{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T03:20:02Z","timestamp":1783048802742,"version":"3.54.6"},"reference-count":55,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82201778"],"award-info":[{"award-number":["82201778"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82571867"],"award-info":[{"award-number":["82571867"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002402","name":"Sun Yat-sen University","doi-asserted-by":"publisher","award":["24qnpy260"],"award-info":[{"award-number":["24qnpy260"]}],"id":[{"id":"10.13039\/501100002402","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biomaterials Advances"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.bioadv.2026.214950","type":"journal-article","created":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T15:23:28Z","timestamp":1779290608000},"page":"214950","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Metabolic reprogramming by microvesicle restores glycolysis and rescues nerve injury-induced erectile dysfunction via endogenous S1P-mediated MEK\/ERK signaling"],"prefix":"10.1016","volume":"187","author":[{"given":"Zhenkang","family":"Liang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zehong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuxuan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chaowei","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kangping","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weipeng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cui","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wende","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongbo","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bioadv.2026.214950_bb0005","doi-asserted-by":"crossref","DOI":"10.1136\/bmj.g129","article-title":"Erectile dysfunction","volume":"348","author":"Muneer","year":"2014","journal-title":"BMJ"},{"issue":"1","key":"10.1016\/j.bioadv.2026.214950_bb0010","doi-asserted-by":"crossref","first-page":"6667","DOI":"10.1038\/s41467-023-42367-3","article-title":"Preservation versus resection of denonvilliers\u2019 fascia in total mesorectal excision for male rectal cancer: follow-up analysis of the randomized PUF-01 trial","volume":"14","author":"Fang","year":"2023","journal-title":"Nat. Commun."},{"issue":"6","key":"10.1016\/j.bioadv.2026.214950_bb0015","doi-asserted-by":"crossref","first-page":"e473","DOI":"10.1097\/SLA.0000000000004591","article-title":"Effect of denonvilliers\u2019 fascia preservation versus resection during laparoscopic total mesorectal excision on postoperative urogenital function of male rectal cancer patients: initial results of Chinese PUF-01 randomized clinical trial","volume":"274","author":"Wei","year":"2021","journal-title":"Ann. Surg."},{"key":"10.1016\/j.bioadv.2026.214950_bb0020","doi-asserted-by":"crossref","DOI":"10.1016\/j.pharmthera.2020.107493","article-title":"Pharmacology and perspectives in erectile dysfunction in man","volume":"208","author":"Mitidieri","year":"2020","journal-title":"Pharmacol. Ther."},{"issue":"9861","key":"10.1016\/j.bioadv.2026.214950_bb0025","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/S0140-6736(12)60520-0","article-title":"Erectile dysfunction","volume":"381","author":"Shamloul","year":"2013","journal-title":"Lancet"},{"issue":"1","key":"10.1016\/j.bioadv.2026.214950_bb0030","article-title":"Hypoxia signaling in human health and diseases: implications and prospects for therapeutics","volume":"7","author":"Z","year":"2022","journal-title":"Signal Transduct. Target. Ther."},{"issue":"5","key":"10.1016\/j.bioadv.2026.214950_bb0035","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1038\/s41580-020-0227-y","article-title":"Cellular adaptation to hypoxia through hypoxia inducible factors and beyond","volume":"21","author":"Lee","year":"2020","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"3","key":"10.1016\/j.bioadv.2026.214950_bb0040","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/j.cmet.2020.02.002","article-title":"Restoring cellular energetics promotes axonal regeneration and functional recovery after spinal cord injury","volume":"31","author":"Han","year":"2020","journal-title":"Cell Metab."},{"issue":"2","key":"10.1016\/j.bioadv.2026.214950_bb0045","doi-asserted-by":"crossref","DOI":"10.1002\/SMMD.20230002","article-title":"Piezoelectric biomaterials for neural tissue engineering","volume":"2","author":"Xu","year":"2023","journal-title":"Smart Med."},{"issue":"16","key":"10.1016\/j.bioadv.2026.214950_bb0050","doi-asserted-by":"crossref","DOI":"10.3390\/ijms241612912","article-title":"Alterations of oligodendrocyte and myelin energy metabolism in multiple sclerosis","volume":"24","author":"L\u00f3pez-Muguruza","year":"2023","journal-title":"Int. J. Mol. Sci."},{"issue":"5","key":"10.1016\/j.bioadv.2026.214950_bb0055","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1016\/j.cmet.2020.08.015","article-title":"Glial metabolic rewiring promotes axon regeneration and functional recovery in the central nervous system","volume":"32","author":"Li","year":"2020","journal-title":"Cell Metab."},{"issue":"4","key":"10.1016\/j.bioadv.2026.214950_bb0060","article-title":"Shedding light on the cell biology of extracellular vesicles","volume":"19","author":"van N","year":"2018","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"7","key":"10.1016\/j.bioadv.2026.214950_bb0065","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1038\/s41580-023-00576-0","article-title":"Context-specific regulation of extracellular vesicle biogenesis and cargo selection","volume":"24","author":"Dixson","year":"2023","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"5","key":"10.1016\/j.bioadv.2026.214950_bb0070","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1038\/nrd3978","article-title":"Extracellular vesicles: biology and emerging therapeutic opportunities","volume":"12","author":"El Andaloussi","year":"2013","journal-title":"Nat. Rev. Drug Discov."},{"issue":"Pt A","key":"10.1016\/j.bioadv.2026.214950_bb0075","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.addr.2016.02.006","article-title":"Extracellular vesicles for drug delivery","volume":"106","author":"Vader","year":"2016","journal-title":"Adv. Drug Deliv. Rev."},{"issue":"4","key":"10.1016\/j.bioadv.2026.214950_bb0080","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.1172\/JCI81129","article-title":"Extracellular vesicle isolation and characterization: toward clinical application","volume":"126","author":"Xu","year":"2016","journal-title":"J. Clin. Invest."},{"issue":"22","key":"10.1016\/j.bioadv.2026.214950_bb0085","doi-asserted-by":"crossref","first-page":"13289","DOI":"10.1111\/jcmm.15946","article-title":"Exosomes derived from smooth muscle cells ameliorate diabetes-induced erectile dysfunction by inhibiting fibrosis and modulating the NO\/cGMP pathway","volume":"24","author":"Song","year":"2020","journal-title":"J. Cell. Mol. Med."},{"issue":"4","key":"10.1016\/j.bioadv.2026.214950_bb0090","doi-asserted-by":"crossref","first-page":"958","DOI":"10.3390\/cells9040958","article-title":"PC12 cell line: cell types, coating of culture vessels, differentiation and other culture conditions","volume":"9","author":"Wiatrak","year":"2020","journal-title":"Cells"},{"issue":"4","key":"10.1016\/j.bioadv.2026.214950_bb0095","doi-asserted-by":"crossref","DOI":"10.1093\/rb\/rbab031","article-title":"Metabolomics analysis of poly(l-lactic acid) nanofibers\u2019 performance on PC12 cell differentiation","volume":"8","author":"Su","year":"2021","journal-title":"Regen. Biomater."},{"issue":"4","key":"10.1016\/j.bioadv.2026.214950_bb0100","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1111\/jnc.15133","article-title":"The role of sphingolipids in myelination and myelin stability and their involvement in childhood and adult demyelinating disorders","volume":"156","author":"Giussani","year":"2021","journal-title":"J. Neurochem."},{"issue":"5","key":"10.1016\/j.bioadv.2026.214950_bb0105","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1007\/s00125-020-05085-9","article-title":"Diabetic neuropathy: what does the future hold?","volume":"63","author":"Callaghan","year":"2020","journal-title":"Diabetologia"},{"issue":"1","key":"10.1016\/j.bioadv.2026.214950_bb0110","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1186\/s12944-019-0965-z","article-title":"Role of cholesterol and sphingolipids in brain development and neurological diseases","volume":"18","author":"Hussain","year":"2019","journal-title":"Lipids Health Dis."},{"issue":"7","key":"10.1016\/j.bioadv.2026.214950_bb0115","article-title":"Glycosphingolipid metabolic reprogramming drives neural differentiation","volume":"37","author":"D","year":"2018","journal-title":"EMBO J."},{"key":"10.1016\/j.bioadv.2026.214950_bb0120","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms12086","article-title":"Sphingosine-1-phosphate promotes erythrocyte glycolysis and oxygen release for adaptation to high-altitude hypoxia","volume":"7","author":"Sun","year":"2016","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bioadv.2026.214950_bb0125","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2022.113511","article-title":"Stimulating the expression of sphingosine kinase 1 (SphK1) is beneficial to reduce acrylamide-induced nerve cell damage","volume":"237","author":"Yu","year":"2022","journal-title":"Ecotoxicol. Environ. Saf."},{"issue":"7","key":"10.1016\/j.bioadv.2026.214950_bb0130","article-title":"NGF-induced cell differentiation and gene activation is mediated by integrative nuclear FGFR1 signaling (INFS)","volume":"8","author":"L","year":"2013","journal-title":"PLoS One"},{"issue":"22","key":"10.1016\/j.bioadv.2026.214950_bb0135","doi-asserted-by":"crossref","first-page":"1875","DOI":"10.1016\/j.cub.2009.09.059","article-title":"ARF6-regulated shedding of tumor cell-derived plasma membrane microvesicles","volume":"19","author":"Muralidharan-Chari","year":"2009","journal-title":"Curr. Biol."},{"key":"10.1016\/j.bioadv.2026.214950_bb0140","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1016\/j.actbio.2023.07.015","article-title":"Functional recovery of injured cavernous nerves achieved through endogenous nerve growth factor-containing bioactive fibrous membrane","volume":"168","author":"Casanova","year":"2023","journal-title":"Acta Biomater."},{"key":"10.1016\/j.bioadv.2026.214950_bb0145","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2023.102938","article-title":"Dimethyl fumarate ameliorates erectile dysfunction in bilateral cavernous nerve injury rats by inhibiting oxidative stress and NLRP3 inflammasome-mediated pyroptosis of nerve via activation of Nrf2\/HO-1 signaling pathway","volume":"68","author":"Song","year":"2023","journal-title":"Redox Biol."},{"issue":"10","key":"10.1016\/j.bioadv.2026.214950_bb0150","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1038\/s41593-020-0689-4","article-title":"A glycolytic shift in schwann cells supports injured axons","volume":"23","author":"Babetto","year":"2020","journal-title":"Nat. Neurosci."},{"issue":"1","key":"10.1016\/j.bioadv.2026.214950_bb0155","doi-asserted-by":"crossref","DOI":"10.1186\/s12951-024-02536-y","article-title":"Enhancing intraneural revascularization following peripheral nerve injury through hypoxic Schwann-cell-derived exosomes: an insight into endothelial glycolysis","volume":"22","author":"Sun","year":"2024","journal-title":"J. Nanobiotechnol."},{"key":"10.1016\/j.bioadv.2026.214950_bb0160","article-title":"An inhibitory and beneficial effect of chlorpromazine and promethazine (C + P) on hyperglycolysis through HIF-1\u03b1 regulation in ischemic stroke","author":"G","year":"2021","journal-title":"Brain Res."},{"issue":"1","key":"10.1016\/j.bioadv.2026.214950_bb0165","doi-asserted-by":"crossref","first-page":"8182","DOI":"10.1038\/s41598-020-65182-y","article-title":"UGCG overexpression leads to increased glycolysis and increased oxidative phosphorylation of breast cancer cells","volume":"10","author":"Sch\u00f6mel","year":"2020","journal-title":"Sci. Rep."},{"issue":"3","key":"10.1016\/j.bioadv.2026.214950_bb0170","article-title":"Lactate homeostasis is maintained through regulation of glycolysis and lipolysis","volume":"37","author":"L","year":"2025","journal-title":"Cell Metab."},{"issue":"1","key":"10.1016\/j.bioadv.2026.214950_bb0175","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1186\/s12943-024-02119-3","article-title":"Altered metabolism in cancer: insights into energy pathways and therapeutic targets","volume":"23","author":"Tufail","year":"2024","journal-title":"Mol. Cancer"},{"issue":"6","key":"10.1016\/j.bioadv.2026.214950_bb0180","article-title":"Pancreatic acinar cells-derived sphingosine-1-phosphate contributes to fibrosis of chronic pancreatitis via inducing autophagy and activation of pancreatic stellate cells","volume":"165","author":"W","year":"2023","journal-title":"Gastroenterology"},{"issue":"11","key":"10.1016\/j.bioadv.2026.214950_bb0185","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1038\/s41423-022-00921-x","article-title":"S1P\/S1PR1 signaling differentially regulates the allogeneic response of CD4 and CD8 T cells by modulating mitochondrial fission","volume":"19","author":"Tian","year":"2022","journal-title":"Cell. Mol. Immunol."},{"issue":"7","key":"10.1016\/j.bioadv.2026.214950_bb0190","article-title":"Targeting the SphK1\/S1P\/S1PR1 axis that links obesity, chronic inflammation, and breast cancer metastasis","volume":"78","author":"N","year":"2018","journal-title":"Cancer Res."},{"issue":"2","key":"10.1016\/j.bioadv.2026.214950_bb0195","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/S1470-2045(13)70606-5","article-title":"Incidence of complications other than urinary incontinence or erectile dysfunction after radical prostatectomy or radiotherapy for prostate cancer: a population-based cohort study","volume":"15","author":"Nam","year":"2014","journal-title":"Lancet Oncol."},{"issue":"12","key":"10.1016\/j.bioadv.2026.214950_bb0200","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.202203087","article-title":"Melatonin-primed mesenchymal stem cells-derived small extracellular vesicles alleviated neurogenic erectile dysfunction by reversing phenotypic modulation","volume":"12","author":"Chen","year":"2023","journal-title":"Adv. Healthc. Mater."},{"key":"10.1016\/j.bioadv.2026.214950_bb0205","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.reth.2020.03.002","article-title":"Exosomes from adipose-derived stem cells protect against high glucose-induced erectile dysfunction by delivery of corin in a streptozotocin-induced diabetic rat model","volume":"14","author":"Wang","year":"2020","journal-title":"Regen. Ther."},{"issue":"2","key":"10.1016\/j.bioadv.2026.214950_bb0210","doi-asserted-by":"crossref","DOI":"10.1111\/and.12871","article-title":"Transplantation of adipose tissue-derived stem cell-derived exosomes ameliorates erectile function in diabetic rats","volume":"50","author":"Zhu","year":"2018","journal-title":"Andrologia"},{"key":"10.1016\/j.bioadv.2026.214950_bb0215","article-title":"Pyruvate dehydrogenase beta subunit (pdhb) promotes peripheral axon regeneration by regulating energy supply and gene expression","author":"J","year":"2023","journal-title":"Exp. Neurol."},{"issue":"26","key":"10.1016\/j.bioadv.2026.214950_bb0220","doi-asserted-by":"crossref","DOI":"10.1002\/smll.202310194","article-title":"Injectable hydrogel system incorporating black Phosphorus nanosheets and Tazarotene drug for enhanced vascular and nerve regeneration in spinal cord injury repair","volume":"20","author":"Liu","year":"2024","journal-title":"Small"},{"key":"10.1016\/j.bioadv.2026.214950_bb0225","article-title":"Multiple mechanisms of curcumin targeting spinal cord injury","volume":"159","author":"G","year":"2023","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.bioadv.2026.214950_bb0230","article-title":"Sequential oxygen supply system promotes peripheral nerve regeneration by enhancing Schwann cells survival and angiogenesis","volume":"289","author":"M","year":"2022","journal-title":"Biomaterials"},{"issue":"1","key":"10.1016\/j.bioadv.2026.214950_bb0235","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/s13045-024-01527-8","article-title":"Metabolic reprogramming in the tumor microenvironment of liver cancer","volume":"17","author":"Lin","year":"2024","journal-title":"J. Hematol. Oncol."},{"issue":"23","key":"10.1016\/j.bioadv.2026.214950_bb0240","doi-asserted-by":"crossref","first-page":"5068","DOI":"10.1016\/j.cell.2023.09.011","article-title":"Arginine reprograms metabolism in liver cancer via RBM39","volume":"186","author":"Mossmann","year":"2023","journal-title":"Cell"},{"issue":"1","key":"10.1016\/j.bioadv.2026.214950_bb0245","article-title":"The cancer metabolic reprogramming and immune response","volume":"20","author":"X","year":"2021","journal-title":"Mol. Cancer"},{"key":"10.1016\/j.bioadv.2026.214950_bb0250","doi-asserted-by":"crossref","DOI":"10.1016\/j.plipres.2023.101251","article-title":"Sphingosine 1-phosphate signaling during infection and immunity","volume":"92","author":"Mohammed","year":"2023","journal-title":"Prog. Lipid Res."},{"key":"10.1016\/j.bioadv.2026.214950_bb0255","article-title":"Significance of sphingosine-1-phosphate in cardiovascular physiology and pathology","volume":"156","author":"J","year":"2020","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.bioadv.2026.214950_bb0260","doi-asserted-by":"crossref","DOI":"10.1016\/j.pharmthera.2023.108381","article-title":"The role of sphingosine 1-phosphate metabolism in brain health and disease","volume":"244","author":"van Echten-Deckert","year":"2023","journal-title":"Pharmacol. Ther."},{"issue":"5","key":"10.1016\/j.bioadv.2026.214950_bb0265","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1016\/j.jaci.2023.05.028","article-title":"Sphingosine-1-phosphate induces airway smooth muscle hyperresponsiveness and proliferation","volume":"152","author":"Maguire","year":"2023","journal-title":"J. Allergy Clin. Immunol."},{"issue":"4","key":"10.1016\/j.bioadv.2026.214950_bb0270","article-title":"Siponimod exerts neuroprotective effects on the retina and higher visual pathway through neuronal S1PR1 in experimental glaucoma","volume":"18","author":"B","year":"2023","journal-title":"Neural Regen. Res."},{"issue":"8","key":"10.1016\/j.bioadv.2026.214950_bb0275","doi-asserted-by":"crossref","first-page":"5436","DOI":"10.1007\/s12035-018-1448-3","article-title":"The role of ceramide and sphingosine-1-phosphate in Alzheimer\u2019s disease and other neurodegenerative disorders","volume":"56","author":"Czubowicz","year":"2019","journal-title":"Mol. Neurobiol."}],"container-title":["Biomaterials Advances"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2772950826002487?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2772950826002487?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T03:08:20Z","timestamp":1783048100000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2772950826002487"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":55,"alternative-id":["S2772950826002487"],"URL":"https:\/\/doi.org\/10.1016\/j.bioadv.2026.214950","relation":{},"ISSN":["2772-9508"],"issn-type":[{"value":"2772-9508","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Metabolic reprogramming by microvesicle restores glycolysis and rescues nerve injury-induced erectile dysfunction via endogenous S1P-mediated MEK\/ERK signaling","name":"articletitle","label":"Article Title"},{"value":"Biomaterials Advances","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bioadv.2026.214950","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"214950"}}