{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T19:51:50Z","timestamp":1791661910986,"version":"4.3.4"},"reference-count":52,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2009,7,1]],"date-time":"2009-07-01T00:00:00Z","timestamp":1246406400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2009,7,1]],"date-time":"2009-07-01T00:00:00Z","timestamp":1246406400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2009,7,1]],"date-time":"2009-07-01T00:00:00Z","timestamp":1246406400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2009,7,1]],"date-time":"2009-07-01T00:00:00Z","timestamp":1246406400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2009,7,1]],"date-time":"2009-07-01T00:00:00Z","timestamp":1246406400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2009,7,1]],"date-time":"2009-07-01T00:00:00Z","timestamp":1246406400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2009,7,1]],"date-time":"2009-07-01T00:00:00Z","timestamp":1246406400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100002920","name":"Research Grants Council, University Grants Committee","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002920","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The International Journal of Biochemistry & Cell Biology"],"published-print":{"date-parts":[[2009,7]]},"DOI":"10.1016\/j.biocel.2009.01.002","type":"journal-article","created":{"date-parts":[[2009,1,9]],"date-time":"2009-01-09T04:51:15Z","timestamp":1231476675000},"page":"1526-1535","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":103,"title":["Phycocyanin protects INS-1E pancreatic beta cells against human islet amyloid polypeptide-induced apoptosis through attenuating oxidative stress and modulating JNK and p38 mitogen-activated protein kinase pathways"],"prefix":"10.1016","volume":"41","author":[{"given":"Xiao-Ling","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gang","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianfeng","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yum-Shing","family":"Wong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hai-Lu","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rong-Rong","family":"Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xue-Mei","family":"Gu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter C.Y.","family":"Tong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliana C.N.","family":"Chan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.biocel.2009.01.002_bib1","doi-asserted-by":"crossref","first-page":"4522","DOI":"10.1210\/en.2004-0488","article-title":"Cross-talk between phosphatidylinositol 3-kinase\/AKT and c-jun NH2-terminal kinase mediates survival of isolated human islets","volume":"145","author":"Aikin","year":"2004","journal-title":"Endocrinology"},{"key":"10.1016\/j.biocel.2009.01.002_bib2","doi-asserted-by":"crossref","first-page":"974","DOI":"10.2337\/diabetes.52.4.974","article-title":"Differential activation mechanisms of Erk-1\/2 and p70 (S6K) by glucose in pancreatic beta-cells","volume":"52","author":"Briaud","year":"2003","journal-title":"Diabetes"},{"key":"10.1016\/j.biocel.2009.01.002_bib3","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.2337\/diabetes.53.6.1509","article-title":"Diabetes due to a progressive defect in beta-cell mass in rats transgenic for human islet amyloid polypeptide (HIP Rat): a new model for type 2 diabetes","volume":"53","author":"Butler","year":"2004","journal-title":"Diabetes"},{"key":"10.1016\/j.biocel.2009.01.002_bib4","doi-asserted-by":"crossref","first-page":"102","DOI":"10.2337\/diabetes.52.1.102","article-title":"Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes","volume":"52","author":"Butler","year":"2003","journal-title":"Diabetes"},{"key":"10.1016\/j.biocel.2009.01.002_bib5","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1051\/analusis:1999130","article-title":"Chemical composition and nutritional evaluation of some natural and commercial food products based on Spirulina","volume":"27","author":"Campanella","year":"1999","journal-title":"Analusis"},{"key":"10.1016\/j.biocel.2009.01.002_bib6","doi-asserted-by":"crossref","first-page":"2796","DOI":"10.1016\/j.fct.2008.05.012","article-title":"Subacute effects of methyl parathion on antioxidant defense systems and lipid peroxidation in rats","volume":"46","author":"Celik","year":"2008","journal-title":"Food Chem Toxicol"},{"key":"10.1016\/j.biocel.2009.01.002_bib7","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1038\/35065000","article-title":"Mammalian MAP kinase signalling cascades","volume":"410","author":"Chang","year":"2001","journal-title":"Nature"},{"key":"10.1016\/j.biocel.2009.01.002_bib8","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1006\/clim.2002.5257","article-title":"Glutamine protects activated human T cells from apoptosis by up-regulating glutathione and Bcl-2 levels","volume":"104","author":"Chang","year":"2002","journal-title":"Clin Immunol"},{"key":"10.1016\/j.biocel.2009.01.002_bib9","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1016\/j.ejphar.2008.02.020","article-title":"Protective effects of ACE inhibitors on vascular endothelial dysfunction induced by exogenous advanced oxidation protein products in rats","volume":"584","author":"Chen","year":"2008","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.biocel.2009.01.002_bib10","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1016\/j.biocel.2008.07.014","article-title":"Selenocystine induces caspase-independent apoptosis in MCF-7 human breast carcinoma cells with involvement of p53 phosphorylation and reactive oxygen species generation","volume":"41","author":"Chen","year":"2009","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"10.1016\/j.biocel.2009.01.002_bib11","doi-asserted-by":"crossref","first-page":"4352","DOI":"10.1021\/jf073399k","article-title":"In vitro antioxidant and antiproliferative activities of selenium-containing phycocyanin from selenium-enriched Spirulina platensis","volume":"56","author":"Chen","year":"2008","journal-title":"J Agric Food Chem"},{"key":"10.1016\/j.biocel.2009.01.002_bib12","doi-asserted-by":"crossref","first-page":"2424","DOI":"10.1016\/j.phytochem.2006.08.004","article-title":"Purification and characterization of selenium-containing phycocyanin from selenium-enriched Spirulina platensis","volume":"67","author":"Chen","year":"2006","journal-title":"Phytochemistry"},{"key":"10.1016\/j.biocel.2009.01.002_bib13","first-page":"151","article-title":"Islet amyloid, increased A-cells, reduced B-cells and exocrine fibrosis: quantitative changes in the pancreas in type 2 diabetes","volume":"9","author":"Clark","year":"1988","journal-title":"Diabetes Res"},{"key":"10.1016\/j.biocel.2009.01.002_bib14","doi-asserted-by":"crossref","first-page":"2296","DOI":"10.1016\/j.biocel.2008.03.015","article-title":"Neurotensin protects pancreatic beta cells from apoptosis","volume":"40","author":"Coppola","year":"2008","journal-title":"Int J Biochem Cell Biol"},{"key":"10.1016\/j.biocel.2009.01.002_bib15","first-page":"145","article-title":"Role of mitochondria in reactive oxygen species generation and removal; relevance to signaling and programmed cell death","volume":"52","author":"Czarna","year":"2006","journal-title":"Postepy Biochem"},{"key":"10.1016\/j.biocel.2009.01.002_bib16","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1210\/er.2001-0039","article-title":"Oxidative stress and stress-activated signaling pathways: a unifying hypothesis of type 2 diabetes","volume":"23","author":"Evans","year":"2002","journal-title":"Endocr Rev"},{"key":"10.1016\/j.biocel.2009.01.002_bib17","first-page":"287","article-title":"Type 2 diabetes mellitus as a conformational disease","volume":"6","author":"Hayden","year":"2005","journal-title":"JOP"},{"key":"10.1016\/j.biocel.2009.01.002_bib18","doi-asserted-by":"crossref","first-page":"697035","DOI":"10.1155\/2008\/697035","article-title":"Human islet amyloid polypeptide transgenic mice: in vivo and ex vivo models for the role of hIAPP in type 2 diabetes mellitus","volume":"2008","author":"Hoppener","year":"2008","journal-title":"Exp Diabetes Res"},{"key":"10.1016\/j.biocel.2009.01.002_bib19","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1016\/j.biocel.2005.12.009","article-title":"Role of islet amyloid in type 2 diabetes mellitus","volume":"38","author":"Hoppener","year":"2006","journal-title":"Int J Biochem Cell Biol"},{"key":"10.1016\/j.biocel.2009.01.002_bib20","doi-asserted-by":"crossref","first-page":"2016","DOI":"10.2337\/db07-0197","article-title":"High expression rates of human islet amyloid polypeptide induce endoplasmic reticulum stress mediated beta-cell apoptosis, a characteristic of humans with type 2 but not type 1 diabetes","volume":"56","author":"Huang","year":"2007","journal-title":"Diabetes"},{"key":"10.1016\/j.biocel.2009.01.002_bib21","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1006\/bbrc.1999.1989","article-title":"Fibrillar islet amyloid polypeptide differentially affects oxidative mechanisms and lipoprotein uptake in correlation with cytotoxicity in two insulin-producing cell lines","volume":"267","author":"Janciauskiene","year":"2000","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.biocel.2009.01.002_bib22","first-page":"974","article-title":"The mechanism of islet amyloid polypeptide toxicity is membrane disruption by intermediate-sized toxic amyloid particles","volume":"52","author":"Janson","year":"2003","journal-title":"Diabetes"},{"key":"10.1016\/j.biocel.2009.01.002_bib23","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/j.freeradbiomed.2006.10.047","article-title":"Reactive oxygen species in in vitro pesticide-induced neuronal cell (SH-SY5Y) cytotoxicity: role of NFkappaB and caspase-3","volume":"42","author":"Jia","year":"2007","journal-title":"Free Radic Biol Med"},{"key":"10.1016\/j.biocel.2009.01.002_bib24","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/s00125-002-1009-0","article-title":"The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of Type 2 diabetes","volume":"46","author":"Kahn","year":"2003","journal-title":"Diabetologia"},{"key":"10.1016\/j.biocel.2009.01.002_bib25","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1016\/j.biocel.2006.01.004","article-title":"Role of oxidative stress, endoplasmic reticulum stress, and c-Jun N-terminal kinase in pancreatic beta-cell dysfunction and insulin resistance","volume":"38","author":"Kaneto","year":"2006","journal-title":"Int J Biochem Cell Biol"},{"key":"10.1016\/j.biocel.2009.01.002_bib26","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.mce.2007.08.003","article-title":"Genistein protects pancreatic beta cells against cytokine-mediated toxicity","volume":"278","author":"Kim","year":"2007","journal-title":"Mol Cell Endocrinol"},{"key":"10.1016\/j.biocel.2009.01.002_bib27","doi-asserted-by":"crossref","first-page":"4949","DOI":"10.1111\/j.1742-4658.2005.04903.x","article-title":"Thiol reducing compounds prevent human amylin-evoked cytotoxicity","volume":"272","author":"Konarkowska","year":"2005","journal-title":"FEBS J"},{"key":"10.1016\/j.biocel.2009.01.002_bib28","doi-asserted-by":"crossref","first-page":"3614","DOI":"10.1111\/j.1742-4658.2006.05367.x","article-title":"The aggregation potential of human amylin determines its cytotoxicity towards islet beta-cells","volume":"273","author":"Konarkowska","year":"2006","journal-title":"FEBS J"},{"key":"10.1016\/j.biocel.2009.01.002_bib29","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/j.biocel.2006.09.007","article-title":"Apoptosis in the pathophysiology of diabetes mellitus","volume":"39","author":"Lee","year":"2007","journal-title":"Int J Biochem Cell Biol"},{"key":"10.1016\/j.biocel.2009.01.002_bib30","doi-asserted-by":"crossref","first-page":"1324","DOI":"10.2337\/db06-1579","article-title":"Toxic human islet amyloid polypeptide (h-IAPP) oligomers are intracellular, and vaccination to induce anti-toxic oligomer antibodies does not prevent h-IAPP-induced beta-cell apoptosis in h-IAPP transgenic mice","volume":"56","author":"Lin","year":"2007","journal-title":"Diabetes"},{"key":"10.1016\/j.biocel.2009.01.002_bib31","doi-asserted-by":"crossref","first-page":"E1317","DOI":"10.1152\/ajpendo.00082.2006","article-title":"Inhibition of human IAPP fibril formation does not prevent beta-cell death: evidence for distinct actions of oligomers and fibrils of human IAPP","volume":"291","author":"Meier","year":"2006","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"10.1016\/j.biocel.2009.01.002_bib32","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1016\/j.biocel.2007.11.019","article-title":"Protective effects of St. John's wort extract and its component hyperforin against cytokine-induced cytotoxicity in a pancreatic beta-cell line","volume":"40","author":"Menegazzi","year":"2008","journal-title":"Int J Biochem Cell Biol"},{"key":"10.1016\/j.biocel.2009.01.002_bib33","doi-asserted-by":"crossref","first-page":"1988","DOI":"10.1074\/jbc.271.4.1988","article-title":"Pore formation by the cytotoxic islet amyloid peptide amylin","volume":"271","author":"Mirzabekov","year":"1996","journal-title":"J Biol Chem"},{"key":"10.1016\/j.biocel.2009.01.002_bib34","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1038\/sj.cdd.4401830","article-title":"Reactive oxygen species mediate crosstalk between NF-kappaB and JNK","volume":"13","author":"Nakano","year":"2006","journal-title":"Cell Death Differ"},{"key":"10.1016\/j.biocel.2009.01.002_bib35","doi-asserted-by":"crossref","first-page":"16415","DOI":"10.1074\/jbc.273.26.16415","article-title":"Induction of apoptosis by SB202190 through inhibition of p38beta mitogen-activated protein kinase","volume":"273","author":"Nemoto","year":"1998","journal-title":"J Biol Chem"},{"key":"10.1016\/j.biocel.2009.01.002_bib36","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1089\/10966200152744463","article-title":"Role of Spirulina in the control of glycemia and lipidemia in type 2 diabetes mellitus","volume":"4","author":"Parikh","year":"2001","journal-title":"J Med Food"},{"key":"10.1016\/j.biocel.2009.01.002_bib37","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1038\/nchembio814","article-title":"Small-molecule activation of procaspase-3 to caspase-3 as a personalized anticancer strategy","volume":"2","author":"Putt","year":"2006","journal-title":"Nat Chem Biol"},{"key":"10.1016\/j.biocel.2009.01.002_bib38","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1038\/24055","article-title":"Cell suicide for beginners","volume":"396","author":"Raff","year":"1998","journal-title":"Nature"},{"key":"10.1016\/j.biocel.2009.01.002_bib39","doi-asserted-by":"crossref","first-page":"3100","DOI":"10.1038\/sj.onc.1210392","article-title":"Differential regulation and properties of MAPKs","volume":"26","author":"Raman","year":"2007","journal-title":"Oncogene"},{"key":"10.1016\/j.biocel.2009.01.002_bib40","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1016\/S0024-3205(01)01185-7","article-title":"Spirulina maxima prevents fatty liver formation in CD-1 male and female mice with experimental diabetes","volume":"69","author":"Rodriguez-Hernandez","year":"2001","journal-title":"Life Sci"},{"key":"10.1016\/j.biocel.2009.01.002_bib41","doi-asserted-by":"crossref","first-page":"207","DOI":"10.2174\/1389203033487216","article-title":"C-phycocyanin: a biliprotein with antioxidant, anti-inflammatory and neuroprotective effects","volume":"4","author":"Romay","year":"2003","journal-title":"Curr Protein Pept Sci"},{"key":"10.1016\/j.biocel.2009.01.002_bib42","doi-asserted-by":"crossref","first-page":"1751","DOI":"10.1515\/BC.2002.196","article-title":"Amylin-induced cytotoxicity is associated with activation of caspase-3 and MAP kinases","volume":"383","author":"Rumora","year":"2002","journal-title":"Biol Chem"},{"key":"10.1016\/j.biocel.2009.01.002_bib43","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1007\/s125-002-8248-z","article-title":"Reduced beta-cell mass and expression of oxidative stress-related DNA damage in the islet of Japanese Type II diabetic patients","volume":"45","author":"Sakuraba","year":"2002","journal-title":"Diabetologia"},{"key":"10.1016\/j.biocel.2009.01.002_bib44","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1038\/nrm1963","article-title":"Poly(ADP-ribose): novel functions for an old molecule","volume":"7","author":"Schreiber","year":"2006","journal-title":"Nat Rev Mol Cell Biol"},{"key":"10.1016\/j.biocel.2009.01.002_bib45","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1016\/j.freeradbiomed.2005.10.056","article-title":"JNK signaling pathway is a key modulator in cell death mediated by reactive oxygen and nitrogen species","volume":"40","author":"Shen","year":"2006","journal-title":"Free Radic Biol Med"},{"key":"10.1016\/j.biocel.2009.01.002_bib46","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.freeradbiomed.2006.01.021","article-title":"The various aggregation states of beta-amyloid 1-42 mediate different effects on oxidative stress, neurodegeneration, and BACE-1 expression","volume":"41","author":"Tamagno","year":"2006","journal-title":"Free Radic Biol Med"},{"key":"10.1016\/j.biocel.2009.01.002_bib47","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1006\/bbrc.1998.9149","article-title":"Hepatoprotective effect of C-phycocyanin: protection for carbon tetrachloride and R-(+)-pulegone-mediated hepatotoxicty in rats","volume":"249","author":"Vadiraja","year":"1998","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.biocel.2009.01.002_bib48","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.biocel.2006.07.001","article-title":"Free radicals and antioxidants in normal physiological functions and human disease","volume":"39","author":"Valko","year":"2007","journal-title":"Int J Biochem Cell Biol"},{"key":"10.1016\/j.biocel.2009.01.002_bib49","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1002\/jnr.20570","article-title":"Olanzapine and quetiapine protect PC12 cells from beta-amyloid peptide(25-35)-induced oxidative stress and the ensuing apoptosis","volume":"81","author":"Wang","year":"2005","journal-title":"J Neurosci Res"},{"key":"10.1016\/j.biocel.2009.01.002_bib50","doi-asserted-by":"crossref","first-page":"3779","DOI":"10.1111\/j.1742-4658.2006.05386.x","article-title":"Activation of activating transcription factor 2 by p38 MAP kinase during apoptosis induced by human amylin in cultured pancreatic beta-cells","volume":"273","author":"Zhang","year":"2006","journal-title":"FEBS J"},{"key":"10.1016\/j.biocel.2009.01.002_bib51","doi-asserted-by":"crossref","first-page":"52810","DOI":"10.1074\/jbc.M308244200","article-title":"Fibrillogenic amylin evokes islet beta-cell apoptosis through linked activation of a caspase cascade and JNK1","volume":"278","author":"Zhang","year":"2003","journal-title":"J Biol Chem"},{"key":"10.1016\/j.biocel.2009.01.002_bib52","doi-asserted-by":"crossref","first-page":"2759","DOI":"10.2337\/diabetes.52.11.2759","article-title":"Prevalence and clinicopathological characteristics of islet amyloid in Chinese patients with type 2 diabetes","volume":"52","author":"Zhao","year":"2003","journal-title":"Diabetes"}],"updated-by":[{"DOI":"10.1016\/j.biocel.2026.107015","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2026,8,30]],"date-time":"2026-08-30T00:00:00Z","timestamp":1788048000000}},{"DOI":"10.1016\/j.biocel.2026.107015","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000}}],"container-title":["The International Journal of Biochemistry & Cell Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1357272509000053?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1357272509000053?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T19:36:49Z","timestamp":1791661009000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1357272509000053"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,7]]},"references-count":52,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2009,7]]}},"alternative-id":["S1357272509000053"],"URL":"https:\/\/doi.org\/10.1016\/j.biocel.2009.01.002","relation":{},"ISSN":["1357-2725"],"issn-type":[{"value":"1357-2725","type":"print"}],"subject":[],"published":{"date-parts":[[2009,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Phycocyanin protects INS-1E pancreatic beta cells against human islet amyloid polypeptide-induced apoptosis through attenuating oxidative stress and modulating JNK and p38 mitogen-activated protein kinase pathways","name":"articletitle","label":"Article Title"},{"value":"The International Journal of Biochemistry & Cell Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biocel.2009.01.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2009 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}