{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T11:01:43Z","timestamp":1773658903678,"version":"3.50.1"},"reference-count":63,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2010,5,1]],"date-time":"2010-05-01T00:00:00Z","timestamp":1272672000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochimie"],"published-print":{"date-parts":[[2010,5]]},"DOI":"10.1016\/j.biochi.2010.01.022","type":"journal-article","created":{"date-parts":[[2010,2,9]],"date-time":"2010-02-09T15:13:15Z","timestamp":1265728395000},"page":"545-554","source":"Crossref","is-referenced-by-count":34,"title":["DNA-hydrolyzing activity of IgG antibodies from the sera of patients with tick-borne encephalitis"],"prefix":"10.1016","volume":"92","author":[{"given":"Taisiya A.","family":"Parkhomenko","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valentina N.","family":"Buneva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ol'ga B.","family":"Tyshkevich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Igor I.","family":"Generalov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Boris M.","family":"Doronin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georgy A.","family":"Nevinsky","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.biochi.2010.01.022_bib1","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/0165-2478(88)90043-0","article-title":"Autoimmune diseases other than lupus share common anti-DNA idiotypes","volume":"17","author":"Shoenfeld","year":"1988","journal-title":"Immunol. Lett."},{"key":"10.1016\/j.biochi.2010.01.022_bib2","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1111\/j.1365-2249.1991.tb05775.x","article-title":"Analysis of antibodies to RNA in patients with systemic lupus erythematosus and other autoimmune rheumatic diseases","volume":"86","author":"Blanco","year":"1991","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.biochi.2010.01.022_bib3","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1111\/j.1365-2249.1994.tb06603.x","article-title":"Serological association of lupus autoantibodies to a limited functional domain of 28S ribosomal RNA and to the ribosomal proteins bound to the domain","volume":"98","author":"Sato","year":"1994","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.biochi.2010.01.022_bib4","first-page":"931","article-title":"Anti-TS1-RNA: characterization of novel antibodies against sequence-specific RNA by random RNA selection in patients with Sjogren's syndrome","volume":"29","author":"Hirokawa","year":"2002","journal-title":"J. Rheumatol."},{"key":"10.1016\/j.biochi.2010.01.022_bib5","first-page":"998","article-title":"Clinical significance of antibodies to TS1-RNA in patients with mixed connective tissue disease","volume":"30","author":"Ikeda","year":"2003","journal-title":"J. Rheumatol."},{"key":"10.1016\/j.biochi.2010.01.022_bib6","first-page":"513","article-title":"Antinucleosome antibodies and T-cell response in systemic lupus erythematosus","volume":"153","author":"Founel","year":"2002","journal-title":"Ann. Med. Interne (Paris)"},{"key":"10.1016\/j.biochi.2010.01.022_bib7","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/0008-8749(72)90060-3","article-title":"Antigen\u2013RNA interactions","volume":"5","author":"Gottieb","year":"1972","journal-title":"Cell. Immunol."},{"key":"10.1016\/j.biochi.2010.01.022_bib8","first-page":"37","article-title":"Lessons from a monoclonal antibody to double-stranded DNA","volume":"44","author":"Kubota","year":"1977","journal-title":"J.\u00a0Med. Dent. Sci."},{"key":"10.1016\/j.biochi.2010.01.022_bib9","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1006\/meth.1996.0381","article-title":"Monoclonal anti-DNA antibodies: structure, specificity, and biology","volume":"11","author":"Marion","year":"1997","journal-title":"Methods"},{"key":"10.1016\/j.biochi.2010.01.022_bib10","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1007\/BF00243760","article-title":"Ribonucleic acid in the immune response","volume":"20","author":"Mitsuhashi","year":"1978","journal-title":"Mol. Cell. Biochem."},{"key":"10.1016\/j.biochi.2010.01.022_bib11","first-page":"375","article-title":"Specific and natural antibody production during Salmonella typhimurium infection in genetically susceptible and resistant mice","volume":"79","author":"Matsiota-Bernard","year":"1993","journal-title":"Immunology"},{"key":"10.1016\/j.biochi.2010.01.022_bib12","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1046\/j.1365-2249.1996.15724.x","article-title":"Beneficial effect of Salmonella typhimurium infection and of immunoglobulins from S. typhimurium-infected mice on the autoimmune disease of (NZB\u00a0\u00d7\u00a0NZW) F1 mice","volume":"104","author":"Matsiota-Bernard","year":"1996","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.biochi.2010.01.022_bib13","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1002\/eji.1830240103","article-title":"Beneficial effect of polyclonal immunoglobulins from malaria-infected BALB\/c mice on the lupus-like syndrome of (NZB\u00a0\u00d7\u00a0NZW)F1 mice","volume":"24","author":"Hentati","year":"1994","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.biochi.2010.01.022_bib14","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1093\/intimm\/3.1.29","article-title":"Induction of high levels of IgG autoantibodies in mice infected with Plasmodium chabaudi","volume":"3","author":"Ternynck","year":"1991","journal-title":"Int. Immunol."},{"key":"10.1016\/j.biochi.2010.01.022_bib15","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1002\/jcla.1860070111","article-title":"Autoantibodies in the sera of Trypanosoma cruzi-infected individuals with or without clinical Chagas disease","volume":"7","author":"Unterkircher","year":"1993","journal-title":"J. Clin. Lab. Anal."},{"key":"10.1016\/j.biochi.2010.01.022_bib16","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1007\/s10875-007-9099-6","article-title":"Analyses of CD27(++) plasma cells in peripheral blood from patients with bacterial infections and patients with serum antinuclear antibodies","volume":"27","author":"Boekel","year":"2007","journal-title":"J. Clin. Immunol."},{"key":"10.1016\/j.biochi.2010.01.022_bib17","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1093\/intimm\/13.9.1099","article-title":"Molecular mimicry: anti-DNA antibodies may arise inadvertently as a response to antibodies generated to microorganisms","volume":"13","author":"Wun","year":"2001","journal-title":"Int. Immunol."},{"key":"10.1016\/j.biochi.2010.01.022_bib18","series-title":"Harrison's Principles of Internal Medicine","author":"Fauci","year":"2008"},{"key":"10.1016\/j.biochi.2010.01.022_bib19","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1038\/ni0901-762","article-title":"Multiple sclerosis: a two-stage disease","volume":"2","author":"Steinman","year":"2001","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.biochi.2010.01.022_bib20","series-title":"Catalytic Antibodies","first-page":"1","year":"2005"},{"key":"10.1016\/j.biochi.2010.01.022_bib21","series-title":"Protein\u2013Protein Interactions, a Molecular Cloning Manual, Cold Spring Harbor Lab","article-title":"Catalytic antibodies: new characters in the protein repertoire","author":"Nevinsky","year":"2002"},{"key":"10.1016\/j.biochi.2010.01.022_bib22","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/S0022-1759(02)00234-X","article-title":"Human catalytic RNA- and DNA-hydrolyzing antibodies","volume":"269","author":"Nevinsky","year":"2002","journal-title":"J. Immunol. Methods"},{"key":"10.1016\/j.biochi.2010.01.022_bib23","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1111\/j.1582-4934.2003.tb00227.x","article-title":"Catalytic antibodies in healthy humans and patients with autoimmune and viral diseases","volume":"7","author":"Nevinsky","year":"2003","journal-title":"J. Cell. Mol. Med."},{"key":"10.1016\/j.biochi.2010.01.022_bib24","series-title":"Catalytic Antibodies","first-page":"503","article-title":"Natural catalytic antibodies\u2013abzymes","author":"Nevinsky","year":"2005"},{"key":"10.1016\/j.biochi.2010.01.022_bib25","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1126\/science.1585181","article-title":"DNA hydrolyzing autoantibodies","volume":"256","author":"Shuster","year":"1992","journal-title":"Science"},{"key":"10.1016\/j.biochi.2010.01.022_bib26","first-page":"1358","article-title":"DNA- and RNA-hydrolyzing antibodies from the blood of patients with various forms of viral hepatitis","volume":"62","author":"Baranovsky","year":"1997","journal-title":"Biochemistry (Mosc.)"},{"key":"10.1016\/j.biochi.2010.01.022_bib27","first-page":"1239","article-title":"Polyclonal antibodies from blood and cerebrospinal fluid of patients with multiple sclerosis effectively hydrolyze DNA and RNA","volume":"63","author":"Baranovskii","year":"1998","journal-title":"Biochemistry (Mosc.)"},{"key":"10.1016\/j.biochi.2010.01.022_bib28","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1007\/BF02787705","article-title":"Mechanism and functional role of antibody catalysis","volume":"75","author":"Paul","year":"1998","journal-title":"Appl. Biochem. Biotechnol."},{"key":"10.1016\/j.biochi.2010.01.022_bib29","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1111\/j.1582-4934.2004.tb00325.x","article-title":"Hydrolysis of myelin basic protein by polyclonal catalytic IgGs from the sera of patients with multiple sclerosis","volume":"8","author":"Polosukhina","year":"2004","journal-title":"J. Cell. Mol. Med."},{"key":"10.1016\/j.biochi.2010.01.022_bib30","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.imlet.2005.10.018","article-title":"Metal-dependent hydrolysis of myelin basic protein by IgGs from the sera of patients with multiple sclerosis","volume":"103","author":"Polosukhina","year":"2006","journal-title":"Immunol. Lett."},{"key":"10.1016\/j.biochi.2010.01.022_bib31","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1073\/pnas.0509849103","article-title":"Autoantibodies to myelin basic protein catalyze site-specific degradation of their antigen","volume":"103","author":"Ponamorenko","year":"2006","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.biochi.2010.01.022_bib32","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1007\/BF02787708","article-title":"Novel functional activities of anti-DNA autoantibodies from sera of patients with lymphoproliferative and autoimmune diseases","volume":"75","author":"Kozyr","year":"1998","journal-title":"Appl. Biochem. Biotechnol."},{"key":"10.1016\/j.biochi.2010.01.022_bib33","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1385\/ABAB:83:1-3:85","article-title":"Does catalytic activity of Bence\u2013Jones proteins contribute to the pathogenesis of multiple myeloma?","volume":"83","author":"Sinohara","year":"2000","journal-title":"Appl. Biochem. Biotechnol."},{"key":"10.1016\/j.biochi.2010.01.022_bib34","doi-asserted-by":"crossref","first-page":"4109","DOI":"10.1073\/pnas.0500586102","article-title":"High levels of catalytic antibodies correlate with favorable outcome in sepsis","volume":"102","author":"Lacroix-Desmazes","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.biochi.2010.01.022_bib35","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1016\/j.biochi.2009.06.018","article-title":"HIV-1 integrase hydrolyzing antibodies from the sera of HIV-infected patients","volume":"9","author":"Baranova","year":"2009","journal-title":"Biochimie"},{"key":"10.1016\/j.biochi.2010.01.022_bib36","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1134\/S0006297906030047","article-title":"Proteolytic activity of IgG antibodies from blood of acquired immunodeficiency syndrome patients","volume":"71","author":"Odintsova","year":"2006","journal-title":"Biochemistry (Mosc.)"},{"key":"10.1016\/j.biochi.2010.01.022_bib37","first-page":"857","article-title":"DNA-hydrolyzing IgG antibodies from the blood of patients with acquired immune deficiency syndrome","volume":"40","author":"Odintsova","year":"2006","journal-title":"Mol. Biol. (Mosc.)"},{"key":"10.1016\/j.biochi.2010.01.022_bib38","doi-asserted-by":"crossref","first-page":"6738","DOI":"10.1016\/j.vaccine.2008.10.059","article-title":"Conference report of the 10th meeting of the international scientific working group on tick-borne encephalitis (ISW-TBE): combating tick-borne encephalitis: vaccination rates on the rise","volume":"26","author":"Kunze","year":"2008","journal-title":"Vaccine"},{"key":"10.1016\/j.biochi.2010.01.022_bib39","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1093\/oxfordjournals.jbchem.a133033","article-title":"Affinity chromatography of porcine pancreas deoxyribonuclease I on DNA-binding sepharose under non-digestive conditions, using its substrate-binding site","volume":"88","author":"Tanaka","year":"1980","journal-title":"J. Biochem. (Tokyo)"},{"key":"10.1016\/j.biochi.2010.01.022_bib40","doi-asserted-by":"crossref","first-page":"12588","DOI":"10.1016\/S0021-9258(19)86355-X","article-title":"The relationship between human serum and human pancreatic DNase I","volume":"254","author":"Love","year":"1979","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.biochi.2010.01.022_bib41","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1002\/jmr.300070203","article-title":"DNA recognition by DNase I","volume":"7","author":"Suck","year":"1994","journal-title":"J. Mol. Recognit."},{"key":"10.1016\/j.biochi.2010.01.022_bib42","series-title":"The Enzymes","author":"Bernardi","year":"1971"},{"key":"10.1016\/j.biochi.2010.01.022_bib43","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/S0165-2478(01)00185-7","article-title":"Catalytic heterogeneity of polyclonal DNA-hydrolyzing antibodies from the sera of patients with multiple sclerosis","volume":"76","author":"Baranovskii","year":"2001","journal-title":"Immunol. Lett."},{"key":"10.1016\/j.biochi.2010.01.022_bib44","first-page":"460","article-title":"Catalytic heterogeneity of polyclonal RNA-hydrolyzing IgM from sera of patients with lupus erythematosus","volume":"6","author":"Andrievskaia","year":"2000","journal-title":"Med. Sci. Monit."},{"key":"10.1016\/j.biochi.2010.01.022_bib45","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/S0165-2478(02)00006-8","article-title":"Catalytic diversity of polyclonal RNA-hydrolyzing IgG antibodies from the sera of patients with lupus erythematosus","volume":"81","author":"Andrievskaya","year":"2002","journal-title":"Immunol. Lett."},{"key":"10.1016\/j.biochi.2010.01.022_bib46","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1111\/j.1582-4934.2007.00048.x","article-title":"Formation of different abzymes in autoimmune-prone MRL-lpr\/lpr mice is associated with changes in colony formation of haematopoietic progenitors","volume":"11","author":"Andryushkova","year":"2007","journal-title":"J. Cell. Mol. Med."},{"key":"10.1016\/j.biochi.2010.01.022_bib47","series-title":"Enzyme Structure and Mechanism","author":"Fersht","year":"1985"},{"key":"10.1016\/j.biochi.2010.01.022_bib48","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1385\/ABAB:83:1-3:115","article-title":"Secretory immunoglobulin A from healthy human mothers' milk catalyzes nucleic acid hydrolysis","volume":"83","author":"Nevinsky","year":"2000","journal-title":"Appl. Biochem. Biotechnol."},{"key":"10.1016\/j.biochi.2010.01.022_bib49","doi-asserted-by":"crossref","first-page":"1499","DOI":"10.1016\/0161-5890(93)90458-N","article-title":"IgG auto- and polyreactivities of normal human sera","volume":"30","author":"Berneman","year":"1993","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.biochi.2010.01.022_bib50","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1016\/0952-7915(95)80053-0","article-title":"Natural autoantibodies","volume":"7","author":"Coutinho","year":"1995","journal-title":"Curr. Opin. Immunol."},{"key":"10.1016\/j.biochi.2010.01.022_bib51","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1002\/eji.1830230213","article-title":"Cross-reactions of anti-DNA autoantibodies with cell surface proteins","volume":"23","author":"Raz","year":"1993","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.biochi.2010.01.022_bib52","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1016\/j.bbapap.2007.05.006","article-title":"Activation of DNA-hydrolyzing antibodies from the sera of autoimmune-prone MRL-lpr\/lpr mice by different metal ions","volume":"1774","author":"Kuznetsova","year":"2007","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.biochi.2010.01.022_bib53","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1002\/jmr.890","article-title":"Immunization of rabbits with DNase I produces polyclonal antibodies with DNase and RNase activities","volume":"21","author":"Krasnorutskii","year":"2008","journal-title":"J.\u00a0Mol. Recognit."},{"key":"10.1016\/j.biochi.2010.01.022_bib54","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1093\/intimm\/dxn061","article-title":"Anti-RNase antibodies against pancreatic ribonuclease A hydrolyze RNA and DNA","volume":"20","year":"2008","journal-title":"Int. Immunol."},{"key":"10.1016\/j.biochi.2010.01.022_bib55","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1002\/jmr.906","article-title":"Antibodies against RNA hydrolyze RNA and DNA","volume":"21","author":"Krasnorutskii","year":"2008","journal-title":"J. Mol. Recognit."},{"key":"10.1016\/j.biochi.2010.01.022_bib56","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1134\/S0006297908110114","article-title":"Antibodies against DNA hydrolyze RNA and DNA","volume":"73","author":"Krasnorutskii","year":"2008","journal-title":"Biochemistry (Mosc.)"},{"key":"10.1016\/j.biochi.2010.01.022_bib57","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1093\/intimm\/dxp004","article-title":"Immunization of rabbits with DNase II leads to formation of polyclonal antibodies with DNase and RNase activities","volume":"21","author":"Krasnorutskii","year":"2009","journal-title":"Int. Immunol."},{"key":"10.1016\/j.biochi.2010.01.022_bib58","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1042\/bj3250465","article-title":"Rabbit DNase I: purification from urine, immunological and proteochemical characterization, nucleotide sequence, expression in tissues, relationships with other mammalian DNases I and phylogenetic analysis","volume":"325","author":"Yasuda","year":"1997","journal-title":"Biochem. J."},{"key":"10.1016\/j.biochi.2010.01.022_bib59","doi-asserted-by":"crossref","first-page":"3726","DOI":"10.1016\/S0021-9258(19)85765-4","article-title":"The effect of divalent cations on the mode of action of DNase I. The initial reaction products produced from covalently closed circular DNA","volume":"255","author":"Campbell","year":"1980","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.biochi.2010.01.022_bib60","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/S0022-1759(02)00233-8","article-title":"Evolution of catalytic antibody repertoire in autoimmune mice","volume":"269","author":"Nishi","year":"2002","journal-title":"J. Immunol. Methods"},{"key":"10.1016\/j.biochi.2010.01.022_bib61","doi-asserted-by":"crossref","first-page":"2145","DOI":"10.1073\/pnas.92.6.2145","article-title":"Unexpectedly high occurrence of catalytic antibodies in MRL\/lpr and SJL mice immunized with a transition-state analog: is there a linkage to autoimmunity?","volume":"92","author":"Tawfik","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.biochi.2010.01.022_bib62","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1073\/pnas.92.1.254","article-title":"Cleavage of supercoiled plasmid DNA by autoantibody Fab fragment: application of the flow linear dichroism technique","volume":"92","author":"Gololobov","year":"1995","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.biochi.2010.01.022_bib63","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1002\/jmr.743","article-title":"Casein-hydrolyzing activity of sIgA antibodies from human milk","volume":"18","author":"Odintsova","year":"2005","journal-title":"J. Mol. Recognit."}],"container-title":["Biochimie"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300908410000404?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300908410000404?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,10,22]],"date-time":"2021-10-22T14:07:30Z","timestamp":1634911650000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0300908410000404"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,5]]},"references-count":63,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2010,5]]}},"alternative-id":["S0300908410000404"],"URL":"https:\/\/doi.org\/10.1016\/j.biochi.2010.01.022","relation":{},"ISSN":["0300-9084"],"issn-type":[{"value":"0300-9084","type":"print"}],"subject":[],"published":{"date-parts":[[2010,5]]}}}