{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T06:15:47Z","timestamp":1784355347887,"version":"3.55.0"},"reference-count":72,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,2,24]],"date-time":"2024-02-24T00:00:00Z","timestamp":1708732800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100007156","name":"Innovation and Technology Commission - Hong Kong","doi-asserted-by":"publisher","award":["ITS\/090\/18"],"award-info":[{"award-number":["ITS\/090\/18"]}],"id":[{"id":"10.13039\/501100007156","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100020997","name":"Centre National de Recherches M\u00e9t\u00e9orologiques","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100020997","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002920","name":"Research Grants Council, University Grants Committee","doi-asserted-by":"publisher","award":["CUHK409\/23"],"award-info":[{"award-number":["CUHK409\/23"]}],"id":[{"id":"10.13039\/501100002920","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002920","name":"Research Grants Council, University Grants Committee","doi-asserted-by":"publisher","award":["N_CUHK409\/23"],"award-info":[{"award-number":["N_CUHK409\/23"]}],"id":[{"id":"10.13039\/501100002920","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002920","name":"Research Grants Council, University Grants Committee","doi-asserted-by":"publisher","award":["GRF 14121121"],"award-info":[{"award-number":["GRF 14121121"]}],"id":[{"id":"10.13039\/501100002920","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002920","name":"Research Grants Council, University Grants Committee","doi-asserted-by":"publisher","award":["GRF 14118620"],"award-info":[{"award-number":["GRF 14118620"]}],"id":[{"id":"10.13039\/501100002920","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002920","name":"Research Grants Council, University Grants Committee","doi-asserted-by":"publisher","award":["ECS24201720"],"award-info":[{"award-number":["ECS24201720"]}],"id":[{"id":"10.13039\/501100002920","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioactive Materials"],"published-print":{"date-parts":[[2024,6]]},"DOI":"10.1016\/j.bioactmat.2024.02.032","type":"journal-article","created":{"date-parts":[[2024,3,5]],"date-time":"2024-03-05T12:36:30Z","timestamp":1709642190000},"page":"221-237","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Engineering an extracellular matrix-functionalized, load-bearing tendon substitute for effective repair of large-to-massive tendon defects"],"prefix":"10.1016","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1526-8048","authenticated-orcid":false,"given":"Shuting","family":"Huang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Rao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meng","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9878-3781","authenticated-orcid":false,"given":"Anna M.","family":"Blocki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunyi","family":"Wen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dai Fei Elmer","family":"Ker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6067-6705","authenticated-orcid":false,"given":"Rocky S.","family":"Tuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5934-9085","authenticated-orcid":false,"given":"Dan Michelle","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.bioactmat.2024.02.032_bib1","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.jht.2011.07.004","article-title":"Tendon biomechanics and mechanobiology--a minireview of basic concepts and recent advancements","volume":"25","author":"Wang","year":"2012","journal-title":"J. Hand Ther."},{"issue":"20","key":"10.1016\/j.bioactmat.2024.02.032_bib2","doi-asserted-by":"crossref","first-page":"2138","DOI":"10.1056\/NEJMcp0800814","article-title":"Clinical practice. Rotator-cuff failure","volume":"358","author":"Matsen","year":"2008","journal-title":"N. Engl. J. Med."},{"issue":"10100","key":"10.1016\/j.bioactmat.2024.02.032_bib3","first-page":"1211","article-title":"Prevalence, Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries","volume":"390","author":"Disease","year":"2017","journal-title":"1990-2016: a systematic analysis for the Global Burden of Disease Study 2016, Lancet"},{"issue":"2","key":"10.1016\/j.bioactmat.2024.02.032_bib4","doi-asserted-by":"crossref","first-page":"219","DOI":"10.2106\/00004623-200402000-00002","article-title":"The outcome and repair integrity of completely arthroscopically repaired large and massive rotator cuff tears","volume":"86","author":"Galatz","year":"2004","journal-title":"J Bone Joint Surg Am"},{"issue":"16","key":"10.1016\/j.bioactmat.2024.02.032_bib5","doi-asserted-by":"crossref","first-page":"1482","DOI":"10.2106\/JBJS.L.01193","article-title":"Arthroscopic repair of massive contracted rotator cuff tears: aggressive release with anterior and posterior interval slides do not improve cuff healing and integrity","volume":"95","author":"Kim","year":"2013","journal-title":"J Bone Joint Surg Am"},{"issue":"6","key":"10.1016\/j.bioactmat.2024.02.032_bib6","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1002\/jor.22853","article-title":"Tendon regeneration and scar formation: the concept of scarless healing","volume":"33","author":"Galatz","year":"2015","journal-title":"J. Orthop. Res."},{"issue":"5","key":"10.1016\/j.bioactmat.2024.02.032_bib7","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/j.clinbiomech.2015.03.005","article-title":"The structural and mechanical properties of the Achilles tendon 2 years after surgical repair","volume":"30","author":"Geremia","year":"2015","journal-title":"Clin. Biomech."},{"key":"10.1016\/j.bioactmat.2024.02.032_bib8","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.addr.2015.03.004","article-title":"Strategies to engineer tendon\/ligament-to-bone interface: biomaterials, cells and growth factors","volume":"94","author":"Font Tellado","year":"2015","journal-title":"Adv. Drug Deliv. Rev."},{"issue":"3","key":"10.1016\/j.bioactmat.2024.02.032_bib9","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1007\/s12178-014-9230-2","article-title":"Updates in biological therapies for knee injuries: tendons","volume":"7","author":"Demange","year":"2014","journal-title":"Curr Rev Musculoskelet Med"},{"issue":"661","key":"10.1016\/j.bioactmat.2024.02.032_bib10","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.abl8814","article-title":"Advances toward transformative therapies for tendon diseases","volume":"14","author":"Freedman","year":"2022","journal-title":"Sci. Transl. Med."},{"issue":"1","key":"10.1016\/j.bioactmat.2024.02.032_bib11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/jor.20456","article-title":"Functional tissue engineering for tendon repair: a multidisciplinary strategy using mesenchymal stem cells, bioscaffolds, and mechanical stimulation","volume":"26","author":"Butler","year":"2008","journal-title":"J. Orthop. Res."},{"key":"10.1016\/j.bioactmat.2024.02.032_bib12","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.addr.2014.11.015","article-title":"Biologics for tendon repair","volume":"84","author":"Docheva","year":"2015","journal-title":"Adv. Drug Deliv. Rev."},{"issue":"12","key":"10.1016\/j.bioactmat.2024.02.032_bib13","doi-asserted-by":"crossref","first-page":"1596","DOI":"10.1002\/jor.20938","article-title":"Effect of fiber distribution and realignment on the nonlinear and inhomogeneous mechanical properties of human supraspinatus tendon under longitudinal tensile loading","volume":"27","author":"Lake","year":"2009","journal-title":"J. Orthop. Res."},{"issue":"3","key":"10.1016\/j.bioactmat.2024.02.032_bib14","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/j.jse.2009.10.020","article-title":"Extracellular matrix scaffold devices for rotator cuff repair","volume":"19","author":"Derwin","year":"2010","journal-title":"J. Shoulder Elbow Surg."},{"issue":"5","key":"10.1016\/j.bioactmat.2024.02.032_bib15","doi-asserted-by":"crossref","first-page":"381","DOI":"10.2165\/00007256-200333050-00004","article-title":"The roles of growth factors in tendon and ligament healing","volume":"33","author":"Molloy","year":"2003","journal-title":"Sports Med."},{"issue":"12","key":"10.1016\/j.bioactmat.2024.02.032_bib16","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1038\/nrm3902","article-title":"Extracellular matrix assembly: a multiscale deconstruction","volume":"15","author":"Mouw","year":"2014","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"3","key":"10.1016\/j.bioactmat.2024.02.032_bib17","article-title":"\"Tissue papers\" from organ-specific decellularized extracellular matrices","volume":"27","author":"Jakus","year":"2017","journal-title":"Adv. Funct. Mater."},{"issue":"12","key":"10.1016\/j.bioactmat.2024.02.032_bib18","doi-asserted-by":"crossref","first-page":"2665","DOI":"10.2106\/JBJS.E.01307","article-title":"Commercial extracellular matrix scaffolds for rotator cuff tendon repair. Biomechanical, biochemical, and cellular properties","volume":"88","author":"Derwin","year":"2006","journal-title":"J Bone Joint Surg Am"},{"issue":"1","key":"10.1016\/j.bioactmat.2024.02.032_bib19","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1586\/17434440.6.1.61","article-title":"Scaffolds for tendon and ligament repair: review of the efficacy of commercial products","volume":"6","author":"Chen","year":"2009","journal-title":"Expet Rev. Med. Dev."},{"issue":"2","key":"10.1016\/j.bioactmat.2024.02.032_bib20","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1016\/j.biotechadv.2013.12.012","article-title":"Decellularized tissue and cell-derived extracellular matrices as scaffolds for orthopaedic tissue engineering","volume":"32","author":"Cheng","year":"2014","journal-title":"Biotechnol. Adv."},{"issue":"6","key":"10.1016\/j.bioactmat.2024.02.032_bib21","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1089\/ten.teb.2018.0018","article-title":"Physical microenvironment-based inducible scaffold for stem cell differentiation and tendon regeneration","volume":"24","author":"Zhang","year":"2018","journal-title":"Tissue Eng Part B Rev"},{"key":"10.1016\/j.bioactmat.2024.02.032_bib22","first-page":"291","article-title":"Novel hybrid biocomposites for tendon grafts: the addition of silk to polydioxanone and poly(lactide-co-caprolactone) enhances material properties, in vitro and in vivo biocompatibility","volume":"25","author":"Shiroud Heidari","year":"2023","journal-title":"Bioact. Mater."},{"issue":"4","key":"10.1016\/j.bioactmat.2024.02.032_bib23","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1177\/03635465231152186","article-title":"A knitted PET patch enhances the maturation of regenerated tendons in bridging reconstruction of massive rotator cuff tears in a rabbit model","volume":"51","author":"Zhong","year":"2023","journal-title":"Am. J. Sports Med."},{"issue":"18","key":"10.1016\/j.bioactmat.2024.02.032_bib24","doi-asserted-by":"crossref","DOI":"10.1002\/adma.201904511","article-title":"Role of biomaterials and controlled architecture on tendon\/ligament repair and regeneration","volume":"32","author":"No","year":"2020","journal-title":"Adv. Mater."},{"key":"10.1016\/j.bioactmat.2024.02.032_bib25","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.actbio.2016.02.004","article-title":"Increasing the strength and bioactivity of collagen scaffolds using customizable arrays of 3D-printed polymer fibers","volume":"33","author":"Mozdzen","year":"2016","journal-title":"Acta Biomater."},{"issue":"7","key":"10.1016\/j.bioactmat.2024.02.032_bib26","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1016\/j.clinbiomech.2015.05.007","article-title":"Biomechanical evaluation of a novel suturing scheme for grafting load-bearing collagen scaffolds for rotator cuff repair","volume":"30","author":"Islam","year":"2015","journal-title":"Clin. Biomech."},{"key":"10.1016\/j.bioactmat.2024.02.032_bib27","doi-asserted-by":"crossref","first-page":"252","DOI":"10.22203\/eCM.v043a17","article-title":"Profiled polyethylene terephthalate filaments that incorporate collagen and calcium phosphate enhance ligamentisation and bone formation","volume":"43","author":"Tai","year":"2022","journal-title":"Eur. Cell. Mater."},{"issue":"5","key":"10.1016\/j.bioactmat.2024.02.032_bib28","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1002\/ca.22322","article-title":"Tensile properties of a morphologically split supraspinatus tendon","volume":"27","author":"Matsuhashi","year":"2014","journal-title":"Clin. Anat."},{"issue":"3","key":"10.1016\/j.bioactmat.2024.02.032_bib29","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1007\/s10439-015-1263-1","article-title":"Scaffolds for tendon and ligament repair and regeneration","volume":"43","author":"Ratcliffe","year":"2015","journal-title":"Ann. Biomed. Eng."},{"issue":"37","key":"10.1016\/j.bioactmat.2024.02.032_bib30","doi-asserted-by":"crossref","first-page":"9295","DOI":"10.1016\/j.biomaterials.2013.08.054","article-title":"Enhancement of tenogenic differentiation of human adipose stem cells by tendon-derived extracellular matrix","volume":"34","author":"Yang","year":"2013","journal-title":"Biomaterials"},{"issue":"6","key":"10.1016\/j.bioactmat.2024.02.032_bib31","doi-asserted-by":"crossref","first-page":"8172","DOI":"10.1096\/fj.201902377RR","article-title":"Tendon-derived extracellular matrix induces mesenchymal stem cell tenogenesis via an integrin\/transforming growth factor-beta crosstalk-mediated mechanism","volume":"34","author":"Wang","year":"2020","journal-title":"Faseb. J."},{"issue":"1","key":"10.1016\/j.bioactmat.2024.02.032_bib32","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1186\/s13287-022-03038-0","article-title":"Tenogenic induction of human adipose-derived stem cells by soluble tendon extracellular matrix: composition and transcriptomic analyses","volume":"13","author":"Rao","year":"2022","journal-title":"Stem Cell Res. Ther."},{"issue":"1","key":"10.1016\/j.bioactmat.2024.02.032_bib33","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1186\/s13287-017-0580-8","article-title":"Tissue-specific bioactivity of soluble tendon-derived and cartilage-derived extracellular matrices on adult mesenchymal stem cells","volume":"8","author":"Rothrauff","year":"2017","journal-title":"Stem Cell Res. Ther."},{"issue":"12","key":"10.1016\/j.bioactmat.2024.02.032_bib34","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1089\/ten.tec.2021.0150","article-title":"Frequently used strategies to isolate extracellular matrix proteins from human placenta and adipose tissue","volume":"27","author":"Hackethal","year":"2021","journal-title":"Tissue Eng. C Methods"},{"key":"10.1016\/j.bioactmat.2024.02.032_bib35","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1038\/s41413-017-0005-4","article-title":"Transforming growth factor-beta in stem cells and tissue homeostasis","volume":"6","author":"Xu","year":"2018","journal-title":"Bone Res"},{"issue":"4","key":"10.1016\/j.bioactmat.2024.02.032_bib36","first-page":"432","article-title":"Early complications from the use of porcine dermal collagen implants (Permacol) as bridging constructs in the repair of massive rotator cuff tears. A report of 4 cases","volume":"73","author":"Soler","year":"2007","journal-title":"Acta Orthop. Belg."},{"issue":"20","key":"10.1016\/j.bioactmat.2024.02.032_bib37","doi-asserted-by":"crossref","DOI":"10.1002\/adfm.201707107","article-title":"Functionally graded, bone- and tendon-like polyurethane for rotator cuff repair","volume":"28","author":"Ker","year":"2018","journal-title":"Adv. Funct. Mater."},{"key":"10.1016\/j.bioactmat.2024.02.032_bib38","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/j.actbio.2017.03.014","article-title":"An osteogenesis\/angiogenesis-stimulation artificial ligament for anterior cruciate ligament reconstruction","volume":"54","author":"Li","year":"2017","journal-title":"Acta Biomater."},{"key":"10.1016\/j.bioactmat.2024.02.032_bib39","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms12028","article-title":"Skin-inspired hydrogel-elastomer hybrids with robust interfaces and functional microstructures","volume":"7","author":"Yuk","year":"2016","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bioactmat.2024.02.032_bib40","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.jot.2020.02.012","article-title":"Evaluation of animal models and methods for assessing shoulder function after rotator cuff tear: a systematic review","volume":"26","author":"Liu","year":"2021","journal-title":"J Orthop Translat"},{"issue":"3","key":"10.1016\/j.bioactmat.2024.02.032_bib41","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1067\/mse.2002.122228","article-title":"The effect of fibrin clot on healing rat supraspinatus tendon defects","volume":"11","author":"Thomopoulos","year":"2002","journal-title":"J. Shoulder Elbow Surg."},{"key":"10.1016\/j.bioactmat.2024.02.032_bib42","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.actbio.2020.07.020","article-title":"Regeneration of the rotator cuff tendon-to-bone interface using umbilical cord-derived mesenchymal stem cells and gradient extracellular matrix scaffolds from adipose tissue in a rat model","volume":"114","author":"Yea","year":"2020","journal-title":"Acta Biomater."},{"issue":"4","key":"10.1016\/j.bioactmat.2024.02.032_bib43","first-page":"13","article-title":"A modified Mason-Allen technique for mini open transosseous rotator cuff repair","volume":"5","author":"Bhalerao","year":"2019","journal-title":"International Journal of Orthopaedics"},{"issue":"1","key":"10.1016\/j.bioactmat.2024.02.032_bib44","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.clinbiomech.2006.07.009","article-title":"Biomechanical comparison of double-loaded suture anchors using arthroscopic Mason-Allen stitches versus traditional transosseous suture technique and modified Mason-Allen stitches for rotator cuff repair","volume":"22","author":"Klinger","year":"2007","journal-title":"Clin. Biomech."},{"issue":"3","key":"10.1016\/j.bioactmat.2024.02.032_bib45","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1302\/0301-620X.76B3.8175836","article-title":"Mechanical strength of repairs of the rotator cuff","volume":"76","author":"Gerber","year":"1994","journal-title":"J Bone Joint Surg Br"},{"issue":"11","key":"10.1016\/j.bioactmat.2024.02.032_bib46","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1016\/j.joca.2012.08.006","article-title":"Limb Idleness Index (LII): a novel measurement of pain in a rat model of osteoarthritis","volume":"20","author":"Fu","year":"2012","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.bioactmat.2024.02.032_bib47","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.actbio.2017.01.041","article-title":"Alignment of collagen fiber in knitted silk scaffold for functional massive rotator cuff repair","volume":"51","author":"Zheng","year":"2017","journal-title":"Acta Biomater."},{"issue":"4","key":"10.1016\/j.bioactmat.2024.02.032_bib48","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1016\/j.jhsa.2009.12.025","article-title":"The effect of epitendinous suture technique on gliding resistance during cyclic motion after flexor tendon repair: a cadaveric study","volume":"35","author":"Moriya","year":"2010","journal-title":"J Hand Surg Am"},{"issue":"1","key":"10.1016\/j.bioactmat.2024.02.032_bib49","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1080\/10408340500526766","article-title":"The correlation coefficient: an overview","volume":"36","author":"Asuero","year":"2006","journal-title":"Crit. Rev. Anal. Chem."},{"issue":"3","key":"10.1016\/j.bioactmat.2024.02.032_bib50","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1007\/s12264-018-00331-y","article-title":"Gait assessment of pain and analgesics: comparison of the DigiGait and CatWalk gait imaging systems","volume":"35","author":"Xu","year":"2019","journal-title":"Neurosci. Bull."},{"issue":"5","key":"10.1016\/j.bioactmat.2024.02.032_bib51","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1016\/j.jbiomech.2003.09.019","article-title":"Supraspinatus tendon organizational and mechanical properties in a chronic rotator cuff tear animal model","volume":"37","author":"Gimbel","year":"2004","journal-title":"J. Biomech."},{"issue":"5","key":"10.1016\/j.bioactmat.2024.02.032_bib52","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1007\/BF00788278","article-title":"Quantitative assessment of myocardial collagen with picrosirius red staining and circularly polarized light","volume":"89","author":"Whittaker","year":"1994","journal-title":"Basic Res. Cardiol."},{"issue":"1","key":"10.1016\/j.bioactmat.2024.02.032_bib53","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1186\/s13018-021-02696-9","article-title":"Complex ruptures of the quadriceps tendon: a systematic review of surgical procedures and outcomes","volume":"16","author":"Oliva","year":"2021","journal-title":"J. Orthop. Surg. Res."},{"issue":"7","key":"10.1016\/j.bioactmat.2024.02.032_bib54","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1515\/hsz-2020-0386","article-title":"Marked difference in efficiency of the digestive enzymes pepsin, trypsin, chymotrypsin, and pancreatic elastase to cleave tightly folded proteins","volume":"402","author":"Fu","year":"2021","journal-title":"Biol. Chem."},{"issue":"12","key":"10.1016\/j.bioactmat.2024.02.032_bib55","doi-asserted-by":"crossref","first-page":"9317","DOI":"10.1016\/j.actbio.2013.07.022","article-title":"The effect of decellularized matrices on human tendon stem\/progenitor cell differentiation and tendon repair","volume":"9","author":"Yin","year":"2013","journal-title":"Acta Biomater."},{"issue":"8","key":"10.1016\/j.bioactmat.2024.02.032_bib56","doi-asserted-by":"crossref","first-page":"1768","DOI":"10.1016\/j.jbiomech.2006.07.025","article-title":"Is Achilles tendon compliance optimised for maximum muscle efficiency during locomotion?","volume":"40","author":"Lichtwark","year":"2007","journal-title":"J. Biomech."},{"issue":"9","key":"10.1016\/j.bioactmat.2024.02.032_bib57","doi-asserted-by":"crossref","first-page":"1168","DOI":"10.1016\/j.jse.2011.08.045","article-title":"Tensile and shear mechanical properties of rotator cuff repair patches","volume":"21","author":"Chaudhury","year":"2012","journal-title":"J. Shoulder Elbow Surg."},{"issue":"5","key":"10.1016\/j.bioactmat.2024.02.032_bib58","doi-asserted-by":"crossref","first-page":"1614","DOI":"10.1002\/jbm.a.34820","article-title":"Current tissue engineering strategies in anterior cruciate ligament reconstruction","volume":"102","author":"Leong","year":"2014","journal-title":"J. Biomed. Mater. Res."},{"issue":"1","key":"10.1016\/j.bioactmat.2024.02.032_bib59","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1002\/jor.24469","article-title":"Supraspinatus muscle and tendon stiffness changes after arthroscopic rotator cuff repair: a shear wave elastography assessment","volume":"38","author":"Itoigawa","year":"2020","journal-title":"J. Orthop. Res."},{"issue":"5","key":"10.1016\/j.bioactmat.2024.02.032_bib60","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1038\/s41578-019-0169-1","article-title":"The stiffness of living tissues and its implications for tissue engineering","volume":"5","author":"Guimar\u00e3es","year":"2020","journal-title":"Nat. Rev. Mater."},{"issue":"36","key":"10.1016\/j.bioactmat.2024.02.032_bib61","doi-asserted-by":"crossref","first-page":"5762","DOI":"10.1002\/adfm.201400828","article-title":"Tenogenic induction of human MSCs by anisotropically aligned collagen biotextiles","volume":"24","author":"Younesi","year":"2014","journal-title":"Adv. Funct. Mater."},{"issue":"11","key":"10.1016\/j.bioactmat.2024.02.032_bib62","doi-asserted-by":"crossref","first-page":"1825","DOI":"10.1016\/j.jhsa.2010.08.031","article-title":"Augmentation of zone II flexor tendon repair using growth differentiation factor 5 in a rabbit model","volume":"35","author":"Henn","year":"2010","journal-title":"J Hand Surg Am"},{"issue":"8","key":"10.1016\/j.bioactmat.2024.02.032_bib63","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1002\/term.3052","article-title":"Tendon regeneration induced by umbilical cord graft in a rabbit tendon defect model","volume":"14","author":"Wang","year":"2020","journal-title":"J Tissue Eng Regen Med"},{"key":"10.1016\/j.bioactmat.2024.02.032_bib64","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.trsl.2019.02.002","article-title":"The cellular basis of fibrotic tendon healing: challenges and opportunities","volume":"209","author":"Nichols","year":"2019","journal-title":"Transl. Res."},{"issue":"11","key":"10.1016\/j.bioactmat.2024.02.032_bib65","doi-asserted-by":"crossref","first-page":"1832","DOI":"10.1177\/0363546506289701","article-title":"Biomechanical comparison of traditional and locked suture configurations for arthroscopic repairs of the rotator cuff","volume":"34","author":"Koganti","year":"2006","journal-title":"Am. J. Sports Med."},{"issue":"6","key":"10.1016\/j.bioactmat.2024.02.032_bib66","doi-asserted-by":"crossref","first-page":"470","DOI":"10.55095\/achot2010\/078","article-title":"Polyetheretherketone (PEEK). Part II: application in clinical practice","volume":"77","author":"Pokorny","year":"2010","journal-title":"Acta Chir. Orthop. Traumatol. Cech."},{"issue":"3","key":"10.1016\/j.bioactmat.2024.02.032_bib69","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1152\/japplphysiol.00788.2015","article-title":"A method to test contractility of the supraspinatus muscle in mouse, rat, and rabbit","volume":"120","author":"Valencia","year":"2016","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.bioactmat.2024.02.032_bib70","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.jot.2020.01.001","article-title":"Reconstruction of large chronic rotator cuff tear can benefit from the bone-tendon composite autograft to restore the native bone-tendon interface","volume":"24","author":"Sun","year":"2020","journal-title":"J Orthop Translat"},{"issue":"9","key":"10.1016\/j.bioactmat.2024.02.032_bib67","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1016\/j.jse.2011.07.032","article-title":"Defining functional shoulder range of motion for activities of daily living","volume":"21","author":"Namdari","year":"2012","journal-title":"J. Shoulder Elbow Surg."},{"issue":"5","key":"10.1016\/j.bioactmat.2024.02.032_bib68","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1136\/bjsm.2009.058875","article-title":"Rehabilitation of shoulder impingement syndrome and rotator cuff injuries: an evidence-based review","volume":"44","author":"Ellenbecker","year":"2010","journal-title":"Br. J. Sports Med."},{"issue":"3","key":"10.1016\/j.bioactmat.2024.02.032_bib71","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/j.arthro.2007.01.014","article-title":"Biodegradable shoulder anchors have unique modes of failure","volume":"23","author":"Barber","year":"2007","journal-title":"Arthroscopy"},{"issue":"10","key":"10.1016\/j.bioactmat.2024.02.032_bib72","doi-asserted-by":"crossref","first-page":"2133","DOI":"10.1002\/jor.25678","article-title":"Preclinical tendon and ligament models: beyond the 3Rs (replacement, reduction, and refinement) to 5W1H (why, who, what, where, when, how)","volume":"41","author":"Little","year":"2023","journal-title":"J. Orthop. Res."}],"container-title":["Bioactive Materials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2452199X2400077X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2452199X2400077X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T00:07:49Z","timestamp":1778890069000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2452199X2400077X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6]]},"references-count":72,"alternative-id":["S2452199X2400077X"],"URL":"https:\/\/doi.org\/10.1016\/j.bioactmat.2024.02.032","relation":{},"ISSN":["2452-199X"],"issn-type":[{"value":"2452-199X","type":"print"}],"subject":[],"published":{"date-parts":[[2024,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Engineering an extracellular matrix-functionalized, load-bearing tendon substitute for effective repair of large-to-massive tendon defects","name":"articletitle","label":"Article Title"},{"value":"Bioactive Materials","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bioactmat.2024.02.032","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Publishing services by Elsevier B.V. on behalf of KeAi Communications Co. Ltd.","name":"copyright","label":"Copyright"}]}}