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Colloid Interface Sci."},{"key":"10.1016\/j.bioactmat.2026.06.042_bib196","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/j.biomaterials.2015.08.045","article-title":"Synthesis, properties, and biomedical applications of gelatin methacryloyl (GelMA) hydrogels","volume":"73","author":"Yue","year":"2015","journal-title":"Biomaterials"},{"key":"10.1016\/j.bioactmat.2026.06.042_bib197","doi-asserted-by":"crossref","first-page":"6955","DOI":"10.2147\/IJN.S436350","article-title":"ApoSEVs-Mediated Modulation of Versatile Target Cells Promotes Diabetic Wound Healing: Unveiling a Promising Strategy","volume":"18","author":"Yang","year":"2023","journal-title":"Int. J. 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Mater."},{"issue":"30","key":"10.1016\/j.bioactmat.2026.06.042_bib298","article-title":"Four\u2010Arm Polymer\u2010Guided Formation of Curcumin\u2010Loaded Flower\u2010Like Porous Microspheres as Injectable Cell Carriers for Diabetic Wound Healing","volume":"12","author":"Yuan","year":"2023","journal-title":"Adv. Healthcare Mater."},{"issue":"7","key":"10.1016\/j.bioactmat.2026.06.042_bib299","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1038\/nmat4294","article-title":"Accelerated wound healing by injectable microporous gel scaffolds assembled from annealed building blocks","volume":"14","author":"Griffin","year":"2015","journal-title":"Nat. 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Wound J."},{"issue":"22","key":"10.1016\/j.bioactmat.2026.06.042_bib304","doi-asserted-by":"crossref","first-page":"28147","DOI":"10.1021\/acsami.4c03655","article-title":"Electrospray Nano-Micro Composite Sodium Alginate Microspheres with Shape-Adaptive, Antibacterial, and Angiogenic Abilities for Infected Wound Healing","volume":"16","author":"Song","year":"2024","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.bioactmat.2026.06.042_bib305","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.msec.2018.04.009","article-title":"Tunable sequential drug delivery system based on chitosan\/hyaluronic acid hydrogels and PLGA microspheres for management of non-healing infected wounds","volume":"89","author":"Huang","year":"2018","journal-title":"Mater. Sci. Eng. 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Sci."},{"issue":"26","key":"10.1016\/j.bioactmat.2026.06.042_bib308","doi-asserted-by":"crossref","DOI":"10.1002\/adfm.202315590","article-title":"Acupoint Therapy with Injectable, Pro\u2010Healing Stem Cell\u2010Loaded Hydrogel Microspheres Promotes Skin Wound Healing","volume":"34","author":"Yan","year":"2024","journal-title":"Adv. Funct. Mater."},{"issue":"7","key":"10.1016\/j.bioactmat.2026.06.042_bib309","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1089\/wound.2022.0034","article-title":"Gelatin Microspheres Loaded with Wharton's Jelly Mesenchymal Stem Cells Promote Acute Full-Thickness Skin Wound Healing and Regeneration in Mice","volume":"12","author":"Jiao","year":"2023","journal-title":"Adv. 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Sci."},{"issue":"8","key":"10.1016\/j.bioactmat.2026.06.042_bib313","doi-asserted-by":"crossref","DOI":"10.3390\/ijms24087319","article-title":"Application of Biomedical Microspheres in Wound Healing","volume":"24","author":"Yang","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.bioactmat.2026.06.042_bib314","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2022.141111","article-title":"Bioinspired hierarchical delivery system with macrophage-like nanovesicles encapsulation for diabetic wound healing","volume":"456","author":"Che","year":"2023","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.bioactmat.2026.06.042_bib315","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2023.134396","article-title":"On-demand delivery of therapeutic extracellular vesicles by encapsulating in monodispersed photodegradable hydrogel microparticles using a droplet microfluidic device","volume":"394","author":"Kim","year":"2023","journal-title":"Sensor Actuat. 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