{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T09:04:03Z","timestamp":1780304643102,"version":"3.54.0"},"reference-count":61,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T00:00:00Z","timestamp":1768953600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005230","name":"Natural Science Foundation of Chongqing Municipality","doi-asserted-by":"publisher","award":["CSTB2023NSCQ-JQX0006"],"award-info":[{"award-number":["CSTB2023NSCQ-JQX0006"]}],"id":[{"id":"10.13039\/501100005230","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2025M781712"],"award-info":[{"award-number":["2025M781712"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007957","name":"Chongqing Municipal Education Commission","doi-asserted-by":"publisher","award":["KJZD-K202500412"],"award-info":[{"award-number":["KJZD-K202500412"]}],"id":[{"id":"10.13039\/501100007957","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82470988"],"award-info":[{"award-number":["82470988"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82470977"],"award-info":[{"award-number":["82470977"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioactive Materials"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.bioactmat.2026.01.033","type":"journal-article","created":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T19:22:44Z","timestamp":1771356164000},"page":"448-463","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["A nature-derived, strong adhesive hydrogel microsphere for wet tissue repair: Multifunctional and clinical potential"],"prefix":"10.1016","volume":"61","author":[{"given":"Liwen","family":"Zheng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jixian","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaxian","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianming","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuheng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xingrui","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ge","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan","family":"Pang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongmei","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ximu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.bioactmat.2026.01.033_bib1","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1007\/s12272-023-01428-3","article-title":"Distinctive role of inflammation in tissue repair and regeneration","volume":"46","author":"Choi","year":"2023","journal-title":"Archives of Pharmacal Research"},{"issue":"265","key":"10.1016\/j.bioactmat.2026.01.033_bib2","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.3009337","article-title":"Wound repair and regeneration: mechanisms, signaling, and translation","volume":"6","author":"Eming","year":"2014","journal-title":"Sci. Transl. Med."},{"issue":"7193","key":"10.1016\/j.bioactmat.2026.01.033_bib3","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1038\/nature07039","article-title":"Wound repair and regeneration","volume":"453","author":"Gurtner","year":"2008","journal-title":"Nature"},{"issue":"31","key":"10.1016\/j.bioactmat.2026.01.033_bib4","article-title":"Sugar functionalized collagen material for local modulation of innate immunity","volume":"12","author":"Taraballi","year":"2025","journal-title":"Adv. Sci."},{"issue":"2","key":"10.1016\/j.bioactmat.2026.01.033_bib5","doi-asserted-by":"crossref","DOI":"10.26599\/OSHM.2025.9610022","article-title":"Neutrophils linking periodontitis and Alzheimer's disease","volume":"1","author":"Li","year":"2025","journal-title":"Oral Sci. Homeost. Med."},{"issue":"1","key":"10.1016\/j.bioactmat.2026.01.033_bib6","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1186\/s13287-015-0082-5","article-title":"Three-dimensional spheroid cell culture of umbilical cord tissue-derived mesenchymal stromal cells leads to enhanced paracrine induction of wound healing","volume":"6","author":"Santos","year":"2015","journal-title":"Stem Cell Res. Ther."},{"issue":"12","key":"10.1016\/j.bioactmat.2026.01.033_bib7","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a005058","article-title":"Extracellular matrix degradation and remodeling in development and disease","volume":"3","author":"Lu","year":"2011","journal-title":"Cold Spring Harbor Perspect. Biol."},{"issue":"3","key":"10.1016\/j.bioactmat.2026.01.033_bib8","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1111\/iwj.12109","article-title":"Role of fibronectin in normal wound healing","volume":"12","author":"Lenselink","year":"2015","journal-title":"Int. Wound J."},{"issue":"7586","key":"10.1016\/j.bioactmat.2026.01.033_bib9","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1038\/nature17039","article-title":"Reparative inflammation takes charge of tissue regeneration","volume":"529","author":"Karin","year":"2016","journal-title":"Nature"},{"issue":"1","key":"10.1016\/j.bioactmat.2026.01.033_bib10","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1186\/s13287-016-0379-z","article-title":"Characteristics of responders to autologous bone marrow cell therapy for no-option critical limb ischemia","volume":"7","author":"Madaric","year":"2016","journal-title":"Stem Cell Res. Ther."},{"issue":"9","key":"10.1016\/j.bioactmat.2026.01.033_bib11","doi-asserted-by":"crossref","first-page":"1344","DOI":"10.1002\/adfm.201403631","article-title":"Injectable hydrogels with in situ double network formation enhance retention of transplanted stem cells","volume":"25","author":"Cai","year":"2015","journal-title":"Adv. Funct. Mater."},{"issue":"8","key":"10.1016\/j.bioactmat.2026.01.033_bib12","doi-asserted-by":"crossref","DOI":"10.3390\/ijms19082368","article-title":"Hydrogen sulfide-releasing fibrous membranes: potential patches for stimulating human stem cells proliferation and viability under oxidative stress","volume":"19","author":"Cacciotti","year":"2018","journal-title":"Int. J. Mol. Sci."},{"issue":"6","key":"10.1016\/j.bioactmat.2026.01.033_bib13","doi-asserted-by":"crossref","first-page":"2690","DOI":"10.1021\/acs.nanolett.0c04713","article-title":"Modulation of local overactive inflammation via injectable Hydrogel microspheres","volume":"21","author":"Bian","year":"2021","journal-title":"Nano Lett."},{"issue":"34","key":"10.1016\/j.bioactmat.2026.01.033_bib14","doi-asserted-by":"crossref","DOI":"10.1002\/advs.202504195","article-title":"Brachyury-activated fucoidan hydrogel microspheres rejuvenate degenerative intervertebral discs microenvironment","volume":"12","author":"Gong","year":"2025","journal-title":"Adv. Sci."},{"key":"10.1016\/j.bioactmat.2026.01.033_bib15","article-title":"Local recruitment of autologous stem cells via a targeting microgel for precise cartilage repair without surgery","author":"Zhang","year":"2025","journal-title":"Adv. Mater."},{"issue":"4","key":"10.1016\/j.bioactmat.2026.01.033_bib16","doi-asserted-by":"crossref","DOI":"10.1088\/1758-5090\/aceaaf","article-title":"Injectable rBMSCs-laden hydrogel microspheres loaded with naringin for osteomyelitis treatment","volume":"15","author":"Dong","year":"2023","journal-title":"Biofabrication"},{"key":"10.1016\/j.bioactmat.2026.01.033_bib17","doi-asserted-by":"crossref","first-page":"6","DOI":"10.3389\/fphar.2018.00006","article-title":"Three-dimensional in vitro cell culture models in drug discovery and drug repositioning","volume":"9","author":"Langhans","year":"2018","journal-title":"Front. Pharmacol."},{"issue":"1","key":"10.1016\/j.bioactmat.2026.01.033_bib18","doi-asserted-by":"crossref","DOI":"10.1038\/micronano.2017.76","article-title":"Parallel droplet microfluidics for high throughput cell encapsulation and synthetic microgel generation","volume":"4","author":"Headen","year":"2018","journal-title":"Microsys. Nanoeng."},{"issue":"1","key":"10.1016\/j.bioactmat.2026.01.033_bib19","doi-asserted-by":"crossref","DOI":"10.1088\/2631-7990\/acfcf2","article-title":"Engineering vascularized organotypic tissues via module assembly","volume":"6","author":"Zhou","year":"2024","journal-title":"Int. J. Extrem. Manuf."},{"issue":"9","key":"10.1016\/j.bioactmat.2026.01.033_bib20","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1038\/s41578-020-0209-x","article-title":"Engineered biomaterials for in situ tissue regeneration","volume":"5","author":"Gaharwar","year":"2020","journal-title":"Nat. Rev. Mater."},{"issue":"18","key":"10.1016\/j.bioactmat.2026.01.033_bib21","doi-asserted-by":"crossref","first-page":"17606","DOI":"10.1021\/acsnano.5c01184","article-title":"Nicotinamide adenine dinucleotide-loaded lubricated hydrogel microspheres with a three-pronged approach alleviate age-related osteoarthritis","volume":"19","author":"Lin","year":"2025","journal-title":"ACS Nano"},{"issue":"6349","key":"10.1016\/j.bioactmat.2026.01.033_bib22","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1126\/science.aah6362","article-title":"Tough adhesives for diverse wet surfaces","volume":"357","author":"Li","year":"2017","journal-title":"Science"},{"issue":"15","key":"10.1016\/j.bioactmat.2026.01.033_bib23","doi-asserted-by":"crossref","first-page":"5646","DOI":"10.1039\/C7CS00263G","article-title":"Microfluidic fabrication of microparticles for biomedical applications","volume":"47","author":"Li","year":"2018","journal-title":"Chem. Soc. Rev."},{"key":"10.1016\/j.bioactmat.2026.01.033_bib24","first-page":"562","article-title":"A cuttlefish ink nanoparticle-reinforced biopolymer hydrogel with robust adhesive and immunomodulatory features for treating oral ulcers in diabetes","volume":"39","author":"Xiang","year":"2024","journal-title":"Bioact. Mater."},{"key":"10.1016\/j.bioactmat.2026.01.033_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2024.122706","article-title":"Injectable bioadhesive hydrogel as a local nanomedicine depot for targeted regulation of inflammation and ferroptosis in rheumatoid arthritis","volume":"311","author":"Yang","year":"2024","journal-title":"Biomaterials"},{"issue":"6","key":"10.1016\/j.bioactmat.2026.01.033_bib26","doi-asserted-by":"crossref","DOI":"10.1002\/adfm.202211340","article-title":"Biomimetic natural biopolymer-based wet-tissue adhesive for tough adhesion, seamless sealed, emergency\/nonpressing hemostasis, and promoted wound healing","volume":"33","author":"Yang","year":"2023","journal-title":"Adv. Funct. Mater."},{"issue":"7","key":"10.1016\/j.bioactmat.2026.01.033_bib27","doi-asserted-by":"crossref","first-page":"6796","DOI":"10.1021\/acsami.8b20178","article-title":"Stimuli-responsive conductive nanocomposite hydrogels with high stretchability, self-healing, adhesiveness, and 3D printability for human motion sensing","volume":"11","author":"Deng","year":"2019","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"1","key":"10.1016\/j.bioactmat.2026.01.033_bib28","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1080\/10717544.2022.2070299","article-title":"Hydrogels for localized chemotherapy of liver cancer: a possible strategy for improved and safe liver cancer treatment","volume":"29","author":"Ma","year":"2022","journal-title":"Drug Deliv."},{"issue":"3","key":"10.1016\/j.bioactmat.2026.01.033_bib29","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1007\/s13346-023-01428-2","article-title":"Metal-polyphenol microgels for oral delivery of puerarin to alleviate the onset of diabetes","volume":"14","author":"Li","year":"2024","journal-title":"Drug Deliv. Transl. Res."},{"key":"10.1016\/j.bioactmat.2026.01.033_bib30","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.actbio.2025.05.031","article-title":"Multiscale characterization of ultrasmall fluorescent core-shell silica nanoparticles in cartilage and synovial joints reveals rapid cartilage penetration and sustained joint residence","volume":"200","author":"Fortin","year":"2025","journal-title":"Acta Biomater."},{"issue":"26","key":"10.1016\/j.bioactmat.2026.01.033_bib31","doi-asserted-by":"crossref","first-page":"37617","DOI":"10.1021\/acsami.5c06212","article-title":"One-pot preparation of an antioxidant, Anti-inflammatory, and analgesic hydrogel for oral mucosal lesions","volume":"17","author":"Lin","year":"2025","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"22","key":"10.1016\/j.bioactmat.2026.01.033_bib32","doi-asserted-by":"crossref","first-page":"32081","DOI":"10.1021\/acsami.5c06672","article-title":"3D printed human amnion-based bioactive hybrid dressings for effective management of complex infected wounds","volume":"17","author":"Sarkar","year":"2025","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"4","key":"10.1016\/j.bioactmat.2026.01.033_bib33","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/j.tibtech.2022.07.011","article-title":"Synovial joint-on-a-chip for modeling arthritis: progress, pitfalls, and potential","volume":"41","author":"Li","year":"2023","journal-title":"Trends Biotechnol."},{"issue":"4","key":"10.1016\/j.bioactmat.2026.01.033_bib34","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1177\/00220345231224709","article-title":"In situ photo-crosslinkable protein bioadhesive for bone graft fixation","volume":"103","author":"Yun","year":"2024","journal-title":"J. Dent. Res."},{"issue":"2","key":"10.1016\/j.bioactmat.2026.01.033_bib35","doi-asserted-by":"crossref","first-page":"302","DOI":"10.3390\/polym14020302","article-title":"The effect of salinized nano ZrO2 particles on the microstructure, hardness, and wear behavior of acrylic denture tooth nanocomposite","volume":"14","author":"El-Tamimi","year":"2022","journal-title":"Polymers"},{"issue":"2","key":"10.1016\/j.bioactmat.2026.01.033_bib36","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1039\/C9CS00285E","article-title":"Catechol-functionalized hydrogels: biomimetic design, adhesion mechanism, and biomedical applications","volume":"49","author":"Zhang","year":"2020","journal-title":"Chem. Soc. Rev."},{"key":"10.1016\/j.bioactmat.2026.01.033_bib37","doi-asserted-by":"crossref","DOI":"10.1016\/j.progpolymsci.2021.101388","article-title":"Recent advances in wet adhesives: adhesion mechanism, design principle and applications","volume":"116","author":"Cui","year":"2021","journal-title":"Prog. Polym. Sci."},{"issue":"19","key":"10.1016\/j.bioactmat.2026.01.033_bib38","doi-asserted-by":"crossref","DOI":"10.1002\/adma.201704640","article-title":"Bioinspired underwater adhesives by using the supramolecular toolbox","volume":"30","author":"Hofman","year":"2018","journal-title":"Adv. Mater."},{"issue":"10","key":"10.1016\/j.bioactmat.2026.01.033_bib39","doi-asserted-by":"crossref","DOI":"10.1016\/j.isci.2022.105106","article-title":"Underwater instant adhesion mechanism of self-assembled amphiphilic hemostatic granular hydrogel from Andrias davidianus skin secretion","volume":"25","author":"Liu","year":"2022","journal-title":"iScience"},{"issue":"25","key":"10.1016\/j.bioactmat.2026.01.033_bib40","doi-asserted-by":"crossref","DOI":"10.1002\/adma.202470196","article-title":"A nature-derived, hetero-structured, pro-healing bioadhesive patch for high-performance sealing of wet tissues","volume":"36","author":"Liu","year":"2024","journal-title":"Adv. Mater."},{"issue":"31","key":"10.1016\/j.bioactmat.2026.01.033_bib41","doi-asserted-by":"crossref","DOI":"10.1002\/adfm.201809110","article-title":"A bioinspired medical adhesive derived from skin secretion of Andrias davidianus for wound healing","volume":"29","author":"Deng","year":"2019","journal-title":"Adv. Funct. Mater."},{"issue":"50","key":"10.1016\/j.bioactmat.2026.01.033_bib42","article-title":"An adhesive bioink toward biofabrication under wet conditions","volume":"19","author":"Li","year":"2023","journal-title":"Small"},{"key":"10.1016\/j.bioactmat.2026.01.033_bib43","doi-asserted-by":"crossref","DOI":"10.1016\/j.compositesb.2024.111261","article-title":"A hydrogel derived from skin secretion of Andrias davidianus to facilitate bone regeneration","volume":"274","author":"Zhang","year":"2024","journal-title":"Compos. B Eng."},{"issue":"3","key":"10.1016\/j.bioactmat.2026.01.033_bib44","doi-asserted-by":"crossref","DOI":"10.1002\/smll.202101699","article-title":"A bioinspired hemostatic powder derived from the skin secretion of Andrias davidianus for rapid hemostasis and intraoral wound healing","volume":"18","author":"Zhang","year":"2022","journal-title":"Small"},{"issue":"12","key":"10.1016\/j.bioactmat.2026.01.033_bib45","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.1038\/ncb3268","article-title":"Extracellular rigidity sensing by talin isoform-specific mechanical linkages","volume":"17","author":"Austen","year":"2015","journal-title":"Nat. Cell Biol."},{"issue":"12","key":"10.1016\/j.bioactmat.2026.01.033_bib46","doi-asserted-by":"crossref","DOI":"10.1002\/adma.202417801","article-title":"Andrias davidianus derived glycosaminoglycans direct diabetic wound repair by reprogramming reparative macrophage glucolipid metabolism","volume":"37","author":"Yang","year":"2025","journal-title":"Adv. Mater."},{"issue":"51","key":"10.1016\/j.bioactmat.2026.01.033_bib47","doi-asserted-by":"crossref","DOI":"10.1002\/adfm.202409703","article-title":"Hydrophobic and adhesive elastomer encapsulation for anti-drying, non-swelling, and adhesive hydrogels","volume":"34","author":"Yuan","year":"2024","journal-title":"Adv. Funct. Mater."},{"issue":"3","key":"10.1016\/j.bioactmat.2026.01.033_bib48","article-title":"Toxic metal ion sequestration by amyloid-mediated fast coacervation","volume":"2","author":"Yang","year":"2021","journal-title":"Cell Rep. Phys. Sci."},{"issue":"1","key":"10.1016\/j.bioactmat.2026.01.033_bib49","doi-asserted-by":"crossref","first-page":"1890","DOI":"10.1038\/s41467-018-04263-z","article-title":"Hygroscopic compounds in spider aggregate glue remove interfacial water to maintain adhesion in humid conditions","volume":"9","author":"Singla","year":"2018","journal-title":"Nat. Commun."},{"issue":"14","key":"10.1016\/j.bioactmat.2026.01.033_bib50","doi-asserted-by":"crossref","first-page":"6857","DOI":"10.7150\/thno.112782","article-title":"Bioinspired nano-micron hydrogel microspheres for periodontitis therapy through synergistic multi-targeted remodeling of microenvironment","volume":"15","author":"Zhou","year":"2025","journal-title":"Theranostics"},{"issue":"9","key":"10.1016\/j.bioactmat.2026.01.033_bib51","doi-asserted-by":"crossref","first-page":"3750","DOI":"10.7150\/thno.107793","article-title":"A multifunctional injectable microsphere with enhanced near-infrared photo-antibacterial, ROS scavenging, and anti-inflammatory properties for periodontitis treatment","volume":"15","author":"Xiu","year":"2025","journal-title":"Theranostics"},{"key":"10.1016\/j.bioactmat.2026.01.033_bib52","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.actbio.2024.06.030","article-title":"Tissue-adhesive, stretchable and compressible physical double-crosslinked microgel-integrated hydrogels for dynamic wound care","volume":"184","author":"Li","year":"2024","journal-title":"Acta Biomater."},{"issue":"41","key":"10.1016\/j.bioactmat.2026.01.033_bib53","doi-asserted-by":"crossref","DOI":"10.1002\/adma.202408538","article-title":"Self-growing hydrogel bioadhesives for chronic wound management","volume":"36","author":"Zheng","year":"2024","journal-title":"Adv. Mater."},{"key":"10.1016\/j.bioactmat.2026.01.033_bib54","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2024.130680","article-title":"Polymerizable rotaxane of cucurbituril protecting dopamine based adhesive hydrogels","volume":"265","author":"Gao","year":"2024","journal-title":"Int. J. Biol. Macromol."},{"issue":"3","key":"10.1016\/j.bioactmat.2026.01.033_bib55","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1038\/s41570-024-00673-4","article-title":"Catechol redox maintenance in mussel adhesion","volume":"9","author":"Wang","year":"2025","journal-title":"Nat. Rev. Chem"},{"issue":"3","key":"10.1016\/j.bioactmat.2026.01.033_bib56","doi-asserted-by":"crossref","first-page":"2561","DOI":"10.1021\/acsnano.6b05318","article-title":"Mussel-inspired adhesive and tough hydrogel based on nanoclay confined dopamine polymerization","volume":"11","author":"Han","year":"2017","journal-title":"ACS Nano"},{"key":"10.1016\/j.bioactmat.2026.01.033_bib57","article-title":"Enzymatic crosslinking of coacervates yields high-strength and reconstitutable biomedical adhesives","author":"Dutta","year":"2025","journal-title":"Adv. Healthcare Mater."},{"issue":"3","key":"10.1016\/j.bioactmat.2026.01.033_bib58","doi-asserted-by":"crossref","first-page":"87","DOI":"10.3390\/biomimetics7030087","article-title":"The role of the extracellular matrix (ECM) in wound healing: a review","volume":"7","author":"Diller","year":"2022","journal-title":"Biomimetics"},{"key":"10.1016\/j.bioactmat.2026.01.033_bib59","first-page":"482","article-title":"Bioinspired Andrias davidianus-derived wound dressings for localized drug-elution","volume":"15","author":"Liu","year":"2022","journal-title":"Bioact. Mater."},{"issue":"5","key":"10.1016\/j.bioactmat.2026.01.033_bib60","article-title":"Efficient scarless skin regeneration enabled by loading micronized amnion in a bioinspired adhesive wound dressing","volume":"4","author":"Zhang","year":"2023","journal-title":"Aggregate"},{"issue":"26","key":"10.1016\/j.bioactmat.2026.01.033_bib61","doi-asserted-by":"crossref","DOI":"10.1002\/adfm.202315590","article-title":"Acupoint therapy with injectable, pro-healing stem cell-loaded hydrogel microspheres promotes skin wound healing","volume":"34","author":"Yan","year":"2024","journal-title":"Adv. Funct. Mater."}],"container-title":["Bioactive Materials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2452199X26000344?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2452199X26000344?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T08:15:42Z","timestamp":1780301742000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2452199X26000344"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":61,"alternative-id":["S2452199X26000344"],"URL":"https:\/\/doi.org\/10.1016\/j.bioactmat.2026.01.033","relation":{},"ISSN":["2452-199X"],"issn-type":[{"value":"2452-199X","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A nature-derived, strong adhesive hydrogel microsphere for wet tissue repair: Multifunctional and clinical potential","name":"articletitle","label":"Article Title"},{"value":"Bioactive Materials","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bioactmat.2026.01.033","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Publishing services by Elsevier B.V. on behalf of KeAi Communications Co. Ltd.","name":"copyright","label":"Copyright"}]}}