{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T19:27:45Z","timestamp":1792783665907,"version":"4.5.0"},"reference-count":207,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,6,1]],"date-time":"2016-06-01T00:00:00Z","timestamp":1464739200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001677","name":"Inserm (Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale)","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001677","id-type":"DOI","asserted-by":"publisher"}]},{"name":"ANR-Carina","award":["ANR-12-BSV1-0016-01"],"award-info":[{"award-number":["ANR-12-BSV1-0016-01"]}]},{"name":"Universit\u00e9 Paul Sabatier Toulouse-3"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochimie"],"published-print":{"date-parts":[[2016,6]]},"DOI":"10.1016\/j.biochi.2015.12.014","type":"journal-article","created":{"date-parts":[[2015,12,22]],"date-time":"2015-12-22T02:25:28Z","timestamp":1450751128000},"page":"281-296","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":102,"special_numbering":"C","title":["Oxidative theory of atherosclerosis and antioxidants"],"prefix":"10.1016","volume":"125","author":[{"given":"R.","family":"Salvayre","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Negre-Salvayre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Camar\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.biochi.2015.12.014_bib1","first-page":"731","article-title":"The natural history of atherosclerosis; comparison of the early aortic lesions in New Orleans, Guatemala, and Costa Rica","volume":"34","author":"Strong","year":"1958","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.biochi.2015.12.014_bib2","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1111\/j.1749-6632.1968.tb53846.x","article-title":"The geographic pathology of atherosclerosis","volume":"149","author":"McGill","year":"1968","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.biochi.2015.12.014_bib3","first-page":"27","article-title":"Description and microscopic findings of two Egyptian mummies","volume":"9","author":"Czermak","year":"1852","journal-title":"Meet. Acad. Sci."},{"key":"10.1016\/j.biochi.2015.12.014_bib4","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1002\/path.1700150403","article-title":"On arterial lesions found in Egyptian mummies (1580 bc\u2013535 ad)","volume":"16","author":"Ruffer","year":"1911","journal-title":"J.\u00a0Pathol. Bacteriol."},{"key":"10.1016\/j.biochi.2015.12.014_bib5","doi-asserted-by":"crossref","first-page":"2091","DOI":"10.1001\/jama.2009.1641","article-title":"Computed tomographic assessment of atherosclerosis in ancient Egyptian mummies","volume":"302","author":"Allam","year":"2009","journal-title":"JAMA"},{"issue":"Suppl.\u00a01","key":"10.1016\/j.biochi.2015.12.014_bib6","first-page":"17","article-title":"Changes in components and structure of atherosclerotic lesions developing from childhood to middle age in coronary arteries","volume":"89","author":"Stary","year":"1994","journal-title":"Basic Res. Cardiol."},{"key":"10.1016\/j.biochi.2015.12.014_bib7","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1038\/362801a0","article-title":"The pathogenesis of atherosclerosis: a perspective for the 1990s","volume":"362","author":"Ross","year":"1993","journal-title":"Nature"},{"key":"10.1016\/j.biochi.2015.12.014_bib8","doi-asserted-by":"crossref","first-page":"2126","DOI":"10.1161\/01.CIR.90.4.2126","article-title":"Mechanisms leading to myocardial infarction: insights from studies of vascular biology","volume":"90","author":"Fuster","year":"1994","journal-title":"Circulation"},{"key":"10.1016\/j.biochi.2015.12.014_bib9","doi-asserted-by":"crossref","first-page":"2680","DOI":"10.1172\/JCI119813","article-title":"Fatty streak formation occurs in human fetal aortas and is greatly enhanced by maternal hypercholesterolemia. Intimal accumulation of LDL and its oxidation precede monocyte recruitment into early atherosclerotic lesions","volume":"100","author":"Napoli","year":"1997","journal-title":"J.\u00a0Clin. Invest."},{"issue":"5 Suppl.","key":"10.1016\/j.biochi.2015.12.014_bib10","doi-asserted-by":"crossref","first-page":"1307S","DOI":"10.1093\/ajcn\/72.5.1307s","article-title":"Origin of atherosclerosis in childhood and adolescence","volume":"72","author":"McGill","year":"2000","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.biochi.2015.12.014_bib11","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1038\/35025203","article-title":"Atherosclerosis","volume":"407","author":"Lusis","year":"2000","journal-title":"Nature"},{"key":"10.1016\/j.biochi.2015.12.014_bib12","doi-asserted-by":"crossref","first-page":"3481","DOI":"10.1161\/CIRCULATIONAHA.105.537878","article-title":"Pathophysiology of coronary artery disease","volume":"111","author":"Libby","year":"2005","journal-title":"Circulation"},{"key":"10.1016\/j.biochi.2015.12.014_bib13","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1093\/eurheartj\/ehs411","article-title":"Update on acute coronary syndromes: the pathologists' view","volume":"34","author":"Falk","year":"2013","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.biochi.2015.12.014_bib14","first-page":"1385","article-title":"Two thousand years of historical study on the words atheroma, atheromatosis, atherosclerosis, arteriosclerosis","volume":"176","author":"Cottet","year":"1992","journal-title":"Bull. Acad. Natl. Med."},{"key":"10.1016\/j.biochi.2015.12.014_bib15","series-title":"Opuscula Pathologica","first-page":"124","author":"von Haller","year":"1755"},{"key":"10.1016\/j.biochi.2015.12.014_bib16","series-title":"Engraving Intended to Illustrate Some of the Diseases of the Arteries","first-page":"5","author":"Hogson","year":"1815"},{"key":"10.1016\/j.biochi.2015.12.014_bib17","series-title":"Trait\u00e9 d'anatomie pathologique g\u00e9n\u00e9rale et sp\u00e9ciale","author":"Lebert","year":"1857"},{"key":"10.1016\/j.biochi.2015.12.014_bib18","series-title":"La pathologie cellulaire bas\u00e9e sur l'\u00e9tude physiologique et pathologique des tissus","first-page":"336","author":"Virchow","year":"1868"},{"key":"10.1016\/j.biochi.2015.12.014_bib19","series-title":"Trait\u00e9s D\u2019anatomie Pathologique","first-page":"550","author":"Lobstein","year":"1833"},{"key":"10.1016\/j.biochi.2015.12.014_bib20","first-page":"23","article-title":"\u00dcber arteriosklerose (athero-sklerose)","volume":"21","author":"Marchand","year":"1904","journal-title":"Verh. Kongr. Inn. Med."},{"key":"10.1016\/j.biochi.2015.12.014_bib21","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.1194\/jlr.R400003-JLR200","article-title":"Thematic review series: the pathogenesis of atherosclerosis. An interpretive history of the cholesterol controversy: part I","volume":"45","author":"Steinberg","year":"2004","journal-title":"J.\u00a0Lipid Res."},{"key":"10.1016\/j.biochi.2015.12.014_bib22","series-title":"Recherches chimiques sur les corps gras d'origine animale","first-page":"pp.153","author":"Chevreul","year":"1823"},{"key":"10.1016\/j.biochi.2015.12.014_bib23","series-title":"The Pathological Anatomy of the Human Body","author":"Vogel","year":"1847"},{"key":"10.1016\/j.biochi.2015.12.014_bib24","first-page":"1","article-title":"Influence de la nourriture animale sur l\u2019organisme des lapins","volume":"20","author":"Ignatowski","year":"1908","journal-title":"Arch. Med. Exp. Anat. Pathol."},{"key":"10.1016\/j.biochi.2015.12.014_bib25","series-title":"Du role de la cholesterine dans le d\u00e9veloppement de l'art\u00e9rioscl\u00e9rose et de l'ath\u00e9rome","author":"Lemoine","year":"1911"},{"key":"10.1016\/j.biochi.2015.12.014_bib26","first-page":"1","article-title":"\u00dcber experimentelle Cholesterinsteatose und ihre Bedeutung f\u00fcr die Entstehlung einiger pathologischer Prozesse","volume":"24","author":"Anitchkow","year":"1913","journal-title":"Zentrbl. Allg. Pathol. Pathol. Anat."},{"key":"10.1016\/j.biochi.2015.12.014_bib27","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1007\/BF01972927","article-title":"\u00dcber die Ablagerung von fettartigen Stoffen in den Organen","volume":"212","author":"Wesselkin","year":"1913","journal-title":"Virchows Arch. Pathol. Anat. Physiol. Klin. Med"},{"key":"10.1016\/j.biochi.2015.12.014_bib28","first-page":"1079","article-title":"Sur la presence de depots de cholesterine dans les tuniques arterielles sclero-atheromateuses","volume":"151","author":"Lemoine","year":"1910","journal-title":"Compt. Rend. Acad. Sci. Paris"},{"key":"10.1016\/j.biochi.2015.12.014_bib29","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1515\/bchm2.1910.67.2.174","article-title":"\u00dcber der Gehalt normaler und atheromatoser Aorten and Cholesterol und Cholesterinester","volume":"67","author":"Windaus","year":"1910","journal-title":"Hoppe Seyler\u2019s Z. Physiol. Chem."},{"key":"10.1016\/j.biochi.2015.12.014_bib30","doi-asserted-by":"crossref","first-page":"589S","DOI":"10.1093\/jn\/125.3_Suppl.589S","article-title":"Dietary proteins, cholesterol and atherosclerosis. A review of the early history","volume":"125","author":"Kritchevsky","year":"1995","journal-title":"J.\u00a0Nutr."},{"key":"10.1016\/j.biochi.2015.12.014_bib31","first-page":"268","article-title":"Recherches sur les phosphoaminolipides et les sterides du serum et du plasma sanguins","volume":"11","author":"Macheboeuf","year":"1929","journal-title":"Bull. Soc. Chim. Biol."},{"key":"10.1016\/j.biochi.2015.12.014_bib32","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/S0021-9258(19)56153-1","article-title":"Lipids and polysaccharides in electrophoretically separated blood serum proteins","volume":"137","author":"Blix","year":"1941","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.biochi.2015.12.014_bib33","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1021\/j150451a011","article-title":"On a LDL appearing in normal human plasma","volume":"51","author":"Pedersen","year":"1945","journal-title":"J.\u00a0Phys. Colloid Chem."},{"key":"10.1016\/j.biochi.2015.12.014_bib34","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1021\/ja01207a034","article-title":"Preparation and properties of serum and plasma lipoproteins. IV. A system for the separation into fractions of the protein and lipoprotein components of biological tissues and fluids","volume":"68","author":"Cohn","year":"1946","journal-title":"J.\u00a0Am. Chem. Soc."},{"key":"10.1016\/j.biochi.2015.12.014_bib35","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1172\/JCI103182","article-title":"The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum","volume":"34","author":"Havel","year":"1955","journal-title":"J.\u00a0Clin. Invest."},{"issue":"1967","key":"10.1016\/j.biochi.2015.12.014_bib36","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1056\/NEJM196701052760107","article-title":"Fat transport in lipoproteins - an integrated approach to mechanisms and disorders","volume":"276","author":"Fredrickson","year":"1967","journal-title":"N.\u00a0Engl. J. Med."},{"key":"10.1016\/j.biochi.2015.12.014_bib37","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1007\/BF02282101","article-title":"\u00dcber Xanthoma multiplex planum, tuberosurn, mollusciforme","volume":"116","author":"Lehzen","year":"1989","journal-title":"Arch. Pathol. Anat. Physiol."},{"key":"10.1016\/j.biochi.2015.12.014_bib38","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.1055\/s-0028-1135664","article-title":"Zur Struktur und Genese der symptomatischen Xanthome","volume":"34","author":"Pinkus","year":"1908","journal-title":"Deutsch. Med. Wochenschr."},{"key":"10.1016\/j.biochi.2015.12.014_bib39","first-page":"675","article-title":"Angina pectoris in hereditary xanthornatosis","volume":"64","author":"Muller","year":"1939","journal-title":"Arch. Htem. Med."},{"key":"10.1016\/j.biochi.2015.12.014_bib40","doi-asserted-by":"crossref","first-page":"671","DOI":"10.7326\/0003-4819-29-4-671","article-title":"Essential familial hypercholesterolemia","volume":"29","author":"Wilkinson","year":"1948","journal-title":"Ann. Intern. Med."},{"key":"10.1016\/j.biochi.2015.12.014_bib41","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1016\/0002-9343(51)90046-0","article-title":"Hypercholesterolemia with predisposition to atherosclerosis: an inborn error of lipid metabolism","volume":"11","author":"Adlersberg","year":"1951","journal-title":"Am. J. Med."},{"issue":"1950","key":"10.1016\/j.biochi.2015.12.014_bib42","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1126\/science.111.2877.166","article-title":"The role of lipids and lipoproteins in atherosclerosis","volume":"111","author":"Gofman","year":"1950","journal-title":"Science"},{"key":"10.1016\/j.biochi.2015.12.014_bib43","doi-asserted-by":"crossref","first-page":"33","DOI":"10.7326\/0003-4819-55-1-33","article-title":"Factors of risk in the development of coronary heart disease - six year follow-up experience. The Framingham Study","volume":"55","author":"Kannel","year":"1961","journal-title":"Ann. Intern. Med."},{"key":"10.1016\/j.biochi.2015.12.014_bib44","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1038\/nrcardio.2014.26","article-title":"Epidemiological studies of CHD and the evolution of preventive cardiology","volume":"11","author":"Wong","year":"2014","journal-title":"Nat. Rev. Cardiol."},{"key":"10.1016\/j.biochi.2015.12.014_bib45","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1146\/annurev.bi.46.070177.004341","article-title":"The LDL pathway and its relation to atherosclerosis","volume":"46","author":"Goldstein","year":"1977","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.biochi.2015.12.014_bib46","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1146\/annurev.bi.52.070183.001255","article-title":"Lipoprotein metabolism in the macrophage: implications for cholesterol deposition in atherosclerosis","volume":"52","author":"Brown","year":"1983","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.biochi.2015.12.014_bib47","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.cell.2015.01.036","article-title":"A\u00a0century of cholesterol and coronaries: from plaques to genes to statins","volume":"161","author":"Goldstein","year":"2015","journal-title":"Cell"},{"key":"10.1016\/j.biochi.2015.12.014_bib48","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1038\/157584a0","article-title":"Biological action of radiations","volume":"157","author":"Weiss","year":"1946","journal-title":"Nature"},{"key":"10.1016\/j.biochi.2015.12.014_bib49","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1038\/162615a0","article-title":"Hydrogen peroxide and the indirect effect of ionizing radiations","volume":"162","author":"Alpert","year":"1948","journal-title":"Nature"},{"key":"10.1016\/j.biochi.2015.12.014_bib50","series-title":"The Chemistry of Free Radicals","author":"Waters","year":"1946"},{"key":"10.1016\/j.biochi.2015.12.014_bib51","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1042\/bj0400139","article-title":"Toxic effects of oxygen and of hydrogen peroxide on brain metabolism","volume":"40","author":"Mann","year":"1946","journal-title":"Biochem. J."},{"key":"10.1016\/j.biochi.2015.12.014_bib52","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1038\/165847a0","article-title":"Degradation of deoxyribonucleic acid by free radicals","volume":"165","author":"Butler","year":"1950","journal-title":"Nature"},{"key":"10.1016\/j.biochi.2015.12.014_bib53","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1093\/geronj\/11.3.298","article-title":"Aging: a theory based on free radical and radiation chemistry","volume":"11","author":"Harman","year":"1956","journal-title":"J.\u00a0Gerontol."},{"key":"10.1016\/j.biochi.2015.12.014_bib54","series-title":"Free Radicals in Biology and Medicine","author":"Halliwell","year":"2007"},{"key":"10.1016\/j.biochi.2015.12.014_bib55","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/0891-5849(91)90192-6","article-title":"Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes","volume":"11","author":"Esterbauer","year":"1991","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.biochi.2015.12.014_bib56","doi-asserted-by":"crossref","first-page":"1708","DOI":"10.1016\/S0891-5849(00)00228-8","article-title":"Glycoxidation and lipoxidation in atherogenesis","volume":"28","author":"Baynes","year":"2000","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.biochi.2015.12.014_bib57","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1038\/sj.bjp.0707395","article-title":"Advanced lipid peroxidation end products in oxidative damage to proteins. Potential role in diseases and therapeutic prospects for the inhibitors","volume":"153","author":"Negre-Salvayre","year":"2008","journal-title":"Br. J. Pharmacol."},{"issue":"Suppl.\u00a01","key":"10.1016\/j.biochi.2015.12.014_bib58","doi-asserted-by":"crossref","first-page":"3","DOI":"10.3109\/10715762.2013.815348","article-title":"Advanced glycoxidation and lipoxidation end products (AGEs and ALEs): an overview of their mechanisms of formation","volume":"47","author":"Vistoli","year":"2013","journal-title":"Free Radic. Res."},{"key":"10.1016\/j.biochi.2015.12.014_bib59","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.3109\/10715762.2010.498478","article-title":"Pathological aspects of lipid peroxidation","volume":"44","author":"Negre-Salvayre","year":"2010","journal-title":"Free Radic. Res."},{"key":"10.1016\/j.biochi.2015.12.014_bib60","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/0005-2760(86)90016-0","article-title":"Modification of human LDL by the lipid peroxidation product 4-hydroxynonenal","volume":"875","author":"J\u00fcrgens","year":"1986","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.biochi.2015.12.014_bib61","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.redox.2012.12.005","article-title":"Redox-derived damage-associated molecular patterns: ligand function of lipid peroxidation adducts","volume":"1","author":"Uchida","year":"2013","journal-title":"Redox Biol."},{"key":"10.1016\/j.biochi.2015.12.014_bib62","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.redox.2013.01.006","article-title":"Lipofuscin: formation, effects and role of macroautophagy","volume":"1","author":"H\u00f6hn","year":"2013","journal-title":"Redox Biol."},{"key":"10.1016\/j.biochi.2015.12.014_bib63","first-page":"395","article-title":"'Ceroid' pigment in human tissues","volume":"22","author":"Papenheimer","year":"1946","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.biochi.2015.12.014_bib64","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1007\/BF02168696","article-title":"The occurrence of peroxidized lipids in atheromatous human aortas","volume":"7","author":"Glavind","year":"1951","journal-title":"Experientia"},{"key":"10.1016\/j.biochi.2015.12.014_bib65","first-page":"50","article-title":"Peroxides as a factor of atherosclerosis","volume":"28","author":"Iwakami","year":"1965","journal-title":"Nagoya J. Med. Sci."},{"key":"10.1016\/j.biochi.2015.12.014_bib66","first-page":"23","article-title":"Lipid peroxides and arteriosclerosis","volume":"16","author":"Lankin","year":"1976","journal-title":"Kardiologiia"},{"key":"10.1016\/j.biochi.2015.12.014_bib67","doi-asserted-by":"crossref","first-page":"6499","DOI":"10.1073\/pnas.78.10.6499","article-title":"Enhanced macrophage degradation of LDL previously incubated with cultured endothelial cells: recognition by receptors for acetylated LDL","volume":"78","author":"Henriksen","year":"1981","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.biochi.2015.12.014_bib68","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1161\/01.ATV.3.3.215","article-title":"Lipoprotein oxidation and lipoprotein-induced cytotoxicity","volume":"3","author":"Hessler","year":"1983","journal-title":"Arteriosclerosis"},{"key":"10.1016\/j.biochi.2015.12.014_bib69","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1021\/tx00014a001","article-title":"Biochemical, structural, and functional properties of oxidized LDL","volume":"3","author":"Esterbauer","year":"1990","journal-title":"Chem. Res. Toxicol."},{"key":"10.1016\/j.biochi.2015.12.014_bib70","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.mam.2009.02.003","article-title":"Cholesterol oxidation products in the vascular remodeling due to atherosclerosis","volume":"30","author":"Poli","year":"2009","journal-title":"Mol. Asp. Med."},{"key":"10.1016\/j.biochi.2015.12.014_bib71","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1152\/physrev.00047.2003","article-title":"Role of oxidative modifications in atherosclerosis","volume":"84","author":"Stocker","year":"2004","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.biochi.2015.12.014_bib72","doi-asserted-by":"crossref","first-page":"1890","DOI":"10.1172\/JCI111609","article-title":"Iron and copper promote modification of LDL by human arterial smooth muscle cells in culture","volume":"84","author":"Heinecke","year":"1984","journal-title":"J.\u00a0Clin. Invest."},{"key":"10.1016\/j.biochi.2015.12.014_bib73","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1161\/01.ATV.4.4.357","article-title":"Endothelial and smooth muscle cells alter LDL in\u00a0vitro by free radical oxidation","volume":"4","author":"Morel","year":"1984","journal-title":"Arteriosclerosis"},{"key":"10.1016\/j.biochi.2015.12.014_bib74","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1016\/S0022-2275(20)38493-5","article-title":"Enzymatic modification of LDL by purified lipoxygenase plus phospholipase A2 mimics cell-mediated oxidative modification","volume":"29","author":"Sparrow","year":"1988","journal-title":"J.\u00a0Lipid Res."},{"key":"10.1016\/j.biochi.2015.12.014_bib75","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1016\/0891-5849(95)02173-6","article-title":"The role of oxidized lipoproteins in atherogenesis","volume":"20","author":"Berliner","year":"1996","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.biochi.2015.12.014_bib76","first-page":"915","article-title":"Beyond cholesterol. Modifications of LDL that increase its atherogenicity","volume":"320","author":"Steinberg","year":"1989","journal-title":"N.\u00a0Engl. J. Med."},{"key":"10.1016\/j.biochi.2015.12.014_bib77","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1080\/10408369891234282","article-title":"The role of adhesion molecules in atherosclerosis","volume":"35","author":"Chia","year":"1998","journal-title":"Crit. Rev. Clin. Lab. Sci."},{"key":"10.1016\/j.biochi.2015.12.014_bib78","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1073\/pnas.87.3.904","article-title":"Oxidized LDL induces differentiation and adhesion of human monocytes and the monocytic cell line U937","volume":"87","author":"Frosteg\u00e5rd","year":"1990","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.biochi.2015.12.014_bib79","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1038\/344254a0","article-title":"Induction of endothelial cell expression of granulocyte and macrophage colony-stimulating factors by modified LDL","volume":"344","author":"Rajavashisth","year":"1990","journal-title":"Nature"},{"key":"10.1016\/j.biochi.2015.12.014_bib80","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/0891-5849(88)90070-6","article-title":"Lipid peroxidation and endothelial cell injury: implications in atherosclerosis","volume":"4","author":"Hennig","year":"1988","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.biochi.2015.12.014_bib81","doi-asserted-by":"crossref","first-page":"2214","DOI":"10.1073\/pnas.77.4.2214","article-title":"Malondialdehyde alteration of LDL leads to cholesteryl ester accumulation in human monocyte-macrophages","volume":"77","author":"Fogelman","year":"1980","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.biochi.2015.12.014_bib82","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1161\/01.ATV.9.4.538","article-title":"Modification of LDL with 4-hydroxynonenal induces uptake by macrophages","volume":"9","author":"Hoff","year":"1989","journal-title":"Arteriosclerosis"},{"key":"10.1016\/j.biochi.2015.12.014_bib83","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1126\/science.2455346","article-title":"Malondialdehyde-altered protein occurs in atheroma of Watanabe heritable hyperlipidemic rabbits","volume":"241","author":"Haberland","year":"1988","journal-title":"Science"},{"key":"10.1016\/j.biochi.2015.12.014_bib84","doi-asserted-by":"crossref","first-page":"1689","DOI":"10.1161\/01.ATV.13.11.1689","article-title":"Immunostaining of human autopsy aortas with antibodies to modified apolipoprotein B and apoprotein(a)","volume":"13","author":"J\u00fcrgens","year":"1993","journal-title":"Arterioscler. Thromb."},{"key":"10.1016\/j.biochi.2015.12.014_bib85","doi-asserted-by":"crossref","first-page":"361","DOI":"10.3109\/00365517909106120","article-title":"Injury to human endothelial cells in culture induced by LDL","volume":"39","author":"Henriksen","year":"1979","journal-title":"Scand. J. Clin. Lab. Invest."},{"key":"10.1016\/j.biochi.2015.12.014_bib86","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/0021-9150(79)90166-7","article-title":"LDL-induced cytotoxicity and its inhibition by HDL in human smooth muscle and endothelial cells in culture","volume":"32","author":"Hessler","year":"1979","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.biochi.2015.12.014_bib87","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1096\/fj.02-0293fje","article-title":"Mildly oxidized LDL particle subspecies are distinct in their capacity to induce apoptosis in endothelial cells: role of lipid hydroperoxides","volume":"17","author":"Kontush","year":"2003","journal-title":"FASEB J."},{"key":"10.1016\/j.biochi.2015.12.014_bib88","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1126\/science.7352277","article-title":"Angiotoxicity of oxygenated sterols and possible precursors","volume":"207","author":"Imai","year":"1980","journal-title":"Science"},{"key":"10.1016\/j.biochi.2015.12.014_bib89","doi-asserted-by":"crossref","first-page":"1866","DOI":"10.1172\/JCI118232","article-title":"In\u00a0vitro cell injury by oxidized LDL involves lipid hydroperoxide-induced formation of alkoxyl, lipid, and peroxyl radicals","volume":"96","author":"Coffey","year":"1995","journal-title":"J.\u00a0Clin. Invest."},{"key":"10.1016\/j.biochi.2015.12.014_bib90","doi-asserted-by":"crossref","first-page":"1887","DOI":"10.1111\/jcmm.12561","article-title":"Foam cell-derived 4-hydroxynonenal induces endothelial cell senescence in a TXNIP-dependent manner","volume":"19","author":"Riahi","year":"2015","journal-title":"J.\u00a0Cell. Mol. Med."},{"key":"10.1016\/j.biochi.2015.12.014_bib91","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/0005-2760(90)90124-G","article-title":"UV-treated lipoproteins as a model system for the study of the biological effects of lipid peroxides on cultured cells. II. Uptake and cytotoxicity of UV-treated LDL on lymphoid cell lines","volume":"1045","author":"Negre-Salvayre","year":"1990","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.biochi.2015.12.014_bib92","doi-asserted-by":"crossref","first-page":"12633","DOI":"10.1074\/jbc.275.17.12633","article-title":"Oxidized LDL binding to LOX-1 in endothelial cells induces the activation of NF-kappaB through an increased production of intracellular reactive oxygen species","volume":"275","author":"Cominacini","year":"2000","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.biochi.2015.12.014_bib93","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1016\/S0022-2275(20)41181-2","article-title":"Biochemical and cytotoxic characteristics of an in\u00a0vivo circulating oxidized LDL","volume":"35","author":"Hodis","year":"1994","journal-title":"J.\u00a0Lipid Res."},{"key":"10.1016\/j.biochi.2015.12.014_bib94","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1002\/jcp.1041300302","article-title":"Toxicity of oxidized LDL to cultured fibroblasts is selective for S phase of the cell cycle","volume":"130","author":"Kosugi","year":"1987","journal-title":"J.\u00a0Cell. Physiol."},{"key":"10.1016\/j.biochi.2015.12.014_bib95","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/0014-5793(92)80101-L","article-title":"A\u00a0delayed and sustained rise of cytosolic calcium is elicited by oxidized LDL in cultured bovine aortic endothelial cells","volume":"299","author":"N\u00e8gre-Salvayre","year":"1992","journal-title":"FEBS Lett."},{"key":"10.1016\/j.biochi.2015.12.014_bib96","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1096\/fasebj.8.13.7926374","article-title":"Necrosis and apoptosis induced by oxidized LDL occur through two calcium-dependent pathways in lymphoblastoid cells","volume":"8","author":"Escargueil-Blanc","year":"1994","journal-title":"FASEB J."},{"issue":"8B","key":"10.1016\/j.biochi.2015.12.014_bib97","doi-asserted-by":"crossref","first-page":"1620","DOI":"10.1111\/j.1582-4934.2008.00593.x","article-title":"TRPC1 is regulated by caveolin-1 and is involved in oxidized LDL-induced apoptosis of vascular smooth muscle cells","volume":"13","author":"Ingueneau","year":"2009","journal-title":"J.\u00a0Cell. Mol. Med."},{"key":"10.1016\/j.biochi.2015.12.014_bib98","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1042\/bj20021955","article-title":"Oxidized LDL induces calpain-dependent cell death and ubiquitination of caspase 3 in HMEC-1","volume":"374","author":"P\u00f6rn-Ares","year":"2003","journal-title":"Biochem. J."},{"key":"10.1016\/j.biochi.2015.12.014_bib99","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1161\/01.ATV.0000154359.60886.33","article-title":"Two distinct calcium-dependent mitochondrial pathways are involved in oxidized LDL-induced apoptosis","volume":"25","author":"Vindis","year":"2005","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.biochi.2015.12.014_bib100","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1096\/fasebj.13.3.485","article-title":"Bcl-2 alters the balance between apoptosis and necrosis, but does not prevent cell death induced by oxidized LDL","volume":"13","author":"Meilhac","year":"1999","journal-title":"FASEB J."},{"issue":"2001","key":"10.1016\/j.biochi.2015.12.014_bib101","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1097\/00041433-200110000-00008","article-title":"Mechanisms of oxysterol-induced apoptosis","volume":"12","author":"Panini","year":"2001","journal-title":"Curr. Opin. Lipidol."},{"key":"10.1016\/j.biochi.2015.12.014_bib102","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/S1050-1738(01)00106-2","article-title":"Oxidized LDL-induced injury and apoptosis in atherosclerosis. Potential roles for oxysterols","volume":"11","author":"Colles","year":"2001","journal-title":"Trends Cardiovasc. Med."},{"key":"10.1016\/j.biochi.2015.12.014_bib103","doi-asserted-by":"crossref","first-page":"1682","DOI":"10.1172\/JCI3531","article-title":"Oxidized LDL activates fas-mediated endothelial cell apoptosis","volume":"102","author":"Sata","year":"1998","journal-title":"J.\u00a0Clin. Investig."},{"key":"10.1016\/j.biochi.2015.12.014_bib104","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/S1388-1981(02)00343-8","article-title":"Oxidized low-density lipoprotein-induced apoptosis","volume":"1585","author":"Salvayre","year":"2002","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.biochi.2015.12.014_bib105","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1055\/s-0037-1616240","article-title":"Apoptosis as a determinant of atherothrombosis","volume":"86","author":"Tedgui","year":"2001","journal-title":"Thromb. Haemost."},{"key":"10.1016\/j.biochi.2015.12.014_bib106","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1172\/JCI117409","article-title":"Genetic evidence for a common pathway mediating oxidative stress, inflammatory gene induction, and aortic fatty streak formation in mice","volume":"94","author":"Liao","year":"1994","journal-title":"J.\u00a0Clin. Investig."},{"key":"10.1016\/j.biochi.2015.12.014_bib107","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1161\/CIRCRESAHA.111.256859","article-title":"Role of phospholipid oxidation products in atherosclerosis","volume":"111","author":"Lee","year":"2012","journal-title":"Circ. Res."},{"key":"10.1016\/j.biochi.2015.12.014_bib108","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1080\/10715760410001665244","article-title":"Dual role of oxidized LDL on the NF-kappaB signaling pathway","volume":"38","author":"Robbesyn","year":"2004","journal-title":"Free Radic. Res."},{"key":"10.1016\/j.biochi.2015.12.014_bib109","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.freeradbiomed.2008.10.024","article-title":"Activation of transcription factors and gene expression by oxidized LDL","volume":"46","author":"Mazi\u00e8re","year":"2009","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.biochi.2015.12.014_bib110","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1161\/hc0902.104353","article-title":"Inflammation and atherosclerosis","volume":"105","author":"Libby","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.biochi.2015.12.014_bib111","doi-asserted-by":"crossref","first-page":"1372","DOI":"10.1073\/pnas.86.4.1372","article-title":"LDL undergoes oxidative modification in\u00a0vivo","volume":"86","author":"Palinski","year":"1989","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.biochi.2015.12.014_bib112","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1042\/BJ20111029","article-title":"Identification of 4-HNE-histidine adducts that serve as ligands for human LOX-1","volume":"442","author":"Kumano-Kuramochi","year":"2012","journal-title":"Biochem. J."},{"key":"10.1016\/j.biochi.2015.12.014_bib113","first-page":"798","article-title":"Post-traumatic dynamic changes in the antibody titer against oxidized LDL","volume":"112","author":"Wildburger","year":"2000","journal-title":"Wien. Klin. Wochenschr."},{"key":"10.1016\/j.biochi.2015.12.014_bib114","doi-asserted-by":"crossref","first-page":"743","DOI":"10.5551\/jat.19281","article-title":"Pathogenic role of modified LDL antibodies and immune complexes in atherosclerosis","volume":"20","author":"Lopes-Virella","year":"2013","journal-title":"J.\u00a0Atheroscler. Thromb."},{"key":"10.1016\/j.biochi.2015.12.014_bib115","doi-asserted-by":"crossref","DOI":"10.1161\/ATVBAHA.107.152272","article-title":"Small concentrations of oxLDL induce capillary tube formation from endothelial cells via LOX-1-dependent redox-sensitive pathway","volume":"27","author":"Dandapat","year":"2007","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.biochi.2015.12.014_bib116","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1111\/bph.12897","article-title":"Oxidized LDL-induced angiogenesis involves sphingosine 1-phosphate: prevention by anti-S1P antibody","volume":"172","author":"Camar\u00e9","year":"2015","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.biochi.2015.12.014_bib117","doi-asserted-by":"crossref","first-page":"e0123971","DOI":"10.1371\/journal.pone.0123971","article-title":"The biphasic effects of oxidized-LDL on the vasculogenic function of endothelial progenitor cells","volume":"10","author":"Lin","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.biochi.2015.12.014_bib118","doi-asserted-by":"crossref","first-page":"2245","DOI":"10.1161\/CIRCULATIONAHA.105.578955","article-title":"Neovascularization in human atherosclerosis","volume":"113","author":"Moreno","year":"2006","journal-title":"Circulation"},{"key":"10.1016\/j.biochi.2015.12.014_bib119","doi-asserted-by":"crossref","first-page":"1813","DOI":"10.1161\/CIRCULATIONAHA.105.535294","article-title":"Role of angiogenesis in cardiovascular disease: a critical appraisal","volume":"112","author":"Khurana","year":"2005","journal-title":"Circulation"},{"key":"10.1016\/j.biochi.2015.12.014_bib120","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/0014-5793(90)80857-F","article-title":"Oxidized LDL is chemotactic for arterial smooth muscle cells in culture","volume":"277","author":"Autio","year":"1990","journal-title":"FEBS Lett."},{"key":"10.1016\/j.biochi.2015.12.014_bib121","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1007\/BF00229586","article-title":"Role of oxidized human plasma LDL in atherosclerosis: effects on smooth muscle cell proliferation","volume":"111","author":"Chatterjee","year":"1992","journal-title":"Mol. Cell. Biochem."},{"key":"10.1016\/j.biochi.2015.12.014_bib122","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1042\/bj3091015","article-title":"Proliferative and cytotoxic effects of mildly oxidized LDL on vascular smooth-muscle cells","volume":"309","author":"Aug\u00e9","year":"1995","journal-title":"Biochem. J."},{"key":"10.1016\/j.biochi.2015.12.014_bib123","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1161\/01.ATV.12.9.1099","article-title":"Native and oxidized LDL enhances production of PDGF AA and the surface expression of PDGF receptors in cultured human smooth muscle cells","volume":"12","author":"Stiko-Rahm","year":"1992","journal-title":"Arterioscler. Thromb."},{"key":"10.1016\/j.biochi.2015.12.014_bib124","doi-asserted-by":"crossref","first-page":"1814","DOI":"10.1161\/hc4001.097179","article-title":"Mildly oxidized LDL induces activation of PDGF beta-receptor pathway","volume":"104","author":"Escargueil-Blanc","year":"2001","journal-title":"Circulation"},{"key":"10.1016\/j.biochi.2015.12.014_bib125","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1161\/01.RES.0000216288.93234.c3","article-title":"Desensitization of PDGF receptor-beta by oxidized lipids in vascular cells and atherosclerotic lesions: prevention by aldehyde scavengers","volume":"98","author":"Vindis","year":"2006","journal-title":"Circ. Res."},{"key":"10.1016\/j.biochi.2015.12.014_bib126","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/S0098-2997(03)00020-7","article-title":"Oxidized LDL and 4-hydroxynonenal modulate tyrosine kinase receptor activity","volume":"24","author":"Negre-Salvayre","year":"2003","journal-title":"Mol. Asp. Med."},{"key":"10.1016\/j.biochi.2015.12.014_bib127","doi-asserted-by":"crossref","first-page":"2005","DOI":"10.1016\/S0022-2275(20)41118-6","article-title":"Oxidized LDL-mediated activation of phospholipase D in smooth muscle cells: a possible role in cell proliferation and atherogenesis","volume":"36","author":"Natarajan","year":"1995","journal-title":"J.\u00a0Lipid Res."},{"key":"10.1016\/j.biochi.2015.12.014_bib128","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1093\/glycob\/6.3.303","article-title":"Oxidized LDL stimulates aortic smooth muscle cell proliferation","volume":"6","author":"Chatterjee","year":"1996","journal-title":"Glycobiology"},{"key":"10.1016\/j.biochi.2015.12.014_bib129","doi-asserted-by":"crossref","first-page":"19251","DOI":"10.1074\/jbc.271.32.19251","article-title":"The sphingomyelin-ceramide signaling pathway is involved in oxidized LDL-induced cell proliferation","volume":"271","author":"Aug\u00e9","year":"1996","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.biochi.2015.12.014_bib130","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/S0163-7827(00)00007-2","article-title":"Sphingomyelin metabolites in vascular cell signaling and atherogenesis","volume":"39","author":"Aug\u00e9","year":"2000","journal-title":"Prog. Lipid Res."},{"key":"10.1016\/j.biochi.2015.12.014_bib131","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/0021-9150(95)05515-X","article-title":"Oxidized LDL stimulates collagen production in cultured arterial smooth muscle cells","volume":"116","author":"Jimi","year":"1995","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.biochi.2015.12.014_bib132","doi-asserted-by":"crossref","first-page":"2640","DOI":"10.1161\/01.ATV.19.11.2640","article-title":"Oxidized LDL stimulates MMP1 expression in human vascular endothelial cells","volume":"19","author":"Huang","year":"1999","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.biochi.2015.12.014_bib133","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1161\/01.CIR.99.8.993","article-title":"Oxidized LDL regulates MMP-9 and its tissue inhibitor in human monocyte-derived macrophages","volume":"99","author":"Xu","year":"1999","journal-title":"Circulation"},{"issue":"Suppl.\u00a01","key":"10.1016\/j.biochi.2015.12.014_bib134","first-page":"59","article-title":"Extracellular matrix degrading metalloproteinases in the pathogenesis of arteriosclerosis","volume":"89","author":"Newby","year":"1994","journal-title":"Basic Res. Cardiol."},{"key":"10.1016\/j.biochi.2015.12.014_bib135","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1097\/00041433-199810000-00005","article-title":"TIPs and MMPs in atherosclerosis","volume":"9","author":"George","year":"1998","journal-title":"Curr. Opin. Lipidol."},{"key":"10.1016\/j.biochi.2015.12.014_bib136","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1161\/01.CIR.0000136995.83451.1D","article-title":"Role for MMP2 in oxidized LDL-induced activation of the sphingomyelin\/ceramide pathway and smooth muscle cell proliferation","volume":"110","author":"Aug\u00e9","year":"2004","journal-title":"Circulation"},{"key":"10.1016\/j.biochi.2015.12.014_bib137","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.redox.2014.12.008","article-title":"Elastin aging and lipid oxidation products in human aorta","volume":"4","author":"Zarkovic","year":"2015","journal-title":"Redox Biol."},{"key":"10.1016\/j.biochi.2015.12.014_bib138","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1111\/j.1365-2796.2008.01947.x","article-title":"From vulnerable plaque to atherothrombosis","volume":"263","author":"Thim","year":"2008","journal-title":"J.\u00a0Intern. Med."},{"issue":"Suppl.\u00a01","key":"10.1016\/j.biochi.2015.12.014_bib139","doi-asserted-by":"crossref","first-page":"S34","DOI":"10.1160\/THS10-11-0717","article-title":"Update on lipids, inflammation and atherothrombosis","volume":"105","author":"Badimon","year":"2011","journal-title":"Thromb. Haemost."},{"key":"10.1016\/j.biochi.2015.12.014_bib140","doi-asserted-by":"crossref","first-page":"H852","DOI":"10.1152\/ajpheart.00015.2005","article-title":"Oxidized LDL induces mitochondrially associated reactive oxygen\/nitrogen species formation in endothelial cells","volume":"289","author":"Zmijewski","year":"2005","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.biochi.2015.12.014_bib141","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1002\/jcb.1198","article-title":"Multiple role of reactive oxygen species in the arterial wall","volume":"82","author":"Napoli","year":"2001","journal-title":"J.\u00a0Cell. Biochem."},{"key":"10.1016\/j.biochi.2015.12.014_bib142","doi-asserted-by":"crossref","first-page":"1364","DOI":"10.1161\/CIRCRESAHA.111.243972","article-title":"Biochemistry, physiology, and pathophysiology of NADPH oxidases in the cardiovascular system","volume":"110","author":"Lass\u00e8gue","year":"2012","journal-title":"Circ. Res."},{"issue":"3A","key":"10.1016\/j.biochi.2015.12.014_bib143","doi-asserted-by":"crossref","first-page":"7A","DOI":"10.1016\/S0002-9149(02)03144-2","article-title":"Role of oxidative stress in atherosclerosis","volume":"91","author":"Harrison","year":"2003","journal-title":"Am. J. Cardiol."},{"key":"10.1016\/j.biochi.2015.12.014_bib144","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1007\/s00424-009-0765-9","article-title":"Cellular signaling and NO production","volume":"459","author":"Michel","year":"2010","journal-title":"Pflugers Arch."},{"key":"10.1016\/j.biochi.2015.12.014_bib145","first-page":"488","article-title":"LDL are carriers for lipid peroxides and inhibit prostacyclin (PGI2) biosynthesis in arteries","volume":"7","author":"Szczeklik","year":"1980","journal-title":"Artery"},{"key":"10.1016\/j.biochi.2015.12.014_bib146","first-page":"601","article-title":"Minimally oxidized LDL induces tissue factor expression in cultured human endothelial cells","volume":"138","author":"Drake","year":"1991","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.biochi.2015.12.014_bib147","doi-asserted-by":"crossref","first-page":"e70533","DOI":"10.1371\/journal.pone.0070533","article-title":"Electronegative LDL increases CRP expression in vascular endothelial cells through the LOX-1 receptor","volume":"8","author":"Chu","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.biochi.2015.12.014_bib148","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1161\/01.RES.73.2.335","article-title":"Transferable lipids in oxidized LDL stimulate plasminogen activator inhibitor-1 and inhibit tPA release from endothelial cells","volume":"73","author":"Kugiyama","year":"1993","journal-title":"Circ. Res."},{"key":"10.1016\/j.biochi.2015.12.014_bib149","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/0021-9150(89)90094-4","article-title":"Platelet activation by oxidatively modified LDL","volume":"76","author":"Ardlie","year":"1989","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.biochi.2015.12.014_bib150","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/0049-3848(89)90145-X","article-title":"Modified forms of LDL affect platelet aggregation in\u00a0vitro","volume":"53","author":"Aviram","year":"1989","journal-title":"Thromb. Res."},{"key":"10.1016\/j.biochi.2015.12.014_bib151","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1089\/ars.2009.2733","article-title":"Oxidized LDL: diversity, patterns of recognition, and pathophysiology","volume":"13","author":"Levitan","year":"2010","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.biochi.2015.12.014_bib152","doi-asserted-by":"crossref","first-page":"2143","DOI":"10.1016\/S0022-2275(20)32089-7","article-title":"Oxidants and antioxidants in atherogenesis. An appraisal","volume":"40","author":"Parthasarathy","year":"1999","journal-title":"J.\u00a0Lipid Res."},{"key":"10.1016\/j.biochi.2015.12.014_bib153","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1042\/bst0320134","article-title":"Lipid oxidation in atherogenesis: an overview","volume":"32","author":"Jessup","year":"2004","journal-title":"Biochem. Soc. Trans."},{"key":"10.1016\/j.biochi.2015.12.014_bib154","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/j.plipres.2006.02.003","article-title":"Inflammation and immune regulation by 12\/15-lipoxygenases","volume":"45","author":"K\u00fchn","year":"2006","journal-title":"Prog. Lipid Res."},{"key":"10.1016\/j.biochi.2015.12.014_bib155","doi-asserted-by":"crossref","first-page":"2129","DOI":"10.1016\/j.jacc.2009.09.009","article-title":"Leducq Transatlantic Network on Atherothrombosis. Inflammation in atherosclerosis: from pathophysiology to practice","volume":"54","author":"Libby","year":"2009","journal-title":"J.\u00a0Am. Coll. Cardiol."},{"key":"10.1016\/j.biochi.2015.12.014_bib156","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/j.redox.2013.01.014","article-title":"Teaching the basics of redox biology to medical and graduate students: oxidants, antioxidants and disease mechanisms","volume":"1","author":"Kalyanaraman","year":"2013","journal-title":"Redox Biol."},{"key":"10.1016\/j.biochi.2015.12.014_bib157","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1089\/ars.2012.4599","article-title":"Thioredoxins, glutaredoxins, and peroxiredoxins - Molecular mechanisms and health significance: from cofactors to antioxidants to redox signaling","volume":"19","author":"Hanschmann","year":"2013","journal-title":"Antioxid. Redox Signal."},{"issue":"Suppl.\u00a05","key":"10.1016\/j.biochi.2015.12.014_bib158","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1289\/ehp.98106s51219","article-title":"The nature of antioxidant defense mechanisms: a lesson from transgenic studies","volume":"106","author":"Ho","year":"1998","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.biochi.2015.12.014_bib159","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1007\/978-1-60327-029-8_24","article-title":"Oxidized LDL","volume":"610","author":"Parthasarathy","year":"2010","journal-title":"Methods Mol. Biol."},{"issue":"Suppl.\u00a0E","key":"10.1016\/j.biochi.2015.12.014_bib160","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1093\/eurheartj\/11.suppl_E.83","article-title":"Oxidative modification of LDL: comparison between cell-mediated and copper-mediated modification","volume":"11","author":"Parthasarathy","year":"1990","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.biochi.2015.12.014_bib161","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/0891-5849(92)90181-F","article-title":"The role of lipid peroxidation and antioxidants in oxidative modification of LDL","volume":"13","author":"Esterbauer","year":"1992","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.biochi.2015.12.014_bib162","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/0891-5849(95)00006-J","article-title":"Alpha-Tocopherol and trolox block the early intracellular events (TBARS and calcium rises) elicited by oxidized LDL in cultured endothelial cells","volume":"19","author":"Mabile","year":"1995","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.biochi.2015.12.014_bib163","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1016\/j.freeradbiomed.2006.07.006","article-title":"Antioxidant and cytoprotective properties of HDL in vascular cells","volume":"41","author":"Negre-Salvayre","year":"2006","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.biochi.2015.12.014_bib164","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1038\/cdd.2008.36","article-title":"Oxygen-regulated protein-150 prevents calcium homeostasis deregulation and apoptosis induced by oxidized LDL in vascular cells","volume":"15","author":"Sanson","year":"2008","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.biochi.2015.12.014_bib165","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1172\/JCI117374","article-title":"Alpha-tocopherol inhibits agonist-induced monocytic cell adhesion to cultured human endothelial cells","volume":"94","author":"Faruqi","year":"1994","journal-title":"J.\u00a0Clin. Invest."},{"key":"10.1016\/j.biochi.2015.12.014_bib166","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1196\/annals.1331.009","article-title":"Vitamin E mediates cell signaling and regulation of gene expression","volume":"1031","author":"Azzi","year":"2004","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.biochi.2015.12.014_bib167","doi-asserted-by":"crossref","first-page":"63","DOI":"10.3109\/10715769709097785","article-title":"Antioxidant activity of phytoestrogenic isoflavones","volume":"26","author":"Ruiz-Larrea","year":"1997","journal-title":"Free Radic. Res."},{"key":"10.1016\/j.biochi.2015.12.014_bib168","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1016\/j.freeradbiomed.2012.05.027","article-title":"Actions of \u201cantioxidants\u201d in the protection against atherosclerosis","volume":"53","author":"L\u00f6nn","year":"2012","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.biochi.2015.12.014_bib169","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.1089\/ars.2011.3999","article-title":"Superoxide dismutases: role in redox signaling, vascular function, and diseases","volume":"15","author":"Fukai","year":"2011","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.biochi.2015.12.014_bib170","doi-asserted-by":"crossref","first-page":"e69193","DOI":"10.1371\/journal.pone.0069193","article-title":"T\u00a0he modified selenenyl amide, M-hydroxy ebselen, attenuates diabetic nephropathy and diabetes-associated atherosclerosis in ApoE\/GPx1 double knockout mice","volume":"8","author":"Tan","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.biochi.2015.12.014_bib171","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/j.freeradbiomed.2007.09.009","article-title":"Suppression of atherogenesis by overexpression of glutathione peroxidase-4 in apolipoprotein E-deficient mice","volume":"44","author":"Guo","year":"2008","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.biochi.2015.12.014_bib172","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1161\/01.RES.0000149564.49410.0d","article-title":"Retardation of atherosclerosis by overexpression of catalase or both Cu\/Zn-superoxide dismutase and catalase in mice lacking apolipoprotein E","volume":"95","author":"Yang","year":"2004","journal-title":"Circ. Res."},{"key":"10.1016\/j.biochi.2015.12.014_bib173","doi-asserted-by":"crossref","first-page":"2479","DOI":"10.2174\/1381612033453776","article-title":"Role of heme oxygenase-1 in cardiovascular function","volume":"9","author":"Perrella","year":"2003","journal-title":"Curr. Pharm. Des."},{"key":"10.1016\/j.biochi.2015.12.014_bib174","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1161\/CIRCRESAHA.108.174870","article-title":"Peroxiredoxin1 prevents excessive endothelial activation and early atherosclerosis","volume":"103","author":"Kisucka","year":"2008","journal-title":"Circ. Res."},{"key":"10.1016\/j.biochi.2015.12.014_bib175","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1161\/CIRCRESAHA.111.245530","article-title":"Peroxiredoxin 2 deficiency exacerbates atherosclerosis in apolipoprotein E-deficient mice","volume":"109","author":"Park","year":"2011","journal-title":"Circ. Res."},{"key":"10.1016\/j.biochi.2015.12.014_bib176","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1089\/ars.2012.4549","article-title":"Overexpression of peroxiredoxin 4 attenuates atherosclerosis in apoE knockout mice","volume":"17","author":"Guo","year":"2012","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.biochi.2015.12.014_bib177","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.atherosclerosis.2004.06.007","article-title":"Peroxiredoxin 6 deficiency and atherosclerosis susceptibility in mice: significance of genetic background for assessing atherosclerosis","volume":"177","author":"Wang","year":"2004","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.biochi.2015.12.014_bib178","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.1089\/ars.2012.4757","article-title":"The thioredoxin system as a therapeutic target in human health and disease","volume":"19","author":"Mahmood","year":"2013","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.biochi.2015.12.014_bib179","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.2353\/ajpath.2007.060960","article-title":"Endothelial-specific expression of mitochondrial thioredoxin improves endothelial cell function and reduces atherosclerotic lesions","volume":"170","author":"Zhang","year":"2007","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.biochi.2015.12.014_bib180","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.atherosclerosis.2015.04.805","article-title":"Glutaredoxin 2a overexpression in macrophages promotes mitochondrial dysfunction but has little or no effect on atherogenesis in LDL-receptor null mice","volume":"241","author":"Zamora","year":"2015","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.biochi.2015.12.014_bib181","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1096\/fasebj.11.10.9271366","article-title":"A\u00a0role for UCP-2 as a regulator of mitochondrial H2O2 generation","volume":"11","author":"Negre-Salvayre","year":"1997","journal-title":"Faseb J."},{"key":"10.1016\/j.biochi.2015.12.014_bib182","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1161\/01.CIR.0000051722.66074.60","article-title":"Protective role of UCP-2 in atherosclerosis","volume":"107","author":"Blanc","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.biochi.2015.12.014_bib183","doi-asserted-by":"crossref","first-page":"1866","DOI":"10.1248\/bpb.b14-00201","article-title":"Is hyperuricemia a risk factor for arteriosclerosis? Uric acid and arteriosclerosis in apolipoprotein e-deficient mice","volume":"37","author":"Wakuda","year":"2014","journal-title":"Biol. Pharm. Bull."},{"key":"10.1016\/j.biochi.2015.12.014_bib184","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1093\/rheumatology\/keq037","article-title":"Inflammation, oxidative stress and lipids: the risk triad for atherosclerosis in gout","volume":"49","author":"Krishnan","year":"2010","journal-title":"Rheumatology"},{"key":"10.1016\/j.biochi.2015.12.014_bib185","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/S0021-9150(01)00744-4","article-title":"Increased macrophage glutathione reduces cell-mediated oxidation of LDL and atherosclerosis in apoE-deficient mice","volume":"163","author":"Rosenblat","year":"2002","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.biochi.2015.12.014_bib186","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1161\/CIRCULATIONAHA.107.725275","article-title":"Dietary alpha-lipoic acid supplementation inhibits atherosclerotic lesion development in apoE-deficient and apoE\/LDL-receptor-deficient mice","volume":"117","author":"Zhang","year":"2008","journal-title":"Circulation"},{"key":"10.1016\/j.biochi.2015.12.014_bib187","doi-asserted-by":"crossref","first-page":"138","DOI":"10.3109\/07853890.2014.895588","article-title":"Effects of serum bilirubin on atherosclerotic processes","volume":"46","author":"Kang","year":"2014","journal-title":"Ann. Med."},{"key":"10.1016\/j.biochi.2015.12.014_bib188","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.atherosclerosis.2014.12.042","article-title":"Bilirubin, platelet activation and heart disease: a missing link to cardiovascular protection in Gilbert's syndrome?","volume":"239","author":"Kundur","year":"2015","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.biochi.2015.12.014_bib189","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1007\/s11745-014-3962-z","article-title":"Vitamin E conditionally inhibits atherosclerosis in ApoE knockout mice by anti-oxidation and regulation of vasculature gene expressions","volume":"49","author":"Tang","year":"2014","journal-title":"Lipids"},{"key":"10.1016\/j.biochi.2015.12.014_bib190","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.atherosclerosis.2013.12.006","article-title":"Long-term vitamin E supplementation reduces atherosclerosis and mortality in Ldlr-\/- mice, but not when fed Western style diet","volume":"233","author":"Meydani","year":"2014","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.biochi.2015.12.014_bib191","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/0021-9150(89)90171-8","article-title":"Lack of effect of probucol on atheroma formation in cholesterol-fed rabbits kept at comparable plasma cholesterol levels","volume":"75","author":"Stein","year":"1989","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.biochi.2015.12.014_bib192","doi-asserted-by":"crossref","first-page":"2858","DOI":"10.1172\/JCI119479","article-title":"Paradoxical enhancement of atherosclerosis by probucol treatment in apolipoprotein E-deficient mice","volume":"99","author":"Zhang","year":"1997","journal-title":"J.\u00a0Clin. Invest."},{"key":"10.1016\/j.biochi.2015.12.014_bib193","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1196\/annals.1331.028","article-title":"Vitamin E and cardiovascular disease: observational studies","volume":"1031","author":"Gaziano","year":"2004","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.biochi.2015.12.014_bib194","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1097\/MCA.0000000000000187","article-title":"Antioxidants and coronary artery disease: from pathophysiology to preventive therapy","volume":"26","author":"Leopold","year":"2015","journal-title":"Coron. Artery Dis."},{"key":"10.1016\/j.biochi.2015.12.014_bib195","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1111\/j.1749-6632.1989.tb14928.x","article-title":"Low plasma vitamins E and C. Increased risk of angina in Scottish men","volume":"570","author":"Riemersma","year":"1989","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.biochi.2015.12.014_bib196","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1111\/j.1749-6632.1989.tb14926.x","article-title":"Plasma vitamins E and A inversely correlated to mortality from ischemic heart disease in cross-cultural epidemiology","volume":"570","author":"Gey","year":"1989","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.biochi.2015.12.014_bib197","doi-asserted-by":"crossref","first-page":"714653","DOI":"10.1155\/2013\/714653","article-title":"The role of oxidized LDL in atherosclerosis: the myths and the facts","volume":"2013","author":"Maiolino","year":"2013","journal-title":"Mediat. Inflamm."},{"key":"10.1016\/j.biochi.2015.12.014_bib198","doi-asserted-by":"crossref","first-page":"1508","DOI":"10.1093\/ajcn\/80.6.1508","article-title":"Antioxidant vitamins and coronary heart disease risk: a pooled analysis of 9 cohorts","volume":"80","author":"Knekt","year":"2004","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.biochi.2015.12.014_bib199","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1093\/ajcn\/84.4.880","article-title":"Vitamin-mineral supplementation and the progression of atherosclerosis: a meta-analysis of randomized controlled trials","volume":"84","author":"Bleys","year":"2006","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.biochi.2015.12.014_bib200","doi-asserted-by":"crossref","first-page":"2017","DOI":"10.1016\/S0140-6736(03)13637-9","article-title":"Use of antioxidant vitamins for the prevention of cardiovascular disease: meta-analysis of randomised trials","volume":"361","author":"Vivekananthan","year":"2003","journal-title":"Lancet"},{"key":"10.1016\/j.biochi.2015.12.014_bib201","doi-asserted-by":"crossref","first-page":"e56803","DOI":"10.1371\/journal.pone.0056803","article-title":"Effect of antioxidant vitamin supplementation on cardiovascular outcomes: a meta-analysis of randomized controlled trials","volume":"8","author":"Ye","year":"2013","journal-title":"PloS One"},{"key":"10.1016\/j.biochi.2015.12.014_bib202","doi-asserted-by":"crossref","first-page":"f10","DOI":"10.1136\/bmj.f10","article-title":"Efficacy of vitamin and antioxidant supplements in prevention of cardiovascular disease: systematic review and meta-analysis of randomised controlled trials","volume":"346","author":"Myung","year":"2013","journal-title":"BMJ"},{"key":"10.1016\/j.biochi.2015.12.014_bib203","first-page":"CD009671","article-title":"Selenium supplementation for the primary prevention of cardiovascular disease","volume":"1","author":"Rees","year":"2013","journal-title":"Cochrane Database Syst. Rev."},{"key":"10.1016\/j.biochi.2015.12.014_bib204","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.3945\/ajcn.2010.29673","article-title":"Accruing evidence on benefits of adherence to the Mediterranean diet on health: an updated systematic review and meta-analysis","volume":"92","author":"Sofi","year":"2010","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.biochi.2015.12.014_bib205","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1016\/0002-9149(75)90839-5","article-title":"Pathogenetic mechanisms in atherosclerosis","volume":"35","author":"Walton","year":"1975","journal-title":"Am. J. Cardiol."},{"key":"10.1016\/j.biochi.2015.12.014_bib206","first-page":"45","article-title":"Frequency of aortic atherosclerosis in chronic and acute endocarditis; inflammatory genesis of the atherosclerotic process","volume":"14","author":"Weber","year":"1950","journal-title":"Arch. De Vecchi Anat. Pathol."},{"key":"10.1016\/j.biochi.2015.12.014_bib207","doi-asserted-by":"crossref","first-page":"2107","DOI":"10.1161\/01.CIR.0000014762.06201.06","article-title":"Is the oxidative modification hypothesis relevant to human atherosclerosis? Do the antioxidant trials conducted to date refute the hypothesis?","volume":"105","author":"Steinberg","year":"2002","journal-title":"Circulation"}],"container-title":["Biochimie"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300908415004289?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300908415004289?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,5,31]],"date-time":"2025-05-31T18:11:40Z","timestamp":1748715100000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0300908415004289"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,6]]},"references-count":207,"alternative-id":["S0300908415004289"],"URL":"https:\/\/doi.org\/10.1016\/j.biochi.2015.12.014","relation":{},"ISSN":["0300-9084"],"issn-type":[{"value":"0300-9084","type":"print"}],"subject":[],"published":{"date-parts":[[2016,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Oxidative theory of atherosclerosis and antioxidants","name":"articletitle","label":"Article Title"},{"value":"Biochimie","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biochi.2015.12.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2015 Elsevier B.V. and Soci\u00e9t\u00e9 Fran\u00e7aise de Biochimie et Biologie Mol\u00e9culaire (SFBBM). All rights reserved.","name":"copyright","label":"Copyright"}]}}