{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T22:51:48Z","timestamp":1793314308315,"version":"4.5.0"},"reference-count":60,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,10,6]],"date-time":"2022-10-06T00:00:00Z","timestamp":1665014400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioactive Materials"],"published-print":{"date-parts":[[2023,4]]},"DOI":"10.1016\/j.bioactmat.2022.10.010","type":"journal-article","created":{"date-parts":[[2022,10,11]],"date-time":"2022-10-11T20:21:39Z","timestamp":1665519699000},"page":"312-324","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":34,"special_numbering":"C","title":["Enhancing cartilage repair with optimized supramolecular hydrogel-based scaffold and pulsed electromagnetic field"],"prefix":"10.1016","volume":"22","author":[{"given":"Yucong","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5927-6712","authenticated-orcid":false,"given":"Linlong","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2481-6894","authenticated-orcid":false,"given":"Ye","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1348-1494","authenticated-orcid":false,"given":"Bin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8555-4827","authenticated-orcid":false,"given":"Haixing","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0568-7118","authenticated-orcid":false,"given":"Meiling","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongkang","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5268-3443","authenticated-orcid":false,"given":"Erik I.","family":"Waldorff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8008-9636","authenticated-orcid":false,"given":"Nianli","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ingmar","family":"Viohl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sien","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liming","family":"Bian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wayne Yuk-Wai","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3981-2239","authenticated-orcid":false,"given":"Gang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.bioactmat.2022.10.010_bib1","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.jconrel.2003.09.007","article-title":"Transforming growth factor-\u03b21 release from oligo (poly (ethylene glycol) fumarate) hydrogels in conditions that model the cartilage wound healing environment","volume":"94","author":"Holland","year":"2004","journal-title":"Journal of controlled release"},{"key":"10.1016\/j.bioactmat.2022.10.010_bib2","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.biomaterials.2016.09.002","article-title":"Transplantation of allogenic chondrocytes with chitosan hydrogel-demineralized bone matrix hybrid scaffold to repair rabbit cartilage injury","volume":"108","author":"Man","year":"2016","journal-title":"Biomaterials"},{"key":"10.1016\/j.bioactmat.2022.10.010_bib3","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/270260","article-title":"Hydrogel-based nanocomposites and mesenchymal stem cells: a promising synergistic strategy for neurodegenerative disorders therapy","volume":"2013","author":"Albani","year":"2013","journal-title":"Sci. World J."},{"key":"10.1016\/j.bioactmat.2022.10.010_bib4","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.biomaterials.2016.12.015","article-title":"Fabrication of injectable high strength hydrogel based on 4-arm star PEG for cartilage tissue engineering","volume":"120","author":"Wang","year":"2017","journal-title":"Biomaterials"},{"key":"10.1016\/j.bioactmat.2022.10.010_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.carbpol.2020.116364","article-title":"Hyaluronic acid-Based wound dressings: a review","volume":"241","author":"Graca","year":"2020","journal-title":"Carbohydr. Polym."},{"issue":"14","key":"10.1016\/j.bioactmat.2022.10.010_bib6","doi-asserted-by":"crossref","first-page":"1774","DOI":"10.1002\/adfm.201202365","article-title":"Hyaluronic acid catechol: a biopolymer exhibiting a pH-dependent adhesive or cohesive property for human neural stem cell engineering","volume":"23","author":"Hong","year":"2013","journal-title":"Adv. Funct. Mater."},{"issue":"8","key":"10.1016\/j.bioactmat.2022.10.010_bib7","doi-asserted-by":"crossref","first-page":"4756","DOI":"10.1021\/acsabm.0c00294","article-title":"Cartilage-Derived progenitor cell-laden injectable hydrogel-an approach for cartilage tissue regeneration","volume":"3","author":"Li","year":"2020","journal-title":"ACS Appl. Bio Mater."},{"key":"10.1016\/j.bioactmat.2022.10.010_bib8","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-019-49435-z","article-title":"A modified collagen dressing induces transition of inflammatory to reparative phenotype of wound macrophages","volume":"9","author":"Das","year":"2019","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bioactmat.2022.10.010_bib9","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/j.carbpol.2018.06.114","article-title":"Chitosan based hydrogels and their applications for drug delivery in wound dressings: a review","volume":"199","author":"Hamedi","year":"2018","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.bioactmat.2022.10.010_bib10","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.carbpol.2017.10.036","article-title":"A composite hydrogel of chitosan\/heparin\/poly (gamma-glutamic acid) loaded with superoxide dismutase for wound healing","volume":"180","author":"Zhang","year":"2018","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.bioactmat.2022.10.010_bib11","doi-asserted-by":"crossref","DOI":"10.1016\/j.carbpol.2020.116025","article-title":"Alginate-based composite materials for wound dressing application:A mini review","volume":"236","author":"Varaprasad","year":"2020","journal-title":"Carbohydr. Polym."},{"issue":"11","key":"10.1016\/j.bioactmat.2022.10.010_bib12","doi-asserted-by":"crossref","first-page":"4139","DOI":"10.1039\/D1BM00482D","article-title":"A chondroitin sulfate based injectable hydrogel for delivery of stem cells in cartilage regeneration","volume":"9","author":"Li","year":"2021","journal-title":"Biomater Sci-Uk"},{"key":"10.1016\/j.bioactmat.2022.10.010_bib13","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.biomaterials.2016.05.043","article-title":"Mechanically resilient, injectable, and bioadhesive supramolecular gelatin hydrogels crosslinked by weak host-guest interactions assist cell infiltration and in situ tissue regeneration","volume":"101","author":"Feng","year":"2016","journal-title":"Biomaterials"},{"issue":"73","key":"10.1016\/j.bioactmat.2022.10.010_bib14","doi-asserted-by":"crossref","first-page":"42123","DOI":"10.1039\/C8RA07697A","article-title":"Tough and tissue-adhesive polyacrylamide\/collagen hydrogel with dopamine-grafted oxidized sodium alginate as crosslinker for cutaneous wound healing","volume":"8","author":"Bai","year":"2018","journal-title":"RSC Adv."},{"issue":"6349","key":"10.1016\/j.bioactmat.2022.10.010_bib15","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1126\/science.aah6362","article-title":"Tough adhesives for diverse wet surfaces","volume":"357","author":"Li","year":"2017","journal-title":"Science"},{"issue":"4","key":"10.1016\/j.bioactmat.2022.10.010_bib16","first-page":"998","article-title":"Advanced hydrogels for the repair of cartilage defects and regeneration","volume":"6","author":"Wei","year":"2021","journal-title":"Bioact. Mater."},{"issue":"14","key":"10.1016\/j.bioactmat.2022.10.010_bib17","doi-asserted-by":"crossref","first-page":"2724","DOI":"10.1002\/adma.201505336","article-title":"Tissue-integratable and biocompatible photogelation by the imine crosslinking reaction","volume":"28","author":"Yang","year":"2016","journal-title":"Adv. Mater."},{"issue":"8","key":"10.1016\/j.bioactmat.2022.10.010_bib18","doi-asserted-by":"crossref","first-page":"1707","DOI":"10.3390\/ijms18081707","article-title":"Artificial auricular cartilage using silk fibroin and polyvinyl alcohol hydrogel","volume":"18","author":"Lee","year":"2017","journal-title":"Int. J. Mol. Sci."},{"issue":"10","key":"10.1016\/j.bioactmat.2022.10.010_bib19","doi-asserted-by":"crossref","first-page":"2053","DOI":"10.1177\/0363546508328414","article-title":"Clinical efficacy of the microfracture technique for articular cartilage repair in the knee: an evidence-based systematic analysis","volume":"37","author":"Mithoefer","year":"2009","journal-title":"Am. J. Sports Med."},{"issue":"7","key":"10.1016\/j.bioactmat.2022.10.010_bib20","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1089\/scd.2008.0213","article-title":"Mesenchymal stem cell differentiation in an experimental cartilage defect: restriction of hypertrophy to bone-close neocartilage","volume":"18","author":"Steck","year":"2009","journal-title":"Stem Cell. Dev."},{"key":"10.1016\/j.bioactmat.2022.10.010_bib21","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1016\/S0020-1383(08)70003-2","article-title":"Fracture healing: the diamond concept","volume":"38","author":"Giannoudis","year":"2007","journal-title":"Injury"},{"issue":"3","key":"10.1016\/j.bioactmat.2022.10.010_bib22","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1002\/jbm.a.32405","article-title":"Can low frequency electromagnetic field help cartilage tissue engineering?","volume":"92","author":"Chang","year":"2010","journal-title":"J. Biomed. Mater. Res. Part A: An Official Journal of The Society for Biomaterials, The Japanese Society for Biomaterials, and The Australian Society for Biomaterials and the Korean Society for Biomaterials"},{"issue":"4","key":"10.1016\/j.bioactmat.2022.10.010_bib23","doi-asserted-by":"crossref","first-page":"269","DOI":"10.3109\/03008200109016841","article-title":"Effects of pulsed electromagnetic fields on human articular chondrocyte proliferation","volume":"42","author":"Mattei","year":"2001","journal-title":"Connect. Tissue Res."},{"issue":"1","key":"10.1016\/j.bioactmat.2022.10.010_bib24","doi-asserted-by":"crossref","first-page":"87","DOI":"10.4103\/0019-5413.173522","article-title":"Low dose short duration pulsed electromagnetic field effects on cultured human chondrocytes: an experimental study","volume":"50","author":"Anbarasan","year":"2016","journal-title":"Indian J. Orthop."},{"issue":"5","key":"10.1016\/j.bioactmat.2022.10.010_bib25","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0065561","article-title":"Pulsed electromagnetic fields increased the anti-inflammatory effect of A2A and A3 adenosine receptors in human T\/C-28a2 chondrocytes and hFOB 1.19 osteoblasts","volume":"8","author":"Vincenzi","year":"2013","journal-title":"PLoS One"},{"issue":"4","key":"10.1016\/j.bioactmat.2022.10.010_bib26","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1016\/j.orthres.2005.01.008","article-title":"Pulsed electromagnetic fields reduce knee osteoarthritic lesion progression in the aged Dunkin Hartley Guinea pig","volume":"23","author":"Fini","year":"2005","journal-title":"J. Orthop. Res."},{"issue":"10","key":"10.1016\/j.bioactmat.2022.10.010_bib27","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1016\/j.biopha.2007.03.001","article-title":"Effect of pulsed electromagnetic field stimulation on knee cartilage, subchondral and epyphiseal trabecular bone of aged Dunkin Hartley Guinea pigs","volume":"62","author":"Fini","year":"2008","journal-title":"Biomed. Pharmacother."},{"issue":"6","key":"10.1016\/j.bioactmat.2022.10.010_bib28","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/S1063-4584(03)00083-9","article-title":"Modification of osteoarthritis by pulsed electromagnetic field\u2014a morphological study","volume":"11","author":"Ciombor","year":"2003","journal-title":"Osteoarthritis Cartilage"},{"issue":"5","key":"10.1016\/j.bioactmat.2022.10.010_bib29","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1002\/jor.20530","article-title":"Cartilage repair with osteochondral autografts in sheep: effect of biophysical stimulation with pulsed electromagnetic fields","volume":"26","author":"Benazzo","year":"2008","journal-title":"J. Orthop. Res."},{"key":"10.1016\/j.bioactmat.2022.10.010_bib30","unstructured":"W.Y. Lee, W.-l. Tse, P.-c. Ho, C.W.-y. Wong, Y.-Y. Kwok, G. Li, Phase I Clinical Trial of Intra-articular Injection of Autologous Mesenchymal Stem Cells for the Treatment of Wrist Chondral Defect."},{"issue":"6","key":"10.1016\/j.bioactmat.2022.10.010_bib31","doi-asserted-by":"crossref","first-page":"2004","DOI":"10.1021\/bm400352d","article-title":"Bioinspired, calcium-free alginate hydrogels with tunable physical and mechanical properties and improved biocompatibility","volume":"14","author":"Lee","year":"2013","journal-title":"Biomacromolecules"},{"issue":"12","key":"10.1016\/j.bioactmat.2022.10.010_bib32","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1302\/2046-3758.1012.BJR-2021-0274.R1","article-title":"High slew rate pulsed electromagnetic field enhances bone consolidation and shortens daily treatment duration in distraction osteogenesis","volume":"10","author":"Li","year":"2021","journal-title":"Bone Joint Res."},{"issue":"3","key":"10.1016\/j.bioactmat.2022.10.010_bib33","first-page":"295","article-title":"Long-term follow-up of fracture nonunions treated with PEMFs","volume":"22","author":"Garland","year":"1991","journal-title":"Contemp. Orthop."},{"issue":"10","key":"10.1016\/j.bioactmat.2022.10.010_bib34","doi-asserted-by":"crossref","first-page":"2722","DOI":"10.1177\/03635465221105874","article-title":"Pulsed electromagnetic field enhances healing of a meniscal tear and mitigates posttraumatic osteoarthritis in a rat model","volume":"50","author":"Wang","year":"2022","journal-title":"Am. J. Sports Med."},{"issue":"9","key":"10.1016\/j.bioactmat.2022.10.010_bib35","doi-asserted-by":"crossref","first-page":"3800","DOI":"10.1096\/fj.201601181R","article-title":"Cystic fibrosis transmembrane conductance regulator mediates tenogenic differentiation of tendon\u2010derived stem cells and tendon repair: accelerating tendon injury healing by intervening in its downstream signaling","volume":"31","author":"Liu","year":"2017","journal-title":"Faseb. J."},{"issue":"1","key":"10.1016\/j.bioactmat.2022.10.010_bib36","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1093\/bioinformatics\/btp612","article-title":"DEGseq: an R package for identifying differentially expressed genes from RNA-seq data","volume":"26","author":"Wang","year":"2010","journal-title":"Bioinformatics"},{"issue":"26","key":"10.1016\/j.bioactmat.2022.10.010_bib37","doi-asserted-by":"crossref","first-page":"7460","DOI":"10.1016\/j.biomaterials.2014.05.055","article-title":"Articular chondrocytes and mesenchymal stem cells seeded on biodegradable scaffolds for the repair of cartilage in a rat osteochondral defect model","volume":"35","author":"Dahlin","year":"2014","journal-title":"Biomaterials"},{"issue":"6","key":"10.1016\/j.bioactmat.2022.10.010_bib38","doi-asserted-by":"crossref","first-page":"1354","DOI":"10.1016\/j.orthres.2005.05.009.1100230617","article-title":"Aged bovine chondrocytes display a diminished capacity to produce a collagen\u2010rich, mechanically functional cartilage extracellular matrix","volume":"23","author":"Tran\u2010Khanh","year":"2005","journal-title":"J. Orthop. Res."},{"issue":"10","key":"10.1016\/j.bioactmat.2022.10.010_bib39","doi-asserted-by":"crossref","first-page":"1728","DOI":"10.1016\/j.joca.2015.05.018","article-title":"Joint distraction attenuates osteoarthritis by reducing secondary inflammation, cartilage degeneration and subchondral bone aberrant change","volume":"23","author":"Chen","year":"2015","journal-title":"Osteoarthritis Cartilage"},{"issue":"4","key":"10.1016\/j.bioactmat.2022.10.010_bib40","first-page":"579","article-title":"Mesenchymal cell-based repair of large, full-thickness defects of articular cartilage, the Journal of bone and joint surgery","volume":"76","author":"Wakitani","year":"1994","journal-title":"Am. Vol."},{"issue":"14","key":"10.1016\/j.bioactmat.2022.10.010_bib41","doi-asserted-by":"crossref","first-page":"1830","DOI":"10.1093\/bioinformatics\/btt285","article-title":"Pathview: an R\/Bioconductor package for pathway-based data integration and visualization","volume":"29","author":"Luo","year":"2013","journal-title":"Bioinformatics"},{"issue":"W1","key":"10.1016\/j.bioactmat.2022.10.010_bib42","doi-asserted-by":"crossref","first-page":"W501","DOI":"10.1093\/nar\/gkx372","article-title":"Pathview Web: user friendly pathway visualization and data integration","volume":"45","author":"Luo","year":"2017","journal-title":"Nucleic Acids Res."},{"issue":"5849","key":"10.1016\/j.bioactmat.2022.10.010_bib43","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1126\/science.1147241","article-title":"Mussel-inspired surface chemistry for multifunctional coatings","volume":"318","author":"Lee","year":"2007","journal-title":"Science"},{"issue":"3","key":"10.1016\/j.bioactmat.2022.10.010_bib44","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1080\/15583724.2014.881373","article-title":"Dopa\/catechol-tethered polymers: bioadhesives and biomimetic adhesive materials","volume":"54","author":"Moulay","year":"2014","journal-title":"Polym. Rev."},{"issue":"5110","key":"10.1016\/j.bioactmat.2022.10.010_bib45","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1126\/science.8493529","article-title":"Tissue engineering","volume":"260","author":"Langer","year":"1993","journal-title":"Science"},{"issue":"6109","key":"10.1016\/j.bioactmat.2022.10.010_bib46","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1126\/science.1222454","article-title":"Unlike bone, cartilage regeneration remains elusive","volume":"338","author":"Huey","year":"2012","journal-title":"Science"},{"issue":"10","key":"10.1016\/j.bioactmat.2022.10.010_bib47","doi-asserted-by":"crossref","first-page":"3254","DOI":"10.1002\/art.22136","article-title":"Premature induction of hypertrophy during in vitro chondrogenesis of human mesenchymal stem cells correlates with calcification and vascular invasion after ectopic transplantation in SCID mice","volume":"54","author":"Pelttari","year":"2006","journal-title":"Arthritis Rheum.: Off. J. Am. College Rheumatol."},{"issue":"1","key":"10.1016\/j.bioactmat.2022.10.010_bib48","doi-asserted-by":"crossref","DOI":"10.3928\/01477447-20101123-10","article-title":"Low-frequency electromagnetic field exposure accelerates chondrocytic phenotype expression on chitosan substrate","volume":"34","author":"Chang","year":"2011","journal-title":"Orthopedics"},{"issue":"4","key":"10.1016\/j.bioactmat.2022.10.010_bib49","first-page":"495","article-title":"Differentiation of human umbilical cord-derived mesenchymal stem cells, WJ-MSCs, into chondrogenic cells in the presence of pulsed electromagnetic fields","volume":"27","author":"Esposito","year":"2013","journal-title":"In Vivo"},{"issue":"5","key":"10.1016\/j.bioactmat.2022.10.010_bib50","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1152\/japplphysiol.01216.2012","article-title":"Electromagnetic fields enhance chondrogenesis of human adipose-derived stem cells in a chondrogenic microenvironment in vitro","volume":"114","author":"Chen","year":"2013","journal-title":"J. Appl. Physiol."},{"issue":"4","key":"10.1016\/j.bioactmat.2022.10.010_bib51","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1002\/bem.20633","article-title":"Effects of low frequency electromagnetic fields on the chondrogenic differentiation of human mesenchymal stem cells","volume":"32","author":"Mayer\u2010Wagner","year":"2011","journal-title":"Bioelectromagnetics"},{"key":"10.1016\/j.bioactmat.2022.10.010_bib52","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.jcot.2020.09.034","article-title":"In vitro chondrogenic differentiation of human articular cartilage derived chondroprogenitors using pulsed electromagnetic field","volume":"14","author":"Vinod","year":"2021","journal-title":"J. Clin. Orthopaedics Trauma"},{"issue":"12","key":"10.1016\/j.bioactmat.2022.10.010_bib53","doi-asserted-by":"crossref","first-page":"E229","DOI":"10.1002\/term.1671","article-title":"Electromagnetic fields counteract IL\u20101\u03b2 activity during chondrogenesis of bovine mesenchymal stem cells","volume":"9","author":"Ongaro","year":"2015","journal-title":"J. Tissue Eng. Regen. Med."},{"issue":"5","key":"10.1016\/j.bioactmat.2022.10.010_bib54","doi-asserted-by":"crossref","first-page":"1584","DOI":"10.1002\/bit.27287","article-title":"Pulsed electromagnetic fields promote repair of focal articular cartilage defects with engineered osteochondral constructs","volume":"117","author":"Stefani","year":"2020","journal-title":"Biotechnol. Bioeng."},{"key":"10.1016\/j.bioactmat.2022.10.010_bib55","first-page":"60","article-title":"Pulsed electromagnetic field applications: a corporate perspective","volume":"9","author":"Waldorff","year":"2017","journal-title":"J. Orthop. Trans."},{"issue":"4","key":"10.1016\/j.bioactmat.2022.10.010_bib56","doi-asserted-by":"crossref","first-page":"3805","DOI":"10.1021\/acsnano.0c00959","article-title":"Magnetic measurement and stimulation of cellular and intracellular structures","volume":"14","author":"Wang","year":"2020","journal-title":"ACS Nano"},{"issue":"4136","key":"10.1016\/j.bioactmat.2022.10.010_bib57","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1126\/science.184.4136.575","article-title":"Augmentation of bone repair by inductively coupled electromagnetic fields","volume":"184","author":"Andrew","year":"1974","journal-title":"Science"},{"issue":"3","key":"10.1016\/j.bioactmat.2022.10.010_bib58","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1097\/BCO.0b013e3181d4880f","article-title":"Electromagnetic bone growth stimulation in patients with femoral neck fractures treated with screws: prospective randomized double-blind study","volume":"21","author":"Faldini","year":"2010","journal-title":"Curr. Orthopaedic Pract."},{"issue":"2","key":"10.1016\/j.bioactmat.2022.10.010_bib59","doi-asserted-by":"crossref","first-page":"67","DOI":"10.25100\/cm.v45i2.1479","article-title":"Electromagnetic stimulation as coadjuvant in the healing of diaphyseal femoral fractures: a randomized controlled trial","volume":"45","author":"Martinez-Rondanelli","year":"2014","journal-title":"Colomb. M\u00e9d."},{"key":"10.1016\/j.bioactmat.2022.10.010_bib60","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.jot.2020.10.007","article-title":"A novel pulsed electromagnetic field promotes distraction osteogenesis via enhancing osteogenesis and angiogenesis in a rat model","volume":"25","author":"Li","year":"2020","journal-title":"J. Orthopaedic Trans."}],"container-title":["Bioactive Materials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2452199X22004340?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2452199X22004340?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,10]],"date-time":"2025-11-10T14:39:46Z","timestamp":1762785586000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2452199X22004340"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4]]},"references-count":60,"alternative-id":["S2452199X22004340"],"URL":"https:\/\/doi.org\/10.1016\/j.bioactmat.2022.10.010","relation":{},"ISSN":["2452-199X"],"issn-type":[{"value":"2452-199X","type":"print"}],"subject":[],"published":{"date-parts":[[2023,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Enhancing cartilage repair with optimized supramolecular hydrogel-based scaffold and pulsed electromagnetic field","name":"articletitle","label":"Article Title"},{"value":"Bioactive Materials","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bioactmat.2022.10.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors. Publishing services by Elsevier B.V. on behalf of KeAi Communications Co. Ltd.","name":"copyright","label":"Copyright"}]}}