-title":"Misfolding of HLA-B27 as a result of its B pocket suggests a novel mechanism for its role in susceptibility to spondyloarthropathies","volume":"163","author":"Mear","year":"1999","journal-title":"J\u00a0Immunol"},{"key":"10.1016\/j.berh.2018.07.012_bib59","doi-asserted-by":"crossref","first-page":"1896","DOI":"10.1073\/pnas.94.5.1896","article-title":"Misfolded major histocompatibility complex class I heavy chains are translocated into the cytoplasm and degraded by the proteasome","volume":"94","author":"Hughes","year":"1997","journal-title":"Proc Natl Acad Sci USA"},{"issue":"5","key":"10.1016\/j.berh.2018.07.012_bib60","doi-asserted-by":"crossref","first-page":"2034","DOI":"10.1073\/pnas.1016229108","article-title":"HRD1 and UBE2J1 target misfolded MHC class I heavy chains for endoplasmic reticulum-associated degradation","volume":"108","author":"Burr","year":"2011","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"11","key":"10.1016\/j.berh.2018.07.012_bib61","doi-asserted-by":"crossref","first-page":"2976","DOI":"10.1002\/art.38809","article-title":"Endoplasmic reticulum degradation-enhancing alpha-mannosidase-like protein 1 targets misfolded HLA-B27 dimers for endoplasmic reticulum-associated degradation","volume":"66","author":"Guiliano","year":"2014","journal-title":"Arthritis Rheum"},{"issue":"9","key":"10.1016\/j.berh.2018.07.012_bib62","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1038\/ncb0910-814","article-title":"Eaten alive: a history of macroautophagy","volume":"12","author":"Yang","year":"2010","journal-title":"Nat Cell Biol"},{"issue":"6","key":"10.1016\/j.berh.2018.07.012_bib63","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1038\/ncb2979","article-title":"Cargo recognition and trafficking in selective autophagy","volume":"16","author":"Stolz","year":"2014","journal-title":"Nat Cell Biol"},{"issue":"2","key":"10.1016\/j.berh.2018.07.012_bib64","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/j.molcel.2010.09.023","article-title":"Autophagy and the integrated stress response","volume":"40","author":"Kroemer","year":"2010","journal-title":"Mol Cell"},{"issue":"9","key":"10.1016\/j.berh.2018.07.012_bib65","doi-asserted-by":"crossref","first-page":"5045","DOI":"10.4049\/jimmunol.162.9.5045","article-title":"Cutting edge: HLA-B27 can form a novel beta 2-microglobulin-free heavy chain homodimer structure","volume":"162","author":"Allen","year":"1999","journal-title":"J\u00a0Immunol"},{"issue":"4","key":"10.1016\/j.berh.2018.07.012_bib66","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1002\/eji.201445307","article-title":"F\u00a0pocket flexibility influences the tapasin dependence of two differentially disease-associated MHC Class I proteins","volume":"45","author":"Abualrous","year":"2015","journal-title":"Eur J Immunol"},{"issue":"2","key":"10.1016\/j.berh.2018.07.012_bib67","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1084\/jem.20031690","article-title":"Dual, HLA-B27 subtype-dependent conformation of a self-peptide","volume":"199","author":"Hulsmeyer","year":"2004","journal-title":"J\u00a0Exp Med"},{"key":"10.1016\/j.berh.2018.07.012_bib68","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1002\/art.39567","article-title":"Increased conformational flexibility characterizes HLA-B*27 subtypes associated with ankylosing spondylitis","volume":"68","author":"Loll","year":"2016","journal-title":"Arthritis Rheum"},{"issue":"5","key":"10.1016\/j.berh.2018.07.012_bib69","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1002\/art.39566","article-title":"Editorial: HLA-B27: the story continues to unfold","volume":"68","author":"Powis","year":"2016","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.berh.2018.07.012_bib70","doi-asserted-by":"crossref","first-page":"1534","DOI":"10.1073\/pnas.91.4.1534","article-title":"A\u00a0subset of HLA-B27 molecules contains peptides much longer than nonamers","volume":"91","author":"Urban","year":"1994","journal-title":"Proc Natl Acad Sci USA"},{"issue":"4","key":"10.1016\/j.berh.2018.07.012_bib71","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1136\/annrheumdis-2011-200347","article-title":"Endoplasmic reticulum aminopeptidase 1 (ERAP1) exhibits functionally significant interaction with HLA-B27 and relates to subtype specificity in ankylosing spondylitis","volume":"71","author":"Haroon","year":"2012","journal-title":"Ann Rheum Dis"},{"issue":"2","key":"10.1016\/j.berh.2018.07.012_bib72","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1002\/art.38249","article-title":"Critical role of endoplasmic reticulum aminopeptidase 1 in determining the length and sequence of peptides bound and presented by HLA-B27","volume":"66","author":"Chen","year":"2014","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.berh.2018.07.012_bib73","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.molimm.2016.04.002","article-title":"ERAP1 reduces accumulation of aberrant and disulfide-linked forms of HLA-B27 on the cell surface","volume":"74","author":"Tran","year":"2016","journal-title":"Mol Immunol"},{"issue":"3","key":"10.1016\/j.berh.2018.07.012_bib74","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1002\/art.38963","article-title":"Revisiting the arthritogenic peptide theory: quantitative not qualitative changes in the peptide repertoire of HLA-B27 allotypes","volume":"67","author":"Schittenhelm","year":"2015","journal-title":"Arthritis Rheum"},{"issue":"6","key":"10.1016\/j.berh.2018.07.012_bib75","doi-asserted-by":"crossref","first-page":"1867","DOI":"10.1074\/mcp.M115.056358","article-title":"Human leukocyte antigen (HLA) B27 allotype-specific binding and candidate arthritogenic peptides revealed through heuristic clustering of data-independent acquisition mass spectrometry (DIA-MS) data","volume":"15","author":"Schittenhelm","year":"2016","journal-title":"Mol Cell Proteomics"},{"issue":"7","key":"10.1016\/j.berh.2018.07.012_bib76","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1038\/nm.2817","article-title":"IL-23 induces spondyloarthropathy by acting on ROR-gammat+ CD3+CD4-CD8- entheseal resident T cells","volume":"18","author":"Sherlock","year":"2012","journal-title":"Nat Med"},{"issue":"7","key":"10.1016\/j.berh.2018.07.012_bib77","doi-asserted-by":"crossref","first-page":"2211","DOI":"10.1002\/art.34423","article-title":"beta-glucan triggers spondylarthritis and Crohn's disease-like ileitis in SKG mice","volume":"64","author":"Ruutu","year":"2012","journal-title":"Arthritis Rheum"},{"issue":"9","key":"10.1016\/j.berh.2018.07.012_bib78","doi-asserted-by":"crossref","first-page":"1816","DOI":"10.1002\/art.40150","article-title":"Brief report: group 3 innate lymphoid cells in human enthesis","volume":"69","author":"Cuthbert","year":"2017","journal-title":"Arthritis Rheum"},{"issue":"4","key":"10.1016\/j.berh.2018.07.012_bib79","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1002\/art.40028","article-title":"Discovery of T Cell receptor beta motifs specific to HLA-B27-Positive ankylosing spondylitis by deep repertoire sequence analysis","volume":"69","author":"Faham","year":"2017","journal-title":"Arthritis Rheum"},{"issue":"11","key":"10.1016\/j.berh.2018.07.012_bib80","doi-asserted-by":"crossref","first-page":"3586","DOI":"10.1002\/art.21395","article-title":"Expansion and enhanced survival of natural killer cells expressing the killer immunoglobulin-like receptor KIR3DL2 in spondylarthritis","volume":"52","author":"Chan","year":"2005","journal-title":"Arthritis Rheum"},{"issue":"7","key":"10.1016\/j.berh.2018.07.012_bib81","doi-asserted-by":"crossref","first-page":"3216","DOI":"10.4049\/jimmunol.1202926","article-title":"KIR3DL2 binds to HLA-B27 dimers and free H chains more strongly than other HLA class I and promotes the expansion of T cells in ankylosing spondylitis","volume":"190","author":"Wong-Baeza","year":"2013","journal-title":"J\u00a0Immunol"},{"issue":"4","key":"10.1016\/j.berh.2018.07.012_bib82","doi-asserted-by":"crossref","first-page":"2672","DOI":"10.4049\/jimmunol.1002653","article-title":"Th17 cells expressing KIR3DL2+ and responsive to HLA-B27 homodimers are increased in ankylosing spondylitis","volume":"186","author":"Bowness","year":"2011","journal-title":"J\u00a0Immunol"},{"key":"10.1016\/j.berh.2018.07.012_bib83","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1002\/art.39515","article-title":"Activation-induced KIR3DL2 binding to HLA-B27 licenses pathogenic T cell differentiation in Spondyloarthritis","volume":"68","author":"Ridley","year":"2015","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.berh.2018.07.012_bib84","doi-asserted-by":"crossref","first-page":"2299","DOI":"10.4049\/jimmunol.137.7.2299","article-title":"Monoclonal antibodies raised against denatured HLA-B locus H-chains permit biochemical characterization of certain HLA-C locus products","volume":"137","author":"Stam","year":"1986","journal-title":"J\u00a0Immunol"},{"issue":"4","key":"10.1016\/j.berh.2018.07.012_bib85","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1136\/annrheumdis-2012-203080","article-title":"Expression of aberrant HLA-B27 molecules is dependent on B27 dosage and peptide supply","volume":"73","author":"McHugh","year":"2014","journal-title":"Ann Rheum Dis"},{"issue":"5","key":"10.1016\/j.berh.2018.07.012_bib86","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1002\/eji.200737882","article-title":"Endoplasmic reticulum stress and the unfolded protein response are linked to synergistic IFN-beta induction via X-box binding protein 1","volume":"38","author":"Smith","year":"2008","journal-title":"Eur J Immunol"},{"issue":"5","key":"10.1016\/j.berh.2018.07.012_bib87","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1038\/ni.1857","article-title":"TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages","volume":"11","author":"Martinon","year":"2010","journal-title":"Nat Immunol"},{"key":"10.1016\/j.berh.2018.07.012_bib88","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1146\/annurev-immunol-032414-112116","article-title":"Endoplasmic reticulum stress in immunity","volume":"33","author":"Bettigole","year":"2015","journal-title":"Annu Rev Immunol"},{"issue":"9","key":"10.1016\/j.berh.2018.07.012_bib89","doi-asserted-by":"crossref","first-page":"2633","DOI":"10.1002\/art.24763","article-title":"HLA-B27 misfolding and the unfolded protein response augment interleukin-23 production and are associated with Th17 activation in transgenic rats","volume":"60","author":"DeLay","year":"2009","journal-title":"Arthritis Rheum"},{"issue":"41","key":"10.1016\/j.berh.2018.07.012_bib90","doi-asserted-by":"crossref","first-page":"17698","DOI":"10.1073\/pnas.1011736107","article-title":"Endoplasmic reticulum stress-induced transcription factor, CHOP, is crucial for dendritic cell IL-23 expression","volume":"107","author":"Goodall","year":"2010","journal-title":"Proc Natl Acad Sci USA"},{"issue":"8","key":"10.1016\/j.berh.2018.07.012_bib91","doi-asserted-by":"crossref","first-page":"2123","DOI":"10.1002\/art.38001","article-title":"HLA-B27 alters the response to tumor necrosis factor alpha and promotes osteoclastogenesis in bone marrow monocytes from HLA-B27-transgenic rats","volume":"65","author":"Layh-Schmitt","year":"2013","journal-title":"Arthritis Rheum"},{"issue":"3","key":"10.1016\/j.berh.2018.07.012_bib92","doi-asserted-by":"crossref","first-page":"574","DOI":"10.3899\/jrheum.101257","article-title":"Interferon-gamma contributes to HLA-B27-associated unfolded protein response in spondyloarthropathies","volume":"39","author":"Feng","year":"2012","journal-title":"J\u00a0Rheumatol"},{"key":"10.1016\/j.berh.2018.07.012_bib93","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/03009740802213310","article-title":"Upregulation of 78-kDa glucose-regulated protein in macrophages in peripheral joints of active ankylosing spondylitis","volume":"37","author":"Dong","year":"2008","journal-title":"Scand J Rheumatol"},{"issue":"1","key":"10.1016\/j.berh.2018.07.012_bib94","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1093\/rheumatology\/kev245","article-title":"Ankylosing spondylitis patients display altered dendritic cell and T cell populations that implicate pathogenic roles for the IL-23 cytokine axis and intestinal inflammation","volume":"55","author":"Wright","year":"2016","journal-title":"Rheumatology (Oxford)"},{"issue":"6","key":"10.1016\/j.berh.2018.07.012_bib95","doi-asserted-by":"crossref","first-page":"1640","DOI":"10.1002\/art.23512","article-title":"Gene expression analysis of macrophages derived from ankylosing spondylitis patients reveals interferon-gamma dysregulation","volume":"58","author":"Smith","year":"2008","journal-title":"Arthritis Rheum"},{"issue":"12","key":"10.1016\/j.berh.2018.07.012_bib96","doi-asserted-by":"crossref","first-page":"3807","DOI":"10.1002\/art.30593","article-title":"Ankylosing spondylitis macrophage production of higher levels of interleukin-23 in response to lipopolysaccharide without induction of a significant unfolded protein response","volume":"63","author":"Zeng","year":"2011","journal-title":"Arthritis Rheum"},{"issue":"3","key":"10.1016\/j.berh.2018.07.012_bib97","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1136\/annrheumdis-2013-204170","article-title":"No evidence for a critical role of the unfolded protein response in synovium and blood of patients with ankylosing spondylitis","volume":"73","author":"Neerinckx","year":"2014","journal-title":"Ann Rheum Dis"},{"issue":"6885","key":"10.1016\/j.berh.2018.07.012_bib98","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1038\/417177a","article-title":"Transient aggregation of ubiquitinated proteins during dendritic cell maturation","volume":"417","author":"Lelouard","year":"2002","journal-title":"Nature"},{"issue":"12","key":"10.1016\/j.berh.2018.07.012_bib99","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1038\/nrd2755","article-title":"Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities","volume":"7","author":"Kim","year":"2008","journal-title":"Nat Rev Drug Discov"},{"issue":"11","key":"10.1016\/j.berh.2018.07.012_bib100","doi-asserted-by":"crossref","first-page":"3425","DOI":"10.1002\/art.24023","article-title":"Correlation between dendritic cell functional defect and spondylarthritis phenotypes in HLA-B27\/HUMAN beta2-microglobulin-transgenic rat lines","volume":"58","author":"Fert","year":"2008","journal-title":"Arthritis Rheum"},{"issue":"9","key":"10.1016\/j.berh.2018.07.012_bib101","doi-asserted-by":"crossref","first-page":"2622","DOI":"10.1002\/art.24780","article-title":"Dendritic cells from spondylarthritis-prone HLA-B27-transgenic rats display altered cytoskeletal dynamics, class II major histocompatibility complex expression, and viability","volume":"60","author":"Dhaenens","year":"2009","journal-title":"Arthritis Rheum"},{"issue":"10","key":"10.1016\/j.berh.2018.07.012_bib102","doi-asserted-by":"crossref","first-page":"3199","DOI":"10.1002\/art.34561","article-title":"Expression of HLA-B27 causes loss of migratory dendritic cells in a rat model of spondylarthritis","volume":"64","author":"Utriainen","year":"2012","journal-title":"Arthritis Rheum"},{"issue":"5","key":"10.1016\/j.berh.2018.07.012_bib103","doi-asserted-by":"crossref","first-page":"1478","DOI":"10.1002\/art.22572","article-title":"Alteration of antigen-independent immunologic synapse formation between dendritic cells from HLA-B27-transgenic rats and CD4+ T cells: selective impairment of costimulatory molecule engagement by mature HLA-B27","volume":"56","author":"Hacquard-Bouder","year":"2007","journal-title":"Arthritis Rheum"},{"issue":"9","key":"10.1016\/j.berh.2018.07.012_bib104","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1016\/j.it.2011.06.003","article-title":"Intestinal CD103+ dendritic cells: master regulators of tolerance?","volume":"32","author":"Scott","year":"2011","journal-title":"Trends Immunol"},{"issue":"8","key":"10.1016\/j.berh.2018.07.012_bib105","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1084\/jem.20051100","article-title":"Functional specialization of gut CD103+ dendritic cells in the regulation of tissue-selective T cell homing","volume":"202","author":"Johansson-Lindbom","year":"2005","journal-title":"J\u00a0Exp Med"},{"issue":"8","key":"10.1016\/j.berh.2018.07.012_bib106","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1084\/jem.20040662","article-title":"Essential role for CD103 in the T cell-mediated regulation of experimental colitis","volume":"202","author":"Annacker","year":"2005","journal-title":"J\u00a0Exp Med"},{"issue":"1","key":"10.1016\/j.berh.2018.07.012_bib107","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1002\/art.33321","article-title":"Proinflammatory Th17 cells are expanded and induced by dendritic cells in spondylarthritis-prone HLA-B27-transgenic rats","volume":"64","author":"Glatigny","year":"2012","journal-title":"Arthritis Rheum"},{"issue":"1","key":"10.1016\/j.berh.2018.07.012_bib108","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.immuni.2012.09.020","article-title":"Distribution and compartmentalization of human circulating and tissue-resident memory T cell subsets","volume":"38","author":"Sathaliyawala","year":"2013","journal-title":"Immunity"},{"issue":"8","key":"10.1016\/j.berh.2018.07.012_bib109","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1038\/ng.873","article-title":"Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility","volume":"43","author":"Evans","year":"2011","journal-title":"Nat Genet"},{"key":"10.1016\/j.berh.2018.07.012_bib110","doi-asserted-by":"crossref","first-page":"7146","DOI":"10.1038\/ncomms8146","article-title":"Major histocompatibility complex associations of ankylosing spondylitis are complex and involve further epistasis with ERAP1","volume":"6","author":"Cortes","year":"2015","journal-title":"Nat Commun"},{"issue":"4","key":"10.1016\/j.berh.2018.07.012_bib111","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1097\/BOR.0000000000000188","article-title":"Endoplasmic reticulum aminopeptidase 1 and rheumatic disease: functional variation","volume":"27","author":"Tran","year":"2015","journal-title":"Curr Opin Rheumatol"},{"issue":"6","key":"10.1016\/j.berh.2018.07.012_bib112","doi-asserted-by":"crossref","first-page":"1525","DOI":"10.1002\/art.39072","article-title":"ERAP1 gene expression is influenced by nonsynonymous polymorphisms associated with predisposition to spondyloarthritis","volume":"67","author":"Costantino","year":"2015","journal-title":"Arthritis Rheum"},{"issue":"7","key":"10.1016\/j.berh.2018.07.012_bib113","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1038\/ni1208","article-title":"Concerted peptide trimming by human ERAP1 and ERAP2 aminopeptidase complexes in the endoplasmic reticulum","volume":"6","author":"Saveanu","year":"2005","journal-title":"Nat Immunol"},{"issue":"1","key":"10.1016\/j.berh.2018.07.012_bib114","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1038\/ni1286","article-title":"The aminopeptidase ERAAP shapes the peptide repertoire displayed by major histocompatibility complex class I molecules","volume":"7","author":"Hammer","year":"2006","journal-title":"Nat Immunol"},{"issue":"6","key":"10.1016\/j.berh.2018.07.012_bib115","doi-asserted-by":"crossref","first-page":"3033","DOI":"10.4049\/jimmunol.0903712","article-title":"Endoplasmic reticulum aminopeptidase associated with antigen processing defines the composition and structure of MHC class I peptide repertoire in normal and virus-infected cells","volume":"184","author":"Blanchard","year":"2010","journal-title":"J\u00a0Immunol"},{"issue":"12","key":"10.1016\/j.berh.2018.07.012_bib116","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1038\/ni860","article-title":"The ER aminopeptidase ERAP1 enhances or limits antigen presentation by trimming epitopes to 8-9 residues","volume":"3","author":"York","year":"2002","journal-title":"Nat Immunol"},{"issue":"24","key":"10.1016\/j.berh.2018.07.012_bib117","doi-asserted-by":"crossref","first-page":"9202","DOI":"10.1073\/pnas.0603095103","article-title":"Endoplasmic reticulum aminopeptidase 1 (ERAP1) trims MHC class I-presented peptides in\u00a0vivo and plays an important role in immunodominance","volume":"103","author":"York","year":"2006","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.berh.2018.07.012_bib118","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1136\/annrheumdis-2014-206996","article-title":"Silencing or inhibition of endoplasmic reticulum aminopeptidase 1 (ERAP1) suppresses free heavy chain expression and Th17 responses in ankylosing spondylitis","volume":"75","author":"Chen","year":"2016","journal-title":"Ann Rheum Dis"},{"issue":"8","key":"10.1016\/j.berh.2018.07.012_bib119","doi-asserted-by":"crossref","first-page":"497","DOI":"10.3109\/08916934.2013.819855","article-title":"Endoplasmic reticulum aminopeptidase-1 alleles associated with increased risk of ankylosing spondylitis reduce HLA-B27 mediated presentation of multiple antigens","volume":"46","author":"Seregin","year":"2013","journal-title":"Autoimmunity"},{"issue":"49","key":"10.1016\/j.berh.2018.07.012_bib120","doi-asserted-by":"crossref","first-page":"19890","DOI":"10.1073\/pnas.1309781110","article-title":"Rationally designed inhibitor targeting antigen-trimming aminopeptidases enhances antigen presentation and cytotoxic T-cell responses","volume":"110","author":"Zervoudi","year":"2013","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"12","key":"10.1016\/j.berh.2018.07.012_bib121","doi-asserted-by":"crossref","first-page":"5520","DOI":"10.4049\/jimmunol.1400343","article-title":"HLA-B27, but not HLA-B7, immunodominance to influenza is ERAP dependent","volume":"192","author":"Akram","year":"2014","journal-title":"J\u00a0Immunol"},{"issue":"4","key":"10.1016\/j.berh.2018.07.012_bib122","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1074\/mcp.M116.066241","article-title":"The human leukocyte antigen (HLA)-B27 peptidome in\u00a0vivo, in spondyloarthritis-susceptible HLA-B27 transgenic rats and the effect of Erap1 deletion","volume":"16","author":"Barnea","year":"2017","journal-title":"Mol Cell Proteomics"},{"issue":"3","key":"10.1016\/j.berh.2018.07.012_bib123","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1152\/physrev.00045.2009","article-title":"Gut microbiota in health and disease","volume":"90","author":"Sekirov","year":"2010","journal-title":"Physiol Rev"},{"key":"10.1016\/j.berh.2018.07.012_bib124","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1146\/annurev-genom-090711-163814","article-title":"The human microbiome: our second genome","volume":"13","author":"Grice","year":"2012","journal-title":"Annu Rev Genom Hum Genet"},{"issue":"3","key":"10.1016\/j.berh.2018.07.012_bib125","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/j.berh.2011.01.018","article-title":"Reactive arthritis","volume":"25","author":"Hannu","year":"2011","journal-title":"Best Pract Res Clin Rheumatol"},{"key":"10.1016\/j.berh.2018.07.012_bib126","doi-asserted-by":"crossref","first-page":"2359","DOI":"10.1084\/jem.180.6.2359","article-title":"The germfree state prevents development of gut and joint inflammatory disease in HLA-B27 transgenic rats","volume":"180","author":"Taurog","year":"1994","journal-title":"J\u00a0Exp Med"},{"key":"10.1016\/j.berh.2018.07.012_bib127","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1172\/JCI118878","article-title":"Normal luminal bacteria, especially bacteroides species, mediate chronic colitis, gastritis, and arthritis in HLA-B27\/human b2 microglobulin transgenic rats","volume":"98","author":"Rath","year":"1996","journal-title":"J\u00a0Clin Invest"},{"issue":"6","key":"10.1016\/j.berh.2018.07.012_bib128","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1007\/s10067-006-0488-7","article-title":"Ankylosing spondylitis is linked to Klebsiella--the evidence","volume":"26","author":"Rashid","year":"2007","journal-title":"Clin Rheumatol"},{"key":"10.1016\/j.berh.2018.07.012_bib129","doi-asserted-by":"crossref","first-page":"872632","DOI":"10.1155\/2013\/872632","article-title":"The link between ankylosing spondylitis, Crohn's disease, Klebsiella, and starch consumption","volume":"2013","author":"Rashid","year":"2013","journal-title":"Clin Dev Immunol"},{"key":"10.1016\/j.berh.2018.07.012_bib130","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.micpath.2018.02.020","article-title":"The association of HLA-B27 and Klebsiella pneumoniae in ankylosing spondylitis: a systematic review","volume":"117","author":"Zhang","year":"2018","journal-title":"Microb Pathog"},{"key":"10.1016\/j.berh.2018.07.012_bib131","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1016\/0140-6736(93)91760-J","article-title":"HLA-B27-restricted CD8 T cells from synovial fluids of patients with reactive arthritis and ankylosing spondylitis","volume":"342","author":"Hermann","year":"1993","journal-title":"Lancet"},{"key":"10.1016\/j.berh.2018.07.012_bib132","doi-asserted-by":"crossref","first-page":"3554","DOI":"10.4049\/jimmunol.148.11.3554","article-title":"HLA-B27 expression modulates gram-negative bacterial invasion into transfected target cells","volume":"148","author":"Kapasi","year":"1992","journal-title":"J\u00a0Immunol"},{"issue":"10","key":"10.1016\/j.berh.2018.07.012_bib133","doi-asserted-by":"crossref","first-page":"4236","DOI":"10.1128\/IAI.65.10.4236-4242.1997","article-title":"HLA-B27 modulates the survival of Salmonella enteritidis in transfected L cells, possibly by impaired nitric oxide production","volume":"65","author":"Virtala","year":"1997","journal-title":"Infect Immun"},{"issue":"7","key":"10.1016\/j.berh.2018.07.012_bib134","doi-asserted-by":"crossref","first-page":"2255","DOI":"10.1002\/art.20336","article-title":"Enhanced intracellular replication of Salmonella enteritidis in HLA-B27-expressing human monocytic cells: dependency on glutamic acid at position 45 in the B pocket of HLA-B27","volume":"50","author":"Penttinen","year":"2004","journal-title":"Arthritis Rheum"},{"issue":"8","key":"10.1016\/j.berh.2018.07.012_bib135","doi-asserted-by":"crossref","first-page":"2652","DOI":"10.1002\/art.22746","article-title":"Evidence that the p38 MAP kinase pathway is dysregulated in HLA-B27-expressing human monocytic cells: correlation with HLA-B27 misfolding","volume":"56","author":"Sahlberg","year":"2007","journal-title":"Arthritis Rheum"},{"issue":"3","key":"10.1016\/j.berh.2018.07.012_bib136","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1002\/art.33391","article-title":"Enhanced phosphorylation of STAT-1 is dependent on double-stranded RNA-dependent protein kinase signaling in HLA-B27-expressing U937 monocytic cells","volume":"64","author":"Ruuska","year":"2012","journal-title":"Arthritis Rheum"},{"issue":"2","key":"10.1016\/j.berh.2018.07.012_bib137","first-page":"180","article-title":"The causes of intestinal dysbiosis: a review","volume":"9","author":"Hawrelak","year":"2004","journal-title":"Alternative Med Rev"},{"issue":"4","key":"10.1016\/j.berh.2018.07.012_bib138","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1016\/j.immuni.2017.04.008","article-title":"Homeostatic immunity and the microbiota","volume":"46","author":"Belkaid","year":"2017","journal-title":"Immunity"},{"issue":"7484","key":"10.1016\/j.berh.2018.07.012_bib139","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1038\/nature12820","article-title":"Diet rapidly and reproducibly alters the human gut microbiome","volume":"505","author":"David","year":"2014","journal-title":"Nature"},{"issue":"7","key":"10.1016\/j.berh.2018.07.012_bib140","doi-asserted-by":"crossref","first-page":"R89","DOI":"10.1186\/gb-2014-15-7-r89","article-title":"Host lifestyle affects human microbiota on daily timescales","volume":"15","author":"David","year":"2014","journal-title":"Genome Biol"},{"issue":"8","key":"10.1016\/j.berh.2018.07.012_bib141","doi-asserted-by":"crossref","first-page":"e105684","DOI":"10.1371\/journal.pone.0105684","article-title":"HLA-B27 and human beta2-microglobulin affect the gut microbiota of transgenic rats","volume":"9","author":"Lin","year":"2014","journal-title":"PLoS One"},{"issue":"4","key":"10.1016\/j.berh.2018.07.012_bib142","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1002\/art.21740","article-title":"Additional human beta(2)-microglobulin curbs HLA-B27 misfolding and promotes arthritis and spondylitis without colitis in male HLA-B27-transgenic rats","volume":"54","author":"Tran","year":"2006","journal-title":"Arthritis Rheum"},{"issue":"9","key":"10.1016\/j.berh.2018.07.012_bib143","doi-asserted-by":"crossref","first-page":"2151","DOI":"10.1002\/art.39681","article-title":"Perturbed mucosal immunity and dysbiosis accompany clinical disease in a rat model of spondyloarthritis","volume":"68","author":"Asquith","year":"2016","journal-title":"Arthritis Rheum"},{"issue":"4","key":"10.1016\/j.berh.2018.07.012_bib144","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1002\/art.40405","article-title":"Effects of HLA-B27 on gut microbiota in experimental spondyloarthritis implicate an ecological model of dysbiosis","volume":"70","author":"Gill","year":"2018","journal-title":"Arthritis Rheum"},{"issue":"10","key":"10.1016\/j.berh.2018.07.012_bib145","doi-asserted-by":"crossref","first-page":"1984","DOI":"10.1002\/art.40183","article-title":"Intestinal metabolites are profoundly altered in the context of HLA-B27 expression and functionally modulate disease in a rat model of spondyloarthritis","volume":"69","author":"Asquith","year":"2017","journal-title":"Arthritis Rheum"},{"issue":"2","key":"10.1016\/j.berh.2018.07.012_bib146","first-page":"390","article-title":"International League of Associations for Rheumatology classification of juvenile idiopathic arthritis: second revision, Edmonton, 2001","volume":"31","author":"Petty","year":"2004","journal-title":"J\u00a0Rheumatol"},{"issue":"6","key":"10.1016\/j.berh.2018.07.012_bib147","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1136\/ard.2009.108233","article-title":"The development of Assessment of SpondyloArthritis international Society classification criteria for axial spondyloarthritis (part II): validation and final selection","volume":"68","author":"Rudwaleit","year":"2009","journal-title":"Ann Rheum Dis"}],"container-title":["Best Practice &amp; Research Clinical Rheumatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1521694218300378?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1521694218300378?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,7,9]],"date-time":"2024-07-09T13:57:18Z","timestamp":1720533438000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1521694218300378"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12]]},"references-count":147,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2017,12]]}},"alternative-id":["S1521694218300378"],"URL":"https:\/\/doi.org\/10.1016\/j.berh.2018.07.012","relation":{},"ISSN":["1521-6942"],"issn-type":[{"value":"1521-6942","type":"print"}],"subject":[],"published":{"date-parts":[[2017,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The role of HLA-B*27 in spondyloarthritis","name":"articletitle","label":"Article Title"},{"value":"Best Practice & Research Clinical Rheumatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.berh.2018.07.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}