{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T00:22:31Z","timestamp":1791332551499,"version":"4.3.1"},"reference-count":77,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2012,10,1]],"date-time":"2012-10-01T00:00:00Z","timestamp":1349049600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochimie"],"published-print":{"date-parts":[[2012,10]]},"DOI":"10.1016\/j.biochi.2012.01.021","type":"journal-article","created":{"date-parts":[[2012,2,4]],"date-time":"2012-02-04T15:32:48Z","timestamp":1328369568000},"page":"2172-2179","source":"Crossref","is-referenced-by-count":22,"title":["Adiponectin and leptin in human severe insulin resistance \u2013 Diagnostic utility and biological insights"],"prefix":"10.1016","volume":"94","author":[{"given":"M.P.","family":"Groeneveld","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Huang-Doran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.K.","family":"Semple","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.biochi.2012.01.021_bib1","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1038\/27376","article-title":"Leptin and the regulation of body weight in mammals","volume":"395","author":"Friedman","year":"1998","journal-title":"Nature"},{"key":"10.1016\/j.biochi.2012.01.021_bib2","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1016\/0092-8674(95)90151-5","article-title":"Identification and expression cloning of a leptin receptor, OB-R","volume":"83","author":"Tartaglia","year":"1995","journal-title":"Cell"},{"key":"10.1016\/j.biochi.2012.01.021_bib3","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1038\/372425a0","article-title":"Positional cloning of the mouse obese gene and its human homologue","volume":"372","author":"Zhang","year":"1994","journal-title":"Nature"},{"key":"10.1016\/j.biochi.2012.01.021_bib4","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1038\/43185","article-title":"Congenital leptin deficiency is associated with severe early-onset obesity in humans","volume":"387","author":"Montague","year":"1997","journal-title":"Nature"},{"key":"10.1016\/j.biochi.2012.01.021_bib5","doi-asserted-by":"crossref","first-page":"6231","DOI":"10.1073\/pnas.93.13.6231","article-title":"Defective STAT signaling by the leptin receptor in diabetic mice","volume":"93","author":"Ghilardi","year":"1996","journal-title":"Proc. Natl. Acad. Sci. U.\u00a0S. A."},{"key":"10.1016\/j.biochi.2012.01.021_bib6","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1038\/32911","article-title":"A\u00a0mutation in the human leptin receptor gene causes obesity and pituitary dysfunction","volume":"392","author":"Clement","year":"1998","journal-title":"Nature"},{"key":"10.1016\/j.biochi.2012.01.021_bib7","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1056\/NEJMoa063988","article-title":"Clinical and molecular genetic spectrum of congenital deficiency of the leptin receptor","volume":"356","author":"Farooqi","year":"2007","journal-title":"N.\u00a0Engl. J. Med."},{"key":"10.1016\/j.biochi.2012.01.021_bib8","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1126\/science.271.5251.994","article-title":"Phenotypes of mouse diabetes and rat fatty due to mutations in the OB (leptin) receptor","volume":"271","author":"Chua","year":"1996","journal-title":"Science"},{"key":"10.1016\/j.biochi.2012.01.021_bib9","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1056\/NEJM199909163411204","article-title":"Effects of recombinant leptin therapy in a child with congenital leptin deficiency","volume":"341","author":"Farooqi","year":"1999","journal-title":"N.\u00a0Engl. J. Med."},{"key":"10.1016\/j.biochi.2012.01.021_bib10","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1172\/JCI0215693","article-title":"Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine\/metabolic dysfunction of human congenital leptin deficiency","volume":"110","author":"Farooqi","year":"2002","journal-title":"J.\u00a0Clin. Invest."},{"key":"10.1016\/j.biochi.2012.01.021_bib11","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1056\/NEJMoa012437","article-title":"Leptin-replacement therapy for lipodystrophy","volume":"346","author":"Oral","year":"2002","journal-title":"N.\u00a0Engl. J. Med."},{"key":"10.1016\/j.biochi.2012.01.021_bib12","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1126\/science.7624777","article-title":"Weight-reducing effects of the plasma protein encoded by the obese gene","volume":"269","author":"Halaas","year":"1995","journal-title":"Science"},{"key":"10.1016\/j.biochi.2012.01.021_bib13","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1006\/bbrc.1996.0587","article-title":"cDNA cloning and expression of a novel adipose specific collagen-like factor,\u00a0apM1 (AdiPose Most abundant Gene transcript 1)","volume":"221","author":"Maeda","year":"1996","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.biochi.2012.01.021_bib14","doi-asserted-by":"crossref","first-page":"1544","DOI":"10.1210\/jc.2009-2286","article-title":"Hypoadiponectinemia \u2013 cause or consequence of human \u201cinsulin resistance\u201d?","volume":"95","author":"Cook","year":"2010","journal-title":"J.\u00a0Clin. Endocrinol. Metab."},{"key":"10.1016\/j.biochi.2012.01.021_bib15","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1530\/eje.1.01978","article-title":"The metabolism of isoforms of human adiponectin: studies in human subjects and in experimental animals","volume":"153","author":"Peake","year":"2005","journal-title":"Eur. J. Endocrinol."},{"key":"10.1016\/j.biochi.2012.01.021_bib16","doi-asserted-by":"crossref","first-page":"1961","DOI":"10.2337\/db08-1750","article-title":"Systemic fate of the adipocyte-derived factor adiponectin","volume":"58","author":"Halberg","year":"2009","journal-title":"Diabetes"},{"key":"10.1016\/j.biochi.2012.01.021_bib17","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/j.biocel.2009.12.021","article-title":"Adiponectin \u2013 it's all about the modifications","volume":"42","author":"Simpson","year":"2010","journal-title":"Int.\u00a0J. Biochem. Cell Biol."},{"key":"10.1016\/j.biochi.2012.01.021_bib18","doi-asserted-by":"crossref","first-page":"2270","DOI":"10.1210\/en.2007-1561","article-title":"Plasma adiponectin complexes have distinct biochemical characteristics","volume":"149","author":"Schraw","year":"2008","journal-title":"Endocrinology"},{"key":"10.1016\/j.biochi.2012.01.021_bib19","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1038\/nature01705","article-title":"Cloning of adiponectin receptors that mediate antidiabetic metabolic effects","volume":"423","author":"Yamauchi","year":"2003","journal-title":"Nature"},{"key":"10.1016\/j.biochi.2012.01.021_bib20","doi-asserted-by":"crossref","first-page":"10308","DOI":"10.1073\/pnas.0403382101","article-title":"T-cadherin is a receptor for hexameric and high-molecular-weight forms of Acrp30\/adiponectin","volume":"101","author":"Hug","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.biochi.2012.01.021_bib21","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/j.cmet.2011.02.010","article-title":"Adiponectin enhances insulin sensitivity by increasing hepatic IRS-2 expression via a macrophage-derived IL-6-dependent pathway","volume":"13","author":"Awazawa","year":"2011","journal-title":"Cell Metab."},{"key":"10.1016\/j.biochi.2012.01.021_bib22","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1210\/er.2005-0005","article-title":"Adiponectin and adiponectin receptors","volume":"26","author":"Kadowaki","year":"2005","journal-title":"Endocr. Rev."},{"key":"10.1016\/j.biochi.2012.01.021_bib23","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1038\/nm.2277","article-title":"Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin","volume":"17","author":"Holland","year":"2011","journal-title":"Nat. Med."},{"key":"10.1016\/j.biochi.2012.01.021_bib24","doi-asserted-by":"crossref","first-page":"4955","DOI":"10.1093\/hmg\/ddq423","article-title":"Genome-wide association study for adiponectin levels in Filipino women identifies CDH13 and a novel uncommon haplotype at KNG1-ADIPOQ","volume":"19","author":"Wu","year":"2010","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.biochi.2012.01.021_bib25","doi-asserted-by":"crossref","first-page":"2417","DOI":"10.2337\/db10-1321","article-title":"A\u00a0genome-wide association study reveals a quantitative trait locus of adiponectin on CDH13 that predicts cardiometabolic outcomes","volume":"60","author":"Chung","year":"2011","journal-title":"Diabetes"},{"key":"10.1016\/j.biochi.2012.01.021_bib26","doi-asserted-by":"crossref","first-page":"1432","DOI":"10.1016\/j.amjcard.2011.06.068","article-title":"A\u00a0variant upstream of the CDH13 adiponectin receptor gene and metabolic syndrome in Swedes","volume":"108","author":"Fava","year":"2011","journal-title":"Am. J. Cardiol."},{"key":"10.1016\/j.biochi.2012.01.021_bib27","article-title":"CDH13 gene coding T-cadherin influences variations in plasma adiponectin levels in Japanese population","author":"Morisaki","year":"2011","journal-title":"Hum. Mutat."},{"key":"10.1016\/j.biochi.2012.01.021_bib28","doi-asserted-by":"crossref","first-page":"4342","DOI":"10.1172\/JCI43464","article-title":"T-cadherin is critical for adiponectin-mediated cardioprotection in mice","volume":"120","author":"Denzel","year":"2010","journal-title":"J.\u00a0Clin. Invest."},{"key":"10.1016\/j.biochi.2012.01.021_bib29","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1038\/90992","article-title":"The adipocyte-secreted protein Acrp30 enhances hepatic insulin action","volume":"7","author":"Berg","year":"2001","journal-title":"Nat. Med."},{"key":"10.1016\/j.biochi.2012.01.021_bib30","doi-asserted-by":"crossref","first-page":"587","DOI":"10.33549\/physiolres.931089","article-title":"Increased insulin sensitivity in patients with anorexia nervosa: the role of adipocytokines","volume":"56","author":"Dostalova","year":"2007","journal-title":"Physiol. Res."},{"key":"10.1016\/j.biochi.2012.01.021_bib31","doi-asserted-by":"crossref","first-page":"2046","DOI":"10.1210\/jc.2006-2855","article-title":"Relationships between serum adipokines, insulin levels, and bone density in girls with anorexia nervosa","volume":"92","author":"Misra","year":"2007","journal-title":"J.\u00a0Clin. Endocrinol. Metab."},{"key":"10.1016\/j.biochi.2012.01.021_bib32","doi-asserted-by":"crossref","first-page":"1843","DOI":"10.1210\/jc.2006-1683","article-title":"Modulation of adiponectin and leptin during refeeding of female anorexia nervosa patients","volume":"92","author":"Modan-Moses","year":"2007","journal-title":"J.\u00a0Clin. Endocrinol. Metab."},{"key":"10.1016\/j.biochi.2012.01.021_bib33","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1111\/j.1365-2265.2004.02128.x","article-title":"Abundance of adiponectin in the newborn","volume":"61","author":"Dunger","year":"2004","journal-title":"Clin. Endocrinol. (Oxf.)"},{"key":"10.1016\/j.biochi.2012.01.021_bib34","doi-asserted-by":"crossref","first-page":"5500","DOI":"10.1210\/jc.2004-0792","article-title":"Adiponectin levels in the first two years of life in a prospective cohort: relations with weight gain, leptin levels and insulin sensitivity","volume":"89","author":"Iniguez","year":"2004","journal-title":"J.\u00a0Clin. Endocrinol. Metab."},{"key":"10.1016\/j.biochi.2012.01.021_bib35","doi-asserted-by":"crossref","first-page":"4652","DOI":"10.1210\/jc.2002-020694","article-title":"Plasma adiponectin concentrations in children: relationships with obesity and insulinemia","volume":"87","author":"Stefan","year":"2002","journal-title":"J.\u00a0Clin. Endocrinol. Metab."},{"key":"10.1016\/j.biochi.2012.01.021_bib36","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1203\/00006450-197809000-00005","article-title":"The growth and development of fat cells in infancy","volume":"12","author":"Boulton","year":"1978","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.biochi.2012.01.021_bib37","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1007\/s12020-009-9278-8","article-title":"Adiponectin action from head to toe","volume":"37","author":"Brochu-Gaudreau","year":"2010","journal-title":"Endocrine"},{"key":"10.1016\/j.biochi.2012.01.021_bib38","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1172\/JCI0215001","article-title":"Leptin reverses insulin resistance and hepatic steatosis in patients with severe lipodystrophy","volume":"109","author":"Petersen","year":"2002","journal-title":"J.\u00a0Clin. Invest."},{"key":"10.1016\/j.biochi.2012.01.021_bib39","doi-asserted-by":"crossref","first-page":"2607","DOI":"10.1093\/hmg\/11.21.2607","article-title":"Single-nucleotide polymorphism haplotypes in the both proximal promoter and exon 3 of the APM1 gene modulate adipocyte-secreted adiponectin hormone levels and contribute to the genetic risk for type 2 diabetes in French Caucasians","volume":"11","author":"Vasseur","year":"2002","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.biochi.2012.01.021_bib40","doi-asserted-by":"crossref","first-page":"2325","DOI":"10.2337\/diabetes.51.7.2325","article-title":"Association of adiponectin mutation with type 2 diabetes: a candidate gene for the insulin resistance syndrome","volume":"51","author":"Kondo","year":"2002","journal-title":"Diabetes"},{"key":"10.1016\/j.biochi.2012.01.021_bib41","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1038\/sj.ijo.0801244","article-title":"Genomic structure and mutations in adipose-specific gene, adiponectin","volume":"24","author":"Takahashi","year":"2000","journal-title":"Int. J. Obes. Relat. Metab. Disord."},{"key":"10.1016\/j.biochi.2012.01.021_bib42","doi-asserted-by":"crossref","first-page":"3353","DOI":"10.2337\/db08-0700","article-title":"Common variants in the adiponectin gene (ADIPOQ) associated with plasma adiponectin levels, type 2 diabetes, and diabetes-related quantitative traits: the Framingham Offspring Study","volume":"57","author":"Hivert","year":"2008","journal-title":"Diabetes"},{"key":"10.1016\/j.biochi.2012.01.021_bib43","doi-asserted-by":"crossref","first-page":"536","DOI":"10.2337\/diabetes.51.2.536","article-title":"Genetic variation in the gene encoding adiponectin is associated with an increased risk of type 2 diabetes in the Japanese population","volume":"51","author":"Hara","year":"2002","journal-title":"Diabetes"},{"key":"10.1016\/j.biochi.2012.01.021_bib44","doi-asserted-by":"crossref","first-page":"e26792","DOI":"10.1371\/journal.pone.0026792","article-title":"Novel adiponectin variants identified in type 2 diabetic patients reveal multimerization and secretion defects","volume":"6","author":"Jungtrakoon","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.biochi.2012.01.021_bib45","doi-asserted-by":"crossref","first-page":"40352","DOI":"10.1074\/jbc.M300365200","article-title":"Impaired multimerization of human adiponectin mutants associated with diabetes. Molecular structure and multimer formation of adiponectin","volume":"278","author":"Waki","year":"2003","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.biochi.2012.01.021_bib46","doi-asserted-by":"crossref","first-page":"2303","DOI":"10.1007\/s00125-011-2202-9","article-title":"Associations between single-nucleotide polymorphisms (+45T\u00a0>\u00a0G,\u00a0+276G\u00a0>\u00a0T,\u00a0\u221211377C\u00a0>\u00a0G,\u00a0\u221211391G\u00a0>\u00a0A) of adiponectin gene and type 2 diabetes mellitus: a systematic review and meta-analysis","volume":"54","author":"Han","year":"2011","journal-title":"Diabetologia"},{"key":"10.1016\/j.biochi.2012.01.021_bib47","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1210\/er.2010-0020","article-title":"Genetic syndromes of severe insulin resistance","volume":"32","author":"Semple","year":"2011","journal-title":"Endocr. Rev."},{"key":"10.1016\/j.biochi.2012.01.021_bib48","doi-asserted-by":"crossref","first-page":"3219","DOI":"10.1210\/jc.2006-0166","article-title":"Elevated plasma adiponectin in humans with genetically defective insulin receptors","volume":"91","author":"Semple","year":"2006","journal-title":"J.\u00a0Clin. Endocrinol. Metab."},{"key":"10.1016\/j.biochi.2012.01.021_bib49","doi-asserted-by":"crossref","first-page":"1712","DOI":"10.2337\/db06-1665","article-title":"Paradoxical elevation of high-molecular weight adiponectin in acquired extreme insulin resistance due to insulin receptor antibodies","volume":"56","author":"Semple","year":"2007","journal-title":"Diabetes"},{"key":"10.1016\/j.biochi.2012.01.021_bib50","doi-asserted-by":"crossref","first-page":"e109","DOI":"10.2337\/dc07-1342","article-title":"Elevated plasma adiponectin and leptin levels in sisters with genetically defective insulin receptors","volume":"30","author":"Hattori","year":"2007","journal-title":"Diabetes Care"},{"key":"10.1016\/j.biochi.2012.01.021_bib51","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1210\/jc.2009-1824","article-title":"Higher adiponectin levels in patients with Berardinelli\u2013Seip congenital lipodystrophy due to seipin as compared with 1-acylglycerol-3-phosphate-o-acyltransferase-2 deficiency","volume":"95","author":"Antuna-Puente","year":"2010","journal-title":"J.\u00a0Clin. Endocrinol. Metab."},{"key":"10.1016\/j.biochi.2012.01.021_bib52","doi-asserted-by":"crossref","first-page":"977","DOI":"10.2337\/dc07-2194","article-title":"Plasma adiponectin as a marker of insulin receptor dysfunction: clinical utility in severe insulin resistance","volume":"31","author":"Semple","year":"2008","journal-title":"Diabetes Care"},{"key":"10.1016\/j.biochi.2012.01.021_bib53","doi-asserted-by":"crossref","first-page":"1969","DOI":"10.2337\/db07-0127","article-title":"Adiponectin resistance exacerbates insulin resistance in insulin receptor transgenic\/knockout mice","volume":"56","author":"Lin","year":"2007","journal-title":"Diabetes"},{"key":"10.1016\/j.biochi.2012.01.021_bib54","doi-asserted-by":"crossref","first-page":"5433","DOI":"10.1210\/jc.2003-030835","article-title":"Phenotypic heterogeneity in body fat distribution in patients with congenital generalized lipodystrophy caused by mutations in the AGPAT2 or seipin genes","volume":"88","author":"Simha","year":"2003","journal-title":"J.\u00a0Clin. Endocrinol. Metab."},{"key":"10.1016\/j.biochi.2012.01.021_bib55","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/S1534-5807(02)00199-5","article-title":"Adipose tissue selective insulin receptor knockout protects against obesity and obesity-related glucose intolerance","volume":"3","author":"Bluher","year":"2002","journal-title":"Dev. Cell"},{"key":"10.1016\/j.biochi.2012.01.021_bib56","doi-asserted-by":"crossref","first-page":"ra87","DOI":"10.1126\/scisignal.2001173","article-title":"A\u00a0kinase-independent role for unoccupied insulin and IGF-1 receptors in the control of apoptosis","volume":"3","author":"Boucher","year":"2010","journal-title":"Sci. Signal."},{"key":"10.1016\/j.biochi.2012.01.021_bib57","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1006\/bbrc.2001.6307","article-title":"Hormonal regulation of adiponectin gene expression in 3T3-L1 adipocytes","volume":"290","author":"Fasshauer","year":"2002","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.biochi.2012.01.021_bib58","doi-asserted-by":"crossref","first-page":"1636","DOI":"10.1016\/j.metabol.2005.07.002","article-title":"Inhibition of the phosphatidylinositol 3\u2032-kinase signaling pathway leads to decreased insulin-stimulated adiponectin secretion from 3T3-L1 adipocytes","volume":"54","author":"Pereira","year":"2005","journal-title":"Metabolism"},{"key":"10.1016\/j.biochi.2012.01.021_bib59","doi-asserted-by":"crossref","first-page":"31891","DOI":"10.1074\/jbc.M404569200","article-title":"Intrinsic heterogeneity in adipose tissue of fat-specific insulin receptor knock-out mice is associated with differences in patterns of gene expression","volume":"279","author":"Bluher","year":"2004","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.biochi.2012.01.021_bib60","doi-asserted-by":"crossref","first-page":"E741","DOI":"10.1152\/ajpendo.00419.2004","article-title":"Abdominal adipose tissue cytokine gene expression: relationship to obesity and metabolic risk factors","volume":"288","author":"You","year":"2005","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"10.1016\/j.biochi.2012.01.021_bib61","doi-asserted-by":"crossref","first-page":"1779","DOI":"10.2337\/diabetes.52.7.1779","article-title":"Adiponectin expression from human adipose tissue: relation to obesity, insulin resistance, and tumor necrosis factor-alpha expression","volume":"52","author":"Kern","year":"2003","journal-title":"Diabetes"},{"key":"10.1016\/j.biochi.2012.01.021_bib62","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1038\/oby.2005.74","article-title":"Regulation of adiponectin expression in human adipocytes: effects of adiposity, glucocorticoids, and tumor necrosis factor alpha","volume":"13","author":"Degawa-Yamauchi","year":"2005","journal-title":"Obes. Res."},{"key":"10.1016\/j.biochi.2012.01.021_bib63","doi-asserted-by":"crossref","first-page":"1118","DOI":"10.1381\/096089206778392149","article-title":"Gene expression of leptin, resistin, and adiponectin in the white adipose tissue of obese patients with non-alcoholic fatty liver disease and insulin resistance","volume":"16","author":"Baranova","year":"2006","journal-title":"Obes. Surg."},{"key":"10.1016\/j.biochi.2012.01.021_bib64","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1083\/jcb.146.3.609","article-title":"Two compartments for insulin-stimulated exocytosis in 3T3-L1 adipocytes defined by endogenous ACRP30 and GLUT4","volume":"146","author":"Bogan","year":"1999","journal-title":"J.\u00a0Cell Biol."},{"key":"10.1016\/j.biochi.2012.01.021_bib65","doi-asserted-by":"crossref","first-page":"1655","DOI":"10.1016\/j.metabol.2008.07.020","article-title":"Regulation of adiponectin secretion by insulin and amino acids in 3T3-L1 adipocytes","volume":"57","author":"Blumer","year":"2008","journal-title":"Metabolism"},{"key":"10.1016\/j.biochi.2012.01.021_bib66","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1055\/s-2007-990275","article-title":"Interfering effects of insulin, growth hormone and glucose on adipokine secretion","volume":"116","author":"Wolfing","year":"2008","journal-title":"Exp. Clin. Endocrinol. Diabetes"},{"key":"10.1016\/j.biochi.2012.01.021_bib67","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.phrs.2006.01.013","article-title":"Vanadium and insulin increase adiponectin production in 3T3-L1 adipocytes","volume":"54","author":"Seale","year":"2006","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.biochi.2012.01.021_bib68","doi-asserted-by":"crossref","first-page":"3716","DOI":"10.1128\/MCB.00931-06","article-title":"Secretion of the adipocyte-specific secretory protein adiponectin critically depends on thiol-mediated protein retention","volume":"27","author":"Wang","year":"2007","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.biochi.2012.01.021_bib69","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1210\/en.2003-1068","article-title":"A\u00a0transgenic mouse with a deletion in the collagenous domain of adiponectin displays elevated circulating adiponectin and improved insulin sensitivity","volume":"145","author":"Combs","year":"2004","journal-title":"Endocrinology"},{"key":"10.1016\/j.biochi.2012.01.021_bib70","doi-asserted-by":"crossref","first-page":"2174","DOI":"10.2337\/db07-0185","article-title":"Selective downregulation of the high molecular weight form of adiponectin in hyperinsulinemia and in type 2 diabetes: differential regulation from nondiabetic subjects","volume":"56","author":"Basu","year":"2007","journal-title":"Diabetes"},{"key":"10.1016\/j.biochi.2012.01.021_bib71","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/S1097-2765(05)00010-9","article-title":"Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob\/ob mice","volume":"6","author":"Shimomura","year":"2000","journal-title":"Mol. Cell"},{"key":"10.1016\/j.biochi.2012.01.021_bib72","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.cmet.2007.12.009","article-title":"Selective versus total insulin resistance: a pathogenic paradox","volume":"7","author":"Brown","year":"2008","journal-title":"Cell Metab."},{"key":"10.1016\/j.biochi.2012.01.021_bib73","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.cmet.2007.11.013","article-title":"Hepatic insulin resistance is sufficient to\u00a0produce dyslipidemia and susceptibility to atherosclerosis","volume":"7","author":"Biddinger","year":"2008","journal-title":"Cell Metab."},{"key":"10.1016\/j.biochi.2012.01.021_bib74","first-page":"315","article-title":"Postreceptor insulin resistance contributes to human dyslipidemia and hepatic steatosis","volume":"119","author":"Semple","year":"2009","journal-title":"J.\u00a0Clin. Invest."},{"key":"10.1016\/j.biochi.2012.01.021_bib75","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1111\/j.1467-789X.2009.00623.x","article-title":"Subcutaneous and visceral adipose tissue: structural and functional differences","volume":"11","author":"Ibrahim","year":"2010","journal-title":"Obes. Rev."},{"key":"10.1016\/j.biochi.2012.01.021_bib76","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1038\/ijo.2009.286","article-title":"Gluteofemoral body fat as a determinant of metabolic health","volume":"34","author":"Manolopoulos","year":"2010","journal-title":"Int. J. Obes. (Lond.)"},{"key":"10.1016\/j.biochi.2012.01.021_bib77","doi-asserted-by":"crossref","first-page":"2515","DOI":"10.1007\/s00125-011-2252-z","article-title":"Adipose tissue mass and location affect circulating adiponectin levels","volume":"54","author":"Turer","year":"2011","journal-title":"Diabetologia"}],"container-title":["Biochimie"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300908412000399?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300908412000399?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,12,27]],"date-time":"2021-12-27T22:32:49Z","timestamp":1640644369000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0300908412000399"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,10]]},"references-count":77,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2012,10]]}},"alternative-id":["S0300908412000399"],"URL":"https:\/\/doi.org\/10.1016\/j.biochi.2012.01.021","relation":{},"ISSN":["0300-9084"],"issn-type":[{"value":"0300-9084","type":"print"}],"subject":[],"published":{"date-parts":[[2012,10]]}}}