{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T12:47:56Z","timestamp":1793882876813,"version":"4.7.0"},"reference-count":32,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100010040","name":"Taishan Scholar Project of Shandong Province","doi-asserted-by":"publisher","award":["tstp20240848"],"award-info":[{"award-number":["tstp20240848"]}],"id":[{"id":"10.13039\/501100010040","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005892","name":"China Academy of Chinese Medical Sciences","doi-asserted-by":"publisher","award":["CI2023E005TS02"],"award-info":[{"award-number":["CI2023E005TS02"]}],"id":[{"id":"10.13039\/501100005892","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005892","name":"China Academy of Chinese Medical Sciences","doi-asserted-by":"publisher","award":["CI2023E005TS05"],"award-info":[{"award-number":["CI2023E005TS05"]}],"id":[{"id":"10.13039\/501100005892","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005892","name":"China Academy of Chinese Medical Sciences","doi-asserted-by":"publisher","award":["CI2023E005TS09"],"award-info":[{"award-number":["CI2023E005TS09"]}],"id":[{"id":"10.13039\/501100005892","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005892","name":"China Academy of Chinese Medical Sciences","doi-asserted-by":"publisher","award":["CI2023E005TS08"],"award-info":[{"award-number":["CI2023E005TS08"]}],"id":[{"id":"10.13039\/501100005892","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005892","name":"China Academy of Chinese Medical Sciences","doi-asserted-by":"publisher","award":["CI2023E002"],"award-info":[{"award-number":["CI2023E002"]}],"id":[{"id":"10.13039\/501100005892","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005892","name":"China Academy of Chinese Medical Sciences","doi-asserted-by":"publisher","award":["ZG2024001-05"],"award-info":[{"award-number":["ZG2024001-05"]}],"id":[{"id":"10.13039\/501100005892","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005892","name":"China Academy of Chinese Medical Sciences","doi-asserted-by":"publisher","award":["CI2021A05101"],"award-info":[{"award-number":["CI2021A05101"]}],"id":[{"id":"10.13039\/501100005892","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005892","name":"China Academy of Chinese Medical Sciences","doi-asserted-by":"publisher","award":["ZYTS-2025012"],"award-info":[{"award-number":["ZYTS-2025012"]}],"id":[{"id":"10.13039\/501100005892","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005892","name":"China Academy of Chinese Medical Sciences","doi-asserted-by":"publisher","award":["ZYTS-2025006"],"award-info":[{"award-number":["ZYTS-2025006"]}],"id":[{"id":"10.13039\/501100005892","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005090","name":"Beijing Nova Program","doi-asserted-by":"publisher","award":["20240484502"],"award-info":[{"award-number":["20240484502"]}],"id":[{"id":"10.13039\/501100005090","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biomaterials Advances"],"published-print":{"date-parts":[[2026,5]]},"DOI":"10.1016\/j.bioadv.2025.214694","type":"journal-article","created":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T16:29:29Z","timestamp":1767025769000},"page":"214694","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Rosmarinic acid\/Se4+ self-assembled nanoparticles for combinational therapy of triple-negative breast cancer"],"prefix":"10.1016","volume":"182","author":[{"given":"Chong","family":"Qiu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyu","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingchao","family":"Tu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"LinYing","family":"Zhong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanfeng","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yinan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuqing","family":"Meng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiaoli","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junzhe","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuntao","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fei","family":"Xia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jigang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.bioadv.2025.214694_bb0005","doi-asserted-by":"crossref","DOI":"10.1002\/adma.202406662","article-title":"Engineering semiconducting polymeric nanoagonists potentiate cGAS-STING pathway activation and elicit long term memory against recurrence in breast cancer","volume":"37","author":"Yuan","year":"2025","journal-title":"Adv. Mater."},{"key":"10.1016\/j.bioadv.2025.214694_bb0010","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2023.122369","article-title":"Biomimetic Prussian blue nanocomplexes for chemo-photothermal treatment of triple-negative breast cancer by enhancing ICD","volume":"303","author":"Long","year":"2023","journal-title":"Biomaterials"},{"key":"10.1016\/j.bioadv.2025.214694_bb0015","article-title":"Bufotalin loaded biomimetic nanodrug for combined chemo\/photodynamic therapy of cancer","volume":"32","author":"Chen","year":"2025","journal-title":"Mater. Today Bio."},{"issue":"3","key":"10.1016\/j.bioadv.2025.214694_bb0020","article-title":"Cancer immunotherapy based on the bidirectional reprogramming of the tumor microenvironment by a \u201cbrakes off\/ step on the accelerator\u201d core-shell manganese phosphate\/siPD-L1 modulator","volume":"5","author":"Xia","year":"2025","journal-title":"Exploration (Beijing)."},{"key":"10.1016\/j.bioadv.2025.214694_bb0025","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2024.122608","article-title":"Shikonin and chitosan-silver nanoparticles synergize against triple-negative breast cancer through RIPK3-triggered necroptotic immunogenic cell death","volume":"309","author":"Liang","year":"2024","journal-title":"Biomaterials"},{"issue":"1","key":"10.1016\/j.bioadv.2025.214694_bb0030","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1186\/s12943-025-02242-9","article-title":"Multimodal lung cancer theranostics via manganese phosphate\/quercetin particle","volume":"24","author":"Qiu","year":"2025","journal-title":"Mol. Cancer"},{"issue":"2","key":"10.1016\/j.bioadv.2025.214694_bb0035","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1097\/st9.0000000000000070","article-title":"Drug innovation via integration of traditional Chinese and Western medicine","volume":"3","author":"Li","year":"2025","journal-title":"Sci. Tradit. Chin. Med."},{"issue":"11","key":"10.1016\/j.bioadv.2025.214694_bb0040","article-title":"The role of rosmarinic acid in cancer prevention and therapy: mechanisms of antioxidant and anticancer activity","volume":"13","author":"Kowalczyk","year":"2024","journal-title":"Antioxidants (Basel)."},{"key":"10.1016\/j.bioadv.2025.214694_bb0045","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2021.153861","article-title":"Rosmarinic acid decreases the malignancy of pancreatic cancer through inhibiting Gli1 signaling","volume":"95","author":"Zhou","year":"2022","journal-title":"Phytomedicine"},{"key":"10.1016\/j.bioadv.2025.214694_bb0050","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1016\/j.jconrel.2020.04.024","article-title":"Selenium and dopamine-crosslinked hyaluronic acid hydrogel for chemophotothermal cancer therapy","volume":"324","author":"Yang","year":"2020","journal-title":"J. Control. Release"},{"issue":"9","key":"10.1016\/j.bioadv.2025.214694_bb0055","doi-asserted-by":"crossref","DOI":"10.3390\/nu10091203","article-title":"Selenium, selenoproteins, and immunity","volume":"10","author":"Avery","year":"2018","journal-title":"Nutrients"},{"issue":"1","key":"10.1016\/j.bioadv.2025.214694_bb0060","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1186\/s12951-023-02165-x","article-title":"Advanced application of nanotechnology in active constituents of Traditional Chinese Medicines","volume":"21","author":"Qiu","year":"2023","journal-title":"J Nanobiotechnol."},{"key":"10.1016\/j.bioadv.2025.214694_bb0065","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2024.122851","article-title":"Gamabufotalin loaded micro-nanocomposites for multimodal therapy of metastatic TNBC by efficiently inducing ICD","volume":"314","author":"Fan","year":"2025","journal-title":"Biomaterials"},{"issue":"10","key":"10.1016\/j.bioadv.2025.214694_bb0070","doi-asserted-by":"crossref","DOI":"10.1002\/agt2.70149","article-title":"Natural polyphenol\u2013metal supramolecular nanocomplex for ferroptosis activation in chemoresistant hepatocellular carcinoma","volume":"6","author":"Qin","year":"2025","journal-title":"Aggregate"},{"issue":"15","key":"10.1016\/j.bioadv.2025.214694_bb0075","doi-asserted-by":"crossref","first-page":"10608","DOI":"10.1039\/D4RA01026D","article-title":"Cancer cell membrane-coated nanoparticles: a promising anti-tumor bionic platform","volume":"14","author":"Guo","year":"2024","journal-title":"RSC Adv."},{"issue":"6","key":"10.1016\/j.bioadv.2025.214694_bb0080","article-title":"Innovative utilization of cell membrane-coated nanoparticles in precision cancer therapy","volume":"4","author":"He","year":"2024","journal-title":"Exploration (Beijing)."},{"issue":"9","key":"10.1016\/j.bioadv.2025.214694_bb0085","doi-asserted-by":"crossref","first-page":"5895","DOI":"10.1021\/acs.nanolett.6b02786","article-title":"Preferential cancer cell self-recognition and tumor self-targeting by coating nanoparticles with homotypic cancer cell membranes","volume":"16","author":"Zhu","year":"2016","journal-title":"Nano Lett."},{"issue":"6","key":"10.1016\/j.bioadv.2025.214694_bb0090","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1515\/jtim-2024-0038","article-title":"Intratumoral microbiota in orchestrating cancer immunotherapy response","volume":"12","author":"Zou","year":"2024","journal-title":"J. Transl. Int. Med."},{"issue":"8","key":"10.1016\/j.bioadv.2025.214694_bb0095","article-title":"Recent advances of metal-polyphenol coordination polymers for biomedical applications","volume":"13","author":"Qin","year":"2023","journal-title":"Biosensors (Basel)."},{"issue":"36","key":"10.1016\/j.bioadv.2025.214694_bb0100","article-title":"Self-assembled Fe-phenolic acid network synergizes with ferroptosis to enhance tumor nanotherapy","volume":"20","author":"Chen","year":"2024","journal-title":"Small"},{"issue":"8","key":"10.1016\/j.bioadv.2025.214694_bb0105","doi-asserted-by":"crossref","DOI":"10.3390\/molecules29081686","article-title":"Herbal polyphenols as selenium reducers in the green synthesis of selenium nanoparticles: antibacterial and antioxidant capabilities of the obtained SeNPs","volume":"29","author":"Sentkowska","year":"2024","journal-title":"Molecules"},{"issue":"6","key":"10.1016\/j.bioadv.2025.214694_bb0110","doi-asserted-by":"crossref","first-page":"2052","DOI":"10.1021\/acssuschemeng.1c06048","article-title":"Green synthesis of robust selenium nanoparticles via polysaccharide\u2013polyphenol interaction: design principles and structure\u2013bioactivity relationship","volume":"10","author":"Zhou","year":"2022","journal-title":"ACS Sustain. Chem. Eng."},{"issue":"2","key":"10.1016\/j.bioadv.2025.214694_bb0115","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/s12011-010-8692-3","article-title":"Anti-hemolytic and peroxyl radical scavenging activity of organoselenium compounds: an in vitro study","volume":"140","author":"Kumar","year":"2011","journal-title":"Biol. Trace Elem. Res."},{"issue":"16","key":"10.1016\/j.bioadv.2025.214694_bb0120","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.202100598","article-title":"Selenium nanoparticles for biomedical applications: from development and characterization to therapeutics","volume":"10","author":"Ferro","year":"2021","journal-title":"Adv. Healthc. Mater."},{"issue":"21","key":"10.1016\/j.bioadv.2025.214694_bb0125","doi-asserted-by":"crossref","first-page":"5335","DOI":"10.3390\/cancers13215335","article-title":"Anticancer activity of biogenic selenium nanoparticles: apoptotic and immunogenic cell death markers in colon cancer cells","volume":"13","author":"Spyridopoulou","year":"2021","journal-title":"Cancers (Basel)"},{"issue":"6","key":"10.1016\/j.bioadv.2025.214694_bb0130","doi-asserted-by":"crossref","first-page":"2475","DOI":"10.1016\/j.apsb.2024.03.022","article-title":"Engineering nanomedicines for immunogenic eradication of cancer cells: recent trends and synergistic approaches","volume":"14","author":"Elzoghby","year":"2024","journal-title":"Acta Pharm. Sin. B"},{"issue":"7","key":"10.1016\/j.bioadv.2025.214694_bb0135","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1016\/j.ccell.2023.05.016","article-title":"Antiandrogen treatment induces stromal cell reprogramming to promote castration resistance in prostate cancer","volume":"41","author":"Wang","year":"2023","journal-title":"Cancer Cell"},{"issue":"4","key":"10.1016\/j.bioadv.2025.214694_bb0140","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1038\/s41590-022-01132-2","article-title":"Immunogenic cell stress and death","volume":"23","author":"Kroemer","year":"2022","journal-title":"Nat. Immunol."},{"issue":"22","key":"10.1016\/j.bioadv.2025.214694_bb0145","article-title":"Immunogenic cell death activates the tumor immune microenvironment to boost the immunotherapy efficiency","volume":"9","author":"Li","year":"2022","journal-title":"Adv. Sci. (Weinh)."},{"issue":"3","key":"10.1016\/j.bioadv.2025.214694_bb0150","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1039\/C9NR09039H","article-title":"Mitochondrion-targeted selenium nanoparticles enhance reactive oxygen species-mediated cell death","volume":"12","author":"Zhuang","year":"2020","journal-title":"Nanoscale"},{"issue":"23","key":"10.1016\/j.bioadv.2025.214694_bb0155","doi-asserted-by":"crossref","DOI":"10.1002\/smll.202300594","article-title":"Rosmarinic acid-crosslinked supramolecular nanoassembly with self-regulated photodynamic and anti-metastasis properties for synergistic photoimmunotherapy","volume":"19","author":"Zhou","year":"2023","journal-title":"Small"},{"issue":"6","key":"10.1016\/j.bioadv.2025.214694_bb0160","doi-asserted-by":"crossref","first-page":"6887","DOI":"10.1021\/acsnano.0c01018","article-title":"Nanoparticles derived from the natural antioxidant rosmarinic acid ameliorate acute inflammatory bowel disease","volume":"14","author":"Chung","year":"2020","journal-title":"ACS Nano"}],"container-title":["Biomaterials Advances"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2772950825005217?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2772950825005217?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T12:34:26Z","timestamp":1778934866000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2772950825005217"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":32,"alternative-id":["S2772950825005217"],"URL":"https:\/\/doi.org\/10.1016\/j.bioadv.2025.214694","relation":{},"ISSN":["2772-9508"],"issn-type":[{"value":"2772-9508","type":"print"}],"subject":[],"published":{"date-parts":[[2026,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Rosmarinic acid\/Se4+ self-assembled nanoparticles for combinational therapy of triple-negative breast cancer","name":"articletitle","label":"Article Title"},{"value":"Biomaterials Advances","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bioadv.2025.214694","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"214694"}}