{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T06:41:59Z","timestamp":1774680119995,"version":"3.50.1"},"reference-count":28,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,9,26]],"date-time":"2023-09-26T00:00:00Z","timestamp":1695686400000},"content-version":"am","delay-in-days":360,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochimie"],"published-print":{"date-parts":[[2022,10]]},"DOI":"10.1016\/j.biochi.2022.07.008","type":"journal-article","created":{"date-parts":[[2022,7,20]],"date-time":"2022-07-20T22:08:35Z","timestamp":1658354915000},"page":"196-203","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["Serum fatty acid profiling in patients with SDHx mutations: New advances on cellular metabolism in SDH deficiency"],"prefix":"10.1016","volume":"201","author":[{"given":"Joseph","family":"Vamecq","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincent","family":"Masso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L\u00e9o-Paul","family":"Bancel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arnaud","family":"Jannin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne-Fr\u00e9d\u00e9rique","family":"Dessein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catherine","family":"Cardot-Bauters","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3926-4487","authenticated-orcid":false,"given":"Pascal","family":"Pigny","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.biochi.2022.07.008_bib1","doi-asserted-by":"crossref","first-page":"1564","DOI":"10.5858\/arpa.2017-0285-RS","article-title":"Succinate dehydrogenase complex: an updated review","volume":"142","author":"Rasheed","year":"2018","journal-title":"Arch. Pathol. Lab Med."},{"key":"10.1016\/j.biochi.2022.07.008_bib2","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1111\/cen.14289","article-title":"A\u00a0review of the tumour spectrum of germline succinate dehydrogenase gene mutations: beyond phaeochromocytoma and paraganglioma","volume":"93","author":"MacFarlane","year":"2020","journal-title":"Clin. Endocrinol."},{"key":"10.1016\/j.biochi.2022.07.008_bib3","doi-asserted-by":"crossref","first-page":"2367","DOI":"10.1210\/jc.2018-01968","article-title":"European network for the study of adrenal tumors (ENS@T), prognosis of malignant pheochromocytoma and paraganglioma (MAPP-Prono study): a European network for the study of adrenal tumors retrospective study","volume":"104","author":"Hescot","year":"2019","journal-title":"J.\u00a0Clin. Endocrinol. Metab."},{"key":"10.1016\/j.biochi.2022.07.008_bib4","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1210\/en.2013-1549","article-title":"Succinate-to-fumarate ratio as a new metabolic marker to detect the presence of SDHB\/D-related paraganglioma: initial experimental and ex\u00a0vivo findings","volume":"155","author":"Lendvai","year":"2014","journal-title":"Endocrinology"},{"key":"10.1016\/j.biochi.2022.07.008_bib5","doi-asserted-by":"crossref","first-page":"3480","DOI":"10.1158\/0008-5472.CAN-20-2936","article-title":"Loss of SDHB promotes dysregulated iron homeostasis, oxidative stress, and sensitivity to ascorbate","volume":"81","author":"Goncalves","year":"2021","journal-title":"Cancer Res."},{"key":"10.1016\/j.biochi.2022.07.008_bib6","article-title":"Emerging considerations on mitochondrial and cytosolic metabolic features in SDH-deficient cancer cells","volume":"26","author":"Vamecq","year":"2021","journal-title":"Mol. Genet. Metab. Rep."},{"key":"10.1016\/j.biochi.2022.07.008_bib7","doi-asserted-by":"crossref","first-page":"2241","DOI":"10.1002\/iub.2367","article-title":"The malate-aspartate shuttle (Borst cycle): how it started and developed into a major metabolic pathway","volume":"72","author":"Borst","year":"2020","journal-title":"IUBMB Life"},{"key":"10.1016\/j.biochi.2022.07.008_bib8","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.biochi.2021.06.018","article-title":"Citrin deficiency: does the reactivation of liver aralar-1 come into play and promote HCC development?","volume":"190","author":"Mention","year":"2021","journal-title":"Biochimie"},{"key":"10.1016\/j.biochi.2022.07.008_bib9","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.cell.2014.06.018","article-title":"A\u00a0mitochondrial expatriate: nuclear pyruvate dehydrogenase","volume":"158","author":"de Boer","year":"2014","journal-title":"Cell"},{"key":"10.1016\/j.biochi.2022.07.008_bib10","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.1126\/science.1164097","article-title":"ATP-citrate lyase links cellular metabolism to histone acetylation","volume":"324","author":"Wellen","year":"2009","journal-title":"Science"},{"key":"10.1016\/j.biochi.2022.07.008_bib11","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/S0167-7306(02)36009-5","article-title":"Fatty acid desaturation and chain elongation in eukaryotes","volume":"36","author":"Cook","year":"2002","journal-title":"N.\u00a0Compr. Biochem."},{"key":"10.1016\/j.biochi.2022.07.008_bib12","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/S0163-7827(02)00067-X","article-title":"Structural and functional organization of the animal fatty acid synthase","volume":"42","author":"Smith","year":"2003","journal-title":"Prog. Lipid Res."},{"key":"10.1016\/j.biochi.2022.07.008_bib13","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1093\/jb\/mvs105","article-title":"Very long-chain fatty acids: elongation, physiology and related disorders","volume":"152","author":"Kihara","year":"2012","journal-title":"J.\u00a0Biochem."},{"key":"10.1016\/j.biochi.2022.07.008_bib14","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.72593","article-title":"Disruption of the TCA cycle reveals an ATF4-dependent integration of redox and amino acid metabolism","volume":"10","author":"Ryan","year":"2021","journal-title":"Elife"},{"key":"10.1016\/j.biochi.2022.07.008_bib15","doi-asserted-by":"crossref","first-page":"3362","DOI":"10.1210\/jc.2019-00175","article-title":"A\u00a0full phenotype of paraganglioma linked to a germline SDHB mosaic mutation","volume":"104","author":"Cardot-Bauters","year":"2019","journal-title":"J.\u00a0Clin. Endocrinol. Metab."},{"key":"10.1016\/j.biochi.2022.07.008_bib16","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/j.bbalip.2014.11.012","article-title":"Targeted lipidomic strategies for oxygenated metabolites of polyunsaturated fatty acids","volume":"1851","author":"Astarita","year":"2015","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.biochi.2022.07.008_bib17","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1210\/clinem\/dgaa954","article-title":"Targeted metabolomics as a tool in discriminating endocrine from primary hypertension","volume":"106","author":"Erlic","year":"2021","journal-title":"J.\u00a0Clin. Endocrinol. Metab."},{"key":"10.1016\/j.biochi.2022.07.008_bib18","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1007\/s10545-017-0064-0","article-title":"Evaluation of C26:0-lysophosphatidylcholine and C26:0-carnitine as diagnostic markers for Zellweger spectrum disorders","volume":"40","author":"Klouwer","year":"2017","journal-title":"J.\u00a0Inherit. Metab. Dis."},{"key":"10.1016\/j.biochi.2022.07.008_bib19","doi-asserted-by":"crossref","first-page":"83","DOI":"10.3389\/fcell.2015.00083","article-title":"Metabolic interplay between peroxisomes and other subcellular organelles including mitochondria and the endoplasmic reticulum","volume":"3","author":"Wanders","year":"2016","journal-title":"Front. Cell Dev. Biol."},{"key":"10.1016\/j.biochi.2022.07.008_bib20","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1016\/j.chembiol.2021.03.012","article-title":"Protein acylation by saturated very long chain fatty acids and endocytosis are involved in necroptosis","volume":"28","author":"Pradhan","year":"2021","journal-title":"Cell Chem. Biol."},{"key":"10.1016\/j.biochi.2022.07.008_bib21","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1016\/j.ajhg.2019.04.010","article-title":"Recurrent germline DLST mutations in individuals with multiple pheochromocytomas and paragangliomas","volume":"104","author":"Remacha","year":"2019","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.biochi.2022.07.008_bib22","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.plipres.2009.12.002","article-title":"The key roles of elongases and desaturases in mammalian fatty acid metabolism: insights from transgenic mice","volume":"49","author":"Guillou","year":"2010","journal-title":"Prog. Lipid Res."},{"key":"10.1016\/j.biochi.2022.07.008_bib23","doi-asserted-by":"crossref","first-page":"3974","DOI":"10.1093\/hmg\/ddr324","article-title":"Integrative genomic analysis reveals somatic mutations in pheochromocytoma and paraganglioma","volume":"20","author":"Burnichon","year":"2011","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.biochi.2022.07.008_bib24","article-title":"\u03b2-Cell succinate dehydrogenase deficiency triggers metabolic dysfunction and insulinopenic diabetes","volume":"26","author":"Lee","year":"2022","journal-title":"Diabetes"},{"key":"10.1016\/j.biochi.2022.07.008_bib25","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1016\/j.cmet.2018.12.023","article-title":"Polyunsaturated fatty acid desaturation is a mechanism for glycolytic NAD+ recycling","volume":"29","author":"Kim","year":"2019","journal-title":"Cell Metabol."},{"key":"10.1016\/j.biochi.2022.07.008_bib26","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1093\/advances\/nmaa142","article-title":"Diet regulation of long-chain PUFA synthesis: role of macronutrients, micronutrients, and polyphenols on \u0394-5\/\u0394-6 desaturases and elongases 2\/5","volume":"12","author":"Gonzalez-Soto","year":"2021","journal-title":"Adv. Nutr."},{"key":"10.1016\/j.biochi.2022.07.008_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.plipres.2019.101008","article-title":"Updates to the n-3 polyunsaturated fatty acid biosynthesis pathway: DHA synthesis rates, tetracosahexaenoic acid and (minimal) retroconversion","volume":"76","author":"Metherel","year":"2019","journal-title":"Prog. Lipid Res."},{"key":"10.1016\/j.biochi.2022.07.008_bib28","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1677\/erc.1.00829","article-title":"Malignant pheochromocytoma: current status and initiatives for future progress","volume":"11","author":"Eisenhofer","year":"2004","journal-title":"Endocr. Relat. Cancer"}],"container-title":["Biochimie"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300908422001845?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300908422001845?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T01:23:15Z","timestamp":1759540995000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0300908422001845"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10]]},"references-count":28,"alternative-id":["S0300908422001845"],"URL":"https:\/\/doi.org\/10.1016\/j.biochi.2022.07.008","relation":{},"ISSN":["0300-9084"],"issn-type":[{"value":"0300-9084","type":"print"}],"subject":[],"published":{"date-parts":[[2022,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Serum fatty acid profiling in patients with SDHx mutations: New advances on cellular metabolism in SDH deficiency","name":"articletitle","label":"Article Title"},{"value":"Biochimie","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biochi.2022.07.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier B.V. and Soci\u00e9t\u00e9 Fran\u00e7aise de Biochimie et Biologie Mol\u00e9culaire (SFBBM). All rights reserved.","name":"copyright","label":"Copyright"}]}}