{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,30]],"date-time":"2026-08-30T09:15:15Z","timestamp":1788081315795,"version":"build-2784847793"},"reference-count":52,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T00:00:00Z","timestamp":1784592000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32171336"],"award-info":[{"award-number":["32171336"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004731","name":"Natural Science Foundation of Zhejiang Province","doi-asserted-by":"publisher","award":["LHDMY24H300002"],"award-info":[{"award-number":["LHDMY24H300002"]}],"id":[{"id":"10.13039\/501100004731","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioactive Materials"],"published-print":{"date-parts":[[2027,1]]},"DOI":"10.1016\/j.bioactmat.2026.07.037","type":"journal-article","created":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T02:40:43Z","timestamp":1787280043000},"page":"656-675","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Reversing zinc dyshomeostasis and oxidative stress: A metallothionein 1-activating MXene\/Zn2+ triple-action nanotherapeutic strategy for chronic non-bacterial prostatitis"],"prefix":"10.1016","volume":"67","author":[{"given":"Kailai","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuchen","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanyao","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunhe","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiangchuan","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanchao","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinpeng","family":"Wen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhengye","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keke","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiang","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"He","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6549-3203","authenticated-orcid":false,"given":"Ke","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bioactmat.2026.07.037_bib1","doi-asserted-by":"crossref","DOI":"10.1136\/bmj-2023-073908","article-title":"Chronic prostatitis (chronic pelvic pain syndrome)","volume":"383","author":"Healy","year":"2023","journal-title":"BMJ"},{"issue":"2","key":"10.1016\/j.bioactmat.2026.07.037_bib2","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1016\/j.juro.2009.04.011","article-title":"The prevalence of prostatitis-like symptoms in China","volume":"182","author":"Liang","year":"2009","journal-title":"J. Urol."},{"key":"10.1016\/j.bioactmat.2026.07.037_bib3","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2022.112830","article-title":"Jiedu Huoxue decoction improves chronic abacterial prostatitis\/chronic pelvic pain syndrome through activating Wnt\/GSK\u03b2\/\u03b2-catenin signaling pathway and alleviating apoptosis","volume":"149","author":"Yi","year":"2022","journal-title":"Biomed. Pharmacother."},{"issue":"6","key":"10.1016\/j.bioactmat.2026.07.037_bib4","doi-asserted-by":"crossref","first-page":"1454","DOI":"10.1016\/j.urology.2015.03.007","article-title":"Animal models of urologic chronic pelvic pain syndromes: findings from the multidisciplinary approach to the study of chronic pelvic pain research network","volume":"85","author":"Lai","year":"2015","journal-title":"Urology"},{"issue":"10","key":"10.1016\/j.bioactmat.2026.07.037_bib5","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1016\/j.mayocp.2016.08.011","article-title":"Anorectal and pelvic pain","volume":"91","author":"Bharucha","year":"2016","journal-title":"Mayo Clin. Proc."},{"issue":"4","key":"10.1016\/j.bioactmat.2026.07.037_bib6","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1111\/bju.14988","article-title":"Pharmacological interventions for treating chronic prostatitis\/chronic pelvic pain syndrome: a Cochrane systematic review","volume":"125","author":"Franco","year":"2020","journal-title":"BJU Int."},{"issue":"2","key":"10.1016\/j.bioactmat.2026.07.037_bib7","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/S0090-4295(99)00205-8","volume":"54","author":"Nickel","year":"1999","journal-title":"Urology"},{"issue":"3","key":"10.1016\/j.bioactmat.2026.07.037_bib8","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1038\/nrurol.2010.4","article-title":"New treatments for chronic prostatitis\/chronic pelvic pain syndrome","volume":"7","author":"Strauss","year":"2010","journal-title":"Nat. Rev. Urol."},{"key":"10.1016\/j.bioactmat.2026.07.037_bib9","doi-asserted-by":"crossref","DOI":"10.3390\/ijms21207796","article-title":"The role of zinc in Male fertility","author":"Allouche-Fitoussi","year":"2020","journal-title":"Int. J. Mol. Sci."},{"issue":"4","key":"10.1016\/j.bioactmat.2026.07.037_bib10","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0280821","article-title":"Comparative analysis of efficacy of different combination therapies of \u03b1-receptor blockers and traditional Chinese medicine external therapy in the treatment of chronic prostatitis\/chronic pelvic pain syndrome: bayesian network meta-analysis","volume":"18","author":"Zhang","year":"2023","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.bioactmat.2026.07.037_bib11","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1186\/1471-2334-8-12","article-title":"Acute bacterial prostatitis: heterogeneity in diagnostic criteria and management. Retrospective multicentric analysis of 371 patients diagnosed with acute prostatitis","volume":"8","author":"Etienne","year":"2008","journal-title":"BMC Infect. Dis."},{"issue":"10","key":"10.1016\/j.bioactmat.2026.07.037_bib12","doi-asserted-by":"crossref","first-page":"813","DOI":"10.56434\/j.arch.esp.urol.20227510.119","article-title":"Clinical observations of percutaneous tibial nerve stimulation combined with sacral nerve root magnetic stimulation for the treatment of Male chronic pelvic pain and chronic prostatitis","volume":"75","author":"Sihui","year":"2022","journal-title":"Arch. Esp. Urol."},{"issue":"5","key":"10.1016\/j.bioactmat.2026.07.037_bib13","doi-asserted-by":"crossref","first-page":"1593","DOI":"10.1111\/andr.13027","article-title":"Li-ESWT treatment reduces inflammation, oxidative stress, and pain via the PI3K\/AKT\/FOXO1 pathway in autoimmune prostatitis rat models","volume":"9","author":"Feng","year":"2021","journal-title":"Andrology"},{"key":"10.1016\/j.bioactmat.2026.07.037_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2023.155249","article-title":"Astaxanthin alleviates chronic prostatitis\/chronic pelvic pain syndrome by increasing colonization of Akkermansia muciniphila in the intestine","volume":"123","author":"Liu","year":"2024","journal-title":"Phytomedicine"},{"issue":"27","key":"10.1016\/j.bioactmat.2026.07.037_bib15","doi-asserted-by":"crossref","first-page":"4249","DOI":"10.2174\/0109298673279207231228070533","article-title":"Current understanding of androgen signaling in prostatitis and its treatment: a review","volume":"31","author":"Marisa","year":"2024","journal-title":"Curr. Med. Chem."},{"issue":"1","key":"10.1016\/j.bioactmat.2026.07.037_bib16","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.jtemb.2006.01.006","article-title":"Zinc requirements and the risks and benefits of zinc supplementation","volume":"20","author":"Maret","year":"2006","journal-title":"J. Trace Elem. Med. Biol."},{"key":"10.1016\/j.bioactmat.2026.07.037_bib17","series-title":"Post\u0119py Higieny I Medycyny Do\u015bwiadczalnej 71","article-title":"Role of copper in the process of spermatogenesis","author":"Og\u00f3rek","year":"2017"},{"key":"10.1016\/j.bioactmat.2026.07.037_bib18","doi-asserted-by":"crossref","DOI":"10.3390\/biomedicines10123206","article-title":"Zinc in prostate health and disease: a mini review","author":"Karunasinghe","year":"2022","journal-title":"Biomedicines"},{"issue":"6","key":"10.1016\/j.bioactmat.2026.07.037_bib19","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1016\/S0924-8579(02)00115-2","article-title":"Antibacterial effect of intraprostatic zinc injection in a rat model of chronic bacterial prostatitis","volume":"19","author":"Cho","year":"2002","journal-title":"Int. J. Antimicrob. Agents"},{"key":"10.1016\/j.bioactmat.2026.07.037_bib20","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1185\/03007995.2015.1072707","article-title":"The effect of chronic prostatitis on zinc concentration of prostatic fluid and seminal plasma: a systematic review and meta-analysis","volume":"31","author":"Cui","year":"2015","journal-title":"Curr. Med. Res. Opin."},{"key":"10.1016\/j.bioactmat.2026.07.037_bib21","first-page":"259","article-title":"The efficacy of zinc for treatment of chronic prostatitis","volume":"45","author":"Goodarzi","year":"2013","journal-title":"Acta Medica Indonesiana"},{"issue":"2","key":"10.1016\/j.bioactmat.2026.07.037_bib22","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/0090-4295(76)90305-8","article-title":"Prostatic antibacterial factor identity and significance","volume":"7","author":"Fair","year":"1976","journal-title":"Urology"},{"issue":"1","key":"10.1016\/j.bioactmat.2026.07.037_bib23","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1186\/s12894-024-01656-9","article-title":"Comparative study of trace metal concentration in the diagnosis of category III prostatitis","volume":"24","author":"Lin","year":"2024","journal-title":"BMC Urol."},{"key":"10.1016\/j.bioactmat.2026.07.037_bib24","doi-asserted-by":"crossref","DOI":"10.3390\/ijms22157854","article-title":"Chronic prostatitis\/chronic pelvic pain syndrome leads to impaired semen parameters, increased sperm DNA fragmentation and unfavorable changes of sperm protamine mRNA ratio","author":"Berg","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.bioactmat.2026.07.037_bib25","series-title":"Influence of Adding Zinc Arginyle-Glycinate to Improve Efficacy of Bioregulatory Peptides of The Prostate Gland in Treatment of Patients with Impaired Sperm Parameters","first-page":"108","author":"Rybalov","year":"2022"},{"issue":"1","key":"10.1016\/j.bioactmat.2026.07.037_bib26","doi-asserted-by":"crossref","first-page":"51","DOI":"10.3892\/etm.2017.4448","article-title":"The mediation of interleukin-17 and chemokine ligand 2 in pelvic pain of experimental autoimmune prostatitis","volume":"14","author":"Liu","year":"2017","journal-title":"Exp. Ther. Med."},{"key":"10.1016\/j.bioactmat.2026.07.037_bib27","article-title":"Influence of experimental autoimmune prostatitis on sexual function and the anti-inflammatory efficacy of celecoxib in a rat model","volume":"11","author":"Zhang","year":"2020","journal-title":"Front. Immunol."},{"key":"10.1016\/j.bioactmat.2026.07.037_bib28","article-title":"Obacunone alleviates chronic pelvic pain and pro-inflammatory depolarization of macrophage induced by experimental autoimmune prostatitis in mice","volume":"36","author":"Wang","year":"2023","journal-title":"Biochem. Biophys. Rep."},{"issue":"11","key":"10.1016\/j.bioactmat.2026.07.037_bib29","doi-asserted-by":"crossref","first-page":"6383","DOI":"10.1021\/jacs.2c13578","article-title":"Structural role of cadmium and zinc in metallothionein oxidation by hydrogen peroxide: the resilience of metal\u2013thiolate clusters","volume":"145","author":"Korkola","year":"2023","journal-title":"J. Am. Chem. Soc."},{"issue":"1","key":"10.1016\/j.bioactmat.2026.07.037_bib30","doi-asserted-by":"crossref","DOI":"10.1002\/eji.202250019","article-title":"Pleural CD14+ monocytes\/macrophages of healthy adolescents show a high expression of metallothionein family genes","volume":"53","author":"Schukfeh","year":"2023","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.bioactmat.2026.07.037_bib31","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2025.123234","article-title":"MXene-loaded multifunctional nanoparticles with on-demand controlled antimicrobial and antioxidant capacity for multi-modal treating bacterial prostatitis","volume":"320","author":"Liu","year":"2025","journal-title":"Biomaterials"},{"issue":"10","key":"10.1016\/j.bioactmat.2026.07.037_bib32","doi-asserted-by":"crossref","DOI":"10.1093\/mtomcs\/mfae041","article-title":"Thermodynamic origin of the affinity, selectivity, and domain specificity of metallothionein for essential and toxic metal ions","volume":"16","author":"Quinn","year":"2024","journal-title":"Metallomics"},{"issue":"1","key":"10.1016\/j.bioactmat.2026.07.037_bib33","doi-asserted-by":"crossref","first-page":"3738","DOI":"10.1038\/s41467-025-58987-w","article-title":"A dynamically phase-adaptive regulating hydrogel promotes ultrafast anti-fibrotic wound healing","volume":"16","author":"Zhang","year":"2025","journal-title":"Nat. Commun."},{"issue":"4","key":"10.1016\/j.bioactmat.2026.07.037_bib34","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1248\/bpb.35.588","article-title":"In Vitro study on the transport of zinc across intestinal epithelial cells using Caco-2 monolayers and isolated rat intestinal membranes","volume":"35","author":"Yasuno","year":"2012","journal-title":"Biol. Pharm. Bull."},{"key":"10.1016\/j.bioactmat.2026.07.037_bib35","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.739918","article-title":"Metallothionein 1: a new spotlight on inflammatory diseases","volume":"12","author":"Dai","year":"2021","journal-title":"Front. Immunol."},{"issue":"D1","key":"10.1016\/j.bioactmat.2026.07.037_bib36","doi-asserted-by":"crossref","first-page":"D1516","DOI":"10.1093\/nar\/gkae1059","article-title":"PubChem 2025 update","volume":"53","author":"Kim","year":"2025","journal-title":"Nucleic Acids Res."},{"issue":"19","key":"10.1016\/j.bioactmat.2026.07.037_bib37","doi-asserted-by":"crossref","DOI":"10.1063\/5.0007045","article-title":"CP2K: an electronic structure and molecular dynamics software package - quickstep: efficient and accurate electronic structure calculations","volume":"152","author":"K\u00fchne","year":"2020","journal-title":"J. Chem. Phys."},{"key":"10.1016\/j.bioactmat.2026.07.037_bib38","author":"Lu"},{"key":"10.1016\/j.bioactmat.2026.07.037_bib39","unstructured":"E.F. Valeev, Libint: a Library for the Evaluation of Molecular Integrals of many-body Operators over Gaussian Functions, (Version 2.10.2)."},{"issue":"10","key":"10.1016\/j.bioactmat.2026.07.037_bib40","doi-asserted-by":"crossref","first-page":"2272","DOI":"10.1016\/j.cpc.2012.05.007","article-title":"Libxc: a library of exchange and correlation functionals for density functional theory","volume":"183","author":"Marques","year":"2012","journal-title":"Comput. Phys. Commun."},{"issue":"11","key":"10.1016\/j.bioactmat.2026.07.037_bib41","doi-asserted-by":"crossref","DOI":"10.1063\/5.0167763","article-title":"Reproducibility of density functional approximations: how new functionals should be reported","volume":"159","author":"Lehtola","year":"2023","journal-title":"J. Chem. Phys."},{"key":"10.1016\/j.bioactmat.2026.07.037_bib42","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.softx.2017.11.002","article-title":"Recent developments in libxc \u2014 a comprehensive library of functionals for density functional theory","volume":"7","author":"Lehtola","year":"2018","journal-title":"SoftwareX"},{"issue":"9","key":"10.1016\/j.bioactmat.2026.07.037_bib43","doi-asserted-by":"crossref","first-page":"922","DOI":"10.1002\/jcc.26139","article-title":"Effect of the solute cavity on the solvation energy and its derivatives within the framework of the Gaussian charge scheme","volume":"41","author":"Garcia-Rat\u00e9s","year":"2020","journal-title":"J. Comput. Chem."},{"issue":"20","key":"10.1016\/j.bioactmat.2026.07.037_bib44","doi-asserted-by":"crossref","first-page":"1816","DOI":"10.1002\/jcc.25833","article-title":"Efficient implementation of the analytical second derivatives of hartree\u2013fock and hybrid DFT energies within the framework of the conductor-like polarizable continuum model","volume":"40","author":"Garcia-Rat\u00e9s","year":"2019","journal-title":"J. Comput. Chem."},{"issue":"2","key":"10.1016\/j.bioactmat.2026.07.037_bib45","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1021\/acs.jctc.6b01041","article-title":"Automatic generation of auxiliary basis sets","volume":"13","author":"Stoychev","year":"2017","journal-title":"J. Chem. Theor. Comput."},{"issue":"1","key":"10.1016\/j.bioactmat.2026.07.037_bib46","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.chemphys.2008.10.036","article-title":"Efficient, approximate and parallel Hartree\u2013Fock and hybrid DFT calculations. A \u2018chain-of-spheres\u2019 algorithm for the Hartree\u2013Fock exchange","volume":"356","author":"Neese","year":"2009","journal-title":"Chem. Phys."},{"issue":"14","key":"10.1016\/j.bioactmat.2026.07.037_bib47","doi-asserted-by":"crossref","first-page":"1740","DOI":"10.1002\/jcc.10318","article-title":"An improvement of the resolution of the identity approximation for the formation of the Coulomb matrix","volume":"24","author":"Neese","year":"2003","journal-title":"J. Comput. Chem."},{"issue":"5","key":"10.1016\/j.bioactmat.2026.07.037_bib48","doi-asserted-by":"crossref","DOI":"10.1002\/wcms.1606","article-title":"Software update: the ORCA program system\u2014Version 5.0","volume":"12","author":"Neese","year":"2022","journal-title":"WIREs Comput. Mol. Sci."},{"issue":"1","key":"10.1016\/j.bioactmat.2026.07.037_bib49","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1002\/wcms.81","article-title":"The ORCA program system","volume":"2","author":"Neese","year":"2012","journal-title":"WIREs Comput. Mol. Sci."},{"issue":"5","key":"10.1016\/j.bioactmat.2026.07.037_bib50","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1002\/jcc.22885","article-title":"Multiwfn: a multifunctional wavefunction analyzer","volume":"33","author":"Lu","year":"2012","journal-title":"J. Comput. Chem."},{"issue":"8","key":"10.1016\/j.bioactmat.2026.07.037_bib51","doi-asserted-by":"crossref","DOI":"10.1063\/5.0216272","article-title":"A comprehensive electron wavefunction analysis toolbox for chemists, Multiwfn","volume":"161","author":"Lu","year":"2024","journal-title":"J. Chem. Phys."},{"key":"10.1016\/j.bioactmat.2026.07.037_bib52","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.softx.2015.06.001","article-title":"GROMACS: high performance molecular simulations through multi-level parallelism from laptops to supercomputers","volume":"1\u20132","author":"Abraham","year":"2015","journal-title":"SoftwareX"}],"container-title":["Bioactive Materials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2452199X26004342?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2452199X26004342?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,30]],"date-time":"2026-08-30T08:52:48Z","timestamp":1788079968000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2452199X26004342"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2027,1]]},"references-count":52,"alternative-id":["S2452199X26004342"],"URL":"https:\/\/doi.org\/10.1016\/j.bioactmat.2026.07.037","relation":{},"ISSN":["2452-199X"],"issn-type":[{"value":"2452-199X","type":"print"}],"subject":[],"published":{"date-parts":[[2027,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Reversing zinc dyshomeostasis and oxidative stress: A metallothionein 1-activating MXene\/Zn2+ triple-action nanotherapeutic strategy for chronic non-bacterial prostatitis","name":"articletitle","label":"Article Title"},{"value":"Bioactive Materials","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bioactmat.2026.07.037","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Publishing services by Elsevier B.V. on behalf of KeAi Communications Co. Ltd.","name":"copyright","label":"Copyright"}]}}