{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T21:26:18Z","timestamp":1792531578872,"version":"4.5.0"},"reference-count":85,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,9,23]],"date-time":"2022-09-23T00:00:00Z","timestamp":1663891200000},"content-version":"am","delay-in-days":387,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Best Practice &amp; Research Clinical Rheumatology"],"published-print":{"date-parts":[[2021,9]]},"DOI":"10.1016\/j.berh.2021.101688","type":"journal-article","created":{"date-parts":[[2021,4,22]],"date-time":"2021-04-22T15:55:16Z","timestamp":1619106916000},"page":"101688","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"title":["Review for best practice in clinical rheumatology juvenile systemic sclerosis \u2013 Updates and practice points"],"prefix":"10.1016","volume":"35","author":[{"given":"Ivan","family":"Foeldvari","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathryn S.","family":"Torok","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.berh.2021.101688_bib1","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1093\/rheumatology\/39.5.556","article-title":"Favourable outcome in 135 children with juvenile systemic sclerosis: results of a multi-national survey","volume":"39","author":"Foeldvari","year":"2000","journal-title":"Rheumatology"},{"issue":"12","key":"10.1016\/j.berh.2021.101688_bib2","doi-asserted-by":"crossref","first-page":"3971","DOI":"10.1002\/art.22207","article-title":"Systemic sclerosis in childhood: clinical and immunologic features of 153 patients in an international database","volume":"54","author":"Martini","year":"2006","journal-title":"Arthritis Rheum"},{"issue":"1\u201313","key":"10.1016\/j.berh.2021.101688_bib3","article-title":"Characteristics OF the first 80 patients at timepoint OF first assessment included IN the juvenile systemic sclerosis inception cohort","volume":"4","author":"Foeldvari","year":"2018","journal-title":"J\u00a0Scleroderma and Related Disorders"},{"key":"10.1016\/j.berh.2021.101688_bib4","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1093\/rheumatology\/ken388","article-title":"Factors affecting survival in juvenile systemic sclerosis","volume":"48","author":"Martini","year":"2008","journal-title":"Rheumatology (Oxford)"},{"issue":"2","key":"10.1016\/j.berh.2021.101688_bib5","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1002\/acr.20070","article-title":"Incidence of childhood linear scleroderma and systemic sclerosis in the UK and Ireland","volume":"62","author":"Herrick","year":"2010","journal-title":"Arthritis Care Res"},{"issue":"2","key":"10.1016\/j.berh.2021.101688_bib6","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1177\/2397198318763701","article-title":"Assessing the prevalence of juvenile systemic sclerosis in childhood using administrative claims data from the United States","volume":"3","author":"Beukelman","year":"2018","journal-title":"Journal of Scleroderma and Related Disorders"},{"issue":"5","key":"10.1016\/j.berh.2021.101688_bib7","first-page":"1004","article-title":"Childhood onset systemic sclerosis: classification, clinical and serologic features, and survival in comparison with adult onset disease","volume":"33","author":"Scalapino","year":"2006","journal-title":"J\u00a0Rheumatol"},{"issue":"12","key":"10.1016\/j.berh.2021.101688_bib8","doi-asserted-by":"crossref","first-page":"1806","DOI":"10.1002\/acr.23547","article-title":"Clinical characteristics and factors associated with disability and impaired quality of life in children with juvenile systemic sclerosis: results from the childhood arthritis and rheumatology research alliance legacy registry","volume":"70","author":"Stevens","year":"2018","journal-title":"Arthritis Care Res"},{"issue":"2","key":"10.1016\/j.berh.2021.101688_bib9","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1002\/art.22551","article-title":"The pediatric rheumatology European society\/American college of rheumatology\/European league against rheumatism provisional classification criteria for juvenile systemic sclerosis","volume":"57","author":"Zulian","year":"2007","journal-title":"Arthritis Rheum"},{"issue":"No.5","key":"10.1016\/j.berh.2021.101688_bib10","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1002\/art.1780230510","article-title":"Preliminary criteria for the classification of systemic sclerosis ( scleroderma )","volume":"23","author":"Masi","year":"1980","journal-title":"Arthritis Rheum"},{"issue":"11","key":"10.1016\/j.berh.2021.101688_bib11","doi-asserted-by":"crossref","first-page":"1747","DOI":"10.1136\/annrheumdis-2013-204424","article-title":"Classification criteria for systemic sclerosis: an American college of rheumatology\/European league against rheumatism collaborative initiative","volume":"72","author":"van den Hoogen","year":"2013","journal-title":"Ann Rheum Dis"},{"issue":"4","key":"10.1016\/j.berh.2021.101688_bib12","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1016\/j.berh.2018.02.004","article-title":"Scleroderma in children","volume":"31","author":"Zulian","year":"2017","journal-title":"Best Pract Res Clin Rheumatol"},{"issue":"7","key":"10.1016\/j.berh.2021.101688_bib13","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1093\/rheumatology\/ker521","article-title":"Access to care for children and young people diagnosed with localized scleroderma or juvenile SSc in the UK","volume":"51","author":"Hawley","year":"2012","journal-title":"Rheumatology"},{"issue":"12","key":"10.1016\/j.berh.2021.101688_bib14","doi-asserted-by":"crossref","first-page":"3518","DOI":"10.1002\/art.11340","article-title":"Occurrence of Raynaud's phenomenon in children ages 12-15 years: prevalence and association with other common symptoms","volume":"48","author":"Jones","year":"2003","journal-title":"Arthritis Rheum"},{"issue":"5","key":"10.1016\/j.berh.2021.101688_bib15","first-page":"200","article-title":"Raynaud's syndrome in children: systematic review and development of recommendations for assessment and monitoring","volume":"34","author":"Pain","year":"2016","journal-title":"Clin Exp Rheumatol"},{"issue":"12","key":"10.1016\/j.berh.2021.101688_bib16","doi-asserted-by":"crossref","first-page":"3902","DOI":"10.1002\/art.24038","article-title":"Autoantibodies and microvascular damage are independent predictive factors for the progression of Raynaud's phenomenon to systemic sclerosis: a twenty-year prospective study of 586 patients, with validation of proposed criteria for early systemic sclerosis","volume":"58","author":"Koenig","year":"2008","journal-title":"Arthritis Rheum"},{"issue":"3","key":"10.1016\/j.berh.2021.101688_bib17","doi-asserted-by":"crossref","first-page":"102458","DOI":"10.1016\/j.autrev.2020.102458","article-title":"Standardisation of nailfold capillaroscopy for the assessment of patients with Raynaud's phenomenon and systemic sclerosis","volume":"19","author":"Smith","year":"2020","journal-title":"Autoimmun Rev"},{"issue":"5","key":"10.1016\/j.berh.2021.101688_bib18","first-page":"193","article-title":"Nailfold videocapillaroscopy in healthy children and adolescents: description of normal patterns","volume":"34","author":"Piotto","year":"2016","journal-title":"Clin Exp Rheumatol"},{"issue":"5","key":"10.1016\/j.berh.2021.101688_bib19","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1111\/j.1525-1470.2006.00278.x","article-title":"The prognostic value of nailfold capillary changes for the development of connective tissue disease in children and adolescents with primary raynaud phenomenon: a follow-up study of 250 patients","volume":"23","author":"Pavlov-Dolijanovic","year":"2006","journal-title":"Pediatr Dermatol"},{"issue":"4 Pt 1","key":"10.1016\/j.berh.2021.101688_bib20","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1542\/peds.111.4.715","article-title":"Raynaud's phenomenon in children: a retrospective review of 123 patients","volume":"111","author":"Nigrovic","year":"2003","journal-title":"Pediatrics"},{"issue":"1","key":"10.1016\/j.berh.2021.101688_bib21","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1111\/j.1651-2227.1993.tb12539.x","article-title":"Progressive systemic sclerosis sine scleroderma in a child presenting as nocturnal seizures and Raynaud's phenomenon","volume":"82","author":"Navon","year":"1993","journal-title":"Acta Paediatr"},{"issue":"1","key":"10.1016\/j.berh.2021.101688_bib22","doi-asserted-by":"crossref","first-page":"11","DOI":"10.5301\/jsrd.5000231","article-title":"Standardization of the modified Rodnan skin score for use in clinical trials of systemic sclerosis","volume":"2","author":"Khanna","year":"2017","journal-title":"J\u00a0Scleroderma Relat Disord"},{"issue":"7","key":"10.1016\/j.berh.2021.101688_bib23","first-page":"1281","article-title":"Inter and intraobserver variability of total skin thickness score (modified Rodnan TSS) in systemic sclerosis","volume":"22","author":"Clements","year":"1995","journal-title":"J\u00a0Rheumatol"},{"issue":"1","key":"10.1016\/j.berh.2021.101688_bib24","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1136\/ard.2009.127621","article-title":"Skin thickness progression rate: a predictor of mortality and early internal organ involvement in diffuse scleroderma","volume":"70","author":"Domsic","year":"2011","journal-title":"Ann Rheum Dis"},{"issue":"1","key":"10.1016\/j.berh.2021.101688_bib25","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1093\/rheumatology\/kei106","article-title":"Healthy children have a significantly increased skin score assessed with the modified Rodnan skin score","volume":"45","author":"Foeldvari","year":"2006","journal-title":"Rheumatology"},{"key":"10.1016\/j.berh.2021.101688_bib26","article-title":"Under detection of interstitial lung disease in juvenile systemic sclerosis (jSSc)","author":"Foeldvari","year":"2020","journal-title":"Arthritis Care Res (Hoboken)"},{"issue":"127","key":"10.1016\/j.berh.2021.101688_bib27","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1183\/09059180.00005512","article-title":"Scleroderma lung disease","volume":"22","author":"Solomon","year":"2013","journal-title":"Eur Respir Rev"},{"issue":"9","key":"10.1016\/j.berh.2021.101688_bib28","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1053\/crad.2000.0490","article-title":"Computed tomography of diffuse interstitial lung disease in children","volume":"55","author":"Koh","year":"2000","journal-title":"Clin Radiol"},{"issue":"3","key":"10.1016\/j.berh.2021.101688_bib29","doi-asserted-by":"crossref","first-page":"691","DOI":"10.2214\/ajr.170.3.9490955","article-title":"Systemic sclerosis: using high-resolution CT to detect lung disease in children","volume":"170","author":"Seely","year":"1998","journal-title":"AJR Am J Roentgenol"},{"issue":"12","key":"10.1016\/j.berh.2021.101688_bib30","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1002\/ppul.21141","article-title":"HRCT and pulmonary function tests in monitoring of lung involvement in juvenile systemic sclerosis","volume":"44","author":"Panigada","year":"2009","journal-title":"Pediatr Pulmonol"},{"issue":"5","key":"10.1016\/j.berh.2021.101688_bib31","doi-asserted-by":"crossref","DOI":"10.1183\/13993003.02026-2019","article-title":"Predictors of progression in systemic sclerosis patients with interstitial lung disease","volume":"55","author":"Distler","year":"2020","journal-title":"Eur Respir J"},{"key":"10.1016\/j.berh.2021.101688_bib32","article-title":"Reproducibility of the six-minute walk test in children and youth with juvenile idiopathic arthritis","author":"Pritchard","year":"2020","journal-title":"Arthritis Care Res (Hoboken)"},{"issue":"6","key":"10.1016\/j.berh.2021.101688_bib33","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1136\/adc.2007.123653","article-title":"The 6-minute walk test: normal values for children of 4-11 years of age","volume":"93","author":"Lammers","year":"2008","journal-title":"Arch Dis Child"},{"issue":"6","key":"10.1016\/j.berh.2021.101688_bib34","doi-asserted-by":"crossref","first-page":"1324","DOI":"10.1183\/09031936.00080312","article-title":"Multi-ethnic reference values for spirometry for the 3-95-yr age range: the global lung function 2012 equations","volume":"40","author":"Quanjer","year":"2012","journal-title":"Eur Respir J"},{"issue":"12","key":"10.1016\/j.berh.2021.101688_bib35","doi-asserted-by":"crossref","first-page":"1304","DOI":"10.1164\/rccm.200605-642ST","article-title":"An official American Thoracic Society\/European Respiratory Society statement: pulmonary function testing in preschool children","volume":"175","author":"Beydon","year":"2007","journal-title":"Am J Respir Crit Care Med"},{"issue":"8","key":"10.1016\/j.berh.2021.101688_bib36","doi-asserted-by":"crossref","first-page":"e70","DOI":"10.1164\/rccm.201908-1590ST","article-title":"Standardization of spirometry 2019 update. An official American thoracic society and European respiratory society technical statement","volume":"200","author":"Graham","year":"2019","journal-title":"Am J Respir Crit Care Med"},{"issue":"11","key":"10.1016\/j.berh.2021.101688_bib37","doi-asserted-by":"crossref","first-page":"1892","DOI":"10.1002\/art.41415","article-title":"Performance characteristics of pulmonary function tests for the detection of interstitial lung disease in adults with early diffuse cutaneous systemic sclerosis","volume":"72","author":"Bernstein","year":"2020","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.berh.2021.101688_bib38","doi-asserted-by":"crossref","DOI":"10.1016\/S2213-2600(20)30318-0","article-title":"Tocilizumab in systemic sclerosis: a randomised, doubleblind, placebo-controlled, phase 3 trial","author":"Khanna","year":"2020","journal-title":"Lancet Respir Med"},{"issue":"26","key":"10.1016\/j.berh.2021.101688_bib39","doi-asserted-by":"crossref","first-page":"2518","DOI":"10.1056\/NEJMoa1903076","article-title":"Nintedanib for systemic sclerosis-associated interstitial lung disease","volume":"380","author":"Distler","year":"2019","journal-title":"N\u00a0Engl J Med"},{"issue":"8","key":"10.1016\/j.berh.2021.101688_bib40","doi-asserted-by":"crossref","first-page":"2024","DOI":"10.1093\/rheumatology\/kez571","article-title":"Lung ultrasound B-lines and serum KL-6 correlate with the severity of idiopathic inflammatory myositis-associated interstitial lung disease","volume":"59","author":"Wang","year":"2020","journal-title":"Rheumatology"},{"key":"10.1016\/j.berh.2021.101688_bib41","article-title":"Lung magnetic resonance imaging in systemic sclerosis: a new promising approach to evaluate pulmonary involvement and progression","author":"Gargani","year":"2020","journal-title":"Clin Rheumatol"},{"key":"10.1016\/j.berh.2021.101688_bib42","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1177\/2397198319889549","article-title":"Natural history of systemic sclerosis\u2013 related interstitial lung disease: how to identify a progressive fibrosing phenotype","volume":"5","author":"Volkmann","year":"2020","journal-title":"J\u00a0Scleroderma and Relat Disord"},{"issue":"2","key":"10.1016\/j.berh.2021.101688_bib43","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1136\/annrheumdis-2014-206076","article-title":"Relationship between quantitative radiographic assessments of interstitial lung disease and physiological and clinical features of systemic sclerosis","volume":"75","author":"Tashkin","year":"2016","journal-title":"Ann Rheum Dis"},{"issue":"3","key":"10.1016\/j.berh.2021.101688_bib44","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/j.rdc.2015.04.006","article-title":"Management of systemic-sclerosis-associated interstitial lung disease","volume":"41","author":"Silver","year":"2015","journal-title":"Rheum Dis Clin N Am"},{"issue":"4","key":"10.1016\/j.berh.2021.101688_bib45","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1002\/acr.21583","article-title":"Clinical decision rule to predict the presence of interstitial lung disease in systemic sclerosis","volume":"64","author":"Steele","year":"2012","journal-title":"Arthritis Care Res"},{"key":"10.1016\/j.berh.2021.101688_bib46","doi-asserted-by":"crossref","first-page":"1651","DOI":"10.1093\/rheumatology\/keaa584","article-title":"Consensus-based recommendations for the management of juvenile systemic sclerosis","volume":"60","author":"Foeldvari","year":"2021","journal-title":"Rheumatology (Oxford)"},{"issue":"6","key":"10.1016\/j.berh.2021.101688_bib47","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.1002\/art.38390","article-title":"Prediction of pulmonary complications and long-term survival in systemic sclerosis","volume":"66","author":"Nihtyanova","year":"2014","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.berh.2021.101688_bib48","doi-asserted-by":"crossref","first-page":"1444","DOI":"10.1002\/acr.23778","article-title":"Relationship between esophageal abnormalities on fluoroscopic esophagram and pulmonary function testing in juvenile systemic sclerosis","volume":"71","author":"Ambartsumyan","year":"2019","journal-title":"Arthritis Care Res"},{"issue":"3","key":"10.1016\/j.berh.2021.101688_bib49","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1007\/s40674-016-0050-y","article-title":"Autoantibodies and their role in scleroderma clinical care","volume":"2","author":"Domsic","year":"2016","journal-title":"Curr Treat Options in Rheumatol"},{"issue":"6","key":"10.1016\/j.berh.2021.101688_bib50","doi-asserted-by":"crossref","first-page":"1831","DOI":"10.1002\/art.24525","article-title":"The three-year incidence of pulmonary arterial hypertension associated with systemic sclerosis in a multicenter nationwide longitudinal study in France","volume":"60","author":"Hachulla","year":"2009","journal-title":"Arthritis Rheum"},{"issue":"4","key":"10.1016\/j.berh.2021.101688_bib51","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1093\/rheumatology\/keu350","article-title":"Assessment of myocardial fibrosis and microvascular damage in systemic sclerosis by magnetic resonance imaging and coronary angiotomography","volume":"54","author":"Rodriguez-Reyna","year":"2015","journal-title":"Rheumatology"},{"issue":"8","key":"10.1016\/j.berh.2021.101688_bib52","doi-asserted-by":"crossref","first-page":"1686","DOI":"10.1007\/s00246-017-1714-6","article-title":"New insights into cardiac involvement in juvenile scleroderma: a three-dimensional echocardiographic assessment unveils subclinical ventricle dysfunction","volume":"38","author":"Dedeoglu","year":"2017","journal-title":"Pediatr Cardiol"},{"issue":"6","key":"10.1016\/j.berh.2021.101688_bib53","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.1183\/09031936.00150414","article-title":"An official systematic review of the European Respiratory Society\/American Thoracic Society: measurement properties of field walking tests in chronic respiratory disease","volume":"44","author":"Singh","year":"2014","journal-title":"Eur Respir J"},{"issue":"3","key":"10.1016\/j.berh.2021.101688_bib54","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1002\/art.21175","article-title":"Physiologic response of the six-minute walk test in children with juvenile idiopathic arthritis","volume":"53","author":"Paap","year":"2005","journal-title":"Arthritis Rheum"},{"issue":"9","key":"10.1016\/j.berh.2021.101688_bib55","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.3899\/jrheum.170994","article-title":"Reproducibility and utility of the 6-minute walk test in systemic sclerosis","volume":"45","author":"Pugnet","year":"2018","journal-title":"J\u00a0Rheumatol"},{"issue":"2","key":"10.1016\/j.berh.2021.101688_bib56","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1007\/s00296-018-4185-z","article-title":"Evaluation of six-minute walk test in juvenile systemic sclerosis","volume":"39","author":"Koker","year":"2019","journal-title":"Rheumatol Int"},{"key":"10.1016\/j.berh.2021.101688_bib57","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.ejim.2018.10.013","article-title":"Cardiac troponin T and NT-proBNP as diagnostic and prognostic biomarkers of primary cardiac involvement and disease severity in systemic sclerosis: a prospective study","volume":"60","author":"Bosello","year":"2019","journal-title":"Eur J Intern Med"},{"issue":"13","key":"10.1016\/j.berh.2021.101688_bib58","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.2217\/bmm-2020-0232","article-title":"Current role of cardiac biomarkers in extra-cardiac diseases in children","volume":"14","author":"Rodriguez-Gonzalez","year":"2020","journal-title":"Biomarkers Med"},{"issue":"1","key":"10.1016\/j.berh.2021.101688_bib59","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/s00246-008-9258-4","article-title":"NT-pro-B-type natriuretic peptide in infants and children: reference values based on combined data from four studies","volume":"30","author":"Nir","year":"2009","journal-title":"Pediatr Cardiol"},{"key":"10.1016\/j.berh.2021.101688_bib60","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.jpeds.2020.01.001","article-title":"Serial measurements of N-terminal pro-B-type natriuretic peptide serum level for monitoring pulmonary arterial hypertension in children","volume":"220","author":"Said","year":"2020","journal-title":"J\u00a0Pediatr"},{"issue":"1","key":"10.1016\/j.berh.2021.101688_bib61","doi-asserted-by":"crossref","first-page":"191","DOI":"10.3899\/jrheum.080021","article-title":"Evaluation of heart rhythm variability and arrhythmia in children with systemic and localized scleroderma","volume":"36","author":"Wozniak","year":"2009","journal-title":"J\u00a0Rheumatol"},{"issue":"9","key":"10.1016\/j.berh.2021.101688_bib62","doi-asserted-by":"crossref","first-page":"993","DOI":"10.4330\/wjc.v6.i9.993","article-title":"Cardiac manifestations in systemic sclerosis","volume":"6","author":"Lambova","year":"2014","journal-title":"World J Cardiol"},{"key":"10.1016\/j.berh.2021.101688_bib63","doi-asserted-by":"crossref","first-page":"1571","DOI":"10.1002\/art.41308","article-title":"Cardiac intravoxel incoherent motion diffusion-weighted magnetic resonance imaging with T1 mapping to assess myocardial perfusion and fibrosis in systemic sclerosis: association with cardiac events from a prospective cohort study","volume":"72","author":"Terrier","year":"2020","journal-title":"Arthritis Rheum"},{"issue":"1","key":"10.1016\/j.berh.2021.101688_bib64","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.semarthrit.2019.06.013","article-title":"T1 mapping cardiac magnetic resonance imaging frequently detects subclinical diffuse myocardial fibrosis in systemic sclerosis patients","volume":"50","author":"Poindron","year":"2020","journal-title":"Semin Arthritis Rheum"},{"issue":"8","key":"10.1016\/j.berh.2021.101688_bib65","doi-asserted-by":"crossref","first-page":"1938","DOI":"10.1093\/rheumatology\/kez494","article-title":"Cardiac magnetic resonance predicts ventricular arrhythmias in scleroderma: the Scleroderma Arrhythmia Clinical Utility Study (SAnCtUS)","volume":"59","author":"Mavrogeni","year":"2020","journal-title":"Rheumatology"},{"issue":"Suppl 2","key":"10.1016\/j.berh.2021.101688_bib66","first-page":"1949","article-title":"Proposal of outcome measures to be used on a 12-month open label drug trial in juvinile systemic sclerosis. Results of the 3RD consenus meeting in Hamburg December 2018","volume":"78","author":"Foeldvari","year":"2019","journal-title":"Ann Rheum Dis"},{"issue":"9","key":"10.1016\/j.berh.2021.101688_bib67","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1016\/j.clinbiochem.2006.03.016","article-title":"Evaluation of cardiac laboratory markers in patients with systemic sclerosis","volume":"39","author":"Montagnana","year":"2006","journal-title":"Clin Biochem"},{"issue":"10","key":"10.1016\/j.berh.2021.101688_bib68","doi-asserted-by":"crossref","first-page":"1832","DOI":"10.1093\/rheumatology\/kes144","article-title":"Juvenile and young adult-onset systemic sclerosis share the same organ involvement in adulthood: data from the EUSTAR database","volume":"51","author":"Foeldvari","year":"2012","journal-title":"Rheumatology"},{"issue":"5","key":"10.1016\/j.berh.2021.101688_bib69","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1016\/0002-9343(84)90986-0","article-title":"Factors predicting development of renal involvement in progressive systemic sclerosis","volume":"76","author":"Steen","year":"1984","journal-title":"Am J Med"},{"issue":"9","key":"10.1016\/j.berh.2021.101688_bib70","doi-asserted-by":"crossref","first-page":"1613","DOI":"10.1002\/1529-0131(199809)41:9<1613::AID-ART11>3.0.CO;2-O","article-title":"Case-control study of corticosteroids and other drugs that either precipitate or protect from the development of scleroderma renal crisis","volume":"41","author":"Steen","year":"1998","journal-title":"Arthritis Rheum"},{"issue":"10 Pt 2","key":"10.1016\/j.berh.2021.101688_bib71","doi-asserted-by":"crossref","first-page":"e279","DOI":"10.1016\/j.lpm.2014.03.029","article-title":"Gastrointestinal involvement in systemic sclerosis","volume":"43","author":"Savarino","year":"2014","journal-title":"Presse Med"},{"issue":"6","key":"10.1016\/j.berh.2021.101688_bib72","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1097\/BOR.0000000000000117","article-title":"Evaluation and management of gastrointestinal manifestations in scleroderma","volume":"26","author":"Kirby","year":"2014","journal-title":"Curr Opin Rheumatol"},{"issue":"3","key":"10.1016\/j.berh.2021.101688_bib73","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1016\/j.rdc.2015.04.007","article-title":"Systemic sclerosis: gastrointestinal disease and its management","volume":"41","author":"Gyger","year":"2015","journal-title":"Rheum Dis Clin N Am"},{"issue":"6","key":"10.1016\/j.berh.2021.101688_bib74","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1097\/BOR.0000000000000645","article-title":"Gastrointestinal involvement in systemic sclerosis: an update","volume":"31","author":"McMahan","year":"2019","journal-title":"Curr Opin Rheumatol"},{"issue":"12","key":"10.1016\/j.berh.2021.101688_bib75","doi-asserted-by":"crossref","first-page":"4143","DOI":"10.1002\/art.34652","article-title":"A\u00a0preliminary disease severity score for juvenile systemic sclerosis","volume":"64","author":"La Torre","year":"2012","journal-title":"Arthritis Rheum"},{"issue":"11","key":"10.1016\/j.berh.2021.101688_bib76","doi-asserted-by":"crossref","first-page":"1444","DOI":"10.1002\/acr.23778","article-title":"Relationship between esophageal abnormalities on fluoroscopic esophagram and pulmonary function testing in juvenile systemic sclerosis","volume":"71","author":"Ambartsumyan","year":"2019","journal-title":"Arthritis Care Res"},{"issue":"7","key":"10.1016\/j.berh.2021.101688_bib77","doi-asserted-by":"crossref","first-page":"1280","DOI":"10.1002\/art.22987","article-title":"Development of a preliminary scleroderma gastrointestinal tract 1.0 quality of life instrument","volume":"57","author":"Khanna","year":"2007","journal-title":"Arthritis Rheum"},{"issue":"9","key":"10.1016\/j.berh.2021.101688_bib78","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1002\/art.24730","article-title":"Reliability and validity of the university of California, los angeles scleroderma clinical trial consortium gastrointestinal tract instrument","volume":"61","author":"Khanna","year":"2009","journal-title":"Arthritis Rheum"},{"issue":"7","key":"10.1016\/j.berh.2021.101688_bib79","doi-asserted-by":"crossref","first-page":"1488","DOI":"10.3899\/jrheum.091165","article-title":"Characteristics of joint involvement and relationships with systemic inflammation in systemic sclerosis: results from the EULAR Scleroderma Trial and Research Group (EUSTAR) database","volume":"37","author":"Avouac","year":"2010","journal-title":"J\u00a0Rheumatol"},{"issue":"12","key":"10.1016\/j.berh.2021.101688_bib80","doi-asserted-by":"crossref","first-page":"e189","DOI":"10.1097\/PHM.0000000000000611","article-title":"Changes over time and responsiveness of the Cochin hand function scale and mouth handicap in systemic sclerosis scale in patients with systemic sclerosis: a prospective observational study","volume":"95","author":"Nguyen","year":"2016","journal-title":"Am J Phys Med Rehabil"},{"issue":"6","key":"10.1016\/j.berh.2021.101688_bib81","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.1002\/art.1780400620","article-title":"The palpable tendon friction rub: an important physical examination finding in patients with systemic sclerosis","volume":"40","author":"Steen","year":"1997","journal-title":"Arthritis Rheum"},{"issue":"10","key":"10.1016\/j.berh.2021.101688_bib82","doi-asserted-by":"crossref","first-page":"1514","DOI":"10.1002\/acr.22867","article-title":"Comparison of the utility and validity of three scoring tools to measure skin involvement in patients with juvenile dermatomyositis","volume":"68","author":"Campanilho-Marques","year":"2016","journal-title":"Arthritis Care Res"},{"issue":"7","key":"10.1016\/j.berh.2021.101688_bib83","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.1093\/rheumatology\/key421","article-title":"Development and validation of a composite disease activity score for measurement of muscle and skin involvement in juvenile dermatomyositis","volume":"58","author":"Rosina","year":"2019","journal-title":"Rheumatology"},{"issue":"8","key":"10.1016\/j.berh.2021.101688_bib84","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1136\/annrheumdis-2016-209909","article-title":"Update of EULAR recommendations for the treatment of systemic sclerosis","volume":"76","author":"Kowal-Bielecka","year":"2017","journal-title":"Ann Rheum Dis"},{"issue":"11","key":"10.1016\/j.berh.2021.101688_bib85","doi-asserted-by":"crossref","first-page":"1820","DOI":"10.1002\/art.40560","article-title":"Treatment algorithms for systemic sclerosis according to experts","volume":"70","author":"Fernandez-Codina","year":"2018","journal-title":"Arthritis Rheum"}],"container-title":["Best Practice &amp; Research Clinical Rheumatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1521694221000309?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1521694221000309?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T17:20:37Z","timestamp":1761499237000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1521694221000309"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9]]},"references-count":85,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,9]]}},"alternative-id":["S1521694221000309"],"URL":"https:\/\/doi.org\/10.1016\/j.berh.2021.101688","relation":{},"ISSN":["1521-6942"],"issn-type":[{"value":"1521-6942","type":"print"}],"subject":[],"published":{"date-parts":[[2021,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Review for best practice in clinical rheumatology juvenile systemic sclerosis \u2013 Updates and practice points","name":"articletitle","label":"Article Title"},{"value":"Best Practice & Research Clinical Rheumatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.berh.2021.101688","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"101688"}}