{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:33:38Z","timestamp":1786120418590,"version":"build-2736575974"},"reference-count":42,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100019125","name":"National Institute of Pharmaceutical Education and Research, Ahmedabad","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100019125","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biomaterials Advances"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.bioadv.2026.215023","type":"journal-article","created":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T16:36:49Z","timestamp":1781627809000},"page":"215023","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Morphology-dependent toxicity and MRI contrasting properties of Mn3O4 nanostructures: A comparative study"],"prefix":"10.1016","volume":"188","author":[{"given":"Mahima","family":"Jadav","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vikas","family":"Yadav","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suraj","family":"Kendre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sachin B","family":"Jorvekar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roshan M.","family":"Borkar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayush","family":"Shukla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dinesh","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deep","family":"Pooja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7863-5581","authenticated-orcid":false,"given":"Awanish","family":"Mishra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hitesh","family":"Kulhari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bioadv.2026.215023_bb0005","series-title":"CLASSICS There\u2019s Plenty of Room at the Bottom An Invitation to Enter a New Field of Physics","author":"Feynman","year":"2011"},{"key":"10.1016\/j.bioadv.2026.215023_bb0010","series-title":"Theranostic Polymeric Nanoparticles as a New Approach in Cancer Therapy and Diagnosis: A Review","volume":"vol. 29","author":"Hosseini","year":"2023"},{"key":"10.1016\/j.bioadv.2026.215023_bb0015","series-title":"Nanotheranostics for Personalized Medicine","first-page":"257","volume":"vol. 13","author":"Kim","year":"2013"},{"key":"10.1016\/j.bioadv.2026.215023_bb0020","series-title":"Therapeutic Nanoparticles and Their Targeted Delivery Applications","volume":"vol. 25","author":"Yetisgin","year":"2020"},{"key":"10.1016\/j.bioadv.2026.215023_bb0025","series-title":"The Role of Nanoparticles and Nanomaterials in Cancer Diagnosis and Treatment: A Comprehensive Review","volume":"vol. 13","author":"Lan","year":"2023"},{"key":"10.1016\/j.bioadv.2026.215023_bb0030","series-title":"Organic and Inorganic Nanomaterials: Fabrication, Properties and Applications","first-page":"13735","volume":"vol. 13","author":"Alshammari","year":"2023"},{"key":"10.1016\/j.bioadv.2026.215023_bb0035","series-title":"Metal\/metal Oxide Nanoparticles: Toxicity Concerns Associated With Their Physical State and Remediation for Biomedical Applications","first-page":"1970","volume":"vol. 8","author":"Manuja","year":"2021"},{"key":"10.1016\/j.bioadv.2026.215023_bb0040","first-page":"142","article-title":"Magnetic nanoparticles as contrast agents in biomedical imaging: Recent advances in iron- and manganese-based magnetic nanoparticles","volume":"46","author":"Felton","year":"2014","journal-title":"Informa Healthc."},{"key":"10.1016\/j.bioadv.2026.215023_bb0045","doi-asserted-by":"crossref","first-page":"6852","DOI":"10.1021\/acsabm.0c00780","volume":"3","author":"Jain","year":"2020","journal-title":"ACS Appl. Bio Mater."},{"key":"10.1016\/j.bioadv.2026.215023_bb0050","doi-asserted-by":"crossref","first-page":"10170","DOI":"10.1021\/acsami.0c00331","volume":"12","author":"Jain","year":"2020","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.bioadv.2026.215023_bb0055","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1039\/C9TB02524C","volume":"8","author":"Jiang","year":"2020","journal-title":"J. Mater. Chem. B"},{"key":"10.1016\/j.bioadv.2026.215023_bb0060","doi-asserted-by":"crossref","DOI":"10.1002\/adbi.202300375","volume":"8","author":"Karthika","year":"2024","journal-title":"Adv. Biol."},{"key":"10.1016\/j.bioadv.2026.215023_bb0065","series-title":"Manganese-based MRI Contrast Agents: Past, Present, and Future","first-page":"8431","volume":"vol. 67","author":"Pan","year":"2011"},{"key":"10.1016\/j.bioadv.2026.215023_bb0070","doi-asserted-by":"crossref","first-page":"15548","DOI":"10.1021\/jacs.5b10748","volume":"137","author":"Gale","year":"2015","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.bioadv.2026.215023_bb0075","doi-asserted-by":"crossref","first-page":"1885","DOI":"10.1039\/c3tc00709j","volume":"1","author":"Giri","year":"2013","journal-title":"J. Mater. Chem. C Mater."},{"key":"10.1016\/j.bioadv.2026.215023_bb0080","volume":"20","author":"Li","year":"2022","journal-title":"J. Nanobiotechnol."},{"key":"10.1016\/j.bioadv.2026.215023_bb0085","series-title":"Research Advance in Manganese Nanoparticles in Cancer Diagnosis and Therapy","volume":"vol. 9","author":"Nie","year":"2022"},{"key":"10.1016\/j.bioadv.2026.215023_bb0090","doi-asserted-by":"crossref","first-page":"2323","DOI":"10.1039\/C1CS15188F","volume":"41","author":"Sharifi","year":"2012","journal-title":"Chem. Soc. Rev."},{"key":"10.1016\/j.bioadv.2026.215023_bb0095","series-title":"Synthesis, Functionalization, and Applications of Morphology-controllable silica-based Nanostructures: A Review","first-page":"1","volume":"vol. 44","author":"Sun","year":"2016"},{"key":"10.1016\/j.bioadv.2026.215023_bb0100","doi-asserted-by":"crossref","first-page":"4218","DOI":"10.1039\/C6CS00636A","article-title":"Cellular uptake of nanoparticles: journey inside the cell","volume":"46","author":"Behzadi","year":"2017","journal-title":"Roy. Soc. Chem."},{"key":"10.1016\/j.bioadv.2026.215023_bb0105","series-title":"Manganese Oxide Nanoplatforms for Disease Diagnosis and Treatment: Progress, Challenges and Opportunities","volume":"vol. 500","author":"Poon","year":"2024"},{"key":"10.1016\/j.bioadv.2026.215023_bb0110","doi-asserted-by":"crossref","DOI":"10.1186\/1477-3155-11-26","volume":"11","author":"Saptarshi","year":"2013","journal-title":"J. Nanobiotechnol."},{"key":"10.1016\/j.bioadv.2026.215023_bb0115","doi-asserted-by":"crossref","first-page":"1941","DOI":"10.1002\/smll.200700378","volume":"3","author":"Pan","year":"2007","journal-title":"Small"},{"key":"10.1016\/j.bioadv.2026.215023_bb0120","doi-asserted-by":"crossref","first-page":"8004","DOI":"10.1073\/pnas.1220143110","volume":"110","author":"Leifert","year":"2013","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bioadv.2026.215023_bb0125","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/j.colsurfb.2014.06.059","volume":"121","author":"Pooja","year":"2014","journal-title":"Colloids Surf. B: Biointerfaces"},{"key":"10.1016\/j.bioadv.2026.215023_bb0130","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1007\/s12035-014-8700-2","volume":"51","author":"Shailasree","year":"2015","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.bioadv.2026.215023_bb0135","series-title":"Nonspherical Metal-based Nanoarchitectures: Synthesis and Impact of Size, Shape, and Composition on Their Biological Activity","volume":"17","author":"Zare","year":"2021"},{"key":"10.1016\/j.bioadv.2026.215023_bb0140","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1093\/toxsci\/kfv114","volume":"147","author":"Mazzarino","year":"2015","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.bioadv.2026.215023_bb0145","series-title":"Toxic Potential of Materials at the Nanolevel","volume":"vol. 311","author":"Nel","year":"2006"},{"key":"10.1016\/j.bioadv.2026.215023_bb0150","doi-asserted-by":"crossref","DOI":"10.1155\/2017\/5478790","volume":"2017","author":"Alarifi","year":"2017","journal-title":"Biomed. Res. Int."},{"key":"10.1016\/j.bioadv.2026.215023_bb0155","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1002\/ppsc.201500251","volume":"33","author":"Neves","year":"2016","journal-title":"Part. Part. Syst. Charact."},{"key":"10.1016\/j.bioadv.2026.215023_bb0160","series-title":"Reactive Oxygen Species, Cellular Redox Systems, and Apoptosis","first-page":"749","volume":"vol. 48","author":"Circu","year":"2010"},{"issue":"3","key":"10.1016\/j.bioadv.2026.215023_bb0165","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/S0887-2333(02)00015-2","article-title":"Differential particulate air pollution induced oxidant stress in human granulocytes, monocytes and alveolar macrophages","volume":"16","author":"Becker","year":"2002","journal-title":"Toxicol. In Vitro"},{"key":"10.1016\/j.bioadv.2026.215023_bb0170","doi-asserted-by":"crossref","first-page":"3833","DOI":"10.1021\/cr2004508","article-title":"Recent advances in manganese oxide nanocrystals: fabrication, characterization, and microstructure","volume":"112","author":"Chen","year":"2012","journal-title":"Chem. Rev."},{"key":"10.1016\/j.bioadv.2026.215023_bb0175","doi-asserted-by":"crossref","first-page":"422","DOI":"10.3109\/17435390.2013.796017","volume":"8","author":"Misra","year":"2014","journal-title":"Nanotoxicology"},{"key":"10.1016\/j.bioadv.2026.215023_bb0180","doi-asserted-by":"crossref","DOI":"10.1016\/j.colsurfa.2023.131911","article-title":"Facile synthesis of metformin loaded Mn3O4-HAp magnetic hydroxyapatite nanocomposites for T1-magnetic resonance imaging guided targeted chemo-phototherapy in vitro","volume":"674","author":"Mushtaq","year":"2023","journal-title":"Coll. Surf. A Physicochem. Eng. Asp."},{"issue":"8","key":"10.1016\/j.bioadv.2026.215023_bb0185","doi-asserted-by":"crossref","DOI":"10.3390\/nano12081370","article-title":"Facile synthesis of multifunctional magnetoplasmonic Au-MnO hybrid nanocomposites for cancer theranostics","volume":"12","author":"Tian","year":"2022","journal-title":"Nanomaterials (Basel)"},{"key":"10.1016\/j.bioadv.2026.215023_bb0190","doi-asserted-by":"crossref","DOI":"10.1016\/j.materresbull.2021.111481","article-title":"Facile synthesis of Mn doped TiO2 rhombic nanocomposites for enhanced T1-magnetic resonance imaging and photodynamic therapy","volume":"144","author":"Mushtaq","year":"2021","journal-title":"Mater. Res. Bull."},{"key":"10.1016\/j.bioadv.2026.215023_bb0195","doi-asserted-by":"crossref","DOI":"10.1016\/j.colsurfb.2025.114789","article-title":"Metformin loaded Mn3O4@SiO2 core-shell nanoparticles for glioblastoma multiforme targeted therapy","volume":"254","author":"Nozhat","year":"2025","journal-title":"Colloids Surf. B: Biointerfaces"},{"key":"10.1016\/j.bioadv.2026.215023_bb0200","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2026.124219","article-title":"MOF nanosheets with topology enhanced ultrahigh relaxivity","volume":"333","author":"You","year":"2026","journal-title":"Biomaterials"},{"issue":"42","key":"10.1016\/j.bioadv.2026.215023_bb0205","doi-asserted-by":"crossref","first-page":"23131","DOI":"10.1021\/acs.analchem.5c02870","article-title":"The burst enhancement of MRI using magnetic resonance tuning based contrast agents","volume":"97","author":"You","year":"2025","journal-title":"Anal. Chem."},{"issue":"18","key":"10.1016\/j.bioadv.2026.215023_bb0210","doi-asserted-by":"crossref","first-page":"8628","DOI":"10.1021\/acs.nanolett.3c02466","article-title":"Hydrogen-bonded organic frameworks chelated manganese for precise magnetic resonance imaging diagnosis of cancers","volume":"23","author":"Ouyang","year":"2023","journal-title":"Nano Lett."}],"container-title":["Biomaterials Advances"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2772950826003213?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2772950826003213?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T21:34:06Z","timestamp":1786052046000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2772950826003213"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":42,"alternative-id":["S2772950826003213"],"URL":"https:\/\/doi.org\/10.1016\/j.bioadv.2026.215023","relation":{},"ISSN":["2772-9508"],"issn-type":[{"value":"2772-9508","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Morphology-dependent toxicity and MRI contrasting properties of Mn3O4 nanostructures: A comparative study","name":"articletitle","label":"Article Title"},{"value":"Biomaterials Advances","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bioadv.2026.215023","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"215023"}}