{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T06:59:07Z","timestamp":1761202747784,"version":"build-2065373602"},"reference-count":72,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2014,10,1]],"date-time":"2014-10-01T00:00:00Z","timestamp":1412121600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,10,1]],"date-time":"2014-10-01T00:00:00Z","timestamp":1412121600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The International Journal of Biochemistry &amp; Cell Biology"],"published-print":{"date-parts":[[2014,10]]},"DOI":"10.1016\/j.biocel.2014.09.003","type":"journal-article","created":{"date-parts":[[2014,9,8]],"date-time":"2014-09-08T12:40:09Z","timestamp":1410180009000},"page":"252-263","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"special_numbering":"C","title":["Elevated dopamine induces minimal hepatic encephalopathy by activation of astrocytic NADPH oxidase and astrocytic protein tyrosine nitration"],"prefix":"10.1016","volume":"55","author":[{"given":"Saidan","family":"Ding","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianjing","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leping","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yiru","family":"Ye","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuebao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiangnan","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bicheng","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qichuan","family":"Zhuge","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.biocel.2014.09.003_bib0005","article-title":"Executive functions in chronic hepatitis C virus-infected elderly patients","author":"Abdel Rahman","year":"2014","journal-title":"Geriatr Gerontol Int"},{"key":"10.1016\/j.biocel.2014.09.003_bib0010","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1016\/0016-5085(90)90298-F","article-title":"Increased brain uptake of gamma-aminobutyric acid in a rabbit model of hepatic encephalopathy","volume":"98","author":"Bassett","year":"1990","journal-title":"Gastroenterology"},{"issue":"9","key":"10.1016\/j.biocel.2014.09.003_bib0015","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1172\/JCI18212","article-title":"NADPH oxidase signal transduces angiotensin II in hepatic stellate cells and is critical in hepatic fibrosis","volume":"112","author":"Bataller","year":"2003","journal-title":"J Clin Invest"},{"key":"10.1016\/j.biocel.2014.09.003_bib0020","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1002\/(SICI)1097-4547(19980501)52:3<307::AID-JNR7>3.0.CO;2-H","article-title":"Ionic mechanisms in glutamate-induced astrocyte swelling: role of K+ influx","volume":"52","author":"Bender","year":"1998","journal-title":"J Neurosci Res"},{"key":"10.1016\/j.biocel.2014.09.003_bib0025","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1007\/BF00964814","article-title":"Monoamines and metabolites in autopsied brain tissue from cirrhotic patients with hepatic encephalopathy","volume":"14","author":"Bergeron","year":"1989","journal-title":"Neurochemical Res"},{"key":"10.1016\/j.biocel.2014.09.003_bib0030","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1097\/00001756-199601310-00050","article-title":"Hippocampal cGMP and cAMP are differentially involved in memory processing of inhibitory avoidance learning","volume":"7","author":"Bernabeu","year":"1996","journal-title":"NeuroReport"},{"key":"10.1016\/j.biocel.2014.09.003_bib0035","doi-asserted-by":"crossref","first-page":"1324","DOI":"10.1523\/JNEUROSCI.16-04-01324.1996","article-title":"Superoxide production in rat hippocampal neurons: selective imaging with hydroethidine","volume":"16","author":"Bindokas","year":"1996","journal-title":"J Neurosci"},{"key":"10.1016\/j.biocel.2014.09.003_bib0040","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1016\/S0168-8278(99)80361-4","article-title":"Pathophysiology of cerebral edema in fulminant hepatic failure","volume":"31","author":"Blei","year":"1999","journal-title":"J Hepatol"},{"key":"10.1016\/j.biocel.2014.09.003_bib0045","doi-asserted-by":"crossref","first-page":"2692","DOI":"10.1182\/blood-2002-04-1149","article-title":"Current molecular models for NADPH oxidase regulation by Rac GTPase","volume":"100","author":"Bokoch","year":"2002","journal-title":"Blood"},{"key":"10.1016\/j.biocel.2014.09.003_bib0050","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1023\/A:1027347019707","article-title":"Release of [3H]dopamine from striatal and cerebral cortical slices from rats with thioacetamide-induced hepatic encephalopathy: different responses to stimulation by potassium ions and agonists of ionotropic glutamate receptors","volume":"22","author":"Borkowska","year":"1997","journal-title":"Neurochem Res"},{"key":"10.1016\/j.biocel.2014.09.003_bib0055","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/S0304-3940(99)00412-7","article-title":"N-methyl-d-aspartate-evoked changes in the striatal extracellular levels of dopamine and its metabolites in vivo in rats with acute hepatic encephalopathy","volume":"268","author":"Borkowska","year":"1999","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.biocel.2014.09.003_bib0060","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1002\/(SICI)1097-4547(19991115)58:4<576::AID-JNR10>3.0.CO;2-D","article-title":"Oxidative stress-induced metabolic alterations in rat brain astrocytes studied by multinuclear NMR spectroscopy","volume":"58","author":"Brand","year":"1999","journal-title":"J Neurosci Res"},{"key":"10.1016\/j.biocel.2014.09.003_bib0065","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1038\/nrgastro.2013.99","article-title":"The liver-brain axis in liver failure: neuroinflammation and encephalopathy","volume":"10","author":"Butterworth","year":"2013","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"10.1016\/j.biocel.2014.09.003_bib0070","article-title":"Lipopolysaccharide precipitates hepatic encephalopathy and increases blood-brain barrier permeability in mice with acute liver failure","author":"Chastre","year":"2013","journal-title":"Liver Int"},{"key":"10.1016\/j.biocel.2014.09.003_bib0075","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1111\/j.2042-7158.1993.tb05537.x","article-title":"Effect of Bay K 8644 on the synthesis and metabolism of dopamine and 5-hydroxytryptamine in various brain areas of the rat","volume":"45","author":"Colado","year":"1993","journal-title":"J Pharm Pharmacol"},{"key":"10.1016\/j.biocel.2014.09.003_bib0090","doi-asserted-by":"crossref","first-page":"3721","DOI":"10.1093\/brain\/aws273","article-title":"Distinct roles of dopamine and subthalamic nucleus in learning and probabilistic decision making","volume":"135","author":"Coulthard","year":"2012","journal-title":"Brain"},{"key":"10.1016\/j.biocel.2014.09.003_bib0095","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1007\/s12664-009-0003-6","article-title":"Minimal hepatic encephalopathy","volume":"28","author":"Dhiman","year":"2009","journal-title":"Indian J Gastroenterol"},{"key":"10.1016\/j.biocel.2014.09.003_bib0100","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1007\/s12072-013-9431-6","article-title":"Dopamine from cirrhotic liver contributes to the impaired learning and memory ability of hippocampus in minimal hepatic encephalopathy","volume":"7","author":"Ding","year":"2013","journal-title":"Hepatol Int"},{"key":"10.1016\/j.biocel.2014.09.003_bib0105","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/S0736-5748(99)00084-2","article-title":"Association between cell swelling and glycogen content in cultured astrocytes","volume":"18","author":"Dombro","year":"2000","journal-title":"Int J Dev Neurosci"},{"key":"10.1016\/j.biocel.2014.09.003_bib0110","first-page":"262","article-title":"The uptake of 36C1 into astrocytes in tissue culture by a potassium-dependent, saturable process: implications for epilepsy and cortical edema","volume":"98","author":"Gill","year":"1973","journal-title":"Trans Am Neurol Assoc"},{"key":"10.1016\/j.biocel.2014.09.003_bib0115","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1111\/j.1478-3231.2010.02289.x","article-title":"Cerebral oedema in minimal hepatic encephalopathy due to extrahepatic portal venous obstruction","volume":"30","author":"Goel","year":"2010","journal-title":"Liver Int"},{"key":"10.1016\/j.biocel.2014.09.003_bib0120","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1053\/jhep.2003.50061","article-title":"Benzodiazepine-induced protein tyrosine nitration in rat astrocytes","volume":"37","author":"G\u00f6rg","year":"2003","journal-title":"Hepatology"},{"key":"10.1016\/j.biocel.2014.09.003_bib0125","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.abb.2006.02.012","article-title":"Inflammatory cytokines induce protein tyrosine nitration in rat astrocytes","volume":"449","author":"G\u00f6rg","year":"2006","journal-title":"Arch Biochem Biophys"},{"key":"10.1016\/j.biocel.2014.09.003_bib0135","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.abb.2013.03.010","article-title":"Osmotic and oxidative\/nitrosative stress in ammonia toxicity and hepatic encephalopathy","volume":"536","author":"G\u00f6rg","year":"2013","journal-title":"Arch Biochem Biophys"},{"key":"10.1016\/j.biocel.2014.09.003_bib0140","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/S0092-8674(03)00314-3","article-title":"Molecular basis of phosphorylation-induced activation of the NADPH oxidase","volume":"113","author":"Groemping","year":"2003","journal-title":"Cell"},{"key":"10.1016\/j.biocel.2014.09.003_bib0145","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1002\/hep.21235","article-title":"Low grade cerebral edema and the pathogenesis of hepatic encephalopathy in cirrhosis","volume":"43","author":"H\u00e4ussinger","year":"2006","journal-title":"Hepatology"},{"key":"10.1016\/j.biocel.2014.09.003_bib0160","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1097\/01.shk.0000131193.80038.f1","article-title":"Changes in CSF S100B and cytokine concentrations in early-phase severe traumatic brain injury","volume":"22","author":"Hayakata","year":"2004","journal-title":"Shock"},{"key":"10.1016\/j.biocel.2014.09.003_bib0165","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0014-2999(89)90458-5","article-title":"Differential effects of pimozide and SCH 23390 on acquisition of learning in mice","volume":"164","author":"Ichihara","year":"1989","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.biocel.2014.09.003_bib0170","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1007\/BF02253713","article-title":"Utility of an elevated plus-maze for the evaluation of memory in mice: effects of nootropics, scopolamine and electroconvulsive shock","volume":"101","author":"Itoh","year":"1990","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.biocel.2014.09.003_bib0180","doi-asserted-by":"crossref","first-page":"908","DOI":"10.3748\/wjg.v11.i6.908","article-title":"Comparison of probiotics and lactulose in the treatment of minimal hepatic encephalopathy in rats","volume":"11","author":"Jia","year":"2005","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.biocel.2014.09.003_bib0185","doi-asserted-by":"crossref","first-page":"35147","DOI":"10.1074\/jbc.273.52.35147","article-title":"Activation of p47(PHOX), a cytosolic subunit of the leukocyte NADPH oxidase. Phosphorylation of ser-359 or ser-370 precedes phosphorylation at other sites and is required for activity","volume":"273","author":"Johnson","year":"1998","journal-title":"J Biol Chem"},{"key":"10.1016\/j.biocel.2014.09.003_bib0190","doi-asserted-by":"crossref","first-page":"2826","DOI":"10.1111\/j.0953-816X.2004.03397.x","article-title":"Targeted introduction of V642I mutation in amyloid precursor protein gene causes functional abnormality resembling early stage of Alzheimer's disease in aged mice","volume":"19","author":"Kawasumi","year":"2004","journal-title":"Eur J Neurosci"},{"key":"10.1016\/j.biocel.2014.09.003_bib0195","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1111\/j.1471-4159.1992.tb09315.x","article-title":"Glutamate receptor agonists stimulate nitric oxide synthase in primary cultures of cerebellar granule cells","volume":"58","author":"Kiedrowski","year":"1992","journal-title":"J Neurochem"},{"key":"10.1016\/j.biocel.2014.09.003_bib0200","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1016\/0003-2697(75)90649-1","article-title":"A method using 3-O-methyl-d-glucose and phloretin for the determination of intracellular water space of cells in monolayer culture","volume":"68","author":"Kletzien","year":"1975","journal-title":"Anal Biochem"},{"key":"10.1016\/j.biocel.2014.09.003_bib0205","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1136\/bmj.1.5907.549","article-title":"Dopamine and serotonin metabolism in hepatic encephalopathy","volume":"1","author":"Knell","year":"1974","journal-title":"Br Med J"},{"key":"10.1016\/j.biocel.2014.09.003_bib0215","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1007\/s00702-005-0389-y","article-title":"Glutathione peroxidase-1 contributes to the protection of glutamine synthetase in astrocytes during oxidative stress","volume":"113","author":"Knorpp","year":"2006","journal-title":"J Neural Transm"},{"key":"10.1016\/j.biocel.2014.09.003_bib0220","doi-asserted-by":"crossref","first-page":"e50250","DOI":"10.1371\/journal.pone.0050250","article-title":"Dissociation between active and observational learning from positive and negative feedback in Parkinsonism","volume":"7","author":"Kobza","year":"2012","journal-title":"PLoS ONE"},{"key":"10.1016\/j.biocel.2014.09.003_bib0225","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1002\/glia.20737","article-title":"Hypoosmotic swelling affects zinc homeostasis in cultured rat astrocytes","volume":"57","author":"Kruczek","year":"2009","journal-title":"Glia"},{"key":"10.1016\/j.biocel.2014.09.003_bib0230","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.abb.2013.05.004","article-title":"Precipitants of hepatic encephalopathy induce rapid astrocyte swelling in an oxidative stress dependent manner","volume":"536","author":"Lachmann","year":"2013","journal-title":"Arch Biochem Biophys"},{"key":"10.1016\/j.biocel.2014.09.003_bib0235","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1111\/j.1471-4159.2010.06630.x","article-title":"Curcumin attenuates cerebral edema following traumatic brain injury in mice: a possible role for aquaporin-4?","volume":"113","author":"Laird","year":"2010","journal-title":"J Neurochem"},{"key":"10.1016\/j.biocel.2014.09.003_bib0240","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1038\/jcbfm.1991.67","article-title":"Cerebral ammonia metabolism in patients with severe liver disease and minimal hepatic encephalopathy","volume":"11","author":"Lockwood","year":"1991","journal-title":"J Cereb Blood Flow Metab"},{"key":"10.1016\/j.biocel.2014.09.003_bib0245","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/S0006-8993(97)01406-6","article-title":"Enhancement of spatial attention in nociceptin\/orphanin FQ receptor-knockout mice","volume":"783","author":"Mamiya","year":"1998","journal-title":"Brain Res"},{"key":"10.1016\/j.biocel.2014.09.003_bib0250","doi-asserted-by":"crossref","first-page":"1356","DOI":"10.1126\/science.14400","article-title":"Glutamine synthetase: glial localization in brain","volume":"195","author":"Martinez-Hernandez","year":"1977","journal-title":"Science"},{"key":"10.1016\/j.biocel.2014.09.003_bib0255","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1016\/j.mehy.2013.08.005","article-title":"A new hypothesis on the manifestation of cerebral malaria: the secret is in the liver","volume":"81","author":"Martins","year":"2013","journal-title":"Med Hypotheses"},{"key":"10.1016\/j.biocel.2014.09.003_bib0265","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1007\/s11894-010-0150-z","article-title":"Advances in the evaluation and management of minimal hepatic encephalopathy","volume":"13","author":"Montgomery","year":"2011","journal-title":"Curr Gastroenterol Rep"},{"key":"10.1016\/j.biocel.2014.09.003_bib0275","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1159\/000341999","article-title":"Dissociating the cognitive effects of levodopa versus dopamine agonists in a neurocomputational model of learning in Parkinson's disease","volume":"11","author":"Moustafa","year":"2013","journal-title":"Neuro-Degen Dis"},{"key":"10.1016\/j.biocel.2014.09.003_bib0280","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1038\/sj.bjp.0703401","article-title":"Apocynin inhibits peroxynitrite formation by murine macrophages","volume":"130","author":"Muijsers","year":"2000","journal-title":"Br J Pharmacol"},{"key":"10.1016\/j.biocel.2014.09.003_bib0285","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1007\/s00418-004-0679-8","article-title":"Assembly of the phagocyte NADPH oxidase","volume":"122","author":"Nauseef","year":"2004","journal-title":"Histochem Cell Biol"},{"key":"10.1016\/j.biocel.2014.09.003_bib0290","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1097\/00005072-199405000-00001","article-title":"Astrocyte responses to CNS injury","volume":"53","author":"Norenberg","year":"1994","journal-title":"J Neuropathol Exp Neurol"},{"key":"10.1016\/j.biocel.2014.09.003_bib0295","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1055\/s-2007-1007237","article-title":"Astrocytic\u2013ammonia interactions in hepatic encephalopathy","volume":"16","author":"Norenberg","year":"1996","journal-title":"Semin Liver Dis"},{"key":"10.1016\/j.biocel.2014.09.003_bib0300","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1007\/BF00965694","article-title":"Ammonia-induced astrocyte swelling in primary culture","volume":"16","author":"Norenberg","year":"1991","journal-title":"Neurochem Res"},{"key":"10.1016\/j.biocel.2014.09.003_bib0305","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1007\/s11011-005-7911-7","article-title":"Mechanisms of ammonia-induced astrocyte swelling","volume":"20","author":"Norenberg","year":"2005","journal-title":"Metab Brain Dis"},{"key":"10.1016\/j.biocel.2014.09.003_bib0310","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1080\/15216540252774702","article-title":"Cell compartmentalization in redox signaling","volume":"52","author":"Pani","year":"2001","journal-title":"IUBMB Life"},{"key":"10.1016\/j.biocel.2014.09.003_bib0315","doi-asserted-by":"crossref","first-page":"7474","DOI":"10.1021\/bi9700936","article-title":"Activation of the leukocyte NADPH oxidase subunit p47phox by protein kinase C. A phosphorylation-dependent change in the conformation of the C-terminal end of p47phox","volume":"36","author":"Park","year":"1997","journal-title":"Biochemistry"},{"key":"10.1016\/j.biocel.2014.09.003_bib0320","doi-asserted-by":"crossref","first-page":"1458","DOI":"10.1016\/j.clinthera.2013.07.421","article-title":"Evolving concepts: the negative effect of minimal hepatic encephalopathy and role for prophylaxis in patients with cirrhosis","volume":"35","author":"Prakash","year":"2013","journal-title":"Clin Ther"},{"key":"10.1016\/j.biocel.2014.09.003_bib0325","doi-asserted-by":"crossref","first-page":"2370","DOI":"10.1007\/s00330-013-2963-2","article-title":"Grey and white matter abnormalities in minimal hepatic encephalopathy: a study combining voxel-based morphometry and tract-based spatial statistics","volume":"23","author":"Qi","year":"2013","journal-title":"Eur Radiol"},{"key":"10.1016\/j.biocel.2014.09.003_bib0330","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1111\/j.1365-2362.1976.tb00533.x","article-title":"Plasma and brain amino acids in fulminant hepatic failure and their relationship to hepatic encephalopathy","volume":"6","author":"Record","year":"1976","journal-title":"Eur J Clin Invest"},{"key":"10.1016\/j.biocel.2014.09.003_bib0335","doi-asserted-by":"crossref","first-page":"27179","DOI":"10.1074\/jbc.M414361200","article-title":"Involvement of NADPH oxidase isoforms and Src family kinases in CD95-dependent hepatocyte apoptosis","volume":"280","author":"Reinehr","year":"2005","journal-title":"J Biol Chem"},{"key":"10.1016\/j.biocel.2014.09.003_bib0340","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1002\/glia.20504","article-title":"Hypoosmotic swelling and ammonia increase oxidative stress by NADPH oxidase in cultured astrocytes and vital brain slices","volume":"55","author":"Reinehr","year":"2007","journal-title":"Glia"},{"key":"10.1016\/j.biocel.2014.09.003_bib0350","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1096\/fj.01-0862fje","article-title":"Ammonia induces MK-801-sensitive nitration and phosphorylation of protein tyrosine residues in rat astrocytes","volume":"16","author":"Schliess","year":"2002","journal-title":"FASEB J"},{"key":"10.1016\/j.biocel.2014.09.003_bib0360","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1002\/glia.20019","article-title":"Hypoosmotic swelling increases protein tyrosine nitration in cultured rat astrocytes","volume":"47","author":"Schliess","year":"2004","journal-title":"Glia"},{"key":"10.1016\/j.biocel.2014.09.003_bib0375","doi-asserted-by":"crossref","first-page":"1871","DOI":"10.1093\/brain\/aws083","article-title":"Dopamine and performance in a reinforcement learning task: evidence from Parkinson's disease","volume":"135","author":"Shiner","year":"2012","journal-title":"Brain"},{"key":"10.1016\/j.biocel.2014.09.003_bib0380","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1007\/s12640-011-9269-4","article-title":"Alterations of blood brain barrier function in hyperammonemia: an overview","volume":"21","author":"Skowronska","year":"2012","journal-title":"Neurotox Res"},{"key":"10.1016\/j.biocel.2014.09.003_bib0390","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1111\/j.1365-2990.2006.00768.x","article-title":"The expression of nNOS, iNOS and nitrotyrosine is increased in the rat cerebral cortex in experimental hepatic encephalopathy","volume":"32","author":"Su\u00e1rez","year":"2006","journal-title":"Neuropathol Appl Neurobiol"},{"key":"10.1016\/j.biocel.2014.09.003_bib0395","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1007\/s11011-013-9405-3","article-title":"Cognitive assessment of patients with minimal hepatic encephalopathy in Brazil","volume":"28","author":"Torres","year":"2013","journal-title":"Metab Brain Dis"},{"key":"10.1016\/j.biocel.2014.09.003_bib0405","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1055\/s-2003-42644","article-title":"Pathogenesis of hepatic encephalopathy in acute liver failure","volume":"23","author":"Vaquero","year":"2003","journal-title":"Semin Liver Dis"},{"key":"10.1016\/j.biocel.2014.09.003_bib0410","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1006\/abio.1995.1079","article-title":"Sample pretreatment with nitrate reductase and glucose-6-phosphate dehydrogenase quantitatively reduces nitrate while avoiding interference by NADP+ when the Griess reaction is used to assay for nitrite","volume":"224","author":"Verdon","year":"1995","journal-title":"Anal Biochem"},{"key":"10.1016\/j.biocel.2014.09.003_bib0415","doi-asserted-by":"crossref","first-page":"1428","DOI":"10.1007\/s00018-002-8520-9","article-title":"The superoxide-generating NADPH oxidase: structural aspects and activation mechanism","volume":"59","author":"Vignais","year":"2002","journal-title":"Cell Mol Life Sci"},{"key":"10.1016\/j.biocel.2014.09.003_bib0420","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1023\/A:1011107607993","article-title":"Altered striatal dopamine D2 receptor density and dopamine transport in a patient with hepatic encephalopathy","volume":"15","author":"Weissenborn","year":"2000","journal-title":"Metab Brain Dis"},{"key":"10.1016\/j.biocel.2014.09.003_bib0425","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1016\/0306-4522(95)00462-9","article-title":"Inhibition of glutamine synthetase reduces ammonia-induced astrocyte swelling in rat","volume":"71","author":"Willard-Mack","year":"1996","journal-title":"Neuroscience"},{"key":"10.1016\/j.biocel.2014.09.003_bib0430","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.bbr.2005.03.026","article-title":"Implanted cannula-mediated repetitive administration of Abeta25-35 into the mouse cerebral ventricle effectively impairs spatial working memory","volume":"164","author":"Yamada","year":"2005","journal-title":"Behav Brain Res"},{"key":"10.1016\/j.biocel.2014.09.003_bib0435","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1002\/hep.1840120413","article-title":"Increased serotoninergic and noradrenergic activity in hepatic encephalopathy in rats with thioacetamide-induced acute liver failure","volume":"12","author":"Yurdaydin","year":"1990","journal-title":"Hepatology"}],"container-title":["The International Journal of Biochemistry &amp; Cell Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1357272514002854?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1357272514002854?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T06:55:15Z","timestamp":1761202515000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1357272514002854"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,10]]},"references-count":72,"alternative-id":["S1357272514002854"],"URL":"https:\/\/doi.org\/10.1016\/j.biocel.2014.09.003","relation":{},"ISSN":["1357-2725"],"issn-type":[{"type":"print","value":"1357-2725"}],"subject":[],"published":{"date-parts":[[2014,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Elevated dopamine induces minimal hepatic encephalopathy by activation of astrocytic NADPH oxidase and astrocytic protein tyrosine nitration","name":"articletitle","label":"Article Title"},{"value":"The International Journal of Biochemistry & Cell Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biocel.2014.09.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}