{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T07:28:37Z","timestamp":1771054117703,"version":"3.50.1"},"reference-count":45,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100005297","name":"Uniwersytet Medyczny w Bialymstoku","doi-asserted-by":"publisher","award":["SUB\/1\/DN\/21\/006\/1118"],"award-info":[{"award-number":["SUB\/1\/DN\/21\/006\/1118"]}],"id":[{"id":"10.13039\/501100005297","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochimie"],"published-print":{"date-parts":[[2023,1]]},"DOI":"10.1016\/j.biochi.2022.09.002","type":"journal-article","created":{"date-parts":[[2022,9,6]],"date-time":"2022-09-06T06:47:21Z","timestamp":1662446841000},"page":"78-91","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Coumestrol as a new substance that may diminish lipid precursors of the inflammation in steatotic primary rat hepatocytes"],"prefix":"10.1016","volume":"204","author":[{"given":"Wiktor","family":"Bzd\u0119ga","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hubert","family":"\u017bywno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adrian","family":"Ko\u0142akowski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Piotr Franciszek","family":"Kurzyna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ewa","family":"Harasim-Symbor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adrian","family":"Chabowski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9274-5488","authenticated-orcid":false,"given":"Karolina","family":"Konstantynowicz-Nowicka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.biochi.2022.09.002_bib1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.21037\/tgh.2019.09.08","volume":"5","author":"Mitra","year":"2020","journal-title":"Transl. Gastroenterol. Hepatol."},{"key":"10.1016\/j.biochi.2022.09.002_bib2","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1093\/advances\/nmaa142","volume":"12","author":"Gonzalez-Soto","year":"2021","journal-title":"Adv. Nutr."},{"key":"10.1016\/j.biochi.2022.09.002_bib3","volume":"7","author":"Valenzuela","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.biochi.2022.09.002_bib4","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1042\/CS20030326","volume":"106","author":"Araya","year":"2004","journal-title":"Clin. Sci. (Lond.)"},{"key":"10.1016\/j.biochi.2022.09.002_bib5","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1016\/j.dld.2020.04.019","volume":"52","author":"Ortiz","year":"2020","journal-title":"Dig. Liver Dis."},{"key":"10.1016\/j.biochi.2022.09.002_bib6","series-title":"Prostaglandins Leukot Essent Fatty Acids 181","author":"Videla","year":"2022"},{"key":"10.1016\/j.biochi.2022.09.002_bib7","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1179\/rer.2000.5.1.45","volume":"5","author":"Mori","year":"2000","journal-title":"Redox Rep."},{"key":"10.1016\/j.biochi.2022.09.002_bib8","doi-asserted-by":"crossref","first-page":"983","DOI":"10.3109\/10715762.2010.492830","volume":"44","author":"Mas","year":"2010","journal-title":"Free Radic. Res."},{"key":"10.1016\/j.biochi.2022.09.002_bib9","volume":"11","author":"Yang","year":"2019","journal-title":"Nutrients"},{"key":"10.1016\/j.biochi.2022.09.002_bib10","doi-asserted-by":"crossref","first-page":"7001","DOI":"10.7314\/APJCP.2014.15.17.7001","volume":"15","author":"Ko","year":"2014","journal-title":"Asian Pac. J. Cancer Prev. APJCP"},{"key":"10.1016\/j.biochi.2022.09.002_bib11","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1289\/ehp.98106581","volume":"106","author":"Hopert","year":"1998","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.biochi.2022.09.002_bib12","doi-asserted-by":"crossref","first-page":"268","DOI":"10.3390\/biom11020268","volume":"11","author":"Zywno","year":"2021","journal-title":"Biomolecules"},{"key":"10.1016\/j.biochi.2022.09.002_bib13","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1055\/a-1143-6024","volume":"52","author":"Li","year":"2020","journal-title":"Horm. Metab. Res."},{"key":"10.1016\/j.biochi.2022.09.002_bib14","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/S0091-679X(08)61797-5","volume":"13","author":"Seglen","year":"1976","journal-title":"Methods Cell Biol."},{"key":"10.1016\/j.biochi.2022.09.002_bib15","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0116858","volume":"10","author":"Konstantynowicz-Nowicka","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.biochi.2022.09.002_bib16","unstructured":"J. Folch, M. Lees, G.S.S.-J. biol Chem, undefined 1957, Researchgate.Net (n.d.)."},{"key":"10.1016\/j.biochi.2022.09.002_bib17","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1111\/apha.12022","volume":"207","author":"Chabowski","year":"2013","journal-title":"Acta Physiol."},{"key":"10.1016\/j.biochi.2022.09.002_bib18","doi-asserted-by":"crossref","first-page":"578","DOI":"10.2174\/1389557520666200103114123","volume":"20","author":"Li","year":"2020","journal-title":"Mini-Rev. Med. Chem."},{"key":"10.1016\/j.biochi.2022.09.002_bib19","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/ijms20153829","volume":"20","author":"Konstantynowicz-Nowicka","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.biochi.2022.09.002_bib20","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1038\/sj.ejcn.1601298","volume":"56","author":"Tarpila","year":"2002","journal-title":"Eur. J. Clin. Nutr."},{"key":"10.1016\/j.biochi.2022.09.002_bib21","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1080\/1028415X.2017.1347373","volume":"21","author":"Freitas","year":"2018","journal-title":"Nutr. Neurosci."},{"key":"10.1016\/j.biochi.2022.09.002_bib22","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1016\/j.cca.2010.01.023","volume":"411","author":"N","year":"2010","journal-title":"Clin. Chim. Acta"},{"key":"10.1016\/j.biochi.2022.09.002_bib23","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1016\/j.bbadis.2009.08.015","volume":"1792","author":"Pettinelli","year":"2009","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.biochi.2022.09.002_bib24","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.jhep.2015.02.019","volume":"63","author":"Francque","year":"2015","journal-title":"J.\u00a0Hepatol."},{"key":"10.1016\/j.biochi.2022.09.002_bib25","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.molmet.2017.12.008","volume":"8","author":"Zarei","year":"2018","journal-title":"Mol. Metabol."},{"key":"10.1016\/j.biochi.2022.09.002_bib26","first-page":"1","author":"Tong","year":"2019","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.biochi.2022.09.002_bib27","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1002\/hep.27289","volume":"60","author":"Scorletti","year":"2014","journal-title":"Hepatology"},{"key":"10.1016\/j.biochi.2022.09.002_bib28","doi-asserted-by":"crossref","DOI":"10.3390\/ijms22158298","volume":"22","author":"Monroy-Ramirez","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.biochi.2022.09.002_bib29","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0210197","volume":"14","author":"Fickler","year":"2019","journal-title":"PLoS One"},{"key":"10.1016\/j.biochi.2022.09.002_bib30","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/biom10081133","volume":"10","author":"Sztolsztener","year":"2020","journal-title":"Biomolecules"},{"key":"10.1016\/j.biochi.2022.09.002_bib31","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0022775","volume":"6","author":"Gorden","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.biochi.2022.09.002_bib32","doi-asserted-by":"crossref","first-page":"1997","DOI":"10.1016\/j.celrep.2017.05.035","volume":"19","author":"ter Horst","year":"2017","journal-title":"Cell Rep."},{"key":"10.1016\/j.biochi.2022.09.002_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.vascn.2019.106651","volume":"101","author":"Jensen","year":"2020","journal-title":"J.\u00a0Pharmacol. Toxicol. Methods"},{"key":"10.1016\/j.biochi.2022.09.002_bib34","doi-asserted-by":"crossref","first-page":"3077","DOI":"10.1073\/pnas.0630588100","volume":"100","author":"Listenberger","year":"2003","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.biochi.2022.09.002_bib35","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0156650","volume":"11","author":"Gonzalez-Paredes","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.biochi.2022.09.002_bib36","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1016\/S0168-8278(03)00347-7","volume":"39","author":"M","year":"2003","journal-title":"J.\u00a0Hepatol."},{"key":"10.1016\/j.biochi.2022.09.002_bib37","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1002\/hep.21108","volume":"43","author":"Yu","year":"2006","journal-title":"Hepatology"},{"key":"10.1016\/j.biochi.2022.09.002_bib38","doi-asserted-by":"crossref","first-page":"1710","DOI":"10.1016\/j.bbadis.2016.06.009","volume":"1862","author":"Moti\u00f1o","year":"2016","journal-title":"Biochim. Biophys. Acta, Mol. Basis Dis."},{"key":"10.1016\/j.biochi.2022.09.002_bib39","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1007\/s40139-015-0093-z","volume":"3","author":"Yang","year":"2015","journal-title":"Curr. Pathobiol. Rep."},{"key":"10.1016\/j.biochi.2022.09.002_bib40","doi-asserted-by":"crossref","first-page":"1946","DOI":"10.1111\/j.1572-0241.2004.40220.x","volume":"99","author":"Satapathy","year":"2004","journal-title":"Am. J. Gastroenterol."},{"key":"10.1016\/j.biochi.2022.09.002_bib41","doi-asserted-by":"crossref","first-page":"1372","DOI":"10.1111\/j.1572-0241.2007.01774.x","volume":"103","author":"Wieckowska","year":"2008","journal-title":"Am. J. Gastroenterol."},{"key":"10.1016\/j.biochi.2022.09.002_bib42","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1111\/j.1365-2249.1994.tb07031.x","volume":"95","author":"Choi","year":"1994","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.biochi.2022.09.002_bib43","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1210\/en.2016-1582","volume":"158","author":"Liu","year":"2017","journal-title":"Endocrinology"},{"key":"10.1016\/j.biochi.2022.09.002_bib44","first-page":"1624","volume":"7","author":"Zeng","year":"2014","journal-title":"Int. J. Clin. Exp. Med."},{"key":"10.1016\/j.biochi.2022.09.002_bib45","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1038\/nrgastro.2010.213","volume":"8","author":"Luedde","year":"2011","journal-title":"Nat. Rev. Gastroenterol. Hepatol."}],"container-title":["Biochimie"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300908422002279?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300908422002279?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T01:25:49Z","timestamp":1759541149000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0300908422002279"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":45,"alternative-id":["S0300908422002279"],"URL":"https:\/\/doi.org\/10.1016\/j.biochi.2022.09.002","relation":{},"ISSN":["0300-9084"],"issn-type":[{"value":"0300-9084","type":"print"}],"subject":[],"published":{"date-parts":[[2023,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Coumestrol as a new substance that may diminish lipid precursors of the inflammation in steatotic primary rat hepatocytes","name":"articletitle","label":"Article Title"},{"value":"Biochimie","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biochi.2022.09.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier B.V. and Soci\u00e9t\u00e9 Fran\u00e7aise de Biochimie et Biologie Mol\u00e9culaire (SFBBM). All rights reserved.","name":"copyright","label":"Copyright"}]}}