{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T21:04:15Z","timestamp":1790283855019,"version":"4.1.0"},"reference-count":68,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2027,2,1]],"date-time":"2027-02-01T00:00:00Z","timestamp":1801440000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2027,2,1]],"date-time":"2027-02-01T00:00:00Z","timestamp":1801440000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T00:00:00Z","timestamp":1789516800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100011400","name":"Nanjing University State Key Laboratory of Analytical Chemistry for Life Science","doi-asserted-by":"publisher","award":["SKLACLS2514"],"award-info":[{"award-number":["SKLACLS2514"]}],"id":[{"id":"10.13039\/501100011400","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82061148012"],"award-info":[{"award-number":["82061148012"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82027806"],"award-info":[{"award-number":["82027806"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["U25A20566"],"award-info":[{"award-number":["U25A20566"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["92461308"],"award-info":[{"award-number":["92461308"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioactive Materials"],"published-print":{"date-parts":[[2027,2]]},"DOI":"10.1016\/j.bioactmat.2026.09.021","type":"journal-article","created":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T17:38:42Z","timestamp":1790012322000},"page":"931-950","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Engineered probiotics couple photothermal cuproptosis with biomechanical disruption and immune activation"],"prefix":"10.1016","volume":"68","author":[{"given":"Xiaoyang","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaohui","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ke","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baijiang","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nan","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuemei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bioactmat.2026.09.021_bib1","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1038\/s41378-024-00743-z","article-title":"Bacterial nanotechnology as a paradigm in targeted cancer therapeutic delivery and immunotherapy","volume":"10","author":"Gholami","year":"2024","journal-title":"Microsyst. Nanoeng."},{"key":"10.1016\/j.bioactmat.2026.09.021_bib2","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1038\/s42254-024-00707-2","article-title":"Mechanical properties of human tumour tissues and their implications for cancer development","volume":"6","author":"Massey","year":"2024","journal-title":"Nat. Rev. Phys."},{"key":"10.1016\/j.bioactmat.2026.09.021_bib3","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1038\/s44222-025-00391-6","article-title":"Mechanomedicine","volume":"4","author":"Liu","year":"2026","journal-title":"Nat. Rev. Bioeng."},{"key":"10.1016\/j.bioactmat.2026.09.021_bib4","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1038\/s41392-023-01536-y","article-title":"Nanomedicine in cancer therapy","volume":"8","author":"Fan","year":"2023","journal-title":"Signal Transduct. Targeted Ther."},{"key":"10.1016\/j.bioactmat.2026.09.021_bib5","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1038\/s41392-023-01642-x","article-title":"Smart nanoparticles for cancer therapy","volume":"8","author":"Sun","year":"2023","journal-title":"Signal Transduct. Targeted Ther."},{"key":"10.1016\/j.bioactmat.2026.09.021_bib6","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1038\/s41568-022-00496-9","article-title":"Cancer nanomedicine","volume":"22","author":"Bhatia","year":"2022","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.bioactmat.2026.09.021_bib7","doi-asserted-by":"crossref","DOI":"10.1016\/j.chempr.2025.102706","article-title":"Cancer nanomedicine: concepts, promises, and challenges","volume":"11","author":"Zhu","year":"2025","journal-title":"Chem"},{"key":"10.1016\/j.bioactmat.2026.09.021_bib8","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1038\/s41586-024-08033-4","article-title":"Probiotic neoantigen delivery vectors for precision cancer immunotherapy","volume":"635","author":"Redenti","year":"2024","journal-title":"Nature"},{"key":"10.1016\/j.bioactmat.2026.09.021_bib9","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1186\/s12951-025-03968-w","article-title":"Bacteria-powered LA@CaDGP biomotor: a multi-modal weapon integrating calcium overload, chemotherapy, and starvation for breast cancer therapy","volume":"24","author":"Huang","year":"2026","journal-title":"J. Nanobiotechnol."},{"key":"10.1016\/j.bioactmat.2026.09.021_bib10","article-title":"Sustained nitric oxide production by engineered E. coli remodels the tumor microenvironment and potentiates immunotherapy","author":"Xu","year":"2026","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.bioactmat.2026.09.021_bib11","article-title":"Functionalized microalgae as emerging composite bioproducts for biomedical applications: design, fabrication and prospects","volume":"11","author":"Gao","year":"2026","journal-title":"J. Bioresour. Bioprod."},{"key":"10.1016\/j.bioactmat.2026.09.021_bib12","article-title":"Harnessing bacteria for tumor therapy: current advances and challenges","volume":"35","author":"Guo","year":"2024","journal-title":"Chin. Chem. Lett."},{"key":"10.1016\/j.bioactmat.2026.09.021_bib13","doi-asserted-by":"crossref","first-page":"5167","DOI":"10.1016\/j.apsb.2025.07.028","article-title":"Progress and challenges of functionalized bacterial encapsulation: a novel biotechnology for next-generation biotherapeutics","volume":"15","author":"Zhang","year":"2025","journal-title":"Acta Pharm. Sin. B"},{"key":"10.1016\/j.bioactmat.2026.09.021_bib14","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1038\/s41467-024-44776-4","article-title":"Engineering tumor-colonizing E. coli Nissle 1917 for detection and treatment of colorectal neoplasia","volume":"15","author":"Gurbatri","year":"2024","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bioactmat.2026.09.021_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.biotechadv.2023.108202","article-title":"Engineering Escherichia coli Nissle 1917 as a microbial chassis for therapeutic and industrial applications","volume":"67","author":"Yu","year":"2023","journal-title":"Biotechnol. Adv."},{"key":"10.1016\/j.bioactmat.2026.09.021_bib16","doi-asserted-by":"crossref","first-page":"2431","DOI":"10.1016\/j.apsb.2025.03.021","article-title":"Modified probiotics and the related combinatorial therapeutics","volume":"15","author":"Zhao","year":"2025","journal-title":"Acta Pharm. Sin. B"},{"key":"10.1016\/j.bioactmat.2026.09.021_bib17","doi-asserted-by":"crossref","DOI":"10.1016\/j.cis.2025.103631","article-title":"Physical and chemical approaches to tailor 2D coating\/substrate adhesion - experimental and theoretical insights","volume":"345","author":"Rosenkranz","year":"2025","journal-title":"Adv. Colloid Interface Sci."},{"key":"10.1016\/j.bioactmat.2026.09.021_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.pmatsci.2023.101125","article-title":"Recent advances and strategies for high-performance coatings","volume":"136","author":"Ou","year":"2023","journal-title":"Prog. Mater. Sci."},{"key":"10.1016\/j.bioactmat.2026.09.021_bib19","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1016\/j.actbio.2022.12.072","article-title":"Gold nanobipyramid@copper sulfide nanotheranostics for image-guided NIR-II photo\/chemodynamic cancer therapy with enhanced immune response","volume":"158","author":"Chen","year":"2023","journal-title":"Acta Biomater."},{"key":"10.1016\/j.bioactmat.2026.09.021_bib20","article-title":"Triple-functional CuxAu61-x nanoclusters with NIR-II photoluminescence, photothermal and photodynamic properties and their bio-application","volume":"12","author":"Xu","year":"2025","journal-title":"Adv. Sci."},{"key":"10.1016\/j.bioactmat.2026.09.021_bib21","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1038\/s41392-025-02192-0","article-title":"The molecular mechanism and therapeutic landscape of copper and cuproptosis in cancer","volume":"10","author":"Guo","year":"2025","journal-title":"Signal Transduct. Targeted Ther."},{"key":"10.1016\/j.bioactmat.2026.09.021_bib22","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1038\/s41423-026-01387-x","article-title":"Tackling cuproptosis: from metabolic rewiring to therapeutic exploitation in cancer","volume":"23","author":"Hao","year":"2026","journal-title":"Cell. Mol. Immunol."},{"key":"10.1016\/j.bioactmat.2026.09.021_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.cclet.2023.108765","article-title":"Combination losartan with hyaluronic acid modified diethyldithiocarbamate loaded hollow copper sulfide nanoparticles for the treatment of breast cancer and metastasis","volume":"35","author":"Hu","year":"2024","journal-title":"Chin. Chem. Lett."},{"key":"10.1016\/j.bioactmat.2026.09.021_bib24","doi-asserted-by":"crossref","first-page":"1810","DOI":"10.1038\/s41596-024-01115-7","article-title":"Photothermal nanofiber-mediated photoporation for gentle and efficient intracellular delivery of macromolecules","volume":"20","author":"Miao","year":"2025","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.bioactmat.2026.09.021_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.jphotochemrev.2026.100736","article-title":"Photothermal nanomaterials for biomedical therapy and diagnosis: from photothermal conversion mechanisms to clinical translation","volume":"66","author":"Shi","year":"2026","journal-title":"J. Photochem. Photobiol. C Photochem. Rev."},{"key":"10.1016\/j.bioactmat.2026.09.021_bib26","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1038\/s41467-023-44664-3","article-title":"Dual-plasmonic Au@Cu7S4 yolk@shell nanocrystals for photocatalytic hydrogen production across visible to near infrared spectral region","volume":"15","author":"Tsao","year":"2024","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bioactmat.2026.09.021_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2024.150271","article-title":"Facile construction of polycation\/Au@CuS nanohybrids for synergistic gene\/photothermal therapy","volume":"486","author":"Zheng","year":"2024","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.bioactmat.2026.09.021_bib28","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1038\/s41419-024-06697-4","article-title":"Modulating extracellular matrix stiffness: a strategic approach to boost cancer immunotherapy","volume":"15","author":"Mai","year":"2024","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.bioactmat.2026.09.021_bib29","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1038\/s42003-022-04320-w","article-title":"Biomechanical, biophysical and biochemical modulators of cytoskeletal remodelling and emergent stem cell lineage commitment","volume":"6","author":"Putra","year":"2023","journal-title":"Commun. Biol."},{"key":"10.1016\/j.bioactmat.2026.09.021_bib30","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1186\/s40164-025-00647-2","article-title":"Extracellular matrix stiffness: mechanisms in tumor progression and therapeutic potential in cancer","volume":"14","author":"Zhang","year":"2025","journal-title":"Exp. Hematol. Oncol."},{"key":"10.1016\/j.bioactmat.2026.09.021_bib31","first-page":"14","article-title":"Macroporous scaffolds based on biomass polymers and their applications in wound healing","volume":"10","author":"Gao","year":"2025","journal-title":"J. Bioresour. Bioprod."},{"key":"10.1016\/j.bioactmat.2026.09.021_bib32","first-page":"576","article-title":"Sustainable anti-fibrillation and multifunction enhancement of lyocell fabric via electrostatic adsorption and discontinuous membrane formation","volume":"10","author":"Wang","year":"2025","journal-title":"J. Bioresour. Bioprod."},{"key":"10.1016\/j.bioactmat.2026.09.021_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.cclet.2025.111588","article-title":"Manipulating extracellular matrix to enhance intratumor drug delivery for nanomaterial-based photothermal therapy","volume":"36","author":"Zhang","year":"2025","journal-title":"Chin. Chem. Lett."},{"key":"10.1016\/j.bioactmat.2026.09.021_bib34","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1007\/s12668-025-02180-2","article-title":"Polydopamine-based nanomaterials for multifunctional cancer therapy","volume":"15","author":"Thirumalai","year":"2025","journal-title":"BioNanoScience"},{"key":"10.1016\/j.bioactmat.2026.09.021_bib35","doi-asserted-by":"crossref","first-page":"16113","DOI":"10.1021\/jacs.1c06652","article-title":"Plasmonic aupt@cus heterostructure with enhanced synergistic efficacy for radiophotothermal therapy","volume":"143","author":"Cai","year":"2021","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.bioactmat.2026.09.021_bib36","doi-asserted-by":"crossref","DOI":"10.1016\/j.cis.2022.102778","article-title":"A review of zeta potential measurements using electroacoustics","volume":"309","author":"Mohammadi-Jam","year":"2022","journal-title":"Adv. Colloid Interface Sci."},{"key":"10.1016\/j.bioactmat.2026.09.021_bib37","doi-asserted-by":"crossref","first-page":"2012","DOI":"10.1021\/la0476332","article-title":"Synthesis of branched gold nanocrystals by a seeding growth approach","volume":"21","author":"Kuo","year":"2005","journal-title":"Langmuir : the ACS journal of surfaces and colloids"},{"key":"10.1016\/j.bioactmat.2026.09.021_bib38","article-title":"Copper sulfide engineered covalent organic frameworks for pH-responsive chemo\/photothermal\/chemodynamic synergistic therapy against cancer","volume":"451","author":"Wang","year":"2023","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.bioactmat.2026.09.021_bib39","doi-asserted-by":"crossref","first-page":"17630","DOI":"10.1021\/ja409754v","article-title":"Copper sulfide nanocrystals with tunable composition by reduction of covellite nanocrystals with Cu+ ions","volume":"135","author":"Xie","year":"2013","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.bioactmat.2026.09.021_bib40","doi-asserted-by":"crossref","DOI":"10.1016\/j.cclet.2023.108285","article-title":"Engineering sulfur vacancies for boosting electrocatalytic reactions","volume":"34","author":"Chu","year":"2023","journal-title":"Chin. Chem. Lett."},{"key":"10.1016\/j.bioactmat.2026.09.021_bib41","doi-asserted-by":"crossref","DOI":"10.1002\/smll.201700867","article-title":"Localized defects on copper sulfide surface for enhanced plasmon resonance and water splitting","volume":"13","author":"Ren","year":"2017","journal-title":"Small"},{"key":"10.1016\/j.bioactmat.2026.09.021_bib42","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1002\/sia.6239","article-title":"Advanced analysis of copper X-ray photoelectron spectra","volume":"49","author":"Biesinger","year":"2017","journal-title":"Surf. Interface Anal."},{"key":"10.1016\/j.bioactmat.2026.09.021_bib43","doi-asserted-by":"crossref","first-page":"31864","DOI":"10.1021\/acsami.4c08603","article-title":"Polydopamine adhesion: Catechol, amine, dihydroxyindole, and aggregation dynamics","volume":"16","author":"Lim","year":"2024","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.bioactmat.2026.09.021_bib44","doi-asserted-by":"crossref","first-page":"6000","DOI":"10.1016\/j.ijleo.2016.04.019","article-title":"XRD Raman analysis and optical properties of CuS nanostructured film","volume":"127","author":"Hurma","year":"2016","journal-title":"Optik"},{"key":"10.1016\/j.bioactmat.2026.09.021_bib45","doi-asserted-by":"crossref","first-page":"3636","DOI":"10.1021\/jp064341w","article-title":"Microscale heat transfer transduced by Surface Plasmon resonant gold nanoparticles","volume":"111","author":"Roper","year":"2007","journal-title":"The journal of physical chemistry. C, Nanomaterials and interfaces"},{"key":"10.1016\/j.bioactmat.2026.09.021_bib46","doi-asserted-by":"crossref","first-page":"9494","DOI":"10.1039\/C4NR00708E","article-title":"Nanoparticles for photothermal therapies","volume":"6","author":"Jaque","year":"2014","journal-title":"Nanoscale"},{"key":"10.1016\/j.bioactmat.2026.09.021_bib47","doi-asserted-by":"crossref","DOI":"10.1016\/j.aca.2022.339995","article-title":"Polymer-assisted Au@PDA nanoparticles lyophilized powder with high stability and low adsorption and its application in colorimetric biosensing","volume":"1220","author":"Wang","year":"2022","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.bioactmat.2026.09.021_bib48","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1038\/s41392-025-02140-y","article-title":"Phototherapy in cancer treatment: strategies and challenges","volume":"10","author":"Cai","year":"2025","journal-title":"Signal Transduct. Targeted Ther."},{"key":"10.1016\/j.bioactmat.2026.09.021_bib49","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2024.149040","article-title":"Copper-based nanomaterials for biomedical applications","volume":"483","author":"Wei","year":"2024","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.bioactmat.2026.09.021_bib50","doi-asserted-by":"crossref","first-page":"4902","DOI":"10.1002\/anie.201712027","article-title":"Simultaneous fenton-like ion delivery and glutathione depletion by MnO(2) -Based nanoagent to enhance chemodynamic therapy","volume":"57","author":"Lin","year":"2018","journal-title":"Angew. Chem."},{"key":"10.1016\/j.bioactmat.2026.09.021_bib51","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.actbio.2022.05.030","article-title":"Copper-based theranostic nanocatalysts for synergetic photothermal-chemodynamic therapy","volume":"147","author":"Zuo","year":"2022","journal-title":"Acta Biomater."},{"key":"10.1016\/j.bioactmat.2026.09.021_bib52","article-title":"A PROTAC-Based cuproptosis sensitizer in lung cancer therapy","volume":"37","author":"Wang","year":"2025","journal-title":"Adv. Mater."},{"key":"10.1016\/j.bioactmat.2026.09.021_bib53","doi-asserted-by":"crossref","first-page":"13333","DOI":"10.1021\/acs.est.0c05287","article-title":"Electron spin resonance evidence for electro-generated Hydroxyl radicals","volume":"54","author":"Pei","year":"2020","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.bioactmat.2026.09.021_bib54","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1038\/s41422-022-00653-7","article-title":"Cuproptosis: a copper-triggered modality of mitochondrial cell death","volume":"32","author":"Tang","year":"2022","journal-title":"Cell Res."},{"key":"10.1016\/j.bioactmat.2026.09.021_bib55","article-title":"Copper and cuproptosis: mechanisms, biology, and roles in disease","author":"Wang","year":"2026","journal-title":"Science Bulletin"},{"key":"10.1016\/j.bioactmat.2026.09.021_bib56","first-page":"2136","article-title":"FAT1 inhibits cell migration and invasion by affecting cellular mechanical properties in esophageal squamous cell carcinoma","volume":"39","author":"Hu","year":"2018","journal-title":"Oncol. Rep."},{"key":"10.1016\/j.bioactmat.2026.09.021_bib57","doi-asserted-by":"crossref","first-page":"5178","DOI":"10.1038\/s41467-023-40851-4","article-title":"Biosynthesized gold nanoparticles that activate toll-like receptors and elicit localized light-converting hyperthermia for pleiotropic tumor immunoregulation","volume":"14","author":"Qin","year":"2023","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bioactmat.2026.09.021_bib58","doi-asserted-by":"crossref","first-page":"3167","DOI":"10.1002\/cam4.2148","article-title":"Therapeutic bacteria to combat cancer; current advances, challenges, and opportunities","volume":"8","author":"Sedighi","year":"2019","journal-title":"Cancer Med."},{"key":"10.1016\/j.bioactmat.2026.09.021_bib59","doi-asserted-by":"crossref","DOI":"10.1155\/2016\/8451728","article-title":"Bacteria in cancer therapy: Renaissance of an old concept","volume":"2016","author":"Felgner","year":"2016","journal-title":"International journal of microbiology"},{"key":"10.1016\/j.bioactmat.2026.09.021_bib60","doi-asserted-by":"crossref","DOI":"10.1016\/j.addr.2024.115216","article-title":"The interaction between particles and vascular endothelium in blood flow","volume":"207","author":"Li","year":"2024","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.bioactmat.2026.09.021_bib61","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1016\/j.jcis.2023.02.100","article-title":"Deciphering the adaption of bacterial cell wall mechanical integrity and turgor to different chemical or mechanical environments","volume":"640","author":"Han","year":"2023","journal-title":"J. Colloid Interface Sci."},{"key":"10.1016\/j.bioactmat.2026.09.021_bib62","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2025.123342","article-title":"Living therapeutics: precision diagnosis and therapy with engineered bacteria","volume":"321","author":"Xie","year":"2025","journal-title":"Biomaterials"},{"key":"10.1016\/j.bioactmat.2026.09.021_bib63","doi-asserted-by":"crossref","first-page":"2110","DOI":"10.1021\/acs.accounts.5c00271","article-title":"Regulating bacteria\u2013host interactions for disease intervention by covalent conjugation of bacterial surface","volume":"58","author":"Chen","year":"2025","journal-title":"Accounts Chem. Res."},{"key":"10.1016\/j.bioactmat.2026.09.021_bib64","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1021\/acs.accounts.3c00798","article-title":"Dopamine polymerization-mediated surface functionalization toward advanced bacterial therapeutics","volume":"57","author":"Wang","year":"2024","journal-title":"Accounts Chem. Res."},{"key":"10.1016\/j.bioactmat.2026.09.021_bib65","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1021\/acsbiomaterials.0c01589","article-title":"Hemocompatibility evaluation of biomaterials-the crucial impact of analyzed area","volume":"7","author":"Clauser","year":"2021","journal-title":"ACS Biomater. Sci. Eng."},{"key":"10.1016\/j.bioactmat.2026.09.021_bib66","doi-asserted-by":"crossref","first-page":"144","DOI":"10.5004\/dwt.2018.23128","article-title":"Experimental results for fluid phase equilibria of (n-propanol +water + salt) and comparison with predictions","volume":"132","author":"Yin","year":"2018","journal-title":"Desalination Water Treat."},{"key":"10.1016\/j.bioactmat.2026.09.021_bib67","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1038\/s41419-023-06110-6","article-title":"Stromal cells in the tumor microenvironment: accomplices of tumor progression?","volume":"14","author":"Zhao","year":"2023","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.bioactmat.2026.09.021_bib68","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1108\/MI-09-2017-0047","article-title":"High performance of quantum dots light-emitting diodes based on double transparent electrodes","volume":"35","author":"Li","year":"2018","journal-title":"Microelectron. Int."}],"container-title":["Bioactive Materials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2452199X26005542?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2452199X26005542?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T20:50:34Z","timestamp":1790283034000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2452199X26005542"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2027,2]]},"references-count":68,"alternative-id":["S2452199X26005542"],"URL":"https:\/\/doi.org\/10.1016\/j.bioactmat.2026.09.021","relation":{},"ISSN":["2452-199X"],"issn-type":[{"value":"2452-199X","type":"print"}],"subject":[],"published":{"date-parts":[[2027,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Engineered probiotics couple photothermal cuproptosis with biomechanical disruption and immune activation","name":"articletitle","label":"Article Title"},{"value":"Bioactive Materials","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bioactmat.2026.09.021","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Publishing services by Elsevier B.V. on behalf of KeAi Communications Co. Ltd.","name":"copyright","label":"Copyright"}]}}