{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,8]],"date-time":"2026-08-08T16:58:34Z","timestamp":1786208314539,"version":"build-2736575974"},"reference-count":72,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,1,29]],"date-time":"2023-01-29T00:00:00Z","timestamp":1674950400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioactive Materials"],"published-print":{"date-parts":[[2023,7]]},"DOI":"10.1016\/j.bioactmat.2023.01.021","type":"journal-article","created":{"date-parts":[[2023,2,9]],"date-time":"2023-02-09T06:09:22Z","timestamp":1675922962000},"page":"273-290","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"special_numbering":"C","title":["Triple-functional bone adhesive with enhanced internal fixation, bacteriostasis and osteoinductive properties for open fracture repair"],"prefix":"10.1016","volume":"25","author":[{"given":"Yusheng","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shenghui","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shencai","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weilu","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qinfeng","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liangjie","family":"Tian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zilin","family":"Tan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9615-8459","authenticated-orcid":false,"given":"Yanjun","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"8","key":"10.1016\/j.bioactmat.2023.01.021_bib1","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1007\/s00113-021-01042-2","article-title":"[Open fractures]","volume":"124","author":"Omar","year":"2021","journal-title":"Unfallchirurg"},{"issue":"10","key":"10.1016\/j.bioactmat.2023.01.021_bib2","doi-asserted-by":"crossref","first-page":"1965","DOI":"10.1007\/s00264-017-3556-5","article-title":"Risk factors for infectious complications after open fractures; a systematic review and meta-analysis","volume":"41","author":"Kortram","year":"2017","journal-title":"Int. Orthop."},{"issue":"4","key":"10.1016\/j.bioactmat.2023.01.021_bib3","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.cjtee.2018.01.002","article-title":"The principles and practice of open fracture care","volume":"21","author":"Diwan","year":"2018","journal-title":"Chin. J. Traumatol."},{"issue":"3","key":"10.1016\/j.bioactmat.2023.01.021_bib4","doi-asserted-by":"crossref","first-page":"265","DOI":"10.2106\/JBJS.20.01103","article-title":"A reevaluation of the risk of infection based on time to debridement in open fractures: results of the GOLIATH meta-analysis of observational studies and limited trial data","volume":"103","author":"Foote","year":"2021","journal-title":"J Bone Joint Surg Am"},{"issue":"2","key":"10.1016\/j.bioactmat.2023.01.021_bib5","first-page":"339","article-title":"Prevention of infection in open fractures","volume":"31","author":"Zalavras","year":"2017","journal-title":"Infect. Dis. Clin."},{"issue":"22","key":"10.1016\/j.bioactmat.2023.01.021_bib6","doi-asserted-by":"crossref","first-page":"2280","DOI":"10.1001\/jama.2018.6452","article-title":"Effect of negative pressure wound therapy vs standard wound management on 12-month disability among adults with severe open fracture of the lower limb: the WOLLF randomized clinical trial","volume":"319","author":"Costa","year":"2018","journal-title":"JAMA"},{"key":"10.1016\/j.bioactmat.2023.01.021_bib7","first-page":"CD003764","article-title":"Antibiotics for preventing infection in open limb fractures","volume":"1","author":"Gosselin","year":"2004","journal-title":"Cochrane Database Syst. Rev."},{"key":"10.1016\/j.bioactmat.2023.01.021_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2020.120593","article-title":"Antibacterial, proangiogenic, and osteopromotive nanoglass paste coordinates regenerative process following bacterial infection in hard tissue","volume":"268","author":"Seo","year":"2021","journal-title":"Biomaterials"},{"issue":"3","key":"10.1016\/j.bioactmat.2023.01.021_bib9","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.jconrel.2010.04.002","article-title":"Sustained release of vancomycin from polyurethane scaffolds inhibits infection of bone wounds in a rat femoral segmental defect model","volume":"145","author":"Li","year":"2010","journal-title":"J. Contr. Release"},{"issue":"11","key":"10.1016\/j.bioactmat.2023.01.021_bib10","doi-asserted-by":"crossref","first-page":"2487","DOI":"10.2106\/JBJS.E.01126","article-title":"Antibiotic-loaded bone cement for infection prophylaxis in total joint replacement","volume":"88","author":"Jiranek","year":"2006","journal-title":"J Bone Joint Surg Am"},{"key":"10.1016\/j.bioactmat.2023.01.021_bib11","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.jconrel.2016.08.014","article-title":"A novel, multi-barrier, drug eluting calcium sulfate\/biphasic calcium phosphate biodegradable composite bone cement for treatment of experimental MRSA osteomyelitis in rabbit model","volume":"239","author":"Mistry","year":"2016","journal-title":"J. Contr. Release"},{"issue":"1","key":"10.1016\/j.bioactmat.2023.01.021_bib12","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.jconrel.2006.10.010","article-title":"Gentamicin extended release from an injectable polymeric implant","volume":"117","author":"Krasko","year":"2007","journal-title":"J. Contr. Release"},{"issue":"8","key":"10.1016\/j.bioactmat.2023.01.021_bib13","doi-asserted-by":"crossref","DOI":"10.3390\/biomedicines9080907","article-title":"3D-Printed ginsenoside Rb1-loaded mesoporous calcium silicate\/calcium sulfate scaffolds for inflammation inhibition and bone regeneration","volume":"9","author":"Chen","year":"2021","journal-title":"Biomedicines"},{"issue":"38","key":"10.1016\/j.bioactmat.2023.01.021_bib14","doi-asserted-by":"crossref","DOI":"10.1002\/adfm.202102465","article-title":"Flexible osteogenic glue as an all-in-one solution to assist fracture fixation and healing","volume":"31","author":"Tang","year":"2021","journal-title":"Adv. Funct. Mater."},{"issue":"1","key":"10.1016\/j.bioactmat.2023.01.021_bib15","doi-asserted-by":"crossref","DOI":"10.1007\/s00264-017-3504-4","article-title":"Nonunion and delayed union in lateral open wedge distal femoral osteotomies-a legitimate concern?","volume":"42","author":"Liska","year":"2018","journal-title":"Int. Orthop."},{"key":"10.1016\/j.bioactmat.2023.01.021_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2021.132000","article-title":"Biodegradable dual-crosslinked adhesive glue for fixation and promotion of osteogenesis","volume":"427","author":"Hou","year":"2022","journal-title":"Chem. Eng. J."},{"issue":"Suppl 4","key":"10.1016\/j.bioactmat.2023.01.021_bib17","doi-asserted-by":"crossref","first-page":"S58","DOI":"10.1016\/j.injury.2018.11.039","article-title":"The Masquelet technique in the treatment of a non-infected open complex fracture of the distal tibia with severe bone and soft tissue loss: a case report","volume":"49","author":"Demitri","year":"2018","journal-title":"Injury"},{"issue":"11","key":"10.1016\/j.bioactmat.2023.01.021_bib18","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1302\/2058-5241.1.000042","article-title":"The floating knee: a review on ipsilateral femoral and tibial fractures","volume":"1","author":"Mu\u00f1oz Vives","year":"2016","journal-title":"EFORT Open Rev"},{"issue":"1","key":"10.1016\/j.bioactmat.2023.01.021_bib19","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12891-020-03840-y","article-title":"External fixator combined with three different fixation methods of fibula for treatment of extra-articular open fractures of distal tibia and fibula: a retrospective study","volume":"22","author":"Sun","year":"2021","journal-title":"BMC Muscoskel. Disord."},{"issue":"6","key":"10.1016\/j.bioactmat.2023.01.021_bib20","doi-asserted-by":"crossref","first-page":"1569","DOI":"10.1148\/rg.236035159","article-title":"Fracture fixation","volume":"23","author":"Taljanovic","year":"2003","journal-title":"Radiographics"},{"key":"10.1016\/j.bioactmat.2023.01.021_bib21","first-page":"CD000339","article-title":"Extramedullary fixation implants and external fixators for extracapsular hip fractures in adults","volume":"1","author":"Parker","year":"2006","journal-title":"Cochrane Database Syst. Rev."},{"key":"10.1016\/j.bioactmat.2023.01.021_bib22","first-page":"CD006522","article-title":"Different methods of external fixation for treating distal radial fractures in adults","volume":"1","author":"Handoll","year":"2008","journal-title":"Cochrane Database Syst. Rev."},{"key":"10.1016\/j.bioactmat.2023.01.021_bib23","first-page":"CD006194","article-title":"External fixation versus conservative treatment for distal radial fractures in adults","volume":"3","author":"Handoll","year":"2007","journal-title":"Cochrane Database Syst. Rev."},{"key":"10.1016\/j.bioactmat.2023.01.021_bib24","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.ijsu.2017.03.085","article-title":"Incidence and risk factors for surgical site infection after open reduction and internal fixation of tibial plateau fracture: a systematic review and meta-analysis","volume":"41","author":"Shao","year":"2017","journal-title":"Int. J. Surg."},{"key":"10.1016\/j.bioactmat.2023.01.021_bib25","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.ijsu.2018.06.018","article-title":"Risk factors for surgical site infection following operative treatment of ankle fractures: a systematic review and meta-analysis","volume":"56","author":"Shao","year":"2018","journal-title":"Int. J. Surg."},{"issue":"1","key":"10.1016\/j.bioactmat.2023.01.021_bib26","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1021\/acsami.7b18141","article-title":"Injectable and degradable pH-responsive hydrogels via spontaneous amino-yne click reaction","volume":"10","author":"Huang","year":"2018","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"Suppl","key":"10.1016\/j.bioactmat.2023.01.021_bib27","doi-asserted-by":"crossref","first-page":"S53","DOI":"10.1016\/j.actbio.2015.07.019","article-title":"Reprint of: review of bioactive glass: from Hench to hybrids","volume":"23","author":"Jones","year":"2015","journal-title":"Acta Biomater."},{"issue":"31","key":"10.1016\/j.bioactmat.2023.01.021_bib28","doi-asserted-by":"crossref","first-page":"6167","DOI":"10.1039\/C7TB01221G","article-title":"Bioactive glasses in wound healing: hope or hype?","volume":"5","author":"Naseri","year":"2017","journal-title":"J. Mater. Chem. B"},{"issue":"2","key":"10.1016\/j.bioactmat.2023.01.021_bib29","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1039\/D0MH01498B","article-title":"Porous bioactive glass micro- and nanospheres with controlled morphology: developments, properties and emerging biomedical applications","volume":"8","author":"Zheng","year":"2021","journal-title":"Mater. Horiz."},{"issue":"23","key":"10.1016\/j.bioactmat.2023.01.021_bib30","doi-asserted-by":"crossref","DOI":"10.3390\/ijms20235960","article-title":"Bioactive glass applications in dentistry","volume":"20","author":"Skallevold","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.bioactmat.2023.01.021_bib31","doi-asserted-by":"crossref","DOI":"10.1016\/j.actbio.2014.11.004","article-title":"Bioactive glasses beyond bone and teeth: emerging applications in contact with soft tissues","volume":"13","author":"Miguez-Pacheco","year":"2015","journal-title":"Acta Biomater."},{"key":"10.1016\/j.bioactmat.2023.01.021_bib32","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.actbio.2021.08.023","article-title":"Immunomodulatory bioactive glasses for tissue regeneration","volume":"133","author":"Zheng","year":"2021","journal-title":"Acta Biomater."},{"key":"10.1016\/j.bioactmat.2023.01.021_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.carbpol.2020.115858","article-title":"pH-Responsive nanoparticles based on cholesterol\/imidazole modified oxidized-starch for targeted anticancer drug delivery","volume":"233","author":"Xu","year":"2020","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.bioactmat.2023.01.021_bib34","doi-asserted-by":"crossref","DOI":"10.1016\/j.carbpol.2022.119686","article-title":"3D-printing of oxidized starch-based hydrogels with superior hydration properties","volume":"292","author":"Qiu","year":"2022","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.bioactmat.2023.01.021_bib35","doi-asserted-by":"crossref","first-page":"1546","DOI":"10.1016\/j.foodchem.2016.10.138","article-title":"Molecular structure, functionality and applications of oxidized starches: a review","volume":"221","author":"Vanier","year":"2017","journal-title":"Food Chem."},{"key":"10.1016\/j.bioactmat.2023.01.021_bib36","doi-asserted-by":"crossref","first-page":"497","DOI":"10.3389\/fchem.2019.00497","article-title":"Toward highly dispersed mesoporous bioactive glass nanoparticles with high Cu concentration using Cu\/ascorbic acid complex as precursor","volume":"7","author":"Zheng","year":"2019","journal-title":"Front. Chem."},{"issue":"3","key":"10.1016\/j.bioactmat.2023.01.021_bib37","first-page":"890","article-title":"Hybrid gelatin\/oxidized chondroitin sulfate hydrogels incorporating bioactive glass nanoparticles with enhanced mechanical properties, mineralization, and osteogenic differentiation","volume":"6","author":"Zhou","year":"2021","journal-title":"Bioact. Mater."},{"key":"10.1016\/j.bioactmat.2023.01.021_bib38","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.matlet.2015.01.122","article-title":"A facile synthesis of novel mesoporous bioactive glass nanoparticles with various morphologies and tunable mesostructure by sacrificial liquid template method","volume":"148","author":"Liang","year":"2015","journal-title":"Mater. Lett."},{"issue":"4","key":"10.1016\/j.bioactmat.2023.01.021_bib39","first-page":"1073","article-title":"3D additive manufactured composite scaffolds with antibiotic-loaded lamellar fillers for bone infection prevention and tissue regeneration","volume":"6","author":"C\u00e1mara-Torres","year":"2021","journal-title":"Bioact. Mater."},{"issue":"16","key":"10.1016\/j.bioactmat.2023.01.021_bib40","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.201700015","article-title":"Bioprinted osteogenic and vasculogenic patterns for engineering 3D bone tissue","volume":"6","author":"Byambaa","year":"2017","journal-title":"Adv Healthc Mater"},{"issue":"10","key":"10.1016\/j.bioactmat.2023.01.021_bib41","doi-asserted-by":"crossref","first-page":"3135","DOI":"10.1007\/s11999-013-2855-4","article-title":"What is the rate of methicillin-resistant Staphylococcus aureus and Gram-negative infections in open fractures?","volume":"471","author":"Chen","year":"2013","journal-title":"Clin. Orthop. Relat. Res."},{"key":"10.1016\/j.bioactmat.2023.01.021_bib42","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.jgar.2017.06.002","article-title":"Linezolid activity against clinical Gram-positive cocci with advanced antimicrobial drug resistance in Iran","volume":"10","author":"Houri","year":"2017","journal-title":"J Glob Antimicrob Resist"},{"issue":"2","key":"10.1016\/j.bioactmat.2023.01.021_bib43","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1007\/s40272-018-0282-4","article-title":"The relationship between vancomycin trough concentrations and AUC\/MIC ratios in pediatric patients: a qualitative systematic review","volume":"20","author":"Tkachuk","year":"2018","journal-title":"Paediatr Drugs"},{"issue":"2","key":"10.1016\/j.bioactmat.2023.01.021_bib44","doi-asserted-by":"crossref","DOI":"10.1016\/j.cmi.2017.06.017","article-title":"Evaluation of vancomycin MIC creep in methicillin-resistant Staphylococcus aureus infections-a systematic review and meta-analysis","volume":"24","author":"Diaz","year":"2018","journal-title":"Clin. Microbiol. Infect."},{"issue":"Suppl 1","key":"10.1016\/j.bioactmat.2023.01.021_bib45","doi-asserted-by":"crossref","first-page":"S35","DOI":"10.1086\/491712","article-title":"The pharmacokinetic and pharmacodynamic properties of vancomycin","volume":"42","author":"Rybak","year":"2006","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.bioactmat.2023.01.021_bib46","first-page":"312","article-title":"Multifunctional zinc ion doped sol - gel derived mesoporous bioactive glass nanoparticles for biomedical applications","volume":"4","author":"Ne\u0161\u010d\u00e1kov\u00e1","year":"2019","journal-title":"Bioact. Mater."},{"key":"10.1016\/j.bioactmat.2023.01.021_bib47","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/j.cis.2017.03.008","article-title":"Sol-gel processing of bioactive glass nanoparticles: a review","volume":"249","author":"Zheng","year":"2017","journal-title":"Adv. Colloid Interface Sci."},{"issue":"13","key":"10.1016\/j.bioactmat.2023.01.021_bib48","doi-asserted-by":"crossref","first-page":"1764","DOI":"10.1016\/j.compscitech.2010.06.002","article-title":"Polymer\/bioactive glass nanocomposites for biomedical applications: a review","volume":"70","author":"Boccaccini","year":"2010","journal-title":"Compos. Sci. Technol."},{"key":"10.1016\/j.bioactmat.2023.01.021_bib49","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2022.121506","article-title":"Injectable adhesive hemostatic gel with tumor acidity neutralizer and neutrophil extracellular traps lyase for enhancing adoptive NK cell therapy prevents post-resection recurrence of hepatocellular carcinoma","volume":"284","author":"Cheng","year":"2022","journal-title":"Biomaterials"},{"issue":"14","key":"10.1016\/j.bioactmat.2023.01.021_bib50","doi-asserted-by":"crossref","DOI":"10.1002\/adfm.202007457","article-title":"Injectable self-healing natural biopolymer-based hydrogel adhesive with thermoresponsive reversible adhesion for minimally invasive surgery","volume":"31","author":"Zhou","year":"2021","journal-title":"Adv. Funct. Mater."},{"issue":"12","key":"10.1016\/j.bioactmat.2023.01.021_bib51","doi-asserted-by":"crossref","first-page":"2240","DOI":"10.1021\/acsbiomaterials.6b00470","article-title":"Designing porous bone tissue engineering scaffolds with enhanced mechanical properties from composite hydrogels composed of modified alginate, gelatin, and bioactive glass","volume":"2","author":"Sarker","year":"2016","journal-title":"ACS Biomater. Sci. Eng."},{"key":"10.1016\/j.bioactmat.2023.01.021_bib52","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.biomaterials.2018.08.044","article-title":"Antibacterial adhesive injectable hydrogels with rapid self-healing, extensibility and compressibility as wound dressing for joints skin wound healing","volume":"183","author":"Qu","year":"2018","journal-title":"Biomaterials"},{"key":"10.1016\/j.bioactmat.2023.01.021_bib53","doi-asserted-by":"crossref","first-page":"8631","DOI":"10.1038\/ncomms9631","article-title":"Atomic and vibrational origins of mechanical toughness in bioactive cement during setting","volume":"6","author":"Tian","year":"2015","journal-title":"Nat. Commun."},{"issue":"22","key":"10.1016\/j.bioactmat.2023.01.021_bib54","doi-asserted-by":"crossref","first-page":"2480","DOI":"10.2174\/0929867321666131212151855","article-title":"Current hydrogel solutions for repairing and regeneration of complex tissues","volume":"21","author":"Wang","year":"2014","journal-title":"Curr. Med. Chem."},{"issue":"1","key":"10.1016\/j.bioactmat.2023.01.021_bib55","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1007\/s40820-022-00827-3","article-title":"Highly flexible and broad-range mechanically tunable all-wood hydrogels with nanoscale channels via the hofmeister effect for human motion monitoring","volume":"14","author":"Yan","year":"2022","journal-title":"Nano-Micro Lett."},{"issue":"5","key":"10.1016\/j.bioactmat.2023.01.021_bib56","doi-asserted-by":"crossref","first-page":"301","DOI":"10.55095\/achot2006\/044","article-title":"Open fractures and infection","volume":"73","author":"Neubauer","year":"2006","journal-title":"Acta Chir. Orthop. Traumatol. Cech."},{"key":"10.1016\/j.bioactmat.2023.01.021_bib57","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.actbio.2015.08.006","article-title":"Antibacterial and conductive injectable hydrogels based on quaternized chitosan-graft-polyaniline\/oxidized dextran for tissue engineering","volume":"26","author":"Zhao","year":"2015","journal-title":"Acta Biomater."},{"key":"10.1016\/j.bioactmat.2023.01.021_bib58","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.biomaterials.2017.01.011","article-title":"Antibacterial anti-oxidant electroactive injectable hydrogel as self-healing wound dressing with hemostasis and adhesiveness for cutaneous wound healing","volume":"122","author":"Zhao","year":"2017","journal-title":"Biomaterials"},{"issue":"2","key":"10.1016\/j.bioactmat.2023.01.021_bib59","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1021\/acs.biomac.7b00979","article-title":"Dual function injectable hydrogel for controlled release of antibiotic and local antibacterial therapy","volume":"19","author":"Hoque","year":"2018","journal-title":"Biomacromolecules"},{"issue":"2","key":"10.1016\/j.bioactmat.2023.01.021_bib60","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.nano.2014.09.014","article-title":"Mesoporous silica nanoparticles in drug delivery and biomedical applications","volume":"11","author":"Wang","year":"2015","journal-title":"Nanomedicine"},{"key":"10.1016\/j.bioactmat.2023.01.021_bib61","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.biomaterials.2018.03.020","article-title":"Understanding interactions between biomaterials and biological systems using proteomics","volume":"167","author":"Othman","year":"2018","journal-title":"Biomaterials"},{"issue":"3","key":"10.1016\/j.bioactmat.2023.01.021_bib62","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1002\/jbm.a.31502","article-title":"Investigation on clotting and hemolysis characteristics of heparin-immobilized polyether sulfones biomembrane","volume":"85","author":"Hou","year":"2008","journal-title":"J. Biomed. Mater. Res."},{"issue":"49","key":"10.1016\/j.bioactmat.2023.01.021_bib63","doi-asserted-by":"crossref","first-page":"54488","DOI":"10.1021\/acsami.2c14103","article-title":"Strong biopolymer-based nanocomposite hydrogel adhesives with removability and reusability for damaged tissue closure and healing","volume":"14","author":"Tian","year":"2022","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.bioactmat.2023.01.021_bib64","article-title":"Antioxidant mesoporous Ce-doped bioactive glass nanoparticles with anti-inflammatory and pro-osteogenic activities","volume":"5","author":"Zheng","year":"2020","journal-title":"Mater Today Bio"},{"issue":"4","key":"10.1016\/j.bioactmat.2023.01.021_bib65","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1038\/nri2062","article-title":"Osteoimmunology: shared mechanisms and crosstalk between the immune and bone systems","volume":"7","author":"Takayanagi","year":"2007","journal-title":"Nat. Rev. Immunol."},{"issue":"41","key":"10.1016\/j.bioactmat.2023.01.021_bib66","doi-asserted-by":"crossref","first-page":"9404","DOI":"10.1039\/D0TB01379J","article-title":"Inflammation and biomaterials: role of the immune response in bone regeneration by inorganic scaffolds","volume":"8","author":"Sadowska","year":"2020","journal-title":"J. Mater. Chem. B"},{"issue":"4","key":"10.1016\/j.bioactmat.2023.01.021_bib67","doi-asserted-by":"crossref","DOI":"10.3390\/ma9040288","article-title":"Bioactive glass nanoparticles: from synthesis to materials design for biomedical applications","volume":"9","author":"Vichery","year":"2016","journal-title":"Materials"},{"issue":"4","key":"10.1016\/j.bioactmat.2023.01.021_bib68","doi-asserted-by":"crossref","first-page":"7078","DOI":"10.1021\/acsnano.1c00204","article-title":"Dual-dynamic-bond cross-linked antibacterial adhesive hydrogel sealants with on-demand removability for post-wound-closure and infected wound healing","volume":"15","author":"Liang","year":"2021","journal-title":"ACS Nano"},{"key":"10.1016\/j.bioactmat.2023.01.021_bib69","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1007\/978-1-4939-9167-9_12","article-title":"Mouse model of Staphylococcus aureus skin infection","volume":"1960","author":"Malachowa","year":"2019","journal-title":"Methods Mol. Biol."},{"issue":"3","key":"10.1016\/j.bioactmat.2023.01.021_bib70","doi-asserted-by":"crossref","first-page":"e52","DOI":"10.1002\/cpz1.52","article-title":"Murine models for staphylococcal infection","volume":"1","author":"Klopfenstein","year":"2021","journal-title":"Curr Protoc"},{"key":"10.1016\/j.bioactmat.2023.01.021_bib71","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.202201023","article-title":"Pseudocatalytic hydrogels with intrinsic antibacterial and photothermal activities for local treatment of subcutaneous abscesses and breast tumors","author":"Ma","year":"2022","journal-title":"Adv Healthc Mater"},{"issue":"5","key":"10.1016\/j.bioactmat.2023.01.021_bib72","doi-asserted-by":"crossref","DOI":"10.1111\/cpr.12669","article-title":"Exosomes derived from miR-375-overexpressing human adipose mesenchymal stem cells promote bone regeneration","volume":"52","author":"Chen","year":"2019","journal-title":"Cell Prolif"}],"container-title":["Bioactive Materials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2452199X23000336?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2452199X23000336?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,10]],"date-time":"2025-11-10T14:39:42Z","timestamp":1762785582000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2452199X23000336"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7]]},"references-count":72,"alternative-id":["S2452199X23000336"],"URL":"https:\/\/doi.org\/10.1016\/j.bioactmat.2023.01.021","relation":{},"ISSN":["2452-199X"],"issn-type":[{"value":"2452-199X","type":"print"}],"subject":[],"published":{"date-parts":[[2023,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Triple-functional bone adhesive with enhanced internal fixation, bacteriostasis and osteoinductive properties for open fracture repair","name":"articletitle","label":"Article Title"},{"value":"Bioactive Materials","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bioactmat.2023.01.021","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Authors. Publishing services by Elsevier B.V. on behalf of KeAi Communications Co. Ltd.","name":"copyright","label":"Copyright"}]}}