{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T15:26:51Z","timestamp":1794065211923,"version":"4.8.0"},"reference-count":66,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,2,7]],"date-time":"2024-02-07T00:00:00Z","timestamp":1707264000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100020732","name":"Innovative Research Team of High-level Local Universities in Shanghai","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100020732","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013804","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100013804","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioactive Materials"],"published-print":{"date-parts":[[2024,5]]},"DOI":"10.1016\/j.bioactmat.2024.02.011","type":"journal-article","created":{"date-parts":[[2024,2,14]],"date-time":"2024-02-14T14:04:45Z","timestamp":1707919485000},"page":"346-361","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":74,"special_numbering":"C","title":["Piezoelectric hydrogel for treatment of periodontitis through bioenergetic activation"],"prefix":"10.1016","volume":"35","author":[{"given":"Xin","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xingyi","family":"Wan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2300-0500","authenticated-orcid":false,"given":"Baiyan","family":"Sui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Quanhong","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhirong","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tingting","family":"Ding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiao","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuxiao","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhong Lin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1041-4533","authenticated-orcid":false,"given":"Linlin","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.bioactmat.2024.02.011_bib1","first-page":"1","article-title":"Periodontal diseases","volume":"3","author":"Kinane","year":"2017","journal-title":"Nat. Rev. Dis. Prim."},{"issue":"10159","key":"10.1016\/j.bioactmat.2024.02.011_bib2","doi-asserted-by":"crossref","first-page":"1736","DOI":"10.1016\/S0140-6736(18)32203-7","article-title":"Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980\u20132017: a systematic analysis for the Global Burden of Disease Study 2017","volume":"392","author":"Roth","year":"2018","journal-title":"Lancet"},{"issue":"7","key":"10.1016\/j.bioactmat.2024.02.011_bib3","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1038\/s41577-020-00488-6","article-title":"Local and systemic mechanisms linking periodontal disease and inflammatory comorbidities","volume":"21","author":"Hajishengallis","year":"2021","journal-title":"Nat. Rev. Immunol."},{"issue":"1","key":"10.1016\/j.bioactmat.2024.02.011_bib4","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1038\/nri3785","article-title":"Periodontitis: from microbial immune subversion to systemic inflammation","volume":"15","author":"Hajishengallis","year":"2015","journal-title":"Nat. Rev. Immunol."},{"issue":"6","key":"10.1016\/j.bioactmat.2024.02.011_bib5","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1038\/s41423-023-00998-y","article-title":"Immunomodulatory properties of mesenchymal stem cells\/dental stem cells and their therapeutic applications","volume":"20","author":"Li","year":"2023","journal-title":"Cell. Mol. Immunol."},{"issue":"4","key":"10.1016\/j.bioactmat.2024.02.011_bib6","article-title":"Nanorepairers rescue inflammation\u2010induced mitochondrial dysfunction in mesenchymal stem cells","volume":"9","author":"Zhai","year":"2022","journal-title":"Adv. Sci."},{"issue":"3","key":"10.1016\/j.bioactmat.2024.02.011_bib7","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1016\/j.mito.2011.01.009","article-title":"Mitochondrial dysfunction and genetic heterogeneity in chronic periodontitis","volume":"11","author":"Govindaraj","year":"2011","journal-title":"Mitochondrion"},{"issue":"1","key":"10.1016\/j.bioactmat.2024.02.011_bib8","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1111\/j.1600-0757.2012.00455.x","article-title":"Obesity, diabetes mellitus, atherosclerosis and chronic periodontitis: a shared pathology via oxidative stress and mitochondrial dysfunction?","volume":"64","author":"Bullon","year":"2000","journal-title":"Periodontology"},{"issue":"1","key":"10.1016\/j.bioactmat.2024.02.011_bib9","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1038\/s41413-022-00197-x","article-title":"LncRNA GACAT2 binds with protein PKM1\/2 to regulate cell mitochondrial function and cementogenesis in an inflammatory environment","volume":"10","author":"Li","year":"2022","journal-title":"Bone Res."},{"issue":"4","key":"10.1016\/j.bioactmat.2024.02.011_bib10","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1038\/nrm3772","article-title":"Metabolic requirements for the maintenance of self-renewing stem cells","volume":"15","author":"Ito","year":"2014","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"12","key":"10.1016\/j.bioactmat.2024.02.011_bib11","doi-asserted-by":"crossref","first-page":"2398","DOI":"10.1016\/j.cmet.2021.10.004","article-title":"Mitochondrial metabolism coordinates stage-specific repair processes in macrophages during wound healing","volume":"33","author":"Willenborg","year":"2021","journal-title":"Cell Metabol."},{"issue":"6342","key":"10.1016\/j.bioactmat.2024.02.011_bib12","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1126\/science.aam7928","article-title":"Inflammation and metabolism in tissue repair and regeneration","volume":"356","author":"Eming","year":"2017","journal-title":"Science"},{"key":"10.1016\/j.bioactmat.2024.02.011_bib13","doi-asserted-by":"crossref","DOI":"10.1016\/j.molmet.2022.101450","article-title":"Update on the effects of energy metabolism in bone marrow mesenchymal stem cells differentiation","volume":"58","author":"Ning","year":"2022","journal-title":"Mol. Metabol."},{"issue":"13","key":"10.1016\/j.bioactmat.2024.02.011_bib14","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.aay7608","article-title":"Bioenergetic-active materials enhance tissue regeneration by modulating cellular metabolic state","volume":"6","author":"Liu","year":"2020","journal-title":"Sci. Adv."},{"issue":"19","key":"10.1016\/j.bioactmat.2024.02.011_bib15","doi-asserted-by":"crossref","DOI":"10.1002\/advs.201900819","article-title":"Biomaterial-based metabolic regulation in regenerative engineering","volume":"6","author":"Ma","year":"2019","journal-title":"Adv. Sci."},{"key":"10.1016\/j.bioactmat.2024.02.011_bib16","first-page":"116","article-title":"Orchestration of energy metabolism and osteogenesis by Mg(2+) facilitates low-dose BMP-2-driven regeneration","volume":"18","author":"Lin","year":"2022","journal-title":"Bioact. Mater."},{"issue":"50","key":"10.1016\/j.bioactmat.2024.02.011_bib17","doi-asserted-by":"crossref","first-page":"E11741","DOI":"10.1073\/pnas.1813000115","article-title":"Citrate-based materials fuel human stem cells by metabonegenic regulation","volume":"115","author":"Ma","year":"2018","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"1","key":"10.1016\/j.bioactmat.2024.02.011_bib18","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-021-98625-1","article-title":"Electromagnetic stimulation increases mitochondrial function in osteogenic cells and promotes bone fracture repair","volume":"11","author":"Hollenberg","year":"2021","journal-title":"Sci. Rep."},{"issue":"2","key":"10.1016\/j.bioactmat.2024.02.011_bib19","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1007\/s00068-020-01324-1","article-title":"Electrical stimulation in bone tissue engineering treatments","volume":"46","author":"Leppik","year":"2020","journal-title":"Eur. J. Trauma Emerg. Surg."},{"issue":"1","key":"10.1016\/j.bioactmat.2024.02.011_bib20","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-019-47389-w","article-title":"Electrical stimulation shifts healing\/scarring towards regeneration in a rat limb amputation model","volume":"9","author":"Oliveira","year":"2019","journal-title":"Sci. Rep."},{"issue":"2","key":"10.1016\/j.bioactmat.2024.02.011_bib21","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1007\/s00068-019-01127-z","article-title":"Electrical stimulation-based bone fracture treatment, if it works so well why do not more surgeons use it?","volume":"46","author":"Bhavsar","year":"2020","journal-title":"Eur. J. Trauma Emerg. Surg."},{"issue":"4","key":"10.1016\/j.bioactmat.2024.02.011_bib22","doi-asserted-by":"crossref","DOI":"10.1002\/mds3.10090","article-title":"In situ electrical stimulation for enhanced bone growth: a mini\u2010review","volume":"3","author":"Khatua","year":"2020","journal-title":"Med. Devices Sens."},{"issue":"51","key":"10.1016\/j.bioactmat.2024.02.011_bib23","doi-asserted-by":"crossref","DOI":"10.1002\/adma.202106317","article-title":"Cell-Traction-triggered on-demand electrical stimulation for neuron-like differentiation","volume":"33","author":"Liu","year":"2021","journal-title":"Adv. Mater."},{"issue":"46","key":"10.1016\/j.bioactmat.2024.02.011_bib24","doi-asserted-by":"crossref","first-page":"51885","DOI":"10.1021\/acsami.0c10957","article-title":"Biological effects of a three-dimensionally printed Ti6Al4V scaffold coated with piezoelectric BaTiO(3) nanoparticles on bone formation","volume":"12","author":"Liu","year":"2020","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"8","key":"10.1016\/j.bioactmat.2024.02.011_bib25","doi-asserted-by":"crossref","first-page":"7279","DOI":"10.1021\/acsnano.6b02247","article-title":"Nanocomposite membranes enhance bone regeneration through restoring physiological electric microenvironment","volume":"10","author":"Zhang","year":"2016","journal-title":"ACS Nano"},{"key":"10.1016\/j.bioactmat.2024.02.011_bib26","article-title":"Piezocatalytic medicine: an emerging frontier using piezoelectric materials for biomedical applications","author":"Chen","year":"2023","journal-title":"Adv. Mater."},{"issue":"37","key":"10.1016\/j.bioactmat.2024.02.011_bib27","doi-asserted-by":"crossref","first-page":"43441","DOI":"10.1021\/acsami.3c08336","article-title":"A novel injectable piezoelectric hydrogel for periodontal disease treatment","volume":"15","author":"Roldan","year":"2023","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"32","key":"10.1016\/j.bioactmat.2024.02.011_bib28","doi-asserted-by":"crossref","DOI":"10.1002\/adma.202007429","article-title":"Electroactive biomaterials and systems for cell fate determination and tissue regeneration: design and applications","volume":"33","author":"Liu","year":"2021","journal-title":"Adv. Mater."},{"issue":"13","key":"10.1016\/j.bioactmat.2024.02.011_bib29","doi-asserted-by":"crossref","DOI":"10.1002\/advs.202100962","article-title":"Wireless localized electrical stimulation generated by an ultrasound-driven piezoelectric discharge regulates proinflammatory macrophage polarization","volume":"8","author":"Kong","year":"2021","journal-title":"Adv. Sci."},{"key":"10.1016\/j.bioactmat.2024.02.011_bib30","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.biomaterials.2018.07.011","article-title":"Cartilage repair in degenerative osteoarthritis mediated by squid type II collagen via immunomodulating activation of M2 macrophages, inhibiting apoptosis and hypertrophy of chondrocytes","volume":"180","author":"Dai","year":"2018","journal-title":"Biomaterials"},{"key":"10.1016\/j.bioactmat.2024.02.011_bib31","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2020.119841","article-title":"A well defect-suitable and high-strength biomimetic squid type II gelatin hydrogel promoted in situ costal cartilage regeneration via dynamic immunomodulation and direct induction manners","volume":"240","author":"Dai","year":"2020","journal-title":"Biomaterials"},{"key":"10.1016\/j.bioactmat.2024.02.011_bib32","first-page":"701","article-title":"A bioinspired and high-strengthed hydrogel for regeneration of perforated temporomandibular joint disc: construction and pleiotropic immunomodulatory effects","volume":"25","author":"Xu","year":"2023","journal-title":"Bioact. Mater."},{"issue":"8","key":"10.1016\/j.bioactmat.2024.02.011_bib33","doi-asserted-by":"crossref","first-page":"2429","DOI":"10.1111\/j.1551-2916.2012.05085.x","article-title":"Synthesis and size control of tetragonal barium titanate nanopowders by facile solvothermal method","volume":"95","author":"Lee","year":"2012","journal-title":"J. Am. Ceram. Soc."},{"key":"10.1016\/j.bioactmat.2024.02.011_bib34","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1016\/j.ijbiomac.2021.05.040","article-title":"Synthesis and characterization of C2C12-laden gelatin methacryloyl (GelMA) from marine and mammalian sources","volume":"183","author":"Elkhoury","year":"2021","journal-title":"Int. J. Biol. Macromol."},{"issue":"21","key":"10.1016\/j.bioactmat.2024.02.011_bib35","doi-asserted-by":"crossref","first-page":"17842","DOI":"10.1021\/acsami.8b01991","article-title":"Insights into the role of ferroelectric polarization in piezocatalysis of nanocrystalline BaTiO3","volume":"10","author":"Wu","year":"2018","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"4","key":"10.1016\/j.bioactmat.2024.02.011_bib36","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1038\/nmeth.3317","article-title":"HISAT: a fast spliced aligner with low memory requirements","volume":"12","author":"Kim","year":"2015","journal-title":"Nat. Methods"},{"issue":"4","key":"10.1016\/j.bioactmat.2024.02.011_bib37","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1038\/nmeth.1923","article-title":"Fast gapped-read alignment with Bowtie 2","volume":"9","author":"Langmead","year":"2012","journal-title":"Nat. Methods"},{"issue":"8","key":"10.1016\/j.bioactmat.2024.02.011_bib38","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1016\/j.molp.2020.06.009","article-title":"TBtools: an integrative toolkit developed for interactive analyses of big biological data","volume":"13","author":"Chen","year":"2020","journal-title":"Mol. Plant"},{"issue":"18","key":"10.1016\/j.bioactmat.2024.02.011_bib39","doi-asserted-by":"crossref","first-page":"4370","DOI":"10.7150\/thno.19888","article-title":"Human umbilical cord MSCs as new cell sources for promoting periodontal regeneration in inflammatory periodontal defect","volume":"7","author":"Shang","year":"2017","journal-title":"Theranostics"},{"key":"10.1016\/j.bioactmat.2024.02.011_bib40","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.archoralbio.2016.09.002","article-title":"Differential effects of total and partial sleep deprivation on salivary factors in Wistar rats","volume":"73","author":"Lasisi","year":"2017","journal-title":"Arch. Oral Biol."},{"issue":"30","key":"10.1016\/j.bioactmat.2024.02.011_bib41","doi-asserted-by":"crossref","first-page":"27297","DOI":"10.1021\/acsami.9b05013","article-title":"Tailoring bacteria response by piezoelectric stimulation","volume":"11","author":"Carvalho","year":"2019","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.bioactmat.2024.02.011_bib42","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.nanoen.2017.12.034","article-title":"Effective enhancement of piezocatalytic activity of BaTiO3 nanowires under ultrasonic vibration","volume":"45","author":"Wu","year":"2018","journal-title":"Nano Energy"},{"issue":"19","key":"10.1016\/j.bioactmat.2024.02.011_bib43","doi-asserted-by":"crossref","DOI":"10.1002\/smll.201704022","article-title":"Lead\u2010free perovskite nanowire\u2010employed piezopolymer for highly efficient flexible nanocomposite energy harvester","volume":"14","author":"Jeong","year":"2018","journal-title":"Small"},{"issue":"6","key":"10.1016\/j.bioactmat.2024.02.011_bib44","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1038\/nmat2732","article-title":"Harnessing traction-mediated manipulation of the cell\/matrix interface to control stem-cell fate","volume":"9","author":"Huebsch","year":"2010","journal-title":"Nat. Mater."},{"issue":"4","key":"10.1016\/j.bioactmat.2024.02.011_bib45","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1016\/j.jobcr.2020.10.011","article-title":"Determination of stress distribution on periodontal ligament and alveolar bone by various tooth movements\u2013A 3D FEM study","volume":"10","author":"Gupta","year":"2020","journal-title":"J. Oral Biol. Craniofacial Res."},{"key":"10.1016\/j.bioactmat.2024.02.011_bib46","doi-asserted-by":"crossref","DOI":"10.1016\/j.jdent.2020.103310","article-title":"Liraglutide regulates bone destruction and exhibits anti-inflammatory effects in periodontitis in vitro and in vivo","volume":"94","author":"Zhang","year":"2020","journal-title":"J. Dent."},{"issue":"6","key":"10.1016\/j.bioactmat.2024.02.011_bib47","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1007\/s13238-017-0385-7","article-title":"The role of mitochondria in osteogenic, adipogenic and chondrogenic differentiation of mesenchymal stem cells","volume":"8","author":"Li","year":"2017","journal-title":"Protein Cell"},{"issue":"2\u20133","key":"10.1016\/j.bioactmat.2024.02.011_bib48","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.diff.2014.09.002","article-title":"Osteogenic differentiation regulated by Rho-kinase in periodontal ligament cells","volume":"88","author":"Yamamoto","year":"2014","journal-title":"Differentiation"},{"key":"10.1016\/j.bioactmat.2024.02.011_bib49","doi-asserted-by":"crossref","DOI":"10.3389\/fbioe.2020.597661","article-title":"Stem cell mechanobiology and the role of biomaterials in governing mechanotransduction and matrix production for tissue regeneration","volume":"8","author":"Naqvi","year":"2020","journal-title":"Front. Bioeng. Biotechnol."},{"issue":"21","key":"10.1016\/j.bioactmat.2024.02.011_bib50","doi-asserted-by":"crossref","first-page":"E3039","DOI":"10.1073\/pnas.1602776113","article-title":"Myosin light chain phosphorylation enhances contraction of heart muscle via structural changes in both thick and thin filaments","volume":"113","author":"Kampourakis","year":"2016","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"8","key":"10.1016\/j.bioactmat.2024.02.011_bib51","doi-asserted-by":"crossref","first-page":"2097","DOI":"10.1084\/jem.20180421","article-title":"Ca(2+)-mitochondria axis drives cell division in hematopoietic stem cells","volume":"215","author":"Umemoto","year":"2018","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.bioactmat.2024.02.011_bib52","doi-asserted-by":"crossref","DOI":"10.1016\/j.scr.2021.102560","article-title":"Increasing cytosolic Ca(2+) levels restore cell proliferation and stem cell potency in aged MSCs","volume":"56","author":"Ahamad","year":"2021","journal-title":"Stem Cell Res."},{"key":"10.1016\/j.bioactmat.2024.02.011_bib53","doi-asserted-by":"crossref","DOI":"10.4061\/2011\/920178","article-title":"IP3 receptors, mitochondria, and Ca2+ signaling: implications for aging","volume":"2011","author":"Decuypere","year":"2011","journal-title":"J. Aging Res."},{"issue":"24","key":"10.1016\/j.bioactmat.2024.02.011_bib54","doi-asserted-by":"crossref","first-page":"6510","DOI":"10.1523\/JNEUROSCI.1256-07.2007","article-title":"Purinergic receptor-stimulated IP3-mediated Ca2+ release enhances neuroprotection by increasing astrocyte mitochondrial metabolism during aging","volume":"27","author":"Wu","year":"2007","journal-title":"J. Neurosci."},{"issue":"43","key":"10.1016\/j.bioactmat.2024.02.011_bib55","doi-asserted-by":"crossref","first-page":"17253","DOI":"10.1073\/pnas.1308887110","article-title":"Modulation of macrophage phenotype by cell shape","volume":"110","author":"McWhorter","year":"2013","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"5","key":"10.1016\/j.bioactmat.2024.02.011_bib56","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1016\/j.acthis.2016.04.011","article-title":"Preventive effects of electrical stimulation on inflammation-induced muscle mitochondrial dysfunction","volume":"118","author":"Tanaka","year":"2016","journal-title":"Acta Histochem."},{"issue":"5","key":"10.1016\/j.bioactmat.2024.02.011_bib57","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1111\/jre.12760","article-title":"Functional and cell surface characteristics of periodontal ligament cells (PDLCs) on RGD-synthetic polypeptide conjugate coatings","volume":"55","author":"Khorolsuren","year":"2020","journal-title":"J. Periodontal. Res."},{"key":"10.1016\/j.bioactmat.2024.02.011_bib58","series-title":"Mechanisms and Morphology of Cellular Injury, Adaptation, and Death, Pathologic Basis of Veterinary Disease","first-page":"2","author":"Miller","year":"2017"},{"issue":"4","key":"10.1016\/j.bioactmat.2024.02.011_bib59","doi-asserted-by":"crossref","DOI":"10.15252\/embr.202051606","article-title":"OXPHOS deficiency activates global adaptation pathways to maintain mitochondrial membrane potential","volume":"22","author":"Liu","year":"2021","journal-title":"EMBO Rep."},{"key":"10.1016\/j.bioactmat.2024.02.011_bib60","doi-asserted-by":"crossref","first-page":"87","DOI":"10.3389\/fcell.2020.00087","article-title":"Energy metabolism regulates stem cell pluripotency","volume":"8","author":"Tsogtbaatar","year":"2020","journal-title":"Front. Cell Dev. Biol."},{"issue":"11","key":"10.1016\/j.bioactmat.2024.02.011_bib61","doi-asserted-by":"crossref","first-page":"4872","DOI":"10.1073\/pnas.0903269107","article-title":"Geometric cues for directing the differentiation of mesenchymal stem cells","volume":"107","author":"Kilian","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.bioactmat.2024.02.011_bib62","doi-asserted-by":"crossref","first-page":"330","DOI":"10.3389\/fimmu.2020.00330","article-title":"Disruption of monocyte and macrophage homeostasis in periodontitis","volume":"11","author":"Almubarak","year":"2020","journal-title":"Front. Immunol."},{"key":"10.1016\/j.bioactmat.2024.02.011_bib63","doi-asserted-by":"crossref","first-page":"2588","DOI":"10.3389\/fimmu.2019.02588","article-title":"Spatial distribution of macrophages during callus formation and maturation reveals close crosstalk between macrophages and newly forming vessels","volume":"10","author":"Stefanowski","year":"2019","journal-title":"Front. Immunol."},{"key":"10.1016\/j.bioactmat.2024.02.011_bib64","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.actbio.2021.08.023","article-title":"Immunomodulatory bioactive glasses for tissue regeneration","volume":"133","author":"Zheng","year":"2021","journal-title":"Acta Biomater."},{"key":"10.1016\/j.bioactmat.2024.02.011_bib65","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.actbio.2017.01.056","article-title":"Promoting tissue regeneration by modulating the immune system","volume":"53","author":"Julier","year":"2017","journal-title":"Acta Biomater."},{"issue":"1","key":"10.1016\/j.bioactmat.2024.02.011_bib66","article-title":"Bioelectric modulation of macrophage polarization","volume":"6","author":"Li","year":"2016","journal-title":"Sci. Rep."}],"container-title":["Bioactive Materials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2452199X24000562?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2452199X24000562?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,5,11]],"date-time":"2024-05-11T04:04:02Z","timestamp":1715400242000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2452199X24000562"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5]]},"references-count":66,"alternative-id":["S2452199X24000562"],"URL":"https:\/\/doi.org\/10.1016\/j.bioactmat.2024.02.011","relation":{},"ISSN":["2452-199X"],"issn-type":[{"value":"2452-199X","type":"print"}],"subject":[],"published":{"date-parts":[[2024,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Piezoelectric hydrogel for treatment of periodontitis through bioenergetic activation","name":"articletitle","label":"Article Title"},{"value":"Bioactive Materials","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bioactmat.2024.02.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Publishing services by Elsevier B.V. on behalf of KeAi Communications Co. Ltd.","name":"copyright","label":"Copyright"}]}}