{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T10:09:37Z","timestamp":1790762977166,"version":"4.1.0"},"reference-count":90,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T00:00:00Z","timestamp":1567296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T00:00:00Z","timestamp":1567296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,8,9]],"date-time":"2020-08-09T00:00:00Z","timestamp":1596931200000},"content-version":"am","delay-in-days":343,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100006510","name":"Association pour la Recherche sur la Scl\u00e9rose Lat\u00e9rale Amyotrophique et autres Maladies du Motoneurone","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006510","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004794","name":"Centre National de la Recherche Scientifique","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004794","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004794","name":"Centre National de la Recherche Scientifique","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004794","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006510","name":"Association pour la Recherche sur la Scl\u00e9rose Lat\u00e9rale Amyotrophique et autres Maladies du Motoneurone","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006510","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008990","name":"Universit\u00e9 de Lorraine","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008990","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochimie"],"published-print":{"date-parts":[[2019,9]]},"DOI":"10.1016\/j.biochi.2019.04.007","type":"journal-article","created":{"date-parts":[[2019,4,9]],"date-time":"2019-04-09T13:17:58Z","timestamp":1554815878000},"page":"99-104","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":26,"special_numbering":"C","title":["In\u00a0vivo assembly of eukaryotic signal recognition particle: A still enigmatic process involving the SMN complex"],"prefix":"10.1016","volume":"164","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5187-8356","authenticated-orcid":false,"given":"S\u00e9verine","family":"Massenet","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.biochi.2019.04.007_bib1","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1073\/pnas.59.3.777","article-title":"Structure and function of E. coli ribosomes. V. Reconstitution of functionally active 30S ribosomal particles from RNA and proteins","volume":"59","author":"Traub","year":"1968","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.biochi.2019.04.007_bib2","doi-asserted-by":"crossref","first-page":"4713","DOI":"10.1073\/pnas.71.12.4713","article-title":"Total reconstitution of functionally active 50S ribosomal subunits from Escherichia coli","volume":"71","author":"Nierhaus","year":"1974","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.biochi.2019.04.007_bib3","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/0092-8674(83)90385-9","article-title":"Disassembly and reconstitution of signal recognition particle","volume":"34","author":"Walter","year":"1983","journal-title":"Cell"},{"key":"10.1016\/j.biochi.2019.04.007_bib4","doi-asserted-by":"crossref","first-page":"4166","DOI":"10.1093\/nar\/gkf548","article-title":"Reconstitution of the signal recognition particle of the halophilic archaeon Haloferax volcanii","volume":"30","author":"Tozik","year":"2002","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.biochi.2019.04.007_bib5","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1126\/science.1196473","article-title":"The crystal structure of the signal recognition particle in complex with its receptor","volume":"331","author":"Ataide","year":"2011","journal-title":"Science"},{"key":"10.1016\/j.biochi.2019.04.007_bib6","doi-asserted-by":"crossref","first-page":"E5487","DOI":"10.1073\/pnas.1802252115","article-title":"Sequential activation of human signal recognition particle by the ribosome and signal sequence drives efficient protein targeting","volume":"115","author":"Lee","year":"2018","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.biochi.2019.04.007_bib7","doi-asserted-by":"crossref","first-page":"6554","DOI":"10.1128\/MCB.19.10.6554","article-title":"Spliceosomal U snRNP core assembly: Sm proteins assemble onto an Sm site RNA nonanucleotide in a specific and thermodynamically stable manner","volume":"19","author":"Raker","year":"1999","journal-title":"Mol. Cell Biol."},{"key":"10.1016\/j.biochi.2019.04.007_bib8","doi-asserted-by":"crossref","first-page":"4010","DOI":"10.1002\/j.1460-2075.1995.tb00072.x","article-title":"In\u00a0vitro reconstitution of mammalian U2 and U5 snRNPs active in splicing: Sm proteins are functionally interchangeable and are essential for the formation of functional U2 and U5 snRNPs","volume":"14","author":"Segault","year":"1995","journal-title":"EMBO J."},{"key":"10.1016\/j.biochi.2019.04.007_bib9","doi-asserted-by":"crossref","first-page":"3133","DOI":"10.1093\/nar\/gki630","article-title":"Reconstitution of archaeal H\/ACA small ribonucleoprotein complexes active in pseudouridylation","volume":"33","author":"Charpentier","year":"2005","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.biochi.2019.04.007_bib10","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1261\/rna.049791.115","article-title":"Assembly of RNPs: help needed","volume":"21","author":"Fischer","year":"2015","journal-title":"RNA"},{"key":"10.1016\/j.biochi.2019.04.007_bib11","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1038\/nsmb.2939","article-title":"Noncoding RNAs in eukaryotic ribosome biogenesis and function","volume":"22","author":"Lafontaine","year":"2015","journal-title":"Nat. Struct. Mol. Biol."},{"key":"10.1016\/j.biochi.2019.04.007_bib12","first-page":"e1516","article-title":"Maturation of pre-40S particles in yeast and humans, Wiley interdisciplinary reviews","volume":"10","author":"Cerezo","year":"2019","journal-title":"RNA"},{"key":"10.1016\/j.biochi.2019.04.007_bib13","article-title":"Eukaryotic ribosome assembly","author":"Bassler","year":"2018","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.biochi.2019.04.007_bib14","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1007\/s00412-017-0637-6","article-title":"UsnRNP biogenesis: mechanisms and regulation","volume":"126","author":"Gruss","year":"2017","journal-title":"Chromosoma"},{"key":"10.1016\/j.biochi.2019.04.007_bib15","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1080\/15476286.2016.1243646","article-title":"Assembly and trafficking of box C\/D and H\/ACA snoRNPs","volume":"14","author":"Massenet","year":"2017","journal-title":"RNA Biol."},{"key":"10.1016\/j.biochi.2019.04.007_bib16","doi-asserted-by":"crossref","first-page":"4079","DOI":"10.1242\/jcs.204396","article-title":"Targeting and translocation of proteins to the endoplasmic reticulum at a glance","volume":"130","author":"Aviram","year":"2017","journal-title":"J.\u00a0Cell Sci."},{"key":"10.1016\/j.biochi.2019.04.007_bib17","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1080\/09687860400026348","article-title":"Signal recognition particles in chloroplasts, bacteria, yeast and mammals (review)","volume":"22","author":"Pool","year":"2005","journal-title":"Mol. Membr. Biol."},{"key":"10.1016\/j.biochi.2019.04.007_bib18","doi-asserted-by":"crossref","first-page":"508","DOI":"10.4161\/rna.6.5.9753","article-title":"Kinship in the SRP RNA family","volume":"6","author":"Rosenblad","year":"2009","journal-title":"RNA Biol."},{"key":"10.1016\/j.biochi.2019.04.007_bib19","doi-asserted-by":"crossref","first-page":"2392","DOI":"10.1016\/j.bbamcr.2013.02.021","article-title":"Co-translational targeting and translocation of proteins to the endoplasmic reticulum","volume":"1833","author":"Nyathi","year":"2013","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.biochi.2019.04.007_bib20","doi-asserted-by":"crossref","first-page":"7363","DOI":"10.1093\/nar\/11.21.7363","article-title":"The organization of the 7SL RNA in the signal recognition particle","volume":"11","author":"Gundelfinger","year":"1983","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.biochi.2019.04.007_bib21","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1007\/BF01435252","article-title":"Emergence of master sequences in families of retroposons derived from 7sl RNA","volume":"93","author":"Quentin","year":"1994","journal-title":"Genetica"},{"key":"10.1016\/j.biochi.2019.04.007_bib22","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1016\/j.tibs.2016.08.012","article-title":"ATPase and GTPase tangos drive intracellular protein transport","volume":"41","author":"Shan","year":"2016","journal-title":"Trends Biochem. Sci."},{"key":"10.1016\/j.biochi.2019.04.007_bib23","first-page":"365","article-title":"Co-translational protein targeting in bacteria","author":"Steinberg","year":"2018","journal-title":"FEMS Microbiol. Lett."},{"key":"10.1016\/j.biochi.2019.04.007_bib24","doi-asserted-by":"crossref","first-page":"1332","DOI":"10.1038\/nsmb.2421","article-title":"Dynamic switch of the signal recognition particle from scanning to targeting","volume":"19","author":"Holtkamp","year":"2012","journal-title":"Nat. Struct. Mol. Biol."},{"key":"10.1016\/j.biochi.2019.04.007_bib25","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.07975","article-title":"Structures of the scanning and engaged states of the mammalian SRP-ribosome complex","volume":"4","author":"Voorhees","year":"2015","journal-title":"eLife"},{"key":"10.1016\/j.biochi.2019.04.007_bib26","doi-asserted-by":"crossref","first-page":"16265","DOI":"10.1038\/nmicrobiol.2016.265","article-title":"The signal recognition particle contacts uL23 and scans substrate translation inside the ribosomal tunnel","volume":"2","author":"Denks","year":"2017","journal-title":"Nat. Microbiol."},{"key":"10.1016\/j.biochi.2019.04.007_bib27","doi-asserted-by":"crossref","first-page":"11858","DOI":"10.1093\/nar\/gkx888","article-title":"Signal recognition particle binds to translating ribosomes before emergence of a signal anchor sequence","volume":"45","author":"Mercier","year":"2017","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.biochi.2019.04.007_bib28","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1038\/nature02342","article-title":"Structure of the signal recognition particle interacting with the elongation-arrested ribosome","volume":"427","author":"Halic","year":"2004","journal-title":"Nature"},{"key":"10.1016\/j.biochi.2019.04.007_bib29","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/0022-2836(84)90237-7","article-title":"The 4.5 S RNA gene of Escherichia coli is essential for cell growth","volume":"178","author":"Brown","year":"1984","journal-title":"J.\u00a0Mol. Biol."},{"key":"10.1016\/j.biochi.2019.04.007_bib30","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1007\/BF00314874","article-title":"The yeast Yarrowia lipolytica has two, functional, signal recognition particle 7S RNA genes","volume":"17","author":"He","year":"1990","journal-title":"Curr. Genet."},{"key":"10.1016\/j.biochi.2019.04.007_bib31","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1038\/359744a0","article-title":"The E. coli ffh gene is necessary for viability and efficient protein export","volume":"359","author":"Phillips","year":"1992","journal-title":"Nature"},{"key":"10.1016\/j.biochi.2019.04.007_bib32","first-page":"7839","article-title":"The Srp54 GTPase is essential for protein export in the fission yeast Schizosaccharomyces pombe","volume":"14","author":"Althoff","year":"1994","journal-title":"Mol. Cell Biol."},{"key":"10.1016\/j.biochi.2019.04.007_bib33","doi-asserted-by":"crossref","first-page":"3260","DOI":"10.1128\/JB.184.12.3260-3267.2002","article-title":"Vivo analysis of an essential archaeal signal recognition particle in its native host","volume":"184","author":"Rose","year":"2002","journal-title":"J.\u00a0Bacteriol."},{"key":"10.1016\/j.biochi.2019.04.007_bib34","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/0092-8674(91)90577-L","article-title":"The signal recognition particle in S. cerevisiae","volume":"67","author":"Hann","year":"1991","journal-title":"Cell"},{"key":"10.1016\/j.biochi.2019.04.007_bib35","doi-asserted-by":"crossref","first-page":"4390","DOI":"10.1002\/j.1460-2075.1994.tb06759.x","article-title":"Subunits of the Saccharomyces cerevisiae signal recognition particle required for its functional expression","volume":"13","author":"Brown","year":"1994","journal-title":"EMBO J."},{"key":"10.1016\/j.biochi.2019.04.007_bib36","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1128\/JB.01146-06","article-title":"Membrane composition changes and physiological adaptation by Streptococcus mutans signal recognition particle pathway mutants","volume":"189","author":"Hasona","year":"2007","journal-title":"J.\u00a0Bacteriol."},{"key":"10.1016\/j.biochi.2019.04.007_bib37","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1091\/mbc.12.3.577","article-title":"Multifaceted physiological response allows yeast to adapt to the loss of the signal recognition particle-dependent protein-targeting pathway","volume":"12","author":"Mutka","year":"2001","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.biochi.2019.04.007_bib38","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1016\/S0092-8674(05)80012-1","article-title":"SRP samples nascent chains for the presence of signal sequences by interacting with ribosomes at a discrete step during translation elongation","volume":"81","author":"Ogg","year":"1995","journal-title":"Cell"},{"key":"10.1016\/j.biochi.2019.04.007_bib39","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1126\/science.aar3607","article-title":"Defining the physiological role of SRP in protein-targeting efficiency and specificity","volume":"359","author":"Costa","year":"2018","journal-title":"Science"},{"key":"10.1016\/j.biochi.2019.04.007_bib40","doi-asserted-by":"crossref","first-page":"47348","DOI":"10.1074\/jbc.M207736200","article-title":"RNA interference of signal peptide-binding protein SRP54 elicits deleterious effects and protein sorting defects in trypanosomes","volume":"277","author":"Liu","year":"2002","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.biochi.2019.04.007_bib41","doi-asserted-by":"crossref","first-page":"4551","DOI":"10.1242\/jcs.02578","article-title":"The Trypanosoma brucei signal recognition particle lacks the Alu-domain-binding proteins: purification and functional analysis of its binding proteins by RNAi","volume":"118","author":"Lustig","year":"2005","journal-title":"J.\u00a0Cell Sci."},{"key":"10.1016\/j.biochi.2019.04.007_bib42","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1016\/j.cell.2008.02.049","article-title":"SRP keeps polypeptides translocation-competent by slowing translation to match limiting ER-targeting sites","volume":"133","author":"Lakkaraju","year":"2008","journal-title":"Cell"},{"key":"10.1016\/j.biochi.2019.04.007_bib43","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1016\/j.ajhg.2012.03.020","article-title":"Exome sequencing identifies autosomal-dominant SRP72 mutations associated with familial aplasia and myelodysplasia","volume":"90","author":"Kirwan","year":"2012","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.biochi.2019.04.007_bib44","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1182\/blood-2017-12-820308","article-title":"Mutations in the SRP54 gene cause severe congenital neutropenia as well as Shwachman-Diamond-like syndrome","volume":"132","author":"Bellanne-Chantelot","year":"2018","journal-title":"Blood"},{"key":"10.1016\/j.biochi.2019.04.007_bib45","doi-asserted-by":"crossref","first-page":"4090","DOI":"10.1172\/JCI92876","article-title":"Mutations in signal recognition particle SRP54 cause syndromic neutropenia with Shwachman-Diamond-like features","volume":"127","author":"Carapito","year":"2017","journal-title":"J.\u00a0Clin. Investig."},{"key":"10.1016\/j.biochi.2019.04.007_bib46","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/S0959-440X(02)00010-6","article-title":"S-domain assembly of the signal recognition particle","volume":"13","author":"Sauer-Eriksson","year":"2003","journal-title":"Curr. Opin. Struct. Biol."},{"key":"10.1016\/j.biochi.2019.04.007_bib47","doi-asserted-by":"crossref","first-page":"3479","DOI":"10.1093\/emboj\/cdg337","article-title":"Structure, function and evolution of the signal recognition particle","volume":"22","author":"Nagai","year":"2003","journal-title":"EMBO J."},{"key":"10.1016\/j.biochi.2019.04.007_bib48","doi-asserted-by":"crossref","first-page":"1330","DOI":"10.1080\/15476286.2014.996457","article-title":"RNA gymnastics in mammalian signal recognition particle assembly","volume":"11","author":"Wild","year":"2014","journal-title":"RNA Biol."},{"key":"10.1016\/j.biochi.2019.04.007_bib49","doi-asserted-by":"crossref","first-page":"7","DOI":"10.3389\/fmolb.2018.00007","article-title":"Structural changes of RNA in complex with proteins in the SRP","volume":"5","author":"Flores","year":"2018","journal-title":"Front. Mol. Biosci."},{"key":"10.1016\/j.biochi.2019.04.007_bib50","first-page":"777","article-title":"Assembly of the Alu domain of the signal recognition particle (SRP): dimerization of the two protein components is required for efficient binding to SRP RNA","volume":"10","author":"Strub","year":"1990","journal-title":"Mol. Cell Biol."},{"key":"10.1016\/j.biochi.2019.04.007_bib51","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1111\/j.1432-1033.1987.tb10899.x","article-title":"Disassembly and domain structure of the proteins in the signal-recognition particle","volume":"163","author":"Scoulica","year":"1987","journal-title":"Eur. J. Biochem."},{"key":"10.1016\/j.biochi.2019.04.007_bib52","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1083\/jcb.121.5.977","article-title":"Assembly of the 68- and 72-kD proteins of signal recognition particle with 7S RNA","volume":"121","author":"Lutcke","year":"1993","journal-title":"J.\u00a0Cell Biol."},{"key":"10.1016\/j.biochi.2019.04.007_bib53","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1016\/j.jmb.2004.10.087","article-title":"Identification of an RNA-binding domain in human SRP72","volume":"345","author":"Iakhiaeva","year":"2005","journal-title":"J.\u00a0Mol. Biol."},{"key":"10.1016\/j.biochi.2019.04.007_bib54","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1038\/nsb843","article-title":"Induced structural changes of 7SL RNA during the assembly of human signal recognition particle","volume":"9","author":"Kuglstatter","year":"2002","journal-title":"Nat. Struct. Biol."},{"key":"10.1016\/j.biochi.2019.04.007_bib55","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1038\/nature00768","article-title":"Structure of the SRP19 RNA complex and implications for signal recognition particle assembly","volume":"417","author":"Hainzl","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.biochi.2019.04.007_bib56","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1016\/S1097-2765(02)00530-0","article-title":"Crystal structure of SRP19 in complex with the S domain of SRP RNA and its implication for the assembly of the signal recognition particle","volume":"9","author":"Oubridge","year":"2002","journal-title":"Mol. Cell"},{"key":"10.1016\/j.biochi.2019.04.007_bib57","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1038\/88577","article-title":"Visualizing induced fit in early assembly of the human signal recognition particle","volume":"8","author":"Rose","year":"2001","journal-title":"Nat. Struct. Biol."},{"key":"10.1016\/j.biochi.2019.04.007_bib58","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.jmb.2006.12.056","article-title":"Protein-induced conformational changes of RNA during the assembly of human signal recognition particle","volume":"367","author":"Menichelli","year":"2007","journal-title":"J.\u00a0Mol. Biol."},{"key":"10.1016\/j.biochi.2019.04.007_bib59","doi-asserted-by":"crossref","first-page":"8452","DOI":"10.1016\/S0021-9258(19)68864-2","article-title":"Characterization and subcellular localization of 7-8 S RNAs of Novikoff hepatoma","volume":"256","author":"Reddy","year":"1981","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.biochi.2019.04.007_bib60","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1073\/pnas.97.1.55","article-title":"Signal recognition particle components in the nucleolus","volume":"97","author":"Politz","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.biochi.2019.04.007_bib61","doi-asserted-by":"crossref","first-page":"7981","DOI":"10.1073\/pnas.95.14.7981","article-title":"Localization of signal recognition particle RNA in the nucleolus of mammalian cells","volume":"95","author":"Jacobson","year":"1998","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.biochi.2019.04.007_bib62","doi-asserted-by":"crossref","first-page":"3479","DOI":"10.1242\/jcs.114.19.3479","article-title":"Signal recognition particle protein 19 is imported into the nucleus by importin 8 (RanBP8) and transportin","volume":"114","author":"Dean","year":"2001","journal-title":"J.\u00a0Cell Sci."},{"key":"10.1016\/j.biochi.2019.04.007_bib63","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.1016\/S0960-9822(00)00743-0","article-title":"Nuclear export of yeast signal recognition particle lacking Srp54p by the Xpo1p\/Crm1p NES-dependent pathway","volume":"10","author":"Ciufo","year":"2000","journal-title":"Curr. Biol."},{"key":"10.1016\/j.biochi.2019.04.007_bib64","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1083\/jcb.153.4.745","article-title":"Biogenesis of the signal recognition particle (SRP) involves import of SRP proteins into the nucleolus, assembly with the SRP-RNA, and Xpo1p-mediated export","volume":"153","author":"Grosshans","year":"2001","journal-title":"J.\u00a0Cell Biol."},{"key":"10.1016\/j.biochi.2019.04.007_bib65","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1242\/jcs.01726","article-title":"Signal recognition particle assembly in relation to the function of amplified nucleoli of Xenopus oocytes","volume":"118","author":"Sommerville","year":"2005","journal-title":"J.\u00a0Cell Sci."},{"key":"10.1016\/j.biochi.2019.04.007_bib66","doi-asserted-by":"crossref","first-page":"e994","DOI":"10.1038\/cddis.2013.521","article-title":"Plasmodium falciparum signal recognition particle components and anti-parasitic effect of ivermectin in blocking nucleo-cytoplasmic shuttling of SRP","volume":"5","author":"Panchal","year":"2014","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.biochi.2019.04.007_bib67","doi-asserted-by":"crossref","first-page":"14955","DOI":"10.1021\/bi060890g","article-title":"Compartmentalization directs assembly of the signal recognition particle","volume":"45","author":"Maity","year":"2006","journal-title":"Biochemistry"},{"key":"10.1016\/j.biochi.2019.04.007_bib68","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1016\/j.jmb.2007.03.032","article-title":"A\u00a0threefold RNA-protein interface in the signal recognition particle gates native complex assembly","volume":"369","author":"Maity","year":"2007","journal-title":"J.\u00a0Mol. Biol."},{"key":"10.1016\/j.biochi.2019.04.007_bib69","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.11466","article-title":"A\u00a0deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning","volume":"4","author":"Kirli","year":"2015","journal-title":"eLife"},{"key":"10.1016\/j.biochi.2019.04.007_bib70","doi-asserted-by":"crossref","first-page":"5136","DOI":"10.1016\/S0021-9258(18)34646-5","article-title":"Nucleotide sequence of 7 S RNA. Homology to alu DNA and La 4.5 S RNA","volume":"257","author":"Li","year":"1982","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.biochi.2019.04.007_bib71","doi-asserted-by":"crossref","first-page":"6853","DOI":"10.1074\/jbc.273.12.6853","article-title":"Adenylation of small RNAs in human cells. Development of a cell-free system for accurate adenylation on the 3'-end of human signal recognition particle RNA","volume":"273","author":"Sinha","year":"1998","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.biochi.2019.04.007_bib72","doi-asserted-by":"crossref","first-page":"21791","DOI":"10.1074\/jbc.M101905200","article-title":"Purification, characterization, and cloning of the cDNA of human signal recognition particle RNA 3'-adenylating enzyme","volume":"276","author":"Perumal","year":"2001","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.biochi.2019.04.007_bib73","doi-asserted-by":"crossref","first-page":"10698","DOI":"10.1093\/nar\/gku761","article-title":"Integrity of SRP RNA is ensured by La and the nuclear RNA quality control machinery","volume":"42","author":"Leung","year":"2014","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.biochi.2019.04.007_bib74","doi-asserted-by":"crossref","first-page":"35023","DOI":"10.1074\/jbc.273.52.35023","article-title":"Accurate 3' end processing and adenylation of human signal recognition particle RNA and alu RNA in\u00a0vitro","volume":"273","author":"Chen","year":"1998","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.biochi.2019.04.007_bib75","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1038\/nbt.2566","article-title":"Identification of direct targets and modified bases of RNA cytosine methyltransferases","volume":"31","author":"Khoddami","year":"2013","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.biochi.2019.04.007_bib76","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.15252\/embr.201743967","article-title":"Control of box C\/D snoRNP assembly by N(6)-methylation of adenine","volume":"18","author":"Huang","year":"2017","journal-title":"EMBO Rep."},{"key":"10.1016\/j.biochi.2019.04.007_bib77","first-page":"397","article-title":"The box C\/D and H\/ACA snoRNPs: key players in the modification, processing and the dynamic folding of ribosomal RNA, Wiley interdisciplinary reviews","volume":"3","author":"Watkins","year":"2012","journal-title":"RNA"},{"key":"10.1016\/j.biochi.2019.04.007_bib78","doi-asserted-by":"crossref","first-page":"e1006804","DOI":"10.1371\/journal.pgen.1006804","article-title":"Specialized box C\/D snoRNPs act as antisense guides to target RNA base acetylation","volume":"13","author":"Sharma","year":"2017","journal-title":"PLoS Genet."},{"issue":"Pt 4","key":"10.1016\/j.biochi.2019.04.007_bib79","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1242\/jcs.107.4.903","article-title":"Nuclear export of signal recognition particle RNA is a facilitated process that involves the Alu sequence domain","volume":"107","author":"He","year":"1994","journal-title":"J.\u00a0Cell Sci."},{"key":"10.1016\/j.biochi.2019.04.007_bib80","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/j.bbrc.2003.11.126","article-title":"Nuclear export of signal recognition particle RNA in mammalian cells","volume":"313","author":"Alavian","year":"2004","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.biochi.2019.04.007_bib81","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1111\/gtc.12218","article-title":"Exportin-5 mediates nuclear export of SRP RNA in vertebrates","volume":"20","author":"Takeiwa","year":"2015","journal-title":"Genes Cells: devot. Mol. Cell. Mech."},{"key":"10.1016\/j.biochi.2019.04.007_bib82","first-page":"15","article-title":"Spinal muscular atrophy: a motor neuron disorder or a multi-organ disease?","volume":"224","author":"Shababi","year":"2014","journal-title":"J.\u00a0Anat."},{"key":"10.1016\/j.biochi.2019.04.007_bib83","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/0092-8674(95)90460-3","article-title":"Identification and characterization of a spinal muscular atrophy- determining gene [see comments]","volume":"80","author":"Lefebvre","year":"1995","journal-title":"Cell"},{"key":"10.1016\/j.biochi.2019.04.007_bib84","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/j.bbagrm.2016.12.008","article-title":"Diverse role of survival motor neuron protein","volume":"1860","author":"Singh","year":"2017","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.biochi.2019.04.007_bib85","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.semcdb.2014.04.026","article-title":"SMN control of RNP assembly: from post-transcriptional gene regulation to motor neuron disease","volume":"32","author":"Li","year":"2014","journal-title":"Semin. Cell Dev. Biol."},{"key":"10.1016\/j.biochi.2019.04.007_bib86","doi-asserted-by":"crossref","first-page":"3877","DOI":"10.1007\/s00018-018-2849-1","article-title":"The role of survival motor neuron protein (SMN) in protein homeostasis","volume":"75","author":"Chaytow","year":"2018","journal-title":"Cell. Mol. Life Sci.: CMLS"},{"key":"10.1016\/j.biochi.2019.04.007_bib87","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1093\/nar\/gks1224","article-title":"Implication of the SMN complex in the biogenesis and steady state level of the signal recognition particle","volume":"41","author":"Piazzon","year":"2013","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.biochi.2019.04.007_bib88","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1083\/jcb.148.6.1177","article-title":"Gemin4. A novel component of the SMN complex that is found in both gems and nucleoli","volume":"148","author":"Charroux","year":"2000","journal-title":"J.\u00a0Cell Biol."},{"key":"10.1016\/j.biochi.2019.04.007_bib89","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1006\/excr.2001.5186","article-title":"Nuclear gems and Cajal (coiled) bodies in fetal tissues: nucleolar distribution of the spinal muscular atrophy protein, SMN","volume":"265","author":"Young","year":"2001","journal-title":"Exp. Cell Res."},{"key":"10.1016\/j.biochi.2019.04.007_bib90","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/S0006-8993(02)02750-6","article-title":"Survival motor neuron protein in the nucleolus of mammalian neurons","volume":"945","author":"Wehner","year":"2002","journal-title":"Brain Res."}],"container-title":["Biochimie"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300908419301099?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300908419301099?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T01:12:54Z","timestamp":1759540374000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0300908419301099"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9]]},"references-count":90,"alternative-id":["S0300908419301099"],"URL":"https:\/\/doi.org\/10.1016\/j.biochi.2019.04.007","relation":{},"ISSN":["0300-9084"],"issn-type":[{"value":"0300-9084","type":"print"}],"subject":[],"published":{"date-parts":[[2019,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"In\u00a0vivo assembly of eukaryotic signal recognition particle: A still enigmatic process involving the SMN complex","name":"articletitle","label":"Article Title"},{"value":"Biochimie","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biochi.2019.04.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier B.V. and Soci\u00e9t\u00e9 Fran\u00e7aise de Biochimie et Biologie Mol\u00e9culaire (SFBBM). All rights reserved.","name":"copyright","label":"Copyright"}]}}