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Sci."},{"key":"10.1016\/j.bioactmat.2026.06.041_bib79","doi-asserted-by":"crossref","DOI":"10.3389\/fbioe.2023.1184325","article-title":"Oxygen metabolism analysis of a single organoid for non-invasive discrimination of cancer subpopulations with different growth capabilities","volume":"11","author":"Nashimoto","year":"2023","journal-title":"Front. Bioeng. Biotechnol."},{"issue":"1","key":"10.1016\/j.bioactmat.2026.06.041_bib80","doi-asserted-by":"crossref","first-page":"14","DOI":"10.3390\/bios8010014","article-title":"Self-organized nanostructure modified microelectrode for sensitive electrochemical glutamate detection in stem cells-derived brain organoids","volume":"8","author":"Nasr","year":"2018","journal-title":"Biosensors"},{"key":"10.1016\/j.bioactmat.2026.06.041_bib81","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2020.112852","article-title":"Epitope imprinting of alpha-synuclein for sensing in Parkinson's brain organoid culture medium","volume":"175","author":"Lee","year":"2021","journal-title":"Biosens. Bioelectron."},{"issue":"21","key":"10.1016\/j.bioactmat.2026.06.041_bib82","doi-asserted-by":"crossref","first-page":"6217","DOI":"10.1039\/D2SC00809B","article-title":"Dysfunction of vesicular storage in young-onset Parkinson's patient-derived dopaminergic neurons and organoids revealed by single cell electrochemical cytometry","volume":"13","author":"Zhu","year":"2022","journal-title":"Chem. Sci."},{"key":"10.1016\/j.bioactmat.2026.06.041_bib83","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2024.155355","article-title":"Drug evaluation platform based on non-destructive and real-time in situ organoid fate state monitoring by graphene field-effect transistor","volume":"498","author":"Tian","year":"2024","journal-title":"Chem. Eng. J."},{"issue":"6","key":"10.1016\/j.bioactmat.2026.06.041_bib84","doi-asserted-by":"crossref","DOI":"10.1002\/smll.202409571","article-title":"Heart-on-a-miniscope: a miniaturized solution for electrophysiological drug screening in cardiac organoids","volume":"21","author":"Tirgar","year":"2025","journal-title":"Small"},{"key":"10.1016\/j.bioactmat.2026.06.041_bib85","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2022.115024","article-title":"Photoelectrochemical imaging of single cardiomyocytes and monitoring of their action potentials through contact force manipulation of organoids","volume":"223","author":"Jacques","year":"2023","journal-title":"Biosens. Bioelectron."},{"issue":"2","key":"10.1016\/j.bioactmat.2026.06.041_bib86","doi-asserted-by":"crossref","DOI":"10.1002\/adma.202506793","article-title":"3D spatiotemporal electrophysiology of cardiac organoids using shell microelectrode arrays","volume":"38","author":"Choi","year":"2026","journal-title":"Adv. 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Commun."},{"issue":"12","key":"10.1016\/j.bioactmat.2026.06.041_bib89","doi-asserted-by":"crossref","first-page":"1836","DOI":"10.1038\/s41587-023-02081-3","article-title":"Kirigami electronics for long-term electrophysiological recording of human neural organoids and assembloids","volume":"42","author":"Yang","year":"2024","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.bioactmat.2026.06.041_bib90","doi-asserted-by":"crossref","DOI":"10.1016\/j.addr.2023.115074","article-title":"Spectroscopic techniques for monitoring stem cell and organoid proliferation in 3D environments for therapeutic development","volume":"201","author":"Mao","year":"2023","journal-title":"Adv. Drug Deliv. Rev."},{"issue":"1","key":"10.1016\/j.bioactmat.2026.06.041_bib91","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1186\/s11658-022-00347-3","article-title":"Raman microspectroscopy fingerprinting of organoid differentiation state","volume":"27","author":"Tubbesing","year":"2022","journal-title":"Cell. Mol. Biol. Lett."},{"issue":"34","key":"10.1016\/j.bioactmat.2026.06.041_bib92","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.abj2800","article-title":"Spectroscopic label-free microscopy of changes in live cell chromatin and biochemical composition in transplantable organoids","volume":"7","author":"Pettinato","year":"2021","journal-title":"Sci. Adv."},{"issue":"9","key":"10.1016\/j.bioactmat.2026.06.041_bib93","doi-asserted-by":"crossref","first-page":"5029","DOI":"10.1021\/acs.analchem.4c05661","article-title":"Label-free detection of biochemical changes during cortical organoid maturation via Raman spectroscopy and machine learning","volume":"97","author":"Bruno","year":"2025","journal-title":"Anal. Chem."},{"issue":"38","key":"10.1016\/j.bioactmat.2026.06.041_bib94","doi-asserted-by":"crossref","first-page":"50267","DOI":"10.1021\/acsami.4c08629","article-title":"Cisplatin-induced metabolic responses measured with Raman spectroscopy in cancer cells, spheroids, and canine-derived organoids","volume":"16","author":"Kothadiya","year":"2024","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"14","key":"10.1016\/j.bioactmat.2026.06.041_bib95","doi-asserted-by":"crossref","DOI":"10.1002\/advs.202309289","article-title":"Live organoid cyclic imaging","volume":"11","author":"Reynolds","year":"2024","journal-title":"Adv. Sci."},{"key":"10.1016\/j.bioactmat.2026.06.041_bib96","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2023.134809","article-title":"A buffering fluorogenic probe for real-time lysosomal pH monitoring","volume":"399","author":"Zhang","year":"2024","journal-title":"Sensor. Actuator. B Chem."},{"issue":"9","key":"10.1016\/j.bioactmat.2026.06.041_bib97","doi-asserted-by":"crossref","DOI":"10.1002\/adfm.201704598","article-title":"Nanoparticle-based fluoroionophore for analysis of potassium ion dynamics in 3D tissue models and in vivo","volume":"28","author":"M\u00fcller","year":"2018","journal-title":"Adv. Funct. Mater."},{"key":"10.1016\/j.bioactmat.2026.06.041_bib98","doi-asserted-by":"crossref","DOI":"10.1016\/j.nano.2025.102849","article-title":"Generation of fluorescent and bioluminescent induced pluripotent stem cells with their application in tracking organoid development","volume":"69","author":"Wang","year":"2025","journal-title":"Nanomed. Nanotechnol. Biol. Med."},{"issue":"11","key":"10.1016\/j.bioactmat.2026.06.041_bib99","doi-asserted-by":"crossref","first-page":"1528","DOI":"10.3390\/biomedicines9111528","article-title":"Genetically encoded fluorescent biosensors for biomedical applications","volume":"9","author":"Ovechkina","year":"2021","journal-title":"Biomedicines"},{"key":"10.1016\/j.bioactmat.2026.06.041_bib100","doi-asserted-by":"crossref","DOI":"10.1016\/j.aca.2025.344874","article-title":"Dual-organoid biosensor for monitoring cardiac conduction disturbances in vitro","volume":"1383","author":"Sv\u011br\u00e1k","year":"2026","journal-title":"Anal. Chim. Acta"},{"issue":"2","key":"10.1016\/j.bioactmat.2026.06.041_bib101","doi-asserted-by":"crossref","first-page":"2535","DOI":"10.1109\/LRA.2022.3144766","article-title":"Stiffness measurement of organoids using a wide-range force sensor probe fabricated using a quartz crystal resonator","volume":"7","author":"Watanabe","year":"2022","journal-title":"IEEE Rob. Autom. Lett."},{"key":"10.1016\/j.bioactmat.2026.06.041_bib102","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2024.116752","article-title":"Real-time electro-mechanical profiling of dynamically beating human cardiac organoids by coupling resistive skins with microelectrode arrays","volume":"267","author":"Yin","year":"2025","journal-title":"Biosens. Bioelectron."},{"issue":"1","key":"10.1016\/j.bioactmat.2026.06.041_bib103","doi-asserted-by":"crossref","first-page":"7259","DOI":"10.1038\/s41467-022-34860-y","article-title":"A soft and ultrasensitive force sensing diaphragm for probing cardiac organoids instantaneously and wirelessly","volume":"13","author":"Lyu","year":"2022","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bioactmat.2026.06.041_bib104","doi-asserted-by":"crossref","DOI":"10.1097\/HEP.0000000000001710","article-title":"Amplification of genetic and metabolic factors in alpha-1 antitrypsin deficiency","author":"Schrader","year":"2026","journal-title":"Hepatology"},{"key":"10.1016\/j.bioactmat.2026.06.041_bib105","doi-asserted-by":"crossref","DOI":"10.1016\/j.pharmthera.2021.107938","article-title":"Consideration of albumin-mediated hepatic uptake for highly protein-bound anionic drugs: bridging the gap of hepatic uptake clearance between in vitro and in vivo","volume":"229","author":"Miyauchi","year":"2022","journal-title":"Pharmacol. Ther."},{"key":"10.1016\/j.bioactmat.2026.06.041_bib106","doi-asserted-by":"crossref","DOI":"10.1016\/S0168-8278(18)31064-X","article-title":"FRI-117-Hepatic autophagy potentiates ureagenesis and its enhancement protects against acute and chronic hyperammonemia","volume":"68","author":"Soria","year":"2018","journal-title":"J. Hepatol."},{"issue":"6","key":"10.1016\/j.bioactmat.2026.06.041_bib107","doi-asserted-by":"crossref","first-page":"2050","DOI":"10.1002\/hep.30975","article-title":"Probiotic lactobacillus rhamnosus GG prevents liver fibrosis through inhibiting hepatic bile acid synthesis and enhancing bile acid excretion in mice","volume":"71","author":"Liu","year":"2020","journal-title":"Hepatology"},{"issue":"5","key":"10.1016\/j.bioactmat.2026.06.041_bib108","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1038\/ki.2010.169","article-title":"The soluble intracellular domain of megalin does not affect renal proximal tubular function in vivo","volume":"78","author":"Christ","year":"2010","journal-title":"Kidney Int."},{"issue":"5","key":"10.1016\/j.bioactmat.2026.06.041_bib109","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1002\/hep.21142","article-title":"Expression of rat renal cortical OAT1 and OAT3 in response to acute biliary obstruction","volume":"43","author":"Brandoni","year":"2006","journal-title":"Hepatology"},{"issue":"1","key":"10.1016\/j.bioactmat.2026.06.041_bib110","doi-asserted-by":"crossref","first-page":"3929","DOI":"10.1038\/s41467-020-17577-8","article-title":"A lung tropic AAV vector improves survival in a mouse model of surfactant B deficiency","volume":"11","author":"Kang","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bioactmat.2026.06.041_bib111","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1146\/annurev.physiol.66.032102.134711","article-title":"Alterations in SP-B and SP-C expression in neonatal lung disease","volume":"66","author":"Nogee","year":"2004","journal-title":"Annu. Rev. Physiol."},{"issue":"11","key":"10.1016\/j.bioactmat.2026.06.041_bib112","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1016\/S2213-2600(21)00079-5","article-title":"Airway mucin MUC5AC and MUC5B concentrations and the initiation and progression of chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort","volume":"9","author":"Radicioni","year":"2021","journal-title":"Lancet Respir. Med."},{"issue":"6","key":"10.1016\/j.bioactmat.2026.06.041_bib113","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1053\/j.gastro.2014.08.037","article-title":"Glucagon-Like Peptide-2 regulates release of chylomicrons from the intestine","volume":"147","author":"Dash","year":"2014","journal-title":"Gastroenterology"},{"issue":"1","key":"10.1016\/j.bioactmat.2026.06.041_bib114","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1038\/s41467-025-68037-0","article-title":"EatA mediated degradation of intestinal mucus is species-specific and driven by MUC2 structural features","volume":"17","author":"Trillo-Muyo","year":"2025","journal-title":"Nat. Commun."},{"issue":"1","key":"10.1016\/j.bioactmat.2026.06.041_bib115","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1038\/s41575-022-00712-9","article-title":"Mechanosensitive release of 5-HT from specialized intestinal epithelial cells","volume":"20","author":"Alcaino","year":"2023","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"issue":"1","key":"10.1016\/j.bioactmat.2026.06.041_bib116","doi-asserted-by":"crossref","first-page":"1368","DOI":"10.1038\/s41467-025-68118-0","article-title":"Brain and neural cell type proteomics reveal extracellular matrix proteins enriched in progressive multiple sclerosis","volume":"17","author":"Wang","year":"2026","journal-title":"Nat. Commun."},{"issue":"7","key":"10.1016\/j.bioactmat.2026.06.041_bib117","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1038\/s41580-023-00583-1","article-title":"Cell-extracellular matrix mechanotransduction in 3D","volume":"24","author":"Saraswathibhatla","year":"2023","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"40","key":"10.1016\/j.bioactmat.2026.06.041_bib118","doi-asserted-by":"crossref","DOI":"10.1002\/adfm.202417935","article-title":"Hypoxia-sensitive smart hydrogel biosensor for distinct mechanical and electrical signals with muscle ischemia regeneration","volume":"35","author":"Subba","year":"2025","journal-title":"Adv. Funct. Mater."},{"issue":"6565","key":"10.1016\/j.bioactmat.2026.06.041_bib119","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1126\/science.abc6229","article-title":"Bioelectric signaling and the control of cardiac cell identity in response to mechanical forces","volume":"374","author":"Fukui","year":"2021","journal-title":"Science"},{"issue":"1","key":"10.1016\/j.bioactmat.2026.06.041_bib120","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1038\/s41593-025-02111-0","article-title":"Preconfigured neuronal firing sequences in human brain organoids","volume":"29","author":"van der Molen","year":"2026","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.bioactmat.2026.06.041_bib121","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2024.136715","article-title":"Magnetic microactuator embedded electrochemical sensing platform towards on-demand sensor cleaning","volume":"424","author":"Enriquez","year":"2025","journal-title":"Sensor. Actuator. B Chem."},{"issue":"1","key":"10.1016\/j.bioactmat.2026.06.041_bib122","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1039\/D1LC00879J","article-title":"Immuno-biosensor on a chip: a self-powered microfluidic-based electrochemical biosensing platform for point-of-care quantification of proteins","volume":"22","author":"Haghayegh","year":"2022","journal-title":"Lab Chip"},{"key":"10.1016\/j.bioactmat.2026.06.041_bib123","doi-asserted-by":"crossref","DOI":"10.1016\/j.nanoen.2022.107160","article-title":"Ultra-stretchable and superhydrophobic textile-based bioelectrodes for robust self-cleaning and personal health monitoring","volume":"97","author":"Dong","year":"2022","journal-title":"Nano Energy"},{"issue":"34","key":"10.1016\/j.bioactmat.2026.06.041_bib124","doi-asserted-by":"crossref","first-page":"11916","DOI":"10.1021\/acs.analchem.2c02672","article-title":"Polymeric membrane marine sensors with a regenerable antibiofouling coating based on surface modification of a dual-functionalized magnetic composite","volume":"94","author":"Liu","year":"2022","journal-title":"Anal. Chem."},{"issue":"51","key":"10.1016\/j.bioactmat.2026.06.041_bib125","doi-asserted-by":"crossref","first-page":"28399","DOI":"10.1021\/acs.analchem.5c06964","article-title":"Fluorinated side-chain-modified peptides inspired by shark skin for antifouling electrochemical biosensing: ultrasensitive detection of CA15\u20133 in human saliva","volume":"97","author":"Yu","year":"2025","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bioactmat.2026.06.041_bib126","doi-asserted-by":"crossref","DOI":"10.1016\/j.cis.2020.102141","article-title":"Superhydrophilicity and strong salt-affinity: zwitterionic polymer grafted surfaces with significant potentials particularly in biological systems","volume":"278","author":"Li","year":"2020","journal-title":"Adv. Colloid Interface Sci."},{"key":"10.1016\/j.bioactmat.2026.06.041_bib127","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.bios.2017.10.024","article-title":"Antifouling aptasensor for the detection of adenosine triphosphate in biological media based on mixed self-assembled aptamer and zwitterionic peptide","volume":"101","author":"Wang","year":"2018","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bioactmat.2026.06.041_bib128","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.bios.2016.06.028","article-title":"Gold nanoparticles and polyethylene glycols functionalized conducting polyaniline nanowires for ultrasensitive and low fouling immunosensing of alpha-fetoprotein","volume":"86","author":"Hui","year":"2016","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bioactmat.2026.06.041_bib129","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2021.113921","article-title":"An ultrasensitive biosensor for prostate specific antigen detection in complex serum based on functional signal amplifier and designed peptides with both antifouling and recognizing capabilities","volume":"200","author":"Hui","year":"2022","journal-title":"Biosens. Bioelectron."},{"issue":"12","key":"10.1016\/j.bioactmat.2026.06.041_bib130","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.3390\/bios13121004","article-title":"Design of a facile antifouling sensor based on the synergy between an antibody and phase-transited BSA","volume":"13","author":"Wang","year":"2023","journal-title":"Biosensors"},{"issue":"38","key":"10.1016\/j.bioactmat.2026.06.041_bib131","doi-asserted-by":"crossref","first-page":"32047","DOI":"10.1021\/acsami.8b13749","article-title":"Temperature-induced denaturation of BSA protein molecules for improved surface passivation coatings","volume":"10","author":"Park","year":"2018","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"11","key":"10.1016\/j.bioactmat.2026.06.041_bib148","doi-asserted-by":"crossref","first-page":"1690","DOI":"10.1038\/s41588-022-01202-z","article-title":"Adult human kidney organoids originate from CD24+ cells and represent an advanced model for adult polycystic kidney disease","volume":"54","author":"Xu","year":"2022","journal-title":"Nat. Genet."},{"key":"10.1016\/j.bioactmat.2026.06.041_bib144","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2025.118057","article-title":"Determining the optimal transplantation window in hepatic organoids via real-time biosensing of vascularization and metabolic maturation utilizing the integrated organoid-on-a-chip platform","volume":"292","author":"Sun","year":"2026","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bioactmat.2026.06.041_bib149","doi-asserted-by":"crossref","DOI":"10.1016\/j.ccr.2024.216305","article-title":"Versatility of MXene based materials for the electrochemical detection of phenolic contaminants","volume":"525","author":"Umapathi","year":"2025","journal-title":"Coord. Chem. Rev."},{"issue":"11","key":"10.1016\/j.bioactmat.2026.06.041_bib145","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.1038\/s41551-023-01071-9","article-title":"Electro-metabolic coupling in multi-chambered vascularized human cardiac organoids","volume":"7","author":"Ghosheh","year":"2023","journal-title":"Nat. Biomed. Eng."},{"issue":"16","key":"10.1016\/j.bioactmat.2026.06.041_bib146","doi-asserted-by":"crossref","first-page":"6481","DOI":"10.1021\/acs.nanolett.5c00069","article-title":"Soft 3D bioelectrodes for intraorganoid signal monitoring in cardiac models","volume":"25","author":"Park","year":"2025","journal-title":"Nano Lett."},{"issue":"4","key":"10.1016\/j.bioactmat.2026.06.041_bib132","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/j.stem.2022.03.012","article-title":"Progress in multicellular human cardiac organoids for clinical applications","volume":"29","author":"Kim","year":"2022","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.bioactmat.2026.06.041_bib133","doi-asserted-by":"crossref","unstructured":"N. Gjorevski, M. Nikolaev, T.E. Brown, O. Mitrofanova, N. Brandenberg, F.W. DelRio, F.M. Yavitt, P. Liberali, K.S. Anseth, M.P. Lutolf, Tissue geometry drives deterministic organoid patterning, Science 375(6576) eaaw9021.","DOI":"10.1126\/science.aaw9021"},{"issue":"3","key":"10.1016\/j.bioactmat.2026.06.041_bib134","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1136\/gutjnl-2016-312865","article-title":"Building pancreatic organoids to aid drug development","volume":"66","author":"Wills","year":"2017","journal-title":"Gut"},{"issue":"6","key":"10.1016\/j.bioactmat.2026.06.041_bib135","doi-asserted-by":"crossref","first-page":"1884","DOI":"10.1038\/s41596-019-0168-0","article-title":"Isolation and propagation of primary human cholangiocyte organoids for the generation of bioengineered biliary tissue","volume":"14","author":"Tysoe","year":"2019","journal-title":"Nat. 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